>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 37.4 bits (86), Expect = 2e-04 Identities = 44/210 (20%), Positives = 74/210 (35%), Gaps = 9/210 (4%) Query: 486 KQQEKALKNLDSATQSVGVNAIKEQNKANENVQQETKNSQAQETTSSQA-YESVSQSNAQ 544 + E + AT S + E +K E+ E A ETT+ ++SN + Sbjct: 1019 RVDEAPVPPPAPATPSETTETVAENSK-QESKTVEKNEQDATETTAQNREVAKEAKSNVK 1077 Query: 545 TTTQANESIKPQTNNTETQQENAKESQAIEQNRATQEPHAK--EEPKKVSHPDELVYNPK 602 TQ NE + + ETQ KE+ +E+ + K E PK S + Sbjct: 1078 ANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTS--QVSPKQEQ 1135 Query: 603 NHAGLKERQENQEKTPSKGNDEPWIEFAK-LEQARAKAHYQAMVEKEQAKQQAQQ--NAK 659 + + + +E P+ EP + + + + VE+ + N+ Sbjct: 1136 SETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSV 1195 Query: 660 NTNSINTTNKEVEIIDYGYTQNAPAKNRRR 689 N NTT + + N P RR Sbjct: 1196 VENPENTTPATTQPTVNSESSNKPKNRHRR 1225
>adhesinb#Adhesin B signature. Length = 310 Score = 27.5 bits (61), Expect = 0.040 Identities = 9/45 (20%), Positives = 23/45 (51%), Gaps = 4/45 (8%) Query: 147 PTLKERKALIDFIKENNPSDKITLLESSLSERIVYKRSVSEGLGV 191 T + K L++ +++ +ESS+ +R + ++VS+ + Sbjct: 232 GTPDQIKTLVEKLRKTKV--PSLFVESSVDDRPM--KTVSKDTNI 272
>cloacin#Cloacin signature. Length = 551 Score = 37.4 bits (86), Expect = 1e-04 Identities = 35/108 (32%), Positives = 46/108 (42%), Gaps = 27/108 (25%) Query: 5 SGYGVTSNNTGSNGTSANGVNGTSGNNGAKGENGSSGANGANGTSGYQGVGSNPFPPIAG 64 SG +NTG++ TS N +NG G G GA+ SG+ +NP+ +G Sbjct: 2 SGGDGRGHNTGAHSTSGN-INGGPTGLGVGG--------GASDGSGW-SSENNPWGGGSG 51 Query: 65 SGNGSSGSSNSGYTPFMSGGGGIGGMGGGFIPFPYSPGLQNGSGANGS 112 SG G S G GGG G GGG +G+G N S Sbjct: 52 SGIHWGGGSGHG------NGGGNGNSGGG-----------SGTGGNLS 82 Score = 35.1 bits (80), Expect = 9e-04 Identities = 28/94 (29%), Positives = 34/94 (36%), Gaps = 12/94 (12%) Query: 49 SGYQGVGSNPFPPIAGSGNGSSGSSNSGYTPFMSGGGGIGGMGGGFIPFPYSPGLQNGSG 108 SG G G N + +SG+ N G T GGG G G P G G Sbjct: 2 SGGDGRGHN------TGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNP------WGGG 49 Query: 109 ANGSNGTNGVNGANGTNGVNGANGTSGANGNNSA 142 + G +G G + G SG GN SA Sbjct: 50 SGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSA 83 Score = 34.7 bits (79), Expect = 0.001 Identities = 25/99 (25%), Positives = 31/99 (31%), Gaps = 9/99 (9%) Query: 40 SGANGANGTSGYQGVGSNPFPPIAGSGNGSSGSSNSGYTPFMSGGGGIGGMGGGFIPFPY 99 SG +G +G N G G G S SG++ + GG G Sbjct: 2 SGGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSG---------S 52 Query: 100 SPGLQNGSGANGSNGTNGVNGANGTNGVNGANGTSGANG 138 GSG G G +GT G A A G Sbjct: 53 GIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFG 91 Score = 33.1 bits (75), Expect = 0.003 Identities = 20/85 (23%), Positives = 30/85 (35%), Gaps = 10/85 (11%) Query: 64 GSGNGSSGSSNSGYTPFMSGGGGIGGMGGGFIPFPYSPGLQNGSGANGSNGTNGVNGANG 123 G G G + ++S G G+G GG +GSG + N G +G Sbjct: 4 GDGRGHNTGAHSTSGNINGGPTGLGVGGGA----------SDGSGWSSENNPWGGGSGSG 53 Query: 124 TNGVNGANGTSGANGNNSANGGAAS 148 + G+ +G NS G Sbjct: 54 IHWGGGSGHGNGGGNGNSGGGSGTG 78 Score = 32.8 bits (74), Expect = 0.004 Identities = 28/108 (25%), Positives = 43/108 (39%), Gaps = 12/108 (11%) Query: 2 GYTSGYGVTSNNT-------GSNGTSANGVNGTSGNNGAKGENGSSGANGANGTSGYQGV 54 G+ +G TS N G G +++G +S NN G +GS G G G Sbjct: 8 GHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGG 67 Query: 55 GSNPFPPIAGSGNGSSGSSNSGYTPFMSGGGGIGGMGGGFIPFPYSPG 102 N +G G+G+ G+ ++ P G + G G + S G Sbjct: 68 NGN-----SGGGSGTGGNLSAVAAPVAFGFPALSTPGAGGLAVSISAG 110
>PF04335#VirB8 type IV secretion protein Length = 227 Score = 88.0 bits (218), Expect = 2e-22 Identities = 38/224 (16%), Positives = 78/224 (34%), Gaps = 29/224 (12%) Query: 119 ESFKKDELDLSSVFEVQRKNTQMAYRLAIGGLIGVISLSVALAFLMPLKQIEPYFVDFAN 178 F++ ++ ++A+ +A + VA+A L PLK +EPY + Sbjct: 12 AYFEEAASWERDKLAAAERSKKLAWVVAGVAGALATAGVVAVAALTPLKTVEPYVITVDR 71 Query: 179 SDKHFAVIQ--KADSKVDYGEAFLRNLIGSYIMSRETINHIDDKIRLNETIREQSSDEVW 236 + ++ D+ + Y EA + + +Y+ RE + + + S+ Sbjct: 72 NTGEASIAAKLHGDATITYDEAVRKYFLATYVRYREGWIAAAREEYF-DAVMVMSARPEQ 130 Query: 237 KTLEQLVSGKG-----SIYSNSNMDREIKIINISIYKQGKQQNIAVADIVAKVFDRGYLI 291 + +I +N D ++I +S + VA+V+ + Sbjct: 131 DRWSRFYKTDNPQSPQNILANRT-DVFVEIKRVSF----------LGGNVAQVYFTKESV 179 Query: 292 SEKRYRVSLIYHFKPLIQFDYSSMP-------KNPTGFIVDKYS 328 + S I++ P KNP G+ V+ Y Sbjct: 180 TGSN---STKTDAVATIKYKVDGTPSKEVDRFKNPLGYQVESYR 220
>FRAGILYSIN#Fragilysin metallopeptidase (M10C) enterotoxin signature. Length = 405 Score = 27.3 bits (60), Expect = 0.001 Identities = 10/29 (34%), Positives = 16/29 (55%) Query: 1 MKKMQYLAFILVAVLLNACSDKFIEMKKS 29 MK ++ L + A LL ACS++ + S Sbjct: 9 MKNVKLLLMLGTAALLAACSNEADSLTTS 37
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 1045 bits (2705), Expect = 0.0 Identities = 355/569 (62%), Positives = 444/569 (78%), Gaps = 4/569 (0%) Query: 3 KISRKEYVSMYGPTTGDKVRLGDTDLIAEVEHDYTIYGEELKFGGGKTLREGMSQSN-NP 61 ++SR Y +M+GPT GDKVRL DT+L EVE D+T +GEE+KFGGGK +R+GM QS Sbjct: 4 RMSRAAYANMFGPTVGDKVRLADTELFIEVEKDFTTHGEEVKFGGGKVIRDGMGQSQVTR 63 Query: 62 SKEELDLIITNALIVDYTGIYKADIGIKDGKIAGIGKGGNKDMQDGVKNNLSVGPATEAL 121 +D +ITNALI+D+ GI KADIG+KDG+IA IGK GN DMQ GV + VGP TE + Sbjct: 64 EGGAVDTVITNALILDHWGIVKADIGLKDGRIAAIGKAGNPDMQPGV--TIIVGPGTEVI 121 Query: 122 AGEGLIVTAGGIDTHIHFISPQQIPTAFASGVTTMIGGGTGPADGTNATTITPGRRNLKW 181 AGEG IVTAGG+D+HIHFI PQQI A SG+T M+GGGTGPA GT ATT TPG ++ Sbjct: 122 AGEGKIVTAGGMDSHIHFICPQQIEEALMSGLTCMLGGGTGPAHGTLATTCTPGPWHIAR 181 Query: 182 MLRAAEEYSMNLGFLAKGNASNDASLADQIEAGAIGFKIHEDWGTTPSAINHALDVADKY 241 M+ AA+ + MNL F KGNAS +L + + GA K+HEDWGTTP+AI+ L VAD+Y Sbjct: 182 MIEAADAFPMNLAFAGKGNASLPGALVEMVLGGATSLKLHEDWGTTPAAIDCCLSVADEY 241 Query: 242 DVQVAIHTDTLNEAGCVEDTMAAIAGRTMHTFHTEGAGGGHAPDIIKVAGEHNILPASTN 301 DVQV IHTDTLNE+G VEDT+AAI GRT+H +HTEGAGGGHAPDII++ G+ N++P+STN Sbjct: 242 DVQVMIHTDTLNESGFVEDTIAAIKGRTIHAYHTEGAGGGHAPDIIRICGQPNVIPSSTN 301 Query: 302 PTIPFTVNTEAEHMDMLMVCHHLDKSIKEDVQFADSRIRPQTIAAEDTLHDMGIFSITSS 361 PT P+TVNT AEH+DMLMVCHHL +I ED+ FA+SRIR +TIAAED LHD+G FSI SS Sbjct: 302 PTRPYTVNTLAEHLDMLMVCHHLSPTIPEDIAFAESRIRKETIAAEDILHDIGAFSIISS 361 Query: 362 DSQAMGRVGEVITRTWQTADKNKKEFGRLKEEKGDNDNFRIKRYLSKYTINPAIAHGISE 421 DSQAMGRVGEV RTWQTADK K++ GRLKEE GDNDNFR+KRY++KYTINPAIAHG+S Sbjct: 362 DSQAMGRVGEVAIRTWQTADKMKRQRGRLKEETGDNDNFRVKRYIAKYTINPAIAHGLSH 421 Query: 422 YVGSVEVGKVADLVLWSPAFFGVKPNMIIKGGFIALSQMGDANASIPTPQPVYYREMFAH 481 +GS+EVGK ADLVLW+PAFFGVKP+M++ GG IA + MGD NASIPTPQPV+YR MF Sbjct: 422 EIGSLEVGKRADLVLWNPAFFGVKPDMVLLGGTIAAAPMGDPNASIPTPQPVHYRPMFGA 481 Query: 482 HGKAKYDANITFVSQAAYDKGIKEELGLERQVLPVKNCR-NITKKDMQFNDTTAHIEVNP 540 +G+++ ++++TFVSQA+ D G+ LG+ ++++ V+N R I K M N T HIEV+P Sbjct: 482 YGRSRTNSSVTFVSQASLDAGLAGRLGVAKELVAVQNTRGGIGKASMIHNSLTPHIEVDP 541 Query: 541 ETYHVFVDGKEVTSKPATKVSLAQLFSIF 569 ETY V DG+ +T +PAT + +AQ + +F Sbjct: 542 ETYEVRADGELLTCEPATVLPMAQRYFLF 570
>CLENTEROTOXN#Clostridium enterotoxin signature. Length = 319 Score = 26.5 bits (58), Expect = 0.050 Identities = 9/41 (21%), Positives = 16/41 (39%) Query: 2 NVHKNIQTAVAQAQATYKPSVMNTNNYGQMYGVDAMAGYKW 42 ++ K I A + +N+N G +Y + Y W Sbjct: 194 DIEKEILDLAAATERLNLTDALNSNPAGNLYDWRSSNSYPW 234
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 28.5 bits (63), Expect = 0.027 Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 1/48 (2%) Query: 123 GEELTTREKGFKAVKEFLNEQLENIDLNYPNLVVAYEPIWAIGTKKSA 170 E TT K F +K+ LN +L N + N N + EPI+A KK A Sbjct: 855 QAEATTLSKNFSDIKKELNAKLGNFN-NNNNNGLKNEPIYAKVNKKKA 901
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 60.1 bits (145), Expect = 8e-13 Identities = 61/263 (23%), Positives = 109/263 (41%), Gaps = 29/263 (11%) Query: 4 LKGKKGLIVGVANNKSIAYGIAQSCFNQGATL-AFTYLNESLEKRVRPIAQELNSPYVYE 62 ++GK I G A + I +A++ +QGA + A Y E LEK V + E + Sbjct: 6 IEGKIAFITGAA--QGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP 63 Query: 63 LDVSKEEHFKPLYDSVKKDLGSLDFIVHSVAF--------APKEALEGSLLETSKSAFNT 114 DV + +++++G +D +V+ E E + S FN Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 115 AMEISVYSLIELTNTLKPLLNNGASVLTLSYLGSTKYMAHYNVMGLAKAALESAVRYLAV 174 + +S Y + + ++ + +N A V S MA Y +KAA + L + Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTS-------MAAY---ASSKAAAVMFTKCLGL 173 Query: 175 DLGKHNIRVNALSAGPIRT-----LASSGIADFRMILKWNE---INAPLRKNVSLEEVGN 226 +L ++NIR N +S G T L + ++I E PL+K ++ + Sbjct: 174 ELAEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIAD 233 Query: 227 AGMYLLSSLSSGVSGEVHFVDAG 249 A ++L+S + ++ VD G Sbjct: 234 AVLFLVSGQAGHITMHNLCVDGG 256
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 29.7 bits (66), Expect = 0.034 Identities = 13/76 (17%), Positives = 29/76 (38%), Gaps = 1/76 (1%) Query: 63 ENIKTLDEKSGVHLFPKNMDEIKQKFEANKEKFQQSKNY-SEFTEYCRECNPYTAFQGLR 121 + I E G + KN + +N + + Y S ++ +PY+ F+ + Sbjct: 210 DGIPDSLEVEGYTVDVKNKRTFLSPWISNIHEKKGLTKYKSSPEKWSTASDPYSDFEKVT 269 Query: 122 NRVNFPLKNHSLDKFV 137 R++ + + V Sbjct: 270 GRIDKNVSPEARHPLV 285
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 47.1 bits (112), Expect = 7e-08 Identities = 55/271 (20%), Positives = 104/271 (38%), Gaps = 16/271 (5%) Query: 28 LILSGSLTPHQSFQLGIAVLMGYVFGSFLIQFLSPLMSLESIAKISFGLIALSFLICYFD 87 L+ S +T H L + LM + L LS + +S A+ + I Sbjct: 35 LVHSNDVTAHYGILLALYALMQFACAPVLGA-LSDRFGRRPVLLVSLAGAAVDYAI--MA 91 Query: 88 SIPFFW-LWIWRFIAGVASSALMILVAPLSLPYVKENKKALVGGFIFSAVGIGSVFSGFV 146 + PF W L+I R +AG+ + A + +++A GF+ + G G V + Sbjct: 92 TAPFLWVLYIGRIVAGI-TGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVL 150 Query: 147 LPWISSYNIKWAWIFLGGSCLIAFILSLIGLK-----TRSLRKKSVKKEESAFKIPFHL- 200 + ++ + + F+ L R ++ ++F+ + Sbjct: 151 GGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMT 210 Query: 201 ---WLLLISCALNAIGFLPHTLFWVDYLIRHLNISPTTAGTSWALFG-FGATLGSLISGP 256 L+ + + +G +P L WV + + TT G S A FG + ++I+GP Sbjct: 211 VVAALMAVFFIMQLVGQVPAAL-WVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGP 269 Query: 257 MAQKLGAKNANIFILILKSIACFLPIFFHQI 287 +A +LG + A + +I L F + Sbjct: 270 VAARLGERRALMLGMIADGTGYILLAFATRG 300
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.011 Identities = 9/18 (50%), Positives = 11/18 (61%) Query: 8 LILSGPSGAGKSTLTKYL 25 ++L G G GKSTL L Sbjct: 599 VVLEGTGGIGKSTLINTL 616
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 65.5 bits (159), Expect = 2e-13 Identities = 51/292 (17%), Positives = 90/292 (30%), Gaps = 19/292 (6%) Query: 140 ELENLGDLEALVQEEPNNEEQLLPTLNDQEEKEEVREEEKEEVKEEEKEEVKEEEK--EE 197 E+E N Q +E R +E + E E Sbjct: 984 EVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAEN 1043 Query: 198 VKEEEKEEVKETPQEEKPKDDETQESETLKDEEVSKELETQE------ELEIPKEETQET 251 K+E K K E+ + Q E K+ + + + TQ E + +T ET Sbjct: 1044 SKQESKTVEK---NEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTET 1100 Query: 252 KEEKQEKTQEEVKEETQEQVKEQEPIKEETQENKEEKQEKTQDSPSAQELEAMQELVKEI 311 KE + +E+ K ET++ ++ P K+E+ E Q +KE Sbjct: 1101 KETATVEKEEKAKVETEKT--QEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEP 1158 Query: 312 QENSNGQEDKKETQENT--ETPQEKETQKLETPQDQDAEIPQEK----TQEKETQKDHYE 365 Q +N D ++ + T Q + E P+ TQ + + Sbjct: 1159 QSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNK 1218 Query: 366 NIEDIPEPVMAQAMGEELPFLNESVAKIPNNENGTETPKESVIKTPQEKEES 417 V + E + + + T T +V+ + K + Sbjct: 1219 PKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQF 1270
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 191 bits (486), Expect = 3e-63 Identities = 51/172 (29%), Positives = 84/172 (48%), Gaps = 18/172 (10%) Query: 56 GERPLFADRRAMKPNDLITIIVSEKASANYSSS----KDYKSASGGNSTPPRLTYNGLDE 111 G +PLF DRR D +TI++ E SA+ SSS +D K+ G ++ P L GL Sbjct: 61 GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYL--QGLFG 118 Query: 112 RKKQEAQYLDDKNNYNFTKSSNNTNFKGGGSQKKSEDLEIVLSARIIKVLENGNYFIYGN 171 + + + S F G G S L+ + +VL NGN + G Sbjct: 119 NARADVEA------------SGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGE 166 Query: 172 KEVLVDGEKQILKVSGVIRPYDIERNNTIQSKFLADAKIEYTNLGHLSDSNK 223 K++ ++ + ++ SGV+ P I +NT+ S +ADA+IEY G+++++ Sbjct: 167 KQIAINQGTEFIRFSGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQN 218
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 28.0 bits (62), Expect = 0.016 Identities = 15/49 (30%), Positives = 21/49 (42%), Gaps = 3/49 (6%) Query: 102 RGETILKALERIAFE---EFQLNSLHLEVMENNFKAIAFYEKNHYELEG 147 R + + AL A E E L LE + N A FY K+H+ + Sbjct: 102 RKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGA 150
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 27.1 bits (60), Expect = 0.040 Identities = 17/59 (28%), Positives = 25/59 (42%), Gaps = 8/59 (13%) Query: 32 FVIVAWLFRF--KSIAFSILITLLVILVDIWVYSDVRQFLL-DTASSPILLLVALLIKW 87 V VA ++A +L +LV L I D+ + LL D + P+L LL Sbjct: 121 SVAVAMTLAPGWGTLAALLLTWVLVALTFI----DLDKMLLPDQLTLPLLWG-GLLFNL 174
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.008 Identities = 11/23 (47%), Positives = 14/23 (60%) Query: 30 VVALLGESGAGKSTILRILAGLE 52 V L G G GKST++ L GL+ Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLD 620
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 196 bits (500), Expect = 6e-57 Identities = 115/461 (24%), Positives = 190/461 (41%), Gaps = 67/461 (14%) Query: 3 NIRNIAVIAHVDHGKTTLVDGLLSQSGTFSEREKVDE--RVMDSNDLERERGITILSKNT 60 I NI V+AHVD GKTTL + LL SG +E VD+ D+ LER+RGITI + T Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 61 AIYYKDTKINIIDTPGHADFGGEVERVLKMVDGVLLLVDAQEGVMPQTKFVVKKALSFGI 120 + +++TK+NIIDTPGH DF EV R L ++DG +LL+ A++GV QT+ + GI Sbjct: 62 SFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGI 121 Query: 121 CPIVVVNKIDKPAAEPDRVVDEVFDLF---------VAMGASDKQLDFPV-----VYAAA 166 I +NKID+ + V ++ + V + + +F Sbjct: 122 PTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEG 181 Query: 167 RDGYAMKSLDDE----------------------------KKNL--EPLFETILEHVPSP 196 D K + + K N+ + L E I S Sbjct: 182 NDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSS 241 Query: 197 SGSVDEPLQMQIFTLDYDNYVGKIGIARVFNGSVKKNESVLLMKSDGSKENGRITKLIGF 256 + L ++F ++Y ++ R+++G + +SV + KE +IT++ Sbjct: 242 THRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRI----SEKEKIKITEMYTS 297 Query: 257 LGLARTEIENAYAGDIVAIAG--FSAMDV-GDSVVDPINPMPLDPMHLEEPTMSVYFAVN 313 + +I+ AY+G+IV + V GD+ + P +P P + + Sbjct: 298 INGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLPQRERIENP----LPLLQTTVEPS 353 Query: 314 DSPLAGLEGKHVTANKLKDRLLKEMQTNIAMKCEEMGEGKFKVSGRGELQITILAENLRR 373 + + D LL+ + + +S G++Q+ + L+ Sbjct: 354 KPQQREMLLDALLEISDSDPLLRYYVDSAT--------HEIILSFLGKVQMEVTCALLQE 405 Query: 374 E-GFEFSISRPEVIIKEENGVKCEPFEHLVIDTPQDFSGAI 413 + E I P VI E K E H+ + P F +I Sbjct: 406 KYHVEIEIKEPTVIYMERPLKKAEYTIHIEVP-PNPFWASI 445 Score = 41.8 bits (98), Expect = 8e-06 Identities = 20/80 (25%), Positives = 30/80 (37%), Gaps = 1/80 (1%) Query: 396 EPFEHLVIDTPQDFSGAIIERLGKRKAEMKAMNPMSDGYTRLEFEIPARGLIGYRSEFLT 455 EP+ I PQ++ K A + + + L EIPAR + YRS+ Sbjct: 537 EPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQ-LKNNEVILSGEIPARCIQEYRSDLTF 595 Query: 456 DTKGEGVMNHSFLEFRPFSG 475 T G V + +G Sbjct: 596 FTNGRSVCLTELKGYHVTTG 615
>OMS28PORIN#OMS28 porin signature. Length = 257 Score = 27.8 bits (61), Expect = 0.005 Identities = 17/48 (35%), Positives = 30/48 (62%), Gaps = 1/48 (2%) Query: 8 DYKKSQQRKEVDKNLDKVCEKIAENVRNQIEDAKKGICEKVESLKAGL 55 D KK Q+ +V++ LD + K+ E+V +++E ++ E VES AG+ Sbjct: 46 DNKKLDQKDQVNQALDTI-NKVTEDVSSKLEGVRESSLELVESNDAGV 92
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 29.6 bits (66), Expect = 0.037 Identities = 19/60 (31%), Positives = 23/60 (38%), Gaps = 5/60 (8%) Query: 477 KNQNKSALEEIKEFKFPYSKPKPTTETTAEMKEKETKEAVEKETKENDTKEVQETQPKET 536 QN+ +E K T A+ ETKE ETKE T E +E ET Sbjct: 1062 TAQNREVAKE----AKSNVKANTQTNEVAQSGS-ETKETQTTETKETATVEKEEKAKVET 1116
>PF06340#Vibrio cholerae toxin co-regulated pilus biosynthesis protein F (TcpF) Length = 338 Score = 25.3 bits (55), Expect = 0.013 Identities = 9/31 (29%), Positives = 15/31 (48%) Query: 21 FFVKENGSFVVGKAQSNPEDESLELFTIARK 51 F KENG + + P++ ++L I K Sbjct: 160 FLTKENGRYDIVNVGGVPDNTPVKLPAIVSK 190
>PF01206#SirA family protein Length = 76 Score = 26.6 bits (59), Expect = 0.004 Identities = 7/22 (31%), Positives = 12/22 (54%) Query: 19 SGKEIEVLSTKPEMRIDISSFC 40 +G+ + V++T P D SF Sbjct: 31 AGEVLYVMATDPGSVKDFESFS 52
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 1716 bits (4444), Expect = 0.0 Identities = 924/1191 (77%), Positives = 1019/1191 (85%), Gaps = 59/1191 (4%) Query: 1 MTNETIDQTITPDQTPNQTDFVPQRFINNLQVAFIKVDNAVASFDPDQKPIVDKNDRDNR 60 MTNETIDQ Q + F PQ+FINNLQVAF+KVDNAVAS+DPDQKPIVDKNDRDNR Sbjct: 1 MTNETIDQ-----QPQTEAAFNPQQFINNLQVAFLKVDNAVASYDPDQKPIVDKNDRDNR 55 Query: 61 QAFEKISQLREEYANKAIKNPTKKNQYFSDFINKSNDLINKDNLIAVDSSVESFRKFGDQ 120 QAFE ISQLREEY+NKAIKNPTKKNQYFSDFINKSNDLINKDNLI V+SS +SF+KFGDQ Sbjct: 56 QAFEGISQLREEYSNKAIKNPTKKNQYFSDFINKSNDLINKDNLIDVESSTKSFQKFGDQ 115 Query: 121 RYQIFTSWVSLQKDPSKINTQQIQNFMENIIQPPISDDKEKAEFLRSAKQSFAGIIIGNQ 180 RY+IFTSWVS Q DPSKINT+ I+NFMENIIQPPI DDKEKAEFL+SAKQSFAGIIIGNQ Sbjct: 116 RYRIFTSWVSHQNDPSKINTRSIRNFMENIIQPPILDDKEKAEFLKSAKQSFAGIIIGNQ 175 Query: 181 IRSDEKFMGVFDESLKARQEAEKNAEPAGEDWLDIFLSFVFNKKQSSDLKETLNQEPRPD 240 IR+D+KFMGVFDESLK RQEAEKN EP G DWLDIFLSF+F+KKQSSD+KE +NQEP P Sbjct: 176 IRTDQKFMGVFDESLKERQEAEKNGEPTGGDWLDIFLSFIFDKKQSSDVKEAINQEPVPH 235 Query: 241 FEQNLATTTTDIQGLPPEARDLLDERGNFSKFTLGDVEMLDVEGVADKDPNYKFNQLLIH 300 + ++ATTTTDIQGLPPEARDLLDERGNFSKFTLGD+EMLDVEGVAD DPNYKFNQLLIH Sbjct: 236 VQPDIATTTTDIQGLPPEARDLLDERGNFSKFTLGDMEMLDVEGVADIDPNYKFNQLLIH 295 Query: 301 NNALSSVLMGSHSNIEPEKVSLLYGDNGGPEARHDWNATVGYKDQQGSNVATLINAHLNN 360 NNALSSVLMGSH+ IEPEKVSLLYG NGGP ARHDWNATVGYKDQQG+NVAT+IN H+ N Sbjct: 296 NNALSSVLMGSHNGIEPEKVSLLYGGNGGPGARHDWNATVGYKDQQGNNVATIINVHMKN 355 Query: 361 GSGLIIAGNEDGIKNPSFYLYKEDQLTGLKQALSQEEIQNKVDFMEFLAQNNAKLDNLSK 420 GSGL+IAG E GI NPSFYLYKEDQLTG ++ALSQEEIQNK+DFMEFLAQNNAKLDNLS+ Sbjct: 356 GSGLVIAGGEKGINNPSFYLYKEDQLTGSQRALSQEEIQNKIDFMEFLAQNNAKLDNLSE 415 Query: 421 EEKEKFQTEIENFQKDRKAYLDALGNDHIAFVSKKDPNHLALVTEFGNGELSYTLKDYGK 480 +EKEKF+TEI++FQKD KAYLDALGND IAFVSKKD H AL+TEFGNG+LSYTLKDYGK Sbjct: 416 KEKEKFRTEIKDFQKDSKAYLDALGNDRIAFVSKKDTKHSALITEFGNGDLSYTLKDYGK 475 Query: 481 KQDKALDGETKTTLQGSLKYDGVMFVNYSNFKYTNASKSPNKGLGATNGVSHLEANFSKV 540 K DKALD E TLQGSLK+DGVMFV+YSNFKYTNASK+PNKG+G TNGVSHLE F+KV Sbjct: 476 KADKALDREKNVTLQGSLKHDGVMFVDYSNFKYTNASKNPNKGVGVTNGVSHLEVGFNKV 535 Query: 541 AVFNLPNLNNLAITNYIRRDLEDKLLAKGLSPQEANKLIKDFLNSNKEMVGKVSNFNKAV 600 A+FNLP+LNNLAIT+++RR+LEDKL KGLSPQEANKLIKDFL+SNKE+VGK NFNKAV Sbjct: 536 AIFNLPDLNNLAITSFVRRNLEDKLTTKGLSPQEANKLIKDFLSSNKELVGKTLNFNKAV 595 Query: 601 AEAKNTGNYDEVKKAQKDLEKSLRKREHLEKEVAKKLESRNDNKNRMEAKAQANSQKDKI 660 A+AKNTGNYDEVKKAQKDLEKSLRKREHLEKEV KKLES++ NKN+MEAKAQANSQKD+I Sbjct: 596 ADAKNTGNYDEVKKAQKDLEKSLRKREHLEKEVEKKLESKSGNKNKMEAKAQANSQKDEI 655 Query: 661 FALINKEASKEARAAAFDPNLKGIRIELSDKLENINKNLKDFGKSFDELKNGKNNDFSKA 720 FALINKEA+++ARA A+ NLKGI+ ELSDKLEN+NKNLKDF KSFDE KNGKN DFSKA Sbjct: 656 FALINKEANRDARAIAYAQNLKGIKRELSDKLENVNKNLKDFDKSFDEFKNGKNKDFSKA 715 Query: 721 EETLKALKDSVKDLGINPEWISKIENLNAALNDFKNGKNKDFSKVTQAKSDLENSIKDVI 780 EETLKALK SVKDLGINPEWISK+ENLNAALN+FKNGKNKDFSKVTQAKSDLENS+KDVI Sbjct: 716 EETLKALKGSVKDLGINPEWISKVENLNAALNEFKNGKNKDFSKVTQAKSDLENSVKDVI 775 Query: 781 INQKITDKVDNLNQAVSETKLTGDFSKVEQALAELKNLS-------------LDFGKNSD 827 INQK+TDKVDNLNQAVS K TGDFS+VEQALA+LKN S L+ K S+ Sbjct: 776 INQKVTDKVDNLNQAVSVAKATGDFSRVEQALADLKNFSKEQLAQQAQKNESLNARKKSE 835 Query: 828 LQKSVKNGVNGTLVGNGLSKTEATTLTKNFSEIRKELNEKLFGNSNNNNNGLKNNTEPIY 887 + +SVKNGVNGTLVGNGLS+ EATTL+KNFS+I+KELN KL +NNNNNGLKN EPIY Sbjct: 836 IYQSVKNGVNGTLVGNGLSQAEATTLSKNFSDIKKELNAKLGNFNNNNNNGLKN--EPIY 893 Query: 888 AQVNKKKTGQATSPEEPIYAQVAKKVSAKIDQLNEATLAINRKIDRINKIASAGKGVGNF 947 A+VNKKK GQA S EEPIYAQVAKKV+AKID+LN+ +G GV Sbjct: 894 AKVNKKKAGQAASLEEPIYAQVAKKVNAKIDRLNQIA---------------SGLGVV-- 936 Query: 948 SGAERSASPEPIYATIDFDEANQAGFPLRRSAAVNDLSKVGLSREQELTRRIGDLNQAVS 1007 AGFPL+R V+DLSKVGLSR QEL ++I +LNQAVS Sbjct: 937 --------------------GQAAGFPLKRHDKVDDLSKVGLSRNQELAQKIDNLNQAVS 976 Query: 1008 KAKTGYFDNLEQKIDELKDSTKKNALKLWVESAKQVPAGLQAKLDNYATNSHTRINSNVQ 1067 +AK G+F NLEQ ID+LKDSTK N + LWVESAK+VPA L AKLDNYATNSH RINSN++ Sbjct: 977 EAKAGFFGNLEQTIDKLKDSTKHNPMNLWVESAKKVPASLSAKLDNYATNSHIRINSNIK 1036 Query: 1068 TGTINEKATGMLTQKNPEWLKLVNDKIVAHNVGSAHLSEYDKIGFNQKNMKDYSDSFKFS 1127 G INEKATGMLTQKNPEWLKLVNDKIVAHNVGS LSEYDKIGFNQKNMKDYSDSFKFS Sbjct: 1037 NGAINEKATGMLTQKNPEWLKLVNDKIVAHNVGSVPLSEYDKIGFNQKNMKDYSDSFKFS 1096 Query: 1128 TKLNNAVKDIKSSFVQFLTNTFSTGS-YSLMKANVEHGVKNT-TKSGFQKS 1176 TKLNNAVKD S F QFLTN FST S Y L + N EHG+KN TK GFQKS Sbjct: 1097 TKLNNAVKDTNSGFTQFLTNAFSTASYYCLARENAEHGIKNVNTKGGFQKS 1147
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 32.9 bits (75), Expect = 0.008 Identities = 20/88 (22%), Positives = 32/88 (36%), Gaps = 18/88 (20%) Query: 19 EVQKRQFQKIEELKADMQKGVNPFFKVLFDGGNRLFGFPETFIYSSI-------FILFVT 71 + K K+ EL+ +G+ +D F+ SI F + Sbjct: 301 DTAKAIKAKLAELQPFFPQGMK--VLYPYD--------TTPFVQLSIHEVVKTLFEAIML 350 Query: 72 IVLSVILF-QAYEPVLIVAIVIVLVALG 98 + L + LF Q LI I + +V LG Sbjct: 351 VFLVMYLFLQNMRATLIPTIAVPVVLLG 378
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 29.0 bits (64), Expect = 0.024 Identities = 29/119 (24%), Positives = 54/119 (45%), Gaps = 16/119 (13%) Query: 24 AINTALLPSEYKKLVALGFKKIKTFHQRHDEKEVTEEEKKFATNALREKLRNDRARAEQI 83 A+N AL+ +Y++ + K K D KE+ E++K EK + + +A++ Sbjct: 112 AVNFALMTRDYQEFL----KTKKLIVDAPDPKELEEQKKAL------EKEKEAKEQAQKA 161 Query: 84 QKNIEAFEKKNNSSIQKKAAKHKGLQELNETNANPLKDNPNSNSSTETKSNKDDNFDEM 142 QK+ K +++A L+ L +NP + N N S K +++ D+M Sbjct: 162 QKD------KREKRKEERAKNRANLENLTNAMSNPQNLSNNKNLSELIKQQRENELDQM 214
>PF04335#VirB8 type IV secretion protein Length = 227 Score = 119 bits (299), Expect = 5e-35 Identities = 43/205 (20%), Positives = 73/205 (35%), Gaps = 10/205 (4%) Query: 27 KLNKANRTFKRAFYL---SMALNIVAVTSIVMMMPLKKTDIFVYGIDRYTGEFKIVKRSD 83 KL A R+ K A+ + + AL V ++ + PLK + +V +DR TGE I + Sbjct: 24 KLAAAERSKKLAWVVAGVAGALATAGVVAVAALTPLKTVEPYVITVDRNTGEASIAAKLH 83 Query: 84 A-RQIVNSEAVVDSATSKFVSLLFGYSKNSLRDRKDQLMQYCDVSFQTQAMRMFNENIRQ 142 I EAV + +V G+ + + D +M Q + R + + Q Sbjct: 84 GDATITYDEAVRKYFLATYVRYREGWIAAAREEYFDAVMVMSARPEQDRWSRFYKTDNPQ 143 Query: 143 FVDKVRA-EAIISSNIQREKVKDSPLTRLTFFITIKITPDTMENYEYITKKQVTIYYDFA 201 + A + I + +F +T T TI Y Sbjct: 144 SPQNILANRTDVFVEI-KRVSFLGGNVAQVYFTKESVTGSNS----TKTDAVATIKYKVD 198 Query: 202 RGNSSQENLIINPFGFKVFDIQITD 226 S + + NP G++V + Sbjct: 199 GTPSKEVDRFKNPLGYQVESYRADV 223
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 857 bits (2214), Expect = 0.0 Identities = 511/522 (97%), Positives = 515/522 (98%), Gaps = 1/522 (0%) Query: 1 MEQAFFKKIVNCFCLGYLFLSSVIEAAP-DIKNFNRGRVKVVNKKIAYLGDEKPITIWTS 59 M QAFFKKIV CFCLGYLFLSS IEA DIKNFNRGRVKVVNKKIAYLGDEKPITIWTS Sbjct: 1 MGQAFFKKIVGCFCLGYLFLSSAIEAVALDIKNFNRGRVKVVNKKIAYLGDEKPITIWTS 60 Query: 60 LDNVTVIQLEKDETISYITTGFNKGWSIVPNSNHIFIQPKSVKSNLMFEKEAVNFALMTR 119 LDNVTVIQLEKDETISYITTGFNKGWSIVPNSNHIFIQPKSVKSNLMFEKEAVNFALMTR Sbjct: 61 LDNVTVIQLEKDETISYITTGFNKGWSIVPNSNHIFIQPKSVKSNLMFEKEAVNFALMTR 120 Query: 120 DYQEFLKTKKLIVDAPDPKELEEQKKALEKEKEAKEQAQKAQKDKREKRKEERAKNRANL 179 DYQEFLKTKKLIVDAPDPKELEEQKKALEKEKEAKEQAQKAQKDKREKRKEERAKNRANL Sbjct: 121 DYQEFLKTKKLIVDAPDPKELEEQKKALEKEKEAKEQAQKAQKDKREKRKEERAKNRANL 180 Query: 180 ENLTSAMSNPQNLSNNKNLSEFIKQQRENELDQMERLEDMQEQAQANALKQIEELNKKQA 239 ENLT+AMSNPQNLSNNKNLSE IKQQRENELDQMERLEDMQEQAQANALKQIEELNKKQA Sbjct: 181 ENLTNAMSNPQNLSNNKNLSELIKQQRENELDQMERLEDMQEQAQANALKQIEELNKKQA 240 Query: 240 EEAVKQRAKDKINIKTDKSQKSPEDNSIELSPSDSAWRTNLVVRTNKALYQFILRIAQKD 299 EEAV+QRAKDKI+IKTDKSQKSPEDNSIELSPSDSAWRTNLVVRTNKALYQFILRIAQKD Sbjct: 241 EEAVRQRAKDKISIKTDKSQKSPEDNSIELSPSDSAWRTNLVVRTNKALYQFILRIAQKD 300 Query: 300 NFASAYLTVKLEYPQRHEVSSVIEEELKKREEAKRQKELIKQENLNTTAYINRVMMASNE 359 NFASAYLTVKLEYPQRHEVSSVIEEELKKREEAKRQ+ELIKQENLNTTAYINRVMMASNE Sbjct: 301 NFASAYLTVKLEYPQRHEVSSVIEEELKKREEAKRQRELIKQENLNTTAYINRVMMASNE 360 Query: 360 QIINKEKIREEKQKIILDQAKALETQYVHNALKRNPVPRNYNYYQAPEKRSKHIMPSEIF 419 QIINKEKIREEKQKIILDQAKALETQYVHNALKRNPVPRNYNYYQAPEKRSKHIMPSEIF Sbjct: 361 QIINKEKIREEKQKIILDQAKALETQYVHNALKRNPVPRNYNYYQAPEKRSKHIMPSEIF 420 Query: 420 DDGTFTYFGFKNITLQPAIFVVQPDGKLSMTDAAIDPNMTNSGLRWYRVNEIAEKFKLIK 479 DDGTFTYFGFKNITLQPAIFVVQPDGKLSMTDAAIDPNMTNSGLRWYRVNEIAEKFKLIK Sbjct: 421 DDGTFTYFGFKNITLQPAIFVVQPDGKLSMTDAAIDPNMTNSGLRWYRVNEIAEKFKLIK 480 Query: 480 DKALVTVINKGYGKNPLTKNYNIKNYGELERVIKKLPLVRDK 521 DKALVTVINKGYGKNPLTKNYNIKNYGELERVIKKLPLVRDK Sbjct: 481 DKALVTVINKGYGKNPLTKNYNIKNYGELERVIKKLPLVRDK 522
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 39.7 bits (92), Expect = 7e-05 Identities = 32/199 (16%), Positives = 67/199 (33%), Gaps = 4/199 (2%) Query: 5 SQAKTEAEKQECEKLLTPEAKKLLEQQALDCLKNAKTEAEKKRCVKDLPKDLQKKVLAKE 64 Q TE Q E ++ Q + ++ E + ++K+ AK Sbjct: 1055 EQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKV 1114 Query: 65 SVKAYLDCVSQAKTEAEKQECEKLLTPEAKKLLEEAKESLKAYKDCVSQAKTEAEKKECE 124 + + + KQE + + P+A+ E + K+ SQ T A+ ++ Sbjct: 1115 ETEKTQEVPKVTSQVSPKQEQSETVQPQAEPAREN--DPTVNIKEPQSQTNTTADTEQPA 1172 Query: 125 KLLTPEAKKLLEEEAKESVKAYLDCVSQARTEAEKKECEKLLTPEARKKLEEAKESVKAY 184 K + ++ + E + + + T A + + K + SV++ Sbjct: 1173 KETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPK--NRHRRSVRSV 1230 Query: 185 LDCVSQARTEAEKKECEKL 203 V A T + + L Sbjct: 1231 PHNVEPATTSSNDRSTVAL 1249 Score = 39.3 bits (91), Expect = 1e-04 Identities = 40/244 (16%), Positives = 92/244 (37%), Gaps = 10/244 (4%) Query: 37 KNAKTEAEKKRCVKDLP-KDLQKKVLAKESVKAYLDCVSQAKTEAEKQECEKLLTPEAKK 95 + + E+ V + P ++ + + ++KT + ++ T + ++ Sbjct: 1008 PSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNRE 1067 Query: 96 LLEEAKESLKAYKDCVSQAKTEAEKKECEKLLTPE-AKKLLEEEAKESVKAYLDCVSQAR 154 + +EAK ++KA A++ +E KE + T E A EE+AK + + Sbjct: 1068 VAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTS 1127 Query: 155 TEAEKKECEKLLTPEARKKLEEAKESVKAYLDCVSQARTEAEKKECEKLLTPEAKKLLEQ 214 + K+E + + P+A E + + SQ T A+ ++ K + ++ + + Sbjct: 1128 QVSPKQEQSETVQPQAEPAREN--DPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTE 1185 Query: 215 QALDCLKNA------KTDEERKKCLKDLPKDLQKKVLAKESLKAYKDCVSQAKTEAEKKE 268 N+ T + + + K + S+++ V A T + + Sbjct: 1186 STTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRS 1245 Query: 269 CEKL 272 L Sbjct: 1246 TVAL 1249 Score = 38.9 bits (90), Expect = 2e-04 Identities = 34/222 (15%), Positives = 86/222 (38%), Gaps = 7/222 (3%) Query: 221 KNAKTDEERKKCLKDLP-KDLQKKVLAKESLKAYKDCVSQAKTEAEKKECEKLLTPEAKK 279 + ++ E + + P ++ + ++ ++KT + ++ T + ++ Sbjct: 1008 PSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNRE 1067 Query: 280 LLEEAKKSLKAYKDCVSRARNEKEKKECEKLLTPEAKKLLEE--AKESLKAYKDCVSRAR 337 + +EAK ++KA A++ E KE + T E + +E AK + ++ Sbjct: 1068 VAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTS 1127 Query: 338 NEKEKKECEKLLTPEARKLLEQQVLDCLKSAK----TEAEKKRCVKDIPKDLQKKVLAKE 393 K+E + + P+A E +K + T A+ ++ K+ ++++ V Sbjct: 1128 QVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTEST 1187 Query: 394 SVKAYLDCVSKARNEKEKKECEKLLTPEAKKLLEEAKESLKA 435 +V V N + + + K + S+++ Sbjct: 1188 TVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRS 1229 Score = 37.4 bits (86), Expect = 4e-04 Identities = 38/269 (14%), Positives = 80/269 (29%), Gaps = 22/269 (8%) Query: 263 EAEKK----ECEKLLTPEAKKLLEEAKKSLKAYKDCVSRARNEKEKKECEKLLTPEAKKL 318 E EK+ + + TP + + S +R + + + Sbjct: 984 EVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEI---ARVDEAPVPPPAPATPSETTETV 1040 Query: 319 LEEAKESLKAYKDCVSRARNEKEKKECEKLLTPEARKLLEQQVLDCLKSAKTEAEKKRCV 378 E +K+ K + A E + E ++ Q + +S E + Sbjct: 1041 AENSKQESKTVEKNEQDAT-ETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTE 1099 Query: 379 KDIPKDLQKKVLAKESVKAYLDCVSKARNEKEKKECEKLLTPEAKKLLEEAKESLKAYKD 438 ++K+ AK + + K+E + + P+A+ E Sbjct: 1100 TKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVN----- 1154 Query: 439 CLSQARNEEERRACEKLLTPEARKLLEQEVKKSVKAYLDCVSKARNEKEKQECEKLLTPE 498 + + +++ A + E +EQ V +S + E + TP Sbjct: 1155 -IKEPQSQTNTTADTEQPAKETSSNVEQPVTES--------TTVNTGNSVVENPENTTPA 1205 Query: 499 ARKFLAKQVLSCLEKARNEEERRACLKNI 527 + S K R+ R+ N+ Sbjct: 1206 TTQPTVNSESSNKPKNRHRRSVRSVPHNV 1234
>PF07201#Hypersensitivity response secretion protein HrpJ Length = 293 Score = 29.8 bits (67), Expect = 0.023 Identities = 14/76 (18%), Positives = 26/76 (34%), Gaps = 15/76 (19%) Query: 277 APENSKEKLIEELIANSQLIANEEEREKKLLAEKEKQ--------EAELAKY--KLKDLE 326 S + EE+ E +E L K E ++ +Y K+ +LE Sbjct: 44 GTLQSIADMAEEVTF-----VFSERKELSLDKRKLSDSQARVSDVEEQVNQYLSKVPELE 98 Query: 327 NQKKLKALEAELKKKN 342 ++ + L + L Sbjct: 99 QKQNVSELLSLLSNSP 114
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 40.5 bits (95), Expect = 9e-06 Identities = 39/181 (21%), Positives = 70/181 (38%), Gaps = 13/181 (7%) Query: 216 AASIATLSNDERELGVACVDIGGETCNLTIYSGNSIRYNKYLPIGSHHLSTDLSSMLNTP 275 AA+I G VDIGG T + + S N + Y+ + IG + + + Sbjct: 146 AAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRN 205 Query: 276 F------PYAEEVKIKYGDLSFESGEETPSQSVQIPTTGSDGNESHVVPLSKIQNIMRDR 329 + AE +K + G S G+E V+ + ++I +++ Sbjct: 206 YGSLIGEATAERIKHEIG--SAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEP 263 Query: 330 ALETFQIIHRSIQDSGLE---EHLGGGVVLTGGMALMKGIKELAKAHFTNYPVRLAA-PM 385 + +++ E + G+VLTGG AL++ + L T PV +A P+ Sbjct: 264 LTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNLDRLL-MEETGIPVVVAEDPL 322 Query: 386 E 386 Sbjct: 323 T 323
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 29.3 bits (65), Expect = 0.011 Identities = 18/63 (28%), Positives = 33/63 (52%), Gaps = 9/63 (14%) Query: 50 YNRVDDEPILNHERFMQPDYVLVIDPGLVFIENIFANEKEDTTYIITSYLNKEELFEKKP 109 ++R ++P E F P+ + + N+ A+EK D ++++ L+ E FEK P Sbjct: 293 HSRSGEQPKGFTESFKAPE---------LGVGNLGASEKSDVFLVVSTLLHCIEGFEKNP 343 Query: 110 ELK 112 E+K Sbjct: 344 EIK 346
>PF05844#YopD protein Length = 295 Score = 25.0 bits (54), Expect = 0.035 Identities = 13/65 (20%), Positives = 28/65 (43%), Gaps = 1/65 (1%) Query: 10 SVLKANNPHFDKIFEKHNQLDDDIKTAEQQNASDAEVSHMKKQKLKLKDEIHSMIIEYRE 69 L+A F+ + I++ Q + +V + Q ++E+++ I + + Sbjct: 197 VALRAAGRAFESRNGALQVANTVIQSFVQMANASVQVRQGESQASAREEEVNATIGQ-SQ 255 Query: 70 KQKSE 74 KQK E Sbjct: 256 KQKVE 260
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 34.4 bits (79), Expect = 0.001 Identities = 18/75 (24%), Positives = 30/75 (40%), Gaps = 4/75 (5%) Query: 144 PNDTNNEEAPKNTPLKKYAKNLSALAQDNALDPVVGREEEILRVIEILGR--RKKNNPLL 201 + K+ L +QD P+VGR + + +L R + ++ Sbjct: 108 LTELIGIIGRALAEPKRRPSKLEDDSQDGM--PLVGRSAAMQEIYRVLARLMQTDLTLMI 165 Query: 202 IGEAGVGKTSIAEAL 216 GE+G GK +A AL Sbjct: 166 TGESGTGKELVARAL 180
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 225 bits (574), Expect = 1e-78 Identities = 63/148 (42%), Positives = 93/148 (62%) Query: 9 IGIYPGTFDPVTNGHIDIIHRSSELFEKLIVAVAHSSAKNPMFSLDERLKMMQLATKGFK 68 IYPG+FDP+T GH+DII R LF+++ VAV + K PMFS+ ERL+ + A Sbjct: 2 NAIYPGSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPMFSVQERLEQIAKAIAHLP 61 Query: 69 NVECVAFEGLLANLAKEYHCKVLVRGLRVVSDFEYELQMGYANKSLNHELETLYFMPTLQ 128 N + +FEGL N A++ ++RGLRV+SDFE ELQM NK+L +LET++ + + Sbjct: 62 NAQVDSFEGLTVNYARQRQAGAILRGLRVLSDFELELQMANTNKTLASDLETVFLTTSTE 121 Query: 129 NAFISSSIVRSIIAHKGDASHLVPKEIH 156 +F+SSS+V+ + G+ H VP + Sbjct: 122 YSFLSSSLVKEVARFGGNVEHFVPSHVA 149
>ARGDEIMINASE#Bacterial arginine deiminase signature. Length = 409 Score = 25.9 bits (57), Expect = 0.041 Identities = 12/60 (20%), Positives = 25/60 (41%), Gaps = 8/60 (13%) Query: 7 VHIHNLVFETILGILEFERLKPQKISVNLDLFYTQLPN-----KAYLDYIKIQELIQKMM 61 +I +L+ E ++ + L+ + IS + + K Y + I +I KM+ Sbjct: 70 EYIEDLISEVLVSSVA---LENKFISQFILEAEIKTDFTINLLKDYFSSLTIDNMISKMI 126
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 31.8 bits (72), Expect = 0.044 Identities = 49/231 (21%), Positives = 87/231 (37%), Gaps = 19/231 (8%) Query: 1235 EQDYKIIKDFIDKVGENNINLNEQTLNEYFIH-HPENILGHLSLEKTRY---SFEINGEQ 1290 ++ ++ KD ++ N N T N F+ + N++ +K +Y S + Sbjct: 229 KEIVEVCKDLFKEIQSNKFEFNCYTKNNSFVGFYCLNLMSKEDYKKIQYDSSSKLLENFY 288 Query: 1291 IYKYELQALEDKSLDLSQALNQAIEKLPKGVYQYHKTTLKTDALIIDANNERHEEVQKLI 1350 K + L+ KS DL + + I + K + T K + D E + I Sbjct: 289 YAKDKSDRLKSKSSDLQKIVMNNINRCTKKDKILNNTLKKCEDK--DIFKLYGELLTANI 346 Query: 1351 KNLERG-ELVKWDNLYFQLEQNNEIGIFLKPTKTNSKVQDSRLKAYFKIKDALNDL---- 1405 L++G ++ N Y E + + I L KT S+ S K Y K+K + Sbjct: 347 YALKKGLSHIELANYY--SENYDTVKITLDENKTPSQNVQSYYKKYNKLKKSEEAANEQL 404 Query: 1406 --TSAELSPLSS---DLELESKRVRLNLVYDEFVKKFGYLNENKNRKDIKQ 1451 EL+ L S ++ + + E ++ GY+ K K K Sbjct: 405 LQNEEELNYLYSVLTNINNADNYDEIEEIKKELIET-GYIKFKKIYKSKKS 454
>cloacin#Cloacin signature. Length = 551 Score = 37.4 bits (86), Expect = 1e-04 Identities = 28/112 (25%), Positives = 40/112 (35%), Gaps = 27/112 (24%) Query: 192 SGSNGANGNNSNHNAVGSGIDTDGVLGVDGVNGSSSSSGGSVGGYENNFTNHGSTNNNTG 251 SG +G N H+ G+ +NG + G G ++ + S NN G Sbjct: 2 SGGDGRGHNTGAHSTSGN------------INGGPTGLGVGGGA--SDGSGWSSENNPWG 47 Query: 252 GYDNFNNGSLSGGGLGNGGLFPIPFGNGDTNNSNNPTNTTSPTNGSSSNSAT 303 G G G GNGG GNG++ + T G+ S A Sbjct: 48 GGSGSGIHWGGGSGHGNGG------GNGNSGGGSG-------TGGNLSAVAA 86 Score = 29.7 bits (66), Expect = 0.034 Identities = 22/60 (36%), Positives = 26/60 (43%), Gaps = 4/60 (6%) Query: 176 GSNGYGVNGNDGINGSSGSNGANGNNSNHNAVGSGIDTDGVLGVDGVNGSSSSSGGSVGG 235 G G GV G S GS ++ NN GSGI G G G+ +S GGS G Sbjct: 23 GPTGLGVGGG----ASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTG 78
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 35.2 bits (81), Expect = 5e-04 Identities = 9/51 (17%), Positives = 24/51 (47%), Gaps = 4/51 (7%) Query: 125 TVYEIAKKVAQSDTPPYNPVLFYGGTGLGKTHILNAIGNHALEKHKKVVLV 175 +Y + ++ Q+D ++ G +G GK + A+ ++ ++ V + Sbjct: 148 EIYRVLARLMQTDLT----LMITGESGTGKELVARALHDYGKRRNGPFVAI 194
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 113 bits (285), Expect = 3e-29 Identities = 76/401 (18%), Positives = 151/401 (37%), Gaps = 29/401 (7%) Query: 54 KKPPESVLKNTLALDFCLNKFTKNAKILQANIIDNDRILEITGAKDLVYKSENFILRLEM 113 K P + + N N I + L + ++ ++ +N + L + Sbjct: 170 KLNPFDFSYDMIENFTKENSLQLNDNIFSKIFTGVSKTL----SSEICFRLKNNSIDLSL 225 Query: 114 IPKKANLMILDKEKCVIEA--FRFNDRVAKNDILGALPPN-AYEHQEEDLDFKGLLDILE 170 K + + I++ F FN N +G N + + + + +LE Sbjct: 226 SNLKEIVEVCKDLFKEIQSNKFEFNCYTKNNSFVGFYCLNLMSKEDYKKIQYDSSSKLLE 285 Query: 171 KDFLSYQHKE-LEHKKNQIIKRLNTQKERLKEKLEKLEDPKNLQLEAKELQTQASLLLTY 229 + + + L+ K + + K + R +K + L + + + LL Sbjct: 286 NFYYAKDKSDRLKSKSSDLQKIVMNNINRCTKKDKILNNTLKKCEDKDIFKLYGELLTAN 345 Query: 230 QHLINKHESCVVLKDFED---KECVIEIDKSMPLNAFINKKFTLSKKKKQKSQFLYLEEE 286 + + K S + L ++ I +D++ + + + K K+ + + Sbjct: 346 IYALKKGLSHIELANYYSENYDTVKITLDENKTPSQNVQSYYKKYNKLKKSEEAANEQLL 405 Query: 287 NLKEKIAFKENQINYVKGAQEESVLE------------MFMPVKNSKTKRPMSGYEVLYY 334 +E++ + + + + A +E F + SK + + Sbjct: 406 QNEEELNYLYSVLTNINNADNYDEIEEIKKELIETGYIKFKKIYKSKKSKTSKPMHFISK 465 Query: 335 KDFKIGLGKNQKENVKL-LQDARANDLWMHVRDIPGSHLIVFCQKNTPKDEIIMELAKML 393 I +GKN +N L L+ A +D+W H ++IPGSH+IV + P + ++E A + Sbjct: 466 DGIDIYVGKNNIQNDYLTLKFANKHDIWFHTKNIPGSHVIVKNIMDIP-ESTLLEAANLA 524 Query: 394 IKMQKDVFNS-YEIDYTQRKFVKIIKGAN---VIYSKYRTI 430 K +S +DYT+ K VK GA VIYS +TI Sbjct: 525 AYYSKSQNSSNVPVDYTEVKNVKKPNGAKPGMVIYSTNQTI 565 Score = 34.8 bits (80), Expect = 6e-04 Identities = 21/91 (23%), Positives = 48/91 (52%), Gaps = 3/91 (3%) Query: 46 NTPYIGLSKKPPESVLKNTLALDFCLNKFTKNAKILQANIIDNDRILEIT-GAKDLVYKS 104 N P I L+ + +K + L K+ NAKI+ + I+ DRI+ I + D + + Sbjct: 55 NYPRIHLTDLTKPNPIKAPMFCMV-LRKYISNAKIVDIHQINQDRIVVIDFESTDELGFN 113 Query: 105 ENFILRLEMIPKKANLMILDK-EKCVIEAFR 134 + L +E++ + +N+ ++ K + ++++ + Sbjct: 114 SIYSLIIEIMGRHSNMTLIRKRDNIIMDSIK 144
>FLAGELLIN#Flagellin signature. Length = 507 Score = 284 bits (727), Expect = 5e-92 Identities = 130/519 (25%), Positives = 219/519 (42%), Gaps = 18/519 (3%) Query: 2 SFRINTNIAALTSHAVGVQNNRDLSSSLEKLSSGLRINKAADDSSGMAIADSLRSQSANL 61 + INTN +L + ++ LSS++E+LSSGLRIN A DD++G AIA+ S L Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 GQAIRNANDAIGMVQTADKAMDEQIKILDTIKTKAVQAAQDGQTLESRKALQSDIQRLLE 121 QA RNAND I + QT + A++E L ++ +VQA + K++Q +IQ+ LE Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 ELDNIANTTSFNGQQMLSGSFSNKEFQIGAYSNTTVKASIGSTSSDKIGHVRMETSSFSA 181 E+D ++N T FNG ++LS + Q+GA T+ + +G + Sbjct: 121 EIDRVSNQTQFNGVKVLSQDN-QMKIQVGANDGETITIDLQKIDVKSLGLDGFNVN---- 175 Query: 182 EGMLASAAAQNLTEVGLNFKQVNGVNDYKIETVRISTSAGTGIGALSEIINRFSNTLGVR 241 + ++ +FK V G + Y + + +G + + V Sbjct: 176 -----GPKEATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVN 230 Query: 242 ASYNVMATG----GTPVQSGTVKDLTINGVEIGTVNDVHKNDADGRLTNAINSVKDRTGV 297 A+ + T T V T E + K +G T V Sbjct: 231 AANGQLTTDDAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGD-TFDYKGVTFTIDT 289 Query: 298 EASLDIQGRINLHSIDGRAISVHATSASGQVFGGGNFAGISGTQHAVIGRLTLTRTDARD 357 + D G+++ +I+G +++ + S D + Sbjct: 290 KTGNDGNGKVST-TINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKT 348 Query: 358 IIVSGVNFSHVGFHSAQGVAEYTVNLRAVRGIFDANVASAAGANANGAQAETNSQGIGAG 417 S ++ +G ++ TVN + + AG + + + Sbjct: 349 KNESAKLSDLEANNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINE 408 Query: 418 --VTSLKGAMIVMDMADSARTQLDKIRSDMGSVQMELVTTINNISVTQVNVKAAESQIRD 475 + K + DSA +++D +RS +G++Q + I N+ T N+ +A S+I D Sbjct: 409 DAAAAKKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIED 468 Query: 476 VDFAEESANFSKYNILAQSGSFAMAQANAVQQNVLRLLQ 514 D+A E +N SK IL Q+G+ +AQAN V QNVL LL+ Sbjct: 469 ADYATEVSNMSKAQILQQAGTSVLAQANQVPQNVLSLLR 507
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 39.3 bits (91), Expect = 3e-05 Identities = 26/131 (19%), Positives = 48/131 (36%), Gaps = 7/131 (5%) Query: 96 DDQSKKEVAQAQKEAENARDRANKSGIKLE-QEEQKTEQEKQKTEQEKQKTEQEKQKTEQ 154 + EVAQ+ E + + K +E +E+ K E EK + + KQ+ + Sbjct: 1078 ANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSE 1137 Query: 155 EKQRTSNIETSNQ----IKVEQEEQKTIKEQKDLVKEQKDLVKE--QKDLVKEQKDFIKE 208 Q + N IK Q + T + + KE V++ + + + E Sbjct: 1138 TVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVE 1197 Query: 209 TEQNCQENHSQ 219 +N +Q Sbjct: 1198 NPENTTPATTQ 1208 Score = 37.4 bits (86), Expect = 1e-04 Identities = 28/121 (23%), Positives = 54/121 (44%), Gaps = 7/121 (5%) Query: 98 QSKKEVAQAQKEAENARDRANKSGIKLEQEEQKTEQEKQKTEQEKQKTEQEKQKTEQEKQ 157 Q+++ +A+ + + E +E +T + K+ EK+ EK K E EK Sbjct: 1064 QNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKE----EKAKVETEKT 1119 Query: 158 RTSNIETSNQIKVEQEEQKTIKEQKDLVKEQKDLVKEQKDLVKEQKDFIKETEQNCQENH 217 + TS Q+ +QE+ +T++ Q + +E V ++ + +TEQ +E Sbjct: 1120 QEVPKVTS-QVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTT--ADTEQPAKETS 1176 Query: 218 S 218 S Sbjct: 1177 S 1177 Score = 30.4 bits (68), Expect = 0.014 Identities = 28/165 (16%), Positives = 55/165 (33%), Gaps = 8/165 (4%) Query: 95 ADDQSKKEVAQAQKEAENARDRANKSGIKLEQEEQKTEQEKQKTEQEKQKTEQEKQKTEQ 154 KE A +KE + + + + +QE+ +T Q + + +E T Sbjct: 1095 TQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVN 1154 Query: 155 EKQRTSNIETSNQIKVEQEEQKTIKEQKDLVKEQKDLVKEQKDLVKEQKDFIKETEQNCQ 214 K+ S +T+ EQ ++T + V E V +V+ ++ T Q Sbjct: 1155 IKEPQS--QTNTTADTEQPAKETSSNVEQPVTESTT-VNTGNSVVENPENTTPATTQPTV 1211 Query: 215 ENHSQFFIKKLGIKGGIAIEIEAECKTPKPTKTNQTPIQPKHLPN 259 + S K + + +P T+ L + Sbjct: 1212 NSESSNKPKNRH-----RRSVRSVPHNVEPATTSSNDRSTVALCD 1251
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 32.0 bits (72), Expect = 0.006 Identities = 25/167 (14%), Positives = 54/167 (32%), Gaps = 5/167 (2%) Query: 125 KQIELEQEKQKANKSEIELEQERQKTNKSGIELANSQIKAEQERQKTEQEKQKANKSEIE 184 I Q S +E + +++ + +E E KQ++ E Sbjct: 995 TNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKN 1054 Query: 185 LEQQKQKTINTQRDLIKEQKDFIKETEQNCQEKHGQLFIKKTRIKTGITTGIAIEIEAEC 244 + + T + + + + T+ N + G + +T T + E +A+ Sbjct: 1055 EQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKV 1114 Query: 245 KTPKPAK-----TNQTPIQPKHLPNSKQPRSQRGSKAQELIAYLQKE 286 +T K + + +P Q + Q R + I Q + Sbjct: 1115 ETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQ 1161
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 294 bits (754), Expect = 5e-92 Identities = 103/441 (23%), Positives = 183/441 (41%), Gaps = 67/441 (15%) Query: 388 DLEHMNSFKEGEILVTDN-TDPDWEPCMKK-ASAVITNRGGRTCHAAIVAREIGVPAIVG 445 + + + E +++ ++ T D K+ T+ GGRT H+AI++R + +PA+VG Sbjct: 146 ETGSLATIAEETVIIAEDLTPSDTAQLNKQFVKGFATDIGGRTSHSAIMSRSLEIPAVVG 205 Query: 446 VSGATDSLYTGMEITVSCAEGE---------EGYVYAGIYEHEIERVELSNMQETQT--- 493 T+ + G + V EG E ++ E + + + Sbjct: 206 TKEVTEKIQHGDMVIVDGIEGIVIVNPTEEEVKAYEEKRAAFEKQKQEWAKLVGEPSTTK 265 Query: 494 -----KIYINIGNPEKAFSFSQLPNHGVGLARMEMIILNQIKAHPLALVDLHHKKSVKEK 548 ++ NIG P+ G+GL R E + +++ + P Sbjct: 266 DGAHVELAANIGTPKDVDGVLANGGEGIGLYRTEFLYMDRDQ-LPTE------------- 311 Query: 549 NEIENLMAGYANPKDFFVKKIAEGIGMISAAFYPKPVIVRTSDFKSNEYMRMLGGSSYEP 608 E Y K++ + KPV++RT D ++ + L P Sbjct: 312 ---EEQFEAY--------KEVVQ-------RMDGKPVVIRTLDIGGDKELSYL----QLP 349 Query: 609 NEENPMLGYRGASRYYSESYNEAFLWECEALALVREEMGLTNMKVMIPFLRTIEEGKKVL 668 E NP LG+R + F + AL N+KVM P + T+EE ++ Sbjct: 350 KELNPFLGFRAIRLCLE--KQDIFRTQLRALL---RASTYGNLKVMFPMIATLEELRQAK 404 Query: 669 EILRKNNLESGKNG------LEIYIMCELPVNVILADDFLSLFDGFSIGSNDLTQLTLGV 722 I+++ + G +E+ IM E+P + A+ F D FSIG+NDL Q T+ Sbjct: 405 AIMQEEKDKLLSEGVDVSDSIEVGIMVEIPSTAVAANLFAKEVDFFSIGTNDLIQYTMAA 464 Query: 723 DRDSELVSHVFDERNEAMLKMFKKAIEACKRHNKYCGICGQAPSDYPEVTEFLVKEGITS 782 DR +E VS+++ + A+L++ I+A K+ G+CG+ D L+ G+ Sbjct: 465 DRMNERVSYLYQPYHPAILRLVDMVIKAAHSEGKWVGMCGEMAGD-EVAIPLLLGLGLDE 523 Query: 783 ISLNPDSVIPTWNAVAKLEKG 803 S++ S++P + + KL K Sbjct: 524 FSMSATSILPARSQLLKLSKE 544
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 149 bits (377), Expect = 3e-49 Identities = 39/140 (27%), Positives = 75/140 (53%), Gaps = 1/140 (0%) Query: 5 EILKHLQADAIVLFMKVHNFHWNVKGTDFFNVHKATEEIYEEFADMFDDLAERIVQLGHH 64 L ++ +L+ K+H FHW VKG FF +H+ EE+Y+ A+ D +AER++ +G Sbjct: 15 NSLNTQLSNWFLLYSKLHRFHWYVKGPHFFTLHEKFEELYDHAAETVDTIAERLLAIGGQ 74 Query: 65 PLVTLTEALKLTRVKEETKTSFHSKDIFKEILEDYKHLEKEFKELSNTAEKEGDKVTVTY 124 P+ T+ E + + + + + ++ + ++ DYK + E K + AE+ D T Sbjct: 75 PVATVKEYTEHASITDGGNET-SASEMVQALVNDYKQISSESKFVIGLAEENQDNATADL 133 Query: 125 ADDQLAKLQKSIWMLQAHLA 144 + +++K +WML ++L Sbjct: 134 FVGLIEEVEKQVWMLSSYLG 153
>PF06580#Sensor histidine kinase Length = 349 Score = 30.2 bits (68), Expect = 0.014 Identities = 10/71 (14%), Positives = 25/71 (35%), Gaps = 13/71 (18%) Query: 281 IVLQNFLYNAIDAIEALEESEQ-GQVKIEAFIQNEFIVFTIIDNGKEVENKSALFEPFET 339 +++Q + N I + + Q G++ ++ N + + + G + Sbjct: 258 MLVQTLVENGI--KHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTK------- 308 Query: 340 TKLKGNGLGLA 350 + G GL Sbjct: 309 ---ESTGTGLQ 316
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 360 bits (925), Expect = e-126 Identities = 119/345 (34%), Positives = 191/345 (55%), Gaps = 26/345 (7%) Query: 19 AEKIGDIASVVGVRDNQLIGYGLVIGLNGTGDK-SGSKFTMQSISNMLESVNVKISADDI 77 +I DIAS+ RDNQLIGYGLV+GL GTGD S FT QS+ ML+++ + Sbjct: 28 TSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFTEQSMRAMLQNLGITTQGGQS 87 Query: 78 KSKNVAAVMITASLPPFARQGDKIDVQISSIGDAKSIQGGTLVMTPLNAVDGNIYALAQG 137 +KN+AAVM+TA+LPPFA G ++DV +SS+GDA S++GG L+MT L+ DG IYA+AQG Sbjct: 88 NAKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRGGNLIMTSLSGADGQIYAVAQG 147 Query: 138 AITSGN-----------SNNLLSANIINGATIEREVSYDLFHKNAMVLSLKNPNFKNAIQ 186 A+ SA + NGA IERE+ +VL L+NP+F A++ Sbjct: 148 ALIVNGFSAQGDAATLTQGVTTSARVPNGAIIERELPSKFKDSVNLVLQLRNPDFSTAVR 207 Query: 187 VQNTLNKV----FGNKVAIALDPKTIQITRPERFSMVEFLALVQEIPINYSAKNKIIVDE 242 V + +N +G+ +A D + I + +P + +A ++ + + K++++E Sbjct: 208 VADVVNAFARARYGDPIAEPRDSQEIAVQKPRVADLTRLMAEIENLTVETDTPAKVVINE 267 Query: 243 KSGTIVSGVDIMVHPIVVTSQDITLKITKEPLDN--------SKNAQDLDNNMSLDTAHN 294 ++GTIV G D+ + + V+ +T+++T+ P Q + M++ Sbjct: 268 RTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQPAPFSRGQTAVQPQTDIMAMQEGSK 327 Query: 295 TLSSNGKNITIAGVVKALQKIGVSAKGMVSILQALKKSGAISAEM 339 G ++ +V L IG+ A G+++ILQ +K +GA+ AE+ Sbjct: 328 VAIVEGPDLR--TLVAGLNSIGLKADGIIAILQGIKSAGALQAEL 370
>SECA#SecA protein signature. Length = 901 Score = 29.8 bits (67), Expect = 0.028 Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 2/63 (3%) Query: 261 IVFTRTKKEADELHQFLASKNYKSTALHGDMDQRDRRASIMAFKKNDADVLVATDVASRG 320 +V T + ++++ + L K L+ + A+I+A A V +AT++A RG Sbjct: 453 LVGTISIEKSELVSNELTKAGIKHNVLNAKFHANE--AAIVAQAGYPAAVTIATNMAGRG 510 Query: 321 LDI 323 DI Sbjct: 511 TDI 513
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.3 bits (71), Expect = 0.009 Identities = 16/50 (32%), Positives = 21/50 (42%), Gaps = 7/50 (14%) Query: 30 VAIVGESGSGKSSIANIIMRLNPR----FKPHNGEVLFETTNLLKESEEF 75 + I GESG+GK +A + R F N + L ESE F Sbjct: 163 LMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRD---LIESELF 209
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 37.5 bits (87), Expect = 1e-04 Identities = 44/259 (16%), Positives = 87/259 (33%), Gaps = 60/259 (23%) Query: 118 ISSMLFGIFWRLPK--RLDTKMNLESAHKNELENSFQRYDALGVRFEDIAGVNEVKEELL 175 I + G + LPK L + + E + + + + G + +E+ Sbjct: 91 IKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIY 150 Query: 176 EVIDYLKNPKKYQDLGIFLPKGVLLIGPPGVGKTMIAKALASEARVPFFYESGSAFSQIY 235 V+ L L +++ G G GK ++A+AL + F I Sbjct: 151 RVLARLMQTD--------LT--LMITGESGTGKELVARALHDYGK-----RRNGPFVAIN 195 Query: 236 VGAGAKKV--HELFMHAK---------------RHAPSIIFIDEIDALGKARGGHRSDER 278 + A + + ELF H K + +F+DEI + + Sbjct: 196 MAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDM--------PMDA 247 Query: 279 EATLNQLLTEM------DGFLQNDEVVVIGATNQMEVMD-EALLRSKRFDRRIF------ 325 + L ++L + +V ++ ATN+ D + + F ++ Sbjct: 248 QTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNK----DLKQSINQGLFREDLYYRLNVV 303 Query: 326 -ISLPDLLERQSILEKLLE 343 + LP L +R + L+ Sbjct: 304 PLRLPPLRDRAEDIPDLVR 322
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 203 bits (518), Expect = 2e-62 Identities = 68/214 (31%), Positives = 106/214 (49%), Gaps = 25/214 (11%) Query: 26 LAPLLIGGFASGVYADGTDILGLSWGEKSQKVCVHHPWY--ALWSC------DKWEEKTQ 77 + P ++GG A+G A GT L WG K + P +W +++ K Sbjct: 40 IIPAIVGGIATGA-AVGTVSGLLGWGLKQAEEANKTPDKPDKVWRIQAGKGFNEFPNKEY 98 Query: 78 QFTGNQLITKT---WAGGNAANYYHSQNNQ--DITANLKNDNGTYFLSGLYNYTGEENNG 132 + L +K W GNAA +Y ++ Q + +++N GTY LSGL N+TG Sbjct: 99 DLYKSLLSSKIDGGWDWGNAARHYWVKDGQWNKLEVDMQNAVGTYNLSGLINFTG----- 153 Query: 133 GNLNIELGSNTTFDLGAHNGNSFTSWYPNGH--TNVTFSAGTINVNNSVEVGNRVGSGAR 190 G+L++ + T LG NGNSFTS+ + T V F+A I ++N +E+ NRVGSGA Sbjct: 154 GDLDVNMQ-KATLRLGQFNGNSFTSYKDSADRTTRVDFNAKNILIDNFLEINNRVGSGAG 212 Query: 191 THTGTATLNLNANK---VNINSNISAFKTSQVNI 221 + L L A++ N+ IS + + +N+ Sbjct: 213 RKASSTVLTLQASEGITSRENAEISLYDGATLNL 246
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 267 bits (684), Expect = 8e-77 Identities = 74/373 (19%), Positives = 136/373 (36%), Gaps = 43/373 (11%) Query: 2 VSLSGDI-CSSLARVGVGANCSTSGPSYSFKGTTNATNTAFSN--ASGSFTFEENATFSG 58 V L G++ L VG + PSYS T+ T N G + + Sbjct: 251 VKLMGNVWMGRLQYVG-----AYLAPSYSTINTSKVTGEVNFNHLTVGDHNAAQAGIIAS 305 Query: 59 AKLNGGAFIFNKDFSATNNTAFNSGNFNFKGTSSFNNATFSNASYTFNDQATFQNSSFNG 118 K + G + + N A G + K +N T +NA + Q + QN+S Sbjct: 306 NKTHIGTLDLWQS-AGLNIIAPPEGGYKDKPNDKPSNTTQNNAKN--DKQESSQNNSNTQ 362 Query: 119 GTFTFNDQNNQANSAQHPQILFESSSFSGNATTLKGFVHFQQAFNNSNRQLMVQNASFNN 178 N Q Q++ F+G T+ N+N ++ F Sbjct: 363 VINPPNSAQKT--EIQPTQVI--DGPFAGGKNTVVNINRI-----NTNADGTIRVGGFKA 413 Query: 179 ANFNNTGKITIEEEA-SFNNTTFNTSINTNNMTITGSVTLSGK---NDLKNGSTLDFGSS 234 + N + I + + +N S+ N+T G++T+ G N+ G L S+ Sbjct: 414 SLTTNAAHLHIGKGGINLSNQASGRSLLVENLT--GNITVDGPLRVNNQVGGYALAGSSA 471 Query: 235 QVTLTQGTTFNLTSLGSEESVTILNSSGGITYNNLLNHALNSLTSALKTNESSLKPQSFA 294 GT ++ N+ I+ +N +++ T+ K ++ Sbjct: 472 NFEFKAGTD-------TKNGTATFNN--DISLGRFVNLKVDAHTANFKGIDTG------- 515 Query: 295 QGLWDMITYNGVTGQLLNTNAAASKPANSSPSKSSTNPAQVYLVGYKIGDIIYKLQETFS 354 G ++ + ++GVT ++ N N + N + + N V G +G+ + ++ S Sbjct: 516 NGGFNTLDFSGVTNKV-NINKLITASTNVAVKNFNINELVVKTNGVSVGEYTHFSEDIGS 574 Query: 355 HNSIIIQALESGT 367 + I LE+GT Sbjct: 575 QSRINTVRLETGT 587 Score = 52.7 bits (126), Expect = 7e-09 Identities = 70/410 (17%), Positives = 124/410 (30%), Gaps = 72/410 (17%) Query: 481 GTTNGTYSAYHVYITANLRSGNRIGTGGAANLIFNGVDSVNIANATITQHNAGIYSSSMT 540 TT ++A ++ I L NR+G+G A + V ++ + ++ NA I S Sbjct: 184 RTTRVDFNAKNILIDNFLEINNRVGSG-AGRKASSTVLTLQASEGITSRENAEI-SLYDG 241 Query: 541 FSTQSMDNSHNVNGLNPNGMLSVYGAT-----------------FTNQAKDGKFIFNAGK 583 + NS + G G L GA N G A Sbjct: 242 ATLNLASNSVKLMGNVWMGRLQYVGAYLAPSYSTINTSKVTGEVNFNHLTVGDHNA-AQA 300 Query: 584 ATFENTNFNGGSYQFNGDSLNFLNNNQFNSGSFEI----SAKNASFDNANFNNSASFNFN 639 + + G+ LN G ++ N + +NA + S N Sbjct: 301 GIIASNKTHIGTLDLWQS--AGLNIIAPPEGGYKDKPNDKPSNTTQNNAKNDKQESSQNN 358 Query: 640 NSNATTSFVGDFTNANS------------------NLQIAGSAVFGNSANGSQNNANFNN 681 ++ + N+ + G G + N Sbjct: 359 SNTQVINPPNSAQKTEIQPTQVIDGPFAGGKNTVVNINRINTNADGTIRVGGFKASLTTN 418 Query: 682 TGSVNI-SGNATFDNVVFNGPT-------NTSVKGQVTLNNI----TLKNLNAPLSFGDG 729 ++I G N N +V G + +NN L +A F G Sbjct: 419 AAHLHIGKGGINLSNQASGRSLLVENLTGNITVDGPLRVNNQVGGYALAGSSANFEFKAG 478 Query: 730 TITFNAHSVINIAEAITNGNPITLVSSSKEIEYN-NAFSKNLWQLINYQG--HGASSEKL 786 T T N + N I+ G + L + + + +++ G + + KL Sbjct: 479 TDTKNGTATFN--NDISLGRFVNLKVDAHTANFKGIDTGNGGFNTLDFSGVTNKVNINKL 536 Query: 787 VSSAGNG-----------VYDVVYSFNNQTYNFQEIFSPNSISIRRLGVG 825 ++++ N V S T+ ++I S + I+ RL G Sbjct: 537 ITASTNVAVKNFNINELVVKTNGVSVGEYTHFSEDIGSQSRINTVRLETG 586
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 30.8 bits (69), Expect = 0.045 Identities = 54/297 (18%), Positives = 99/297 (33%), Gaps = 43/297 (14%) Query: 9 YEAQKIYITGSIESGNRISSGGG-----ASLNFNGLQGILL---TNATLYNRTAGTQSSS 60 + A+ I I +E NR+ SG G L +GI +LY+ ++ Sbjct: 190 FNAKNILIDNFLEINNRVGSGAGRKASSTVLTLQASEGITSRENAEISLYD------GAT 243 Query: 61 MNFTSNSANIQAQNSYFIDDTAQNGGNPNFSF----NALNLDFSNSSFRGYVGKTQS-VF 115 +N SNS + P++S N G Q+ + Sbjct: 244 LNLASNSVKLMGNVWMGRLQYVGAYLAPSYSTINTSKVTGEVNFNHLTVGDHNAAQAGII 303 Query: 116 KFNATNAINFT-------NSTNLSSGLYQMQAKSVSFDNSNLSVSVGTSSIKANAINLSQ 168 N T+ N G Y+ + SN + + + + ++ N S Sbjct: 304 ASNKTHIGTLDLWQSAGLNIIAPPEGGYKDKPND---KPSNTTQNNAKNDKQESSQNNSN 360 Query: 169 NASINASNHS-------TLDLQGDLNVNDTSSLNLNQSVINVSNNATINDYASLIVNNGS 221 IN N + T + G + +N+N+ N + + + + N + Sbjct: 361 TQVINPPNSAQKTEIQPTQVIDGPFAGGKNTVVNINRINTNADGTIRVGGFKASLTTNAA 420 Query: 222 HLNF-NGAINFNSENITTSLNDSSIVFKGAISLGGQF---NLSNNSSLDFQGSSAIT 274 HL+ G IN +++ SL ++ G I++ G N +L S+ Sbjct: 421 HLHIGKGGINLSNQASGRSLLVENLT--GNITVDGPLRVNNQVGGYALAG-SSANFE 474
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 498 bits (1283), Expect = e-168 Identities = 116/406 (28%), Positives = 206/406 (50%), Gaps = 16/406 (3%) Query: 7 STLNQIEAVGG-NAIKWLSTLMMETKENPLFAPIYLKNHSLHEILGVTKDLQNTASLISN 65 + ++ + A G L TL++++ + +A + S +EI T + I++ Sbjct: 895 NDIDTLYANSGAQGRDLLQTLLIDSHDAG-YARTMIDATSANEITKQLNTATTTLNNIAS 953 Query: 66 PNFRDNATNLLELASYTQQTSRLTKLSDFRTRKGESDFSERLLELKNKRFSD-PNPSEVF 124 + + L L++ SRL LS T +S F++RL LK++RF+ + +EV Sbjct: 954 LEHKTSGLQTLSLSNAMILNSRLVNLSRRHTNHIDS-FAKRLQALKDQRFASLESAAEVL 1012 Query: 125 VKYSQLSKHPNNLWVQGIGGASFISGGNGTLYGLNVGYDRLVK---NVILGGYVAYGYSG 181 +++ + P N+W IGG S SGGN +LYG + G D + I+GG+ +YGYS Sbjct: 1013 YQFAPKYEKPTNVWANAIGGTSLNSGGNASLYGTSAGVDAYLNGEVEAIVGGFGSYGYSS 1072 Query: 182 FN--GNIMHSLANNVDVGMYARAFLKRNEFTLSANETYEGNANNINSSNPLLSVLNQRYS 239 F+ N ++S ANN + G+Y+R F ++EF A + +++N + LL LNQ Y+ Sbjct: 1073 FSNQANSLNSGANNTNFGVYSRIFANQHEFDFEAQGALGSDQSSLNFKSALLRDLNQSYN 1132 Query: 240 YNTWTTSVNGNYGYDFMFKQKSVVLKPQVGLSYHFIGLSGMKGKMNDAAYEQFLMHSNPS 299 Y ++ + +YGYDF F + ++VLKP VG+SY+ +G + K + ++ + + S Sbjct: 1133 YLAYSAATRASYGYDFAFFRNALVLKPSVGVSYNHLGSTNFKSN----SNQKVALKNGAS 1188 Query: 300 NESVLTLNMGLESRKYFGKNSYYFVTARLGRDLLIKSKGGNVVRFVGENTLLYRKGEVFN 359 ++ + + +E+R Y+G SY+++ A + ++ N V R N Sbjct: 1189 SQHLFNASANVEARYYYGDTSYFYMNAGVLQE-FANFGSSNAVSLNTFKVNATRNP--LN 1245 Query: 360 TFASVITGGEMHLWRLMYVNAGVGLKMGLQYQDINITGNVGMRVAF 405 T A V+ GGE+ L + +++N G L + N+GMR +F Sbjct: 1246 THARVMMGGELKLAKEVFLNLGFVYLHNLISNIGHFASNLGMRYSF 1291
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 551 bits (1420), Expect = 0.0 Identities = 179/582 (30%), Positives = 294/582 (50%), Gaps = 66/582 (11%) Query: 11 VDFFIKLNKKQKIALIAAGVLITALLVFLLLYPFKEKDYAQGGYGVLFERLDSSDNALIL 70 +++ +L +I LI AG A++V ++L+ K DY LF L D I+ Sbjct: 13 LEWLNRLRANPRIPLIVAGSAAVAIVVAMVLWA-KTPDYR-----TLFSNLSDQDGGAIV 66 Query: 71 QHLQQNQIPYKILKDD-TILIPKDKVYEERITLASQGIPKTSKVGFEIFDTKDFGATDFD 129 L Q IPY+ I +P DKV+E R+ LA QG+PK VGFE+ D + FG + F Sbjct: 67 AQLTQMNIPYRFANGSGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQFS 126 Query: 130 QNIKLIRAIEGELSRTIESLNPILKANVHIAIPKDSVFVAKEVPPSASVMLKLKPDMKLS 189 + + RA+EGEL+RTIE+L P+ A VH+A+PK S+FV ++ PSASV + L+P L Sbjct: 127 EQVNYQRALEGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLEPGRALD 186 Query: 190 PTQILGIKNLIAAAVPKLTTENVKIVNENGESIGEGDILENSKELALEQLRYKQNFENIL 249 QI + +L+++AV L NV +V+++G + + + + ++L QL++ + E+ + Sbjct: 187 EGQISAVVHLVSSAVAGLPPGNVTLVDQSGHLLTQSNT--SGRDLNDAQLKFANDVESRI 244 Query: 250 ENKIVNILAPIVGGKNKVVARVNAEFDFSQKKSTKETFDPNN-----VVRSEQNLEEKKE 304 + +I IL+PIVG N V A+V A+ DF+ K+ T+E + PN +RS Q ++ Sbjct: 245 QRRIEAILSPIVGNGN-VHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQV 303 Query: 305 GAPKKQVGGVPGVVSN-IGPVQGLKDNKEPEKYEKSQN---------------------- 341 GA GGVPG +SN P P + +QN Sbjct: 304 GAGYP--GGVPGALSNQPAPPNEAPIATPPTNQQNAQNTPQTSTSTNSNSAGPRSTQRNE 361 Query: 342 TTNYEVGKTISEIKGEFGTLVRLNAAVVVDGKYKIALKDGANTLEYEPLSDESLKKINAL 401 T+NYEV +TI K G + RL+ AVVV+ K L DG + PL+ + +K+I L Sbjct: 362 TSNYEVDRTIRHTKMNVGDIERLSVAVVVNYK---TLADG----KPLPLTADQMKQIEDL 414 Query: 402 VKQAIGYNQNRGDDVAVSNFEFNPMAPMLDNATLSEKIMHKTQKVLGSFTPLIKYILVFI 461 ++A+G++ RGD + V N F+ + T E + Q + +++LV + Sbjct: 415 TREAMGFSDKRGDTLNVVNSPFSAVDN-----TGGELPFWQQQSFIDQLLAAGRWLLVLV 469 Query: 462 VLFIFYKKVIVPFSERMLEVVPDEDKEVKSMFEEMDEEEDELNKLGDLRKKVEDQLGLNA 521 V +I ++K + P R +E ++ + E + E L+K L+++ +Q Sbjct: 470 VAWILWRKAVRPQLTRRVEEAKAAQEQAQVRQETEEAVEVRLSKDEQLQQRRANQ----- 524 Query: 522 TFSEEEVRYEIVLEKIRGTLKERPDEIAMLFKLLIKDEISSD 563 + E++ ++IR E D + L+I+ +S+D Sbjct: 525 -----RLGAEVMSQRIR----EMSDNDPRVVALVIRQWMSND 557
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 347 bits (893), Expect = e-121 Identities = 121/338 (35%), Positives = 208/338 (61%), Gaps = 4/338 (1%) Query: 8 KQKAQLDELSMSEKIAILLIQVGEDATGEILRHLDIDSITEISKQIVQLNGTDKQIGAAV 67 K+ + L+ +K AILL+ +G + + ++ ++L + I ++ +I +L ++ V Sbjct: 7 KEILDVSALTGKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKLETITSELKDNV 66 Query: 68 LEEFFAIFQSNQYINTGGLEYARELLTRTLGSEEARKVMDKLTKSLQTQKNFAYLGKIKP 127 L EF + + ++I GG++YARELL ++LG+++A +++ L +LQ+ + F ++ + P Sbjct: 67 LLEFKELMMAQEFIQKGGIDYARELLEKSLGTQKAVDIINNLGSALQS-RPFEFVRRADP 125 Query: 128 QQLADFIINEHPQTIALILAHMEAPNAAETLSYFPDEMKAEISIRMANLGEISPQVVKRV 187 + +FI EHPQTIALIL++++ A+ LS P E++ ++ R+A + SP+VV+ V Sbjct: 126 ANILNFIQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVVREV 185 Query: 188 STVLENKLESLTSYK-IEVGGLRAVAEIFNRLGQKSAKTTLARIESVDNKLAGAIKEMMF 246 VLE KL SL+S GG+ V EI N +K+ K + +E D +LA IK+ MF Sbjct: 186 ERVLEKKLASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPELAEEIKKKMF 245 Query: 247 TFEDISKLDNFAIREILKVADKKDLSLALKTSTQDLTDKFLNNMSSRAAEQFVEEMQYLG 306 FEDI LD+ +I+ +L+ D ++L+ ALK+ + +K NMS RAA E+M++LG Sbjct: 246 VFEDIVLLDDRSIQRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRAASMLKEDMEFLG 305 Query: 307 AVKIKDVDVAQRKIIEIVQSLQEKG--VIQTGEEEDVI 342 + KDV+ +Q+KI+ +++ L+E+G VI G EEDV+ Sbjct: 306 PTRRKDVEESQQKIVSLIRKLEEQGEIVISRGGEEDVL 343 Score = 30.9 bits (70), Expect = 0.006 Identities = 20/103 (19%), Positives = 41/103 (39%), Gaps = 3/103 (2%) Query: 4 KLTPKQKAQLDELSMSEKIAILLIQVGEDATGEILRHLDIDSITEISKQIVQLNGTDKQI 63 + P + + IA++L + IL L + T ++++I ++ T ++ Sbjct: 122 RADPANILNFIQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEV 181 Query: 64 GAA---VLEEFFAIFQSNQYINTGGLEYARELLTRTLGSEEAR 103 VLE+ A S Y + GG++ E++ E Sbjct: 182 VREVERVLEKKLASLSSEDYTSAGGVDNVVEIINMADRKTEKF 224
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 36.3 bits (83), Expect = 7e-05 Identities = 42/187 (22%), Positives = 87/187 (46%), Gaps = 14/187 (7%) Query: 70 ELSSHLVKLQMQFEKAQEES-KALIENAKNDGYKIGFKEGEEKMRNELTHSVNEEKNQLL 128 L L +LQMQ A E+ +A I + G+K G++EG + L + E K+Q Sbjct: 39 SLEQQLAQLQMQ---AHEQGYQAGIAEGRQQGHKQGYQEG---LAQGLEQGLAEAKSQQA 92 Query: 129 HAITALDEKMKKSEDHLMALE----KELSAIAIDIAKEVILKEVEDNSQKVALALAEELL 184 + + + + + L AL+ L +A++ A++VI + ++ + + + L Sbjct: 93 PIHARMQQLVSEFQTTLDALDSVIASRLMQMALEAARQVIGQTPTVDNSALIKQIQQLLQ 152 Query: 185 KNVLDATDIHLKVNPLDYPYLNEHLQNASKI---KLESNEAISKGGVMITSSNGSLDGNL 241 + L + L+V+P D +++ L + +L + + GG +++ G LD ++ Sbjct: 153 QEPLFSGKPQLRVHPDDLQRVDDMLGATLSLHGWRLRGDPTLHPGGCKVSADEGDLDASV 212 Query: 242 MERFKTL 248 R++ L Sbjct: 213 ATRWQEL 219
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 110 bits (277), Expect = 1e-27 Identities = 53/162 (32%), Positives = 87/162 (53%), Gaps = 7/162 (4%) Query: 9 NIRNFSIIAHIDHGKSTLADCLIAECNAIS---NREMTSQVMDTMDIEKERGITIKAQSV 65 I N ++AH+D GK+TL + L+ AI+ + + + D +E++RGITI+ Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 66 RLNYTLKGEDYVLNLIDTPGHVDFSYEVSRSLCSCEGALLVVDATQGVEAQTIANTYIAL 125 + E+ +N+IDTPGH+DF EV RSL +GA+L++ A GV+AQT + Sbjct: 62 SFQW----ENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALR 117 Query: 126 DNHLEILPVINKIDLPNANVVEVKQDIEDTIGIDCSNANEVS 167 + + INKID ++ V QDI++ + + +V Sbjct: 118 KMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVE 159 Score = 82.6 bits (204), Expect = 1e-18 Identities = 50/215 (23%), Positives = 90/215 (41%), Gaps = 17/215 (7%) Query: 167 SAKARLGIKDLLEKIITIIPAPSGDFNAPLKALIYDSWFDNYLGALALVRIMDGSINTDQ 226 SAK +GI +L+E I + + + L ++ + LA +R+ G ++ Sbjct: 220 SAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRD 279 Query: 227 EILVMGTGKKHGVLGLYYPNPLKKIPTKSLECGEIGIV---SLGLKSVTDIAVGDTLTDA 283 + + K + +Y + GEI I+ L L SV +GDT Sbjct: 280 SVRISEKEKI-KITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSV----LGDTKLL- 333 Query: 284 KNPTPKPIEGFMPAKPFVFAGLYPIETDRFEDLREALLKLQLNDCALNFEPESSVALGFG 343 P + IE P + + P + + E L +ALL++ +D L + +S+ Sbjct: 334 --PQRERIEN---PLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATH---E 385 Query: 344 FRVGFLGLLHMEVIKERLEREFGLNLIATAPTVVY 378 + FLG + MEV L+ ++ + + PTV+Y Sbjct: 386 IILSFLGKVQMEVTCALLQEKYHVEIEIKEPTVIY 420 Score = 31.0 bits (70), Expect = 0.015 Identities = 15/75 (20%), Positives = 28/75 (37%), Gaps = 2/75 (2%) Query: 405 IKEPFVRATIITPSEFLGNLMQLLNNKRGIQEKMEYLNQSRVMLTYSLPSNEIVMDFYDK 464 + EP++ I P E+L + L + V+L+ +P+ I ++ Sbjct: 535 LLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQ-LKNNEVILSGEIPARCI-QEYRSD 592 Query: 465 LKSCTKGYASFDYEP 479 L T G + E Sbjct: 593 LTFFTNGRSVCLTEL 607
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 30.3 bits (68), Expect = 0.008 Identities = 9/40 (22%), Positives = 16/40 (40%) Query: 3 NGYYAATGAMATQFNRLDLTSNNLANLNTNGFKRDDAITG 42 + A + L+ SNN+++ N G+ R I Sbjct: 2 SLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMA 41
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 39.5 bits (92), Expect = 2e-05 Identities = 57/315 (18%), Positives = 104/315 (33%), Gaps = 67/315 (21%) Query: 35 APYFAKEFTHTNDPTLALISAFLVFMLGFFMRPLGSLFFGKLGDKKGRKTSMVYSIILMA 94 P A +F T + +AF++ G+ +GKL D+ G K +++ II+ Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSI------GTAVYGKLSDQLGIKRLLLFGIIINC 90 Query: 95 LGSFLLALLPTKEIVGEWAFLFLLLARLLQGFSVGGE------YGVVATYLSELGKNGKK 148 GS + VG F L++AR +QG G VVA Y+ + + Sbjct: 91 FGSVIGF-------VGHSFFSLLIMARFIQG--AGAAAFPALVMVVVARYIPKENRGKAF 141 Query: 149 GFYGSFQYVTLVGGQLLAIFSLFIVENIYTHEQISAFAWRYLFALGGVLALFSLFLRNIM 208 G GS + +G + I I+ W YL + + + FL ++ Sbjct: 142 GLIGS---IVAMGEGVGPAIGGMIAHYIH---------WSYLLLIPMITIITVPFLMKLL 189 Query: 209 EETMDSQTTSKTTIKEKTQRGSLKELLNHKKALM-------IVFGLTMGGSLCFYTFTVY 261 + + +K + K ++ + T + Sbjct: 190 K-----------------KEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLS 232 Query: 262 LKIFLTNSSSFSPK-------ESSFIMLLALSYFIFLQPLCG---MLADKIKRTQMLMVF 311 IF+ + + ++ M+ L I + G M+ +K L Sbjct: 233 FLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTA 292 Query: 312 AIAGLIVTPVVFYGI 326 I +I+ P I Sbjct: 293 EIGSVIIFPGTMSVI 307
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 41.6 bits (97), Expect = 2e-05 Identities = 53/240 (22%), Positives = 77/240 (32%), Gaps = 30/240 (12%) Query: 169 FSPKKEGFENAPSDIQKKETKNDKEKENLKENPIDENHKTPNE--ESFLAIPTPYNTT-L 225 ++P+ E N D T N+ + + +E +E A TP TT Sbjct: 981 YNPEVEK-RNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTET 1039 Query: 226 NALEP--QEGLVQISSHPPTHYTIYPKRNRFNDLSN-PTNPTLKEI---KQETKEREPTP 279 A + V+ + T T + SN N E+ ETKE + T Sbjct: 1040 VAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTE 1099 Query: 280 TKETL-----------------APTMSKPATPKPIMPAPIMPTLAPNTEND---NKTENH 319 TKET P ++ +PK + P P END N E Sbjct: 1100 TKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQ 1159 Query: 320 KATNHPKKEENPQENAQEEMIKENIKEEEKETQDAPSFNPITPTSAKKPVMVKELSENKE 379 TN E P + + + + T ++ NP T A V S NK Sbjct: 1160 SQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKP 1219 Score = 35.4 bits (81), Expect = 0.001 Identities = 24/136 (17%), Positives = 48/136 (35%), Gaps = 3/136 (2%) Query: 249 PKRNRFNDLSNPTNPTLKEIKQETKEREPTPTKETLAPTMSKPATPKPIMPAPIMPTLAP 308 P+ + N + TN T Q P+ +E + P P P+ T+A Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAE 1042 Query: 309 NTENDNKTE--NHKATNHPKKEENPQENAQEEMIKENIKEEEKETQDAPSFNPITPTSAK 366 N++ ++KT N + + + +K N + E + + T K Sbjct: 1043 NSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKET-QTTETK 1101 Query: 367 KPVMVKELSENKEILD 382 + V++ + K + Sbjct: 1102 ETATVEKEEKAKVETE 1117
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 36.3 bits (83), Expect = 9e-05 Identities = 20/111 (18%), Positives = 39/111 (35%), Gaps = 7/111 (6%) Query: 46 KIKRKLNHFIGNILARTEVYKKLVAKYDDLTRKYDDLTRKYDDLTRKYDDL-------TR 98 ++ ++ +G T++Y+ + K D YD T+K K L + Sbjct: 124 QVSKEFQTALGEAQEATDLYEASIKKTDTAKSVYDAATKKLTQAQNKLQSLDPADPGYAQ 183 Query: 99 KYDDLTRKYDDLTRKYELLLAKETNIKETFWERRADSEKEAFFLEHFYLTS 149 + + + T E L + + +A +EK L F T+ Sbjct: 184 AEAAVEQAGKEATEAKEALDKATDATVKAGTDAKAKAEKADNILTKFQGTA 234
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 28.5 bits (63), Expect = 0.016 Identities = 20/52 (38%), Positives = 30/52 (57%), Gaps = 5/52 (9%) Query: 60 GELVPLEIVVETILSAIKSSDKGIILIDGYPRSVEQMQALDKELNAQNEVVL 111 G+L+ I VE LS I + D L+ P++ E++ ALDKEL A+ + L Sbjct: 127 GKLIAYPIAVEA-LSLIYNKD----LLPNPPKTWEEIPALDKELKAKGKSAL 173
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 54.8 bits (132), Expect = 1e-10 Identities = 24/110 (21%), Positives = 44/110 (40%), Gaps = 6/110 (5%) Query: 194 ILIAEDSLSALKTLEKIVQTLELRYLAFPNGKELLDYLYEKEHYQQVGVVITDLEMPVIS 253 IL+A+D + L + + N L ++ +V+TD+ MP + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAA----GDGDLVVTDVVMPDEN 61 Query: 254 GFEVLKTIKADSRTEHLPVIINSSMSSDSNRQLAQSLEADGFVVKSNILE 303 F++L IK LPV++ S+ ++ A A ++ K L Sbjct: 62 AFDLLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLT 109
>LCRVANTIGEN#Low calcium response V antigen signature. Length = 326 Score = 31.2 bits (70), Expect = 6e-04 Identities = 16/33 (48%), Positives = 20/33 (60%) Query: 16 KRKKLLTELAELEAEIKVSSERKSSFNISLSPS 48 R KL ELAEL AE+K+ S ++ N LS S Sbjct: 149 ARSKLREELAELTAELKIYSVIQAEINKHLSSS 181
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 274 bits (701), Expect = 2e-76 Identities = 104/397 (26%), Positives = 183/397 (46%), Gaps = 14/397 (3%) Query: 2820 AGNNSLMWLNALFVAKGGNPLFAPYYLQDNSTEHIVTLMKDITSALGMLSKSNLKNNSTD 2879 +G L L + + +A + S I + T+ L ++ K + Sbjct: 904 SGAQGRDLLQTLLI-DSHDAGYARTMIDATSANEITKQLNTATTTLNNIASLEHKTSGLQ 962 Query: 2880 VLQLNTYTQQMGRLAKLSSFASFDSTDFSERLSSLKNQRFADAIPNAMDVILKYSQRDKL 2939 L L+ RL LS + F++RL +LK+QRFA + +A +V+ +++ + + Sbjct: 963 TLSLSNAMILNSRLVNLSRRHTNHIDSFAKRLQALKDQRFAS-LESAAEVLYQFAPKYEK 1021 Query: 2940 KNNLWATGVGGVSFVENGTGTLYGINVGYDRFIKG---VIVGGYAAYGYSGFYER--ITS 2994 N+WA +GG S G +LYG + G D ++ G IVGG+ +YGYS F + + Sbjct: 1022 PTNVWANAIGGTSLNSGGNASLYGTSAGVDAYLNGEVEAIVGGFGSYGYSSFSNQANSLN 1081 Query: 2995 SKSDNVDVGLYARAFIKKSELTFSVNETWGDNKTQISSNDTLLSMINQSYQYSTWTTNAR 3054 S ++N + G+Y+R F + E F G +++ ++ LL +NQSY Y ++ R Sbjct: 1082 SGANNTNFGVYSRIFANQHEFDFEAQGALGSDQSSLNFKSALLRDLNQSYNYLAYSAATR 1141 Query: 3055 VNYGYDFMFKNKSVIVKPQIGLRYYYIGMTGLEGVMNNALYNQFKANADPSKKSVLMIDF 3114 +YGYDF F ++++KP +G+ Y ++G T + + S + + Sbjct: 1142 ASYGYDFAFFRNALVLKPSVGVSYNHLGSTNFKS----NSNQKVALKNGASSQHLFNASA 1197 Query: 3115 AFENRHYFNKNSYFYAIGGIGRDLLVRSMGDKLVRFIGDNILSYRKGELYNTFANITTGG 3174 E R+Y+ SYFY G+ ++ + V + + R NT A + GG Sbjct: 1198 NVEARYYYGDTSYFYMNAGVLQEFANFGSSNA-VSLNTFKVNATRNP--LNTHARVMMGG 1254 Query: 3175 EIRLFKSFYVNAGVGARFGLDYKMINITGNIGMRLAF 3211 E++L K ++N G L + + N+GMR +F Sbjct: 1255 ELKLAKEVFLNLGFVYLHNLISNIGHFASNLGMRYSF 1291
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 901 bits (2330), Expect = 0.0 Identities = 284/1038 (27%), Positives = 515/1038 (49%), Gaps = 40/1038 (3%) Query: 1 MYKTAINRPITTLMFALAIVFFGTMGFKKLSVALFPKIDLPTVVVTTTYPGASAEIIESK 60 M I RPI + A+ ++ G + +L VA +P I P V V+ YPGA A+ ++ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTDKIEEAVMGIDGIKKVTSTSSKNVSIVV-IEFELEKPNEEALNDVVNKISSVR-FDDS 118 VT IE+ + GID + ++STS S+ + + F+ + A V NK+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 119 NIKKPSINKFDTDSQAIISLFVSSSSVPAT--TLNDYAKKTIKPMLQKIDGVGGVQLNGF 176 +++ I+ + S ++ S + T ++DY +K L +++GVG VQL G Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG- 179 Query: 177 RERQIRIYADPTLMNKYNLTYADLFSTLKAENVEIDGGRIVNS------QRELSILVNAN 230 + +RI+ D L+NKY LT D+ + LK +N +I G++ + Q SI+ Sbjct: 180 AQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 231 SYSVADVEKIQV-----GNHVRLGDIAKIEIGLEEDNTFASFKDKPGVILEIQKIAGANE 285 + + K+ + G+ VRL D+A++E+G E N A KP L I+ GAN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 286 IEIVDRVYEALKHIQAISP-NYEIRPFLDTTGYIRTSIEDVKFDLVLGAILAVLVVFAFL 344 ++ + L +Q P ++ DTT +++ SI +V L +L LV++ FL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 345 RNGTITLVSAISIPISVMGTFALIQWMGFSLNMLTMVALTLAIGIIIDDAIVVIENIHK- 403 +N TL+ I++P+ ++GTFA++ G+S+N LTM + LAIG+++DDAIVV+EN+ + Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 404 KLEMGMNKRKASYEGVREIGFALVAISAMLLSVFVPIGNMKGIIGRFFQSFGITVALAIA 463 +E + ++A+ + + +I ALV I+ +L +VF+P+ G G ++ F IT+ A+A Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 464 LSYVVVVTIIPMVSSVVVNPRHS-------RFYVWSEPFFKALESRYTKLLQWVLNHKLI 516 LS +V + + P + + ++ P + F+ W F + YT + +L Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 517 IFIAVVLVFVGSLFVASKLGMEFMLKEDRGRFLVWLKAKPGVSIDY----MTQKSKIFQK 572 + L+ G + + +L F+ +ED+G FL ++ G + + + Q + + K Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 573 AIEKHAEVEFTTLQVGY-GTTQNPFKAKIFVQLKPLKERKKEHELGQFELMSALRKELKS 631 + + E FT + G QN FV LKP +ER E ++ + EL Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNA--GMAFVSLKPWEERNG-DENSAEAVIHRAKMELGK 656 Query: 632 MPEAKGLENINLSEVSLIGGGGDSSPFQTFVFSHSQEAVDKSVANLKKFLLESPELKGKI 691 + + + N+ + G ++ F + + D + L + + + Sbjct: 657 IRDGF-VIPFNMPAIV---ELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASL 712 Query: 692 EGYHTSTSESQPQLQLKILRQNANKYGVSAQTIGSVVSSAFSGTSQASVFKEDGKEYDMI 751 + E Q +L++ ++ A GVS I +S+A G + + F + G+ + Sbjct: 713 VSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGG-TYVNDFIDRGRVKKLY 771 Query: 752 IRVPDNKRVSVEDIKRLQVRNKYDKLMFLDALVEITETKSPSSISRYNRQRSVTVLAQPK 811 ++ R+ ED+ +L VR+ +++ A + RYN S+ + + Sbjct: 772 VQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAA 831 Query: 812 AGISLGEILTQVSKNAKEWLVEGANYRFTGEADNAKETNGEFLIALATAFVLIYMILAAL 871 G S G+ + + +N L G Y +TG + + + + +A +FV++++ LAAL Sbjct: 832 PGTSSGDAMALM-ENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAAL 890 Query: 872 YESILEPFIIMVTMPLSFSGAFFALGLVHQPLSMFSMIGLILLIGMVGKNATLLIDVANE 931 YES P +M+ +PL G A L +Q ++ M+GL+ IG+ KNA L+++ A + Sbjct: 891 YESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKD 950 Query: 932 -ERKKGLNIQEAILFAGKTRLRPILMTTIAMVCGMLPLALASGDGAAMKSPIGIAMSGGL 990 K+G + EA L A + RLRPILMT++A + G+LPLA+++G G+ ++ +GI + GG+ Sbjct: 951 LMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGM 1010 Query: 991 MISMVLSLLIVPVFYRLL 1008 + + +L++ VPVF+ ++ Sbjct: 1011 VSATLLAIFFVPVFFVVI 1028
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 51.0 bits (122), Expect = 1e-09 Identities = 22/69 (31%), Positives = 34/69 (49%) Query: 40 STGIVDSIKVTEGSVVKKGDVLLLLYNQDKQAQSDSTEQQLIFAKKQYQRYSKIGGAVDK 99 IV I V EG V+KGDVLL L +A + T+ L+ A+ + RY + +++ Sbjct: 103 ENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIEL 162 Query: 100 NTLESYEFN 108 N L + Sbjct: 163 NKLPELKLP 171 Score = 31.3 bits (71), Expect = 0.003 Identities = 21/152 (13%), Positives = 48/152 (31%), Gaps = 25/152 (16%) Query: 70 QAQSDSTEQQLIFAKKQYQR--YSKIGGAVDKNTLESYEFNYRRLESDYAYSIALLNKTI 127 +++ S +++ + ++ K+ D + + E ++ Sbjct: 279 ESEILSAKEEYQLVTQLFKNEILDKLRQTTDN--IGLLTLELAKNEER-------QQASV 329 Query: 128 LRAPFDGVIASKNIQVGEGVSANNTVLLRLVSHARKLVIE--FDSKYINAVKVG------ 179 +RAP + + GV L+ +V L + +K I + VG Sbjct: 330 IRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIK 389 Query: 180 -DTYTYSIDGDSNQHEAKITKIYP--TVDENT 208 + + Y+ G K+ I D+ Sbjct: 390 VEAFPYTRYGYL---VGKVKNINLDAIEDQRL 418
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.0 bits (65), Expect = 0.048 Identities = 16/113 (14%), Positives = 41/113 (36%), Gaps = 16/113 (14%) Query: 203 LARMIALQKKLEQIKTDIKRVTKLYDKGLTTIDDL-----QSLKAQGNLSEY--DILDMQ 255 LAR+ + K+ + + L K + + ++A L Y + ++ Sbjct: 220 LARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIE 279 Query: 256 FALEQNRLTLEYLTNLSVKNLKKTTIDVPNLQLRERQD-LVSLREQISALKYQ 307 + + + +T K +D +LR+ D + L +++ + + Sbjct: 280 SEILSAKEEYQLVTQ----LFKNEILD----KLRQTTDNIGLLTLELAKNEER 324
>FLAGELLIN#Flagellin signature. Length = 507 Score = 245 bits (627), Expect = 2e-77 Identities = 126/518 (24%), Positives = 209/518 (40%), Gaps = 22/518 (4%) Query: 2 AFRVNTNINAMNAHVQSALTQNALKTSLERLSSGLRINKAADDASGMTVADSLRSQANSL 61 A +NTN ++ +Q++L +++ERLSSGLRIN A DDA+G +A+ S L Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 GQAIANTNDGMGIIQVADKAMDEQLKILDTVKVKATQAAQDGQTTESRKAIQSDIVRLIQ 121 QA N NDG+ I Q + A++E L V+ + QA + K+IQ +I + ++ Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 GLDNIGNTTTYNGQALLSGQFTNKEFQVGAYSNQSIKASIGSTTSDKIGQVRI-ATGALI 180 +D + N T +NG +LS + QVGA ++I + +G G Sbjct: 121 EIDRVSNQTQFNGVKVLSQDN-QMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKE 179 Query: 181 TASGDISLTFKQVDGVNDVTLESVKISSSAGTGIGVLAEVINKNSNQTGVKAYASVITTS 240 GD+ +FK V G + + + K +G V ++ V A +TT Sbjct: 180 ATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTD 239 Query: 241 DVAVQSGSLSNLTLNGIHLGNIADIKKNDSDGRLVAAINAVTSETGVEAYTDQNGRLNLR 300 D N + K A A+ + + + + Sbjct: 240 DAE-----------NNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTID 288 Query: 301 SLDGRGIEIKTDSVSNGPSALTMVNGGQDLTKGSTNYGRLSLTRLDAKSINV------VS 354 + G K + NG V S + +N + Sbjct: 289 TKTGNDGNGKVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKT 348 Query: 355 ASDSQHLGFTAIGFGESQVAETTVNLRDVTGNFNANVKSASGANYNAVIASGNQSL---G 411 ++S L ++ TVN + T N + + +G + S Sbjct: 349 KNESAKLSDLEANNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINE 408 Query: 412 AGVTTLRGAMVVIDIAESAMKMLDKVRSDLGSVQNQMISTVNNISITQVNVKAAESQIRD 471 + + +SA+ +D VRS LG++QN+ S + N+ T N+ +A S+I D Sbjct: 409 DAAAAKKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIED 468 Query: 472 VDFAEESANFNKNNILAQSGSYAMSQANTVQQNILRLL 509 D+A E +N +K IL Q+G+ ++QAN V QN+L LL Sbjct: 469 ADYATEVSNMSKAQILQQAGTSVLAQANQVPQNVLSLL 506
>OMS28PORIN#OMS28 porin signature. Length = 257 Score = 28.2 bits (62), Expect = 0.025 Identities = 28/112 (25%), Positives = 54/112 (48%), Gaps = 11/112 (9%) Query: 27 NQTTELHHKNPYELLVATILSAQCTDARVNKITPKLFEKYPSVKDLAL-----ASLEEVK 81 N+ E+ K E A ++ + T +I + K P+ K+L L A +E+VK Sbjct: 132 NKVVEMSKKAVQETQKAVSVAGEATFLIEKQI---MLNKSPNNKELELTKEEFAKVEQVK 188 Query: 82 EIIKSVSYFNNKSKHLISMAQKVVRDFKGVIPSTQKELMSLDGVGQKTANVV 133 E + + +++ + AQKV+ G+ PS + ++++ V + +NVV Sbjct: 189 ETLMASERALDET---VQEAQKVLNMVNGLNPSNKDQVLAKKDVAKAISNVV 237
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 99 bits (249), Expect = 2e-30 Identities = 25/77 (32%), Positives = 47/77 (61%) Query: 34 LICDYKNLLDMEIVFSAELGSTQIPLLQILRFEKGSVIDLQKPAGESVDTFVNGRVIGKG 93 + D ++D+ + + ELG T++ + ++LR +GSV+ L AGE +D +NG +I +G Sbjct: 50 AMQDIDLIMDIPVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQG 109 Query: 94 EVMVFERNLAIRLNEIL 110 EV+V +R+ +I+ Sbjct: 110 EVVVVADKYGVRITDII 126
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 47.3 bits (112), Expect = 2e-08 Identities = 36/209 (17%), Positives = 71/209 (33%), Gaps = 14/209 (6%) Query: 104 PTPPTPPKPIEKPKPKPKPKPEPKKPNHKHKALKKVEKVEEKKVVEEKKEEKKIVEQKVE 163 P P +PI P P+ + VE E + + E +E +V +K + Sbjct: 41 IELPAPAQPISVTMVAPADLEPPQAV--QPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPK 98 Query: 164 QKKIEEKKPVKKEFDPNQLSFLPKEVAPPRQENNKGLDNQTRRDIDELYGEEFGDLGTAE 223 K + KPVKK P ++V P +N Sbjct: 99 PKPKPKPKPVKKVEQP------KRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTS 152 Query: 224 KDFIRNNLRDIGRITQKYLEYPQVAAYLGQDGTNAVEFYLHPNGDISDLKIIIGSEYKML 283 +++ +YP A L +G V+F + P+G + +++I+ M Sbjct: 153 VA------SGPRALSRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMF 206 Query: 284 DDNTLKTIQIAYKDYPRPKTKTLIRIRVR 312 + ++ + +P + ++ I + Sbjct: 207 EREVKNAMRRWRYEPGKPGSGIVVNILFK 235
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 30.9 bits (70), Expect = 0.002 Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 4/64 (6%) Query: 61 LQSYSVMLFFNLLLLIDILGFLPFSIYHHFMASLIFSALFCSSLFLSSPLLGMIALVALS 120 L Y F L+L+ +LPFS S + + +L PLL + AL+A++ Sbjct: 45 LSDYYFEHFSKLMLIPAEQSYLPFSQ----ALSYVVDNVLLEFFYLCFPLLTVAALMAIA 100 Query: 121 SSLL 124 S ++ Sbjct: 101 SHVV 104
>OMS28PORIN#OMS28 porin signature. Length = 257 Score = 29.8 bits (66), Expect = 0.019 Identities = 13/37 (35%), Positives = 25/37 (67%) Query: 309 EEDLLVSKKRLDKIYRLKQRVLGTLGGINPNFKKEIL 345 +E L+ S++ LD+ + Q+VL + G+NP+ K ++L Sbjct: 188 KETLMASERALDETVQEAQKVLNMVNGLNPSNKDQVL 224
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 2018 bits (5230), Expect = 0.0 Identities = 1184/1296 (91%), Positives = 1231/1296 (94%), Gaps = 5/1296 (0%) Query: 1 MELQQTHRKINRPLVSLALVGLLVSITPQKSHAAFFTTVIIPAIVGGIASGAAVGTVSGL 60 ME+QQTHRKINRPLVSLALVG LVSITPQ+SHAAFFTTVIIPAIVGGIA+GAAVGTVSGL Sbjct: 1 MEIQQTHRKINRPLVSLALVGALVSITPQQSHAAFFTTVIIPAIVGGIATGAAVGTVSGL 60 Query: 61 LGWGLKQAEEANKTPDKPDKVWRIQAGRGFNEFPNKEYDLYKSLLSSKIDGGWDWGNAAR 120 LGWGLKQAEEANKTPDKPDKVWRIQAG+GFNEFPNKEYDLYKSLLSSKIDGGWDWGNAAR Sbjct: 61 LGWGLKQAEEANKTPDKPDKVWRIQAGKGFNEFPNKEYDLYKSLLSSKIDGGWDWGNAAR 120 Query: 121 HYWVKGGQWNKLEVDMKDAVGTYKLSGLRNFTGGDLDVNMQKATLRLGQFNGNSFTSFKD 180 HYWVK GQWNKLEVDM++AVGTY LSGL NFTGGDLDVNMQKATLRLGQFNGNSFTS+KD Sbjct: 121 HYWVKDGQWNKLEVDMQNAVGTYNLSGLINFTGGDLDVNMQKATLRLGQFNGNSFTSYKD 180 Query: 181 SADRTTRVDFNAKNISIDNFLEINNRVGSGAGRKARSTVLTLQASEGITSGKNAEISLYD 240 SADRTTRVDFNAKNI IDNFLEINNRVGSGAGRKA STVLTLQASEGITS +NAEISLYD Sbjct: 181 SADRTTRVDFNAKNILIDNFLEINNRVGSGAGRKASSTVLTLQASEGITSRENAEISLYD 240 Query: 241 GATLNLASNSVKLMGNVWMGRLQYVGAYLAPSYSTINTSKVTGEVNFNHLTVGDRNAAQA 300 GATLNLASNSVKLMGNVWMGRLQYVGAYLAPSYSTINTSKVTGEVNFNHLTVGD NAAQA Sbjct: 241 GATLNLASNSVKLMGNVWMGRLQYVGAYLAPSYSTINTSKVTGEVNFNHLTVGDHNAAQA 300 Query: 301 GIIASKKTYIGTLDLWQSAGLNIIAPPEGGYKDKPNNTNSQSGAKNDKNESAKNDKQESS 360 GIIAS KT+IGTLDLWQSAGLNIIAPPEGGYKDKPN+ S + N AKNDKQESS Sbjct: 301 GIIASNKTHIGTLDLWQSAGLNIIAPPEGGYKDKPNDKPSNTTQNN-----AKNDKQESS 355 Query: 361 QNNSNTQVINPPNSGQKTEIQPTQVIDGPFAGAKDTVVNINRINTNADGTIKVGGYTASL 420 QNNSNTQVINPPNS QKTEIQPTQVIDGPFAG K+TVVNINRINTNADGTI+VGG+ ASL Sbjct: 356 QNNSNTQVINPPNSAQKTEIQPTQVIDGPFAGGKNTVVNINRINTNADGTIRVGGFKASL 415 Query: 421 TTNAANLNIGKGGINLSNQASGRSLLVENLTGNITVDGALMVNNQVGGYALAGSSANFEF 480 TTNAA+L+IGKGGINLSNQASGRSLLVENLTGNITVDG L VNNQVGGYALAGSSANFEF Sbjct: 416 TTNAAHLHIGKGGINLSNQASGRSLLVENLTGNITVDGPLRVNNQVGGYALAGSSANFEF 475 Query: 481 KAGVDTKNGTIAFNNNISLGRFVNLKASAHTVNFKDIDTGNGGFNTLDFSGVTNKVNINK 540 KAG DTKNGT FNN+ISLGRFVNLK AHT NFK IDTGNGGFNTLDFSGVTNKVNINK Sbjct: 476 KAGTDTKNGTATFNNDISLGRFVNLKVDAHTANFKGIDTGNGGFNTLDFSGVTNKVNINK 535 Query: 541 LITASTNVAVKNFNINELLVKTNGISVGEYTNFSEDIGNQSRINTVRLETGTRSIYSGGV 600 LITASTNVAVKNFNINEL+VKTNG+SVGEYT+FSEDIG+QSRINTVRLETGTRSIYSGGV Sbjct: 536 LITASTNVAVKNFNINELVVKTNGVSVGEYTHFSEDIGSQSRINTVRLETGTRSIYSGGV 595 Query: 601 KFKGGEKLVINDLYYAPWNYFDARNIKNVEITNKLAFGPQGSPWGTSKLMFNNLTLGPNA 660 KFKGGEKLVIND YYAPWNYFDARNIKNVEITNKLAFGPQGSPWGT+KLMFNNLTLG NA Sbjct: 596 KFKGGEKLVINDFYYAPWNYFDARNIKNVEITNKLAFGPQGSPWGTAKLMFNNLTLGQNA 655 Query: 661 VMDYSQFSNVTIQGNFINNQGTINYLVRGGNIETLSVGNAAVMSFNNDIDSATGFYKPLI 720 VMDYSQFSN+TIQG+F+NNQGTINYLVRGG + TL+VGNAA M F+N++DSATGFY+PL+ Sbjct: 656 VMDYSQFSNLTIQGDFVNNQGTINYLVRGGQVATLNVGNAAAMFFSNNVDSATGFYQPLM 715 Query: 721 KINSAQDLIKNKEHVLLKAKIIGYENASLGTNSISNANLIEQFNERLALYNNNNRMDTCV 780 KINSAQDLIKNKEHVLLKAKIIGY N S GT+SI+N NLIEQF ERLALYNNNNRMD CV Sbjct: 716 KINSAQDLIKNKEHVLLKAKIIGYGNVSAGTDSIANVNLIEQFKERLALYNNNNRMDICV 775 Query: 781 VRNTDDIKACGMAIGDQAMVNNPDNYKYLIGKAWKNIGISKTANGSKISVRYLGNATPAE 840 VRNTDDIKACG AIG+Q+MVNNP+NYKYL GKAWKNIGISKTANGSKISV YLGN+TP E Sbjct: 776 VRNTDDIKACGTAIGNQSMVNNPENYKYLEGKAWKNIGISKTANGSKISVHYLGNSTPTE 835 Query: 841 NGGNTTNLPTNATNNARFARYALIKNAPFAHYSATPNLVAINKHNFGTIESVFELANRSK 900 NGGNTTNLPTN TN RFA YALIKNAPFA YSATPNLVAIN+H+FGTIESVFELANRS Sbjct: 836 NGGNTTNLPTNTTNKVRFASYALIKNAPFARYSATPNLVAINQHDFGTIESVFELANRSN 895 Query: 901 DIDTLYANSGAQGRDLLQTLLIDSHNAGYARTMIDATSANEITKQLNTATDALNNIASLE 960 DIDTLYANSGAQGRDLLQTLLIDSH+AGYARTMIDATSANEITKQLNTAT LNNIASLE Sbjct: 896 DIDTLYANSGAQGRDLLQTLLIDSHDAGYARTMIDATSANEITKQLNTATTTLNNIASLE 955 Query: 961 HKTSGLQTLSLSNAMILNSRLVNLSRRHTNNIDSFARRLQALKDQRFASLESAAEVLYQF 1020 HKTSGLQTLSLSNAMILNSRLVNLSRRHTN+IDSFA+RLQALKDQRFASLESAAEVLYQF Sbjct: 956 HKTSGLQTLSLSNAMILNSRLVNLSRRHTNHIDSFAKRLQALKDQRFASLESAAEVLYQF 1015 Query: 1021 APKYEKPTNVWANAIGGASLNSGGNTSLYGTSAGVDAYLNGEVEAIVGGFGSYGYSSFSN 1080 APKYEKPTNVWANAIGG SLNSGGN SLYGTSAGVDAYLNGEVEAIVGGFGSYGYSSFSN Sbjct: 1016 APKYEKPTNVWANAIGGTSLNSGGNASLYGTSAGVDAYLNGEVEAIVGGFGSYGYSSFSN 1075 Query: 1081 QANSLNSGANNANFGVYSRIFANQHEFDFEAQGALGSDQSSLNFKSALLRDLNQSYNYLA 1140 QANSLNSGANN NFGVYSRIFANQHEFDFEAQGALGSDQSSLNFKSALLRDLNQSYNYLA Sbjct: 1076 QANSLNSGANNTNFGVYSRIFANQHEFDFEAQGALGSDQSSLNFKSALLRDLNQSYNYLA 1135 Query: 1141 YGAATRASYGYDFAFFRNALVLKPSVGVSYNHLGSTNFESNSTNKTALKNGASSQHLFNA 1200 Y AATRASYGYDFAFFRNALVLKPSVGVSYNHLGSTNF+SNS K ALKNGASSQHLFNA Sbjct: 1136 YSAATRASYGYDFAFFRNALVLKPSVGVSYNHLGSTNFKSNSNQKVALKNGASSQHLFNA 1195 Query: 1201 SANVEARYYYGDTSYFYMNAGVLQEFANFGSSHAVSLNTFKVNAARNPLNTHARVMMGGE 1260 SANVEARYYYGDTSYFYMNAGVLQEFANFGSS+AVSLNTFKVNA RNPLNTHARVMMGGE Sbjct: 1196 SANVEARYYYGDTSYFYMNAGVLQEFANFGSSNAVSLNTFKVNATRNPLNTHARVMMGGE 1255 Query: 1261 LKLAKEVFLNLGFIYLHNLISNAGYFASNLGMRYSF 1296 LKLAKEVFLNLGF+YLHNLISN G+FASNLGMRYSF Sbjct: 1256 LKLAKEVFLNLGFVYLHNLISNIGHFASNLGMRYSF 1291
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 91.3 bits (226), Expect = 6e-24 Identities = 60/245 (24%), Positives = 107/245 (43%), Gaps = 10/245 (4%) Query: 1 MGEKKESQKVAIITGASSGIGLECALMLLDQGYKVYALSRRATLCVALNHALC------E 54 M K K+A ITGA+ GIG A L QG + A+ + +L E Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE 60 Query: 55 SIDVDVSDSNALKEAFLNISAKEDHCDVLINSAGYGVFGSVEDTPIEEVKKQFSVNFFAL 114 + DV DS A+ E I + D+L+N AG G + EE + FSVN + Sbjct: 61 AFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGV 120 Query: 115 CEVVQFCLPLLKNKSYSKIFNLSSIAGRVSMLFLGHYSASKHALEAYSDALRLELKPFNI 174 + + ++ I + S V + Y++SK A ++ L LEL +NI Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNI 180 Query: 175 QVCLIEPGPVKSNWEKTAFENDERKDSLYALEVNAAKSFYSGV-YQKALSPKAVAQKIVF 233 + ++ PG +++ + + + ++ + + + ++F +G+ +K P +A ++F Sbjct: 181 RCNIVSPGSTETDMQWSLWADENGAEQVIK---GSLETFKTGIPLKKLAKPSDIADAVLF 237 Query: 234 LTMSQ 238 L Q Sbjct: 238 LVSGQ 242
>BINARYTOXINA#Clostridial binary toxin A signature. Length = 454 Score = 26.2 bits (57), Expect = 0.031 Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 1/71 (1%) Query: 10 YTQYSEKQLFNFLNSIKTKQKRALEKLKEIQAQKQ-RIKKALQFKALHLTENGYTIEEER 68 Y + EK FN + + + +LEK E++ Q ++ K FK + L E G E+ Sbjct: 134 YFESPEKFAFNKEIRTENQNEISLEKFNELKETIQDKLFKQDGFKDVSLYEPGNGDEKPT 193 Query: 69 EILARAKDTKN 79 +L K KN Sbjct: 194 PLLIHLKLPKN 204
>PF04605#Virulence-associated protein D (VapD) Length = 125 Score = 102 bits (256), Expect = 5e-32 Identities = 21/93 (22%), Positives = 45/93 (48%), Gaps = 3/93 (3%) Query: 3 ALAFDLKIEILKKEYGEPYNKAYDDLRQELELLGFEWTQGSVYVNYSKENTLAQVYKAIN 62 A+ FDL + L+K + + + Y +++ + GFE Q S Y + N +V + +N Sbjct: 7 AINFDLSTKSLEKYF-KDTREPYSLIKKFMLENGFEHRQYSGYTSKEPIN-ERRVIRIVN 64 Query: 63 KLS-QIEWFKKSVRDIRAFKVEDFSDFTEIVKS 94 KL+ + W + V++ ++ + E ++ Sbjct: 65 KLTKKFTWLGECVKEFDITEIGEQYSLKETIQD 97
>SECA#SecA protein signature. Length = 901 Score = 31.4 bits (71), Expect = 0.001 Identities = 15/76 (19%), Positives = 35/76 (46%), Gaps = 12/76 (15%) Query: 4 SPTKKDYTRYSEKQLFNLINQLEQKIKKMQNDRASFKEKMAKELEKRDQNFKDKIDALNG 63 S + R +++ N+IN +E +++K+ ++ EL+ + F+ +++ Sbjct: 12 SRNDRTLRRM--RKVVNIINAMEPEMEKLSDE----------ELKGKTAEFRARLEKGEV 59 Query: 64 LLQKISQAFDNKRDCC 79 L I +AF R+ Sbjct: 60 LENLIPEAFAVVREAS 75
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 129 bits (327), Expect = 2e-39 Identities = 53/119 (44%), Positives = 74/119 (62%), Gaps = 2/119 (1%) Query: 1 MRNIEARK-EKGDKQAKLAFEMCAYRIKKHIGAYMVALGRVDAIIFTGGLGENYSALRES 59 R++E + GDK+A+LA + AYR+KK IG+Y A+G VD I+FT G+GEN +RE Sbjct: 283 FRDLEDAAFKNGDKRAQLALNVFAYRVKKTIGSYAAAMGGVDVIVFTAGIGENGPEIREF 342 Query: 60 VCEGLENLGIALHKPTNDNPGNGLVDLSQPDSKVKVLRIPTDEELEIALQAKEIAKKLK 118 + +GLE LG L K N G +S DSKV V+ +PT+EE IA ++I + LK Sbjct: 343 ILDGLEFLGFKLDKEKNKVRGEE-AIISTADSKVNVMVVPTNEEYMIAKDTEKIVESLK 400
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 112 bits (283), Expect = 1e-33 Identities = 45/72 (62%), Positives = 56/72 (77%) Query: 2 HLGNGSSAAAIQKGKSVDTSMGLTPLEGLIMGTRCGDIDPTVVEYIAQCANKSLEEVMKI 61 HLGNGSS AA++ GKS+DTSMG TPLEGL MGTR G IDP+++ Y+ + N S EEV+ I Sbjct: 207 HLGNGSSIAAVKNGKSIDTSMGFTPLEGLAMGTRSGSIDPSIISYLMEKENISAEEVVNI 266 Query: 62 LNHESGLKGICG 73 LN +SG+ GI G Sbjct: 267 LNKKSGVYGISG 278
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 73.7 bits (181), Expect = 9e-19 Identities = 31/84 (36%), Positives = 50/84 (59%), Gaps = 6/84 (7%) Query: 1 MEILVLNLGSSSIKFKLFDMQENKPLASGLAEKIGEEIGQLKIKSHLHHNDQELKEKLVI 60 M+ILV+N GSSS+K++L + ++ LA GLAE+IG L N +++K K + Sbjct: 1 MKILVINCGSSSLKYQLIESKDGNVLAKGLAERIGINDSLLTHN----ANGEKIKIKKDM 56 Query: 61 KDHASGLLMIRESLT--KMGIIKD 82 KDH + ++ ++L G+IKD Sbjct: 57 KDHKDAIKLVLDALVNSDYGVIKD 80
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 46.6 bits (110), Expect = 3e-07 Identities = 42/230 (18%), Positives = 77/230 (33%), Gaps = 9/230 (3%) Query: 288 KRDKTLSKKKPEKTPTKTQITAQAATLENAPKIPLKTPPLMPLIGVNPPNDNAPTLLEKE 347 KR++T+ TP Q + N + P+ P P E Sbjct: 987 KRNQTVDTTNIT-TPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPS--------ETT 1037 Query: 348 EKTKEASENKEKTKETNNSAQNAQNAQASDKTSENKSTAPKETIKHFTQQLKQEIQEYKP 407 E E S+ + KT E N AQ + E KS T + Q E +E + Sbjct: 1038 ETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQT 1097 Query: 408 PMSRISMDLFPKELGKVEVIIQKVGKNLKVSVISHNNSLQTFLDNQQDLKNSLNALGFEG 467 ++ + + +E KVE + + V +T + + + + + Sbjct: 1098 TETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKE 1157 Query: 468 VDLSFSQDSSKEQPKEQLRESFKEQESTPLKENALKSYQENTDNENQETS 517 + + EQP ++ + ++ + N S EN +N T+ Sbjct: 1158 PQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATT 1207 Score = 35.4 bits (81), Expect = 6e-04 Identities = 47/271 (17%), Positives = 85/271 (31%), Gaps = 11/271 (4%) Query: 28 DTKNAPKSASKDFSKILNQKISKDKTAPKENPNA--LKATPKNSKEGAKKDAKELEKTPT 85 DT N + +++ E P ATP + E +++K+ KT Sbjct: 993 DTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVE 1052 Query: 86 PHHQHAQNLAKDQQAPTLKDLLNHKKTTASHEAQNETHENHETNPKTPNETLNKNEKKPN 145 + Q A + + N K T ++E E ET ET +++ Sbjct: 1053 KNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKA 1112 Query: 146 GVVSNAHQANLTHKNPLTPTNHANNAIKNPTAPTDTEKEPKTLKDIQTLSQKHDLNASNI 205 V + Q + ++P + ++ P A E +P T++ K + +N Sbjct: 1113 KVETEKTQEVPKVTSQVSPKQEQSETVQ-PQAEPARENDP-------TVNIKEPQSQTNT 1164 Query: 206 QATTPLEKKETPLNASDQLALKTTQTSINH-TLTKNDAKNTANLSSVLQSLEKKESHNKE 264 A T KET N + TT + N + +V K + Sbjct: 1165 TADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHR 1224 Query: 265 RTTPPSNEKKTPPLREALQMNAIKRDKTLSK 295 R+ P + + + S Sbjct: 1225 RSVRSVPHNVEPATTSSNDRSTVALCDLTST 1255
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 35.3 bits (81), Expect = 7e-04 Identities = 12/33 (36%), Positives = 20/33 (60%) Query: 2 NDTLLNAYSGIKTHQFGIDSLSNNIANVNTLGY 34 + + NA SG+ Q +++ SNNI++ N GY Sbjct: 1 SSLINNAMSGLNAAQAALNTASNNISSYNVAGY 33 Score = 33.0 bits (75), Expect = 0.004 Identities = 10/48 (20%), Positives = 20/48 (41%) Query: 557 IRHKYLETSNVNAGNALTNLILMQRGYSMNARAFGAGDDMIKEAISLK 604 + ++ S VN NL Q+ Y NA+ + + I+++ Sbjct: 499 LSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR 546
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 29.1 bits (65), Expect = 0.018 Identities = 12/33 (36%), Positives = 20/33 (60%) Query: 70 EPEVQILKDLKPDFIVVVACGKILPKEVLTIAP 102 EP +++L ++KP F+V A P+ + IAP Sbjct: 86 EPNLELLTEMKPSFMVWSAGYGPSPEMLARIAP 118
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 31.4 bits (71), Expect = 0.017 Identities = 31/203 (15%), Positives = 71/203 (34%), Gaps = 18/203 (8%) Query: 282 CQQKTITEEFKKQLESYFDTSYQESTETIKEKIKDYASRTAEVLERLDEIVKTEQNNL-- 339 K I E K + ++ + T + E +I + L Sbjct: 226 SNLKEIVEVCKDLFKEIQSNKFEFNCYTKNNSFVGFYCLNLMSKEDYKKIQYDSSSKLLE 285 Query: 340 ---QTKLDTEIFKRIIETLRSKINGNWQKMHDKSKEVSRSFKLESTKNEIKEIRDLIDTA 396 K ++ K L+ + N + K K ++ + K K+ K +L+ Sbjct: 286 NFYYAKDKSDRLKSKSSDLQKIVMNNINRCTKKDKILNNTLKKCEDKDIFKLYGELLTAN 345 Query: 397 NQQIANHNEMIK----DIKNQKKICVEQTWKFLVNEFKS---DIQEYNKKHCGLEKGIKK 449 + I+ +N + + ++E K+ ++Q Y KK+ L+K + Sbjct: 346 IYALKKGLSHIELANYYSENYDTVKIT------LDENKTPSQNVQSYYKKYNKLKKSEEA 399 Query: 450 FENEIRENEKKIEELENEIRELE 472 ++ +NE+++ L + + + Sbjct: 400 ANEQLLQNEEELNYLYSVLTNIN 422
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 43.3 bits (102), Expect = 1e-06 Identities = 28/195 (14%), Positives = 71/195 (36%), Gaps = 19/195 (9%) Query: 27 QIELENQSRF-LAQQKEFEKEVKEKRAQYQSHFKMLEQKEEALKEREKEQKAKFDDAVKQ 85 +++L ++ F ++E + + Q+ + QKE L ++ E+ + Sbjct: 167 ELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRY 226 Query: 86 ASALALQDERAKIIEEARKNAFLEQQKGLELLQKELDEKSKQVQELHQKEAEIERLKREN 145 + ++ R + + LE + + E EL ++++E+++ E Sbjct: 227 ENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQ-ENKYVEAV---NELRVYKSQLEQIESEI 282 Query: 146 NEAESRLKAENEKKLNEKLETERERIEKALHEKNELKFKQQEEQLEMLRNELKNAQRKAE 205 A+ + + NE L+ R+ + +L + + +A Sbjct: 283 LSAKEEYQLVTQLFKNEILDKLRQTTDNI---------GLLTLELAKNEERQQASVIRAP 333 Query: 206 LSSQQFQGEVQELAI 220 +S +VQ+L + Sbjct: 334 VS-----VKVQQLKV 343
>PF06438#Heme acquisition protein HasAp Length = 205 Score = 28.4 bits (63), Expect = 0.013 Identities = 10/43 (23%), Positives = 22/43 (51%) Query: 45 AFSYASSFKEYTIHSYEHAKNLLFLETIHTPEKAKELTNLGLF 87 + SY++++ +T+ Y + F + H P + + +N G F Sbjct: 4 SISYSTTYSGWTVADYLADWSAYFGDVNHRPGQVVDGSNTGGF 46
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 47.1 bits (112), Expect = 4e-08 Identities = 50/346 (14%), Positives = 105/346 (30%), Gaps = 54/346 (15%) Query: 5 ILITGAYGMVGQNTALYFKKNKPDV-----------TLLTPKKSELY-----------LL 42 L+TGA G +G + + + V L + EL L Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDLA 62 Query: 43 DKDNVQAYLKEYKPTGIIHCAGRVGGIVANMNDLSTYMVENLLMGLYLFSSALDLGVKKA 102 D++ + + R + ++ + Y NL L + ++ Sbjct: 63 DREGMTDLFASGHFERVFISPHR-LAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 103 INLASSCAYPKFAPNPLKESDLLNGSLEPTNEGYALAKLSVMKYCEYVSAEKDVFYKTLV 162 + +SS Y P D ++ + YA K + S + L Sbjct: 122 LYASSSSVYGLNRKMPFSTDDSVDHPVSL----YAATKKANELMAHTYSHLYGLPATGLR 177 Query: 163 PCNLYGEFDKFEEKIAHMIPGLIARMHTAKLKNEKEFAMWGDGTARREYLNAKDLARFIS 222 +YG + + P + T + K ++ G +R++ D+A I Sbjct: 178 FFTVYGPWGR---------PDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAII 228 Query: 223 LAYENIASIPS-----------------VMNVGSGVDYSIEEYYKKVAQVLDYKGAFVKD 265 + I + V N+G+ + +Y + + L + Sbjct: 229 RLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNML 288 Query: 266 LSKPVGMQQKLMDISK-QKALKWELEIPLEQGIKEAYEYYLKLLEV 310 +P + + D + + + E ++ G+K +Y +V Sbjct: 289 PLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDFYKV 334
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 87.9 bits (218), Expect = 1e-21 Identities = 46/180 (25%), Positives = 72/180 (40%), Gaps = 19/180 (10%) Query: 23 LITGVTGQDGSYLAEYLLNLGYEVHGLKRRSSSINTSRIDHLYEDLHSEHKRRFFLHYGD 82 L+TG G G ++++ LL G++V G+ + + S E L F H D Sbjct: 4 LVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQP---GFQFHKID 60 Query: 83 MTDSSNLIHLIATTKPTEIYNLAAQSHVKVSFETPEYTANADGIGTLRILEAMRILGLEK 142 + D + L A+ ++ + V+ S E P A+++ G L ILE R ++ Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ- 119 Query: 143 KTRFYQASTSELYGEVLETPQNENTPF-------NPRSPYAVAKMYAFYITKNYREAYNL 195 AS+S +YG N PF +P S YA K + Y Y L Sbjct: 120 --HLLYASSSSVYGL------NRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGL 171
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 31.7 bits (71), Expect = 0.004 Identities = 27/100 (27%), Positives = 48/100 (48%), Gaps = 19/100 (19%) Query: 162 YSNAFMKLQNKENTFEKALTNNKPLKEEKEEIKEKEEETITIGDNTNAMKIVKKDIQKGY 221 Y N M N++ + N + ++EEK++I + + + NA+K + + + Y Sbjct: 350 YINRVMMASNEQ------IINKEKIREEKQKIILDQAKALETQYVHNALK--RNPVPRNY 401 Query: 222 RALKSSQRKWYCLGICSKKSKLSLMPEEIFNDKQFTYFKF 261 ++ + K+SK +MP EIF+D FTYF F Sbjct: 402 NYYQAPE----------KRSK-HIMPSEIFDDGTFTYFGF 430
>PF04335#VirB8 type IV secretion protein Length = 227 Score = 133 bits (336), Expect = 1e-40 Identities = 38/202 (18%), Positives = 73/202 (36%), Gaps = 4/202 (1%) Query: 40 QSVFRLERNRLKIAYKLLGLMSFIAFILAIVLISVLPLQKTEHHF--VDFLNQDKHYAII 97 + K+A+ + G+ +A + + ++ PL+ E + VD + A Sbjct: 22 RDKLAAAERSKKLAWVVAGVAGALATAGVVAVAALTPLKTVEPYVITVDRNTGEASIAAK 81 Query: 98 QRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQN 157 D +I+ +EA+ + + YV RE + ++ V + S+ R+ KT N Sbjct: 82 LHGDATITYDEAVRKYFLATYVRYREGWIAAAREEYFDAVMVMSARPEQDRWSRFYKTDN 141 Query: 158 SIYAQSHLEREVHI-VNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIVLSYLFDTP 216 Q+ L + V I +A V + + + + + Y D Sbjct: 142 PQSPQNILANRTDVFVEIKRVSFLGGNVAQVYFTKESVTGSNST-KTDAVATIKYKVDGT 200 Query: 217 DFDYASMPKNPTGFKVTRYSIT 238 KNP G++V Y Sbjct: 201 PSKEVDRFKNPLGYQVESYRAD 222
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 78.2 bits (192), Expect = 2e-22 Identities = 19/77 (24%), Positives = 40/77 (51%), Gaps = 1/77 (1%) Query: 34 EQKGGEFSKLLKQSINELNNTQEQSDKALADMATGQIK-DLHQAAIAIGKAETSMKLMLE 92 Q F+ L +++ +++TQ + G+ L+ + KA SM++ ++ Sbjct: 27 PQPTISFAGQLHAALDRISDTQTAARTQAEKFTLGEPGVALNDVMTDMQKASVSMQMGIQ 86 Query: 93 VRNKAISAYKELLRTQI 109 VRNK ++AY+E++ Q+ Sbjct: 87 VRNKLVAAYQEVMSMQV 103
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 28.8 bits (64), Expect = 0.011 Identities = 10/38 (26%), Positives = 15/38 (39%) Query: 121 NVNAVVEMADLVEATRAYQANVAAFQSAKNMAQNAIGM 158 VN E +L + Y AN Q+A + I + Sbjct: 508 GVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 34.2 bits (78), Expect = 6e-04 Identities = 31/183 (16%), Positives = 74/183 (40%), Gaps = 10/183 (5%) Query: 106 NVELLKKLSPDLVVTFVGNPKAVEHAKKF--GISFLSFQEKTIAEVMEDID---AQAKAL 160 N+ELL ++ P +V G + E + G F K + A L Sbjct: 88 NLELLTEMKPSFMVWSAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNL 147 Query: 161 EIDASKKLAKMQETLDFIKERL-KDVKKKKGVELFHKAN--KISGHQALDSDILEKGGID 217 + A LA+ ++ + +K R K + + + G +L +IL++ GI Sbjct: 148 QSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYGIP 207 Query: 218 N-FGLKYVKFGRADVSVEKIVK-ENPEIIFIWWISPLTPEDVLNNPKFSTIKAIKNKQVY 275 N + + +G VS++++ ++ +++ + + ++ P + + ++ + Sbjct: 208 NAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNSKDMDALMATPLWQAMPFVRAGRFQ 267 Query: 276 KLP 278 ++P Sbjct: 268 RVP 270
>TYPE3IMPPROT#Type III secretion system inner membrane P protein family signature. Length = 224 Score = 29.4 bits (66), Expect = 0.029 Identities = 9/23 (39%), Positives = 12/23 (52%) Query: 4 LRYKLLLFVFIGFWGLLVLNLFI 26 KL+LFV + W LL L + Sbjct: 195 TPIKLVLFVALDGWTLLSKGLIL 217