>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 31.6 bits (71), Expect = 0.013 Identities = 23/109 (21%), Positives = 38/109 (34%), Gaps = 2/109 (1%) Query: 189 NDLKALERRAALKNKTSSSEFEAARSHLETLADQVKVLERALQTLTQEKASAQNAVEQAQ 248 N A E ++ +K T ++E A+S ET Q + +EKA + Q Sbjct: 1065 NREVAKEAKSNVKANTQTNE--VAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEV 1122 Query: 249 STLDKFANTAQRQGLEAYQQAAALRNADETTRARVQEIRASLAEAISDP 297 + + Q Q QA R D T + + + + P Sbjct: 1123 PKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQP 1171
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 157 bits (399), Expect = 2e-49 Identities = 118/256 (46%), Positives = 168/256 (65%), Gaps = 1/256 (0%) Query: 1 MFSVTYAQLNGWLTAFLWPFVRMLALVATAPVVGHAAVPVRVKIGIAAFMALVVAPTLGA 60 M VT Q WL + WP +R+LAL++TAP++ +VP RVK+G+A + +AP+L A Sbjct: 1 MLQVTSEQWLSWLNLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPA 60 Query: 61 MPDVTVFSAPGIWIVVTQFLIGVALGFTMQLVFAAVEAAGDFIGLSMGLGFATFFDPHSN 120 DV VFS +W+ V Q LIG+ALGFTMQ FAAV AG+ IGL MGL FATF DP S+ Sbjct: 61 -NDVPVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASH 119 Query: 121 GATPVMGRFLNAIAMLAFLAVDGHLQVFAALAASFQTLPVSGDLLHAPGWRTLAAFGATV 180 PV+ R ++ +A+L FL +GHL + + L +F TLP+ G+ L++ + L G+ + Sbjct: 120 LNMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLI 179 Query: 181 FEMGLLLALPVVAALLIANLALGILNRAAPQIGIFQIGFPVTMLVGLLLVQLMIPNLVPF 240 F GL+LALP++ LL NLALG+LNR APQ+ IF IGFP+T+ VG+ L+ ++P + PF Sbjct: 180 FLNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPF 239 Query: 241 VSHLFDMGLDTMGRVL 256 HLF + + ++ Sbjct: 240 CEHLFSEIFNLLADII 255
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 65.9 bits (161), Expect = 4e-18 Identities = 28/85 (32%), Positives = 44/85 (51%) Query: 4 EQVMTLAHQAMMVGLLLAAPLLLVALAVGLVVSLFQAATQINESTLSFIPKLLAVAATLV 63 + ++ ++A+ + L+L+ +VA +GL+V LFQ TQ+ E TL F KLL V L Sbjct: 2 DDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLF 61 Query: 64 IAGPWMLTTMLDYLRQTLLHVATLG 88 + W +L Y RQ + G Sbjct: 62 LLSGWYGEVLLSYGRQVIFLALAKG 86
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 290 bits (745), Expect = e-102 Identities = 153/247 (61%), Positives = 196/247 (79%), Gaps = 4/247 (1%) Query: 6 LRRAARFAPALILGLAPALACAQAAGLPAFNTSPGPNGGTTYSLSVQTMLLLTMLSFLPA 65 +RR AP L+ + P A LP + P P GG ++SL VQT++ +T L+F+PA Sbjct: 1 MRRLLSVAPVLLWLITPLAF----AQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPA 56 Query: 66 MLLMMTSFTRIIIVLSLLRQALGTATTPPNQVLVGLAMFLTFFVMSPVLDRAYADGYKPF 125 +LLMMTSFTRIIIV LLR ALGT + PPNQVL+GLA+FLTFF+MSPV+D+ Y D Y+PF Sbjct: 57 ILLMMTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPF 116 Query: 126 SDGSMPMEQAVRRGVAPFKTFMLKQTRETDLALFAKISKAAPMQGPEDVPLSLLVPAFVT 185 S+ + M++A+ +G P + FML+QTRE DL LFA+++ P+QGPE VP+ +L+PA+VT Sbjct: 117 SEEKISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVT 176 Query: 186 SELKTGFQIGFTIFIPFLIIDMVVASVLMSMGMMMVSPSTVSLPFKLMLFVLVDGWQLLI 245 SELKT FQIGFTIFIPFLIID+V+ASVLM++GMMMV P+T++LPFKLMLFVLVDGWQLL+ Sbjct: 177 SELKTAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLV 236 Query: 246 GSLAQSF 252 GSLAQSF Sbjct: 237 GSLAQSF 243
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 134 bits (339), Expect = 2e-43 Identities = 76/132 (57%), Positives = 99/132 (75%), Gaps = 3/132 (2%) Query: 33 AAEDEQGLDD-WAAALAEQNLQPVQAGATGAGVFQPLSKAAASSTHNDIEMILDIPVKMT 91 + E+ LDD WA AL EQ ++ A VFQ L S DI++I+DIPVK+T Sbjct: 8 SDENTGALDDLWADALNEQKATTTKSAADA--VFQQLGGGDVSGAMQDIDLIMDIPVKLT 65 Query: 92 VELGRTKIAIRNLLQLAQGSVVELDGMAGEPMDVLVNGCLIAQGEVVVVNDKFGIRLTDI 151 VELGRT++ I+ LL+L QGSVV LDG+AGEP+D+L+NG LIAQGEVVVV DK+G+R+TDI Sbjct: 66 VELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGVRITDI 125 Query: 152 ITPAERIRKLNR 163 ITP+ER+R+L+R Sbjct: 126 ITPSERMRRLSR 137
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 271 bits (695), Expect = 8e-92 Identities = 80/324 (24%), Positives = 158/324 (48%), Gaps = 10/324 (3%) Query: 5 EFMSQEEVDALLKGV-TGETDTVDEQ--RDLSGVRPYNIATQERIVRGRMPGLEIINDRF 61 E +SQ+E+D LL + +G+ D + D + Y+ ++ + +M L ++++ F Sbjct: 3 EVLSQDEIDQLLTAISSGDASIEDARPISDTRKITLYDFRRPDKFSKEQMRTLSLMHETF 62 Query: 62 ARLLRIGIFNFMRRTAEISVSQVKVQKYSEFTRNLPIPTNLNLVHVKPLRGTSLFVFDPN 121 ARL + +R + V+ V Y EF R++P P+ L ++ + PL+G ++ DP+ Sbjct: 63 ARLTTTSLSAQLRSMVHVHVASVDQLTYEEFIRSIPTPSTLAVITMDPLKGNAVLEVDPS 122 Query: 122 LVFFVVDNLFGGDGRFHTRVEGRDFTATEQRIIGKLLNLVFEHYATAWKSVRPLQFEFVR 181 + F ++D LFGG G+ RD T E ++ ++ + + +W V L+ + Sbjct: 123 ITFSIIDRLFGGTGQAAKVQ--RDLTDIENSVMEGVIVRILANVRESWTQVIDLRPRLGQ 180 Query: 182 SEMHTQFANVATPNEIVIVTQFSIEFGPTGGTLHICMPYSMIEPIRDVLSSPIQGEAL-- 239 E + QFA + P+E+V++ + G G ++ C+PY IEPI LSS ++ Sbjct: 181 IETNPQFAQIVPPSEMVVLVTLETKVGEEEGMMNFCIPYITIEPIISKLSSQFWFSSVRR 240 Query: 240 EVDRRWVRVLSQQVQSAEVELSANLAEIPSTFEKILNLRAGDVLPLE---IEDTITAKVD 296 +++ VL ++ + ++++ A + + + IL LR GD++ L + D + Sbjct: 241 SSTTQYMGVLRDKLSTVDMDVVAEVGSLRLSVRDILGLRVGDIIRLHDTHVGDPFVLSIG 300 Query: 297 GVPVMECGYGIFNGQYALRVQKMI 320 C G+ + A ++ + I Sbjct: 301 NRKKFLCQPGVVGKKIAAQILERI 324
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 120 bits (302), Expect = 2e-31 Identities = 83/398 (20%), Positives = 161/398 (40%), Gaps = 16/398 (4%) Query: 30 LALGTFMEVLDTSIANVAVPTISGSLGVATSEGTWVISSYSVASAIAVPLTGWLARRVGE 89 L + +F VL+ + NV++P I+ + WV +++ + +I + G L+ ++G Sbjct: 19 LCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGI 78 Query: 90 VRLFTLSVLAFTIASALCGLA-SNFETLIAFRLLQGLVSGPMVPLSQTILMRSYPPAKRG 148 RL ++ S + + S F LI R +QG + L ++ R P RG Sbjct: 79 KRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRG 138 Query: 149 LALGLWAMTVIVAPIFGPLLGGWISDNYTWPWIFYINLPIGIFSAACAYFLLRGRETKTS 208 A GL V + GP +GG I+ W ++ I + I L ++ Sbjct: 139 KAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLL---KKEVRI 195 Query: 209 RQRIDAVGLALLVIGVSCLQMMLDLGKDRDWFNSTFIVALALIAVVSLAFMLVWEATEKE 268 + D G+ L+ +G+ + F +++ ++ +++V+S + + Sbjct: 196 KGHFDIKGIILMSVGIVFFML----------FTTSYSISFLIVSVLSFLIFVKHIRKVTD 245 Query: 269 PVVDLSLFKDRNFALGAMIISFGFMAFFGSVVIFPLWLQTVMGYTAGKAGLATA-PVGLL 327 P VD L K+ F +G + F G V + P ++ V + + G P + Sbjct: 246 PFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMS 305 Query: 328 ALVLSPLIGRNMHRLDLRMVASFAFIVFAGVSVWNSTFTLDVPFNHVILPRLVQGIGVAC 387 ++ + G + R V + + F VS ++F L+ + + + G++ Sbjct: 306 VIIFGYIGGILVDRRGPLYVLNIG-VTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSF 364 Query: 388 FFVPMTTITLSSISDERLASASGLSNFLRTLSGAIGTA 425 ++TI SS+ + + L NF LS G A Sbjct: 365 TKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIA 402
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 36.8 bits (85), Expect = 2e-05 Identities = 18/62 (29%), Positives = 32/62 (51%), Gaps = 5/62 (8%) Query: 11 SRRVRGFTLIELMIAIAILAVVAILAWRGLDQIMRGRDK--VASAMEDERVFAQMFDQMR 68 + + RGFTL+E+M+ I I+ V+A L + +M ++K A+ D D + Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLV---VPNLMGNKEKADKQKAVSDIVALENALDMYK 60 Query: 69 ID 70 +D Sbjct: 61 LD 62
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 26.8 bits (59), Expect = 0.035 Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 5/85 (5%) Query: 5 ATIARPYAEALFRVAEGGDIAAWSTLVQELAQVARLPEVLSVASSPKVTRTQVVELLLAA 64 AT + A+A+F+ GGD+ S +Q++ + +P L+V TR + ELL Sbjct: 28 ATTTKSAADAVFQQLGGGDV---SGAMQDIDLIMDIPVKLTVELGR--TRMTIKELLRLT 82 Query: 65 VKSPVAAGAEAKNFVQMLVDNHRIA 89 S VA A + +L++ + IA Sbjct: 83 QGSVVALDGLAGEPLDILINGYLIA 107
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 84.9 bits (210), Expect = 1e-22 Identities = 36/120 (30%), Positives = 61/120 (50%), Gaps = 2/120 (1%) Query: 4 TILAIDDSATMRALLQATLAQAGYDVTVAPDGEAGFDMAATVPYDLVLTDQNMPRRSGLE 63 TIL DD A +R +L L++AGYDV + + + A DLV+TD MP + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 64 VIAALRKLSAYADTPILVLTTEGSDAFKDAAREAGATGWIEKPIDPAVLVDLVATLSEQT 123 ++ ++K A D P+LV++ + + A E GA ++ KP D L+ ++ + Sbjct: 65 LLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122
>PF06580#Sensor histidine kinase Length = 349 Score = 46.8 bits (111), Expect = 2e-07 Identities = 21/151 (13%), Positives = 49/151 (32%), Gaps = 52/151 (34%) Query: 445 ELDKSLIERIIDPLT--HLVRNSLDHGIETVDKRIAAGKDAVGQLVLSAAHHGGNIVIEV 502 +++ ++++ + P+ LV N + HGI G+++L G + +EV Sbjct: 245 QINPAIMDVQVPPMLVQTLVENGIKHGIA--------QLPQGGKILLKGTKDNGTVTLEV 296 Query: 503 SDDGGGLNRERILAKAAKQGMQVSDNISDDEVWQLIFAPGFSTAETVTDVSGRGVGMDVV 562 + G + G G+ V Sbjct: 297 ENTGSLALKNTK--------------------------------------ESTGTGLQNV 318 Query: 563 KRNIQSMGG---HVEISSQAGRGTTTRIVLP 590 + +Q + G +++S + G +++P Sbjct: 319 RERLQMLYGTEAQIKLSEKQG-KVNAMVLIP 348
>OMS28PORIN#OMS28 porin signature. Length = 257 Score = 30.5 bits (68), Expect = 0.017 Identities = 43/197 (21%), Positives = 86/197 (43%), Gaps = 14/197 (7%) Query: 296 EQAASLQETASSMEQLTGTVRQNAENARQASQLAVNASDIATQGGDVVGQVVSTMQDIAA 355 +Q + + ++ ++T V E R++S V ++D A VG + S M D+A Sbjct: 51 DQKDQVNQALDTINKVTEDVSSKLEGVRESSLELVESND-AGVVKKFVGSM-SLMSDVAK 108 Query: 356 SS---GKVVDIIGTIEGIAFQTNILALNAAVEAARAGEQGRGFAV-VAGEVRSLAQR--- 408 + + I+ G+ + N VE ++ Q AV VAGE L ++ Sbjct: 109 GTVVASQEATIVAKCSGMVAE----GANKVVEMSKKAVQETQKAVSVAGEATFLIEKQIM 164 Query: 409 -SASAAKEIKQLIGDSAEKVESGSALVARAGSTMDEIVQAVRRVTDIMGEISAASDEQST 467 + S + +L + KVE + + +DE VQ ++V +++ ++ ++ +Q Sbjct: 165 LNKSPNNKELELTKEEFAKVEQVKETLMASERALDETVQEAQKVLNMVNGLNPSNKDQVL 224 Query: 468 GIEQVNRAVGQMDSVTQ 484 + V +A+ + V Q Sbjct: 225 AKKDVAKAISNVVKVAQ 241
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 56.8 bits (137), Expect = 6e-11 Identities = 25/189 (13%), Positives = 60/189 (31%), Gaps = 22/189 (11%) Query: 9 LKIDRRPIAPAPRRRRWVRYAVAAVLVIIAIAAALALTGRPTVDTTSVTSAYPYQNDTQL 68 L++ P++ PR + + I+++ + + Sbjct: 46 LELIETPVSRRPRLVAYFIMGFLVIAFILSVLGQV---------------------EIVA 84 Query: 69 NATGYVVPQ-RKAAVASKGQGRVEWLGVLEGTRVKKGEIIARLESRDVEASLAQARAQVL 127 A G + R + V+ + V EG V+KG+++ +L + EA + ++ +L Sbjct: 85 TANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLL 144 Query: 128 VSRANLGVAQAELKDAQIALRRTAVLAPKGAVPAAQLDTDTARANKARATLGSDQAAIAS 187 +R Q + ++ L + + + + + Q Sbjct: 145 QARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQ 204 Query: 188 AEANAQAAQ 196 E N + Sbjct: 205 KELNLDKKR 213 Score = 51.0 bits (122), Expect = 4e-09 Identities = 44/220 (20%), Positives = 72/220 (32%), Gaps = 64/220 (29%) Query: 116 EASLAQARAQVLVSRANLGVAQAELKDAQIALRRTAVLAPKGAVPAAQLDTDTARANKAR 175 E +L + RA+ L A + + + + L + L K A+ + + +A Sbjct: 206 ELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAV 265 Query: 176 ATLGSDQAAIASAEANAQAAQVAVDQ---------------------------------- 201 L ++ + E+ +A+ Sbjct: 266 NELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQ 325 Query: 202 --TVIRAPFDGIV--LAKHANVGDNITPFSSASDSKGAVVTIA--------DMDTLEVEA 249 +VIRAP V L H ++G VVT A + DTLEV A Sbjct: 326 QASVIRAPVSVKVQQLKVH---------------TEGGVVTTAETLMVIVPEDDTLEVTA 370 Query: 250 DVAESNIAKIRAEQPCEIQLDALPDMRF---AGRVSRIVP 286 V +I I Q I+++A P R+ G+V I Sbjct: 371 LVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINL 410
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 68.5 bits (167), Expect = 7e-15 Identities = 33/183 (18%), Positives = 63/183 (34%), Gaps = 38/183 (20%) Query: 116 NLGSGVIVSPEGYILTNQHVVDGADQIEVALA------------DGRTATAKVIGSDPET 163 + SGV+V +LTN+HVVD AL +G ++ E Sbjct: 102 FIASGVVVGK-DTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEG 160 Query: 164 DLAVLKIN--------MTNLPTITLGRSDQSRVGDVVLAIGNPFGVGQTVTMGIISALGR 215 DLA++K + + T+ + +++V + G P ++ + Sbjct: 161 DLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGD-------KPVATMWE 213 Query: 216 NHLGINTFEN-FIQTDAPINPGNSGGALVDVNGNLLGINTAIYSRSGGSLGIGFAIPVST 274 + I + +Q D GNSG + + ++GI+ G+ + Sbjct: 214 SKGKITYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHWG---------GVPNEFNGAV 264 Query: 275 ART 277 Sbjct: 265 FIN 267
>PF05860#haemagglutination activity domain. Length = 117 Score = 66.4 bits (162), Expect = 1e-14 Identities = 25/134 (18%), Positives = 47/134 (35%), Gaps = 21/134 (15%) Query: 39 ITPDRSGPTHPVVGVSASGVPLVNITAPKNGVSLNNFTQYNVGTKGAVLVNSGQNLQTQL 98 ITPD + P + + + ++ ++F +++V T G Sbjct: 3 ITPDTTLPINSNI-TTEGNTRIIERGTQAGSNLFHSFQEFSVPTSGTAF----------- 50 Query: 99 AGWVQGNPFLGNNAARVIVNQVTSGNPSQLLGPTEIAGNRANLVIANPAGITCAGCGFLN 158 F + I+++VT G+ S + G A ANL + NP GI L+ Sbjct: 51 --------FNNPTNIQNIISRVTGGSVSNIDGLIR-ANATANLFLINPNGIIFGQNARLD 101 Query: 159 VPRVTLTTGVPTFN 172 + + + Sbjct: 102 IGGSFVGSTANRLK 115
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 38.0 bits (88), Expect = 3e-04 Identities = 30/142 (21%), Positives = 55/142 (38%), Gaps = 25/142 (17%) Query: 915 SPEAAQAAASGQLASQLQGMAPAATTA---AMGLVSGGSAGAALGGLASSALPAAASALG 971 + +AAA +L +++ G + A G S AA GL +SA+ A S L Sbjct: 263 ADTRTKAAAGVELTTKVLGNVGKGISQYIIAQRAAQGLSTSAAAAGLIASAVTLAISPLS 322 Query: 972 GAGAASALQTASSLSGAAKQV-----------------AGMVQAARQG---GLAALAAPA 1011 A + A+ + +++ G + A+ LA++++ Sbjct: 323 FLSIADKFKRANKIEEYSQRFKKLGYDGDSLLAAFHKETGAIDASLTTISTVLASVSSGI 382 Query: 1012 ANAASGALQGALPG--VAGIAG 1031 + AA+ +L GA V + G Sbjct: 383 SAAATTSLVGAPVSALVGAVTG 404
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 93.8 bits (233), Expect = 5e-24 Identities = 37/112 (33%), Positives = 59/112 (52%), Gaps = 11/112 (9%) Query: 214 FETGSATLTPQGRQILDQMAAALS--KLQNRTVDIIGHTDNSGNRTSNIALSQARADAVK 271 F ATL P+G+ LDQ+ + LS ++ +V ++G+TD G+ N LS+ RA +V Sbjct: 223 FNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSVV 282 Query: 272 GYLITKSIPPQQMTTTGVGPDQPIAPNDTAEGRAR---------NRRIEFRV 314 YLI+K IP +++ G+G P+ N + R +RR+E V Sbjct: 283 DYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEV 334
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 37.5 bits (87), Expect = 1e-05 Identities = 24/109 (22%), Positives = 41/109 (37%), Gaps = 6/109 (5%) Query: 3 RRADRLFQIAELLRGRRLTTAQQLADWL-----SVSPRTVYRDVRDLQLSGVPIEGEAGI 57 + R +I E++ + T +L D L +V+ TV RD+++L L VP + Sbjct: 2 NKGQRHIKIREIITANEIETQDELVDILKKDGYNVTQATVSRDIKELHLVKVPTNNGSYK 61 Query: 58 GYRLNRNASLPPLTFTAEELAALAVGARMLETWGGARFAGGARSALAKI 106 Y L + PL+ L V + G A+ + Sbjct: 62 -YSLPADQRFNPLSKLKRSLMDAFVKIDSASHLIVLKTMPGNAQAIGAL 109
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 95.8 bits (238), Expect = 3e-26 Identities = 25/105 (23%), Positives = 48/105 (45%), Gaps = 5/105 (4%) Query: 64 SIYFDFDSYSVKDEYQPLMQQHAQYLKSHPQRH--VLIQGNTDERGTSEYNLALGQKRAE 121 + F+F+ ++K E Q + Q L + + V++ G TD G+ YN L ++RA+ Sbjct: 220 DVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQ 279 Query: 122 AVRRAMALLGVNDSQMEAVSLGKEKPQASGHDEASWAQNRRADLV 166 +V + G+ ++ A +G+ P +RA L+ Sbjct: 280 SVVDYLISKGIPADKISARGMGESNPVTG---NTCDNVKQRAALI 321
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 56.6 bits (136), Expect = 9e-11 Identities = 30/196 (15%), Positives = 70/196 (35%), Gaps = 13/196 (6%) Query: 49 STPAGAEAELWTEVPDVPAPRPVVTPTPPAKLAPPPPPVRDEQADIALQQKKRQQEAAAR 108 +T + +VP VP+ + A + PP P E + + K++ + + Sbjct: 994 TTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEK 1053 Query: 109 EALLEQQRRAQQLKAQQ----EEARREQLAAQQAAALAAQKAAERDKQKQADKLKQQQLV 164 ++ A + AQ +EA+ A Q +A + ++ Q K Sbjct: 1054 -----NEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEK 1108 Query: 165 E-QQKLEQQKAQQQKQQQQKQAQLEAQEAAKAKADAAAKAKAESQAKAKAEAAARAKADA 223 E + K+E ++ ++ + +Q+ ++ A+ E+ + Sbjct: 1109 EEKAKVE---TEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTT 1165 Query: 224 AAKAKLDRERNARLAQ 239 A + +E ++ + Q Sbjct: 1166 ADTEQPAKETSSNVEQ 1181 Score = 42.7 bits (100), Expect = 2e-06 Identities = 27/150 (18%), Positives = 52/150 (34%), Gaps = 12/150 (8%) Query: 97 QQKKRQQEAAAREALLEQQRRAQQLKAQQEEARREQLAAQQAAALAAQKAAERDKQKQAD 156 + +KR Q +A E++A A + A + + Sbjct: 984 EVEKRNQTVDTTNITTPNNIQADVPSVPS---NNEEIARVDEAPVPPPAPATPSETTETV 1040 Query: 157 KLKQQQLVEQQKLEQQKAQQQKQQQQKQAQLEAQEAAKAKADAAAKAK-----AESQAKA 211 +Q + + +Q A + Q ++ A EA+ KA A+ E+Q Sbjct: 1041 AENSKQESKTVEKNEQDATETTAQNREVA-KEAKSNVKANTQTNEVAQSGSETKETQTTE 1099 Query: 212 KAEAAARAKADAAAKAKLDRERNARLAQMQ 241 E A K + KAK++ E+ + ++ Sbjct: 1100 TKETATVEKEE---KAKVETEKTQEVPKVT 1126
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 85.9 bits (212), Expect = 3e-22 Identities = 51/180 (28%), Positives = 84/180 (46%), Gaps = 4/180 (2%) Query: 2 IVFVTGASAGFGAAIARAFVKGGHRVVATARRKDRLDAL-AAELGDALLP--FELDVRDR 58 I F+TGA+ G G A+AR G + A ++L+ + ++ +A F DVRD Sbjct: 10 IAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDS 69 Query: 59 TAVEAVPAVLPAEFAALDVLVNNAGLALGVEPAHKASLDEWQTMIDTNCSGLVTVTHALL 118 A++ + A + E +D+LVN AG+ L H S +EW+ N +G+ + ++ Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGV-LRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 119 PGMIARGRGHIFNLGSVAGTYPYPGGNVYGATKAFVRQFSLNLRADLIGTPLRVTDIEPG 178 M+ R G I +GS P Y ++KA F+ L +L +R + PG Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 27.2 bits (60), Expect = 0.026 Identities = 10/23 (43%), Positives = 14/23 (60%) Query: 17 GFTLVELMVAIALAGSIGLFAAP 39 GFTL+E+MV I + G + P Sbjct: 9 GFTLLEIMVVIVIIGVLASLVVP 31
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 28.5 bits (63), Expect = 0.011 Identities = 31/104 (29%), Positives = 43/104 (41%), Gaps = 7/104 (6%) Query: 7 SMRGTSLLEAVLAVALLAVVMLAVAGSQLAMTRAQRATIWRERALWLADARIERRYA-AA 65 ++ A AV++L L + G + RA + + L A I R A A Sbjct: 207 NVTAVPASGAPAAVSVLGASELTLDGGHITGGRAAGVAAMQGAVVHLQRATIRRGDAPAG 266 Query: 66 GADDGIAALVVALLPGGAMTLDHGPGGVRYVIVGWRGAGATVST 109 GA G A PGGA+ GPGG V+ GW G + S+ Sbjct: 267 GAVPGGAV------PGGAVPGGFGPGGFGPVLDGWYGVDVSGSS 304
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 38.7 bits (90), Expect = 1e-06 Identities = 16/55 (29%), Positives = 29/55 (52%) Query: 7 MRRVAAFTLLELMIVLAIVAVLAGWGIPSYREHVARMHRASAVAALYRAAQYLEM 61 + FTLLE+M+V+ I+ VLA +P+ + + + AV+ + L+M Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDM 58
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 30.5 bits (69), Expect = 0.016 Identities = 21/84 (25%), Positives = 33/84 (39%), Gaps = 21/84 (25%) Query: 19 RQADVFVADGKIAALG-----------TTPAGFNAEKTIDASGLIVAPGLVDLCARLREP 67 +AD+ + DG+IAA+G T G E I G IV G +D P Sbjct: 84 VKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTE-VIAGEGKIVTAGGMDSHIHFICP 142 Query: 68 GYEHKATLASEMAAAVAGGVTTLV 91 ++ A+ G+T ++ Sbjct: 143 ---------QQIEEALMSGLTCML 157
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 178 bits (454), Expect = 1e-55 Identities = 90/350 (25%), Positives = 136/350 (38%), Gaps = 43/350 (12%) Query: 2 ILVTGGAGFIGANFVLDWLRQSDEAVLNVDKLT--YAGNLRTL-QSLDGSPKHVFVRADI 58 LVTG AGFIG + L + V+ +D L Y +L+ L P F + D+ Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGHQ-VVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 59 CDRAALDALFAEYQPRAVLHFAAESHVDRSIHGPAEFVQTNVVGTFTLLEAARTYWNGLN 118 DR + LFA V V S+ P + +N+ G +LE R Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHN----- 116 Query: 119 EADRSAFRFLHVSTDEVFGSLSAADPQFSETTPYA-PNSPYSATKAGSDHLVRAYHHTYG 177 L+ S+ V+G L+ P FS P S Y+ATK ++ + Y H YG Sbjct: 117 ----KIQHLLYASSSSVYG-LNRKMP-FSTDDSVDHPVSLYAATKKANELMAHTYSHLYG 170 Query: 178 LPTLTTNCSNNYGPYQFPEKLIPLMIANALAGKALPVYGDGQNVRDWLYVGDHCSAIREV 237 LP YGP+ P+ + L GK++ VY G+ RD+ Y+ D AI + Sbjct: 171 LPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRL 230 Query: 238 L------------------ARGVPGETYNVGGWNEKKNLEVVHTLCDLLDQARPKAAGSY 279 A P YN+G + + ++ + L D L +A + Sbjct: 231 QDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGI---EAKKNM 287 Query: 280 RDQITYVTDRPGHDRRYAIDARKLERELGWKPAETFETGLAKTVAWYLDN 329 +PG + D + L +G+ P T + G+ V WY D Sbjct: 288 LPL------QPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDF 331
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 44.8 bits (106), Expect = 2e-07 Identities = 44/202 (21%), Positives = 66/202 (32%), Gaps = 63/202 (31%) Query: 11 TILVTGVNGQVGFELLRSLQGLG-RVVPCD-------------RSTL-----------DL 45 LVTG G +GF + + L G +VV D R L DL Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 46 SDLDRVRAFVRDLKPSLIVNPAAYTAVDKAESEVDAARRLNADVPRIFAE---------- 95 +D + + + A R + + P +A+ Sbjct: 62 ADREGMTDLFASGHFERVFISPH-----------RLAVRYSLENPHAYADSNLTGFLNIL 110 Query: 96 EMARTGG--ALIHYSTDYVFDGTKAGAYTETD-APNPVNAYGATKLEGER---------A 143 E R L++ S+ V+ + ++ D +PV+ Y ATK E Sbjct: 111 EGCRHNKIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYG 170 Query: 144 IAATGCAHLILRTSWVYGRRGR 165 + ATG LR VYG GR Sbjct: 171 LPATG-----LRFFTVYGPWGR 187
>PF07132#Harpin protein (HrpN) Length = 356 Score = 28.9 bits (64), Expect = 0.040 Identities = 12/30 (40%), Positives = 18/30 (60%), Gaps = 4/30 (13%) Query: 415 DDDGLTPRAREAFMA----LKSALTEENGN 440 DDDG+T + + FM +KSA+ + GN Sbjct: 293 DDDGMTKGSMDKFMKAVGMIKSAVAGDTGN 322
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 94.5 bits (235), Expect = 4e-24 Identities = 65/346 (18%), Positives = 123/346 (35%), Gaps = 57/346 (16%) Query: 7 IITGITGQDGAYLAELLLDKGYTVYG-----TYRRTSSVNFWRIEELGIAKHPNLHLVEY 61 ++TG G G ++++ LL+ G+ V G Y S + L + P + Sbjct: 4 LVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVS----LKQARLELLAQPGFQFHKI 59 Query: 62 DLTDVSASIRLLQTTGATEVYNLAAQSFVGVSFDQPVTTAEITGIGPLNLLEAIRIVNPK 121 DL D L + V+ + V S + P A+ G LN+LE R + Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ 119 Query: 122 IRFYQASTSEMFGKVQAIPQIESTPF-YPRSPYGVAKLYAHWITVNYRESYDIFGCSGIL 180 AS+S ++G + +P +P S Y K + Y Y + Sbjct: 120 -HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRF 178 Query: 181 FNHESPLRGR-EFVTRKITDSVAKIKLGQLDVLELGNMDAKRDWGFAKEYVEGMWRMLQA 239 F P GR + K T ++ + K +DV G M KRD+ + + E + R+ Sbjct: 179 FTVYGP-WGRPDMALFKFTKAMLEGK--SIDVYNYGKM--KRDFTYIDDIAEAIIRLQDV 233 Query: 240 DEPDT-------------------FVLATNRTETVRDFVRMAFKATGVDLEFKGSDANEI 280 + + + + D+++ A G+ +A + Sbjct: 234 IPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGI-------EAKKN 286 Query: 281 AVDVATGKTVVRVNPKFHRPAEVDLLIGNPEKAKQKLGWEPKTTLE 326 + + +P +V + + + +G+ P+TT++ Sbjct: 287 MLPL--------------QPGDVLETSADTKALYEVIGFTPETTVK 318
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 120 bits (302), Expect = 8e-34 Identities = 70/313 (22%), Positives = 116/313 (37%), Gaps = 42/313 (13%) Query: 11 RALVTGLGGFTGDYLAQSLRAAGYRVFG---------------TAHDAEATGVDTYRVDL 55 + LVTG GF G ++++ L AG++V G G +++DL Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 56 CDRAELAKVVADVQPDVVAHLAAIAFV--AHGDADAIYRTNVVGTRNLLEALATYGKRPN 113 DR + + A + V V + + A +N+ G N+LE Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNK--IQ 119 Query: 114 AVLLASSANIYG-NAAVEIIDESVEPNPANDYAVSKLAMEYMARLWHD--KLPIIVARPF 170 +L ASS+++YG N + + +P + YA +K A E MA + LP R F Sbjct: 120 HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFF 179 Query: 171 NYTGVGQSSQFLLPKIVGHFQRGERVIELGNIDVERDFSDVRRVVDAYRRLLQLAPAGG- 229 G L K G+ + ++RDF+ + + +A RL + P Sbjct: 180 TVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHADT 239 Query: 230 -----------------VFNVCSGRAVSLKSVIATMEQIAGYSIEVRVNPAFVRANEVRR 272 V+N+ + V L I +E G IE + N ++ +V Sbjct: 240 QWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALG--IEAKKNMLPLQPGDVLE 297 Query: 273 LQGDGSRLQAAVG 285 D L +G Sbjct: 298 TSADTKALYEVIG 310
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 110 bits (276), Expect = 5e-30 Identities = 81/348 (23%), Positives = 131/348 (37%), Gaps = 50/348 (14%) Query: 1 MTHLVITGANGFVGRALCRRALQDGHTVTALVRRPGGCIDGV-----------REWVHGT 49 M +LV TGA GF+G + +R L+ GH V ID + R + Sbjct: 1 MKYLV-TGAAGFIGFHVSKRLLEAGHQVVG--------IDNLNDYYDVSLKQARLELLAQ 51 Query: 50 ADF-----DHLDEAWPADLAA----DCVIHLAARVHVMRDESPDPDAAFDATNVVGTLRL 100 F D D DL A + V R+ V R +P A D +N+ G L + Sbjct: 52 PGFQFHKIDLADREGMTDLFASGHFERVFISPHRLAV-RYSLENPHAYAD-SNLTGFLNI 109 Query: 101 AQAARNHGVRRIVFASSIKAVGEGDDGAPLSEAVEPD-PQDAYGRSKLHAERQLAQFGAS 159 + R++ ++ +++ASS +V + P S D P Y +K E + Sbjct: 110 LEGCRHNKIQHLLYASS-SSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHL 168 Query: 160 AGLDVVVVRPPLVYGPAVRAN--FLRMMDAVARGIPLP-FGAVSARRSIVYVENLADALL 216 GL +R VYGP R + + A+ G + + +R Y++++A+A++ Sbjct: 169 YGLPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAII 228 Query: 217 RCAIDPRAAGECFHVADDDAPSVTGLLRLVGDALGKPARLVAVPPVLLRVLGKLTGRSAA 276 R A + V + R+ P L+ ++ L G A Sbjct: 229 RLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMD----YIQALEDALGIEAK 284 Query: 277 IERLTGSLQL--------DTGRIGRVLGWHPPYTTRQGLAATAAWYRS 316 L LQ DT + V+G+ P T + G+ WYR Sbjct: 285 KNML--PLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRD 330
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 122 bits (308), Expect = 4e-34 Identities = 90/388 (23%), Positives = 141/388 (36%), Gaps = 65/388 (16%) Query: 1 MKKTLIVAALAGVAASAAHAQSSVTLYGLIDAGITYTNNQHGHSAW-----QETSGSING 55 MKK+LI LA + +A + VTLYG I AG+ + + + A T G Sbjct: 1 MKKSLIALTLAALPVAAM---ADVTLYGTIKAGVETSRSVAHNGAQAASVETGTGIVDLG 57 Query: 56 SRWGLRGTEDLGGGLKAIFTLENGFGINNGSLKQNGREFGRQAFVGLAHESYGSLTLGRQ 115 S+ G +G EDLG GLKAI+ +E I + RQ+F+GL +G L +GR Sbjct: 58 SKIGFKGQEDLGNGLKAIWQVEQKASIAGT----DSGWGNRQSFIGLKGG-FGKLRVGRL 112 Query: 116 YDSVVDYLG--PLSLTGTQYGGTQFAHPFDNDNLNNSFRINNSVKYQSANYGGLKFGGLY 173 + D P G + A P + I SV+Y S + GL Y Sbjct: 113 NSVLKDTGDINPWDSKSDYLGVNKIAEP-------EARLI--SVRYDSPEFAGLSGSVQY 163 Query: 174 GFSNSTGFANNRAYSVGASYSYMGFNVAAAYMQLNNNINALALAASDPGAVAGDWTFAAS 233 +++ G N+ +Y G +Y GF V ++ Sbjct: 164 ALNDNAGRHNSESYHAGFNYKNGGFFVQYGGAYKRHH--------------QVQENVNIE 209 Query: 234 RQRTWGAGLNYTFGPATAGFVFTQTRLTNSAGISAGQSGVS-TGIPLAGGTRFNNYEVNG 292 + + Y A + + ++ + S S T + RF N Sbjct: 210 KYQIHRLVSGYD---NDALYASVAVQQQDAKLVEENYSHNSQTEVAATLAYRFGNV---- 262 Query: 293 RYALTPAFSLAGSYTYTDSRLDGQTPSWHQFNLQADYALSKRTDLYLQSEYQRVNANGLA 352 ++ A GS+ T+ + Q + A+Y SKRT + + + + Sbjct: 263 TPRVSYAHGFKGSFDATNY-----NNDYDQVVVGAEYDFSKRTSALVSAGWLQEG----- 312 Query: 353 IGANINGLGAASSTNKQIAVTAGMRHRF 380 G ST A G+RH+F Sbjct: 313 -----KGESKFVST----AGGVGLRHKF 331
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.6 bits (69), Expect = 0.002 Identities = 9/74 (12%), Positives = 26/74 (35%), Gaps = 2/74 (2%) Query: 32 FLSKRRLLISTWIDVHDTLAEIAQTRDNIASARQRILELPDNAPARAELLTRIEDQSARV 91 L + + ++ +++ Q I SA++ + + E+L ++ + + Sbjct: 254 VLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQL--FKNEILDKLRQTTDNI 311 Query: 92 AEQYAALQFAREQL 105 L E+ Sbjct: 312 GLLTLELAKNEERQ 325
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 45.0 bits (106), Expect = 3e-07 Identities = 24/126 (19%), Positives = 37/126 (29%) Query: 107 VAPEPGEPPATIEPPSPRPPAIVEPAPPEPAPEPPAIVEPAPPEPAPEPPAIVEPAPPDP 166 V P EPP ++PP P P P A V P+P P+P + Sbjct: 50 VTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQ 109 Query: 167 PPALDTSLAIRNLATGGALCLGMSTGNGTYVGFQSCNGSDAQRWRMVRAASPYFNVKNVL 226 P + R + T + S A R + P + + Sbjct: 110 PKRDVKPVESRPASPFENTAPARLTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQA 169 Query: 227 AEAQGR 232 +G+ Sbjct: 170 LRIEGQ 175 Score = 43.8 bits (103), Expect = 7e-07 Identities = 21/93 (22%), Positives = 27/93 (29%), Gaps = 5/93 (5%) Query: 96 APPDPSYPRPPVAPEPGEPPATIEPPSPRPPAIVEPAPPEPAPEPPAIVEPAPPEPAPEP 155 P + PP EP P P+ +V P+P P+P E Sbjct: 55 LEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIE-KPKPKPKPKPKPVKKVQEQPKRD 113 Query: 156 PAIVEPAPPDP----PPALDTSLAIRNLATGGA 184 VE P P PA TS + Sbjct: 114 VKPVESRPASPFENTAPARLTSSTATAATSKPV 146 Score = 40.4 bits (94), Expect = 1e-05 Identities = 18/53 (33%), Positives = 21/53 (39%) Query: 118 IEPPSPRPPAIVEPAPPEPAPEPPAIVEPAPPEPAPEPPAIVEPAPPDPPPAL 170 IE P+P P V P P A+ P P PEP P PP P + Sbjct: 36 IELPAPAQPISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVV 88 Score = 31.9 bits (72), Expect = 0.006 Identities = 17/97 (17%), Positives = 20/97 (20%), Gaps = 6/97 (6%) Query: 79 PAPEIVADGVAVSDEPG-APPDPSYPRPPV-APEPGEPPATIEPPSPRPPAIVEPAPPEP 136 P+ V EP P P P P P +P Sbjct: 56 EPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVK 115 Query: 137 APEPPAIVEPAPPEPAPEPPAIVEPAPPDPPPALDTS 173 E PA P P + TS Sbjct: 116 PVESR----PASPFENTAPARLTSSTATAATSKPVTS 148
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 48.3 bits (115), Expect = 3e-08 Identities = 59/364 (16%), Positives = 121/364 (33%), Gaps = 52/364 (14%) Query: 48 SAFPDSASWIGAVPTATQLGYAAGMFLLAPLGDRFDRRGLILLQIAGLSIALIVAAAAPS 107 + P S +W V TA L ++ G + L D+ + L+L I ++ S Sbjct: 45 NKPPASTNW---VNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHS 101 Query: 108 LA---VLAAASLAIGVLATIAQQAVPFAAEIAPPAERGHAVGTVMSGLLLGILLARTAAG 164 ++A G A A V A I P RG A G + S + +G + G Sbjct: 102 FFSLLIMARFIQGAGAAAFPALVMVVVARYI-PKENRGKAFGLIGSIVAMGEGVGPAIGG 160 Query: 165 FVAEYFGWRAVFGASVAALAALAAVIVLRLPRSSPTSTL--------------------S 204 +A Y W + + + + ++ L S Sbjct: 161 MIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTS 220 Query: 205 YGKLLGSMWHLAVEL--RGLREAS------------------LTGAALFAAFSAFWPVLT 244 Y + L+ + + +R+ + L G +F + F ++ Sbjct: 221 YSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVP 280 Query: 245 LLLAGAPFHLGPQAAG--LFGIVGAAGALAAPYAGRFADKRGPRAIISLAIALLAASFVI 302 ++ L G + + + G D+RGP ++++ + L+ SF+ Sbjct: 281 YMM-KDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLT 339 Query: 303 FA-LSGTSLVGLVIGVIVLDVGVQAAQIS-NQSRIYALKPDARSRVNTVYMVCYFIGGAL 360 + L T+ + I ++ + G+ + + +LK ++ F+ Sbjct: 340 ASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGT 399 Query: 361 GSSV 364 G ++ Sbjct: 400 GIAI 403
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.9 bits (64), Expect = 0.034 Identities = 14/37 (37%), Positives = 20/37 (54%), Gaps = 3/37 (8%) Query: 21 RVLEPLDLSIGAGETLVLLGPSGCGKTTTLRLIAGLD 57 RV+EP ++VL G G GK+T + + GLD Sbjct: 587 RVMEP---GCKFDYSVVLEGTGGIGKSTLINTLVGLD 620
>NEISSPPORIN#Neisseria sp. porin signature. Length = 348 Score = 82.0 bits (202), Expect = 9e-20 Identities = 97/338 (28%), Positives = 145/338 (42%), Gaps = 45/338 (13%) Query: 6 AALAQDGVTLYGVID---EFAQYVNTGNGYTAAIGSGGQ---WGSRFGMKGGEDLGGGQK 59 AA+A VTLYG I + + V +G + + +G + +GS+ G KG EDLG G K Sbjct: 16 AAMAD--VTLYGAIKAGVQTYRSVEHTDGKVSKVETGSEIADFGSKIGFKGQEDLGNGLK 73 Query: 60 VEFALENGFNPNDGSLASSGSMF-NRQAWVGIAGQWGKVRAGRQNSPLFNDQGGQDAFGG 118 + LE S+A + + + N+Q++VG+ G +G +RAG NSPL N +A+ Sbjct: 74 AVWQLEQ-----GASVAGTNTGWGNKQSFVGLKGGFGTIRAGSLNSPLKNTGANVNAWES 128 Query: 119 VTQASGMDNLTVFAFRTSNTLS--YQSPEIGGFQGGLYFGFGDAGGVRSAGSSRQFDLTY 176 + ++ A R LS Y SPE GF G + + D G S G S L Y Sbjct: 129 GKFTGNVLEISGMAQREHRYLSVRYDSPEFAGFSGSVQYAPKDNSG--SNGESYHVGLNY 186 Query: 177 EHGPFAAFVAGQWLK---STTTTTTDRTIMAGASYAIGKATVY---GGFSA----VKWAD 226 ++ F A AG + + T D + S + K V+ GG+ V A Sbjct: 187 QNSGFFAQYAGLFQRYGEGTKKIEYDDQTYSIPSLFVEKLQVHRLVGGYDNNALYVSVAA 246 Query: 227 LGIDSRVYGLSLKYQLNPANYVALGYAY-----------------LHDQTSQGNNADQLG 269 D+++YG N VA AY D + N DQ+ Sbjct: 247 QQQDAKLYGAMSGNSHNSQTEVAATAAYRFGNVTPRVSYAHGFKGTVDSANHDNTYDQVV 306 Query: 270 LMYEYDLSKRTSFYGALSYLRNRNQAGYTLAGAANPGL 307 + EYD SKRTS + +L+ A ++ A+ L Sbjct: 307 VGAEYDFSKRTSALVSAGWLQGGKGADKIVSTASAVVL 344
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 41.7 bits (98), Expect = 3e-06 Identities = 77/398 (19%), Positives = 134/398 (33%), Gaps = 39/398 (9%) Query: 10 RPDGSAALPLLALAAGAFGIGTTEFSPMGLLPVIADGVHVSIPQA---GMLISAYAIGVM 66 +P+ + L +A A GIG M +LP + + S G+L++ YA+ Sbjct: 2 KPNRPLIVILSTVALDAVGIGLI----MPVLPGLLRDLVHSNDVTAHYGILLALYALMQF 57 Query: 67 VGAPLMTLLLARWSRRSALIALMSIFTIGNLLSAIAPDYTTLLLARLVTSLNHGAFFGLG 126 AP++ L R+ RR L+ ++ + + A AP L + R+V + G Sbjct: 58 ACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAG 117 Query: 127 SVVAAGLVPRERQASAVATMFMGLTIANVGGVPAATWLGQMIGWRMSFAATAALGLIAIA 186 + + A + + +A M V G +G F A AAL + Sbjct: 118 AYI-ADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFAAAALNGLNFL 175 Query: 187 GLFAALP-------RGEAGKMPNLRAELSVLTRPVVLGALATTVLGA-------GAMFTL 232 LP R + N A V+ AL A++ + Sbjct: 176 TGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVI 235 Query: 233 YTYVAPTLEHVTGATPGFVTAMLVLIGVGFSIGNI-AGGRLADRSLDATLIGFLVLLIVT 291 + E + L G+ S+ G +A R + + ++ +I Sbjct: 236 FG------EDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRAL--MLGMIAD 287 Query: 292 MAGFPLLARTHVGAAATLLVWGVATFAVVPPLQMRVM--RAAHEAPGLASAVNIGAFNLG 349 G+ LLA G A ++ +A+ + P ++ + E G +L Sbjct: 288 GTGYILLAFATRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLT 347 Query: 350 NALGAAAGGAAISAGFGYAAVPLVGGLIAAAGLALVAL 387 + +G A +A G AG AL L Sbjct: 348 SIVGPLLFTAIYAASITTW-----NGWAWIAGAALYLL 380
>PERTACTIN#Pertactin signature. Length = 922 Score = 36.2 bits (83), Expect = 2e-04 Identities = 25/66 (37%), Positives = 28/66 (42%) Query: 192 KEPVAPLPEPAPTPQGEPMKMTTPVVPTPPAAPVPLSVPSVAPTPGTPVVPAVPAPASAV 251 K P AP P P P PQ P P P PP P P AP P P + A A+A Sbjct: 566 KAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPPAGRELSAAANAA 625 Query: 252 VAPGAM 257 V G + Sbjct: 626 VNTGGV 631
>ARGDEIMINASE#Bacterial arginine deiminase signature. Length = 409 Score = 30.2 bits (68), Expect = 0.021 Identities = 10/47 (21%), Positives = 19/47 (40%), Gaps = 6/47 (12%) Query: 182 QVDRIVDKVPRVDIPGDRVHFV--VEAGRPFYVEPL----FTRDPAA 222 + +++ V ++ V F ++P+ FTRDP A Sbjct: 121 MISKMISGVVTEELKNYTSSLDDLVNGANLFIIDPMPNVLFTRDPFA 167
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 85.7 bits (212), Expect = 2e-21 Identities = 36/136 (26%), Positives = 64/136 (47%), Gaps = 5/136 (3%) Query: 5 ILVVEDEPAISELISVNLQHAGHCPIRAYNAEQAQNLISDVLPDLVLLDWMLPGKSGIAF 64 ILV +D+ AI +++ L AG+ NA I+ DLV+ D ++P ++ Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 65 ARDLRNNERTKHIPIIMLTARGDEQDKVLGLEIGADDYVTKPFSPKELMARIKAVL---R 121 ++ + +P+++++A+ + E GA DY+ KPF EL+ I L + Sbjct: 66 LPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 122 RRAPQLTEDVVSINGL 137 RR +L +D L Sbjct: 124 RRPSKLEDDSQDGMPL 139
>PF06580#Sensor histidine kinase Length = 349 Score = 39.8 bits (93), Expect = 1e-05 Identities = 20/106 (18%), Positives = 35/106 (33%), Gaps = 26/106 (24%) Query: 328 LVTNAIRY----TPDGGKIFVSWRREGAQGVFSVTDSGFGIPAADLPRLTERFYRVDRSR 383 LV N I++ P GGKI + ++ V ++G Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLAL------------------ 304 Query: 384 SRDTGGTGLGLAIVKHVLQR---HDSHLYVQSEEGRGSTFTARFPA 426 TG GL V+ LQ ++ + + ++G+ P Sbjct: 305 KNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKV-NAMVLIPG 349
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 89.7 bits (222), Expect = 3e-23 Identities = 68/238 (28%), Positives = 109/238 (45%), Gaps = 13/238 (5%) Query: 2 AYDLQGKVVLITGAAGGIGAATARALHACGARLVLTDVTQASVDRLAAEFDSE--RTLAL 59 A ++GK+ ITGAA GIG A AR L + GA + D ++++ + +E A Sbjct: 3 AKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAF 62 Query: 60 ALDVTDAAATKAVVQHAVDRFGRLDIAFANAGISWLDVPATVYSCDEQEFERIVEVDLLG 119 DV D+AA + G +DI AG+ P ++S ++E+E V+ G Sbjct: 63 PADVRDSAAIDEITARIEREMGPIDILVNVAGVLR---PGLIHSLSDEEWEATFSVNSTG 119 Query: 120 VWRTIKAALPEIVRNRGQVLVT-ASVYAFVNGMVNAPYAASKAAVEMLARSLRAELGGTG 178 V+ ++ ++ R +VT S A V A YA+SKAA M + L EL Sbjct: 120 VFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYN 179 Query: 179 STASVLYPGWVATAIAKISFGGNALATKLIEKGFPA------PLRRPIQPDDVAKAVI 230 +++ PG T + + A ++I KG PL++ +P D+A AV+ Sbjct: 180 IRCNIVSPGSTETDMQWSLWADENGAEQVI-KGSLETFKTGIPLKKLAKPSDIADAVL 236
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 66.2 bits (161), Expect = 8e-15 Identities = 46/182 (25%), Positives = 82/182 (45%), Gaps = 6/182 (3%) Query: 1 MSTYKLANKVVAITGSTGGLGSALAEALHARGARLALFDLEADRLTAQTRSF---GRPSD 57 M+ + K+ ITG+ G+G A+A L ++GA +A D ++L S R ++ Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE 60 Query: 58 VLGWTADVRDFESIEAAMANAADHFGQIDVVIANAGIDTMAPMATIDPAAFDRVIDINLN 117 ADVRD +I+ A G ID+++ AG+ + ++ ++ +N Sbjct: 61 AF--PADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNST 118 Query: 118 GVWRTFRAGLP-FVQQQRGYMLAISSMAAFVHSPLQASYTASKAGVWAMCDSIRLELRHL 176 GV+ R+ + ++ G ++ + S A V A+Y +SKA + LEL Sbjct: 119 GVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEY 178 Query: 177 GI 178 I Sbjct: 179 NI 180
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 70.4 bits (172), Expect = 4e-17 Identities = 28/175 (16%), Positives = 66/175 (37%), Gaps = 8/175 (4%) Query: 1 MESRTQRRVAATRLAILQAAETLLTEGGLDAVTPEAVATRADVAVQTLYNRVGGRSALLI 60 M +T++ TR IL A L ++ G+ + + +A A V +Y +S L Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 AVAERALEENREYMDAAYASD-GDVETKLRCVAAAYARFAKERPHQFRILVEPPNEPEAL 119 + E + E A GD + LR + + ++ ++ E + Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 120 ARIAALIR-------QQNAKLAALISRGIDEGWVHAEVEPEHASTALWAMMNGVI 167 +A + + + ++ + I+ + A++ A+ + ++G++ Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLM 175
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 106 bits (265), Expect = 7e-30 Identities = 69/242 (28%), Positives = 111/242 (45%), Gaps = 12/242 (4%) Query: 1 MNQIELSGRVVVITGGARGIGYAAAQRALRSGAAVSLWDVDGERLARSQRELSELG-TVS 59 MN + G++ ITG A+GIG A A+ GA ++ D + E+L + L Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE 60 Query: 60 TVVVELTDEASVDAAATATFERHGAIDVLINSAGITGGNGLTWELPPDVWRRVIDVNLIG 119 ++ D A++D G ID+L+N AG+ GL L + W VN G Sbjct: 61 AFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLR-PGLIHSLSDEEWEATFSVNSTG 119 Query: 120 SYLTCRAVVPRMLEKGYGRIVNIASVAGKEGNPTASHYSASKAGLIGLTKSLGKELATRG 179 + R+V M+++ G IV + S + + Y++SKA + TK LG ELA Sbjct: 120 VFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYN 179 Query: 180 ILVNAVTPAAAKTEIFDSM------SQQHIDYMLSK----IPMNRFLMPEEAASLILWLA 229 I N V+P + +T++ S+ ++Q I L IP+ + P + A +L+L Sbjct: 180 IRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLV 239 Query: 230 SE 231 S Sbjct: 240 SG 241
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 117 bits (295), Expect = 5e-34 Identities = 74/260 (28%), Positives = 118/260 (45%), Gaps = 17/260 (6%) Query: 3 LEDKVVIVTGGSRGIGRAIAVASAREGADVVVNYWGDNDASYGRRSAIAEVVAEVERAGR 62 +E K+ +TG ++GIG A+A A +GA + A + +VV+ ++ R Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIA--------AVDYNPEKLEKVVSSLKAEAR 57 Query: 63 RAIAIEGNVALPQTGIDLVRHAVDAFGKVDVLASNAGICPFHAFLDMPPSVLERTIGVNL 122 A A +V ++ G +D+L + AG+ + E T VN Sbjct: 58 HAEAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNS 117 Query: 123 NGAFYVTQAVARQMKEQGTGGAIVATSSISALVGGGMQTHYTPTKAGVHSLMQSCAIALG 182 G F +++V++ M ++ G+IV S A V Y +KA + + L Sbjct: 118 TGVFNASRSVSKYMMDR-RSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELA 176 Query: 183 PYGIRCNSVMPGTIATDLNAADLEDEDKRRY--------FEKRIPLGRLGQPEDVADCVV 234 Y IRCN V PG+ TD+ + DE+ F+ IPL +L +P D+AD V+ Sbjct: 177 EYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVL 236 Query: 235 FLASDRARYVTGAALLVDGG 254 FL S +A ++T L VDGG Sbjct: 237 FLVSGQAGHITMHNLCVDGG 256
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 84.9 bits (210), Expect = 4e-20 Identities = 35/157 (22%), Positives = 62/157 (39%), Gaps = 2/157 (1%) Query: 7 DAPVVLVVDDTAANLALVVDTLEAEGLSVAVARDGHEALRRAELVKPDLILLDVMMPGLD 66 +LV DD AA ++ L G V + + R DL++ DV+MP + Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 67 GFQTCRALKDNPVTRDIPVIFMTSLTQTEDKITGFRVGAMDFVTKPLQMEEVAVRVQMHL 126 F +K D+PV+ M++ I GA D++ KP + E+ + L Sbjct: 62 AFDLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119 Query: 127 KLHALQRLQQEQNARLEEEIKTRVQAQDALIEVLDGV 163 + + E +++ + R A + VL + Sbjct: 120 AEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARL 156
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 28.0 bits (62), Expect = 0.016 Identities = 15/46 (32%), Positives = 24/46 (52%), Gaps = 2/46 (4%) Query: 15 GALDAGAWAIAAALAAAGAGWWIASGWAPSTVARVLLAVVSSGSGI 60 GA+DA I+ LA+ +G A+ S V + A+V + +GI Sbjct: 362 GAIDASLTTISTVLASVSSGISAAA--TTSLVGAPVSALVGAVTGI 405
>TYPE3OMOPROT#Type III secretion system outer membrane O protein family signature. Length = 303 Score = 31.9 bits (72), Expect = 0.006 Identities = 22/56 (39%), Positives = 27/56 (48%), Gaps = 8/56 (14%) Query: 491 DALRHCRPRRAGDVVTADAAHLYVFLFACEPVDAEDALARIFDVPVDTLSDRVVCL 546 D L H P AG V+A A HL V A A R F++PV LS R +C+ Sbjct: 58 DWLEHVSPALAGAAVSAGAEHLVVPWLA--------ATERPFELPVPHLSCRRLCV 105
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 105 bits (262), Expect = 2e-29 Identities = 77/254 (30%), Positives = 121/254 (47%), Gaps = 14/254 (5%) Query: 4 LTGKVAIVTGGSKGIGAAIAKALAAEGASVV-VNYASSKAGADTVVSAIVEAGGRAVAVG 62 + GK+A +TG ++GIG A+A+ LA++GA + V+Y K + VVS++ A A Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKL--EKVVSSLKAEARHAEAFP 63 Query: 63 GDVSKAADAQRIVDAAIENYGRLDVLVNNSGVYEFSPIEAITEEHYRRQFDTNVFGVLLT 122 DV +A I G +D+LVN +GV I ++++E + F N GV Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 123 TQAAVKHL--GEGASIINISSVVTSITPPASAVYSGTKGAVDAITGVLALELGPRKIRVN 180 +++ K++ SI+ + S + + A Y+ +K A T L LEL IR N Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 181 AINPGMIVTEGTHS--------AGIIGSDLETQVRSQTPLGRLGEPDDIASVAVFLASDD 232 ++PG T+ S +I LE ++ PL +L +P DIA +FL S Sbjct: 184 IVSPGSTETDMQWSLWADENGAEQVIKGSLE-TFKTGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 233 ARWLTGERLVASGG 246 A +T L GG Sbjct: 243 AGHITMHNLCVDGG 256
>SOPEPROTEIN#Salmonella type III secretion SopE effector protein signature. Length = 239 Score = 31.2 bits (70), Expect = 0.004 Identities = 19/52 (36%), Positives = 26/52 (50%), Gaps = 8/52 (15%) Query: 148 IPPFIATLGTMVAARGFAKWFTNGMPVSMLTDQFAAIGAGANPVIIFLVVAA 199 I PF+ +G AA+ G+P + D F GAGANP I L+ +A Sbjct: 136 IAPFLQEIGE--AAK------NAGLPGTTKNDVFTPSGAGANPFITPLISSA 179
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 85.5 bits (211), Expect = 3e-22 Identities = 61/254 (24%), Positives = 110/254 (43%), Gaps = 22/254 (8%) Query: 5 LHGKKVLVVGGSSGIGAAAAKAFAQRGAVVTIASRDPARAGADVAPDG----HVRTEALD 60 + GK + G + GIG A A+ A +GA + +P + V+ H D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 61 ITDTAAVDAFCAR----VGQFDHVVISAAKTATGPLRALPLADAQAAMDSKFWGAY---- 112 + D+AA+D AR +G D +V A G + +L + +A G + Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 113 RIARSIDIAPGGSLTFVSGYLSVRPSTSSVLQGAINAALEALARGLALELAP--VRVNTV 170 +++ + GS+ V + P TS + AA + L LELA +R N V Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 171 SPGLIATPLWDKL--APDVRDAMYAGAAQR----LPARRVGQPEDVANAIVYLAT--TPY 222 SPG T + L + + + G+ + +P +++ +P D+A+A+++L + + Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGH 245 Query: 223 ATGSTVLIDGGGAI 236 T + +DGG + Sbjct: 246 ITMHNLCVDGGATL 259
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 118 bits (298), Expect = 3e-38 Identities = 35/89 (39%), Positives = 53/89 (59%) Query: 39 TKAELAELLFDSVGLNKREAKDMVEAFFEVIRDALENGESVKLSGFGNFQLRDKPQRPGR 98 K +L + ++ L K+++ V+A F + L GE V+L GFGNF++R++ R GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 99 NPKTGEAIPIAARRVVTFHASQKLKALVE 127 NP+TGE I I A +V F A + LK V+ Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAVK 91
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 31.2 bits (70), Expect = 0.016 Identities = 30/177 (16%), Positives = 55/177 (31%), Gaps = 18/177 (10%) Query: 13 AAQAARADDAPEQDAPAAGGDERPRRGLRRGPRSLIARRRAA--AKSKGAEGESQDGEGA 70 + Q ++ + EQDA R + ++ A + A+S E+Q E Sbjct: 1044 SKQESKTVEKNEQDATETTAQNR--EVAKEAKSNVKANTQTNEVAQSGSETKETQTTETK 1101 Query: 71 DAPPAEAAEAQPARAPRKEGAARGGRKPAAKREGAPKGAQGGQGGQGRRGSPAKAEGGAA 130 + E E + + + + + K+E Q + + E Sbjct: 1102 ETATVEKEEKAKVETEKTQEVPKVTSQVSPKQE---------QSETVQPQAEPARENDPT 1152 Query: 131 KAEGDAASQDDLFAYVTSPAFDADNSAGGSGVRAPMLRRGRTQPTNKRVLSPDDDAP 187 + SQ + A PA S V P+ N V +P++ P Sbjct: 1153 VNIKEPQSQTNTTADTEQPA-----KETSSNVEQPVTESTTVNTGNSVVENPENTTP 1204
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 27.6 bits (61), Expect = 0.028 Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 10/55 (18%) Query: 112 EGRALAERLPPVFRSVLDELLGG----------FTPEEVGFLKSMLRRILSNYCE 156 +G A+ E P + S++D L GG T E ++ ++ RIL+N E Sbjct: 112 KGNAVLEVDPSITFSIIDRLFGGTGQAAKVQRDLTDIENSVMEGVIVRILANVRE 166
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 169 bits (429), Expect = 3e-47 Identities = 99/435 (22%), Positives = 170/435 (39%), Gaps = 62/435 (14%) Query: 5 LRNIAIIAHVDHGKTTLVDQLLRQSGTFRENQQIAE--RVMDSNDIEKERGITILAKNCA 62 + NI ++AHVD GKTTL + LL SG E + + D+ +E++RGITI + Sbjct: 3 IINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITS 62 Query: 63 VEYEGTHINIVDTPGHADFGGEVERVLSMVDSVLLLVDAVEGPMPQTRFVTKKALALGLK 122 ++E T +NI+DTPGH DF EV R LS++D +LL+ A +G QTR + +G+ Sbjct: 63 FQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIP 122 Query: 123 PIVIVNKIDRPGARIDWV-------------INQTFDLFDKLGATE----EQLDFPIV-- 163 I +NKID+ G + V I Q +L+ + T EQ D I Sbjct: 123 TIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGN 182 Query: 164 -----------------YASGLNGY---ASLDP-----AAREGDMRPLFEAVLQHVPVRP 198 + SL P A + L E + Sbjct: 183 DDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSST 242 Query: 199 ADPDAPLQLQITSLDYSTYVGRIGVGRITRGRIKPGQPVAMRFGPEGDVLNRKINQVLSF 258 + L ++ ++YS R+ R+ G + V R + + KI ++ + Sbjct: 243 HRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSV--RISEKEKI---KITEMYTS 297 Query: 259 TGLERVQVDSAEAGDIVLINGIEDVGIGATICAVDTPEALPMITVDEPTLTMNFLVNSSP 318 E ++D A +G+IV++ E + + + + I P L + Sbjct: 298 INGELCKIDKAYSGEIVILQN-EFLKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQ 356 Query: 319 LAGREGKFVTSRQIRDRLMKELNHNVALRVKDTGDETVFEVSGRGELHLTILVENMRRE- 377 + D L++ V E + +S G++ + + ++ + Sbjct: 357 QREMLLDALLEISDSDPLLR-------YYVDSATHEII--LSFLGKVQMEVTCALLQEKY 407 Query: 378 GYELAVSRPRVVMQE 392 E+ + P V+ E Sbjct: 408 HVEIEIKEPTVIYME 422 Score = 34.4 bits (79), Expect = 0.001 Identities = 16/100 (16%), Positives = 32/100 (32%), Gaps = 1/100 (1%) Query: 387 RVVMQEIDGVRHEPYELLTVDVEDEHQGGVMEELGRRKGEMLDMASDGRGRTRLEYKISA 446 V+++ EPY + E+ + + ++D L +I A Sbjct: 525 EQVLKKAGTELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVD-TQLKNNEVILSGEIPA 583 Query: 447 RGLIGFQSEFLTLTRGTGLMSHIFDSYAPVKDGSVFERRN 486 R + ++S+ T G + Y V + R Sbjct: 584 RCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRR 623
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.7 bits (72), Expect = 0.005 Identities = 9/92 (9%), Positives = 29/92 (31%), Gaps = 5/92 (5%) Query: 48 EVPAPAAGVLAQVLQNDGDTVVADQIIATID---TEAKAGAAEAAAGAAEVKPAAAPAAA 104 E+ ++ +++ +G++V ++ + EA +++ A + Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARL--EQTRYQI 155 Query: 105 APAAQPAAAVASSSAAASPAASKLLAEKGLSA 136 + + P + E+ L Sbjct: 156 LSRSIELNKLPELKLPDEPYFQNVSEEEVLRL 187
>cloacin#Cloacin signature. Length = 551 Score = 35.5 bits (81), Expect = 5e-04 Identities = 29/83 (34%), Positives = 35/83 (42%), Gaps = 5/83 (6%) Query: 30 GGSGSISKGISGGSGSGGSDSISTSGGGTSSGTSGSTSGGTSGSTSGSTSGSTSGSTSGS 89 G+ S S I+GG G ++ G G SS + GG SGS GS G+ G Sbjct: 11 TGAHSTSGNINGGPTGLGVGGGASDGSGWSS--ENNPWGGGSGSGIHWGGGSGHGNGGG- 67 Query: 90 TSGTTSGTSSGTSGTSGVSANPV 112 SG SGT G A PV Sbjct: 68 --NGNSGGGSGTGGNLSAVAAPV 88
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 44.8 bits (106), Expect = 3e-08 Identities = 27/120 (22%), Positives = 50/120 (41%), Gaps = 10/120 (8%) Query: 10 FLGWAAFVAAGDIRFRRIRNSLVVAGLFGALVAAAIGRNPFGISLTQSLVGAAVGLVCFF 69 + D+ + + L + L+G L+ + F +SL +++GA G + + Sbjct: 140 LTWVLVALTFIDLDKMLLPDQLTLPLLWGGLLFNLL--GGF-VSLGDAVIGAMAGYLVLW 196 Query: 70 PLFAL-------RVMGAADVKVFAVLGAWCGAPMLLLLWIVGSLAAGVHALCVMLLSRTS 122 L+ MG D K+ A LGAW G L ++ ++ SL + ++LL Sbjct: 197 SLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALPIVLLLSSLVGAFMGIGLILLRNHH 256
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 140 bits (353), Expect = 6e-38 Identities = 61/249 (24%), Positives = 115/249 (46%), Gaps = 8/249 (3%) Query: 177 VQVDVRVVEFSRSVLKQVGFNF-FKQSNGFSFGSFSPGGVQSYNGGSGPGTAGYIPALGA 235 V V+ + E + +G + K + F + + G + G + + A Sbjct: 347 VLVEAIIAEVQDADGLNLGIQWANKNAGMTQFTNSGLPISTAIAGANQYNKDGTVSSSLA 406 Query: 236 PVASAFNLVVNAAGRGIF-ADLSLLEANNMARVLAEPTLVALSGQSASFLAGGEIPVPSP 294 S+FN + +G + L+ L ++ +LA P++V L A+F G E+PV + Sbjct: 407 SALSSFNGIAAGFYQGNWAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVPVLTG 466 Query: 295 QGLGSTA-----IQWKQYGVGLSLTPTVLGPNRIALKVAPESSQLDFVNSVTISGVAVPG 349 S ++ K G+ L + P + + + L++ E S + S T S + Sbjct: 467 SQTTSGDNIFNTVERKTVGIKLKVKPQINEGDSVLLEIEQEVSSVADAASSTSSDLGAT- 525 Query: 350 ITTRRADTTVELGDGESFVIGGLIDRQTMSNVSKVPLLGDLPIIGTFFKNLNYQQNDKEL 409 TR + V +G GE+ V+GGL+D+ KVPLLGD+P+IG F++ + + + + L Sbjct: 526 FNTRTVNNAVLVGSGETVVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRNL 585 Query: 410 LIIVTPHLV 418 ++ + P ++ Sbjct: 586 MLFIRPTVI 594
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 37.5 bits (87), Expect = 1e-04 Identities = 22/131 (16%), Positives = 46/131 (35%), Gaps = 12/131 (9%) Query: 24 EAHVRW-LADTLVSAG--AVEAASLEPGMLAQRITGLNPALVFIDFSERSDAASVAAAAV 80 +A +R L L AG ++ + I + LV D + A + Sbjct: 12 DAAIRTVLNQALSRAGYDVRITSNAATLW--RWIAAGDGDLVVTDVVMPDENAFDLLPRI 69 Query: 81 RAAYPALPIVALGSLAQPESTLAALRAGVRDFI-------DVSASAEEALRTTRGLLSHV 133 + A P LP++ + + + + A G D++ ++ AL + S + Sbjct: 70 KKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPSKL 129 Query: 134 SEPASRHGKVV 144 + + +V Sbjct: 130 EDDSQDGMPLV 140
>PF07132#Harpin protein (HrpN) Length = 356 Score = 28.9 bits (64), Expect = 0.039 Identities = 13/21 (61%), Positives = 13/21 (61%) Query: 431 GGMGGGGFGGGFGGGGFGRGG 451 G M GGG GGG GG G GG Sbjct: 62 GSMMGGGLGGGLGGLGSSLGG 82
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 30.0 bits (67), Expect = 0.037 Identities = 61/267 (22%), Positives = 96/267 (35%), Gaps = 30/267 (11%) Query: 44 TSDPSGCLSDAKNNVTSSANI----NDKGYAFTLISATATANPTAGNDQIAVSCGRWDSA 99 + P G D N+ S+ NDK + S T NP N + + Sbjct: 324 IAPPEGGYKDKPNDKPSNTTQNNAKNDKQESSQNNSNTQVINPP--NSA-----QKTEIQ 376 Query: 100 TAYVTPASASANAAQVTAYRQVNYFFLGLLSQLSGRQAVVSATATARAAAIDTFSVGSTL 159 V + V VN + + + R A+ T AA + G L Sbjct: 377 PTQVIDGPFAGGKNTV-----VNINRINTNADGTIRVGGFKASLTTNAAHLHIGKGGINL 431 Query: 160 ANLNTSSSAILDPLLTGL-LGATTNVNVGLANYQALAGANVTLGQLATVATQLGTAGMSS 218 +N + S +++ L + + VN ALAG++ A T+ GTA ++ Sbjct: 432 SNQASGRSLLVENLTGNITVDGPLRVN-NQVGGYALAGSSANFEFKAGTDTKNGTATFNN 490 Query: 219 PASVGKLLGLNLTVSDILSLTATAVGSNTTVGTVLTALKTSVGANVNANKISLGSLLQYS 278 S+G+ +NL V + TA G +T G T + V VN NK+ + Sbjct: 491 DISLGRF--VNLKVD---AHTANFKGIDTGNGGFNTLDFSGVTNKVNINKLI-------T 538 Query: 279 GGNAEAAANASINVLQLLLATAEIGAY 305 A N +IN L + +G Y Sbjct: 539 ASTNVAVKNFNINELVVKTNGVSVGEY 565
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 676 bits (1747), Expect = 0.0 Identities = 240/855 (28%), Positives = 360/855 (42%), Gaps = 65/855 (7%) Query: 1 MLVVVSPSHATEFNSSFLDIDGTSNVDLSQFSQPDFTLPGEYMLDVQVNDLFYGLQAIQF 60 S FN FL D + DLS+F PG Y +D+ +N+ + + + F Sbjct: 37 AAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGYMATRDVTF 96 Query: 61 IALDASGAGKPCLPPELVARFGLKPSLAKDLPRLQGGRCVDLG-AIEGATVRYLKSDGRL 119 D+ PCL +A GL + + L CV L I AT + RL Sbjct: 97 NTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLTSMIHDATAQLDVGQQRL 156 Query: 120 KITIPQAALEFTDSTYLPPSSWSDGIAGAMLDYRVIANTNRNFGSDGGQTNSIQAYGTIG 179 +TIPQA + Y+PP W GI +L+Y N+ +N GG ++ G Sbjct: 157 NLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRI--GGNSHYAYLNLQSG 214 Query: 180 ANWDAWRLRGDYQAQSNVGNTAYADRT-FRFSRLYAFRALPSIQSTVTFGDDYLSSDIFD 238 N AWRLR + N +++ + ++ + R + ++S +T GD Y DIFD Sbjct: 215 LNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTLGDGYTQGDIFD 274 Query: 239 TFALTGASIRSDDRMLPPSLRGYAPLISGVARTNATVTVSQAGRVLYVTRVSPGAFALQN 298 GA + SDD MLP S RG+AP+I G+AR A VT+ Q G +Y + V PG F + + Sbjct: 275 GINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPPGPFTIND 334 Query: 299 IN-TSVQGTLDVTVDEEDGSVQRFQVTTAAVPFLARTGQLRYKAAVGKPRQFGGAGITPF 357 I G L VT+ E DGS Q F V ++VP L R G RY G+ R P Sbjct: 335 IYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYRSGNAQQEKPR 394 Query: 358 FGFGEAAYGLPFDITLYGGFIAASGYTSIALGVGRDFGTFGAVSADVTHARAHLWWNGAT 417 F +GLP T+YGG A Y + G+G++ G GA+S D+T A + L + + Sbjct: 395 FFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQANSTL-PDDSQ 453 Query: 418 RNGNSYRINYSKHFDGLDADVRFFGYRFSEREYTNFAQFSGDPTAYGL------------ 465 +G S R Y+K + +++ GYR+S Y NFA + Sbjct: 454 HDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGVIQVKP 513 Query: 466 ---------ANSKQRYSATMSKRFGDTST-YFSYDQTTYW-ARASEQRVGLTLTRAFSIG 514 N + + T++++ G TST Y S TYW +++ L AF Sbjct: 514 KFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSNVDEQFQAGLNTAF--- 570 Query: 515 ALRNLNVSVSAFRTQSAGASGNQFSVTATLPIGGRHTVTSNLTTGSGSTSMNAGYIYDDP 574 ++N ++S T++A G + + I H + S+ + S + +D Sbjct: 571 --EDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSMSHDLN 628 Query: 575 AGRT----------------YQINAGATDGRASANASFRQRTSTYQ-----LSAQASTLA 613 T Y + G G + S T Y+ + S + Sbjct: 629 GRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIGYSH-S 687 Query: 614 NAYAAASLEVDGSLVATQYGVSAHANGNAGDTRLLVSTDGVPDVPLS-GTLTHTDSRGYA 672 + V G ++A GV+ DT +LV G D + T TD RGYA Sbjct: 688 DDIKQLYYGVSGGVLAHANGVTLGQPL--NDTVVLVKAPGAKDAKVENQTGVRTDWRGYA 745 Query: 673 VLDGISPYNVYDATVNVEKLPLEVQVSNPIQRMVLTDGAIGFVKFSAARGSNLYLTLTDV 732 VL + Y ++ L V + N + +V T GAI +F A G L +TLT Sbjct: 746 VLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKLLMTLTH- 804 Query: 733 AGKPLPFGASVQDAANGKELGIVGEAGAAFLTQVQPKSALVVRAGERT--LCAVN-ALPN 789 KPLPFGA V + + GIV + G +L+ + + V+ GE C N LP Sbjct: 805 NNKPLPFGAMVTS-ESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCVANYQLPP 863 Query: 790 QLQLEG-TPIPVTCQ 803 + Q + T + C+ Sbjct: 864 ESQQQLLTQLSAECR 878
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.9 bits (64), Expect = 0.030 Identities = 12/23 (52%), Positives = 13/23 (56%) Query: 35 VTALCGPNGCGKSTLLRTLAGLQ 57 L G G GKSTL+ TL GL Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLD 620
>2FE2SRDCTASE#Ferric iron reductase signature. Length = 262 Score = 76.2 bits (187), Expect = 2e-18 Identities = 57/198 (28%), Positives = 87/198 (43%), Gaps = 16/198 (8%) Query: 58 DAMVRHYGGDPAQHARALMSQWSKYYFGRAAPAGVVAALTLGRPLDMAPERTFVAL-DDG 116 D + R+ ++ + L+S W+++Y G P ++A LT + LD++PE + G Sbjct: 75 DHIYRNQPMMIREN-KPLISLWAQWYIGLMVPPLMLALLTQEKALDVSPEHFHAEFHETG 133 Query: 117 MPAALYF--APDALGAPCSEPAPRYAGLVAHLGEVIDLLAAMGRVTPRVLWSNAGNLLDY 174 A + D P S + L V+ L A G + +++WSN G L+++ Sbjct: 134 RVACFWVDVCEDKNATPHSPQHRMETLISQALVPVVQALEATGEINGKLIWSNTGYLINW 193 Query: 175 LLDTY--RLLPCVADPVRDADWLFGASCVHGEPNPLRLPVRDAVPRSPLLPTPFRARRVC 232 L L + +R A F + +GE NPL R V R LL RR C Sbjct: 194 YLTEMKQLLGEATVESLRHA-LFFEKTLTNGEDNPL---WRTVVLRDGLL-----VRRTC 244 Query: 233 CLRYEIPGETQLCGSCPL 250 C RY +P Q CG C L Sbjct: 245 CQRYRLPD-VQQCGDCTL 261
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 111 bits (279), Expect = 1e-30 Identities = 68/272 (25%), Positives = 114/272 (41%), Gaps = 15/272 (5%) Query: 67 PQRVVALDFMFAESVIALDLVPVGMADTALYPGWLGYGSDRLAHVTDIGSRQEPGLEAIA 126 P R+VAL+++ E ++AL +VP G+ADT Y W+ V D+G R EP LE + Sbjct: 35 PNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSEPP-LPDSVIDVGLRTEPNLELLT 93 Query: 127 AVKPDLIIGVGFRHAPIFAALDRIAPTILFQFSPNVSEDGVPVTQLDWMREIFRTIGAVT 186 +KP ++ + P L RIAP F FS L R+ + + Sbjct: 94 EMKPSFMVW-SAGYGPSPEMLARIAPGRGFNFSDGKQ-------PLAMARKSLTEMADLL 145 Query: 187 GRDARAKAIDAQLDAGIARNAARLTAAGRSGERIALLQDLGLPDRYWAYTGNSTSAGLAR 246 + A+ AQ + I R + G R LL L P + NS + Sbjct: 146 NLQSAAETHLAQYEDFIRSMKPRFV---KRGARPLLLTTLIDPRHMLVFGPNSLFQEILD 202 Query: 247 ALGLE-PWPKKPTREGTLYVTSADLLRQRDLAVLFVTATGMDVPLSSKLDSPVWRFVPAL 305 G+ W + G+ V+ L +D+ VL + + + +P+W+ +P + Sbjct: 203 EYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNSKD-MDALMATPLWQAMPFV 261 Query: 306 RDHRIALIERNIWGFGGPMSALKLADVMTDTM 337 R R + +W +G +SA+ V+ + + Sbjct: 262 RAGRFQRVP-AVWFYGATLSAMHFVRVLDNAI 292
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 32.0 bits (72), Expect = 0.005 Identities = 15/35 (42%), Positives = 20/35 (57%) Query: 237 AIHAGDAPNVIPDRAQMRLSVRALKPEVRDLLEAR 271 AI+ P+V PD A ++ L PE RDLL+ R Sbjct: 227 AINQEPVPHVQPDIATTTTDIQGLPPEARDLLDER 261
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 42.1 bits (99), Expect = 2e-06 Identities = 36/178 (20%), Positives = 57/178 (32%), Gaps = 20/178 (11%) Query: 7 PRARAVFPFAALVAQQP-----LQQALLLAAIDPSLGGVLVSGPRGTAKSTAARALAELL 61 LV + + L D + ++++G GT K ARAL + Sbjct: 128 KLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLT---LMITGESGTGKELVARALHDYG 184 Query: 62 P--EGEFVTLPLSASDEQVTGTLDLAHALAA--NGVRFRPGLLARAHRGVLYVDEVNLLA 117 G FV + ++A + + H A G +A G L++DE+ + Sbjct: 185 KRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMP 244 Query: 118 DGLVDTLLDVAASGVNVVERDGVSHAH--DARFVLVGTMNPE----EGELRPQLLDRF 169 LL V G G D R V + + +G R L R Sbjct: 245 MDAQTRLLRVLQQG--EYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRL 300
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 31.0 bits (70), Expect = 0.007 Identities = 23/125 (18%), Positives = 45/125 (36%), Gaps = 4/125 (3%) Query: 40 GIGDGAASLLTTIPILLMGVGALSARRLQRVTGIAGGVWLGVVLIGFAC-ASRIGAQHAW 98 + + + T +L +G +L GI + G+++ F +G Sbjct: 45 NKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFS 104 Query: 99 VLLASACCAGIGIAMVQALLPGFVKAHFATRI--GGAMGVYSTSIMGGAVLASVVAPFAA 156 +L+ + G G A AL+ V A + + G A G+ + + G + + A Sbjct: 105 LLIMARFIQGAGAAAFPALVMVVV-ARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIA 163 Query: 157 ARWGW 161 W Sbjct: 164 HYIHW 168
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 29.3 bits (65), Expect = 0.014 Identities = 21/74 (28%), Positives = 34/74 (45%), Gaps = 6/74 (8%) Query: 88 FESGAILLYLADKTGQLIPKDAAGRYETIQWVMFQMGGIGP----MFGQVGFFHKFAGRD 143 +E G D G + D G+ IQ QMG + + G +G+ +F+G Sbjct: 45 YEPGGKYHLFGDPRGSV--SDRTGKINVIQDYTHQMGNLLIQQANINGTIGYHTRFSGHG 102 Query: 144 YEDKRPRDRYAAES 157 +E+ P D +AA+S Sbjct: 103 HEEHAPFDNHAADS 116
>NEISSPPORIN#Neisseria sp. porin signature. Length = 348 Score = 61.9 bits (150), Expect = 8e-13 Identities = 101/408 (24%), Positives = 147/408 (36%), Gaps = 94/408 (23%) Query: 1 MKTKLAALAALAGCSAFAHAQSSFTLYGVVDTGLLYQSTSAASFRPNAPNTGKVFRMKDG 60 MK L AL A A A + TLYG + G+ ++R GKV +++ G Sbjct: 1 MKKSLIALTLAALPVA---AMADVTLYGAIKAGV-------QTYRSVEHTDGKVSKVETG 50 Query: 61 ---GIYSSFWGIKGSEDLGGGYKVNFKL-QGSFDSGTGRLQLSDTPGAVAIFNQIASLGV 116 + S G KG EDLG G K ++L QG+ +GT N+ + +G+ Sbjct: 51 SEIADFGSKIGFKGQEDLGNGLKAVWQLEQGASVAGTNT----------GWGNKQSFVGL 100 Query: 117 SGPFGTVTAGRQIVPMIYAMADTDVRNAQFFGSVLTAWLGLNTAAGWPATSTNGAIGALY 176 G FGT+ AG + + +T G+ + AW S Y Sbjct: 101 KGGFGTIRAGS----LNSPLKNT--------GANVNAWESGKFTGNVLEISGMAQREHRY 148 Query: 177 DSNALVYQSPTFGGVSLALEYAP-------------------GGVAGQFQGGTRESVVLR 217 S + Y SP F G S +++YAP G Q+ G Sbjct: 149 LS--VRYDSPEFAGFSGSVQYAPKDNSGSNGESYHVGLNYQNSGFFAQYAG--------L 198 Query: 218 YSNYGLNASAVYYNGHDTNPAPGVAPT--------GVDNNRFVYVGAKYTVRDFSVSASY 269 + YG + Y+ + G DNN +YV +D + Y Sbjct: 199 FQRYGEGTKKIEYDDQTYSIPSLFVEKLQVHRLVGGYDNNA-LYVSVAAQQQDAKL---Y 254 Query: 270 GNGRNPAHADRVNLDMLSAGVGYRF---TPALQVASAVYYLKDRNRATNRSTAVVLTADY 326 G +H + ++A YRF TP + A D N VV+ A+Y Sbjct: 255 GAMSGNSHNSQTE---VAATAAYRFGNVTPRVSYAHGFKGTVDSANHDNTYDQVVVGAEY 311 Query: 327 SLSKRTMVYAQAGHVNNRGTMDQMLVYGQPVAPGVGTTAAMVGLRHNF 374 SKRT AG + G +V +TA+ V LRH F Sbjct: 312 DFSKRTSALVSAGWL-QGGKGADKIV----------STASAVVLRHKF 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 311 bits (798), Expect = e-101 Identities = 124/326 (38%), Positives = 175/326 (53%), Gaps = 40/326 (12%) Query: 351 ELALRVASKRLPILVLGETGAGKEVFARAIHDAGARRTRPFVAVNCGALPEALIESELFG 410 + R+ L +++ GE+G GKE+ ARA+HD G RR PFVA+N A+P LIESELFG Sbjct: 151 RVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFG 210 Query: 411 YAAGAFTGARKHGARGKIALADGGTLFLDEIGDMPLTLQTRLLRVLADGEVVPLGSDTPV 470 + GAFTGA+ G+ A+GGTLFLDEIGDMP+ QTRLLRVL GE +G TP+ Sbjct: 211 HEKGAFTGAQTRST-GRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPI 269 Query: 471 RVDLDVICATHRDLARMVADGTFREDLYYRLSGATFELPPLRERADVGDVIATVFAEEAQ 530 R D+ ++ AT++DL + + G FREDLYYRL+ LPPLR+RA+ + F ++A+ Sbjct: 270 RSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAE 329 Query: 531 ATG-HVLTLDPTLAAQLAAYPWPGNVRQLRNVLRYACAVCDAARVARRDLPADLAAQL-- 587 G V D + A+PWPGNVR+L N++R A+ + R + +L +++ Sbjct: 330 KEGLDVKRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPD 389 Query: 588 ------------------------------------GAGAAGALPDDERGRIVAALTAHR 611 L + E I+AALTA R Sbjct: 390 SPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATR 449 Query: 612 WRPDAAAKALGISRATLYRRIAKHRI 637 AA LG++R TL ++I + + Sbjct: 450 GNQIKAADLLGLNRNTLRKKIRELGV 475
>PF06776#Invasion associated locus B Length = 214 Score = 27.2 bits (60), Expect = 0.039 Identities = 11/55 (20%), Positives = 21/55 (38%), Gaps = 1/55 (1%) Query: 130 ATAPAASTPEAAAKPAKSKRASKKEKAAAAAAASADAGAGASAPAAASSTKATKG 184 PA +P A+ ++R + A A A A + + A + ++ G Sbjct: 28 QMGPAELSPMLASCRRLARRNGARLMLAGAMAI-ALSFGWSDRADAQGAVRSVHG 81
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 42.7 bits (100), Expect = 6e-06 Identities = 35/192 (18%), Positives = 73/192 (38%), Gaps = 15/192 (7%) Query: 92 KVLVEGLQRAKALSIEEQETQFSCEVMPLEPDHADSAETEALRRAIVSQFDQYVKLNKKI 151 L + L+ A S + + E A A+ E ++ K + Sbjct: 193 AELEKALEGAMNFSTADSAKIKTLEAE-KAALAARKADLEKALEGAMNFSTADSAKIKTL 251 Query: 152 PPEILTSLSGIDEAGRLADMIAERLPLKLDQKQHILEMFPVIERLEHLLAQLEAEIDILQ 211 E + E + + + + + LE A LE + +L Sbjct: 252 EAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAE---KAALEAEKADLEHQSQVLN 308 Query: 212 VEKRIRGRVKRQMEKSQREYYLNEQVKAIQKELGEGEEGAD--LEELEKRINAARMPKEA 269 R ++R ++ S+ +Q++A ++L E + ++ + L + ++A+R EA Sbjct: 309 AN---RQSLRRDLDASREAK---KQLEAEHQKLEEQNKISEASRQSLRRDLDASR---EA 359 Query: 270 KKKADAELKKLK 281 KK+ +AE +KL+ Sbjct: 360 KKQLEAEHQKLE 371 Score = 30.0 bits (67), Expect = 0.043 Identities = 29/103 (28%), Positives = 44/103 (42%), Gaps = 18/103 (17%) Query: 201 AQLEAEIDILQVEKRI----RGRVKRQMEKSQRE--------YYLNEQVKAIQKELGEGE 248 QLEAE L+ + +I R ++R ++ S+ N ++ A++K E E Sbjct: 361 KQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELE 420 Query: 249 EGADLEELEKRINAARMPKEAKK------KADAELKKLKLMSP 285 E L E EK A++ EAK K EL KL+ Sbjct: 421 ESKKLTEKEKAELQAKLEAEAKALKEKLAKQAEELAKLRAGKA 463
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.6 bits (69), Expect = 0.013 Identities = 19/113 (16%), Positives = 37/113 (32%), Gaps = 16/113 (14%) Query: 43 LCNEIIRDEAAAAGVEASLSRSDLPSPQEIRDILDQYVIGQERAKKILAVAVYNHYKRLK 102 L E A PS E ++G+ A + + Sbjct: 102 LPKPFDLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAA-----------MQEIY 150 Query: 103 HLDKKDDVELSKSNILLIGPTGSGKTLLAQTLARL---LNVPFVIADATTLTE 152 + + + + +++ G +G+GK L+A+ L N PFV + + Sbjct: 151 RVLAR--LMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPR 201
>PF05272#Virulence-associated E family protein Length = 892 Score = 27.3 bits (60), Expect = 0.015 Identities = 22/58 (37%), Positives = 28/58 (48%), Gaps = 12/58 (20%) Query: 22 AMAGVNVGINVGVPAPVYVAPAPVYAPPPPPVV-------YQPAPVYA-PAPVYAPAP 71 ++AG+ +G G PAP P PPP PVV QP P +A P + PAP Sbjct: 101 SVAGIVMGAPAGAPAP----KPPRPEPPPRPVVEKECWETIQPVPEHAVPPSFWHPAP 154
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 624 bits (1610), Expect = 0.0 Identities = 241/1068 (22%), Positives = 428/1068 (40%), Gaps = 57/1068 (5%) Query: 4 LVRLALARPYTFIVLALLILIAGPLAALRTPTDIFPDIRIPVISVVWNYAGLQPADMAGR 63 + + RP VLA+++++AG LA L+ P +P I P +SV NY G + Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 64 IVTYYERTLGTTVNDVAHIESQSFRSFGI-VKIFFQPSVDIRTATAQVTSISQTVLKQMP 122 + E+ + ++++ ++ S S + + + + FQ D A QV + Q +P Sbjct: 61 VTQVIEQNM-NGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLP 119 Query: 123 PGTTPPQILNYNASTVPVLQLALTSDTLNEQQ--LGDYATNVIRPQLLSVAGVAIPSPYG 180 I +S+ ++ SD Q + DY + ++ L + GV +G Sbjct: 120 QEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG 179 Query: 181 GKVRQVQIDLDPQALQAKGLSAQDVATALAQQNQIIPAGT------QKIGRFEYNIRLND 234 + ++I LD L L+ DV L QN I AG + +I Sbjct: 180 AQ-YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQT 238 Query: 235 SPLTIDQLNALPIRTV-NGAVIFMRDVAHVRDGFPPQGNIVRVDGRRAVLMSILKSGSAS 293 ++ + +R +G+V+ ++DVA V G I R++G+ A + I + A+ Sbjct: 239 RFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGAN 298 Query: 294 TLDIIADVKAQLPRIEATLPPSLRLVVMGDQSVFVKGAVSGVAREGLIAAALTSAMILLF 353 LD +KA+L ++ P ++++ D + FV+ ++ V + A L ++ LF Sbjct: 299 ALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLF 358 Query: 354 LGSWRSTLIIAASIPLAVLAAIAALAAAGETLNVMTLGGLALAVGILVDDATVTIENV-N 412 L + R+TLI ++P+ +L A LAA G ++N +T+ G+ LA+G+LVDDA V +ENV Sbjct: 359 LQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 418 Query: 413 WHLEQGKDVRSAILDGASQIVAPAFVSLLCICIVFVPMLLLDGVARFLFVPMAEAVIFAM 472 +E + A SQI + + VF+PM G ++ + ++ AM Sbjct: 419 VMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAM 478 Query: 473 IASFVLSRTFVPMMARYLLRPHAAHPAAVLAPHGAPFPTPRSRNPLVAFQQGFERRFAAL 532 S +++ P + LL+P +A F F F Sbjct: 479 ALSVLVALILTPALCATLLKPVSAEH----------------HENKGGFFGWFNTTFDHS 522 Query: 533 RTGYRAVLGLALAHRARFVVLFLTAVALSFVLVPGLGRNFFPSVDAGEIALHVRAPIGTR 592 Y +G L R+++++ VA VL L +F P D G ++ P G Sbjct: 523 VNHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGAT 582 Query: 593 IEETAALFDRVERTVRGVVPPRALASIVDNMGLPNSGINLTYSNSGTIGPQDGDIVVSLT 652 E T + D+V L + N+ + ++S G VSL Sbjct: 583 QERTQKVLDQVTD--------YYLKNEKANVESVFTVNGFSFSGQ---AQNAGMAFVSLK 631 Query: 653 GEHAPTAD--YVKKLRTVLPRAFPGVTFSFLPADIVSQILNFGAPAPIDVQVT---GPNL 707 D + + + F+ + I+ G D ++ G Sbjct: 632 PWEERNGDENSAEAVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGH 691 Query: 708 AANRAYATELLRRIRTVPG-VADARVQQASTYPQFTVSVDRALAAQLGITEQDVTNAVVA 766 A +LL P + R QF + VD+ A LG++ D+ + Sbjct: 692 DALTQARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTIST 751 Query: 767 SLSGTSQVSPTYWLDPHNGVSYPIVAQTPQYRMTSLSDLRALPVTGRSGAPQLLGGLATI 826 +L G + V+ G + Q D+ L V +G T Sbjct: 752 ALGG-TYVNDFI----DRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTS 806 Query: 827 VRGQTDAVVSHYDIAPLDDIFATTQ-DRDLGAVSADIERVLHASAADLPKGSRVTVRGQV 885 + Y+ P +I G A +E + A+ LP G G Sbjct: 807 HWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMALMENL----ASKLPAGIGYDWTGMS 862 Query: 886 QTMSSAFGGLLAGLAGAVLLIYLLIVVNFHSWRDAFVIVSALPAALAGIVWMLFVTRTPL 945 + A +A + ++++L + + SW ++ +P + G++ + Sbjct: 863 YQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKN 922 Query: 946 SVPALTGAILCMGVATANSILVVTFARERLAH-TADATVAALEAGFTRFRPVMMTALAMI 1004 V + G + +G++ N+IL+V FA++ + A L A R RP++MT+LA I Sbjct: 923 DVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFI 982 Query: 1005 IGMAPMALGLGDGGEQNAPLGRAVIGGLLCATVATLVFVPVVFSLVHR 1052 +G+ P+A+ G G +G V+GG++ AT+ + FVPV F ++ R Sbjct: 983 LGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRR 1030 Score = 93.0 bits (231), Expect = 4e-21 Identities = 64/358 (17%), Positives = 135/358 (37%), Gaps = 15/358 (4%) Query: 714 ATELLRRIRTVPGVADARVQQASTYPQFTVSVDRALAAQLGITEQDVTNAVVA--SLSGT 771 A+ + + + GV D VQ + +D L + +T DV N + Sbjct: 159 ASNVKDTLSRLNGVGD--VQLFGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAA 216 Query: 772 SQVSPTYWLDPHNGVSYPIVAQTPQYRMTSLSDLRALPV-TGRSGAPQLLGGLATIVRG- 829 Q+ T L P ++ I+AQT R + + + + G+ L +A + G Sbjct: 217 GQLGGTPAL-PGQQLNASIIAQT---RFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGG 272 Query: 830 QTDAVVSHYDIAP--LDDIFATTQDRDLGAVSADIERVLHASAADLPKGSRVTV-RGQVQ 886 + V++ + P I T L + I+ L P+G +V Sbjct: 273 ENYNVIARINGKPAAGLGIKLATGANAL-DTAKAIKAKLAELQPFFPQGMKVLYPYDTTP 331 Query: 887 TMSSAFGGLLAGLAGAVLLIYLLIVVNFHSWRDAFVIVSALPAALAGIVWMLFVTRTPLS 946 + + ++ L A++L++L++ + + R + A+P L G +L ++ Sbjct: 332 FVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSIN 391 Query: 947 VPALTGAILCMGVATANSILVVTFARERLAHTADATVAALEAGFTRFR-PVMMTALAMII 1005 + G +L +G+ ++I+VV + A E ++ + ++ A+ + Sbjct: 392 TLTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSA 451 Query: 1006 GMAPMALGLGDGGEQNAPLGRAVIGGLLCATVATLVFVPVVFSLVHRGDRAPHSESPS 1063 PMA G G ++ + + + L+ P + + + + A H E+ Sbjct: 452 VFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKG 509
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 40.6 bits (95), Expect = 8e-06 Identities = 18/124 (14%), Positives = 37/124 (29%), Gaps = 28/124 (22%) Query: 90 GYLHAWYVDIGAHVKGGQLLASIDTPDLDQQLQQARADLESATANE-RLAAVTAARWSEM 148 + V G V+ G +L + + + ++ L A + R ++ + Sbjct: 105 SIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNK 164 Query: 149 LAQDSVS---------------------------RQEADEKRSDLDAKRAAVAASTANVR 181 L + + + + +K +LD KRA A + Sbjct: 165 LPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARIN 224 Query: 182 RLEA 185 R E Sbjct: 225 RYEN 228 Score = 37.1 bits (86), Expect = 9e-05 Identities = 25/147 (17%), Positives = 48/147 (32%), Gaps = 4/147 (2%) Query: 117 LDQQLQQARADLESATANERLAAVTAARWSEMLAQDSVSRQEADEKRSDLDAKRAAVAAS 176 L+Q+ + A E +L + + S V++ +E L + Sbjct: 255 LEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLL 314 Query: 177 TANVRRLEALESFKRLTAPFDGVVTARKT-DVGALIDAGSGNGAELFTVSDARRLRLYVH 235 T + + E + + AP V K G ++ + V + L + Sbjct: 315 TLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAE---TLMVIVPEDDTLEVTAL 371 Query: 236 IPQDDAGAIRAGMHVALSVPERPGTTF 262 + D G I G + + V P T + Sbjct: 372 VQNKDIGFINVGQNAIIKVEAFPYTRY 398
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 25.0 bits (54), Expect = 0.047 Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 6/72 (8%) Query: 15 IALPGRAAASQSAAASAPQTLASTAPARASSRDAWNAPPVTPLARAQVYRDLVRAQRDGQ 74 A PG+AA S A S + LA + AR ++A + Y DL+R + DG Sbjct: 328 AAKPGKAAVSGDFADSYKKKLALSDSARQLYQNAKYREALD-----IHYEDLIRRKTDGS 382 Query: 75 LAQLN-RELYSH 85 +N RE+ + Sbjct: 383 SKFINGREIDAV 394
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 77.6 bits (191), Expect = 1e-18 Identities = 31/120 (25%), Positives = 49/120 (40%) Query: 2 RVLTVEDDAVTANEIVGELTARGFEVDWIDNGREGMMRAMSASYDAITLDRMLPGADGLA 61 +L +DDA + L+ G++V N + D + D ++P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 ILTAMRTVGIDTPVLMLSALGDVDERIRGLRAGGDDYLTKPFDSGELSARIEVLLRRRQA 121 +L ++ D PVL++SA I+ G DYL KPFD EL I L + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.4 bits (92), Expect = 2e-05 Identities = 72/346 (20%), Positives = 115/346 (33%), Gaps = 13/346 (3%) Query: 50 FGLALALQNLIWGIAQPLTGMIADRFGSVRVIVAGMLLYAAGLVAMAQAASIGVFTAGAG 109 +G+ LAL L+ P+ G ++DRFG V++ + A MA A + V G Sbjct: 45 YGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGR- 103 Query: 110 LVIGIALSGSAFASIYGALSRLFPPDRRGWALGVAGAIGGLGQFCMVPVAQVLIGGIGWQ 169 +V GI +G+ A ++ + D R G A G G PV L+GG Sbjct: 104 IVAGI--TGATGAVAGAYIADITDGDERARHFGFMSACFGFG-MVAGPVLGGLMGGFSPH 160 Query: 170 HAFVALAVAAALLAPLAVLVRDRPAQAASRADGTDQ-SIAAAVREAFAHRGFWLLNAGFF 228 F A A L + + R + + A+ R A L A FF Sbjct: 161 APFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFF 220 Query: 229 ACGFQLAFIATHLPAYLLDH-GLPARHASVALALIALTN-VAGTYACGHLGGLLRRKYVL 286 A + D A ++LA + + +A G + L + L Sbjct: 221 IMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRAL 280 Query: 287 --SVLYLVRALAMAAFVAAPLSPASVYVFAAVMGFTWLGTVPLTNGVISQVFGVRYIATL 344 ++ + AF + V A G +P ++S+ L Sbjct: 281 MLGMIADGTGYILLAFATRGWMAFPIMVLLASGGI----GMPALQAMLSRQVDEERQGQL 336 Query: 345 FGFVFFGHQLGSFFGVWLGALVYDATHSYLPLWIGSIALGVLAALL 390 G + L S G L +Y A+ + W + L Sbjct: 337 QGSLAALTSLTSIVGPLLFTAIYAASITTWNGWAWIAGAALYLLCL 382
>OUTRMMBRANEA#Outer membrane protein A signature. Length = 346 Score = 30.7 bits (69), Expect = 0.009 Identities = 15/96 (15%), Positives = 28/96 (29%), Gaps = 10/96 (10%) Query: 138 YAVILAGWASNSKYAFLGAMR-------AAAQMVSYEISMGFALVLVLMTAGSLNLSEIV 190 Y GW+ F+ A Y+++ + G + Sbjct: 29 YTGAKLGWSQYHDTGFINNNGPTHENQLGAGAFGGYQVNPYVGFEMGYDWLGRMPY---K 85 Query: 191 GSQQHGFFAGHGVNFLSWNWLPLLPAFVVYFVSGIA 226 GS ++G + GV + P+ +Y G Sbjct: 86 GSVENGAYKAQGVQLTAKLGYPITDDLDIYTRLGGM 121
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 95.9 bits (238), Expect = 7e-26 Identities = 68/256 (26%), Positives = 109/256 (42%), Gaps = 19/256 (7%) Query: 8 KAVLITGASRGIGRATAVLAAKRGWDV-GINYARDAAAAELTAQAVRDAGARACVVAGDV 66 K ITGA++GIG A A A +G + ++Y + E +++ A DV Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKL--EKVVSSLKAEARHAEAFPADV 66 Query: 67 ANEADVIAMFDAVTAAFGRLDALVNNAGIVAPSMPLADMPADRLRRMFDTNVLGAYLCAR 126 + A + + + G +D LVN AG++ P + + + F N G + +R Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPG-LIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 127 EAARRLSTDRGGRGGAIVNVSSIASRLGSPNEYVD-YAGSKGAVDSLTIGLAKELGPHGV 185 ++ + R G+IV V S + G P + YA SK A T L EL + + Sbjct: 126 SVSKYM---MDRRSGSIVTVGSNPA--GVPRTSMAAYASSKAAAVMFTKCLGLELAEYNI 180 Query: 186 RVNAVRPGLIETEIHAS-----GGQPGRAARLGAQ----TPLGRAGEAQEIAEAIVWLLG 236 R N V PG ET++ S G PL + + +IA+A+++L+ Sbjct: 181 RCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVS 240 Query: 237 DAASYTTGALLDVGGG 252 A + T L V GG Sbjct: 241 GQAGHITMHNLCVDGG 256
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 31.5 bits (71), Expect = 0.014 Identities = 18/84 (21%), Positives = 31/84 (36%), Gaps = 8/84 (9%) Query: 653 PPPVLKDFPAVYLTSFHLPAEQAALLDPLIARYPNLTAIDVAPILAQLQRMMLQVVGAVQ 712 P D P S+ +A LL + Y V A + ++ ++ Sbjct: 10 QMPTASDMPQ-NKVSWVPDPNRAVLLIHDMQNY------FVDAFTAGA-SPVTELSANIR 61 Query: 713 FLFGFTLAAGVLVLYTALAGSRDE 736 L + G+ V+YTA GS++ Sbjct: 62 KLKNQCVQLGIPVVYTAQPGSQNP 85
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 121 bits (304), Expect = 1e-33 Identities = 74/344 (21%), Positives = 133/344 (38%), Gaps = 39/344 (11%) Query: 28 RLFVTGGTGFIGSWLLEA-VQHANRILGSGIDVVVLSRNP--EKARAFAPHLYAVPGVEL 84 + VTG GFIG + + ++ ++++G ID + + ++AR L A PG + Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVG--IDNLNDYYDVSLKQARL---ELLAQPGFQF 56 Query: 85 HEGDVIDFDATAGTM--GAIDLCIHAATDVADIAKARDGLRVFDANVTGTRRVLDLARSN 142 H+ D+ D + G + + +A + D+N+TG +L+ R N Sbjct: 57 HKIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHN 116 Query: 143 GATRFLLTSSGAIYGQQPAMLERTPESYCGAPDTLDTQAAYGHAKRSAEWLASAYGEQHD 202 L SS ++YG M T + P +L Y K++ E +A Y + Sbjct: 117 KIQHLLYASSSSVYGLNRKMPFST-DDSVDHPVSL-----YAATKKANELMAHTYSHLYG 170 Query: 203 ISVSIARIYALVGP-GIPADGPFAAGNFIRDALAGQRIVIKGDGRPLRSYLYIADACIWL 261 + + R + + GP G P F F + L G+ I + G+ R + YI D + Sbjct: 171 LPATGLRFFTVYGPWGRPDMALF---KFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAI 227 Query: 262 LRMLH------------------GGVTGRAYNVGSERAVSILELARMVETLCDAREATVP 303 +R+ R YN+G+ V +++ + +E EA Sbjct: 228 IRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALG-IEAKKN 286 Query: 304 DMAPAPGPAPRYVPSTSLARHSLGVEEYTPLEAALTKTINWNRN 347 + PG T +G T ++ + +NW R+ Sbjct: 287 MLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRD 330
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 86.4 bits (214), Expect = 4e-21 Identities = 65/352 (18%), Positives = 115/352 (32%), Gaps = 44/352 (12%) Query: 16 RVFLTGHTGFKGSWLTLWLRSLGAEVTGY-ALAPDTTPNLFSLARVE----EGIESVIGD 70 + +TG GF G ++ L G +V G L +L AR+E G + D Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSL-KQARLELLAQPGFQFHKID 60 Query: 71 IRDRGQLLDALRRAAPEVVIHMAAQSLVRTSYSNPVETYEANVMGTVHVLDAIRQVRSVR 130 + DR + D E V + VR S NP ++N+ G +++L+ R ++ Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHN-KIQ 119 Query: 131 SVVIVTTDKCYENREWEWGYRENEAMGGYDPYSSSKGCAELVTAAYRSS---------FF 181 ++ ++ Y ++ Y+++K EL+ Y FF Sbjct: 120 HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFF 179 Query: 182 N--------EAAYDTHRVAIASARAGNVIGGGDWASD-RLIPDIIKAISAGEIVNIRNPR 232 + A A+ ++ +V G D I DI +AI I Sbjct: 180 TVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAI----IRLQDVIP 235 Query: 233 AIRPWQHVLEPLCGYLLLAEKLYVEGPRYAGAWNFGPND-IDAQPVQAIVERLTARWGDG 291 V + ++Y N G + ++ +E Sbjct: 236 HADTQWTVETGTPAASIAPYRVY----------NIGNSSPVELMDYIQALEDALGIEAKK 285 Query: 292 ARWQLDGGDHPHEATYLKLDCSKARARLGWHPRWDLDFTLDKIVDWYRAAHE 343 L GD T D +G+ P + + V+WYR ++ Sbjct: 286 NMLPLQPGDVLE--TS--ADTKALYEVIGFTPETTVKDGVKNFVNWYRDFYK 333
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 124 bits (312), Expect = 1e-36 Identities = 85/254 (33%), Positives = 135/254 (53%), Gaps = 15/254 (5%) Query: 4 LQGKRALVTGGSRGIGAAIAKRLAADGADVAITYEKSAERARAVVADIEALGRRAVAIQA 63 ++GK A +TG ++GIG A+A+ LA+ GA +A + + E+ VV+ ++A R A A A Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIA-AVDYNPEKLEKVVSSLKAEARHAEAFPA 64 Query: 64 DSADPVAVRGAVDHAAQTLGGLDILVNNAGIFRAAALDDLTLDDIDATLNVNVRAVIVAS 123 D D A+ + +G +DILVN AG+ R + L+ ++ +AT +VN V AS Sbjct: 65 DVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNAS 124 Query: 124 QAAARHL--GEGGRIVSTGSCLATRVPDAGMSLYAASKAALIGWTQGLARDLGARGITVN 181 ++ ++++ G IV+ GS VP M+ YA+SKAA + +T+ L +L I N Sbjct: 125 RSVSKYMMDRRSGSIVTVGSN-PAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 182 LVHPGSTDTDMNPA-----DGEH----AGAQRSRMAIP--QYGKAEDVAALVAFVVGPEG 230 +V PGST+TDM + +G + + IP + K D+A V F+V + Sbjct: 184 IVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 231 RSINGTGLTIDGGA 244 I L +DGGA Sbjct: 244 GHITMHNLCVDGGA 257
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 54.2 bits (130), Expect = 2e-11 Identities = 32/203 (15%), Positives = 64/203 (31%), Gaps = 15/203 (7%) Query: 1 MAERGRPRSFD-KEAALDRAMEVFWRLGYEGASMTDLTAAMGIASPSLYAAFGSKEALF- 58 MA + + + + ++ LD A+ +F + G S+ ++ A G+ ++Y F K LF Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 59 -------RQAIEHYRETEGREIWDGVEQARSAHDAIENYLMQTARVFTRRSKPAGCLIVL 111 E E + + D + R + T + I+ Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLEST------VTEERRRLLMEIIF 114 Query: 112 SALHPAERSDTVRQTLIAMREQTVAALRARLGEGVAAGEIFAHADLDAIARYYVTVQQGM 171 V+Q + ++ + L + A + A A G+ Sbjct: 115 HKCEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGL 174 Query: 172 SIQARDGASRRDLEAVAQAALAA 194 DL+ A+ +A Sbjct: 175 MENWLFAPQSFDLKKEARDYVAI 197
>cloacin#Cloacin signature. Length = 551 Score = 27.0 bits (59), Expect = 0.017 Identities = 22/72 (30%), Positives = 27/72 (37%), Gaps = 1/72 (1%) Query: 36 GYAYGPAYGAAPVYGTVNIWGGGGGGRDWDRGHRDYRRWDRDRGDHGGWGRGGGRR-GDW 94 G+ G + + G G GGG D + W G WG G G G Sbjct: 8 GHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGG 67 Query: 95 NEGAGGGRGDGG 106 N +GGG G GG Sbjct: 68 NGNSGGGSGTGG 79
>SYCECHAPRONE#Gram-negative bacterial type III secretion SycE chaperone signature. Length = 130 Score = 25.4 bits (55), Expect = 0.011 Identities = 8/28 (28%), Positives = 16/28 (57%) Query: 18 KPTLEAEQRKGRSLLWDKQPIDLDERAE 45 KP L ++ G +LW++QP++ + Sbjct: 75 KPILSWDEVGGHPVLWNRQPLNSLDNNS 102
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 44.6 bits (105), Expect = 2e-07 Identities = 37/174 (21%), Positives = 66/174 (37%), Gaps = 7/174 (4%) Query: 47 AQRVISLAPHATELVYAAG----GGAKLVGTVTYSDYPPAAQAVPRVGDNKALDLERIAA 102 R+++L EL+ A G G A + + PP +V VG +LE + Sbjct: 35 PNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTE 94 Query: 103 LKPDLIVV-WRHGNAERQTDALRALHIPLFFSEPKHLDDVATSLRQIGTLLGTAPVADAA 161 +KP +V +G + + F + L SL ++ LL A+ Sbjct: 95 MKPSFMVWSAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNLQSAAETH 154 Query: 162 AASFSRDIAALRARYAARA--PVTMFFQVWDRPLTTLNGAHLFNEVITLCGGRN 213 A + I +++ R+ R P+ + + R + LF E++ G N Sbjct: 155 LAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYGIPN 208
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 107 bits (269), Expect = 2e-30 Identities = 79/249 (31%), Positives = 121/249 (48%), Gaps = 12/249 (4%) Query: 6 QVALVTGSSRGIGAEIARRLARDGFRVVVNYAGGAGPAREVVDAIAADGGEAIAVQADIA 65 ++A +TG+++GIG +AR LA G + +VV ++ A+ A A AD+ Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAA-VDYNPEKLEKVVSSLKAEARHAEAFPADVR 67 Query: 66 DPAAVAALFEAAEQAFGRIDVVVNSAGVMKLGAIADYDDTTFDQTVAINLKGTFNVSREA 125 D AA+ + E+ G ID++VN AGV++ G I D ++ T ++N G FN SR Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 126 AK--RVRSGGRIVNLSSTMVGVRLPTYGVYVATKAAVEGLTQVLAQEMRGRGISVNAVAP 183 +K R G IV + S GV + Y ++KAA T+ L E+ I N V+P Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 184 GPVATE----LFLEGKSPEQVDR--LAKMN---PLERLGQPADIAGVVAFLAGPDGAWVN 234 G T+ L+ + EQV + L PL++L +P+DIA V FL + Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHIT 247 Query: 235 GQILRANGG 243 L +GG Sbjct: 248 MHNLCVDGG 256
>cloacin#Cloacin signature. Length = 551 Score = 47.0 bits (111), Expect = 7e-08 Identities = 31/79 (39%), Positives = 36/79 (45%), Gaps = 1/79 (1%) Query: 255 GGNGGGHGGGSGGGNGGGNGG-GHGGGNGGGNGGGNGGGNGGGNGGGNGGGSGGGNGGGS 313 GG+G GH G+ +G NGG G GG + G GGG+G G G G G Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGH 62 Query: 314 GGGSGGGNGGGHGGGNGGG 332 G G G GN GG G G Sbjct: 63 GNGGGNGNSGGGSGTGGNL 81 Score = 45.5 bits (107), Expect = 2e-07 Identities = 33/80 (41%), Positives = 39/80 (48%) Query: 142 SGTSGGGTSGGGTSSGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSG 201 SG G G + G S+ G GG +G G GG + G G S GG SG G GG SG Sbjct: 2 SGGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSG 61 Query: 202 GGTSGGGTSGGGTSGGGTSG 221 G GG + GG SG G + Sbjct: 62 HGNGGGNGNSGGGSGTGGNL 81 Score = 45.1 bits (106), Expect = 3e-07 Identities = 36/82 (43%), Positives = 40/82 (48%), Gaps = 1/82 (1%) Query: 271 GGNGGGHGGGNGGGNGGGNGGGNGGGNGGGNGGGSG-GGNGGGSGGGSGGGNGGGHGGGN 329 GG+G GH G +G NGG G G GGG GSG GGGSG G G G G+ Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGH 62 Query: 330 GGGHGGGNGGGSSGGSTGGHGI 351 G G G GN GG SG + Sbjct: 63 GNGGGNGNSGGGSGTGGNLSAV 84 Score = 44.7 bits (105), Expect = 4e-07 Identities = 29/81 (35%), Positives = 35/81 (43%) Query: 225 GHGGGGHGDGGGNGGGNGVGNGGGNGGGHGGGNGGGHGGGSGGGNGGGNGGGHGGGNGGG 284 G G GH G + GN G G G G G +G G + GG G H GG G Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGH 62 Query: 285 NGGGNGGGNGGGNGGGNGGGS 305 GG G +GGG+G G + Sbjct: 63 GNGGGNGNSGGGSGTGGNLSA 83 Score = 44.7 bits (105), Expect = 5e-07 Identities = 32/79 (40%), Positives = 38/79 (48%) Query: 138 GTSGSGTSGGGTSGGGTSSGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGG 197 G G G + G S G +GG +G G GG + G G S GG SG G GG SG Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGH 62 Query: 198 GTSGGGTSGGGTSGGGTSG 216 G GG + GG SG G + Sbjct: 63 GNGGGNGNSGGGSGTGGNL 81 Score = 43.9 bits (103), Expect = 7e-07 Identities = 35/83 (42%), Positives = 41/83 (49%), Gaps = 1/83 (1%) Query: 183 GTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGHGGHGGGGHGDGGGNGGGNG 242 G G G + G S G GG +G G GG + G G S + GGG G G GGG+G Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGG-SGSGIHWGGGSG 61 Query: 243 VGNGGGNGGGHGGGNGGGHGGGS 265 GNGGGNG GG GG+ Sbjct: 62 HGNGGGNGNSGGGSGTGGNLSAV 84 Score = 43.9 bits (103), Expect = 8e-07 Identities = 32/79 (40%), Positives = 35/79 (44%) Query: 163 GTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGG 222 G G G + G S G GG +G G GG + G G S GG SG G GG SG Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGH 62 Query: 223 HGGHGGGGHGDGGGNGGGN 241 G G G G G G GG Sbjct: 63 GNGGGNGNSGGGSGTGGNL 81 Score = 43.5 bits (102), Expect = 9e-07 Identities = 29/79 (36%), Positives = 34/79 (43%) Query: 173 GTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGHGGHGGGGHG 232 G G G + G S G GG +G G GG + G G S GG SG GGG Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGH 62 Query: 233 DGGGNGGGNGVGNGGGNGG 251 GG G +G G+G G Sbjct: 63 GNGGGNGNSGGGSGTGGNL 81 Score = 43.5 bits (102), Expect = 9e-07 Identities = 27/80 (33%), Positives = 34/80 (42%) Query: 238 GGGNGVGNGGGNGGGHGGGNGGGHGGGSGGGNGGGNGGGHGGGNGGGNGGGNGGGNGGGN 297 G G G G + G+ G G G G G +G G + GG G + GG G Sbjct: 4 GDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHG 63 Query: 298 GGGNGGGSGGGNGGGSGGGS 317 GG G SGGG+G G + Sbjct: 64 NGGGNGNSGGGSGTGGNLSA 83 Score = 43.5 bits (102), Expect = 1e-06 Identities = 32/78 (41%), Positives = 37/78 (47%) Query: 148 GTSGGGTSSGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGG 207 G G G ++G S G GG +G G GG + G G S GG SG G GG SG Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGH 62 Query: 208 GTSGGGTSGGGTSGGHGG 225 G GG + GG SG G Sbjct: 63 GNGGGNGNSGGGSGTGGN 80 Score = 43.5 bits (102), Expect = 1e-06 Identities = 32/79 (40%), Positives = 37/79 (46%) Query: 128 GTSGGGTSGGGTSGSGTSGGGTSGGGTSSGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGG 187 G G G + G S SG GG +G G G + G G S GG SG G GG SG Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGH 62 Query: 188 GTSGGGTSGGGTSGGGTSG 206 G GG + GG SG G + Sbjct: 63 GNGGGNGNSGGGSGTGGNL 81 Score = 43.2 bits (101), Expect = 1e-06 Identities = 30/81 (37%), Positives = 32/81 (39%) Query: 205 SGGGTSGGGTSGGGTSGGHGGHGGGGHGDGGGNGGGNGVGNGGGNGGGHGGGNGGGHGGG 264 SGG G T TSG G G GG + G GGG G G G G G Sbjct: 2 SGGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSG 61 Query: 265 SGGGNGGGNGGGHGGGNGGGN 285 G G G GN GG G G + Sbjct: 62 HGNGGGNGNSGGGSGTGGNLS 82 Score = 43.2 bits (101), Expect = 1e-06 Identities = 34/80 (42%), Positives = 39/80 (48%), Gaps = 1/80 (1%) Query: 158 GTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGG 217 G G G + G S G GG +G G GG + G G S GG SG G GG SG Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGH 62 Query: 218 GTSGGHGGHGGGGHGDGGGN 237 G +GG G+ GGG G GG Sbjct: 63 G-NGGGNGNSGGGSGTGGNL 81 Score = 43.2 bits (101), Expect = 1e-06 Identities = 33/84 (39%), Positives = 44/84 (52%) Query: 307 GGNGGGSGGGSGGGNGGGHGGGNGGGHGGGNGGGSSGGSTGGHGIGGHGNGGGNGNGNGN 366 GG+G G G+ +G +GG G G GGG GS S GG G+G G G+G+ Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGH 62 Query: 367 GGTGSGGANGVGNGSGGGGSGGSA 390 G G G +G G+G+GG S +A Sbjct: 63 GNGGGNGNSGGGSGTGGNLSAVAA 86 Score = 42.8 bits (100), Expect = 2e-06 Identities = 31/80 (38%), Positives = 37/80 (46%) Query: 122 NGGKGDGTSGGGTSGGGTSGSGTSGGGTSGGGTSSGGTSGGGTSGGGTSGGGTSGGGTSG 181 +GG G G + G S G G +G G GG + G S GG SG G GG SG Sbjct: 2 SGGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSG 61 Query: 182 GGTSGGGTSGGGTSGGGTSG 201 G GG + GG SG G + Sbjct: 62 HGNGGGNGNSGGGSGTGGNL 81 Score = 42.4 bits (99), Expect = 2e-06 Identities = 39/101 (38%), Positives = 43/101 (42%), Gaps = 1/101 (0%) Query: 220 SGGHG-GHGGGGHGDGGGNGGGNGVGNGGGNGGGHGGGNGGGHGGGSGGGNGGGNGGGHG 278 SGG G GH G H G GG GG G + + G G G+G GGG G Sbjct: 2 SGGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSG 61 Query: 279 GGNGGGNGGGNGGGNGGGNGGGNGGGSGGGNGGGSGGGSGG 319 GNGGGNG GG GGN G S G+GG Sbjct: 62 HGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGG 102 Score = 42.0 bits (98), Expect = 3e-06 Identities = 31/79 (39%), Positives = 34/79 (43%), Gaps = 1/79 (1%) Query: 168 GTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTS-GGHGGH 226 G G G + G S G GG +G G GG + G G S GG SG G GG GH Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGH 62 Query: 227 GGGGHGDGGGNGGGNGVGN 245 G GG G G G G Sbjct: 63 GNGGGNGNSGGGSGTGGNL 81 Score = 41.6 bits (97), Expect = 5e-06 Identities = 31/76 (40%), Positives = 35/76 (46%) Query: 121 GNGGKGDGTSGGGTSGGGTSGSGTSGGGTSGGGTSSGGTSGGGTSGGGTSGGGTSGGGTS 180 G G S G GG +G G GG + G G SS GG SG G GG SG G Sbjct: 6 GRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNG 65 Query: 181 GGGTSGGGTSGGGTSG 196 GG + GG SG G + Sbjct: 66 GGNGNSGGGSGTGGNL 81 Score = 41.2 bits (96), Expect = 5e-06 Identities = 33/96 (34%), Positives = 42/96 (43%), Gaps = 7/96 (7%) Query: 283 GGNGGGNGGGNGGGNGGGNGGGSGGGNGGGSGGGSGGGNGGGHGGGNGGGHGGGNGGGSS 342 GG+G G+ G +G NGG +G G GGG+ GSG + GGG+G G Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSS-------ENNPWGGGSGSGIH 55 Query: 343 GGSTGGHGIGGHGNGGGNGNGNGNGGTGSGGANGVG 378 G GHG GG G G+G G + G Sbjct: 56 WGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFG 91 Score = 39.7 bits (92), Expect = 1e-05 Identities = 38/113 (33%), Positives = 46/113 (40%), Gaps = 2/113 (1%) Query: 108 GPAGVSGSPGSTSGNGGKGDGTSGGGTSGGGTSGSGTSGGGTSGGGTSSGGTSGGGTSGG 167 G G + G+ S +G G +G G GG + GSG S GG S G GG SG Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGH 62 Query: 168 GTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTS 220 G GG + GG SG G G ++ G T G G S G S Sbjct: 63 GNGGGNGNSGGGSGTG--GNLSAVAAPVAFGFPALSTPGAGGLAVSISAGALS 113 Score = 39.7 bits (92), Expect = 2e-05 Identities = 33/79 (41%), Positives = 41/79 (51%), Gaps = 1/79 (1%) Query: 315 GGSGGGNGGGHGGGNGGGHGGGNGGGSSGGSTGGHGIGGHGNGGGNGNGNGNG-GTGSGG 373 GG G G+ G +G +GG G G GG++ G G N G G+G+G G GSG Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGH 62 Query: 374 ANGVGNGSGGGGSGGSAGG 392 NG GNG+ GGGSG Sbjct: 63 GNGGGNGNSGGGSGTGGNL 81 Score = 38.5 bits (89), Expect = 4e-05 Identities = 36/112 (32%), Positives = 47/112 (41%), Gaps = 2/112 (1%) Query: 89 GGGSPGNSGNGGSGGSGAVGPAGVSGSPGSTSGNGGKGDGTSGGGTSGGGTSGSGTSGGG 148 G G N+G + G+ GP G+ G++ G+G + GG SG G G SG G Sbjct: 4 GDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHG 63 Query: 149 TSGGGTSSGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTSGGGTS 200 GG +SGG SG G G ++ G T G G S G S Sbjct: 64 NGGGNGNSGGGSGTG--GNLSAVAAPVAFGFPALSTPGAGGLAVSISAGALS 113 Score = 33.9 bits (77), Expect = 0.001 Identities = 28/72 (38%), Positives = 33/72 (45%), Gaps = 3/72 (4%) Query: 327 GGNGGGHGGG---NGGGSSGGSTGGHGIGGHGNGGGNGNGNGNGGTGSGGANGVGNGSGG 383 GG+G GH G G +GG TG GG +G G + N G GSG G GSG Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGH 62 Query: 384 GGSGGSAGGHGH 395 G GG+ G Sbjct: 63 GNGGGNGNSGGG 74 Score = 32.8 bits (74), Expect = 0.002 Identities = 30/103 (29%), Positives = 38/103 (36%) Query: 78 GATGSGAGNTTGGGSPGNSGNGGSGGSGAVGPAGVSGSPGSTSGNGGKGDGTSGGGTSGG 137 S +GN GG + G G S GSG G + + G G G GG +G Sbjct: 11 TGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGN 70 Query: 138 GTSGSGTSGGGTSGGGTSSGGTSGGGTSGGGTSGGGTSGGGTS 180 GSGT G ++ + G T G G S G S Sbjct: 71 SGGGSGTGGNLSAVAAPVAFGFPALSTPGAGGLAVSISAGALS 113
>PF06872#EspG protein Length = 398 Score = 31.2 bits (70), Expect = 0.008 Identities = 31/121 (25%), Positives = 52/121 (42%), Gaps = 22/121 (18%) Query: 145 DGAALDTALAEAGLCAALIRTPDE------WAAHDQARALASLPLFEIERIGDAPVEAIG 198 DG++L ++ + L A I TP+ A++Q R L SLP I R P + Sbjct: 101 DGSSLRISVTNSELIEAEIHTPNNEKFLVLLEANEQNRLLQSLP---INR--HMPYIQVH 155 Query: 199 RGEPDQPLAGV----RVLDLTRIIAGPVAGRTLASHGAQTLLVNGPHLPNIASLVIDNGR 254 P + L + ++L T ++ TL H QT ++G +++ +D R Sbjct: 156 HTLPQEELTDLLSMHKLLSFTSKLSA-----TLIPHNNQTDPLSGL--TPFSTVFMDTSR 208 Query: 255 G 255 G Sbjct: 209 G 209
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 140 bits (354), Expect = 7e-39 Identities = 92/408 (22%), Positives = 175/408 (42%), Gaps = 15/408 (3%) Query: 17 VMLWLVATGFFMQTLDATIVNTALPSMAVSLGESPLRMQSVVIAYSLTMAVMIPVSGWLA 76 +++WL FF L+ ++N +LP +A + P V A+ LT ++ V G L+ Sbjct: 15 ILIWLCILSFF-SVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLS 73 Query: 77 DTFGTRRVFFSAILVFSLGSLLCANAHTLQQLVVF-RVVQGVGGAMLLPVGRLAVLRTFP 135 D G +R+ I++ GS++ H+ L++ R +QG G A + + V R P Sbjct: 74 DQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIP 133 Query: 136 AERYLSALSFVAIPGLIGPLIGPTLGGWLVKIASWHWIFLINVPVGVTGCIATFYSMPDS 195 E A + +G +GP +GG + HW +L+ +P+ + + Sbjct: 134 KENRGKAFGLIGSIVAMGEGVGPAIGGMIAH--YIHWSYLLLIPMITIITVPFLMKLLKK 191 Query: 196 RNPAVGRFDLKGYLLLTIGMVAISLSLDGLADLGMQHAAVLVLLILSLACFVAYGLYAVR 255 G FD+KG +L+++G+V L + L++ +LS FV + + Sbjct: 192 EVRIKGHFDIKGIILMSVGIVFFMLFTT------SYSISFLIVSVLSFLIFVKHIR---K 242 Query: 256 APQPIFSLELFKIHTFSVGLLGNLFARIGSGAMPYLIPLLLQVSLGYSAFEAG-LMMLPV 314 P L K F +G+L ++P +++ S E G +++ P Sbjct: 243 VTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPG 302 Query: 315 AAAGMFSKRIITQLITRHGYRKVLLVNTIMVGVMMASFALMRDTVPVWVKVVHLALFGGF 374 + + I L+ R G VL + + V + + + +T ++ ++ + + GG Sbjct: 303 TMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGL 362 Query: 375 NSMQFTAMNTLTLKDLGTGGASSGNSLFSLVQMLSMSLGVTVAGALLA 422 + + T ++T+ L A +G SL + LS G+ + G LL+ Sbjct: 363 SFTK-TVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 74.3 bits (182), Expect = 6e-18 Identities = 55/199 (27%), Positives = 75/199 (37%), Gaps = 16/199 (8%) Query: 3 IRGNVFLITGGASGLGAGTARMLAQAGGKVVLADLNEAAGMALAHELGGVFVRCD----- 57 I G + ITG A G+G AR LA G + D N + L + Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 58 -VSSEADAQAAVDAATRAGTLRGLVNCAGIAPAAKTVGKDGAHPLDVFAKTINVNLVGTF 116 S A + G + LVN AG+ G + + + T +VN G F Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVL----RPGLIHSLSDEEWEATFSVNSTGVF 121 Query: 117 NMIRLAAAAMAATTPNDGGERGVIVSTASVAAYDGQIGQAAYAASKAGVAGMTLPIARDL 176 N R + M G IV+ S A + AAYA+SKA T + +L Sbjct: 122 NASRSVSKYMMDR------RSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLEL 175 Query: 177 ARQGIRVMTIAPGLFETPM 195 A IR ++PG ET M Sbjct: 176 AEYNIRCNIVSPGSTETDM 194
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 28.9 bits (64), Expect = 0.046 Identities = 28/111 (25%), Positives = 40/111 (36%), Gaps = 4/111 (3%) Query: 6 TRRNTPPQRQQRDEADGSHADGQFDLFGAPPDDARAAAAPSDDDSPAGARDRVTTGEHDA 65 T RN P + S + D+ P D +A + + P V+ E+ A Sbjct: 282 TDRNGNPVQVVATFGRDSQGNTTVDVQVIPRPDLTPGSAEAPNAQPL---PEVSPAENPA 338 Query: 66 AQPAKSPARAGRASPRPSSDQEPEP-PPASGLLWDEPLPPATPPKKGRRQR 115 PA + R +P P D P+ P G P PA P + R R Sbjct: 339 NNPAPNENPGTRPNPEPDPDLNPDANPDTDGQPGTRPDSPAVPDRPNGRHR 389
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 41.3 bits (97), Expect = 5e-06 Identities = 50/211 (23%), Positives = 78/211 (36%), Gaps = 10/211 (4%) Query: 31 VLLAALAIVLDGFDGQLIGFAIPVLIREWGITRGA---FAPAVAAGLIGMGIGSACAGIV 87 +++ + LD LI +P L+R+ + + +A + + G + Sbjct: 7 LIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGAL 66 Query: 88 ADRFGRRQAVIGSVFLFGVATCAIGFAPDVATIAMLRFCAGLGIGGALPTATTMTAEYTP 147 +DRFGRR ++ S+ V + AP + + + R AG+ G A A+ T Sbjct: 67 SDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGI-TGATGAVAGAYIADITD 125 Query: 148 ARRRTMMVTATIVCVPLGGMLAGLFAHEVLPRYGWRGLFFAGGALPLVLGFVLVRALPES 207 R C GM+AG ++ + FFA AL L F+ L Sbjct: 126 GDERARHFGFMSACFGF-GMVAGPVLGGLMGGFSPHAPFFAAAALNG-LNFLTGCFLLPE 183 Query: 208 PRYLARRPARWPELGAL----LARMQRPVAP 234 RRP R L L AR VA Sbjct: 184 SHKGERRPLRREALNPLASFRWARGMTVVAA 214
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 31.5 bits (71), Expect = 5e-04 Identities = 13/54 (24%), Positives = 22/54 (40%) Query: 34 HIPRAVYPYSAKPLTRPVTVLVRALMTTAGEAQNVTVTTSSRNAAADRAAVDAM 87 + YP A+ L V V+ +T G NV + ++ +R +AM Sbjct: 157 SRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAM 210
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 36.8 bits (85), Expect = 1e-05 Identities = 17/67 (25%), Positives = 32/67 (47%), Gaps = 5/67 (7%) Query: 28 RPAGFTLIELMIVLAIVGVIAAYAIPAYQDYLARSRVGEGLALASSARLAVADNAASGAG 87 + GFTL+E+M+V+ I+GV+A+ +P + + + + +NA Sbjct: 6 KQRGFTLLEIMVVIVIIGVLASLVVPNLM-----GNKEKADKQKAVSDIVALENALDMYK 60 Query: 88 LDGGYSP 94 LD + P Sbjct: 61 LDNHHYP 67
>TYPE3IMPPROT#Type III secretion system inner membrane P protein family signature. Length = 224 Score = 28.6 bits (64), Expect = 0.046 Identities = 16/89 (17%), Positives = 27/89 (30%), Gaps = 9/89 (10%) Query: 266 LDAMRDELREHWRKNADPYNAKPLNATPLAQQIARDQLELVWAPAEFKVDAPDKIARPTD 325 +D D R++ K +D L Q QL+ + V Sbjct: 92 VDEGLDGYRDYLIKYSDR---------ELVQFFENAQLKRQYGEETETVKRDKDEIEKPS 142 Query: 326 AYVSPPMQRLGELTRGARKEFLAFSPYFV 354 + P L E+ + F + P+ V Sbjct: 143 IFALLPAYALSEIKSAFKIGFYLYLPFVV 171
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 103 bits (259), Expect = 5e-29 Identities = 71/247 (28%), Positives = 110/247 (44%), Gaps = 14/247 (5%) Query: 3 ALVTGGSGALGQAICMALAQAGHEVWVHANRNLAQAQTVAQQIAAAGGTAHAIAFDVTDG 62 A +TG + +G+A+ LA G + + N + + V + A A A DV D Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHI-AAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDS 69 Query: 63 DATLAALAPFVDD-APVQILVNNAGIHDDAPMAGMSRRQWHSVIDVTLDGFFNVTQPLLL 121 A A + P+ ILVN AG+ + +S +W + V G FN ++ + Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSK 129 Query: 122 PMIRTRRGRIVNIASVAGVTGNRGQVNYAAAKAGLIGATKSLSLELASRGITVNAVAPGI 181 M+ R G IV + S YA++KA + TK L LELA I N V+PG Sbjct: 130 YMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGS 189 Query: 182 IESPM-----ADHAFPAERIRQL-------VPAQRAGRPDEVAAMVAYLVSDAAAYVTGQ 229 E+ M AD + I+ +P ++ +P ++A V +LVS A ++T Sbjct: 190 TETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITMH 249 Query: 230 VLSVNGG 236 L V+GG Sbjct: 250 NLCVDGG 256
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 29.4 bits (66), Expect = 0.009 Identities = 19/94 (20%), Positives = 37/94 (39%), Gaps = 9/94 (9%) Query: 103 QPLRAIFRQSVIGNLMNPKVTLFFVVFL-----PQFVDPHGAQGVTLQMFE---LGALFM 154 Q +R+ +Q++I + V + V L P+ V+ L + +G Sbjct: 163 QQMRSRIQQAMIYPCVLTVVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDA 222 Query: 155 LQTAAIFSLFGVGAGAIGA-WLKRRPKAGVWLDR 187 ++T + L + AG + + R+ K V R Sbjct: 223 VRTFGPWMLLALLAGFMAFRVMLRQEKRRVSFHR 256
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 31.8 bits (72), Expect = 0.004 Identities = 17/102 (16%), Positives = 28/102 (27%), Gaps = 1/102 (0%) Query: 454 PDDPDLRYDYAMAAEKTGHYATMEKQLRELIRTQPDNPQAYNALGYSLADRNQRLPEASK 513 D + Y A ++G Y K + L + + + LG Q A Sbjct: 33 SDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQ-YDLAIH 91 Query: 514 LIDKALSLAPNDAYIMDSLGWVKYRMGDTTGAAKVLQRAFEL 555 + + + G+ A L A EL Sbjct: 92 SYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQEL 133 Score = 31.1 bits (70), Expect = 0.007 Identities = 21/112 (18%), Positives = 37/112 (33%), Gaps = 5/112 (4%) Query: 478 KQLRELIRTQPDNPQAYNALGYSLADRNQRLPEASKLIDKALSLAPNDAYIMDSLGWVKY 537 L E+ D + +L ++ ++ + +A K+ L D+ LG + Sbjct: 26 AMLNEIS---SDTLEQLYSLAFN-QYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQ 81 Query: 538 RMGDTTGAAKVLQRAFELQPNAEIGA-HLGEVLWKSGAQDDARIAWRAAQKL 588 MG A + H E L + G +A AQ+L Sbjct: 82 AMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQEL 133
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 519 bits (1339), Expect = e-178 Identities = 192/567 (33%), Positives = 313/567 (55%), Gaps = 7/567 (1%) Query: 296 PNTLAGVCAAPGIAVGTLVRLDDADIVPPEQASGTPASESRRLDQALKAVDAELDETVRN 355 + + G+ A+ G+A+ + ++ + + ++E +L AL+ EL Sbjct: 2 HHKITGIAASSGVAIAKAFIHLEPNVDIEKTSITDVSTEIEKLTAALEKSKEELRAIKDQ 61 Query: 356 ASARGAVGEAGIFAVHRVLLEDPTLVDAARDQI-SLGKSAGFAWRATIRAQIDTLSKLDD 414 A +A IFA H ++L+DP LVD + +I + +A +A + + +D+ Sbjct: 62 TEASMGADKAEIFAAHLLVLDDPELVDGIKGKIENEQMNAEYALKEVSDMFVSMFESMDN 121 Query: 415 ALLAERAADLRDIEKRVLRAL-GHTSGATRALPDEAVLAAEEFTPSDLSSLDRQRVTALV 473 + ERAAD+RD+ KRVL L G +G+ + +E V+ AE+ TPSD + L++Q V Sbjct: 122 EYMKERAADIRDVSKRVLGHLIGVETGSLATIAEETVIIAEDLTPSDTAQLNKQFVKGFA 181 Query: 474 MARGGATSHAAIIARQLGIPALVAVGDALYAIPDGTQVVVDASAGRLEHAPTALDVERAR 533 GG TSH+AI++R L IPA+V + I G V+VD G + PT +V+ Sbjct: 182 TDIGGRTSHSAIMSRSLEIPAVVGTKEVTEKIQHGDMVIVDGIEGIVIVNPTEEEVKAYE 241 Query: 534 HERQRLDGVREANRQMAGAAAATIDGRAIEVAANIATLDDANTAVDNGADAIGLLRTELM 593 +R + ++ ++ G + T DG +E+AANI T D + + NG + IGL RTE + Sbjct: 242 EKRAAFEKQKQEWAKLVGEPSTTKDGAHVELAANIGTPKDVDGVLANGGEGIGLYRTEFL 301 Query: 594 FIHRQSAPSAVEHQQSYQSIVDALQGRTAIIRTLDVGADKEVDYLTLPPEPNPALGLRGI 653 ++ R P+ E ++Y+ +V + G+ +IRTLD+G DKE+ YL LP E NP LG R I Sbjct: 302 YMDRDQLPTEEEQFEAYKEVVQRMDGKPVVIRTLDIGGDKELSYLQLPKELNPFLGFRAI 361 Query: 654 RLAQVRPDLLDDQLQGLLAVRPFGAVRILLPMVTDAGELVRLRKRIDEFARAQGRT---- 709 RL + D+ QL+ LL +G ++++ PM+ EL + + + E Sbjct: 362 RLCLEKQDIFRTQLRALLRASTYGNLKVMFPMIATLEELRQAKAIMQEEKDKLLSEGVDV 421 Query: 710 -EPIEVGVMIEVPSAALLADQLAQHADFLSIGTNDLTQYTLAMDRCQADLAAQSDGLHPA 768 + IEVG+M+E+PS A+ A+ A+ DF SIGTNDL QYT+A DR ++ HPA Sbjct: 422 SDSIEVGIMVEIPSTAVAANLFAKEVDFFSIGTNDLIQYTMAADRMNERVSYLYQPYHPA 481 Query: 769 VLRLIDIAVRGAAKHGKWVGVCGALGGDPLAVPILVGLGVTELSVDPVSVPGIKARVRRL 828 +LRL+D+ ++ A GKWVG+CG + GD +A+P+L+GLG+ E S+ S+ ++++ +L Sbjct: 482 ILRLVDMVIKAAHSEGKWVGMCGEMAGDEVAIPLLLGLGLDEFSMSATSILPARSQLLKL 541 Query: 829 DYQLCRQRAQDLLALDSAQAVRAASRE 855 + + AQ L LD+A+ V ++ Sbjct: 542 SKEELKPFAQKALMLDTAEEVEQLVKK 568
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 31.3 bits (70), Expect = 0.022 Identities = 43/177 (24%), Positives = 64/177 (36%), Gaps = 19/177 (10%) Query: 853 AARRIEAARAAGPFDNVDVLARRAQLERRDLEALAAANALATLAGHRRDALWQAVAAAPE 912 A+ AA A + R+A+ + R A+ AAN A A VA A Sbjct: 212 ASIEAAAANKAREQAAAEA-KRKAEEQARQQAAIRAANTYAM------PANGSVVATAAG 264 Query: 913 RDLLAAAPIDEPEKPALGAPSEADDILADYDTTGLTLNRHP-VALVRPALRAQRLSSAAE 971 R L+ A GA S A I G L P V V A +A + Sbjct: 265 RGLIQVAQ---------GAASLAQAISDAIAVLGRVLASAPSVMAVGFASLTYSSRTAEQ 315 Query: 972 LRDRSDGRLARACGIVTARQMPGTAKGVMFMTLEDETGCVNVIVRPELLARQRRETL 1028 +D++ + A G+ A+ + V + +G V++ +R AR TL Sbjct: 316 WQDQTPDSVRYALGMDAAKLGLPPS--VNLNAVAKASGTVDLPMRLTNEARGNTTTL 370
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 58.8 bits (142), Expect = 2e-11 Identities = 28/103 (27%), Positives = 41/103 (39%), Gaps = 2/103 (1%) Query: 409 APAQAASGAAEQSAAASAAAPASTALSTVYFETGKSVLPADAKAAIAAAADYAKAH--PD 466 A A + A T S V F K+ L + +AA+ D Sbjct: 193 QGEAAPVVAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKD 252 Query: 467 AKLALSGFTDKTGSADANAELAKHRAQVVRDALKAAGVAEDHI 509 + + G+TD+ GS N L++ RAQ V D L + G+ D I Sbjct: 253 GSVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPADKI 295
>SECBCHAPRONE#Bacterial protein-transport SecB chaperone protein signature. Length = 170 Score = 154 bits (391), Expect = 7e-51 Identities = 50/150 (33%), Positives = 87/150 (58%), Gaps = 3/150 (2%) Query: 2 SDVENQPFFNIQRVYLKDMSLEQPNSPAIFLEQDMPSVEVEVDVKAERLAESVFEVVVSG 61 + QP IQR+Y+KD+S E PN P IF + P + ++ +A+++ + ++EV ++ Sbjct: 12 TQATQQPVLQIQRIYVKDVSFEAPNLPHIFQQDWEPKLSFDLSTEAKQVGDDLYEVCLNI 71 Query: 62 TVTAKVK--DKVAFLIEAKQAGIFDIRNIPDEQLDPLVGIACPTILFPYLRSNIADAITR 119 +V ++ VAF+ E KQAG+F I + + Q+ + CP +LFPY R ++ + R Sbjct: 72 SVETTMESSGDVAFICEVKQAGVFTISGLEEMQMAHCLTSQCPNMLFPYARELVSSLVNR 131 Query: 120 AGFPPIHLAEINFQALYEQRLAQLQQQAGA 149 FP ++L+ +NF AL+ L + Q+QA Sbjct: 132 GTFPALNLSPVNFDALFMDYLQR-QEQAEQ 160
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 26.3 bits (58), Expect = 0.048 Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 4/59 (6%) Query: 79 KIAQVAKNKSTPVLLVCQNG---QQSQKAARE-VQAAGYAEVHVLEGGVAAWQQAGMPV 133 ++ + + +P +LVC Q ++A RE Q AG EV ++E +AA AG+PV Sbjct: 97 QVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPV 155
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 27.9 bits (62), Expect = 0.026 Identities = 11/41 (26%), Positives = 20/41 (48%), Gaps = 2/41 (4%) Query: 92 ADDLLAVLAHMRAQPAHAELPLVLAGFSFGTFVLSHVAKRL 132 D LA++ +A+ ++L G+SFG V+ V + Sbjct: 100 TQDTLAIIDKYQAE--FGTQKVILIGYSFGAEVIPFVLNEM 138
>PF03309#Bvg accessory factor Length = 271 Score = 167 bits (425), Expect = 4e-53 Identities = 58/278 (20%), Positives = 95/278 (34%), Gaps = 40/278 (14%) Query: 6 LLIDAGNSRIKWALADA---RRTLVDTGAFGHTRDGGADPDWSALPRPHGAWISNVAGAD 62 L ID N+ L +V + AD I + G D Sbjct: 3 LAIDVRNTHTVVGLISGSGDHAKVVQQWRIRTEPEVTADE--------LALTIDGLIGDD 54 Query: 63 ---------------VAARLDALLDARWPGLPRTTIRSRPAQCGVTNGYTTPDQLGSDRW 107 V + +L+ WP +P I + G+ P ++G+DR Sbjct: 55 AERLTGASGLSTVPSVLHEVRVMLEQYWPNVPHVLIEPG-VRTGIPLLVDNPKEVGADRI 113 Query: 108 AGLIGARAAFPGEHLLIATFGTATTLEALRADGRFTGGLIAPGWALMMRALGTHTAQLPT 167 + A + +++ FG++ ++ + A G F GG IAPG + A +A L Sbjct: 114 VNCLAAYHKYGTAAIVV-DFGSSICVDVVSAKGEFLGGAIAPGVQVSSDAAAARSAALRR 172 Query: 168 LTTDIASGLLAGAQAEPFQVDTPRSLSAGCLYAQAGLIE----RAWRDLADAWQAPVRLV 223 + ++ +T + AG ++ AGL++ R D+ A V +V Sbjct: 173 VELTRPRSVIGK--------NTVECMQAGAVFGFAGLVDGLVNRIRDDVDGFSGADVAVV 224 Query: 224 LAGGAADDVARALTLPHTRHDALILSGLALIAAEGAAQ 261 G A V L L L GL L+ A Sbjct: 225 ATGHTAPLVLPDLRTVEHYDRHLTLDGLRLVFERNRAN 262
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 32.1 bits (73), Expect = 0.004 Identities = 79/356 (22%), Positives = 115/356 (32%), Gaps = 44/356 (12%) Query: 80 GIAADRFGDRRVLLTGLVATAAMLALMVITIVPSAHAVPPLM--RVVAAMC-CVGLLGGS 136 G +DRFG R VLL L A A+M A + L R+VA + G + G+ Sbjct: 64 GALSDRFGRRPVLLVSLAGAAVDYAIMAT-----APFLWVLYIGRIVAGITGATGAVAGA 118 Query: 137 V--NGSSGRAVMRWFGERERGLAMSIRQTAVPLGGGVGAALLPSLASHAGFAAVYGALML 194 + + G R FG A P+ GG+ P AA L Sbjct: 119 YIADITDGDERARHFG--FMSACFGFGMVAGPVLGGLMGGFSPHAPFF--AAAALNGLNF 174 Query: 195 LCAGSAALTWRWLHEPPHAPATAHGPAAHRPAAQQPPAAATRSPLASGR---VWRIVLGI 251 L L E RP ++ A G + + Sbjct: 175 L------TGCFLLPESH--------KGERRPLRREALNPLASFRWARGMTVVAALMAVFF 220 Query: 252 GALCAPQFAVLTFATVFLHDFG-RLGLAGISAAMVALQVGAMVMRVWSGRHTDRHGNRRA 310 Q + F GIS A + + ++ + +G R G RRA Sbjct: 221 IMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGI-LHSLAQAMITGPVAARLGERRA 279 Query: 311 YLRGSVCVAAGSFALLAAATAGSPHVPLAAIVAILVFAGICVSAWHGVAYTELATLAGAN 370 + G + G + LLA AT G P I+ +L GI + A + L+ Sbjct: 280 LMLGMIADGTG-YILLAFATRGWMAFP---IMVLLASGGIGMPALQAM----LSRQVDEE 331 Query: 371 HAGTALGMANTIVYLGLFATPLAIPPLLAVS--SWS-VVWLAAALIAGATYPLFAR 423 G G + L PL + A S +W+ W+A A + P R Sbjct: 332 RQGQLQGSLAALTSLTSIVGPLLFTAIYAASITTWNGWAWIAGAALYLLCLPALRR 387
>FRAGILYSIN#Fragilysin metallopeptidase (M10C) enterotoxin signature. Length = 405 Score = 30.0 bits (67), Expect = 0.001 Identities = 14/39 (35%), Positives = 22/39 (56%), Gaps = 2/39 (5%) Query: 1 MRRVALVVVLCAATFVAACSDDAPHDAHTADGSPPAGAS 39 M+ V L+++L A +AACS++A + D P AS Sbjct: 9 MKNVKLLLMLGTAALLAACSNEADSLTTSID--APVTAS 45
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 86.8 bits (215), Expect = 2e-21 Identities = 82/353 (23%), Positives = 129/353 (36%), Gaps = 46/353 (13%) Query: 22 VAAAAPVHAQSSVSLYGQVDEWVGATKFPGGDRAWNV-----SGGGMSTSYWGLHGAEDL 76 AA PV A + V+LYG + V ++ + A +G S G G EDL Sbjct: 9 TLAALPVAAMADVTLYGTIKAGVETSRSVAHNGAQAASVETGTGIVDLGSKIGFKGQEDL 68 Query: 77 GNGYKAIFTLESFFRAQNGQFGRFQGDTFFARNAYVGVSSPYGTVTAGRLTTHLFLSTIL 136 GNG KAI+ +E G + R +++G+ +G + GRL Sbjct: 69 GNGLKAIWQVEQKASIAGTDSG------WGNRQSFIGLKGGFGKLRVGRL---------- 112 Query: 137 FNPFYDSYTFSPMVYHVFLGLGTFPTYPSDQGAVGDSGWNNALSYTSPSFGGLNFGAMYA 196 + D+ +P ++ A ++ + Y SP F GL+ YA Sbjct: 113 NSVLKDTGDINPWD-------SKSDYLGVNKIAEPEARLISV-RYDSPEFAGLSGSVQYA 164 Query: 197 LGNTAGDNRSKKWSAQFNYANGPFAATAVYQYVNFNNGPQDLSSLVTGMKSQGIGLVGAT 256 L + AG + S+ + A FNY NG F Y + ++ V K Q LV Sbjct: 165 LNDNAGRHNSESYHAGFNYKNGGFFVQYGGAYKRHHQVQEN----VNIEKYQIHRLVS-G 219 Query: 257 YDLKYVKLFGQYMYTKNDQVAGSWHVNTAQGGVSVPLG--VGNAMASYAY------SRDG 308 YD + + ++ ++ + + +Q V+ L GN +Y S D Sbjct: 220 YDNDALYAS-VAVQQQDAKLVEENYSHNSQTEVAATLAYRFGNVTPRVSYAHGFKGSFDA 278 Query: 309 GGLDQTRQTWAVGYDYPLSKRTDVYAAYM---NDHISGLSSGNTFGAGIRAKF 358 + VG +Y SKRT + G G+R KF Sbjct: 279 TNYNNDYDQVVVGAEYDFSKRTSALVSAGWLQEGKGESKFVSTAGGVGLRHKF 331
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 29.6 bits (66), Expect = 0.015 Identities = 12/96 (12%), Positives = 29/96 (30%), Gaps = 5/96 (5%) Query: 2 GTTIRDVARAAEVSIGTVSRALKNQPGLSEATRARIVE-----IAQRLGYDPAQLRPRIR 56 T++ ++A+AA V+ G + K++ L + P +R Sbjct: 31 STSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPGDPLSVLR 90 Query: 57 RLTFLLHRQHNRFPASPFFSHVLHGVEDACRERGIV 92 + + ++ + E +V Sbjct: 91 EILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVV 126
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 370 bits (951), Expect = e-129 Identities = 164/378 (43%), Positives = 221/378 (58%), Gaps = 21/378 (5%) Query: 21 IAAALVLAACAF---GAPGAHAERLKDLAQIQGVRDNPLIGYGLVVGLDGTGDQTMQTPF 77 IAAALV +A F A R+KD+A +Q RDN LIGYGLVVGL GTGD +PF Sbjct: 7 IAAALVFSALPFLSTPPAQADTSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPF 66 Query: 78 TTQTLANMLANLGISINNGSANGGPSSLNNMQLKNVAAVMVTATLPPFARPGEALDVTVS 137 T Q++ ML NLGI+ G +N KN+AAVMVTA LPPFA PG +DVTVS Sbjct: 67 TEQSMRAMLQNLGITTQGGQSN----------AKNIAAVMVTANLPPFASPGSRVDVTVS 116 Query: 138 SLGNAKSLRGGTLLLTPLKGADGQVYALAQGNMAVGGAGASANGSRVQVNQLAAGRIVGG 197 SLG+A SLRGG L++T L GADGQ+YA+AQG + V G A + + + + R+ G Sbjct: 117 SLGDATSLRGGNLIMTSLSGADGQIYAVAQGALIVNGFSAQGDAATLTQGVTTSARVPNG 176 Query: 198 AIVERSVPNAIAQMNGVLQLQLNDMDYGTAQRIVSAVNS----SFGPGTATALDGRTIQL 253 AI+ER +P+ L LQL + D+ TA R+ VN+ +G A D + I + Sbjct: 177 AIIERELPSKFKDSV-NLVLQLRNPDFSTAVRVADVVNAFARARYGDPIAEPRDSQEIAV 235 Query: 254 AAPADSAQQVAFMARLQNLDVSPDKAAAKVILNARTGSIVMNQMVTLQSCAVAHGNLSVV 313 P + MA ++NL V D AKV++N RTG+IV+ V + AV++G L+V Sbjct: 236 QKPRVA-DLTRLMAEIENLTVETD-TPAKVVINERTGTIVIGADVRISRVAVSYGTLTVQ 293 Query: 314 VNTQPVVSQPGPFSNGQTVVAQQSQIQLKQDNGALKMVTAGANLADVVKALNSLGATPAD 373 V P V QP PFS GQT V Q+ I Q+ + + G +L +V LNS+G Sbjct: 294 VTESPQVIQPAPFSRGQTAVQPQTDIMAMQEGSKVA-IVEGPDLRTLVAGLNSIGLKADG 352 Query: 374 LMSILQAMKAAGALRADL 391 +++ILQ +K+AGAL+A+L Sbjct: 353 IIAILQGIKSAGALQAEL 370
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 216 bits (551), Expect = 3e-73 Identities = 129/222 (58%), Positives = 163/222 (73%), Gaps = 7/222 (3%) Query: 14 AVCALAVAALAGCAQIPRDPIIQQPMTAQPPMPMSMQAPGSIY---NPGYAG-RPLFEDQ 69 A+ +L V +L GCA IP P++Q +AQP + A GSI+ P G +PLFED+ Sbjct: 10 AISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINYGYQPLFEDR 69 Query: 70 RPRNVGDILTIMIAENINATKSSGANTNRQGNTDFSVPTAG-FLGGLF--AKANMSAAGA 126 RPRN+GD LTI++ EN++A+KSS AN +R G T+F T +L GLF A+A++ A+G Sbjct: 70 RPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNARADVEASGG 129 Query: 127 NKFAATGGASAANTFNGTITVTVTNVLPNGNLVVSGEKQMLINQGNEFVRFSGVVNPNTI 186 N F GGA+A+NTF+GT+TVTV VL NGNL V GEKQ+ INQG EF+RFSGVVNP TI Sbjct: 130 NTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRFSGVVNPRTI 189 Query: 187 SGANSVYSTQVADAKIEYSSKGYINEAETMGWLQRFFLNLAP 228 SG+N+V STQVADA+IEY GYINEA+ MGWLQRFFLNL+P Sbjct: 190 SGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSP 231
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 43.8 bits (103), Expect = 4e-07 Identities = 9/42 (21%), Positives = 23/42 (54%) Query: 220 EASNVNVVQELVNMIQTQRAYEINSKAVTTSDQMLQTVTQMK 261 S VN+ +E N+ + Q+ Y N++ + T++ + + ++ Sbjct: 505 SISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR 546 Score = 39.6 bits (92), Expect = 9e-06 Identities = 17/80 (21%), Positives = 33/80 (41%), Gaps = 14/80 (17%) Query: 4 SLYIAATGMNAQQAQMDVISNNLANTSTNGFKASRAVFEDLLYQTIRQPGANSTQQTELP 63 + A +G+NA QA ++ SNN+++ + G+ + + + L Sbjct: 3 LINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIM--------------AQANSTLG 48 Query: 64 SGLQLGTGVQQVATERLYTQ 83 +G +G GV +R Y Sbjct: 49 AGGWVGNGVYVSGVQREYDA 68
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 28.0 bits (62), Expect = 0.039 Identities = 9/34 (26%), Positives = 18/34 (52%) Query: 4 LIYTAMTGASQSLDQQAIVANNLANASTTGFRAQ 37 LI AM+G + + +NN+++ + G+ Q Sbjct: 3 LINNAMSGLNAAQAALNTASNNISSYNVAGYTRQ 36
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 34.9 bits (80), Expect = 5e-04 Identities = 18/58 (31%), Positives = 25/58 (43%) Query: 356 ISAPGSTNHGVLQGSALENSNVDLTSQLVNLITAQRNYQANAQTIKTQQTVDQTLINL 413 SA L S V+L + NL Q+ Y ANAQ ++T + LIN+ Sbjct: 488 SSATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545 Score = 31.5 bits (71), Expect = 0.007 Identities = 19/78 (24%), Positives = 33/78 (42%), Gaps = 11/78 (14%) Query: 6 GLSGLAGASNALDVIGNNIANANTVGFKSSTA----QFSDMYANSIATSVNTQIGIGTGL 61 +SGL A AL+ NNI++ N G+ T S + A +G G + Sbjct: 7 AMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGG-------WVGNGVYV 59 Query: 62 ASVQQQFGQGTINTTNSS 79 + VQ+++ N ++ Sbjct: 60 SGVQREYDAFITNQLRAA 77
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 26.8 bits (59), Expect = 0.032 Identities = 10/38 (26%), Positives = 17/38 (44%) Query: 102 NVDPVQEMVNMISASRSYQANVETLNTAKTLMLKTLTI 139 V+ +E N+ + Y AN + L TA + + I Sbjct: 508 GVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 88.3 bits (219), Expect = 1e-22 Identities = 34/114 (29%), Positives = 55/114 (48%), Gaps = 2/114 (1%) Query: 5 ILLVDDHAIVRQGVRHLLIDRGVAREVTEAETGSDAVAAVDRQTFDVILLDISLPDTNGI 64 IL+ DD A +R + L G +V + + D+++ D+ +PD N Sbjct: 6 ILVADDDAAIRTVLNQALSRAGY--DVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 65 ELLKRIKRKLPGTPVLMFSMYREDQYAVRALKAGASGYLSKTVNAAQMIGAIQQ 118 +LL RIK+ P PVL+ S A++A + GA YL K + ++IG I + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 60.2 bits (146), Expect = 4e-14 Identities = 17/79 (21%), Positives = 32/79 (40%), Gaps = 2/79 (2%) Query: 9 AAALVYDPKGGDAAPRVVAKGYGLLAEMIVARARDAGLYVHTAPEMV-SLLMQVDLDDRI 67 A ++Y G P V K + + A + G+ + + +L +D I Sbjct: 268 AIGILYKR-GETPLPLVTFKYTDAQVQTVRKIAEEEGVPILQRIPLARALYWDALVDHYI 326 Query: 68 PPQLYQAVADLLAWLYALD 86 P + +A A++L WL + Sbjct: 327 PAEQIEATAEVLRWLERQN 345
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 65.1 bits (158), Expect = 3e-17 Identities = 46/112 (41%), Positives = 66/112 (58%), Gaps = 9/112 (8%) Query: 8 ANVSGIGSVLQQMQAMAAQAGGGVASPTAALAGSGAATAGTFASAMKASLDKISGDQQHA 67 + + GI V+ Q+QA A A + P + +FA + A+LD+IS Q A Sbjct: 1 SAIQGIEGVISQLQATAMSARAQESLPQPTI---------SFAGQLHAALDRISDTQTAA 51 Query: 68 LGEAQAFEVGAANVSLNDVMVDMQKANIGFQFGLQVRNKLVSAYNDIMQMSV 119 +A+ F +G V+LNDVM DMQKA++ Q G+QVRNKLV+AY ++M M V Sbjct: 52 RTQAEKFTLGEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV 103
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 475 bits (1225), Expect = e-165 Identities = 251/550 (45%), Positives = 362/550 (65%), Gaps = 23/550 (4%) Query: 52 ISRMKGNPKLPFVIAVAFAIAAITALVLWSRAPDYRVLYSNLSDRDGGAIIAALQQANVP 111 ++R++ NP++P ++A + A+A + A+VLW++ PDYR L+SNLSD+DGGAI+A L Q N+P Sbjct: 16 LNRLRANPRIPLIVAGSAAVAIVVAMVLWAKTPDYRTLFSNLSDQDGGAIVAQLTQMNIP 75 Query: 112 YKFADAGGAILVPSNQVHETRLKLAALGLPKGGSVGFELMDNQKFGISQFAEQVNYQRAL 171 Y+FA+ GAI VP+++VHE RL+LA GLPKGG+VGFEL+D +KFGISQF+EQVNYQRAL Sbjct: 76 YRFANGSGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQFSEQVNYQRAL 135 Query: 172 EGELQRTIESINAVRGARVHLAIPKPSVFVRDKEAPSASVFVDLYPGRVLDEGQVQAITR 231 EGEL RTIE++ V+ ARVHLA+PKPS+FVR++++PSASV V L PGR LDEGQ+ A+ Sbjct: 136 EGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLEPGRALDEGQISAVVH 195 Query: 232 MVSSGVPDMPAKNVTIVDQDGNLLTQTASASG-LDASQLKYVQQVEHNTQKRIDAILAPI 290 +VSS V +P NVT+VDQ G+LLTQ+ ++ L+ +QLK+ VE Q+RI+AIL+PI Sbjct: 196 LVSSAVAGLPPGNVTLVDQSGHLLTQSNTSGRDLNDAQLKFANDVESRIQRRIEAILSPI 255 Query: 291 FGTGNARSQVSADIDFSKLEQTSESYGPNGTPQQAAIRSQQTSSATELAQGGASGVPGAL 350 G GN +QV+A +DF+ EQT E Y PNG +A +RS+Q + + ++ G GVPGAL Sbjct: 256 VGNGNVHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQVGAGYPGGVPGAL 315 Query: 351 SNTPPQPASAPIVA-----GNGQN---------GAQSTPVSDRKDQTTNYELDKTIRHVE 396 SN P P API N QN + P S ++++T+NYE+D+TIRH + Sbjct: 316 SNQPAPPNEAPIATPPTNQQNAQNTPQTSTSTNSNSAGPRSTQRNETSNYEVDRTIRHTK 375 Query: 397 QPMGNVKRLSVAVVVNYQPVADAKGHVTMQPLPPPKLAQVEQLVKDAMGYDEKRGDSVNV 456 +G+++RLSVAVVVNY+ +AD K PL ++ Q+E L ++AMG+ +KRGD++NV Sbjct: 376 MNVGDIERLSVAVVVNYKTLADGKP----LPLTADQMKQIEDLTREAMGFSDKRGDTLNV 431 Query: 457 VNSAFSSVGDPYADLPWWRQPDMIAMAKEAAKWLGIAAAAAALYFMFVRPAMRRAFPPPE 516 VNS FS+V + +LP+W+Q I A +WL + A L+ VRP + R + Sbjct: 432 VNSPFSAVDNTGGELPFWQQQSFIDQLLAAGRWLLVLVVAWILWRKAVRPQLTRRVEEAK 491 Query: 517 PVAPALAAPDDPVALDGLPAPDKADEPDPLLLGFENEKNRYERNLDYARTIARQDPKIVA 576 + + + DE L N++ E R ++ DP++VA Sbjct: 492 AAQEQAQVRQE--TEEAVEVRLSKDE--QLQQRRANQRLGAEVMSQRIREMSDNDPRVVA 547 Query: 577 TVVKNWVSDE 586 V++ W+S++ Sbjct: 548 LVIRQWMSND 557
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 297 bits (763), Expect = e-102 Identities = 113/324 (34%), Positives = 188/324 (58%) Query: 5 GLTKSALLLMSIGEEEAAEVFKFLAPREVQKIGAAMAALKNVTREQVEGVLQEFAKEAEQ 64 G K+A+LL+SIG E +++VFK+L+ E++ + +A L+ +T E + VL EF + Sbjct: 17 GKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKLETITSELKDNVLLEFKELMMA 76 Query: 65 HTALSLDSSEYIRSVLTKALGEDKAGVLIDRILQGSDTSGIEGLKWMDSGAVAELIKNEH 124 + +Y R +L K+LG KA +I+ + + E ++ D + I+ EH Sbjct: 77 QEFIQKGGIDYARELLEKSLGTQKAVDIINNLGSALQSRPFEFVRRADPANILNFIQQEH 136 Query: 125 PQIIATILVHLDRDQASEIASCFTERLRNDVLLRIATLDGIQPAALRELDDVLTGLLSGS 184 PQ IA IL +LD +AS I S ++ +V RIA +D P +RE++ VL L+ Sbjct: 137 PQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVVREVERVLEKKLASL 196 Query: 185 DNLKRSPMGGIRTAAEILNFMTSNHEEGVLESVRQYDADLAQKIVDQMFVFENLLDLEDR 244 + + GG+ EI+N E+ ++ES+ + D +LA++I +MFVFE+++ L+DR Sbjct: 197 SSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPELAEEIKKKMFVFEDIVLLDDR 256 Query: 245 AIQMVLKEVESETLIIALKGAPPALRQKFLANMSQRAAELLAEDLDARGPVRVSEVETQQ 304 +IQ VL+E++ + L ALK +++K NMS+RAA +L ED++ GP R +VE Q Sbjct: 257 SIQRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRAASMLKEDMEFLGPTRRKDVEESQ 316 Query: 305 RRILQIVRNLAESGQIVIGGKAED 328 ++I+ ++R L E G+IVI E+ Sbjct: 317 QKIVSLIRKLEEQGEIVISRGGEE 340
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 113 bits (284), Expect = 4e-33 Identities = 71/213 (33%), Positives = 115/213 (53%), Gaps = 10/213 (4%) Query: 15 YQRWEMASFDPPPPPPPPDDA------AAAAAALAEELQRVRDAAHAEGHAAGHVEGQAL 68 ++ W PP P A +L ++L +++ AH +G+ AG EG+ Sbjct: 7 WKTWTPDDLAPPQAEFVPIVEPEETIIEEAEPSLEQQLAQLQMQAHEQGYQAGIAEGRQQ 66 Query: 69 GYQAGFDQGREQGFEAGQAEAREQAAQLAA----LAASFREAVSSVEHDLASDLAQLALD 124 G++ G+ +G QG E G AEA+ Q A + A L + F+ + +++ +AS L Q+AL+ Sbjct: 67 GHKQGYQEGLAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRLMQMALE 126 Query: 125 IAQQVVRQHVKHDPAALVAAVRDVLAAEPALSGAPHLAVNPADLPVVEAYLQDDLDTLGW 184 A+QV+ Q D +AL+ ++ +L EP SG P L V+P DL V+ L L GW Sbjct: 127 AARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGATLSLHGW 186 Query: 185 TVRTDTSIERGGCRAHAATGEVDATLPTRWQRV 217 +R D ++ GGC+ A G++DA++ TRWQ + Sbjct: 187 RLRGDPTLHPGGCKVSADEGDLDASVATRWQEL 219
>FLGFLIJ#Flagellar FliJ protein signature. Length = 147 Score = 63.3 bits (153), Expect = 1e-15 Identities = 44/140 (31%), Positives = 73/140 (52%) Query: 1 MAHGFPLQLLLDRAQEDLDTATKQLGTAQRDRTAAAEQLDALLRYRDEYHARFSQSAQHG 60 MA L L D A+++++ A + LG +R A EQL L+ Y++EY + G Sbjct: 1 MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAG 60 Query: 61 MPAGNWRNFQAFIDTLDAAIAQQRNVLAAAELRIDEARPNWQQKKRTVGSYETLQARGVA 120 + + W N+Q FI TL+ AI Q R L ++D A +W++KK+ + +++TLQ R Sbjct: 61 ITSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQST 120 Query: 121 QETQRAAKREQRDADEHAAK 140 + +Q+ DE A + Sbjct: 121 AALLAENRLDQKKMDEFAQR 140
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 66.0 bits (160), Expect = 7e-14 Identities = 71/210 (33%), Positives = 94/210 (44%), Gaps = 3/210 (1%) Query: 202 TAPASTTSASAAAAPLTPKVPTFERTLADAKGALATQPTPTQATAQALQAGATGQPAAHA 261 TA S A TPKV T+ + ++ A A G PA Sbjct: 128 TASLSALFAMLPGFDNTPKVTDAPSTVLPTEKPTLFTKLTSEQLTTAQPDDAPGTPAQPL 187 Query: 262 LAATEEAASPAADASVAAAATAAAAAQANLQASPAASSLAAANAHALAPHVGTADWTDAL 321 EA S A S + TAAA+ L L A L+ +G+ +W +L Sbjct: 188 TPLVAEAQSKAEVISTPSPVTAAASP---LITPHQTQPLPTVAAPVLSAPLGSHEWQQSL 244 Query: 322 SQKVVFLSNAHQQSAELTLNPPDLGPLQVVLRVADNHAHALFVSQHAQVRDAVEAALPKL 381 SQ + + QQSAEL L+P DLG +Q+ L+V DN A VS H VR A+EAALP L Sbjct: 245 SQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMVSPHQHVRAALEAALPVL 304 Query: 382 REAMEAGGLGLGSATVSDGGFAQQQQNPQQ 411 R + G+ LG + +S F+ QQQ Q Sbjct: 305 RTQLAESGIQLGQSNISGESFSGQQQAASQ 334
>SURFACELAYER#Lactobacillus surface layer protein signature. Length = 439 Score = 29.3 bits (65), Expect = 0.021 Identities = 35/129 (27%), Positives = 43/129 (33%), Gaps = 9/129 (6%) Query: 1 MKKT-RVILAAACLLPASPALLAACRPI----TQEESERWAETRPMPNQILTTFNISFPA 55 MKK R++ AAA L A + A P+ T + T +IS A Sbjct: 1 MKKNLRIVSAAAAALLAVAPIAATAMPVNAATTINADSAINANTNAKYDVDVTPSISAIA 60 Query: 56 GVVDIDPDLPIGSPLVSGESAPTPAMSFIACDPPTG---TINVDFMTPPKLSSL-GGKIY 111 V D I L SA S+ A P TI K + L K Y Sbjct: 61 AVAKSDTMPAIPGSLTGSISASYNGKSYTANLPKDSGNATITDSNNNTVKPAELEADKAY 120 Query: 112 DTNVPGVGF 120 VP V F Sbjct: 121 TVTVPDVSF 129
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 57.0 bits (137), Expect = 4e-10 Identities = 51/260 (19%), Positives = 77/260 (29%), Gaps = 9/260 (3%) Query: 779 PPPSETPPPSEMPPPSEMPPPSEMPPPSEMPPPSEMPPPSEMPPPSETPPPSETPPP-SE 837 TP + PS E+ E P +PPP+ P T +E S+ Sbjct: 994 TTNITTPNNIQADVPSVPSNNEEIARVDEAP----VPPPAPATPSETTETVAENSKQESK 1049 Query: 838 TPPPSETPPPSETPPPSETPPPSETPPPSETPPPSETPPPSETPPPSETPPPSETPPPSE 897 T +E T E +++ + T SET T E Sbjct: 1050 TVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKE 1109 Query: 898 TPPPSETPPPSETPP-PSETPPPSETPPPSETPPPSETPPPSETPPPSETPPPSETPPPS 956 ET E P S+ P E ET P P P + P S+T + Sbjct: 1110 EKAKVETEKTQEVPKVTSQVSPKQEQS---ETVQPQAEPARENDPTVNIKEPQSQTNTTA 1166 Query: 957 ETPPPSETPPPSETPPPSETPPPSETPPPSETPPPSETPPPSETPPPSETPPPSETPPPS 1016 +T P++ + P +E+ + E P + T + P S Sbjct: 1167 DTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRS 1226 Query: 1017 ETPPPSETPPPSETPPPSET 1036 P P + + T Sbjct: 1227 VRSVPHNVEPATTSSNDRST 1246 Score = 53.9 bits (129), Expect = 3e-09 Identities = 49/259 (18%), Positives = 74/259 (28%), Gaps = 9/259 (3%) Query: 791 PPPSEMPPPSEMPPPSEMPPPSEMPPPSEMPPPSETPPPSETPPPSETPPPSETPPP-SE 849 P + PS E+ E P PPP+ P T +E S+ Sbjct: 994 TTNITTPNNIQADVPSVPSNNEEIARVDEAP----VPPPAPATPSETTETVAENSKQESK 1049 Query: 850 TPPPSETPPPSETPPPSETPPPSETPPPSETPPPSETPPPSETPPPSETPPPSETPPPSE 909 T +E T E +++ + T SET T E Sbjct: 1050 TVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKE 1109 Query: 910 TPPPSETPPPSETPP-PSETPPPSETPPPSETPPPSETPPPSETPPPSETPPPSETPPPS 968 ET E P S+ P E ET P P P + P S+T + Sbjct: 1110 EKAKVETEKTQEVPKVTSQVSPKQEQS---ETVQPQAEPARENDPTVNIKEPQSQTNTTA 1166 Query: 969 ETPPPSETPPPSETPPPSETPPPSETPPPSETPPPSETPPPSETPPPSETPPPSETPPPS 1028 +T P++ + P +E+ + E P + T + P S Sbjct: 1167 DTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRS 1226 Query: 1029 ETPPPSETPPPSEEPPESE 1047 P P + + Sbjct: 1227 VRSVPHNVEPATTSSNDRS 1245 Score = 49.7 bits (118), Expect = 7e-08 Identities = 45/261 (17%), Positives = 71/261 (27%), Gaps = 9/261 (3%) Query: 724 PPPSVEPPPPSEMPPPSEMPPPSEMPPPSEMPPPSEMPPPSEMPPPSEMPPPSEMPPPSE 783 ++ P + PS E+ E P +PPP+ P +E Sbjct: 993 DTTNITTPNNIQADVPSVPSNNEEIARVDEAP----VPPPAPATPSETTETVAENSKQES 1048 Query: 784 TPPPSEMPPPSEMPPPSEMPPPSEMPPPSEMPPPSEMPP-PSETPPPSETPPPSETPPPS 842 +E + +E+ SET T Sbjct: 1049 KTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEK 1108 Query: 843 ETPPPSETPPPSETPP-PSETPPPSETPPPSETPPPSETPPPSETPPPSETPPPSETPPP 901 E ET E P S+ P E ET P P P + P S+T Sbjct: 1109 EEKAKVETEKTQEVPKVTSQVSPKQEQS---ETVQPQAEPARENDPTVNIKEPQSQTNTT 1165 Query: 902 SETPPPSETPPPSETPPPSETPPPSETPPPSETPPPSETPPPSETPPPSETPPPSETPPP 961 ++T P++ + P +E+ + E P + T + P Sbjct: 1166 ADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRR 1225 Query: 962 SETPPPSETPPPSETPPPSET 982 S P P + + T Sbjct: 1226 SVRSVPHNVEPATTSSNDRST 1246 Score = 49.7 bits (118), Expect = 7e-08 Identities = 49/271 (18%), Positives = 73/271 (26%), Gaps = 9/271 (3%) Query: 726 PSVEPPPPSEMPPPSEMPPPSEMPPPSEMPPPSEMPPPSEMPPPSEMPPPSEMPPPSETP 785 P VE + P + PS E+ E P +PPP+ P T Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAP----VPPPAPATPSETTE 1038 Query: 786 PPSEMPPPSEMPPPSEMPPPSEMPPPSEMPPPSEMPPPSETPPPSE-TPPPSETPPPSET 844 +E +E + +E SET T Sbjct: 1039 TVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTT 1098 Query: 845 PPPSETPPPSETPPPSETPPPSETPP-PSETPPPSETPPPSETPPPSETPPPSETPPPSE 903 E ET E P S+ P E ET P P P + Sbjct: 1099 ETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQS---ETVQPQAEPARENDPTVNI 1155 Query: 904 TPPPSETPPPSETPPPSETPPPSETPPPSETPPPSETPPPSETPPPSETPPPSETPPPSE 963 P S+T ++T P++ + P +E+ + E P + T Sbjct: 1156 KEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSES 1215 Query: 964 TPPPSETPPPSETPPPSETPPPSETPPPSET 994 + P S P P + + T Sbjct: 1216 SNKPKNRHRRSVRSVPHNVEPATTSSNDRST 1246
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 83.8 bits (207), Expect = 6e-20 Identities = 42/124 (33%), Positives = 65/124 (52%), Gaps = 16/124 (12%) Query: 321 VVFRGDSMFASGKRVVLPEIEPILNKVASEVARVG---GNVLVSGHTDNQPIRSAAFADN 377 + D +F K + PE + L+++ S+++ + G+V+V G+TD I S A+ N Sbjct: 215 FTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDR--IGSDAY--N 270 Query: 378 QVLSEKRAEFVAQILQRDGTPAERIRAVGKGDTQPVGDNATAAGR---------ALNRRV 428 Q LSE+RA+ V L G PA++I A G G++ PV N + A +RRV Sbjct: 271 QGLSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRV 330 Query: 429 EIMV 432 EI V Sbjct: 331 EIEV 334
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 75.7 bits (186), Expect = 5e-17 Identities = 33/122 (27%), Positives = 59/122 (48%), Gaps = 11/122 (9%) Query: 437 TVQIDSLSLFASGKATFSPAHERRELAHVLRLIRENP-DQRVLIEGHADSEGSADANLRL 495 + S LF KAT P + +L +P D V++ G+ D GS N L Sbjct: 214 HFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGL 273 Query: 496 SEARARAIRDWLVAEGGLSVARFAIQGMGDIRPIADNRSEAGR---------ALNRRVDV 546 SE RA+++ D+L+++ G+ + + +GMG+ P+ N + + A +RRV++ Sbjct: 274 SERRAQSVVDYLISK-GIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEI 332 Query: 547 SL 548 + Sbjct: 333 EV 334
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 849 bits (2196), Expect = 0.0 Identities = 288/865 (33%), Positives = 421/865 (48%), Gaps = 46/865 (5%) Query: 85 PVMQVAARAPTEPAAVAFNPRLFAGGG---VDLSRFAKGNPVEPGSYAVDVTVNGKGRGR 141 AA+AP A + FNPR A DLSRF G + PG+Y VD+ +N Sbjct: 32 VACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGYMAT 91 Query: 142 RDVPFLAVPGSDVAMPCFTLATLEELGVDGDKLVRQLRRSKQDDDAGAPAAHELAPDACL 201 RDV F +PC T A L +G++ + + LA DAC+ Sbjct: 92 RDVTFNTGDSEQGIVPCLTRAQLASMGLNTASV---------------SGMNLLADDACV 136 Query: 202 ALRDTIPDATYSFDSADLTLDVTIPQTVMSKRAYGYVDPSRWDEGINVGLLQYNVNGYTS 261 L I DAT D L++TIPQ MS RA GY+ P WD GIN GLL YN +G + Sbjct: 137 PLTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSV 196 Query: 262 ESNFFGHNFSSLYTGLQSGVNIGPWRFRHRSTLNW----ASRSAGVSWRSLETFVQRDIT 317 ++ G N Y LQSG+NIG WR R +T ++ +S + W+ + T+++RDI Sbjct: 197 QNRI-GGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDII 255 Query: 318 ALRSQIVLGDSFTSGDVFDSFGVRGVQLSSDDRMLPNSLQAYAPTIRGVADTNARVVVRQ 377 LRS++ LGD +T GD+FD RG QL+SDD MLP+S + +AP I G+A A+V ++Q Sbjct: 256 PLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQ 315 Query: 378 GANTVYEETVSPGPFEFNDLPATGYGGDLDVTVTESDGRVRRFSVPFAAVPQLLRPGRHR 437 +Y TV PGPF ND+ A G GDL VT+ E+DG + F+VP+++VP L R G R Sbjct: 316 NGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTR 375 Query: 438 FNVTVGQYR-DNAVDVKPWVAQLVYQRGITNLVTAYAGALSSTGYGSGVLGVALNT-SVG 495 +++T G+YR NA KP Q G+ T Y G + Y + G+ N ++G Sbjct: 376 YSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALG 435 Query: 496 AFAFDVTSAHTSVPGRRTYHGLSSRITYSKMLEPTGTNFSVAAYRYSTSNFFSLQDAVNA 555 A + D+T A++++P + G S R Y+K L +GTN + YRYSTS +F+ D + Sbjct: 436 ALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYS 495 Query: 556 RRDWSGSIGQ---------------YNYRARTRLQLNVNQRLGDRSALYVTGSSQDYWGG 600 R + Q Y R +LQL V Q+LG S LY++GS Q YWG Sbjct: 496 RMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGT 555 Query: 601 QRGRDLQYQVGFNSTFRRMSYSVYAQRARN-GDDRTVTQVGINLTIPLGKQTY---TKSP 656 D Q+Q G N+ F +++++ +N + +N+ IP Sbjct: 556 -SNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQW 614 Query: 657 VFNSLTTSASRDSSGNSAIQMDMSGSKGTIAPFNYGVTASRIAGGDTSALSSFGGYGTYR 716 S + S S D +G + G+ +Y V GGD ++ S+ YR Sbjct: 615 RHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYR 674 Query: 717 SSVGTYSANASLSNKMRQASLGANGAMIIHRGGVTLSPPLGPAAALIEAKGATGGQIVNG 776 G + S S+ ++Q G +G ++ H GVTL PL L++A GA ++ N Sbjct: 675 GGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQ 734 Query: 777 QGASIDRFGYAVIPSLTPYRVNTVEIDPSRLPDDVELGNTSEEVVPRYNSVVFVKMSTVR 836 G D GYAV+P T YR N V +D + L D+V+L N VVP ++V + Sbjct: 735 TGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARV 794 Query: 837 GRPVFATMERQDGSPLPMGTQLFDAAGKSVGGVGQGGMAFLRGLEGSGELTAKWGIGPAD 896 G + T+ + PLP G + + +S G V G +L G+ +G++ KWG Sbjct: 795 GIKLLMTL-THNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENA 853 Query: 897 RCSLPYAVPAASANAGKIKMATRVR 921 C Y +P S +++ R Sbjct: 854 HCVANYQLPPESQQQLLTQLSAECR 878
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 59.0 bits (143), Expect = 8e-12 Identities = 52/249 (20%), Positives = 92/249 (36%), Gaps = 36/249 (14%) Query: 34 LKRKTLALSIAAAGLCAGTQAHAQSSVQLYGLMDLSFPTYRTHADANGKHVIGMGNEGEP 93 +K+ +AL++AA A + V LYG + T R+ A NG + Sbjct: 1 MKKSLIALTLAA------LPVAAMADVTLYGTIKAGVETSRSVAH-NGAQAASVETGTGI 53 Query: 94 WFSGSRWGLRGAEDIGGGTKIIFRLESEFVVANGQMEDEGQIFDRDAWVGVEDERFGKLT 153 GS+ G +G ED+G G K I+++E + +A + +R +++G++ FGKL Sbjct: 54 VDLGSKIGFKGQEDLGNGLKAIWQVEQKASIAGT----DSGWGNRQSFIGLKGG-FGKLR 108 Query: 154 AGFQNTIARDAAAIYGDAYGSAKLTTEEGGWTNSNNFKQMIFYAAGPTGTRYNNGLAWKK 213 G N++ +D I + + S RY++ Sbjct: 109 VGRLNSVLKDTGDI--NPWDSKSDYLGVNKIAEPEAR---------LISVRYDS-----P 152 Query: 214 LFSNGIFASAGYQFSNSTAFATGSAYQVALGYNGGPFAVSGFYNHVNH-------GGFRN 266 F+ G+ S Y +++ +Y Y G F V + H + Sbjct: 153 EFA-GLSGSVQYALNDNAGRHNSESYHAGFNYKNGGFFVQYGGAYKRHHQVQENVNIEKY 211 Query: 267 QTFSVGGNY 275 Q + Y Sbjct: 212 QIHRLVSGY 220
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 95.3 bits (237), Expect = 6e-25 Identities = 28/126 (22%), Positives = 59/126 (46%), Gaps = 1/126 (0%) Query: 2 KLLLVEDNAELAHWIVNLLRGEDFAVDCVGDGERADTVLKTERYDAVLLDMRLPGISGKE 61 +L+ +D+A + + L + V + + D V+ D+ +P + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VLARLRRRNDNVPVLMLTAHGSVDDKVDCFGAGADDYVVKPFESRELVARI-RALIRRQA 120 +L R+++ ++PVL+++A + + GA DY+ KPF+ EL+ I RAL + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 121 GVATTQ 126 + + Sbjct: 125 RPSKLE 130
>PF06580#Sensor histidine kinase Length = 349 Score = 54.9 bits (132), Expect = 2e-10 Identities = 24/128 (18%), Positives = 45/128 (35%), Gaps = 26/128 (20%) Query: 338 LGERLDV--AGSDSLLTALV-----MNLVDNAVRY----TQPGGCVTVVARRDGDAVVLD 386 +RL + +++ V LV+N +++ GG + + +D V L+ Sbjct: 236 FEDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLE 295 Query: 387 VVDNGPGIPAEARPHVFKRFYRVAADTEGSGLGLAIVRE-IAQAHGGSATLAPGPGNRGI 445 V + G + E +G GL VRE + +G A + + Sbjct: 296 VENTGSLALKNTK--------------ESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKV 341 Query: 446 VVTVRLPA 453 V +P Sbjct: 342 NAMVLIPG 349
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 46.5 bits (110), Expect = 6e-09 Identities = 18/84 (21%), Positives = 30/84 (35%), Gaps = 10/84 (11%) Query: 34 RVRGFTLLEMLVVLVIAGLLVSLASLSLTRNPRTDLREEAQRIALLFETAGDEAQVRARP 93 R RGFTLLEM+++L++ G+ + L+ + + R + Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQTLARFEAQLRFVQQRGLQTGQF 61 Query: 94 IAWQPTAHGFRFDVSSPDGWRTLR 117 G PD W+ L Sbjct: 62 F-------GVSVH---PDRWQFLV 75
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 188 bits (478), Expect = 1e-64 Identities = 66/139 (47%), Positives = 92/139 (66%), Gaps = 3/139 (2%) Query: 11 AVRRQRGFTLIEIMVVVAILGILAALIVPKIMSRPDEARRIAAKQDIGTIMQALKLYRLD 70 A +QRGFTL+EIMVV+ I+G+LA+L+VP +M ++A + A DI + AL +Y+LD Sbjct: 3 ATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLD 62 Query: 71 NGRYPTQEQGLNALIQKPSTDPIPNNWKDGGYLERLPNDPWGNGYKYLNPGVHGEIDVFS 130 N YPT QGL +L++ P+ P+ N+ GY++RLP DPWGN Y +NPG HG D+ S Sbjct: 63 NHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDLLS 122 Query: 131 YGADGKEGGESNDSDIGSW 149 G DG+ G E DI +W Sbjct: 123 AGPDGEMGTE---DDITNW 138
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 380 bits (977), Expect = e-132 Identities = 166/406 (40%), Positives = 262/406 (64%), Gaps = 2/406 (0%) Query: 1 MPAFRFEAIDSAGRPQKGVIDADSARGARGQLRTQGLTPLVVEPAASATRGARSQRLAFG 60 M + ++A+D+ G+ +G +ADSAR AR LR +GL PL V+ + + S L+ Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 61 R--KLSQREQAILTRQLASLLIAGLPLDEALGVLTEQAERDYIRELMAAIRAEVLGGHSL 118 R +LS + A+LTRQLA+L+ A +PL+EAL + +Q+E+ ++ +LMAA+R++V+ GHSL Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 119 ANALGQHPRDFPEIYRALVAAGEHTGKLGIVLSRLADYIEQSNALKQKILLAFTYPGIVT 178 A+A+ P F +Y A+VAAGE +G L VL+RLADY EQ ++ +I A YP ++T Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 179 LIAFGIVTFLLSYVVPQVVNVFASTKQQLPVLTVVMMALSEFVRHWWWAILITVALVVWF 238 ++A +V+ LLS VVP+VV F KQ LP+ T V+M +S+ VR + +L+ + Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMA 240 Query: 239 VKATLSRDGPRLAFDRWVLTAPLAGKLVRGYNTVRFASTLGILTAAGVPILRALQAAGET 298 + L ++ R++F R +L PL G++ RG NT R+A TL IL A+ VP+L+A++ +G+ Sbjct: 241 FRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 299 LSNRAMRANIDDAIVRVREGSALSRALNNVKTFPPVLVHLIRSGEATGDVTTMLDRAAEG 358 +SN R + A VREG +L +AL FPP++ H+I SGE +G++ +ML+RAA+ Sbjct: 301 MSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADN 360 Query: 359 EARELERRTMFLTSLLEPLLILAMGGIVLVIVLAVMLPIIELNNMV 404 + RE + L EPLL+++M +VL IVLA++ PI++LN ++ Sbjct: 361 QDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 394 bits (1014), Expect = e-129 Identities = 202/692 (29%), Positives = 325/692 (46%), Gaps = 87/692 (12%) Query: 6 TTLIVAGIIVSQAAYAQVTLNFVNADIDQVAKAIGAATGKTIIVDPRVKGQLNLVSERSV 65 T LI A ++ AA + + +F DI + + KT+I+DP V+G + + S + Sbjct: 13 TLLIFAALLFRPAAAEEFSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRSYDML 72 Query: 66 PEDQALKTLQSALRMQGFALV-QDHGVLKVVPEADAKLQGVPTYIGNAPRARGDQVITQV 124 E+Q + S L + GFA++ ++GVLKVV DAK VP +A GD+V+T+V Sbjct: 73 NEEQYYQFFLSVLDVYGFAVINMNNGVLKVVRSKDAKTAAVPV-ASDAAPGIGDEVVTRV 131 Query: 125 FELHNESANNLLPVLRPLI--SPNNTVTAYPANNTIVVTDYADNVRRIAQIIAGVDSAAG 182 L N +A +L P+LR L + +V Y +N +++T A ++R+ I+ VD+A Sbjct: 132 VPLTNVAARDLAPLLRQLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDNAGD 191 Query: 183 AQVQVIPLRNANAIDLAAQLQKMLDPGAIGNSDATLKVSVTADPRTNSLMLRASSASRLA 242 V +PL A+A D+ + ++ + ++ +V AD RTN++++ SR Sbjct: 192 RSVVTVPLSWASAADVVKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSGEPNSR-Q 250 Query: 243 AAKRIVQQLDAPSGVPGNMHVVPLRNADAVKLAKTLRGMLGKGGNDSGSSASSNDANSFN 302 +++QLD GN V+ L+ A A L + Sbjct: 251 RIIAMIKQLDRQQATQGNTKVIYLKYAKASDLVEV------------------------- 285 Query: 303 QSGGSSASGNFSTGTSGTPPLPSGGLGGGSSSSSAYGSGASGSGGVGSGGLLGGDKDKSD 362 L G SS+ + A + Sbjct: 286 -------------------------LTGISSTMQSEKQAAKPVAALDKNI---------- 310 Query: 363 ENQPGGMIQADAATNSLIITASDPVYRNLRSVIDQLDARRAQVYIEALIVELNSTTQGNL 422 +I+A TN+LI+TA+ V +L VI QLD RR QV +EA+I E+ NL Sbjct: 311 ------IIKAHGQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNL 364 Query: 423 GIQWQVASGQFLGGTNLAPTAGTGLGNSIVNLTSGG-TAATTGLAANLAGLSQGLNIGWL 481 GIQW + TN T + + G +++ ++ G++ G Sbjct: 365 GIQWANKNAGMTQFTNSGLPISTAIAGANQYNKDGTVSSSLASALSSFNGIAAG------ 418 Query: 482 HNMFGVQGLGALLQYFAGVSDANVLSTPNLITLDNEEAKIVVGQNVPIATGSYSNLTSGT 541 F LL + + ++L+TP+++TLDN EA VGQ VP+ TGS + + Sbjct: 419 ---FYQGNWAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVPVLTGS----QTTS 471 Query: 542 TSNAFNTYDRRDVGLTLHVKPQITDGGILKLQLYTEDSAV--VSGTTNAQTGPTFTKRSI 599 N FNT +R+ VG+ L VKPQI +G + L++ E S+V + +T++ G TF R++ Sbjct: 472 GDNIFNTVERKTVGIKLKVKPQINEGDSVLLEIEQEVSSVADAASSTSSDLGATFNTRTV 531 Query: 600 QSTILADNGEIIVLGGLMQDNYQVSNSKVPLLGDIPWIGQLFRSESKQRQKTNLMVFLRP 659 + +L +GE +V+GGL+ + + KVPLLGDIP IG LFRS SK+ K NLM+F+RP Sbjct: 532 NNAVLVGSGETVVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRNLMLFIRP 591 Query: 660 VIISDRSTAQEVTANRYDYIQGVTGAYKSDNN 691 +I DR ++ ++ +Y + N Sbjct: 592 TVIRDRDEYRQASSGQYTAFNDAQSKQRGKEN 623
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 108 bits (271), Expect = 1e-34 Identities = 45/88 (51%), Positives = 58/88 (65%) Query: 2 NKQELIDAVAAQTGASKAQTGETLDTLLEVIKKAVSKGDAVQLIGFGSFGSGKRAARTGR 61 NKQ+LI VA T +K + +D + + ++KG+ VQLIGFG+F +RAAR GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 62 NPKTGETIKIPAAKTVKFTAGKAFKDAV 89 NP+TGE IKI A+K F AGKA KDAV Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAV 90
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 67.0 bits (163), Expect = 9e-16 Identities = 30/142 (21%), Positives = 51/142 (35%), Gaps = 2/142 (1%) Query: 26 RPRQSRAQATSDALLQAFVQLLLERGYAKATIREIAAVAGVSIGTFYEYFGDKQSLAALC 85 R + AQ T +L ++L ++G + ++ EIA AGV+ G Y +F DK L + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 86 IHRHVQALADRLRDAAHGLAGVPRAELAAALVDVQVDAI--GADAALWSAFFALERQVSP 143 + + + G P + L L+ V + L F V Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 144 LAAYRRHYDAYVALWRDAFAQA 165 +A ++ D Q Sbjct: 123 MAVVQQAQRNLCLESYDRIEQT 144
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.7 bits (72), Expect = 0.002 Identities = 12/70 (17%), Positives = 27/70 (38%) Query: 117 DAEDARHQLERRIAALEAERERLESLRNAAQNDQVPRLFLLQNEHALVLLNAELDWARSV 176 + ++ R E+ RL+ + + + +L+ E+ V EL +S Sbjct: 215 ERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQ 274 Query: 177 VEHLKIGALR 186 +E ++ L Sbjct: 275 LEQIESEILS 284
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 26.6 bits (58), Expect = 0.050 Identities = 17/51 (33%), Positives = 26/51 (50%), Gaps = 9/51 (17%) Query: 61 DEIRTLLQLTDSPADPCDSVNTLLDEHIGHVDARLAELTHLRDQLTELRRQ 111 D I L+QL S +L+DEH+ +L ELT + ++L L R+ Sbjct: 689 DSIPLLIQLGRS---------SLMDEHLVEQREKLRELTTIAERLNRLERE 730
>cloacin#Cloacin signature. Length = 551 Score = 28.5 bits (63), Expect = 0.006 Identities = 14/34 (41%), Positives = 17/34 (50%) Query: 9 SGHGRGHVGGHGDGGHGGGHHGGAGREGHGGHEA 42 SG G GHG+GG G GG+G G+ A Sbjct: 52 SGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVA 85 Score = 26.6 bits (58), Expect = 0.027 Identities = 13/34 (38%), Positives = 14/34 (41%) Query: 9 SGHGRGHVGGHGDGGHGGGHHGGAGREGHGGHEA 42 SG G GG G G GG + G G G A Sbjct: 50 SGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSA 83
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 46.8 bits (111), Expect = 3e-08 Identities = 16/91 (17%), Positives = 32/91 (35%), Gaps = 1/91 (1%) Query: 17 ALALHQADRLEEAETLYRRILDADPRHADALHLLGLIGHQYGRYHEATELIMAAIEIKP- 75 A +Q+ + E+A +++ + D + LG G+Y A + Sbjct: 43 AFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIK 102 Query: 76 DATYYYNLGNVMQANNRPAAAAECFRLAIEL 106 + + ++ + A A LA EL Sbjct: 103 EPRFPFHAAECLLQKGELAEAESGLFLAQEL 133
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 181 bits (462), Expect = 3e-57 Identities = 80/336 (23%), Positives = 142/336 (42%), Gaps = 40/336 (11%) Query: 5 SVLVTGGAGFLGSHLCERLVHAGYDVMCVDNFHTGSKRNIEH----LIGRVNFEVIRHDV 60 LVTG AGF+G H+ +RL+ AG+ V+ +DN + +++ L+ + F+ + D+ Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 61 W-------LPLYVEADRVFNMACPASPVHYQ-SDPVSTVKTAVLGAINMLGLAKRCG-AR 111 L +RVF + V Y +P + + + G +N+L + Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLA-VRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 112 ILQASTSEVYGDAQQHPQQESYWGNVN-PNGLRACYDEGKRCAETLFFDYHRQHRVDIRV 170 +L AS+S VYG ++ P +V+ P L Y K+ E + Y + + Sbjct: 121 LLYASSSSVYGLNRKMPFSTD--DSVDHPVSL---YAATKKANELMAHTYSHLYGLPATG 175 Query: 171 VRIFNTYGPRMRADDGRVVSNFIMQALRGEPITLYGDGSQTRSFCYVDDLVEGLLRMMDQ 230 +R F YGP R D + F L G+ I +Y G R F Y+DD+ E ++R+ D Sbjct: 176 LRFFTVYGPWGRPD--MALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDV 233 Query: 231 DDDTGP------------------INLGNPSEITIRELAECVLRLTGSKSRIEYRPLPAD 272 N+GN S + + + + + G +++ PL Sbjct: 234 IPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQPG 293 Query: 273 DPLQRRPDIGRARQRLDWQPGIALEDGLKETIAHFR 308 D L+ D + + + P ++DG+K + +R Sbjct: 294 DVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYR 329
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 39.9 bits (93), Expect = 1e-05 Identities = 19/98 (19%), Positives = 34/98 (34%), Gaps = 1/98 (1%) Query: 38 PDAMHFLGLLACQLKQYDAGLVLMERSLAERP-DASYFNNVGNMLRECGRLDDAIAHYRR 96 + ++ L Q +Y+ + + D+ +F +G + G+ D AI Y Sbjct: 36 LEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSY 95 Query: 97 AVALRPDYPEAHNNLGNALRDARDPAEAMQSCSRAIEL 134 + P + L + AEA A EL Sbjct: 96 GAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQEL 133 Score = 32.2 bits (73), Expect = 0.004 Identities = 24/131 (18%), Positives = 39/131 (29%), Gaps = 7/131 (5%) Query: 237 SDDASLHNNYAGVLLDAGDLDAAAAHYARAIALDASLALAHANLSGVRRRQARYADALVH 296 SD + A +G + A + LD + L R+ +Y A+ Sbjct: 33 SDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHS 92 Query: 297 AQDAVRIAPDLADAHNQAGNAHHGLGDLVAAQACYRTALEL---NPADSGACHNLSVVL- 352 + A G+L A++ A EL +S +L Sbjct: 93 YSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQELIADKTEFKELSTRVSSMLE 152 Query: 353 ---LKRERHAE 360 LK+E E Sbjct: 153 AIKLKKEMEHE 163
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 51.9 bits (124), Expect = 1e-09 Identities = 19/86 (22%), Positives = 39/86 (45%) Query: 285 QQGEYEESLRLCRHAIELDPELADAYNFLGLAYHNLDRMAASELSHRHAIDLNPDDADAH 344 Q G+YE++ ++ + LD + + LG + + + S+ + ++ + Sbjct: 48 QSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKEPRFP 107 Query: 345 HNLAAALFRLDKLDEAMSEYRIAQEL 370 + A L + +L EA S +AQEL Sbjct: 108 FHAAECLLQKGELAEAESGLFLAQEL 133 Score = 40.7 bits (95), Expect = 5e-06 Identities = 20/98 (20%), Positives = 34/98 (34%), Gaps = 1/98 (1%) Query: 38 PDAMHFLGLLACQLKQYDAGLALMERSLAERP-DASYFNNLGNMLRECGRLDDAIAHYRR 96 + ++ L Q +Y+ + + D+ +F LG + G+ D AI Y Sbjct: 36 LEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSY 95 Query: 97 AVALRPDYPEAHNNLGNALRDARDPAEAMQSCSRAIEL 134 + P + L + AEA A EL Sbjct: 96 GAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQEL 133 Score = 31.8 bits (72), Expect = 0.006 Identities = 15/103 (14%), Positives = 33/103 (32%) Query: 301 ELDPELADAYNFLGLAYHNLDRMAASELSHRHAIDLNPDDADAHHNLAAALFRLDKLDEA 360 E+ + + L + + + + L+ D+ L A + + D A Sbjct: 30 EISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLA 89 Query: 361 MSEYRIAQELGVDPVKIQLTLGDILWAKRDFAGAVAAFREAVE 403 + Y + + + + L K + A A + A E Sbjct: 90 IHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQE 132
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 36.8 bits (85), Expect = 1e-04 Identities = 24/101 (23%), Positives = 43/101 (42%), Gaps = 5/101 (4%) Query: 10 NAAFVHHQAGRFDDARVLYEAIRRDEPDQPDATHFLGLLAC--QLGQFPAGLALMERAIA 67 + AF +Q+G+++DA +++A+ + FLGL AC +GQ+ + Sbjct: 41 SLAFNQYQSGKYEDAHKVFQALCVLDHYDSR--FFLGLGACRQAMGQYDLAIHSYSYGAI 98 Query: 68 LRA-DPVYLNNFGNMLRAHGRLDDAIGAYRRAIALAPDYAE 107 + +P + + L G L +A A L D E Sbjct: 99 MDIKEPRFPFHAAECLLQKGELAEAESGLFLAQELIADKTE 139 Score = 33.0 bits (75), Expect = 0.002 Identities = 20/110 (18%), Positives = 37/110 (33%) Query: 127 LSCAQALALRPDYAPAFNNLGNALQDKGELDAAARAYEKAIALDPGYAQARFNQGNVLRA 186 + A + D +L G+ + A + ++ LD ++ G +A Sbjct: 23 GTIAMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQA 82 Query: 187 QRRPDEAIASYREAIALQPDLHAAHHALGMLLFERDDLEAAVASLTRAAE 236 + D AI SY + L ++ +L A + L A E Sbjct: 83 MGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQE 132
>FLAGELLIN#Flagellin signature. Length = 507 Score = 97.8 bits (243), Expect = 3e-25 Identities = 96/268 (35%), Positives = 134/268 (50%), Gaps = 4/268 (1%) Query: 2 LNINTNILSLTTQTNLSGSQSALSQAINRLSSGKRVNTAADDAAGLAISTTQTAAINALT 61 INTN LSL TQ NL+ SQS+LS AI RLSSG R+N+A DDAAG AI+ T+ I LT Sbjct: 2 QVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLT 61 Query: 62 QGVANANNGISMIQTAAGALQSTVDNLQRIRTLAVESGDGSLDSNARANLQAEVTTRLGE 121 Q NAN+GIS+ QT GAL +NLQR+R L+V++ +G+ + ++Q E+ RL E Sbjct: 62 QASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEE 121 Query: 122 IDRVATQTTFNGQTILSNAGNVTFQVGASANQTVAVNFGATVWTSTGAGLSL----SGLT 177 IDRV+ QT FNG +LS + QVGA+ +T+ ++ S G T Sbjct: 122 IDRVSNQTQFNGVKVLSQDNQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKEAT 181 Query: 178 VSDQTSAQSAITAIDTALKNVNTFQATLGAAQNTFQAAITTTQTQATNMSAARSQITDAD 237 V D S+ +T DT N ++ + + T + +A TD Sbjct: 182 VGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTDDA 241 Query: 238 FATETANLSKAQVLQQAGISVLAQANSL 265 +L K A A ++ Sbjct: 242 ENNTAVDLFKTTKSTAGTAEAKAIAGAI 269 Score = 70.5 bits (172), Expect = 7e-16 Identities = 62/236 (26%), Positives = 107/236 (45%), Gaps = 3/236 (1%) Query: 39 TAADDAAGLAISTTQTAAINALTQGVANANNGISMIQTAAGALQSTVDNLQRIRTLAVES 98 D G+ + + + N + A + + +++ Sbjct: 275 GDTFDYKGVTFTIDTKTGNDGNGKVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVY 334 Query: 99 GDGSLDSNARANLQAEVTTRLGEIDRVATQTTFNGQTILSNAGNVTFQVGASANQTVAVN 158 + + +L ++ G++ ++ G A T+A Sbjct: 335 TSVVNGQFTFDDKTKNESAKLSDL---EANNAVKGESKITVNGAEYTANAAGDKVTLAGK 391 Query: 159 FGATVWTSTGAGLSLSGLTVSDQTSAQSAITAIDTALKNVNTFQATLGAAQNTFQAAITT 218 T++G ++ + + S + + +ID+AL V+ +++LGA QN F +AIT Sbjct: 392 TMFIDKTASGVSTLINEDAAAAKKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITN 451 Query: 219 TQTQATNMSAARSQITDADFATETANLSKAQVLQQAGISVLAQANSLPQQVLKLLQ 274 TN+++ARS+I DAD+ATE +N+SKAQ+LQQAG SVLAQAN +PQ VL LL+ Sbjct: 452 LGNTVTNLNSARSRIEDADYATEVSNMSKAQILQQAGTSVLAQANQVPQNVLSLLR 507
>BACYPHPHTASE#Salmonella/Yersinia modular tyrosine phosphatase signature. Length = 468 Score = 31.3 bits (70), Expect = 0.003 Identities = 26/75 (34%), Positives = 34/75 (45%), Gaps = 7/75 (9%) Query: 176 TEREAALAREADRVRAGRQRAHVELFAAKRPAAPPPARPRIELFGARGAGGAQTTTTKTA 235 + +AL VR G R+H++ + P PP RP G GAG A+ T T Sbjct: 133 SHSHSALHAPGTPVREG-LRSHLD---PRTPPLPPRERPHTS--GHHGAGEARATAPSTV 186 Query: 236 SPYAGSPTAANLSRK 250 SPY G A LS + Sbjct: 187 SPY-GPEARAELSSR 200
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 65.6 bits (160), Expect = 7e-14 Identities = 33/145 (22%), Positives = 64/145 (44%), Gaps = 15/145 (10%) Query: 5 QKIKVLCVDDSALIRSLMTEIINSQP-DMTVCATAPDPLVARDLIKQHNPDVLTLDVEMP 63 +L DD A IR+++ + ++ D+ + + A I + D++ DV MP Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAAT---LWRWIAAGDGDLVVTDVVMP 58 Query: 64 RMDGLDFLEKLMRLRP-MPVVMVSSLTERGSEITLRALELGAVDFVTKPRVGIRDGMLDY 122 + D L ++ + RP +PV+++S+ ++A E GA D++ KP D Sbjct: 59 DENAFDLLPRIKKARPDLPVLVMSAQNT--FMTAIKASEKGAYDYLPKP--------FDL 108 Query: 123 AEKLADKIRAASRARVRQTPQPQAA 147 E + RA + + R + + Sbjct: 109 TELIGIIGRALAEPKRRPSKLEDDS 133
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 88.3 bits (219), Expect = 1e-23 Identities = 33/110 (30%), Positives = 53/110 (48%), Gaps = 4/110 (3%) Query: 1 MDKSMKILVVDDFPTMRRIVRNLLKELGYTNVDEAEDGAAGLARLRGGGFDFVISDWNMP 60 M + ILV DD +R ++ L GY V + A + G D V++D MP Sbjct: 1 MTGA-TILVADDDAAIRTVLNQALSRAGYD-VRITSNAATLWRWIAAGDGDLVVTDVVMP 58 Query: 61 NLDGLAMLKEIRADATLTHLPVLMVTAESKKENIIAAAQAGASGYVVKPF 110 + + +L I+ LPVL+++A++ I A++ GA Y+ KPF Sbjct: 59 DENAFDLLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPF 106
>STREPKINASE#Streptococcus streptokinase protein signature. Length = 440 Score = 29.7 bits (66), Expect = 0.011 Identities = 37/146 (25%), Positives = 59/146 (40%), Gaps = 28/146 (19%) Query: 3 QPIHAALASAAFSADSHAEGADFASD-RILARIGQVTRALRDSMRELGLDKHVERAAEAV 61 + I L + S D + E DFASD I R G+V A +D Sbjct: 107 KAIQEQLIANVHSNDDYFEVIDFASDATITDRNGKVYFADKDGS---------------- 150 Query: 62 PDARDRLRYVATMTEQAAERVLNAIEIAKPVQER-IQNEAEALDARWTQWYAAPIEHAEV 120 V T+ E +L+ +P +E+ IQN+A+++D +T + + Sbjct: 151 ---------VTLPTQPVQEFLLSGHVRVRPYKEKPIQNQAKSVDVEYTVQFTPLNPDDDF 201 Query: 121 RELMDDTRTFLHALPDATSATSAQLL 146 R + DT+ L L + TS +LL Sbjct: 202 RPGLKDTK-LLKTLAIGDTITSQELL 226
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 364 bits (935), Expect = e-127 Identities = 105/350 (30%), Positives = 177/350 (50%), Gaps = 6/350 (1%) Query: 1 MADESDLDRTEAATPRRREKAREEGQVARSRELASFALLAAGFYGAWLLAAPSGAHLQAM 60 M+ E +TE TP++ AR++GQVA+S+E+ S AL+ A L+ H + Sbjct: 1 MSGE----KTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKL 56 Query: 61 LRGAFAFDRATAFDTHRMLSAAGSASIEGLAALLPILALTGLAALLAPMALGGWLISQKT 120 + +++ + + + +E P+L + L A+ + + G+LIS + Sbjct: 57 M--LIPAEQSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEA 114 Query: 121 FELKFDRLNPISGLGRIFSIQGPIQLGMSLAKTLVVGGIGGIAIWRSKDELLGLATQPFG 180 + ++NPI G RIFSI+ ++ S+ K +++ + I I + LL L T Sbjct: 115 IKPDIKKINPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIE 174 Query: 181 SAVADAMHLVAVCCGTTVAGMLVVAALDVPYQIWQYNKKLRMTKEEVKREHRENEGDPHV 240 ++ G +V++ D ++ +QY K+L+M+K+E+KRE++E EG P + Sbjct: 175 CITPLLGQILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEI 234 Query: 241 KGRIRQQQRAIARRRMMAAVPKADVVVTNPTHFAVALQYTDGEMRAPKVVAKGVNLVAAR 300 K + RQ + I R M V ++ VVV NPTH A+ + Y GE P V K + Sbjct: 235 KSKRRQFHQEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQT 294 Query: 301 IRELAAEHNVPLLEAPPLARALYHNVEIEREIPGSLYSAVAEVLAWVYQL 350 +R++A E VP+L+ PLARALY + ++ IP A AEVL W+ + Sbjct: 295 VRKIAEEEGVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQ 344
>PERTACTIN#Pertactin signature. Length = 922 Score = 34.3 bits (78), Expect = 6e-04 Identities = 27/92 (29%), Positives = 34/92 (36%) Query: 189 ALPGARLPGGAAPTLAGASGDDPFGGAGPLTGADDEVPRLAGTIRDARAGLALFDAGDGG 248 A+PG +PGG P L G G D L + E P+L IR R G Sbjct: 273 AVPGGAVPGGFGPLLDGWYGVDVSDSTVDLAQSIVEAPQLGAAIRAGRGARVTVSGGSLS 332 Query: 249 FATVARGEALGAARVMRVDADAVTLATADGAR 280 E G AR A +++ GAR Sbjct: 333 APHGNVIETGGGARRFPPPASPLSITLQAGAR 364
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 207 bits (529), Expect = 3e-61 Identities = 105/438 (23%), Positives = 177/438 (40%), Gaps = 46/438 (10%) Query: 133 GLAAAFDALARFTGLNIIVGEQVRGTVTLRLNNVRWRDAFDTLLDTHGLAMSRRGNVIWV 192 G AA L G++ TV L W A D + L + + Sbjct: 171 GRAAVIKRLLTIVERVDNAGDRSVVTVPLS-----WASAADVVKLVTELNKDTSKSALPG 225 Query: 193 TPATELAARER-------------ERFETHARAADLEPLA---SRTFALHYPRALDVQRL 236 + + A ER +R + D + ++ L Y +A D+ + Sbjct: 226 SMVANVVADERTNAVLVSGEPNSRQRIIAMIKQLDRQQATQGNTKVIYLKYAKASDLVEV 285 Query: 237 L-----------AGATGQRLLSKRGAAAADPRTNLLFVTDLAPRIVQIAGLIDAIDRPSR 285 L A L K A +TN L VT + + +I +D Sbjct: 286 LTGISSTMQSEKQAAKPVAALDKNIIIKAHGQTNALIVTAAPDVMNDLERVIAQLDIRRP 345 Query: 286 QVRIEARIVEGEQGFSRNLGARIALRAQGRAP---TADGAASATDTRNALDLAARPLGGF 342 QV +EA I E + NLG + A + G + ++A N + Sbjct: 346 QVLVEAIIAEVQDADGLNLGIQWANKNAGMTQFTNSGLPISTAIAGANQYNKDGTVSSSL 405 Query: 343 EAATAGFTLFAA-PLSRVLDVELSALEAQGRGQIVSSPRVVTADRVKAIVEQGSELPYQ- 400 +A + F AA + L+AL + + I+++P +VT D ++A G E+P Sbjct: 406 ASALSSFNGIAAGFYQGNWAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVPVLT 465 Query: 401 ----AKVGNGVSGVQFRRATLKLEVEPQITPDGRVVLDLDVTKDSIGEPTAA-----GPA 451 N + V+ + +KL+V+PQI V+L+++ S+ + ++ G Sbjct: 466 GSQTTSGDNIFNTVERKTVGIKLKVKPQINEGDSVLLEIEQEVSSVADAASSTSSDLGAT 525 Query: 452 IHTKHVQTRVEVENGGTVAIGGIYEQLNRDDVTRVPLLGKIPVLGALFRHRARRDQRSEL 511 +T+ V V V +G TV +GG+ ++ D +VPLLG IPV+GALFR +++ + L Sbjct: 526 FNTRTVNNAVLVGSGETVVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRNL 585 Query: 512 VVFITPTVVGTQCETSGA 529 ++FI PTV+ + E A Sbjct: 586 MLFIRPTVIRDRDEYRQA 603 Score = 65.3 bits (159), Expect = 3e-13 Identities = 49/292 (16%), Positives = 109/292 (37%), Gaps = 21/292 (7%) Query: 126 SLNLQGAGLAAAFDALARFTGLNIIVGEQVRGTVTLR----LNNVRWRDAFDTLLDTHGL 181 S + +G + + +++ +I+ VRGT+T+R LN ++ F ++LD +G Sbjct: 31 SASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRSYDMLNEEQYYQFFLSVLDVYGF 90 Query: 182 AMSRRGNVIWVTPATELAARERERFETHARAADLEPLASRTFALHYPRALDVQRLLAGAT 241 A+ N + ++ A + A + + +R L A D+ LL Sbjct: 91 AVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIGDEVVTRVVPLTNVAARDLAPLLRQLN 150 Query: 242 GQRLLSKRGAAAADPRTNLLFVTDLAPRIVQIAGLIDAIDRPSRQVRIEARIVEGEQGFS 301 + G+ +N+L +T A I ++ +++ +D + + + Sbjct: 151 DN---AGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDNAGDRSVVTVPLSWASAADV 207 Query: 302 RNLGARIALRAQGRA-PTADGAASATDTR-NALDLAARPLGGFEAATAGFTLFAAPLSRV 359 L + A P + A D R NA+ ++ P + + + Sbjct: 208 VKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSGEP-----NSRQRII----AMIKQ 258 Query: 360 LDVELSALEAQGRGQIVSSPRVVTADRVKAIVEQGSELPYQAKVGNGVSGVQ 411 LD + + QG +++ +D V+ + S + + + V+ + Sbjct: 259 LDRQQA---TQGNTKVIYLKYAKASDLVEVLTGISSTMQSEKQAAKPVAALD 307
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 27.5 bits (61), Expect = 0.028 Identities = 15/39 (38%), Positives = 21/39 (53%) Query: 51 ESQVIADLTQRENIVLATGGGAVLRAENRDCLKGHGIVI 89 E++ I L +R IV+A+GGG V +KG VI Sbjct: 175 EAETIKKLVERGVIVIASGGGGVPVILEDGEIKGVEAVI 213
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 40.9 bits (95), Expect = 8e-06 Identities = 46/192 (23%), Positives = 76/192 (39%), Gaps = 15/192 (7%) Query: 124 EKAFVPTIASYYSDA--KTGHLVSMPFNSSTPVLYYNKDAFKKAGLDPNQPPKTWADVQA 181 +KAF + + DA G L++ P L YNKD L PN PPKTW ++ A Sbjct: 108 DKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKD------LLPN-PPKTWEEIPA 160 Query: 182 DAEKLRKSGMACGFTTGWQGWIQLENYSVWHALPFASRNNGFDGADAVLEFNKPQQIAHI 241 ++L+ G + + + + F N +D D ++ + A + Sbjct: 161 LDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAK--AGL 218 Query: 242 AFLQQMQKDGTFTYAGRKDEASAKFYSGDCGILTTSSGALANVQKFAKFSYGTGMMPYDA 301 FL + K+ A A F G+ + A +N+ +K +YG ++P Sbjct: 219 TFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDT-SKVNYGVTVLP--- 274 Query: 302 NVKGAPQNAIIG 313 KG P +G Sbjct: 275 TFKGQPSKPFVG 286
>PF05272#Virulence-associated E family protein Length = 892 Score = 36.2 bits (83), Expect = 2e-04 Identities = 15/33 (45%), Positives = 19/33 (57%) Query: 33 VVLVGPSGCGKSTLLRMIAGLETVTDGEIAIGD 65 VVL G G GKSTL+ + GL+ +D IG Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGT 631
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 32.5 bits (74), Expect = 0.003 Identities = 75/368 (20%), Positives = 125/368 (33%), Gaps = 51/368 (13%) Query: 70 FMRPLGAIVLGAYADRAGRKAALTLSILLMMAGTLVIAVLPTYGTIGVAAPLILVAARLM 129 M+ A VLGA +DR GR+ L +S+ ++A P +L R++ Sbjct: 54 LMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFL--------WVLYIGRIV 105 Query: 130 QGFSAGGEFGSATAFLAEHVPGR-RGFFASWQVASQGLTTLLAAGFGTVLNAQLTADQMA 188 G + G A A++A+ G R + A G + G + M Sbjct: 106 AGIT-GATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGL---------MG 155 Query: 189 AWGWRIPFFFGLLLGPVAYYI-------RSKVDETPEFLAAESTATPLR--DTFASHKAR 239 + PFF L + + K + P A + R A Sbjct: 156 GFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAAL 215 Query: 240 LVAAMGVVVLGTV-ATYLVLFMPTYGVKQLGLAPSAAFAAILVVGVIQ-----MAFAPLV 293 + + ++G V A V+F G + + ++ G++ M P+ Sbjct: 216 MAVFFIMQLVGQVPAALWVIF----GEDRFHWDATTIGISLAAFGILHSLAQAMITGPVA 271 Query: 294 GHWSDRYGRVRVMIAPALGILVLIYPAFAYLVAHPGFGTLIALQVLLAFLMTGYFAALPG 353 +R + MIA G ++L + ++ + VLLA G AL Sbjct: 272 ARLGERRALMLGMIADGTGYILLAFATRGWMA--------FPIMVLLASGGIG-MPALQA 322 Query: 354 LLSEVFPVQTRTTGMSLAYNVAVTIFGG-FGPFIIAWLIRATGMKTAPSFYLMFAAVLSL 412 +LS V G A+T GP + + A+ + T + + A L L Sbjct: 323 MLSRQ--VDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAAS-ITTWNGWAWIAGAALYL 379 Query: 413 AALFVLRR 420 L LRR Sbjct: 380 LCLPALRR 387 Score = 29.8 bits (67), Expect = 0.022 Identities = 19/77 (24%), Positives = 37/77 (48%), Gaps = 5/77 (6%) Query: 240 LVAAMGVVVLGTVATYLVL-FMPTYGVKQLGLAPSAAFAAILVV---GVIQMAFAPLVGH 295 L+ + V L V L++ +P ++ L + +++ ++Q A AP++G Sbjct: 7 LIVILSTVALDAVGIGLIMPVLPGL-LRDLVHSNDVTAHYGILLALYALMQFACAPVLGA 65 Query: 296 WSDRYGRVRVMIAPALG 312 SDR+GR V++ G Sbjct: 66 LSDRFGRRPVLLVSLAG 82
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 319 bits (819), Expect = e-111 Identities = 94/316 (29%), Positives = 167/316 (52%), Gaps = 14/316 (4%) Query: 1 MEFFRIRKDIPFMRHALVFNVISLVTFLAAVFFLFHRGLHLSVEFTGGTVIEVQYQQAAQ 60 ++ + + F R ++V +A+V GL+ ++F GGT I + A Sbjct: 5 LKLVPEKTNFDFFRWQWATFGAAIVMMIASVILPLVIGLNFGIDFKGGTTIRTESTTAID 64 Query: 61 LEPVRATLGKLGYADAQVQNFGTSR------NVLIRLQLKEGLTSAQQ--------SDQV 106 + RA L L D + +IR+Q++E A+ ++V Sbjct: 65 VGVYRAALEPLELGDVIISEVRDPSFREDQHVAMIRIQMQEDGQGAEGQGAQGQELVNKV 124 Query: 107 MTALKAQSPDVSLQRVEFVGPQVGRELATDGLLALACVVIGIVIYLSIRFEWKYAVAGII 166 TAL A P + + E VGP+V EL + +L + I+ Y+ +RFEW++A+ ++ Sbjct: 125 ETALTAVDPALKITSFESVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGAVV 184 Query: 167 ANLHDVVIILGFFAFFQWEFSLAVLAAILAVLGYSVNESVVIFDRIRETFRRERRMSVSE 226 A +HDV++ +G FA Q +F L +AA+L + GYS+N++VV+FDR+RE + + M + + Sbjct: 185 ALVHDVLLTVGLFAVLQLKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRD 244 Query: 227 VINHAITTTMSRTIITHTSTEMMVLSMFFFGGPTLHYFALALTVGIMFGIYSSVFVAGSL 286 V+N ++ T+SRT++T +T + ++ M +GG + F A+ G+ G YSSV+VA ++ Sbjct: 245 VMNLSVNETLSRTVMTGMTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAKNI 304 Query: 287 AMWLGIKREDLIKDRK 302 +++G+ R KD Sbjct: 305 VLFIGLDRNKEKKDPS 320
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 79.5 bits (196), Expect = 3e-18 Identities = 53/249 (21%), Positives = 108/249 (43%), Gaps = 14/249 (5%) Query: 382 KGKGEVLTVATIQSELGDRFQITGQPTPQAAADLALLLRAGSLAAPMDIIEERTIGPSLG 441 + V + E G + G + + L A A + E ++GP + Sbjct: 91 REDQHVAMIRIQMQEDGQGAEGQGAQGQELVNKVETALTAVDPALKITSFE--SVGPKVS 148 Query: 442 ADNIKMGVHSVIWGFCAIAVFM-IAYYMLFGVISVIGLSVNLLLLVAVLSLMQATLTLPG 500 + + V S++ I ++ + + F + +V+ L ++LL V + +++Q L Sbjct: 149 GELVWTAVWSLLAATVVIMFYIWVRFEWQFALGAVVALVHDVLLTVGLFAVLQLKFDLTT 208 Query: 501 IAAIALALGMAIDSNVLINERVREELRA--GQPPQ----LAIQSGYAHAWATILDSNVTT 554 +AA+ G +I+ V++ +R+RE L P + L++ + T++ +TT Sbjct: 209 VAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRDVMNLSVNETLSR---TVMTG-MTT 264 Query: 555 LIAGLALLAFGSGPVRAFAIVHCLGILTSMFSAVFFSRGLVNLWYGGRKKLKSLAIGQVW 614 L+A + +L +G +R F G+ T +S+V+ ++ +V R K K + + Sbjct: 265 LLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAKNIVLFIGLDRNKEKKDPSDKFF 324 Query: 615 RPEGATAGA 623 GA GA Sbjct: 325 S-NGAQDGA 332
>SECA#SecA protein signature. Length = 901 Score = 34.8 bits (80), Expect = 0.002 Identities = 28/100 (28%), Positives = 40/100 (40%), Gaps = 6/100 (6%) Query: 367 AQARVVDEIAHDLTLPHPMQRLLQGDV-----GSGKTVVAALAATQAIDAGYQAALMAPT 421 A RV D+ L M L + + G GKT+ A L A G ++ Sbjct: 74 ASKRVFGMRHFDVQLLGGM-VLNERCIAEMRTGEGKTLTATLPAYLNALTGKGVHVVTVN 132 Query: 422 EILAEQHARKLRAWLEPLGVSVAWLAGSLKAKEKRAAIEA 461 + LA++ A R E LG++V + A KR A A Sbjct: 133 DYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAA 172
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 27.5 bits (61), Expect = 0.009 Identities = 6/26 (23%), Positives = 11/26 (42%) Query: 73 DYVHEHPWTSIGVAAGVGVLIGLLIN 98 + H PW + ++IG +N Sbjct: 6 ELAHGLPWLYFSLVFLFSLMIGSFLN 31
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 73.3 bits (180), Expect = 3e-16 Identities = 54/298 (18%), Positives = 108/298 (36%), Gaps = 44/298 (14%) Query: 285 VMVTGAGGSIGSELCRQILRFAPAQIVAFD-LSEYAMYRLTEELRERFPDQPVVPIIGDA 343 +VTGA G IG + +++L A Q+V D L++Y L + E D Sbjct: 3 YLVTGAAGFIGFHVSKRLLE-AGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 344 KDSLLLDQVMSRHAPHIVFHAAAYKHVPLMEEHNAWQALRNNVLGTYRVARAAIRHDVRH 403 D + + + VF + V E N +N+ G + + ++H Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLE-NPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 404 FVLIST---------------DKAVNPTNVMGASKRLAEMACQALQQTSGGTQFETVRFG 448 + S+ D +P ++ A+K+ E+ G +RF Sbjct: 121 LLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLY-GLPATGLRFF 179 Query: 449 NVLGSAGS---VIPKFQQQIAKGGPVTV-THPEITRFFMTIPEASQLVLQAS-------- 496 V G G + KF + + +G + V + ++ R F I + ++ +++ Sbjct: 180 TVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHADT 239 Query: 497 --SMGHGG--------EIFILDMGEPVRIVDLARDLIRLYGFSEGQIRIEFTGLRPGE 544 ++ G ++ + PV ++D + L G + + L+PG+ Sbjct: 240 QWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGI---EAKKNMLPLQPGD 294
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 45.2 bits (107), Expect = 5e-07 Identities = 21/100 (21%), Positives = 39/100 (39%), Gaps = 8/100 (8%) Query: 289 GGVKQLNFYVAPSFAWSNMALAINRAVTDNTARVVNMSIGGCENWAPTAAIDTLFELAVA 348 +K LN S + + I A+ +++MS+GG E+ + + AVA Sbjct: 113 LIIKVLN--KQGSGQYDWIIQGIYYAIEQK-VDIISMSLGGPED---VPELHEAVKKAVA 166 Query: 349 QGQTFAVSSGDSGSVAYGCSGTSVQYPATSPYVVAVGGTS 388 ++G+ G + YP V++VG + Sbjct: 167 SQILVMCAAGNEGD--GDDRTDELGYPGCYNEVISVGAIN 204
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 29.1 bits (65), Expect = 0.031 Identities = 14/50 (28%), Positives = 20/50 (40%), Gaps = 3/50 (6%) Query: 164 LASMVSFMMFASLAYVAFHVNDPVVMSASII-MMGAVLGFFLWNFPAGLI 212 L ++ MF V DP M I+ M + F FP+GL+ Sbjct: 467 LPILMGVTMFFIQKMSPTTVTDP--MQQKIMTFMPVIFTVFFLWFPSGLV 514
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 166 bits (422), Expect = 6e-51 Identities = 82/353 (23%), Positives = 148/353 (41%), Gaps = 54/353 (15%) Query: 6 TILVTGGAGYIGSHTAVELLDNGYDVVIVDNLVNSKAESVR--RIEKITGRTPAFHQVDV 63 LVTG AG+IG H + LL+ G+ VV +DNL + S++ R+E + FH++D+ Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 64 CDEAALAKVFDAHPITGTIHFAALKAVGESVAKPLEYYQNNIGGLLTVLKVMRERNVRQF 123 D + +F + AV S+ P Y +N+ G L +L+ R ++ Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 124 VFSSSATVYGVPERSPIDES----FPLSATNPYGQSKLMAEQV------LRDLEVSDPSW 173 +++SS++VYG+ + P P+S Y +K E + L L Sbjct: 122 LYASSSSVYGLNRKMPFSTDDSVDHPVS---LYAATKKANELMAHTYSHLYGL------- 171 Query: 174 RIATLRYFNPVGAHASGLIGEDPAGIPNNLMPYVAQVAVGKLEKLRVFGSDYPTPDGTGV 233 LR+F G P G P ++ + A+ + + + V+ G Sbjct: 172 PATGLRFFTVYG----------PWGRP-DMALFKFTKAMLEGKSIDVYN------YGKMK 214 Query: 234 RDYIHVVDLAKGHIAALDALATRDASF---------------VVNLGTGQGYSVLEVVRA 278 RD+ ++ D+A+ I D + D + V N+G +++ ++A Sbjct: 215 RDFTYIDDIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQA 274 Query: 279 FEKASGRPVPYELVARRPGDVAECYANPQAAADLIGWRATLGIDEMCADHWKW 331 E A G ++ +PGDV E A+ +A ++IG+ + + + W Sbjct: 275 LEDALGIEAKKNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNW 327
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 29.5 bits (66), Expect = 0.004 Identities = 12/35 (34%), Positives = 20/35 (57%), Gaps = 1/35 (2%) Query: 12 SLALFAAGLSAVAAPLAARADEILVGAPV-LVQSG 45 SL + L++V++ ++A A LVGAPV + Sbjct: 367 SLTTISTVLASVSSGISAAATTSLVGAPVSALVGA 401
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 30.3 bits (68), Expect = 0.017 Identities = 15/85 (17%), Positives = 23/85 (27%), Gaps = 5/85 (5%) Query: 478 APPAAAVEPARAAAPAAATGVTEPQDAAAAPADPLDTLREGDGREPDTAAADTDTDTGAT 537 PP VEP P P P + D + Sbjct: 68 PPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKP----KPKPKPVKKVEQPKRDVKPVES 123 Query: 538 HTPATPHDGSRPASGANGPAQPGST 562 PA+P + + PA + A ++ Sbjct: 124 -RPASPFENTAPARPTSSTATAATS 147
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 31.7 bits (72), Expect = 0.006 Identities = 26/114 (22%), Positives = 45/114 (39%), Gaps = 8/114 (7%) Query: 290 LLCFAVVFMGLATPLSAWASDRFGRKPVLIVGAIAALLSGFAMEPLLGSGSMPLVALFLT 349 L +A++ A L A SDRFGR+PVL+V A + ++ + V Sbjct: 49 LALYALMQFACAPVLGAL-SDRFGRRPVLLVSLAGAAVDYA----IMATAPFLWVLYIGR 103 Query: 350 LELFLMGVTFAPMGALLPELFP--TNVRYTG-AGVAYNLGGILGASIAPYIAQL 400 + + G T A GA + ++ R+ G + G + G + + Sbjct: 104 IVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGF 157
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 32.6 bits (74), Expect = 3e-04 Identities = 18/101 (17%), Positives = 32/101 (31%), Gaps = 1/101 (0%) Query: 4 AACTITPPPSAHSVVTIPSITRSGNLAQYRVEVARCVAEHNPSAVSRGPQAMLRSLVVVS 63 A A + + S + R ++ + P +R + V V Sbjct: 125 PASPFENTAPARPTSSTATAATSKPVT-SVASGPRALSRNQPQYPARAQALRIEGQVKVK 183 Query: 64 FTVDRGGRLVNASVYRSNGDSEAEALALASLRRSAPLPVPP 104 F V GR+ N + + + E ++RR P P Sbjct: 184 FDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKP 224
>ENTEROVIROMP#Enterobacterial virulence outer membrane protein signature. Length = 171 Score = 26.4 bits (58), Expect = 0.036 Identities = 24/109 (22%), Positives = 33/109 (30%), Gaps = 19/109 (17%) Query: 1 MKPFIASSLVA--LLATVGTHAAAADSASGADAQTPSCAIAYVKGVGGSPRGLR-----E 53 MK S +A L T GT AA + +G AQ+ +G G E Sbjct: 1 MKKIACLSALAAVLAFTAGTSVAATSTVTGGYAQS------DAQGQMNKMGGFNLKYRYE 54 Query: 54 YLASPT------PYNYLKENELQCKVSDDGRASNCTGVTYIRNEQVSVY 96 SP Y + + G Y N+ S+Y Sbjct: 55 EDNSPLGVIGSFTYTEKSRTASSGDYNKNQYYGITAGPAYRINDWASIY 103
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 27.6 bits (61), Expect = 0.032 Identities = 10/19 (52%), Positives = 11/19 (57%) Query: 160 GEYGFGYDPYFYLPSLGAT 178 G YG GY PY LP G+ Sbjct: 138 GHYGVGYGPYVQLPFYGSF 156
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 31.6 bits (71), Expect = 0.008 Identities = 11/79 (13%), Positives = 32/79 (40%), Gaps = 7/79 (8%) Query: 303 DINRFGFSPIEAYAWHRPLLAQHRDRYDPRVLSRILKGEPASAADYLDLLAARQAMLDEA 362 D +G +A + + ++ ++ + I + + DY+ +++ + D+ Sbjct: 581 DFYNYG------FALSNYMYNNNMGMFN-KMTNYIKNNDVSGYKDYIASMSSDYGLNDKY 633 Query: 363 AHTVWSRFDALVAPTVPVV 381 + S + + VP+V Sbjct: 634 QDYMDSLLNNIDNLDVPLV 652
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 32.1 bits (72), Expect = 0.004 Identities = 25/86 (29%), Positives = 31/86 (36%), Gaps = 2/86 (2%) Query: 2 SETTPSPAGLTGTPSASSRSPRSDPAHAPEVPATQPSVAQAAAAEDVAADGA-SPVTAAS 60 S P+ T S + + P AP PA + A A SPVTAA+ Sbjct: 152 STVLPTEKPTLFTKLTSEQLTTAQPDDAPGTPAQPLTPLVAEAQSKAEVISTPSPVTAAA 211 Query: 61 EPGAAGTTAAAEPAAAPPKVGAAPPG 86 P P A P V +AP G Sbjct: 212 SPLITPHQTQPLPTVAAP-VLSAPLG 236
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.4 bits (66), Expect = 0.011 Identities = 13/63 (20%), Positives = 27/63 (42%), Gaps = 1/63 (1%) Query: 148 QANRAQQLQADLSVARSQQAEVAQRQQSARQQTQALQVE-KRAAQVQLRDLQEQVRQLEK 206 Q N+ + +L V +SQ ++ SA+++ Q + K +LR + + L Sbjct: 257 QENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTL 316 Query: 207 QTE 209 + Sbjct: 317 ELA 319 Score = 28.3 bits (63), Expect = 0.025 Identities = 9/68 (13%), Positives = 23/68 (33%), Gaps = 1/68 (1%) Query: 141 LERVIALQANRAQQLQADLSVARSQQAEVAQRQQSARQQTQALQVEKRA-AQVQLRDLQE 199 E N + ++ L S+ + Q Q + ++K + L Sbjct: 257 QENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTL 316 Query: 200 QVRQLEKQ 207 ++ + E++ Sbjct: 317 ELAKNEER 324 Score = 27.5 bits (61), Expect = 0.046 Identities = 7/67 (10%), Positives = 20/67 (29%), Gaps = 1/67 (1%) Query: 141 LERVIALQANRAQQL-QADLSVARSQQAEVAQRQQSARQQTQALQVEKRAAQVQLRDLQE 199 + V + R L + S ++Q+ + R + + + R + Sbjct: 176 FQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKS 235 Query: 200 QVRQLEK 206 ++ Sbjct: 236 RLDDFSS 242
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 34.8 bits (80), Expect = 5e-04 Identities = 37/204 (18%), Positives = 57/204 (27%), Gaps = 43/204 (21%) Query: 239 VVIAGMGMVIMTTVSFYMITAYTPTFGKEVLHLSSLDALVVTVCVGLSNLVWLPLSGALS 298 V + +G+ ++ V ++ + H L A L P+ GALS Sbjct: 14 VALDAVGIGLIMPVLPGLLRDLVHS-NDVTAHYGILLA-----LYALMQFACAPVLGALS 67 Query: 299 DRIGRRPVLIA----FTVLTLLSAYPAVLWLVAEPSFLRLLAVELWLSFLYGSYNGAMVV 354 DR GRRPVL+ V + A LW+ L++ + GA Sbjct: 68 DRFGRRPVLLVSLAGAAVDYAIMATAPFLWV-------------LYIGRIVAGITGATGA 114 Query: 355 ALTEVM----PVDVRT-------AGFSLAYSLATTIGGFTPAISTLLIHQTGNKAAPGLW 403 + D R A F +GG S AP Sbjct: 115 VAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSP---------HAPFFA 165 Query: 404 LSVAALCGLIATLVLYRTPESRNQ 427 + + L + Sbjct: 166 AAALNGLNFLTGCFLLPESHKGER 189
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 49.5 bits (118), Expect = 4e-09 Identities = 21/83 (25%), Positives = 32/83 (38%) Query: 176 NLAMALNAMGRADDAIEHFQAAIAAQPRFVAAHFNLGNTFEALGRHDEAAAAFEAALALH 235 +LA G+ +DA + FQA LG +A+G++D A ++ + Sbjct: 41 SLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMD 100 Query: 236 PPFPLALFGLANALSALGRQREA 258 P F A L G EA Sbjct: 101 IKEPRFPFHAAECLLQKGELAEA 123 Score = 47.6 bits (113), Expect = 2e-08 Identities = 18/105 (17%), Positives = 37/105 (35%) Query: 28 LGTNPADADALHLFGVLRHQQGQHAEAADLVGRAVELRPGDAALQLNLGNALKALGRLDE 87 + + L+ ++Q G++ +A + L D+ L LG +A+G+ D Sbjct: 29 NEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDL 88 Query: 88 AIERFRNALTLAPEFPLAHYNLGNAYAALQRHEDAVDAFGRALRL 132 AI + + + P ++ +A A L Sbjct: 89 AIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQEL 133 Score = 47.2 bits (112), Expect = 3e-08 Identities = 19/105 (18%), Positives = 36/105 (34%), Gaps = 3/105 (2%) Query: 1 MDSAFDRAYAAHRAGRLAEAEHGYRAALGTNPADADALHLFGVLRHQQGQHAEAADLVGR 60 ++ + A+ +++G+ +A ++A + D+ G R GQ+ A Sbjct: 36 LEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSY 95 Query: 61 AVELRPGDAALQLNLGNALKALGRLDEAIERFRNALTLA---PEF 102 + + + L G L EA A L EF Sbjct: 96 GAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQELIADKTEF 140 Score = 46.5 bits (110), Expect = 5e-08 Identities = 20/105 (19%), Positives = 32/105 (30%) Query: 130 LRLTPDDASIHNNLGNALNALGRHDDALAAFHRALELRPGHAGAHNNLAMALNAMGRADD 189 ++ D +L G+++DA F L + L AMG+ D Sbjct: 29 NEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDL 88 Query: 190 AIEHFQAAIAAQPRFVAAHFNLGNTFEALGRHDEAAAAFEAALAL 234 AI + + F+ G EA + A L Sbjct: 89 AIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQEL 133 Score = 43.4 bits (102), Expect = 6e-07 Identities = 25/127 (19%), Positives = 46/127 (36%), Gaps = 10/127 (7%) Query: 88 AIERF-RNALTLA------PEFPLAHYNLGNAYAALQRHEDAVDAFGRALRLTPDDASIH 140 A+E F + T+A + Y+L ++EDA F L D+ Sbjct: 14 AMESFLKGGGTIAMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFF 73 Query: 141 NNLGNALNALGRHDDALAAFHRALELRPGHAGAHNNLA---MALNAMGRADDAIEHFQAA 197 LG A+G++D A+ ++ + + A + + A+ + Q Sbjct: 74 LGLGACRQAMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQEL 133 Query: 198 IAAQPRF 204 IA + F Sbjct: 134 IADKTEF 140 Score = 39.5 bits (92), Expect = 1e-05 Identities = 16/70 (22%), Positives = 30/70 (42%) Query: 253 GRQREALPYYERAVGLDPSFSLAWLNLGNAHHALGAHEMALRAFDQALRVAPDLKLAQLH 312 G+ +A ++ LD S +L LG A+G +++A+ ++ + H Sbjct: 50 GKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKEPRFPFH 109 Query: 313 RAVTLLTLGD 322 A LL G+ Sbjct: 110 AAECLLQKGE 119 Score = 38.4 bits (89), Expect = 3e-05 Identities = 17/97 (17%), Positives = 30/97 (30%) Query: 209 FNLGNTFEALGRHDEAAAAFEAALALHPPFPLALFGLANALSALGRQREALPYYERAVGL 268 ++L G++++A F+A L GL A+G+ A+ Y + Sbjct: 40 YSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIM 99 Query: 269 DPSFSLAWLNLGNAHHALGAHEMALRAFDQALRVAPD 305 D + G A A + D Sbjct: 100 DIKEPRFPFHAAECLLQKGELAEAESGLFLAQELIAD 136
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 28.2 bits (63), Expect = 0.020 Identities = 26/132 (19%), Positives = 43/132 (32%), Gaps = 26/132 (19%) Query: 4 KVLLIGATGRTGQACADLLLKQPEFEVTAL-------------VRRHGYALPGAKVVEAD 50 K L+ GA G G + LL+ +V + R A PG + + D Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGH-QVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 51 LT-GDF------SHAFQGITHVIYAAG---SAESEGAAEEEQIDRDAVARAAEHALAYNV 100 L + S F+ + + S E+ A + + E + Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNL--TGFLNILEGCRHNKI 118 Query: 101 QKLVVISSLTAY 112 Q L+ SS + Y Sbjct: 119 QHLLYASSSSVY 130
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 48.5 bits (115), Expect = 5e-08 Identities = 35/186 (18%), Positives = 61/186 (32%), Gaps = 6/186 (3%) Query: 322 AVQESVQADAQEAAVVD---VTDEVALVPAATAEATVVT---EATEVADTHGDAKDGRKR 375 A SV ++ +E A VD V P+ T E E+ V DA + + Sbjct: 1005 ADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQ 1064 Query: 376 ARKSAAKKTGAKKGGEAKGAGRQAAAKPDEAAHGGAKHGGDKHAQGMPAEATHRDMEHRE 435 R+ A + K Q+ ++ E K + T + E + Sbjct: 1065 NREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPK 1124 Query: 436 ERHVAAPTAGEYGAPAAAAQPAPEAAPAAESTGEAAGEAAAAKPKKPARKTAPRARRPRK 495 +P + A+PA E P + A ++PA++T+ +P Sbjct: 1125 VTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVT 1184 Query: 496 TATAAE 501 +T Sbjct: 1185 ESTTVN 1190
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 68.3 bits (167), Expect = 5e-15 Identities = 77/368 (20%), Positives = 121/368 (32%), Gaps = 64/368 (17%) Query: 1 MKTFRTAATAVSLAAAAASPGAHAQSSVTLYGIVDTGIQYYNNAAGGGAVAGMPSLTGEV 60 MK A T +L AA + VTLYG + G++ + A GA A + Sbjct: 1 MKKSLIALTLAALPVAAMA-------DVTLYGTIKAGVETSRSVAHNGAQAASVETGTGI 53 Query: 61 P---SRFGLRGVEDLGGGYRAFFVLENGFAPNSGALNYGGRLFGRQANVGIESPYGALTL 117 S+ G +G EDLG G +A + +E + RQ+ +G++ +G L + Sbjct: 54 VDLGSKIGFKGQEDLGNGLKAIWQVEQ----KASIAGTDSGWGNRQSFIGLKGGFGKLRV 109 Query: 118 GRQMNMSMRVLLNADVIGP--------SIHSMASFDSYLPNARSDNALGYLGRFGGVTLG 169 GR + VL + I P ++ +A ++ L + R D+ F G++ Sbjct: 110 GRLNS----VLKDTGDINPWDSKSDYLGVNKIAEPEARLISVRYDSP-----EFAGLSGS 160 Query: 170 GTYSTGRDDAGPAGPSATHCAGNVAGDPVACRQYTMMVAYDAPQFGAAASY--------D 221 Y+ D+AG Y Y F Sbjct: 161 VQYA-LNDNAGRHNS----------------ESYHAGFNYKNGGFFVQYGGAYKRHHQVQ 203 Query: 222 VMHGGAGASAPLSSPGYTDTRTIVDAYVKFGIAKLGAGWIRRNTAAAAHSQSDIFFAGGT 281 GY + V+ AKL N+ + F Sbjct: 204 ENVNIEKYQIHRLVSGYDNDALYASVAVQQQDAKLVEENYSHNSQTEVAATLAYRFGN-- 261 Query: 282 VQATPALSFDAQALRYLLRGRFDSNL---FVARANYSLSKRTMVYTSVGYMTNSALGTSA 338 TP +S+ A + +N V A Y SKRT S G++ + Sbjct: 262 --VTPRVSY-AHGFKGSFDATNYNNDYDQVVVGAEYDFSKRTSALVSAGWLQEGKGESKF 318 Query: 339 VAAGGTVG 346 V+ G VG Sbjct: 319 VSTAGGVG 326
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 762 bits (1969), Expect = 0.0 Identities = 275/1102 (24%), Positives = 505/1102 (45%), Gaps = 95/1102 (8%) Query: 3 LSRPFITRPVATTLLALGVALAGLFAFIKLPVSPLPQVDFPTISVQASLPGASPETVATS 62 ++ FI RP+ +LA+ + +AG A ++LPV+ P + P +SV A+ PGA +TV + Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 63 VTSPLERHLGSIADVSEMTSTST-VGNARIILQFGLNRDIDGAARDVQAAINAARADLPA 121 VT +E+++ I ++ M+STS G+ I L F D D A VQ + A LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 122 SLKSNPTYRKVNPADSPIMIVSLTSET--SSPAKLYDAASTVLQQSLSQIDGIGQVSVSG 179 ++ + S +M+ S+ ++ + D ++ ++ +LS+++G+G V + G Sbjct: 121 EVQ-QQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG 179 Query: 180 SANPAVRVELEPHALFHYGIGLEDVRAALASANANSPKGAIEFGPK------HYQLYTND 233 + A+R+ L+ L Y + DV L N G + P + + Sbjct: 180 AQY-AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQT 238 Query: 234 QASHASQYSDLVV-AYRNGAAVRLSDLSEVVDSVEDLRNLGLSNGKRAVLVILYRSPGAN 292 + + ++ + + +G+ VRL D++ V E+ + NGK A + + + GAN Sbjct: 239 RFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGAN 298 Query: 293 IIETIDRVRTALPQLTASLPADITVTPVLDRSTTIRASLKDTEHTLLIAISLVVMVVFLF 352 ++T ++ L +L P + V D + ++ S+ + TL AI LV +V++LF Sbjct: 299 ALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLF 358 Query: 353 LRNWRATLIPSVAVPISIIGTFGAMYLLGFSIDNLSLMALIVATGFVVDDAIVVLENITR 412 L+N RATLIP++AVP+ ++GTF + G+SI+ L++ +++A G +VDDAIVV+EN+ R Sbjct: 359 LQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 418 Query: 413 HI-ENGKPRLQAAFDGAREVGFTVLSMSISLVAVFLPILLMGGIVGRLFREFALTLSLAI 471 + E+ P +A ++ ++ +++ L AVF+P+ GG G ++R+F++T+ A+ Sbjct: 419 VMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAM 478 Query: 472 AVSLAVSLTVTPMMCARLLREPHDAHEE--GRLGRFLERFFARMQRGYERSLSWALRRPL 529 A+S+ V+L +TP +CA LL+ H E G + F Y S+ L Sbjct: 479 ALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTG 538 Query: 530 LVLLILFATIGLNVYLYIIVPKGFFPQQDTGLMIGGIRADQSTSFQAMKQKFTEMMRIVQ 589 LLI + V L++ +P F P++D G+ + I+ + + ++ ++ Sbjct: 539 RYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYL 598 Query: 590 SN--PNVQSAAGFTG----GTQTNSGFMFVTLKDRTER---KLSADQVIQQLRKPLADVA 640 N NV+S G G N+G FV+LK ER + SA+ VI + + L + Sbjct: 599 KNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIR 658 Query: 641 GASTFLQAAQDIRVGGRQSNAQYQFT-LLGDSSTDLYKWGP-LLTEALQKRAELTDVNSD 698 I G + ++ G L + LL A Q A L V + Sbjct: 659 DGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPN 718 Query: 699 QQQGGLEAMVTIDRATAARLGIKPAQIDNTLYDAFGQRQVSTIYNPLNQYHVVMEVAPKY 758 + + + +D+ A LG+ + I+ T+ A G V+ + + ++ K+ Sbjct: 719 GLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKF 778 Query: 759 WQSPQMLNEVWISTSGGSANGSQSTNAAAGTFVATSAGTSSAGTAATSAAAIASDSARNQ 818 P+ ++++++ + A G V S A + Sbjct: 779 RMLPEDVDKLYVRS-------------ANGEMVPFS--------------AFTTSHWVYG 811 Query: 819 ALNSIASSGKSSASSGAAVSTSKSTMIPLSAIATFGPSTTPLSVNHQGLFVATTISFNLP 878 + +G S + S+ ++ + ++ LP Sbjct: 812 SPRLERYNGLPSMEIQGEAAPGTSSGDAMALME--------------------NLASKLP 851 Query: 879 PGVSLSQATQAIYQTMAQIGVPPTIVGSFQGTAQAFQQSLNNQPILILAALLAVYIVLGI 938 G+ + G + + S N P L+ + + V++ L Sbjct: 852 AGIGY----------------------DWTGMSYQERLSGNQAPALVAISFVVVFLCLAA 889 Query: 939 LYESYIHPITILSTLPSAGVGALLALLLFKTEFSIIALIGVILLIGIVKKNAIMMVDFAI 998 LYES+ P++++ +P VG LLA LF + + ++G++ IG+ KNAI++V+FA Sbjct: 890 LYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAK 949 Query: 999 DQTRNGNKSSFDAIHEACLLRFRPIMMTTMAALLGALPLAFGHGDGAELRAPLGIAIAGG 1058 D K +A A +R RPI+MT++A +LG LPLA +G G+ + +GI + GG Sbjct: 950 DLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGG 1009 Query: 1059 LIMSQVLTLYTTPVVYLYMDRL 1080 ++ + +L ++ PV ++ + R Sbjct: 1010 MVSATLLAIFFVPVFFVVIRRC 1031 Score = 97.2 bits (242), Expect = 2e-22 Identities = 82/507 (16%), Positives = 169/507 (33%), Gaps = 33/507 (6%) Query: 2 NLSRPFITRPVATTLLALGVALAGLFAFIKLPVSPLPQVDFPTISVQASLP-GASPETVA 60 N + L+ + + F++LP S LP+ D LP GA+ E Sbjct: 528 NSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQ 587 Query: 61 TSVTSPLERHLGSIAD-------VSEMTSTSTVGNARIIL-QFGLNRDIDGAARDVQAAI 112 + + +L + V+ + + NA + + +G +A I Sbjct: 588 KVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVI 647 Query: 113 NAARADLPASLKSNPTYRKVNPADSPIMIVSLTSETS-----SPAKLYDAASTVLQQSLS 167 + A+ +L + E L A + +L + Sbjct: 648 HRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQ 707 Query: 168 QIDGIGQVSVSGSAN-PAVRVELEPHALFHYGIGLEDVRAALASANANSPKGAIEFGPKH 226 + V +G + ++E++ G+ L D+ +++A + + Sbjct: 708 HPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRV 767 Query: 227 YQLYT---NDQASHASQYSDLVVAYRNGAAVRLSDLSEVVDSVEDLRNLGLSNGKRAVLV 283 +LY L V NG V S + V L NG ++ + Sbjct: 768 KKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHW-VYGSPRLERYNGLPSMEI 826 Query: 284 ILYRSPGANIIETIDRVRTALPQLTASLPADITVTPVLDRSTTIRASLKDTEHTLLIAIS 343 +PG + + + L + LPA I T + + + + ++ Sbjct: 827 QGEAAPGTSSGD----AMALMENLASKLPAGIGYD-----WTGMSYQERLSGNQAPALVA 877 Query: 344 LVVMVVFLFL----RNWRATLIPSVAVPISIIGTFGAMYLLGFSIDNLSLMALIVATGFV 399 + +VVFL L +W + + VP+ I+G A L D ++ L+ G Sbjct: 878 ISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLS 937 Query: 400 VDDAIVVLENIT-RHIENGKPRLQAAFDGAREVGFTVLSMSISLVAVFLPILLMGGIVGR 458 +AI+++E + GK ++A R +L S++ + LP+ + G Sbjct: 938 AKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSG 997 Query: 459 LFREFALTLSLAIAVSLAVSLTVTPMM 485 + + + + +++ P+ Sbjct: 998 AQNAVGIGVMGGMVSATLLAIFFVPVF 1024 Score = 63.3 bits (154), Expect = 4e-12 Identities = 37/225 (16%), Positives = 84/225 (37%), Gaps = 3/225 (1%) Query: 870 ATTISFNLPPGVSLSQATQAIYQTMAQI--GVPPTI-VGSFQGTAQAFQQSLNNQPILIL 926 A + L G + +AI +A++ P + V T Q S++ + Sbjct: 286 AAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLF 345 Query: 927 AALLAVYIVLGILYESYIHPITILSTLPSAGVGALLALLLFKTEFSIIALIGVILLIGIV 986 A++ V++V+ + ++ + +P +G L F + + + G++L IG++ Sbjct: 346 EAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLL 405 Query: 987 KKNAIMMVDFAIDQTRNGNKSSFDAIHEACLLRFRPIMMTTMAALLGALPLAFGHGDGAE 1046 +AI++V+ +A ++ ++ M +P+AF G Sbjct: 406 VDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGA 465 Query: 1047 LRAPLGIAIAGGLIMSQVLTLYTTPVVYLYMDRLRVWGEKRRNRR 1091 + I I + +S ++ L TP + + + Sbjct: 466 IYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGG 510
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 810 bits (2094), Expect = 0.0 Identities = 287/1036 (27%), Positives = 495/1036 (47%), Gaps = 29/1036 (2%) Query: 4 SRLFILRPVGTALLMAAIMLAGLVALRFLPLAALPEVDYPTIQVQTFYPGASPEVMTSSV 63 + FI RP+ +L +M+AG +A+ LP+A P + P + V YPGA + + +V Sbjct: 2 ANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTV 61 Query: 64 TAPLERQFGQMPSLNQMSSQS-SAGASVITLQFSLDLPLDIAEQEVQAAINAAGNLLPSD 122 T +E+ + +L MSS S SAG+ ITL F DIA+ +VQ + A LLP + Sbjct: 62 TQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE 121 Query: 123 LPAPPIYAKVNPADAPVLTLAITSKTLPLTQ--VQDLTDTRLAMKISQIAGVGLVSLSGG 180 + I + + ++ S TQ + D + + +S++ GVG V L G Sbjct: 122 VQQQGIS-VEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 NRPAVRIQANPTALAQYGMNLDDLRTTISNLNVNTPKGNFDGP------TRAYTINANDQ 234 A+RI + L +Y + D+ + N G G +I A + Sbjct: 181 QY-AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 235 LTSADQY-NSAVVAYKSGRPVMLTDVAKVVAGSENTKLGAWVNAEPAIILNVQRQPGANV 293 + +++ + G V L DVA+V G EN + A +N +PA L ++ GAN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 294 IATVDAIKAQLPKLQETLPAALDVQIVTDRTTMIRAAVRDVQFELLLAVALVVLVMYLFL 353 + T AIKA+L +LQ P + V D T ++ ++ +V L A+ LV LVMYLFL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 354 ANVYATIIPSLSVPLSLIGTLAVMYLAGFSLNNLSLMALTIATGFVVDDAIVMIENIARY 413 N+ AT+IP+++VP+ L+GT A++ G+S+N L++ + +A G +VDDAIV++EN+ R Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 414 VEEGHT-GLEAALKGSRQIGFTIISLTVSLIAVLIPLLFMGDVVGRLFHEFAITLAVTIV 472 + E EA K QI ++ + + L AV IP+ F G G ++ +F+IT+ + Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 473 ISAIVSLTLVPMMCAKLLRHSPPPESH---RFEARVHRVIDRVIARYGVALEWVLNRQGS 529 +S +V+L L P +CA LL+ F + D + Y ++ +L G Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 530 TLVVALLTLALTALLYVYVPKGFFPAQDTGVIQAITQAPQSISYGAMAERQQALAAEILK 589 L++ L +A +L++ +P F P +D GV + Q P + + + LK Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 590 D--PNVESLTSFIGVDGSNITLNSGRMLINLKARDHRS---ESSAQIIRDLQQRVANVTG 644 + NVES+ + G S N+G ++LK + R+ S+ +I + + + Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRD 659 Query: 645 ITLFMQSVQDLTIDSTVSPTQYQFMLTS---PNPDEFATWVPKLVTRLQKEPS-LADVAT 700 F+ I + T + F L D +L+ + P+ L V Sbjct: 660 --GFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRP 717 Query: 701 DLQSNGQSVYIEIDRASAARFGITPATVDNALYDAFGQRIVSTIFTQSNQYRVILESEPK 760 + + +E+D+ A G++ + ++ + A G V+ + ++ ++++ K Sbjct: 718 NGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAK 777 Query: 761 EQHYAESLNDIYLPSAGGGQVPLSSIASFHERPSPLLIAHLSQFPSTTISFNLAPGASLG 820 + E ++ +Y+ SA G VP S+ + H + + PS I APG S G Sbjct: 778 FRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSG 837 Query: 821 EAVKAIGAAEKDIGLPGSFQTRFQGAALAFQASLSNQLFLILAAVVTMYIVLGVLYESYI 880 +A+ + LP + G + + S + L+ + V +++ L LYES+ Sbjct: 838 DAMALMENLASK--LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWS 895 Query: 881 HPITILSTLPSAGVGALLALMITGHDLDIIGIIGIVLLIGIVKKNAIMMIDFALEAERVE 940 P++++ +P VG LLA + D+ ++G++ IG+ KNAI++++FA + E Sbjct: 896 IPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKE 955 Query: 941 GKPPREAIYQACLLRFRPILMTTLAALLGAVPLIVGAGAGSELRQPLGIAIAGGLIVSQV 1000 GK EA A +R RPILMT+LA +LG +PL + GAGS + +GI + GG++ + + Sbjct: 956 GKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATL 1015 Query: 1001 LTLFTTPVIYLGFDSL 1016 L +F PV ++ Sbjct: 1016 LAIFFVPVFFVVIRRC 1031
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 50.6 bits (121), Expect = 8e-09 Identities = 32/166 (19%), Positives = 62/166 (37%), Gaps = 28/166 (16%) Query: 73 PAAMANIPQPVS-----------------VATATQGEMPIVLSALGTVTPLANV-TVKTQ 114 PA + I PVS + G++ IV +A G +T +K Sbjct: 43 PAHLELIETPVSRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPI 102 Query: 115 LSGYLQSVAFQEGQLVKKGDLLAQIDPRP-------YQVALENAEGTHARDAALLATARL 167 + ++ + +EG+ V+KGD+L ++ Q +L A R L + L Sbjct: 103 ENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIEL 162 Query: 168 DLKRYQTLLSQ---DSIASQTVDTQASLVKQYEGTVKTDQAAIDSA 210 + L + +++ + V SL+K+ T + + + Sbjct: 163 NKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELN 208 Score = 34.4 bits (79), Expect = 0.001 Identities = 22/139 (15%), Positives = 43/139 (30%), Gaps = 4/139 (2%) Query: 106 LANVTVKTQLSGYLQSVAFQEGQLVKKGDLLAQIDPRPYQVALENAEGTHARDAALLATA 165 LA + LS +S L+ K +A+ + A + L Sbjct: 220 LARINRYENLSRVEKSRLDDFSSLLHKQ-AIAKHAVLEQENKYVEAVNELRVYKSQLEQI 278 Query: 166 RLDLKRYQTLLSQDSIASQTVDTQASLVKQYEGTVKTDQAAIDSAKLNLTYARITAPVSG 225 ++ + + + ++Q + + + + I APVS Sbjct: 279 ESEILSAKEEYQL--VTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSV 336 Query: 226 RV-GLRQVDPGNYVTAGDT 243 +V L+ G VT +T Sbjct: 337 KVQQLKVHTEGGVVTTAET 355
>NEISSPPORIN#Neisseria sp. porin signature. Length = 348 Score = 30.3 bits (68), Expect = 0.006 Identities = 15/35 (42%), Positives = 22/35 (62%) Query: 57 SRITATLVSAGFLFQLPDSERFVLTASVLELSHGF 91 S+ T+ LVSAG+L +++ V TAS + L H F Sbjct: 314 SKRTSALVSAGWLQGGKGADKIVSTASAVVLRHKF 348
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.4 bits (66), Expect = 0.014 Identities = 14/77 (18%), Positives = 34/77 (44%), Gaps = 16/77 (20%) Query: 138 AAGSPV--LAAAPGTVVYAGNGLRGYGNLIILKHNADYLTAYAHNRALLVKEGQSVTQGQ 195 + V +A A G + ++G +K + + + ++VKEG+SV +G Sbjct: 75 SVLGQVEIVATANGKLTHSGR-------SKEIKPIENSIV-----KEIIVKEGESVRKGD 122 Query: 196 TIAEM--GNSDSDRVAL 210 + ++ +++D + Sbjct: 123 VLLKLTALGAEADTLKT 139
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 73.7 bits (181), Expect = 2e-17 Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 2/122 (1%) Query: 2 KILLVEDNQQVAGFLKKGLLETGHVVDWADNGRDGMALAIGESYDAIVLDRMLPGGIDGL 61 IL+ +D+ + L + L G+ V N D +V D ++P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE-NAF 63 Query: 62 KIVAALRAAGSKVPVLILSALDEVDERIRGLKAGGDDYVVKPFSFGEVVARLE-ALARRS 120 ++ ++ A +PVL++SA + I+ + G DY+ KPF E++ + ALA Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 121 QD 122 + Sbjct: 124 RR 125
>PF06580#Sensor histidine kinase Length = 349 Score = 41.4 bits (97), Expect = 3e-05 Identities = 32/225 (14%), Positives = 80/225 (35%), Gaps = 37/225 (16%) Query: 1446 SLENASLEEKHALLAEKDALLHEVHHRVK-----NNLQLISSLLNLQAERVTN--KAVAE 1498 + + A +++ ++A L + ++ N L I +L+ + +++E Sbjct: 143 NYKQAEIDQWKMASMAQEAQLMALKAQINPHFMFNALNNIRALILEDPTKAREMLTSLSE 202 Query: 1499 LFADSRNRVRSMAM-VHENLYRAGNFARIAMTAHVKTLCGHLARVYDMGRLG--VDLQID 1555 L S + + + + L ++ ++A + + + Sbjct: 203 LMRYSLRYSNARQVSLADELTVVDSYLQLASI-----------------QFEDRLQFENQ 245 Query: 1556 VDDIQLDMNRAVSCGLVINELVSNALKHAFPDQRGGVLKVELKAI-DDQRCALIVADDGV 1614 ++ + +++ LV N +KH G K+ LK D+ L V + G Sbjct: 246 INP---AIMDVQVPPMLVQTLVENGIKHGIAQLPQGG-KILLKGTKDNGTVTLEVENTGS 301 Query: 1615 GLAPGFSFERDETLGLRLVHDLVLQLRG---RIDIAQQHGTTFTI 1656 + + GL+ V + + L G +I ++++ G + Sbjct: 302 LALK--NTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAM 344
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 82.6 bits (204), Expect = 2e-18 Identities = 48/170 (28%), Positives = 77/170 (45%), Gaps = 19/170 (11%) Query: 787 ILVVDDVPANRTLLAEVLGQAGFRVIESSDGRDALDKAAACAPDLIVLDTVMPVMGGIET 846 ILV DD A RT+L + L +AG+ V +S+ AA DL+V D VMP + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 847 LRHLRRSQTLGATPVIVVSADASEQNARANIDAGANVFLEKPLNLDRLLGSIAMLLGLVT 906 L +++++ PV+V+SA + A + GA +L KP +L L+G I L Sbjct: 66 LPRIKKARP--DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 907 LQGAGPACEANRPMIIPPREDMAALHRYALLG---SMRDISRHADRLASS 953 + P + + + L+G +M++I R RL + Sbjct: 124 RR--------------PSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQT 159 Score = 75.6 bits (186), Expect = 3e-16 Identities = 42/145 (28%), Positives = 68/145 (46%), Gaps = 9/145 (6%) Query: 1 MTSAQILIVEDDRIVARDIAQQMSRAGYVVVGSTGSGEEALALVETLPAGSKPDLVLMDV 60 MT A IL+ +DD + + Q +SRAGY V T + + DLV+ DV Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVR-ITSNAATLWRWIAAGD----GDLVVTDV 55 Query: 61 RLEGELDGIDTARCIREAR-DIPVVFLTAYADEETIRRATAAEPYGYVLKPFDDMQLRTV 119 + E + D I++AR D+PV+ ++A T +A+ Y Y+ KPFD +L + Sbjct: 56 VMPDE-NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGI 114 Query: 120 VEMAL--YKHGAERRLRESEQRYAI 142 + AL K + +S+ + Sbjct: 115 IGRALAEPKRRPSKLEDDSQDGMPL 139
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 29.8 bits (67), Expect = 0.034 Identities = 46/261 (17%), Positives = 90/261 (34%), Gaps = 13/261 (4%) Query: 76 AIFILPFVLFSATSGQIADKYDKATLTRFVKTFEIALMLVGAAGF-VTHSATLLYLCTFM 134 A++ L + G ++D++ + R V +A V A +LY+ + Sbjct: 50 ALYALMQFACAPVLGALSDRFGR----RPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIV 105 Query: 135 MGMHSTLFGPVKYSYLPQHLGEHELVGGNGLVEMGTFIAILIGTIIGGAAAGIEGSGERV 194 G+ + G V +Y+ E G + ++ G ++GG G Sbjct: 106 AGI-TGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFF 164 Query: 195 LAVSVVVIALAGRLVAQRVPPTPAPQPDLVINWNPFSETWRNLGLAKQNRTVFLSLLGIS 254 A ++ + +P NP + G+ TV +L+ + Sbjct: 165 AAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGM-----TVVAALMAVF 219 Query: 255 WL-WFVGATFLTSFFNFAKDVLSASPDVVTVLLATFSV-GIGLGSLLCERLSQRRVEIGL 312 ++ VG + F +D + + LA F + +++ ++ R E Sbjct: 220 FIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRA 279 Query: 313 VPLGSIGISVFAIELYFASRS 333 + LG I I L FA+R Sbjct: 280 LMLGMIADGTGYILLAFATRG 300
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 58.4 bits (141), Expect = 2e-11 Identities = 66/409 (16%), Positives = 144/409 (35%), Gaps = 78/409 (19%) Query: 34 LDRGTLAVASSAIRSDLGLSLSEMGLLLSAFSWSYALCQFPVGGLVDRIGPRRLLGVGLI 93 L+ L V+ I +D + + +AF ++++ G L D++G +RLL G+I Sbjct: 28 LNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGII 87 Query: 94 VWSLAQASGGIV-STFGWFIVARIVLGIGEAPQFPSAARVVSNWFPLRARGTPTGIFNAA 152 + G + S F I+AR + G G A VV+ + P RG G+ + Sbjct: 88 INCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSI 147 Query: 153 SPLGTALAPLLLAVLVASFNWRWAFIA---------------------------TGALGL 185 +G + P + ++ +W + + G + + Sbjct: 148 VAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILM 207 Query: 186 VVAVIWFALYRDPAR---------------AQLTAAERAYLDADAQTAVAMPKLTFADWR 230 V +++F L+ + ++D + Sbjct: 208 SVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPF-------MI 260 Query: 231 SLFSHGTTWGMLIGFFGSVYLNWVYLTWLPGYLTMERHMSLIRTGFAASVPFLCGFVGSL 290 + G +G + GF ++ +P + +S G SV G + + Sbjct: 261 GVLCGGIIFGTVAGF----------VSMVPYMMKDVHQLSTAEIG---SVIIFPGTMSVI 307 Query: 291 VAGWLSDVVTRRSRSPVVSRRNAVVVAMLGM----VAFTIPAALVQSNTV--ALACISVV 344 + G++ + +V RR + V +G+ V+F + L+++ + + + V+ Sbjct: 308 IFGYIGGI--------LVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVL 359 Query: 345 IFLANAASACSWALATAAAPPSRIASLGAIQNFGGFIGGALAPILTGVI 393 L+ + S ++++ A + + NF F+ + G + Sbjct: 360 GGLSFTKTVISTIVSSSLKQQEAGAGMSLL-NFTSFLSEGTGIAIVGGL 407
>PF03627#PapG Length = 336 Score = 32.2 bits (73), Expect = 0.002 Identities = 10/20 (50%), Positives = 11/20 (55%) Query: 136 ARLPSDLPLGLYECPAPYRR 155 LP+DLPLG Y PY Sbjct: 158 VALPADLPLGDYSVTIPYTS 177
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 114 bits (287), Expect = 7e-33 Identities = 73/257 (28%), Positives = 125/257 (48%), Gaps = 15/257 (5%) Query: 7 LEGKVALVTGASSGLGQRFAQVLSQAGAKVVLASRRVERLKELRAEIEAAGGAAHVVSLD 66 +EGK+A +TGA+ G+G+ A+ L+ GA + E+L+++ + ++A A D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 67 VTDVQSIKAAIAHAETEAGTIDILVNNSGVSTMQKLVDVTPADFEFVFDTNTRGAFFVAQ 126 V D +I A E E G IDILVN +GV + ++ ++E F N+ G F ++ Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 127 EVAKRMMMRANGNGKPPYRIINIASVAGLRVFPQIGLYAMSKSAVVQMTRAMALEWGRHG 186 V+K MM R +G+ I+ + S + YA SK+A V T+ + LE + Sbjct: 126 SVSKYMMDRRSGS------IVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYN 179 Query: 187 INVNAICPGYIDTEINHYLWETEQGQ---------KLQSMLPRRRVGKPQDLDGLLLLLA 237 I N + PG +T++ LW E G ++ +P +++ KP D+ +L L Sbjct: 180 IRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLV 239 Query: 238 ADESQFINGSIISADDG 254 + ++ I + D G Sbjct: 240 SGQAGHITMHNLCVDGG 256
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 71.0 bits (174), Expect = 1e-14 Identities = 66/280 (23%), Positives = 101/280 (36%), Gaps = 82/280 (29%) Query: 479 VMGHVDHGKTSLLDHIRRAKVAAGEAG------------------GITQHIGAYHVETPR 520 V+ HVD GKT+L + + A E G GIT G + Sbjct: 8 VLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWEN 67 Query: 521 GVITFLDTPGHEAFTAMRARGAKATDIVVLVVAADDGVMPQTKEAIAHAKAGGVPIVVAI 580 + +DTPGH F A R D +L+++A DGV QT+ + G+P + I Sbjct: 68 TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFI 127 Query: 581 NKIDKPEANPDRVKQE----LVAEGVV-----------------PEEYG----------- 608 NKID+ + V Q+ L AE V+ E++ Sbjct: 128 NKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGNDDLLE 187 Query: 609 ----GDSP-----------------FVPV---SAKTGVGIDDLLENVLLQAEVLELKAPI 644 G S PV SAK +GID+L+E + + + Sbjct: 188 KYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVI-----TNKFYSST 242 Query: 645 E---APAKGIVIEAKLDKGKGPVATILVQSGTLNRGDVVL 681 + G V + + + + +A I + SG L+ D V Sbjct: 243 HRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVR 282
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 135 bits (341), Expect = 8e-37 Identities = 87/396 (21%), Positives = 158/396 (39%), Gaps = 16/396 (4%) Query: 27 VFMNVLDTSIANVAIPTISGDLGVSSDQGTWVITSFAVANAISVPLTGWLTDRFGQVRLF 86 F +VL+ + NV++P I+ D WV T+F + +I + G L+D+ G RL Sbjct: 23 SFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLL 82 Query: 87 LASIILFVISSWMCGLAPS-LPFLLASRVLQGAVAGPMIPLSQSLLLSSYPRAKAPMALA 145 L II+ S + + S L+ +R +QGA A L ++ P+ A Sbjct: 83 LFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFG 142 Query: 146 LWSMTTLIAPVAGPILGGWISDNYSWPWIFYVNIPVGIAAALATWSIYRTRESTVRRAPI 205 L + GP +GG I+ W ++ IP+ I + + ++ + Sbjct: 143 LIGSIVAMGEGVGPAIGGMIAHYIHWSYLL--LIPM-ITIITVPFLMKLLKKEVRIKGHF 199 Query: 206 DGVGLALLVLWVGSLQIMLDKGKDLDWFASTTIIALALIAVISFAFFVIWELTAEHPVVD 265 D G+ L+ VG + ML F ++ I+ +++V+SF FV P VD Sbjct: 200 DIKGIILMS--VGIVFFML--------FTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVD 249 Query: 266 LSLFRMRNFTGGTIALAVGYGLYFGNLVLLPLWLQTQIGYTATDAG-LVMAPVGLFAILL 324 L + F G + + +G G + ++P ++ + + G +++ P + I+ Sbjct: 250 PGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIF 309 Query: 325 SPLTGKFLPRTDPRYIATAAFLTFALCFWMRSRYTTGVDEWSLTLPTLVQGIAMAGFFIP 384 + G + R P Y+ ++ F S + + V G ++ Sbjct: 310 GYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLG-GLSFTKTV 368 Query: 385 LVSITLSGLPGHRIPAASGLSNFVRIMCGGIGTSIF 420 + +I S L A L NF + G G +I Sbjct: 369 ISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIV 404
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 71.4 bits (175), Expect = 1e-15 Identities = 44/270 (16%), Positives = 85/270 (31%), Gaps = 28/270 (10%) Query: 94 ADSQVALQQAEANLAQTVRQVRGLFVNDDQYRAQVALRQSDLSKAQDDLRRRVAVAQTGA 153 + Q Q E NL + + + ++Y + +S L L + A+A+ Sbjct: 196 STWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSS-LLHKQAIAKHAV 254 Query: 154 VSQE--------EISHARDAVRAAQASVDAAQQQLASNRALTANTTIASHPNVMAAAAKV 205 + QE E+ + + ++ + +A+++ L N + + Sbjct: 255 LEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLL 314 Query: 206 RD----AYLANARNVLPAPVTGYVAKRSVQ-VGQRVSPGNPLMSVVPLNAV-WVDANFKE 259 +V+ APV+ V + V G V+ LM +VP + V A + Sbjct: 315 TLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQN 374 Query: 260 VQLKHMRIGQPVEL--TADIYGSSAVYHGKVVGFSAGTGSAFSLLPAQNATGNWIKVVQR 317 + + +GQ + A Y GKV + G V+ Sbjct: 375 KDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDA-------IEDQRLGLVFNVIIS 427 Query: 318 LPVRIEIDPKELEKHPLRIGLSMQVDVNIK 347 + + + M V IK Sbjct: 428 IEENCLST----GNKNIPLSSGMAVTAEIK 453 Score = 47.1 bits (112), Expect = 8e-08 Identities = 26/161 (16%), Positives = 54/161 (33%), Gaps = 21/161 (13%) Query: 56 VNGNVVQITPQITGTVIAVKADDTQTVKAGDPLVVLDPADSQVALQQAEANLAQT----- 110 +G +I P V + + ++V+ GD L+ L ++ + +++L Q Sbjct: 92 HSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQT 151 Query: 111 ----------VRQVRGLFVNDDQYRAQVA----LRQSDLSKAQDDLRRRVAVA--QTGAV 154 + ++ L + D+ Y V+ LR + L K Q + Sbjct: 152 RYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDK 211 Query: 155 SQEEISHARDAVRAAQASVDAAQQQLASNRALTANTTIASH 195 + E + + + +L +L IA H Sbjct: 212 KRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKH 252
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 293 bits (752), Expect = 1e-96 Identities = 134/482 (27%), Positives = 202/482 (41%), Gaps = 67/482 (13%) Query: 19 ADIVDRVARCMASFDVEVIRADNAEISPER-AALRPSLAIISVTMIE-TGAAFLRDWQA- 75 A I + + ++ +V NA AA L + V M + L + Sbjct: 13 AAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDLLPRIKKA 72 Query: 76 NIGMPVVWVGA---------ARDHDASQY---PPDYSHILPLDFTCAELRGMIGKLVTQL 123 +PV+ + A A + A Y P D + ++ + + Sbjct: 73 RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP------KRRP 126 Query: 124 RAHAAETLQPSELVAHSESMQALLHEVDTFADCDTNVLLHGETGVGKERIAQLLHQKHSR 183 ++ LV S +MQ + + D +++ GE+G GKE +A+ LH + + Sbjct: 127 SKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHD-YGK 185 Query: 184 YRNGEFVPVNCGAIPDGLFESLFFGHAKGSFTGAVVAHKGYFEQAAGGTLFLDEVGDLPL 243 RNG FV +N AIP L ES FGH KG+FTGA G FEQA GGTLFLDE+GD+P+ Sbjct: 186 RRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPM 245 Query: 244 YQQVKLLRVLEDGAVLRVGATSPIKVDFRLVAASNKKLPQLVKDGLFRADLYYRLAVIEL 303 Q +LLRVL+ G VG +PI+ D R+VAA+NK L Q + GLFR DLYYRL V+ L Sbjct: 246 DAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPL 305 Query: 304 SIPSLEERGAVDKIALFKSFVAEVVGDERLAQLSDLPYWLADAVADS----YFPGNVREL 359 +P L +R D L + FV ++ + + +PGNVREL Sbjct: 306 RLPPLRDRAE-DIPDLVRHFV------QQAEKEGLDVKRFDQEALELMKAHPWPGNVREL 358 Query: 360 RNLAER-----------------------------VGVTVRQTGGWDAARLQRLVAHARN 390 NL R + A + + + + Sbjct: 359 ENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFAS 418 Query: 391 SAQPVPVESAAEVFVDRSKWDMNERSRVIAALDANGWRRQDTALQLGISRKVLWEKMRKY 450 +P + + E ++AAL A + A LG++R L +K+R+ Sbjct: 419 FGDALPPSGLYDRVLAEM-----EYPLILAALTATRGNQIKAADLLGLNRNTLRKKIREL 473 Query: 451 QI 452 + Sbjct: 474 GV 475
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 33.6 bits (77), Expect = 5e-04 Identities = 10/112 (8%), Positives = 31/112 (27%), Gaps = 7/112 (6%) Query: 124 DETRAEAIYRDFSHQAERLAVNELRAAKLESQKAQTDR-------QIALTQERARRLQAD 176 AEA + + + R L + + Sbjct: 128 TALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRL 187 Query: 177 ISIAREQQAAVVDRQKSVRNETAALQAQQAELQSQLRALQQQVRSLQREANA 228 S+ +EQ + +++ +A++ + +++ + R + + Sbjct: 188 TSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDD 239
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 68.5 bits (167), Expect = 5e-16 Identities = 20/82 (24%), Positives = 33/82 (40%) Query: 20 PGNRQAGGTKARILDAAEDLFIEHGFEAMSMRQITSRAAVNLAAVNYHFGSKEALIHAML 79 ++A T+ ILD A LF + G + S+ +I A V A+ +HF K L + Sbjct: 4 KTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIW 63 Query: 80 SRRLDQLNQERLGILDRFDAQL 101 + + L +F Sbjct: 64 ELSESNIGELELEYQAKFPGDP 85
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 68.3 bits (167), Expect = 1e-14 Identities = 74/312 (23%), Positives = 125/312 (40%), Gaps = 15/312 (4%) Query: 11 TIAAYLGWTLDAFDFFLMVFVLKDIAAEFASTIPAVA---FALTLTLAMRPIGALIFGRL 67 I LDA L++ VL + + + A L L M+ A + G L Sbjct: 7 LIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGAL 66 Query: 68 ADRFGRRPTLMVNIACYSLIELASGFAPSLTALLVLRALFGIAMGGEWGVGSALTMETVP 127 +DRFGRRP L+V++A ++ AP L L + R + GI G V A + Sbjct: 67 SDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGIT-GATGAVAGAYIADITD 125 Query: 128 THARGFVSGLLQAGYPSGYLLASVVFGLLYQYIGWRGMFMVGVLPALLVLYVRAHVPES- 186 R G + A + G + V+ GL+ + F L L L +PES Sbjct: 126 GDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESH 185 Query: 187 PAWKQMEKRPRPSLGATLQQNWKLTIYAIVLMTAF--NFFSHGTQDLYPTFLREQHHFDP 244 ++ +R + A+ + +T+ A ++ F L+ F ++ H+D Sbjct: 186 KGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDA 245 Query: 245 HTVSW-ITIVLNLGAIVGGLSFGAISERIGRRRAIFIAALIALPVLPLWAF-SSGPVA-- 300 T+ + L ++ + G ++ R+G RRA+ + + L AF + G +A Sbjct: 246 TTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFP 305 Query: 301 ----LAAGAFLM 308 LA+G M Sbjct: 306 IMVLLASGGIGM 317
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 107 bits (269), Expect = 3e-31 Identities = 45/177 (25%), Positives = 90/177 (50%), Gaps = 3/177 (1%) Query: 1 MARKTREESLAIKHRILDAAELVLLEKGVAQTAMADLAEAAGMSRGAVYGHYRNKMEVCL 60 MARKT++E+ + ILD A + ++GV+ T++ ++A+AAG++RGA+Y H+++K ++ Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 ALCDRAFARTSEGFDAVDSLPA---FATLRRAASHYLQQCGEPGSMQRVLVILYTKCEQS 117 + + + + E + + LR H L+ + ++ I++ KCE Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 118 EENGALQRRRMLLELQMLRITKALLRRAIAAGEIAADLDVHLAAVHLVSLLEGVFAS 174 E +Q+ + L L+ + L+ I A + ADL AA+ + + G+ + Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMEN 177
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 41.4 bits (97), Expect = 5e-06 Identities = 19/132 (14%), Positives = 38/132 (28%), Gaps = 5/132 (3%) Query: 70 VRARVAGIVTARTYEEGQEVKQGAVLFRIDPAPLKAARDAAQGALAKAQAAAL---AASD 126 ++ IV +EG+ V++G VL ++ +A Q +L +A+ S Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSR 158 Query: 127 KRRRYDDLVRDRAVSERDHTEALADDTRAKADVASAKAELAR--AQLQLDYATVTAPIAG 184 + + R + + + Q +L+ A Sbjct: 159 SIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLT 218 Query: 185 RARRALVTEGAL 196 R E Sbjct: 219 VLARINRYENLS 230 Score = 35.2 bits (81), Expect = 4e-04 Identities = 15/101 (14%), Positives = 39/101 (38%), Gaps = 10/101 (9%) Query: 103 LKAARDAAQGALAKAQAAALAASDKRRRYDDLVRDRAVSERDHTEALADDTRAKADVASA 162 + L + ++ L+A ++ + L + E L + ++ Sbjct: 264 AVNELRVYKSQLEQIESEILSAKEEYQLVTQLFK---------NEILDKLRQTTDNIGLL 314 Query: 163 KAELARAQLQLDYATVTAPIAGR-ARRALVTEGALVGQDQA 202 ELA+ + + + + AP++ + + + TEG +V + Sbjct: 315 TLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAET 355
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1079 bits (2792), Expect = 0.0 Identities = 523/1032 (50%), Positives = 714/1032 (69%), Gaps = 6/1032 (0%) Query: 1 MARFFIDRPVFAWVIALFIMLGGAFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEES 60 MA FFI RP+FAWV+A+ +M+ GA AI LPVAQYP IAPP VS+ A YPGA AQ V+++ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTALIEREMNGAPGLLYTSATS-SAGAASLYLTFKQGVNADLAAVEVQNRLKTVEARLPE 119 VT +IE+ MNG L+Y S+TS SAG+ ++ LTF+ G + D+A V+VQN+L+ LP+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 120 PVRRDGIQVEKAADNIQLVVSLTSDDGRMTAVQLGEYASANVVQALRRVDGVGKVQFWGA 179 V++ GI VEK++ + +V SD+ T + +Y ++NV L R++GVG VQ +GA Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 180 EYAMRIWPDPVKLAGHGLTASDIASAVRAHNARVTVGDIGRSAVPDSAPIAATVFADAPL 239 +YAMRIW D L + LT D+ + ++ N ++ G +G + + A++ A Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 240 KTPADFGAIALRTQPDGSALHLRDVARIEFGGNDYNYPSYVNGKVATGMGIKLAPGSNAV 299 K P +FG + LR DGS + L+DVAR+E GG +YN + +NGK A G+GIKLA G+NA+ Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 300 ATEKRVRATMDKLSAYFPPGVKYQIPYETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQ 359 T K ++A + +L +FP G+K PY+T+ FV++S+++VV TL EA +LVFLVM+LF+Q Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 360 NLRATLIPTLVVPVALAGTFGVMYAAGFSINVLTMFGMVLAIGILVDDAIVVVENVERLM 419 N+RATLIPT+ VPV L GTF ++ A G+SIN LTMFGMVLAIG+LVDDAIVVVENVER+M Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 420 VEEGLAPYDATVKAMRQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSLAVSIGF 479 +E+ L P +AT K+M QI GA+VGI +VL++VF+PMAFFGG+ G IYRQF++++ ++ Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 480 SAFLALSLTPALCATLLKPVSGDHHE-KRGFFGWFNGFVARSTQRYATRVGAMLKKPLRW 538 S +AL LTPALCATLLKPVS +HHE K GFFGWFN S Y VG +L R+ Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 Query: 539 LVVYGALTAAAALMLTQLPSAFLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYIRRD 598 L++Y + A ++ +LPS+FLP+EDQG F+ M+ P G T + + +V Y ++ Sbjct: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 Query: 599 EPAAY--TFALGGFNLYGEGPNGGMIFVTLKNWKERKAGRDHVQAIVARINERFAGTANT 656 E A F + GF+ G+ N GM FV+LK W+ER + +A++ R + Sbjct: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG 660 Query: 657 TVFAMNSPALPDLGSTSGFDFRLQNRGGLDYAAFSAAREQLLAVGGKDRA-LTDVMFAGT 715 V N PA+ +LG+ +GFDF L ++ GL + A + AR QLL + + A L V G Sbjct: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 Query: 716 QDAPQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGTQVRRVIVQADGLHRL 775 +D Q KL++D+ KA ALGVS+ +IN T++ G Y+ DF+ +V+++ VQAD R+ Sbjct: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM 780 Query: 776 DPADVQKLRVRNAGGEMVPLAAFATLHWTLGPPQLTRYNGYPSFTINGSAAPGHSSGEAM 835 P DV KL VR+A GEMVP +AF T HW G P+L RYNG PS I G AAPG SSG+AM Sbjct: 781 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM 840 Query: 836 AAIERIAAKLPAGIGHAWSGQSFEERLSGAQAPMLFALSVLVVFLALAALYESWSIPFAV 895 A +E +A+KLPAGIG+ W+G S++ERLSG QAP L A+S +VVFL LAALYESWSIP +V Sbjct: 841 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900 Query: 896 MLVVPLGVIGAVLGVTLRAMPNDIYFKVGLIATIGLSAKNAILIVEVAKDLVAQR-MSLV 954 MLVVPLG++G +L TL ND+YF VGL+ TIGLSAKNAILIVE AKDL+ + +V Sbjct: 901 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV 960 Query: 955 DAALEAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQMAIGTGVLGGMITATVLAVFL 1014 +A L A R+RLRPI+MTSLAF +GVLPLA ++GA SGAQ A+G GV+GGM++AT+LA+F Sbjct: 961 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF 1020 Query: 1015 VPLFFVMVGRLF 1026 VP+FFV++ R F Sbjct: 1021 VPVFFVVIRRCF 1032
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 68.5 bits (167), Expect = 2e-16 Identities = 30/108 (27%), Positives = 56/108 (51%), Gaps = 3/108 (2%) Query: 5 RLTREQSRDQTRERLLKAAHRIFLKKGYVAASVEDIAAAAGYTRGAFYSNFRSKSELLLE 64 R T+++++ +TR+ +L A R+F ++G + S+ +IA AAG TRGA Y +F+ KS+L E Sbjct: 3 RKTKQEAQ-ETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 65 LLERDHDSVRADFEAIFEE--GGPREQMESTALAYYSTLFRDDEYSLL 110 + E ++ + G P + + + ++ LL Sbjct: 62 IWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLL 109
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 43.7 bits (103), Expect = 7e-07 Identities = 27/178 (15%), Positives = 58/178 (32%), Gaps = 11/178 (6%) Query: 86 DVEKNAASAQAQFDAATHSLAFAKQQLERDRAQARENLIATAQL--EQTQNSYTSALAQR 143 + E A + L Q+E + A+E QL + + Sbjct: 256 EQENKYVEAVNELRVYKSQLE----QIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNI 311 Query: 144 DQAQQQLALAKNQLRYATLVADHAGTITAEQADT-GQNVSAGQAVYQLAWSGDVDVV-SD 201 +LA + + + + + A + + + T G V+ + + + D V + Sbjct: 312 GLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTAL 371 Query: 202 VPEAALASLTPGHAASVTLPSLPGREF---AAKVREIAPAADPQSRTYRVKLTLAAPD 256 V + + G A + + + P + KV+ I A R V + + + Sbjct: 372 VQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIE 429 Score = 43.3 bits (102), Expect = 9e-07 Identities = 28/177 (15%), Positives = 60/177 (33%), Gaps = 33/177 (18%) Query: 1 MLLIGTALVLAACHPKEAAPPAPRPVVALPARADGAAVATTLPGEIQPRYATPLSFRIAG 60 M + A +L+ E A G + EI+P I Sbjct: 65 MGFLVIAFILSVLGQVEIVATAN-----------GKLTHSGRSKEIKP---------IEN 104 Query: 61 KIIER-KVRLGDTVKAGQVVALLDPSDVEKNAASAQAQFDAATHSLA---FAKQQLERDR 116 I++ V+ G++V+ G V+ L E + Q+ A + +E ++ Sbjct: 105 SIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNK 164 Query: 117 -------AQARENLIATAQLEQTQNSYTSALA--QRDQAQQQLALAKNQLRYATLVA 164 + ++ ++ + + + Q + Q++L L K + T++A Sbjct: 165 LPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLA 221 Score = 35.6 bits (82), Expect = 3e-04 Identities = 11/71 (15%), Positives = 29/71 (40%) Query: 92 ASAQAQFDAATHSLAFAKQQLERDRAQARENLIATAQLEQTQNSYTSALAQRDQAQQQLA 151 + A+ + + K +L+ + + IA + + +N Y A+ + + QL Sbjct: 217 LTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLE 276 Query: 152 LAKNQLRYATL 162 ++++ A Sbjct: 277 QIESEILSAKE 287 Score = 32.9 bits (75), Expect = 0.002 Identities = 17/126 (13%), Positives = 44/126 (34%), Gaps = 7/126 (5%) Query: 51 ATPLSFRIAGKIIERKVRLGDTVKAGQVVALLDPSDVEKNAASAQAQFDAATHSLAFAKQ 110 ++I + IE + + +V + + + QF + + Sbjct: 148 LEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKEL 207 Query: 111 QLERDRAQ------ARENLIATAQLEQTQNSYTSALAQRDQAQQQLALAKNQLRYATLVA 164 L++ RA+ +++E+++ S+L QA + A+ + + +Y V Sbjct: 208 NLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLH-KQAIAKHAVLEQENKYVEAVN 266 Query: 165 DHAGTI 170 + Sbjct: 267 ELRVYK 272
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 446 bits (1149), Expect = e-142 Identities = 235/1050 (22%), Positives = 433/1050 (41%), Gaps = 65/1050 (6%) Query: 12 LSAWALRHQALVVYLIALATLAGILAYTRLAQSEDPPFTFRVMVIRTFWPGASARQVQEQ 71 ++ + +R L + +AG LA +L ++ P + + +PGA A+ VQ+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 72 VTDRIGRKLQETPAIDFLRSYS-RPGESLIFFTMKDAAPVKDVPETWYQIRKKVGDIGYT 130 VT I + + + ++ S S G I T + D Q++ K+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSG---TDPDIAQVQVQNKLQLATPL 117 Query: 131 LPPGVQGP-FFNDEFGDVYTNIWTLEGDG--FTPAQLHDYAD-QLRTVLLRVPGVGKVDY 186 LP VQ ++ Y + D T + DY ++ L R+ GVG V Sbjct: 118 LPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQL 177 Query: 187 FGDPDQRIFIEADNTQLTRLGISPQQLGQAINAQNDISSAGVLTTADD------RVFVRP 240 FG + I D L + ++P + + QND +AG L + Sbjct: 178 FG-AQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIA 236 Query: 241 SGQFDNVAAIADTLIRIN--GRTFRLGDLATVKRGYDDPVVTQMRANGHAVLGIGVTMQP 298 +F N +R+N G RL D+A V+ G ++ R NG G+G+ + Sbjct: 237 QTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGEN-YNVIARINGKPAAGLGIKLAT 295 Query: 299 GGDVIRLGKALDAESKDLQAQLPAGLKLTLVSSMPHAVAHSVDDFLEAVAEAVAIVLVVS 358 G + + KA+ A+ +LQ P G+K+ V S+ + ++ + EA+ +V +V Sbjct: 296 GANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVM 355 Query: 359 LVSLG-LRTGMVVVISIPVVLAVTALFMYLFDIGLHKVSLGTLVLALGLLVDDAIIAVEM 417 + L +R ++ I++PVVL T + F ++ +++ +VLA+GLLVDDAI+ VE Sbjct: 356 YLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVEN 415 Query: 418 MA-VKLEQGYSRARAAAFAYTSTAFPMLTGTLVTVSGFLPIALAKSSTGEYTRSIFEVSA 476 + V +E A + + ++ +V + F+P+A STG R Sbjct: 416 VERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIV 475 Query: 477 IALIASWFAAVVLIPLLGYHLLPERKKHAHEAHLPDDHEHDIYDTRFYQRLRGW---VDW 533 A+ S A++L P L LL HE ++T F + + V Sbjct: 476 SAMALSVLVALILTPALCATLLKPVSAEHHE---NKGGFFGWFNTTFDHSVNHYTNSVGK 532 Query: 534 CIERRFVVLLITGALFVVALMGFSLVPQQFFPSSDRPELLVDVRLPEGASFTATLRETER 593 + LLI + ++ F +P F P D+ L ++LP GA+ T + ++ Sbjct: 533 ILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQ 592 Query: 594 LEKILDK--RPEIDHSVNFVGSGAPRFYLPLDQQLQLPNFAQFVVTAKSVKDR---EKLA 648 + K + ++ G Q N V+ K ++R E A Sbjct: 593 VTDYYLKNEKANVESVFTVNGFSFSG---------QAQNAGMAFVSLKPWEERNGDENSA 643 Query: 649 TWLETTLRDQFPAVRWRLSRLENGPPV-------GYPVQ-FRVSGDDIATVRSIAEKVAA 700 + + + +R N P + G+ + +G + ++ Sbjct: 644 EAVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLG 703 Query: 701 TMR---GDARTVNVQFDWDEPAERSVRFELDQKKARELNVTSQDVSSFLAMTLSGTTVTQ 757 +V D + E+DQ+KA+ L V+ D++ ++ L GT V Sbjct: 704 MAAQHPASLVSVRPNGLEDTA---QFKLEVDQEKAQALGVSLSDINQTISTALGGTYVND 760 Query: 758 YRERDKLIAVDLRAPRADRVDPAKLAGLALPTPNG-PVPLGSLGRFTPALEYGVVWERDR 816 + +R ++ + ++A R+ P + L + + NG VP + + + Sbjct: 761 FIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNG 820 Query: 817 QPTITVQSDVRAGAQGIDVTHAIDGKLNPLRAQLPVGYQINIGGSVEESAKAQSSINAQM 876 P++ +Q + G D ++ L ++LP G + G + + + A + Sbjct: 821 LPSMEIQGEAAPGTSSGDAMALMEN----LASKLPAGIGYDWTGMSYQERLSGNQAPALV 876 Query: 877 PLMAIAVFTLLMIQLQSFSRVLMVVLTAPLGLIGVVGTLLLFGQPFGFVAMLGVIAMFGI 936 + + VF L +S+S + V+L PLG++GV+ LF Q M+G++ G+ Sbjct: 877 AISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGL 936 Query: 937 IMRNSVILVDQIEQ-DIAAGHGRLDAIVGATVRRFRPITLTAAAAVLALIPLLRSNFFG- 994 +N++++V+ + G G ++A + A R RPI +T+ A +L ++PL SN G Sbjct: 937 SAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGS 996 Query: 995 ----PMATALMGGITSATVLTLFYLPALYA 1020 + +MGG+ SAT+L +F++P + Sbjct: 997 GAQNAVGIGVMGGMVSATLLAIFFVPVFFV 1026 Score = 84.9 bits (210), Expect = 9e-19 Identities = 94/531 (17%), Positives = 184/531 (34%), Gaps = 57/531 (10%) Query: 535 IERRFVVLLITGALFVVALMGFSLVPQQFFPSSDRPELLVDVRLPEGASFTATLRETERL 594 I R ++ L + + +P +P+ P + V P + T T+ + Sbjct: 6 IRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQVI 65 Query: 595 EKILDKRPEIDH--SVNFVGSGAP---RFYLPLDQQLQLPNFAQFVVTAKSVKDREKLAT 649 E+ ++ + + S + F D P+ AQ V K L Sbjct: 66 EQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTD-----PDIAQVQVQNKLQLATPLLP- 119 Query: 650 WLETTLRDQFPAVRWRLSRLENGPPVGYPVQFRVSGDDIATVRSIAEKVAATMRGDARTV 709 V+ + +E V VS + T I++ VA+ ++ + Sbjct: 120 ----------QEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRL 169 Query: 710 N----VQFDWDEPAERSVRFELDQKKARELNVTSQDVSSFL--------AMTLSGTTVTQ 757 N VQ A+ ++R LD + +T DV + L A L GT Sbjct: 170 NGVGDVQLF---GAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALP 226 Query: 758 YRERDKLIAVDLRAPRADRVDPAKLAGLALPTPNG-PVPLGSLGR--FTPALEYGVVWER 814 ++ + I R + L +G V L + R + Sbjct: 227 GQQLNASIIAQTRFKNPEEFGKVTLRV----NSDGSVVRLKDVARVELGGENYNVIARIN 282 Query: 815 DRQPTITVQSDVRAGAQGIDVTHAIDGKLNPLRAQLPVGYQINIGGSVEESAKAQSSINA 874 +P + + GA +D AI KL L+ P G ++ + + Q SI+ Sbjct: 283 G-KPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLY--PYDTTPFVQLSIHE 339 Query: 875 QMPLMAIA---VFTLLMIQLQSFSRVLMVVLTAPLGLIGVVGTLLLFGQPFGFVAMLGVI 931 + + A VF ++ + LQ+ L+ + P+ L+G L FG + M G++ Sbjct: 340 VVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMV 399 Query: 932 AMFGIIMRNSVILVDQIEQDIAAGHGR-LDAIVGATVRRFRPITLTAAAAVLALIPLL-- 988 G+++ +++++V+ +E+ + +A + + + A IP+ Sbjct: 400 LAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFF 459 Query: 989 ---RSNFFGPMATALMGGITSATVLTLFYLPALYAAWFRVKRDERDPHEPP 1036 + + ++ + + ++ L PAL A K + HE Sbjct: 460 GGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLL--KPVSAEHHENK 508
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 334 bits (858), Expect = e-112 Identities = 119/370 (32%), Positives = 182/370 (49%), Gaps = 49/370 (13%) Query: 127 IAYVERLTTVRSASAQPSAEGLVGGADAFNAALGALQRVAPSMLPVLLLGESGTGKELFA 186 +A +R + +Q LVG + A L R+ + L +++ GESGTGKEL A Sbjct: 119 LAEPKRRPSKLEDDSQDGM-PLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVA 177 Query: 187 RALHEASARAMGPFVVVDCSGIAETLFESELFGYEKGAFTGANQRKPGLVETAQGGTLFL 246 RALH+ R GPFV ++ + I L ESELFG+EKGAFTGA R G E A+GGTLFL Sbjct: 178 RALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFL 237 Query: 247 DEIGDVPLPMQVKLLRLIESGTFRRVGGVEALRADFRLVAATHKPLREMIDDGRFRQDLY 306 DEIGD+P+ Q +LLR+++ G + VGG +R+D R+VAAT+K L++ I+ G FR+DLY Sbjct: 238 DEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLY 297 Query: 307 YRINAFPIPLPALRERQGDVALLAESILRRIANARGNAGDASARPFAARPFVLTERARAC 366 YR+N P+ LP LR+R D+ L +++ + A Sbjct: 298 YRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGL------------DVKRFDQEALEL 345 Query: 367 LDAYAWPGNIRELRNVLERACLFADDGTIRVEHLP----AELVAAAAAPHERDADARGLS 422 + A+ WPGN+REL N++ R I E + +E+ + + + +S Sbjct: 346 MKAHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSIS 405 Query: 423 DAE--------------------------------LVRIARTFDGTRKALAEHVGMSERT 450 A ++ G + A+ +G++ T Sbjct: 406 QAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNT 465 Query: 451 LYRRMKALGL 460 L ++++ LG+ Sbjct: 466 LRKKIRELGV 475
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 38.7 bits (90), Expect = 9e-05 Identities = 46/247 (18%), Positives = 79/247 (31%), Gaps = 49/247 (19%) Query: 576 VVGQDEAISAVADAIRRSRAGLADPNRPYGSFLFLGPTGVGKTELCKALASFLFDSEEHL 635 +VG+ A+ + + R L + + G +G GK + +AL + Sbjct: 139 LVGRSAAMQEIYRVLAR----LMQTDLT---LMITGESGTGKELVARALHDYGKRRNGPF 191 Query: 636 IRIDMSEFMEKHSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSV-------ILLDEIEKA 688 + I+M+ + L G+E+G + T A R + LDEI Sbjct: 192 VAINMAAIPRDLIESEL-------FGHEKGAF-TGAQTRSTGRFEQAEGGTLFLDEIGDM 243 Query: 689 HPDVFNVLLQVLDDG---RMTDGQGRTVDFKNTVIVMTSNLGSQVIQAMTGAPQEEIKDA 745 D LL+VL G + D + ++ A ++ I Sbjct: 244 PMDAQTRLLRVLQQGEYTTVGGRTPIRSDVR-------------IVAATNKDLKQSINQ- 289 Query: 746 VWIEVKQHFRPEFLNRIDDVVVFHALDRSNIESIAKIQLAR-LHDRLAKLDM-ALDVSPA 803 FR + R++ V + R E I L R + K + Sbjct: 290 ------GLFREDLYYRLNVVPLRLPPLRDRAEDIP--DLVRHFVQQAEKEGLDVKRFDQE 341 Query: 804 ALEQIAK 810 ALE + Sbjct: 342 ALELMKA 348 Score = 32.9 bits (75), Expect = 0.005 Identities = 33/169 (19%), Positives = 59/169 (34%), Gaps = 31/169 (18%) Query: 135 SLEAAIAAVRGGSQ-------VHSQDAESQREALKKYTVDLTERARAG-KLDPVIGRDDE 186 + AI A G+ ++ AL + ++ P++GR Sbjct: 86 TFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAA 145 Query: 187 IRRSIQILQRRTKNN-PVLI-GEPGVGKTAIVEGLAQR----------IVNGEVPETLKG 234 ++ ++L R + + ++I GE G GK + L I +P L Sbjct: 146 MQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDL-- 203 Query: 235 KRVLSLDMAALLAGAKYRGEFEERLKAVLNDIAKDEGQTIVFIDEIHTM 283 + + L G + +G F + EG T+ F+DEI M Sbjct: 204 -------IESELFGHE-KGAFTGAQTRSTGRFEQAEGGTL-FLDEIGDM 243
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 31.4 bits (71), Expect = 0.002 Identities = 15/74 (20%), Positives = 26/74 (35%), Gaps = 8/74 (10%) Query: 57 HLPKMVSFWSSLVLGTKGYRGNVQQAHQPLDGIEPAHFSRWLSLFLKTVEGRYTPPAAIR 116 + K S+V +G P G AH+ W L L + T P ++ Sbjct: 136 NRGKAFGLIGSIVAMGEGV--------GPAIGGMIAHYIHWSYLLLIPMITIITVPFLMK 187 Query: 117 FMEPALRIAQSLQL 130 ++ +RI + Sbjct: 188 LLKKEVRIKGHFDI 201
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 33.2 bits (76), Expect = 0.001 Identities = 32/140 (22%), Positives = 54/140 (38%), Gaps = 13/140 (9%) Query: 134 YVVDQNTGEPLFDKNSHAVVPIASISKLMTAMVVLDAKSPMTDQL----EVTDED-RDYE 188 +D +G L + P+ S K++ VL +QL +D DY Sbjct: 43 IEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYS 102 Query: 189 KGTGSRLSVGSVLSREDMLHIALMASENRAAAALSRYYPGGRPAFIAAMNAKAKSLGMND 248 + L+ G ++ ++ A+ S+N AA L G A + A + +G N Sbjct: 103 PVSEKHLADG--MTVGELCAAAITMSDNSAANLLLATVGG-----PAGLTAFLRQIGDNV 155 Query: 249 THFE-NSTGLSSSNVSSARD 267 T + T L+ + ARD Sbjct: 156 TRLDRWETELNEALPGDARD 175
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 33.7 bits (76), Expect = 0.002 Identities = 20/84 (23%), Positives = 32/84 (38%), Gaps = 3/84 (3%) Query: 26 PGDVIEKEQTLITLESDKASMEV--PSDVAGT-VKEVKVKAGEKVSQGTVIAIVEAAAGD 82 P V+ E+ + + + P D GT + + E S+ VI+ Sbjct: 151 PSTVLPTEKPTLFTKLTSEQLTTAQPDDAPGTPAQPLTPLVAEAQSKAEVISTPSPVTAA 210 Query: 83 AAPAKAPEAAKPAPAAPAPAAAAP 106 A+P P +P P AP +AP Sbjct: 211 ASPLITPHQTQPLPTVAAPVLSAP 234
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 36.0 bits (83), Expect = 4e-04 Identities = 23/127 (18%), Positives = 45/127 (35%), Gaps = 15/127 (11%) Query: 161 VPSPAAGVVKEIKVKVGDSVSEGTLIVLLDAAGAPA---------------AAAPQASAP 205 + +VKEI VK G+SV +G +++ L A GA A Q + Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSR 158 Query: 206 APAAPAPAAAPAPAQAAPAPAAAAPAAAPSGEYRASHASPSVRKFARELGVEVARVQGSG 265 + P + + + + ++ +K+ +EL ++ R + Sbjct: 159 SIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLT 218 Query: 266 PKGRITK 272 RI + Sbjct: 219 VLARINR 225 Score = 32.1 bits (73), Expect = 0.006 Identities = 13/38 (34%), Positives = 20/38 (52%), Gaps = 1/38 (2%) Query: 49 VPSPAGGTVKEVKVKVGDSVSEGSLIILLEG-GAAAQV 85 + VKE+ VK G+SV +G +++ L GA A Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADT 136
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 112 bits (282), Expect = 3e-31 Identities = 39/153 (25%), Positives = 67/153 (43%), Gaps = 4/153 (2%) Query: 11 TVFVVDDDEAVRDSLRWLLEANGYRVQCFSSAEQFLDAYQPAQQAGQIACLILDVRMSGM 70 T+ V DDD A+R L L GY V+ S+A AG ++ DV M Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIA----AGDGDLVVTDVVMPDE 60 Query: 71 SGLELQERLIADNAALPIIFVTGHGDVPMAVSTMKKGAMDFIEKPFDEAELRKLVERMLD 130 + +L R+ LP++ ++ A+ +KGA D++ KPFD EL ++ R L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 131 KARSESKSVQEQRAASERLSKLTAREQQVLERI 163 + + +++ L +A Q++ + Sbjct: 121 EPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVL 153
>PF05272#Virulence-associated E family protein Length = 892 Score = 32.0 bits (72), Expect = 0.005 Identities = 17/75 (22%), Positives = 23/75 (30%), Gaps = 25/75 (33%) Query: 305 LHAAWVQELGEMRDRIRAMRNGLVERLKASGVDRDFSFINAQRGMFSYSGLTSAQVDRLR 364 + EL EM A R E +K +F S++ DR R Sbjct: 639 IAGIVAYELSEMT----AFRRADAEAVK--------AFF-------------SSRKDRYR 673 Query: 365 EEFGIYAVGTGRICV 379 +G Y R V Sbjct: 674 GAYGRYVQDHPRQVV 688
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 104 bits (261), Expect = 5e-29 Identities = 74/261 (28%), Positives = 121/261 (46%), Gaps = 11/261 (4%) Query: 2 AADLSGKTAVVTGAASGIGKEIALELAKAGAAVAIADLNQDGANAVADEINKAGGKAIGV 61 A + GK A +TGAA GIG+ +A LA GA +A D N + V + A Sbjct: 3 AKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAF 62 Query: 62 AMDVTNEDAVNNGIDKVAEAFGSVDILVSNAGIQIVNPIENYSFSDWKKMQAIHVDGAFL 121 DV + A++ ++ G +DILV+ AG+ I + S +W+ +++ G F Sbjct: 63 PADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 122 TTKAALKHMYKDDRGGVVIYMGSVHSHEASPLKSAYVTAKHGLLGLARVLAKEGAKHNVR 181 +++ K+M D R G ++ +GS + +AY ++K + + L E A++N+R Sbjct: 123 ASRSVSKYM-MDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIR 181 Query: 182 SHVVCPGFVRTPLVDKQIPEQAKELGISEEEVIK----KVMLGNTVDGVFTTVQDVAQTV 237 ++V PG T D Q A E G E+VIK G + D+A V Sbjct: 182 CNIVSPGSTET---DMQWSLWADENG--AEQVIKGSLETFKTGIPL-KKLAKPSDIADAV 235 Query: 238 LFLSAFPSAALTGQSVVVSHG 258 LFL + + +T ++ V G Sbjct: 236 LFLVSGQAGHITMHNLCVDGG 256
>PF06872#EspG protein Length = 398 Score = 30.1 bits (67), Expect = 0.010 Identities = 17/61 (27%), Positives = 31/61 (50%), Gaps = 6/61 (9%) Query: 160 ALVLIDPSYEDKKDYART---VTCVTECLKRFATGCYAIWYPQVARVESQRFPEQLKRLQ 216 A +++D + + DY + +TC + LK G +W P+ ++ E Q+F L L+ Sbjct: 27 ASLVLDATIKINSDYKKPWNEMTCAEKLLKILTLG---LWNPKYSQDERQQFQGLLTVLE 83 Query: 217 P 217 P Sbjct: 84 P 84
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 26.6 bits (58), Expect = 0.027 Identities = 17/49 (34%), Positives = 23/49 (46%), Gaps = 2/49 (4%) Query: 50 GGLVLQTAPLSSEPIVEPAGMRMPAGQGPNSSVPLFVAPYINVPGWGAS 98 G +V A S EP+V G+ +G+ P F AP + V GAS Sbjct: 274 GNVVFDRA--SGEPVVIDLGLHSRSGEQPKGFTESFKAPELGVGNLGAS 320
>cloacin#Cloacin signature. Length = 551 Score = 33.9 bits (77), Expect = 0.001 Identities = 23/70 (32%), Positives = 32/70 (45%), Gaps = 4/70 (5%) Query: 20 SGSLSKGTGGSGSGSGDTTASTGGTAN----GTSGTSASNGGTGGAGSTDGTGNGASGTS 75 SG+++ G G G G G + S + N G SG+ GG G G+ G GN G+ Sbjct: 17 SGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSG 76 Query: 76 ANGVGQTLAA 85 G +AA Sbjct: 77 TGGNLSAVAA 86
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 33.0 bits (75), Expect = 0.001 Identities = 15/71 (21%), Positives = 21/71 (29%) Query: 34 LLPTQNPPAPISEALIEPVGETAGEPLTMPPVPAPTHPEEPEAPKKPHREVPRPKPVQRA 93 L P E ++EP E P P +P+ KP + +R Sbjct: 54 DLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRD 113 Query: 94 EPPAPPPPPPP 104 P P P Sbjct: 114 VKPVESRPASP 124 Score = 32.3 bits (73), Expect = 0.002 Identities = 20/67 (29%), Positives = 25/67 (37%), Gaps = 1/67 (1%) Query: 41 PAPISEALIEPVGETAGEPLTMPPVPAPTHPEEPEAPKKPHREVPRPKPVQRAEPPAPPP 100 PAP + V EP P EPE +P E P+ PV +P P Sbjct: 39 PAPAQPISVTMVTPADLEPPQAVQPPPEP-VVEPEPEPEPIPEPPKEAPVVIEKPKPKPK 97 Query: 101 PPPPPLV 107 P P P+ Sbjct: 98 PKPKPVK 104
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 56.0 bits (135), Expect = 1e-10 Identities = 38/144 (26%), Positives = 58/144 (40%), Gaps = 6/144 (4%) Query: 255 VIAACIIVPQAIVAMLSPWVGRSSQRWGRRPILLLGFSALPVRALLFAGVSSPYLLVPVQ 314 ++ A + Q A P +G S R+GRRP+LL+ + V + A ++L + Sbjct: 47 ILLALYALMQFACA---PVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGR 103 Query: 315 MLDGISAAVFGVMLPLIAADVAGGKGRYNLCIGLFGLAAGIGATLSTAVAGYVADHFGNT 374 ++ GI+ A V I AD+ G R G G G + G + F Sbjct: 104 IVAGITGATGAVAGAYI-ADITDGDERARH-FGFMSACFGFGMVAGPVLGGLMGG-FSPH 160 Query: 375 TSFFGLAAAGALAALLVWLAMPET 398 FF AA L L +PE+ Sbjct: 161 APFFAAAALNGLNFLTGCFLLPES 184
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 30.2 bits (68), Expect = 0.031 Identities = 13/36 (36%), Positives = 19/36 (52%), Gaps = 1/36 (2%) Query: 151 GVMVTLVRDSLTVMFLLGYLFYLNWRLTLIVAVILP 186 V+ TL + V ++ YLF N R TLI + +P Sbjct: 339 EVVKTLFEAIMLVFLVM-YLFLQNMRATLIPTIAVP 373
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 111 bits (278), Expect = 1e-28 Identities = 76/398 (19%), Positives = 159/398 (39%), Gaps = 16/398 (4%) Query: 25 LAVLDGAIANVALPTIARDLHASDAASIWIVNAYQLAVTITLLPLASLGERVGYRRIYIA 84 +VL+ + NV+LP IA D + A++ W+ A+ L +I L +++G +R+ + Sbjct: 25 FSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLF 84 Query: 85 GLALFTAASLGCALAGS-LPMLAVMRVIQGFGAAGIMSVNAALVRMIYPSSMLGRGLSIN 143 G+ + S+ + S +L + R IQG GAA ++ +V P G+ + Sbjct: 85 GIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLI 144 Query: 144 AMVVALSSAIGPTVASAILSFASWPWLFAVNVPIGIAAVLGSVRALPANPLHDAPYDFAS 203 +VA+ +GP + I + W +L + + I I V ++ L +D Sbjct: 145 GSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPM-ITIITVPFLMKLLKKEVRIKGHFDIKG 203 Query: 204 ALM--NACVFGLLITAVDGLGHGERHAYVAAELAVAFVVGYFFVKRQLSQPAPLLPVDLM 261 ++ VF +L T + L V+ + FVK P + L Sbjct: 204 IILMSVGIVFFMLFTTSYSISF----------LIVSVLSFLIFVKHIRKVTDPFVDPGLG 253 Query: 262 RIPMFALSIYTSMASFTSQMLAFVALPFWLQNSLGFSQVETG-LYMTPWPLVIVFAAPLA 320 + F + + F + +P+ +++ S E G + + P + ++ + Sbjct: 254 KNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIG 313 Query: 321 GVLSDRYSAGILGGIGLALFAAGLLSLATIGAHPGTVDIVWRMALCGAGFGLFQSPNNRA 380 G+L DR + IG+ + L+ + + + + + G ++ + Sbjct: 314 GILVDRRGPLYVLNIGVTFLSVSFLTASFL-LETTSWFMTIIIVFVLGGLSFTKTVISTI 372 Query: 381 MLSSAPRERSGGAGGMLSTARLTGQTLGAALVALIFGL 418 + SS ++ +G +L+ + G A+V + + Sbjct: 373 VSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSI 410
>TYPE3IMPPROT#Type III secretion system inner membrane P protein family signature. Length = 224 Score = 30.5 bits (69), Expect = 0.010 Identities = 18/77 (23%), Positives = 33/77 (42%), Gaps = 3/77 (3%) Query: 92 YRSDLTRFDRQEYAGYLRVNAM---LAKQLAALLRPDDLIWVHDYHLLPFAHCLRELGVK 148 YR L ++ +E + + ++ + R D I L A+ L E+ Sbjct: 99 YRDYLIKYSDRELVQFFENAQLKRQYGEETETVKRDKDEIEKPSIFALLPAYALSEIKSA 158 Query: 149 NPIGFFLHIPFPSPDML 165 IGF+L++PF D++ Sbjct: 159 FKIGFYLYLPFVVVDLV 175
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.015 Identities = 14/35 (40%), Positives = 17/35 (48%) Query: 32 VVFVGPSGCGKSTLMRMIAGLEDISSGELLIDGAK 66 VV G G GKSTL+ + GL+ S I K Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGK 633
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 29.4 bits (66), Expect = 0.012 Identities = 16/55 (29%), Positives = 23/55 (41%), Gaps = 2/55 (3%) Query: 62 RVLAGASEAVGRTLSADDV-DAIRRAVEAAAV-NAPVVDGIEAALAEISLTTACA 114 RV+ G L DDV AI +E A + N ++GI+A + A Sbjct: 90 RVVHGGEYFTSSVLITDDVLKAITDCIELAPLHNPANIEGIKACTQIMPDVPMVA 144
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 34.3 bits (78), Expect = 0.001 Identities = 98/445 (22%), Positives = 165/445 (37%), Gaps = 77/445 (17%) Query: 6 LDAAARCFAGAALATAACAASA------GTLTIATLNNPDMIELKKLSPAFEKANPDIKL 59 + AR A +AL T +ASA G L I + L ++ FEK D + Sbjct: 3 IKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEK---DTGI 59 Query: 60 NWVILEENVLRQRATTDITTGSGQFDVMAIGTYETPQWGKRGWLAPMTGLPADYDLNDIV 119 + + L ++ TG G D++ + + G LA +T P + + Sbjct: 60 KVTVEHPDKLEEKFPQVAATGDGP-DIIFWAHDRFGGYAQSGLLAEIT--PDKAFQDKLY 116 Query: 120 KTARDSLSYNGQLYALPFYVESSMTFYRKDLFAAKGLKMPDQP-TYDQIAEFADKLTDKA 178 D++ YNG+L A P VE+ Y KDL +P+ P T+++I +L KA Sbjct: 117 PFTWDAVRYNGKLIAYPIAVEALSLIYNKDL-------LPNPPKTWEEIPALDKEL--KA 167 Query: 179 KGTYGICLRGKAGWGENMAYVSTVVNTFGGRWFD-ENW-----NAQLTSPEWKKAIGFYV 232 KG + + + + ++ GG F EN + + + K + F V Sbjct: 168 KGKSALMFNLQEPY-----FTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLV 222 Query: 233 NLLKK-----DGPPGASSNGFNENLTLTASGKCAMWIDATVAAGMLYNKQQSQVADKIGF 287 +L+K D + FN+ G+ AM I+ A N S+V G Sbjct: 223 DLIKNKHMNADTDYSIAEAAFNK-------GETAMTINGPWAWS---NIDTSKV--NYGV 270 Query: 288 AAAPVAATPKGSHWLWAWALAVPKTSKQQDAARKFIA-WATSKQYIEMAGKDEGWASVPP 346 P ++ + + S ++ A++F+ + + + +E KD+ Sbjct: 271 TVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDK------- 323 Query: 347 GTRTSTYQRPEYKAAAPFSDFVLKAIETADPNDPSLKKV---PYTGVQYVGIPEFQSFGT 403 P LK+ E DP + G IP+ +F Sbjct: 324 ----------------PLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWY 367 Query: 404 VVGQAIAGAVAGQTTVDQALAAGQA 428 V A+ A +G+ TVD+AL Q Sbjct: 368 AVRTAVINAASGRQTVDEALKDAQT 392
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 129 bits (324), Expect = 2e-38 Identities = 81/259 (31%), Positives = 124/259 (47%), Gaps = 15/259 (5%) Query: 3 LEQKVAILTGAASGIGEAVAQRYLDEGARCVLVDVKPASGSLARLIEASPGR-AVAVTAD 61 +E K+A +TGAA GIGEAVA+ +GA VD P + R A A AD Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 62 VTRRDDIERIVATAVERFGGVDILFNNAALFDMRPLLDESWDVFDRLFAVNVKGLFFLMQ 121 V I+ I A G +DIL N A + + S + ++ F+VN G+F + Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 122 AVAQRMVEQGRGGKIVNMSSQAGRRGEALVSHYCATKAAVISYTQSAALALAPHRINVNG 181 +V++ M+++ R G IV + S ++ Y ++KAA + +T+ L LA + I N Sbjct: 126 SVSKYMMDR-RSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184 Query: 182 IAPGVVDTPMWEQVDALFARYEHRPPGEKKRLVGEA------VPLGRMGVPGDLTGAALF 235 ++PG +T M + A G ++ + G +PL ++ P D+ A LF Sbjct: 185 VSPGSTETDMQWSLWA-------DENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLF 237 Query: 236 LASADADYITAQTLNVDGG 254 L S A +IT L VDGG Sbjct: 238 LVSGQAGHITMHNLCVDGG 256
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 131 bits (331), Expect = 2e-38 Identities = 77/312 (24%), Positives = 129/312 (41%), Gaps = 39/312 (12%) Query: 18 LLAASAAVLSIAVPAF-----AQAATVNVVAAENFYGDVASQIGGRHVAVTSILSNPDQD 72 LL + + + A + VVA + D+ I G + + SI+ QD Sbjct: 7 LLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIADITKNIAGDKIDLHSIVP-IGQD 65 Query: 73 PHLFEASPKTARALQHAQVVIYNGAN----YDPWMSKLLGASKQAKRA-TIVVADLVGK- 126 PH +E P+ + A ++ YNG N + W +KL+ +K+ + V+D V Sbjct: 66 PHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTKLVENAKKTENKDYFAVSDGVDVI 125 Query: 127 -------KAGDNPHVWYDPATMPAAARAIAAELGRADPANKADYDANLQKFVASL----K 175 K ++PH W + A+ IA +L DP NK Y+ NL+++ L K Sbjct: 126 YLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSAKDPNNKEFYEKNLKEYTDKLDKLDK 185 Query: 176 PVDDKVAALRAQYKGVPVTATEPVFGYMSDAIGLDMRNQRFQLATMNDTEASAQDVAAFE 235 DK + A+ K + VT +E F Y S A G+ + + E + + + Sbjct: 186 ESKDKFNKIPAEKKLI-VT-SEGAFKYFSKAYGV---PSAYIWEINTEEEGTPEQIKTLV 240 Query: 236 NDLRKKQVRVLIYNSQA-EAPMTKRLLKVARDGGVP------SVSVTETQPAGKTFQQWM 288 LR+ +V L S + PM V++D +P + S+ E G ++ M Sbjct: 241 EKLRQTKVPSLFVESSVDDRPMK----TVSQDTNIPIYAQIFTDSIAEQGKEGDSYYSMM 296 Query: 289 TGQLDALAAALS 300 LD +A L+ Sbjct: 297 KYNLDKIAEGLA 308
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.013 Identities = 19/70 (27%), Positives = 33/70 (47%), Gaps = 4/70 (5%) Query: 2 SPTPHALALDRVTLELGGRTILRDVSFSIEPG---EFVGVL-GPNGAGKTTLMRAVLGLV 57 +P + R +G ++ V+ +EPG ++ VL G G GK+TL+ ++GL Sbjct: 561 TPDDYKPRRLRYLQLVGKYILMGHVARVMEPGCKFDYSVVLEGTGGIGKSTLINTLVGLD 620 Query: 58 PVSGGTLSVG 67 S +G Sbjct: 621 FFSDTHFDIG 630
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1267 bits (3281), Expect = 0.0 Identities = 676/1035 (65%), Positives = 823/1035 (79%), Gaps = 2/1035 (0%) Query: 1 MAKFFIDRPIFAWVIAIILMLAGVAAIFTLPISQYPTIAPPSIQITANYPGASAKTVEDT 60 MA FFI RPIFAWV+AIILM+AG AI LP++QYPTIAPP++ ++ANYPGA A+TV+DT Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQVIEQQMSGLDNFLYMSSTSDDSGNATITLTFAPGTNADIAQVQVQNKLSLATPVLPQ 120 VTQVIEQ M+G+DN +YMSSTSD +G+ TITLTF GT+ DIAQVQVQNKL LATP+LPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 VVQQLGLSVTKSSSSFLLVLAFNSEDGSMNKYDLANFVASHVKDPISRLNGVGTVTLFGS 180 VQQ G+SV KSSSS+L+V F S++ + D++++VAS+VKD +SRLNGVG V LFG+ Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QYAMRIWLDPTRLTNYGLTPVDVSSAIAAQNVQIAGGQIGGTPAKPGTVLQATITESTLL 240 QYAMRIWLD L Y LTPVDV + + QN QIA GQ+GGTPA PG L A+I T Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 QTPEQFGNILLKVNQDGSQVRLKDVSKIELGGENYNFDTKYNGQPTAALGIQLATNANAL 300 + PE+FG + L+VN DGS VRLKDV+++ELGGENYN + NG+P A LGI+LAT ANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 ATAKAVRAKIDELAPFFPHGLVVKYPYDTTPFVKLSIEEVVKTLLEGIVLVFLVMYLFLQ 360 TAKA++AK+ EL PFFP G+ V YPYDTTPFV+LSI EVVKTL E I+LVFLVMYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NLRATIIPTIAVPVVLLGTFAIMSMVGFSINTLSMFGLVLAIGLLVDDAIVVVENVERVM 420 N+RAT+IPTIAVPVVLLGTFAI++ G+SINTL+MFG+VLAIGLLVDDAIVVVENVERVM Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 AEEGLSPKEATRKAMGQITGALVGVALVLSAVFVPVAFSGGSVGAIYRQFSLTIVSAMVL 480 E+ L PKEAT K+M QI GALVG+A+VLSAVF+P+AF GGS GAIYRQFS+TIVSAM L Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLVALILTPALCATILKPIPQGHHEEKKGFFGWFNRTFNNSREKYHVGVHHVIKRSGRW 540 SVLVALILTPALCAT+LKP+ HHE K GFFGWFN TF++S Y V ++ +GR+ Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 Query: 541 LIIYLVVIVAVGLLFVRLPKSFLPDEDQGLMFVIVQTPSGSTQETTARTLANISDYLLKD 600 L+IY +++ + +LF+RLP SFLP+EDQG+ ++Q P+G+TQE T + L ++DY LK+ Sbjct: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 Query: 601 EKEIVESAFTVNGFSFAGRGQNSGLVFVRLKDYSQRQHANQKVQALIGRMFGRYAGYKDA 660 EK VES FTVNGFSF+G+ QN+G+ FV LK + +R +A+I R +D Sbjct: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG 660 Query: 661 MVIPFNPPSIPELGTAAGFDFELTDNAGLGHNALMAARNQLLGMAAKDP-TLQGVRPNGL 719 VIPFN P+I ELGTA GFDFEL D AGLGH+AL ARNQLLGMAA+ P +L VRPNGL Sbjct: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 Query: 720 NDTPQYKVDIDREKANALGVTAEAIDQTFSIAWASKYVNNFLDTDGRIKKVYVQSDAPFR 779 DT Q+K+++D+EKA ALGV+ I+QT S A YVN+F+D GR+KK+YVQ+DA FR Sbjct: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFID-RGRVKKLYVQADAKFR 779 Query: 780 MTPEDLNVWYVRNGSGGMVPFGAFATGHWTYGSPKLERYNGVSAMEIQGQAAPGKSTGQA 839 M PED++ YVR+ +G MVPF AF T HW YGSP+LERYNG+ +MEIQG+AAPG S+G A Sbjct: 780 MLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDA 839 Query: 840 MTAMEGLAKKLPVGIGYSWTGLSFQEIQSGSQAPILYAISILVVFLCLAALYESWSIPFS 899 M ME LA KLP GIGY WTG+S+QE SG+QAP L AIS +VVFLCLAALYESWSIP S Sbjct: 840 MALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVS 899 Query: 900 VIMVVPLGVVGALLAATMRGLENDVFFQVGLLTTVGLSAKNAILIVEFARELQMTEKMGP 959 V++VVPLG+VG LLAAT+ +NDV+F VGLLTT+GLSAKNAILIVEFA++L E G Sbjct: 900 VMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGV 959 Query: 960 IEAALEAARLRLRPILMTSLAFILGVMPLAISNGAGSASQHAIGTGVIGGMITATFLAIF 1019 +EA L A R+RLRPILMTSLAFILGV+PLAISNGAGS +Q+A+G GV+GGM++AT LAIF Sbjct: 960 VEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIF 1019 Query: 1020 MIPMFFVKIRAIFSG 1034 +P+FFV IR F G Sbjct: 1020 FVPVFFVVIRRCFKG 1034 Score = 71.8 bits (176), Expect = 1e-14 Identities = 53/324 (16%), Positives = 113/324 (34%), Gaps = 15/324 (4%) Query: 724 QYKVDIDREKANALGVTAEAIDQTFS---IAWASKYVNNFLDTDGRIKKVYVQSDAPFRM 780 ++ +D + N +T + A+ + G+ + + F+ Sbjct: 183 AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK- 241 Query: 781 TPEDLNVWYVR-NGSGGMVPFGAFATGHWTYGSPKLE---RYNGVSAMEIQGQAAPGKST 836 PE+ +R N G +V A G R NG A + + A G + Sbjct: 242 NPEEFGKVTLRVNSDGSVVRLKDVARV--ELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 837 ----GQAMTAMEGLAKKLPVGIGYSWTGLSFQEIQSGSQAPILYAI-SILVVFLCLAALY 891 + L P G+ + + +Q + +I++VFL + Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 892 ESWSIPFSVIMVVPLGVVGALLAATMRGLENDVFFQVGLLTTVGLSAKNAILIVEFAREL 951 ++ + VP+ ++G G + G++ +GL +AI++VE + Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 952 QMTEKMGPIEAALEAARLRLRPILMTSLAFILGVMPLAISNGAGSASQHAIGTGVIGGMI 1011 M +K+ P EA ++ ++ ++ +P+A G+ A ++ M Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 1012 TATFLAIFMIPMFFVKIRAIFSGE 1035 + +A+ + P + S E Sbjct: 480 LSVLVALILTPALCATLLKPVSAE 503
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 42.9 bits (101), Expect = 2e-06 Identities = 40/215 (18%), Positives = 69/215 (32%), Gaps = 34/215 (15%) Query: 100 AQLNSAKATLAKAQANLVTQNALVARYKVLVAANAVSKQEYDNAVATQ-GQAAADVAAGK 158 + A L ++ L + + K + Q + N + + Q ++ Sbjct: 259 NKYVEAVNELRVYKSQLEQIESEILSAK---EEYQLVTQLFKNEILDKLRQTTDNIGLLT 315 Query: 159 AAVDTAQINLGYTDVVSPISGRV-GISQVTPGAYVQASQATLMSTVQQLDPVYVDLTQSS 217 + + + + +P+S +V + T G V ++ TLM V + D + V + Sbjct: 316 LELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAE-TLMVIVPEDDTLEVTALVQN 374 Query: 218 LD------GLKLRQDVQSGRLKTSGPGAAKVSLILEDGKTYSDAGKLQFSDVTVDQTTGS 271 D G V++ G KV I D DQ G Sbjct: 375 KDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNI--------------NLDAIEDQRLGL 420 Query: 272 VT--IRAV------FPNPGRVLLPGMFVRARIEEG 298 V I ++ N L GM V A I+ G Sbjct: 421 VFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTG 455 Score = 29.4 bits (66), Expect = 0.027 Identities = 12/34 (35%), Positives = 17/34 (50%), Gaps = 1/34 (2%) Query: 63 AQVRARVDGIVLR-REFTEGGDVKAGQRLYKIDP 95 + +RA V V + + TEGG V + L I P Sbjct: 328 SVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVP 361
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 117 bits (294), Expect = 6e-35 Identities = 78/208 (37%), Positives = 115/208 (55%) Query: 1 MVRRTKEEALETRNRILDAAEHVFFEKGVSHTSLADIAQHAGVTRGAIYWHFANKSELFD 60 M R+TK+EA ETR ILD A +F ++GVS TSL +IA+ AGVTRGAIYWHF +KS+LF Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 AMFDRVFLPIDELKRMPHDAPGGNPLDTIRKILIWCLLGVQRDSQLRRVFSILFMKCEYV 120 +++ I EL+ G+PL +R+ILI L + + R + I+F KCE+V Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 121 ADMEPLLQRNRAGMSEALHAIDADLAVAVRLKLLPERLDTWRATLMLHTLVSGFVRDMLM 180 +M + Q R E+ I+ L + K+LP L T RA +++ +SG + + L Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180 Query: 181 LPDEIDAEEHAEKLVDGCFDMLRYSPAM 208 P D ++ A V +M P + Sbjct: 181 APQSFDLKKEARDYVAILLEMYLLCPTL 208
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 43.1 bits (101), Expect = 4e-07 Identities = 26/128 (20%), Positives = 45/128 (35%), Gaps = 12/128 (9%) Query: 32 ASRRALIVIDVQNEYVTGNLPIEYPPIDTSLANIGRAIDAAHAAGVPVIVV-----QHVA 86 +R L++ D+Q Y P+ ANI + + G+PV+ Q+ Sbjct: 28 PNRAVLLIHDMQ-NYFVDAFTAGASPVTELSANIRKLKNQCVQLGIPVVYTAQPGSQNPD 86 Query: 87 PAG--APIFAPGTDGVALHPVVADR----PHAHLIVKAQASAFAGTDLAAWLDAHGIDTL 140 + PG + + ++ K + SAF T+L + G D L Sbjct: 87 DRALLTDFWGPGLNSGPYEEKIITELAPEDDDLVLTKWRYSAFKRTNLLEMMRKEGRDQL 146 Query: 141 SVAGYMTH 148 + G H Sbjct: 147 IITGIYAH 154
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 72.0 bits (176), Expect = 8e-16 Identities = 33/157 (21%), Positives = 60/157 (38%), Gaps = 26/157 (16%) Query: 125 LGSGFIVSADGYILTNAHVIDGANVVTVKLTDKR-----------EYKA-KVVGSDKQSD 172 + SG +V +LTN HV+D + L + A ++ + D Sbjct: 103 IASGVVV-GKDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEGD 161 Query: 173 VAVLKIDA--------SGLPTVKIGDPGQSKVGQWVVAIGSPYGFDNTVTSGIISAKSRA 224 +A++K + + + +++V Q + G P +K + Sbjct: 162 LAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKPVATMW---ESKGKI 218 Query: 225 LPDENYTPFIQTDVPVNPGNSGGPLFNLQGEVIGINS 261 + +Q D+ GNSG P+FN + EVIGI+ Sbjct: 219 TYLKGE--AMQYDLSTTGGNSGSPVFNEKNEVIGIHW 253
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 26.8 bits (59), Expect = 0.023 Identities = 13/83 (15%), Positives = 28/83 (33%), Gaps = 3/83 (3%) Query: 26 LYQW-TGYQPQVYEYFKGQSSPQEQIDALEKALQE--IRAKGHTPPPGFHAHLGMLYASV 82 ++Q +F G + ++ + + A+ A P F H Sbjct: 58 VFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQK 117 Query: 83 GNEQQAEQELQAEKQLFPESSTY 105 G +AE L ++L + + + Sbjct: 118 GELAEAESGLFLAQELIADKTEF 140
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 67.5 bits (165), Expect = 1e-14 Identities = 72/383 (18%), Positives = 125/383 (32%), Gaps = 82/383 (21%) Query: 26 ALAFASQYAAAQSSVTLWGVADASIRYLTNANAKNDGLLSMANG---AITNSRFGIYGTE 82 AL A+ AA + VTL+G A + + S+ G S+ G G E Sbjct: 7 ALTLAALPVAAMADVTLYGTIKAGVETSRSVAHNGAQAASVETGTGIVDLGSKIGFKGQE 66 Query: 83 DLGGGLKAVFNLESGVNLQNGGFADSGRLFNRAAYVGMQSPYGTVTLGRQKTPLFDLLAD 142 DLG GLKA++ +E ++ NR +++G++ +G + +GR + L D Sbjct: 67 DLGNGLKAIWQVEQKASIAGTD----SGWGNRQSFIGLKGGFGKLRVGRLNSVLKD---- 118 Query: 143 TYDPLTVGNYLENAWLPVA--LGGGLYADNQIKYTG------KFAGLTAKAMYSTGTNYE 194 N W + LG A+ + + +FAGL+ Sbjct: 119 --------TGDINPWDSKSDYLGVNKIAEPEARLISVRYDSPEFAGLS------------ 158 Query: 195 STGAGGFSGQIPGSLGKGNAWGVSLSYVAGPLSIA-AGAQQNSDNSARKQTI-------- 245 G+ ++ ++ +Y G + GA + I Sbjct: 159 --GSVQYALNDNAGRHNSESYHAGFNYKNGGFFVQYGGAYKRHHQVQENVNIEKYQIHRL 216 Query: 246 ---YHANVVYAFSKAKVYAGYLRSKDDTGFVDSLLAQQSIPVAKGTGRIDDGPFA-GVSW 301 Y + +YA + ++ +D ++ VA T G VS+ Sbjct: 217 VSGYDNDALYA-------SVAVQQQDAKLVEENYSHNSQTEVA-ATLAYRFGNVTPRVSY 268 Query: 302 QVSTPLTLTGAFYYDHMRNAMTTNGTLASGNRYAIVGIAEYALSKRTEVYGTVDFNKTNG 361 + Y + +VG AEY SKRT + + + Sbjct: 269 AHGFKGSFDATNYNNDYD--------------QVVVG-AEYDFSKRTSALVSAGWLQEGK 313 Query: 362 AANVELPGRSNQTGIAIGLRNIF 384 + T +GLR+ F Sbjct: 314 GE-----SKFVSTAGGVGLRHKF 331
>cloacin#Cloacin signature. Length = 551 Score = 30.1 bits (67), Expect = 0.010 Identities = 20/62 (32%), Positives = 21/62 (33%), Gaps = 14/62 (22%) Query: 224 GGGESGAGSDGSDGS-------DGSN-------GSDGSNGSNGSNGSNGSHPAGHAPRDA 269 G G G SDGS S GS GS NG N GS G+ A Sbjct: 26 GLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVA 85 Query: 270 NP 271 P Sbjct: 86 AP 87
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 27.9 bits (62), Expect = 0.023 Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 2/62 (3%) Query: 110 YVQQGLMPVTAGLVAASAVLISEASNRTAIQWGITAACAVL-AWRTRIHPLWLLAAGALI 168 Y GL+ T GL A +A+LI E + + G A L A R R+ P+ + + ++ Sbjct: 925 YFMVGLL-TTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFIL 983 Query: 169 GL 170 G+ Sbjct: 984 GV 985
>FLAGELLIN#Flagellin signature. Length = 507 Score = 45.4 bits (107), Expect = 3e-07 Identities = 49/367 (13%), Positives = 105/367 (28%), Gaps = 10/367 (2%) Query: 15 QMNDQQAQLAQLYQQIASGVSLQTPADNPVGAAQAVQLSMTSATLSQYATNQTAALASLQ 74 +N Q+ L+ ++++SG+ + + D+ G A A + + L+Q + N ++ Q Sbjct: 16 NLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQASRNANDGISIAQ 75 Query: 75 AEDQALQSVSGVLTGVQTLVVRAGDGSLADSDRSALATQLQGYRDQLMTLANSNDGAGNY 134 + AL ++ L V+ L V+A +G+ +DSD ++ ++Q +++ ++N G Sbjct: 76 TTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEEIDRVSNQTQFNGVK 135 Query: 135 LFAGLNNSSAPFTSSPNGSVSYVGDSGTRQVQIGDSSSVAQGDTGSAVFMSVPSLGSAPV 194 + + N ++ +++ + + + G G V + Sbjct: 136 VLSQDNQMKIQVGANDGETIT---------IDLQKIDVKSLGLDGFNVNGPKEATVGDLK 186 Query: 195 PSAGAANTGTGTITAVTVTTPSAATNGHQFSIAFGGTPAAPTYTVTDNSAKPPTTTAAQA 254 S + G + T Y N Sbjct: 187 SSFKNVTGYDTYAVGANKYRVDVNS-GAVVTDTTAPTVPDKVYVNAANGQLTTDDAENNT 245 Query: 255 YTAGASIALGGGMTVAVSGTPAAGDTFAVTPGPQASGGADIFSTLDSMISALKTPVTGNP 314 T A G T K T N Sbjct: 246 AVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGNGKVSTTING 305 Query: 315 VAAAALSNALMTDSIKVGNTMRNVTTIQASVGGREQEVKAMQAVNQTASLQTTSNLTDLT 374 + + V + + Q + N++A L + Sbjct: 306 EKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSDLEANNAVK 365 Query: 375 STNMTTT 381 + T Sbjct: 366 GESKITV 372
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 219 bits (560), Expect = 1e-65 Identities = 152/444 (34%), Positives = 238/444 (53%), Gaps = 15/444 (3%) Query: 3 NTLMNLGVSGLNAALWGLTTTGQNISNAATPGYSVERPVYAEASGQYTSSGYMPQGVNTV 62 ++L+N +SGLNAA L T NIS+ GY+ + + A+A+ + G++ GV Sbjct: 1 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVS 60 Query: 63 TVQRQYSQYLSDQLNSAQSQGGALSTWYSLVAQLNNYVGSPTAGISTAITGYFTGLQNVA 122 VQR+Y ++++QL +AQ+Q L+ Y +++++N + + T+ ++T + +FT LQ + Sbjct: 61 GVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLV 120 Query: 123 NNASDPSVRQTAISNAQVLADQLKAAGQQYDALRQSVNTQLTSTVSQINTYTSQIAQLNQ 182 +NA DP+ RQ I ++ L +Q K Q + VN + ++V QIN Y QIA LN Sbjct: 121 SNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLND 180 Query: 183 QIA--AASSQGQPPNQLMDQRDLAVSNLSSLAGVQV-VRNDSGYSVFLAGGQPLVVADKS 239 QI+ G PN L+DQRD VS L+ + GV+V V++ Y++ +A G LV + Sbjct: 181 QISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTA 240 Query: 240 YQLATVTSPSDPSELTVVSQGIAGANPPGPNQALPDTSLSGGTLGGLLAFRSQTLDPAQA 299 QLA V S +DPS TV N +P+ L+ G+LGG+L FRSQ LD + Sbjct: 241 RQLAAVPSSADPSRTTVAYVDGTAG-----NIEIPEKLLNTGSLGGILTFRSQDLDQTRN 295 Query: 300 QLGALATSFAAQVNGQNALGIDLSGKPGGNLFAVANPAVYSNQGNTGNASLSVSFTNAAQ 359 LG LA +FA N Q+ G D +G G + FA+ PAV N N G+ ++ + T+A+ Sbjct: 296 TLGQLALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGDVAIGATVTDASA 355 Query: 360 PTTSDYTLSYDGTNYTLTDRASGSVVGQSTSMPASIGGLAFS----FASGSMNAGDQFTV 415 +DY +S+D + +T AS + T P + G +AF +G+ D FT+ Sbjct: 356 VLATDYKISFDNNQWQVTRLASNTT---FTVTPDANGKVAFDGLELTFTGTPAVNDSFTL 412 Query: 416 LPTRGALNGFGLATTSGSAIAAAS 439 P A+ + T + IA AS Sbjct: 413 KPVSDAIVNMDVLITDEAKIAMAS 436 Score = 88.5 bits (219), Expect = 2e-20 Identities = 57/166 (34%), Positives = 84/166 (50%), Gaps = 23/166 (13%) Query: 521 TITSTTQPAPAGVMNGVTVTLSGAPSDGDSFTIGPYAGGT-------------------- 560 T T T +G+ +T +G P+ DSFT+ P + Sbjct: 380 TFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPVSDAIVNMDVLITDEAKIAMASEED 439 Query: 561 ---SDGSNALALSQLVTAKSLGGGTTTLTGAYANYVNAIGNTASQLKSSSAAQTSLVGQI 617 SD N AL L + GG + AYA+ V+ IGN + LK+SSA Q ++V Q+ Sbjct: 440 AGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGNKTATLKTSSATQGNVVTQL 499 Query: 618 TTAQQSVSGVNQNEEAANLMQYQQLYQANAKVIQTAATLFQTVLGL 663 + QQS+SGVN +EE NL ++QQ Y ANA+V+QTA +F ++ + Sbjct: 500 SNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 219 bits (559), Expect = 7e-72 Identities = 127/319 (39%), Positives = 174/319 (54%), Gaps = 41/319 (12%) Query: 16 ALDVQGFDALRAQARQSPQAGAKAVAGQFDAMFTQMMLKSMRDATPDGGLLDSHTSKMYT 75 A D Q + L+A+A + P A + VA Q + MF QMMLKSMRDA P GL S +++YT Sbjct: 12 AWDAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALPKDGLFSSEHTRLYT 71 Query: 76 SMLDQQLAQQMSK-RGIGVADALMKQLMRNAGQGGGTAADAGAAGLGAAGLGAVGAGTSG 134 SM DQQ+AQQM+ +G+G+A+ ++KQ+ Q Sbjct: 72 SMYDQQIAQQMTAGKGLGLAEMMVKQM--TPEQ------------------------PLP 105 Query: 135 NEGSLAAMNAMARAYANAGNNGGLAGARGYSAGSALTPPLKGASGVQ----DADAFVDRL 190 E + AA N L S L + D+ AF+ +L Sbjct: 106 EESTPAAPMKFPLETVVRYQNQAL---------SQLVQKAVPRNYDDSLPGDSKAFLAQL 156 Query: 191 AAPAQAASASTGIPARFIVGQAALESGWGKREIRASDGSTSYNVFGIKANKGWTGRTVSA 250 + PAQ AS +G+P I+ QAALESGWG+R+IR +G SYN+FG+KA+ W G Sbjct: 157 SLPAQLASQQSGVPHHLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEI 216 Query: 251 LTTEYVNGTPRRVVAKFRAYDSYEHAMTDYANLLKNNPRYAGVLSASRSVEGFAHGMQKA 310 TTEY NG ++V AKFR Y SY A++DY LL NPRYA V +A+ + E A +Q A Sbjct: 217 TTTEYENGEAKKVKAKFRVYSSYLEALSDYVGLLTRNPRYAAVTTAASA-EQGAQALQDA 275 Query: 311 GYATDPNYAKKLISIMQQI 329 GYATDP+YA+KL +++QQ+ Sbjct: 276 GYATDPHYARKLTNMIQQM 294
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.0 bits (70), Expect = 0.012 Identities = 12/36 (33%), Positives = 18/36 (50%), Gaps = 3/36 (8%) Query: 49 TPKNILMIGPTGVGKTEIAR---RLAKLADAPFVKI 81 T +++ G +G GK +AR K + PFV I Sbjct: 159 TDLTLMITGESGTGKELVARALHDYGKRRNGPFVAI 194
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 90.3 bits (224), Expect = 1e-23 Identities = 30/127 (23%), Positives = 61/127 (48%) Query: 1 MSENNFLVIDDNEVFAGTLARGLERRGYAVQQAHDKEAALRLAAGGKFQFITVDLHLGED 60 M+ LV DD+ L + L R GY V+ + R A G + D+ + ++ Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 SGLSLIAPLCDLQPDARILVLTGYASIATAVQAVKEGADNYLAKPANIESILAALQTNAS 120 + L+ + +PD +LV++ + TA++A ++GA +YL KP ++ ++ + + Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 121 EVQADEA 127 E + + Sbjct: 121 EPKRRPS 127 Score = 44.4 bits (105), Expect = 7e-08 Identities = 15/101 (14%), Positives = 32/101 (31%), Gaps = 3/101 (2%) Query: 75 DARILVLTGYASIATAVQAVKEGADNYLAKPANIESILAALQTNASEVQADEALENPVVL 134 I+ + I + L+ +E + + + L Sbjct: 375 TREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGL---YDR 431 Query: 135 SVDRLEWEHIQRVLAENNNNISATARALNMHRRTLQRKLAK 175 + +E+ I L N A L ++R TL++K+ + Sbjct: 432 VLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRE 472
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 43.3 bits (102), Expect = 5e-07 Identities = 26/99 (26%), Positives = 48/99 (48%), Gaps = 6/99 (6%) Query: 180 IPVISPIGFGEDGLSYNINADLVAGKLATVLNAEKLLMMTNIPGVM----DKDGNLLTDL 235 +PVI G G+ I+ DL KLA +NA+ +++T++ G + L ++ Sbjct: 197 VPVILEDG-EIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVNGAALYYGTEKEQWLREV 255 Query: 236 SAREIDALFEDGT-ISGGMLPKISSALDAAKSGVKSVHI 273 E+ +E+G +G M PK+ +A+ + G + I Sbjct: 256 KVEELRKYYEEGHFKAGSMGPKVLAAIRFIEWGGERAII 294 Score = 36.7 bits (85), Expect = 8e-05 Identities = 21/60 (35%), Positives = 27/60 (45%), Gaps = 10/60 (16%) Query: 31 GKTVVIKYGGNAMTEERLKQGF----------ARDVILLKLVGINPVIVHGGGPQIDQAL 80 GK VVI GGNA+ + K + AR + + G VI HG GPQ+ L Sbjct: 2 GKRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSLL 61
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 55.8 bits (134), Expect = 8e-12 Identities = 32/178 (17%), Positives = 63/178 (35%), Gaps = 7/178 (3%) Query: 18 PSRPRPKPGERRVMILQTLAAMLEVPKPEKITTAALAARLDVSEAALYRHFASKAKMYEG 77 + + + E R IL + + +A V+ A+Y HF K+ ++ Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 78 LIEFIETTFFGLVNQIAAREPDGVLQA-RAIAMMLLNFAVKNPGMTRVLTGEALVGEDER 136 + E E+ L + A+ P L R I + +L V ++ E + + E Sbjct: 62 IWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLM--EIIFHKCEF 119 Query: 137 LAERVEQMLERIEASLRQALRLAQLDAGAGDRSAATAPLPADYDPSMRASLIVSYVLG 194 + E ++++ + +L LPAD A ++ Y+ G Sbjct: 120 VGEM--AVVQQAQRNLCLESY--DRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISG 173
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 34.0 bits (78), Expect = 0.003 Identities = 71/369 (19%), Positives = 119/369 (32%), Gaps = 91/369 (24%) Query: 201 RARAGEIDPVVGRELEIRTMIDVLLR--RRQNNPLLTGEAGVGKTAVVECLARAIVD--- 255 + + P+VGR ++ + VL R + ++TGE+G GK E +ARA+ D Sbjct: 130 EDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGK----ELVARALHDYGK 185 Query: 256 -----------GDVPPKLADVRLLSLDVGALL-AGASMKGEFEARLKGVLEAATKSAVPV 303 +P L + L + GA A G FE G Sbjct: 186 RRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGT----------- 234 Query: 304 ILFVDEIHTLIGAGGQAGTGDAANLLKPALARGTLRTIGATTW--------AEYKRHIEK 355 LF+DEI G LL+ L +G T+G T A + +++ Sbjct: 235 -LFLDEI-------GDMPMDAQTRLLR-VLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQ 285 Query: 356 D-------PALTRRFQVLQVPEPEEAAAIDMVRGLARTFSRHHGVVVLDEAIRAAVTLSH 408 L R V+ + P + + L R F + Sbjct: 286 SINQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQ---------------AEK 330 Query: 409 RYIPSRQLPDKAISLLDTACARVALSQHAPP---RELQNVRQRLLAAQVECDLLDQERSI 465 + ++ +A+ + H P REL+N+ +RL A L + I Sbjct: 331 EGLDVKRFDQEALE---------LMKAHPWPGNVRELENLVRRLTA-------LYPQDVI 374 Query: 466 GLGDTDALARTQARIAELEREAANVEA-RWRAQADAAQALLSARETARDAASGVPADRLQ 524 + R++ + +E+ AA + + A SG+ L Sbjct: 375 TREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLA 434 Query: 525 VLERALAEQ 533 +E L Sbjct: 435 EMEYPLILA 443
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 504 bits (1300), Expect = 0.0 Identities = 247/348 (70%), Positives = 294/348 (84%), Gaps = 2/348 (0%) Query: 1 MFGFLRSYFSNDLAIDLGTANTLIYMRGKGIVLDEPSVVSIRQEGGPNGKKTIQAVGKEA 60 M R FSNDL+IDLGTANTLIY++G+GIVL+EPSVV+IRQ+ K++ AVG +A Sbjct: 1 MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRA-GSPKSVAAVGHDA 59 Query: 61 KQMLGKVPGNIEAIRPMKDGVIADFTVTEQMIKQFIKTAHESRMFSPSPRIIICVPCGST 120 KQMLG+ PGNI AIRPMKDGVIADF VTE+M++ FIK H + PSPR+++CVP G+T Sbjct: 60 KQMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGAT 119 Query: 121 QVERRAIKEAAHGAGASQVYLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVGVISLG 180 QVERRAI+E+A GAGA +V+LIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEV VISL Sbjct: 120 QVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLN 179 Query: 181 GIVYKGSVRVGGDKFDEAIVNYIRRNYGMLIGEQTAEAIKKEIGSAFPGSEVKEMEVKGR 240 G+VY SVR+GGD+FDEAI+NY+RRNYG LIGE TAE IK EIGSA+PG EV+E+EV+GR Sbjct: 180 GVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGR 239 Query: 241 NLSEGIPRSFTISSNEILEALTDPLNQIVSSVKIALEQTPPELGADIAERGMMLTGGGAL 300 NL+EG+PR FT++SNEILEAL +PL IVS+V +ALEQ PPEL +DI+ERGM+LTGGGAL Sbjct: 240 NLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGAL 299 Query: 301 LRDLDRLLAEETGLPVLVAEDPLTCVVRGSGMALERMDKL-GSIFSYE 347 LR+LDRLL EETG+PV+VAEDPLTCV RG G ALE +D G +FS E Sbjct: 300 LRNLDRLLMEETGIPVVVAEDPLTCVARGGGKALEMIDMHGGDLFSEE 347
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 31.6 bits (71), Expect = 0.006 Identities = 12/81 (14%), Positives = 25/81 (30%), Gaps = 2/81 (2%) Query: 276 QNDVPPRPAEPEPAADKKGKKGAKAAAKGE-KAEKAEKADANAKPSAAAAPGAKPAPAAP 334 N+V +E + + K+ A + + K E + + S + + P Sbjct: 1082 TNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQP 1141 Query: 335 AAPAQPAAAPAKPAAGQPGAP 355 A P +P + Sbjct: 1142 QAEPARENDPTV-NIKEPQSQ 1161
>OMADHESIN#Yersinia outer membrane adhesin signature. Length = 455 Score = 29.9 bits (66), Expect = 0.042 Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 2/84 (2%) Query: 631 QNPKNEAAAVAAAASATEPVSAPVVGDASKPAAVAAGFTALPQPVVPTAASAASAA--DA 688 + P A + A+A ++ +A+K AAVA G ++ V A S A D+ Sbjct: 54 RPPVPGAGGLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDS 113 Query: 689 ASAPDASSAAQPSDASAAAPMAAS 712 A A+S AQ + A + S Sbjct: 114 AVTYGAASTAQKDGVAIGARASTS 137
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 36.7 bits (85), Expect = 6e-05 Identities = 33/171 (19%), Positives = 54/171 (31%), Gaps = 34/171 (19%) Query: 87 RALDAGARTLMFPCIETADEAAHAVRLTRFPSPDAPDGLRGVAGMVRAAAFGMRRDYLQT 146 RA G +MFP I T +E LR +++ + + + Sbjct: 380 RASTYGNLKVMFPMIATLEE------------------LRQAKAIMQEEKDKLLSEGVDV 421 Query: 147 ANAQIAVIVQIESARGIDEVERIAATPGVDCLYVGPADLA----------ASLGHLGDSR 196 ++ I V + +E A VD +G DL + +L Sbjct: 422 SD-SIEVGIMVEIPSTAVAANLFA--KEVDFFSIGTNDLIQYTMAADRMNERVSYLYQPY 478 Query: 197 HPDVETAMARVLAAGKQAGVAVGI---FASDTAIARQYREAGYRMITLSAD 244 HP + + V+ A G VG+ A D G ++SA Sbjct: 479 HPAILRLVDMVIKAAHSEGKWVGMCGEMAGDEVAIPLLLGLGLDEFSMSAT 529