>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 42.8 bits (101), Expect = 2e-06 Identities = 24/56 (42%), Positives = 32/56 (57%), Gaps = 8/56 (14%) Query: 348 LAGLTLNAAKALGIEDKVGSLVVGKQADFCLWNIATPAQLAYSYGVNPCKDVVKNG 403 +A T+N A A G+ ++GSL VGK+AD LWN PA +GV P V+ G Sbjct: 406 IAKYTINPAIAHGLSHEIGSLEVGKRADLVLWN---PAF----FGVKP-DMVLLGG 453 Score = 31.2 bits (71), Expect = 0.008 Identities = 18/61 (29%), Positives = 29/61 (47%), Gaps = 6/61 (9%) Query: 23 YGAITHAAIAVKDGKIAWLGPRSE---LPAFDVL---SIPVYRGKGGWITPGLIDAHTHL 76 + I A I +KDG+IA +G P ++ V G+G +T G +D+H H Sbjct: 80 HWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIVTAGGMDSHIHF 139 Query: 77 V 77 + Sbjct: 140 I 140
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 50.2 bits (120), Expect = 2e-08 Identities = 32/101 (31%), Positives = 48/101 (47%), Gaps = 16/101 (15%) Query: 6 HVDHGKSTLIRALT---------------GMNTDRLPEEKRRGMTIDLGYAFMPLRDGTR 50 HVD GK+TL +L TD E++RG+TI G + T+ Sbjct: 11 HVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSF-QWENTK 69 Query: 51 LAFIDVPGHEKFINNMLVGVSHVRHALLVLACDDGVMPQTR 91 + ID PGH F+ + +S + A+L+++ DGV QTR Sbjct: 70 VNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTR 110
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 29.4 bits (66), Expect = 0.029 Identities = 12/51 (23%), Positives = 14/51 (27%), Gaps = 7/51 (13%) Query: 290 GYAEWTNRAIPSLGDVLFTREAPAGESCLVPENTKVCMGQRMVLLRPDANV 340 GYA+ R P+ VL V M V L P Sbjct: 271 GYADGYPRHAPTGTPVLVDGV-------RTMTVGTVSMDMLAVDLTPCPQA 314
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.6 bits (69), Expect = 3e-04 Identities = 6/22 (27%), Positives = 13/22 (59%) Query: 24 RITEMCQLLGIDRTTLYRRVKR 45 + LLG++R TL ++++ Sbjct: 451 NQIKAADLLGLNRNTLRKKIRE 472
>DNABINDNGFIS#DNA-binding protein FIS signature. Length = 98 Score = 118 bits (297), Expect = 1e-38 Identities = 61/101 (60%), Positives = 83/101 (82%), Gaps = 3/101 (2%) Query: 1 MFDQTTNTEVHQLTVGKIETANGTIKPQLLRDAVKRAVTNFFAQLDGQEAQEVYEMVLSE 60 MF+Q N++V LTV + + + + + LRD+VK+A+ N+FAQL+GQ+ ++YE+VL+E Sbjct: 1 MFEQRVNSDV--LTVSTVNSQDQVTQ-KPLRDSVKQALKNYFAQLNGQDVNDLYELVLAE 57 Query: 61 VEAPLLDIIMQHTRGNQTRAANMLGINRGTLRKKLKKYGMN 101 VE PLLD++MQ+TRGNQTRAA M+GINRGTLRKKLKKYGMN Sbjct: 58 VEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN 98
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 332 bits (853), Expect = e-117 Identities = 171/303 (56%), Positives = 205/303 (67%), Gaps = 15/303 (4%) Query: 6 TLLGHTFDQAPWLFISLSFVFAATIGSFLNVVIHRFPVMMKREWQQECNQYLQEYHADIV 65 LL PWL+ SL F+F+ IGSFLNVVIHR P+M++REWQ E Y + Sbjct: 2 ALLLELAHGLPWLYFSLVFLFSLMIGSFLNVVIHRLPIMLEREWQAEYRSYFNPDDEGVD 61 Query: 66 KQVGIDKLSKAIDHYPPKYNLVVPGSACPKCKTAIKPWHNLPMLGWLMLRGKCAACSAPI 125 P YNL+VP S CP C I N+P+L WL LRG+C C API Sbjct: 62 ---------------EPPYNLMVPRSCCPHCNHPITALENIPLLSWLWLRGRCRGCQAPI 106 Query: 126 SARYPIIELITGLLVATLAWHFGPSWQFVFAAILTFVLIALTGIDLDEMLLPDQMTLPLL 185 SARYP++EL+T LL +A P W + A +LT+VL+ALT IDLD+MLLPDQ+TLPLL Sbjct: 107 SARYPLVELLTALLSVAVAMTLAPGWGTLAALLLTWVLVALTFIDLDKMLLPDQLTLPLL 166 Query: 186 WLGLLINLNHTFTSPADAMIGAAAGYLSLWSIFWLFKLLTGKEGMGYGDFKLLAVFGAWL 245 W GLL NL F S DA+IGA AGYL LWS++W FKLLTGKEGMGYGDFKLLA GAWL Sbjct: 167 WGGLLFNLLGGFVSLGDAVIGAMAGYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWL 226 Query: 246 GWQMLPLVILLSSLVGAFVGITLIVTKRNQLANPIPFGPYIAAAGWIALIWGQPIVDWYL 305 GWQ LP+V+LLSSLVGAF+GI LI+ + + + PIPFGPY+A AGWIAL+WG I WYL Sbjct: 227 GWQALPIVLLLSSLVGAFMGIGLILLRNHHQSKPIPFGPYLAIAGWIALLWGDSITRWYL 286 Query: 306 STL 308 + Sbjct: 287 TNF 289
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 388 bits (997), Expect = e-135 Identities = 119/405 (29%), Positives = 213/405 (52%), Gaps = 9/405 (2%) Query: 25 TFEWKGVNRDGQKTSGELRGASAAEIRSQLKSQGVNP--------KTVRKQSAALFKLGD 76 + ++ ++ G+K G SA + R L+ +G+ P + S L Sbjct: 3 QYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLRRK 62 Query: 77 PKITPMDIAMVTRQIATMLAAGVPLVTTIELLGRGHEKVKMRELLATILSEIQSGIPLSD 136 +++ D+A++TRQ+AT++AA +PL ++ + + EK + +L+A + S++ G L+D Sbjct: 63 IRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLAD 122 Query: 137 ALRPHRRYFDDLYVDLVAAGEHSGSLDVVFDRIATYREKSEALKSKIKKAMFYPAAVVIV 196 A++ F+ LY +VAAGE SG LD V +R+A Y E+ + ++S+I++AM YP + +V Sbjct: 123 AMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLTVV 182 Query: 197 AILVTALLLLFVVPQFEDIFKGFGAELPAFTQLVLQISRGLQSSWYIFLGAIVAGVFLFV 256 AI V ++LL VVP+ + F LP T++++ +S +++ L A++AG F Sbjct: 183 AIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMAF- 241 Query: 257 RAHRNSQIVRDRVDEAVLKIPAIGPILHKGAMARFARTLATTFAAGVPLIDGLESAAGAS 316 R + R +L +P IG I AR+ARTL+ A+ VPL+ + + Sbjct: 242 RVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDVM 301 Query: 317 GNAVYRKAILKIRQEVMAGMQMNVAMRTTGLFPDMLIQMVMIGEESGSLDNMLNKVSTIY 376 N R + V G+ ++ A+ T LFP M+ M+ GE SG LD+ML + + Sbjct: 302 SNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADNQ 361 Query: 377 EMQVDDAVDGLSSLIEPIMMVVIGTVVGGLIVAMYLPIFQMGKVV 421 + + + L EP+++V + VV +++A+ PI Q+ ++ Sbjct: 362 DREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 79.3 bits (195), Expect = 1e-19 Identities = 51/184 (27%), Positives = 82/184 (44%), Gaps = 2/184 (1%) Query: 3 GLTGKVVIITGASEGIGRALAIAMARIGCQLVLSARNETRLASLALEVANYGPTPFVFAA 62 G+ GK+ ITGA++GIG A+A +A G + N +L + + F A Sbjct: 5 GIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPA 64 Query: 63 DVSSASQCEDLIHATIAHYGRIDILVNNAGMTMWSRFDELTQLSVLEDIMRVNYLGPAYL 122 DV ++ +++ G IDILVN AG+ L+ E VN G Sbjct: 65 DVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEW-EATFSVNSTGVFNA 123 Query: 123 THAALPYLKSSQ-GQVVIVASVAGLTGVPTRSGYAASKHAVIGFFDSLRIELADDNVAVT 181 + + Y+ + G +V V S + + YA+SK A + F L +ELA+ N+ Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 182 VICP 185 ++ P Sbjct: 184 IVSP 187
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 40.2 bits (94), Expect = 9e-06 Identities = 35/172 (20%), Positives = 59/172 (34%), Gaps = 7/172 (4%) Query: 215 GLLLGPIYGLLPIYVSQDMGFAQQ---TGQFMALIILGGMIVQPLVSYLSPRIQKSVLMI 271 + +G I +LP + + G +AL L P++ LS R + ++ Sbjct: 18 AVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRR-PVL 76 Query: 272 AFCLVGAAALLLLMQTSLVGLWLGFV--LLGACAFALYPIAISLACDHLPSSQIVSATQI 329 L GAA +M T+ LW+ ++ ++ A +A + D + Sbjct: 77 LVSLAGAAVDYAIMATAPF-LWVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGF 135 Query: 330 MLLSYSVGSVIGPVAASRFDDIEHGLPLYLAASFLMTACYLSAHLLARSKAR 381 M + G V GPV P + AA+ LL S Sbjct: 136 MSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKG 187 Score = 30.9 bits (70), Expect = 0.009 Identities = 33/151 (21%), Positives = 64/151 (42%), Gaps = 6/151 (3%) Query: 12 LFVPVAGLSLFALASGYLMSLIPLSLTYFDLSLDLAP---WLASIFYLGLLLGAPCIAPI 68 L V ++ ++L A+ G +M ++P L S D+ L +++ L AP + + Sbjct: 7 LIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGAL 66 Query: 69 VSRIGHSKAFILFLNILLCSVVVMVLLPQTSIWLASRLIAGLAVAGIFVVVESWLLMADT 128 R G ++ L +M P + R++AG+ A V +++ Sbjct: 67 SDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGA-TGAVAGAYIADITD 125 Query: 129 QKQRAKRLGLYMTALYG-GTAIGQLAVDYLG 158 +RA+ G +M+A +G G G + +G Sbjct: 126 GDERARHFG-FMSACFGFGMVAGPVLGGLMG 155
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 68.9 bits (168), Expect = 1e-17 Identities = 38/96 (39%), Positives = 50/96 (52%), Gaps = 2/96 (2%) Query: 12 GDGKEAVKGALITTQYRGFLQDGTQFDSSYDRGQAFQCVIGTGRVIKGWDQGIMGMKVGG 71 G G + K +T +Y G L DGT FDS+ G+ +VI GW + + M G Sbjct: 136 GTGAKPGKSDTVTVEYTGTLIDGTVFDSTEKAGKP--ATFQVSQVIPGWTEALQLMPAGS 193 Query: 72 KRKLLVPAHLAYGERQVGAHIKPNSDLTFEIELLEV 107 ++ VPA LAYG R VG I PN L F+I L+ V Sbjct: 194 TWEVFVPADLAYGPRSVGGPIGPNETLIFKIHLISV 229
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 181 bits (461), Expect = 4e-59 Identities = 99/227 (43%), Positives = 135/227 (59%), Gaps = 9/227 (3%) Query: 21 ALFVSMASFAAPSLKTDADKASYSIGASVGNYISGQVYNQVELGAEVNVDLVVQGFVDAL 80 A+ +MA+ A SL TD DK SYSIGA +G Q G ++N D++ +G D + Sbjct: 14 AMSTAMAATDATSLTTDKDKLSYSIGADLGKNFKNQ-------GIDINPDVLAKGMQDGM 66 Query: 81 K-KQQQLTDEEVVTYLNQRAEELNQVRKANAEKLAAENIKAGEAFLAENKKKAGVTVTES 139 Q LT+E++ L++ ++L R A K A EN G+AFL+ NK K G+ V S Sbjct: 67 SGAQLILTEEQMKDVLSKFQKDLMAKRSAEFNKKAEENKAKGDAFLSANKSKPGIVVLPS 126 Query: 140 GLQYEVLTKGTGNKPNPEDVVTVEYVGKLIDGTEFENTVGRKEPTRFALMTVIPGWEEGL 199 GLQY+++ GTG KP D VTVEY G LIDGT F++T +P F + VIPGW E L Sbjct: 127 GLQYKIIDAGTGAKPGKSDTVTVEYTGTLIDGTVFDSTEKAGKPATFQVSQVIPGWTEAL 186 Query: 200 KLMPMGSKYRFVIPANLAYGNEFV-GEIPPQSTLIFEIELKNIEKPS 245 +LMP GS + +PA+LAYG V G I P TLIF+I L +++K + Sbjct: 187 QLMPAGSTWEVFVPADLAYGPRSVGGPIGPNETLIFKIHLISVKKAA 233
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 31.2 bits (70), Expect = 0.004 Identities = 16/78 (20%), Positives = 26/78 (33%) Query: 143 PTGYDDTPVAISAPVRVTTSMQYSPSEGRMVSNMPSNSATVISAASTARASTVSAEQTVA 202 P +T P + T+S P N ++ + A ++ Sbjct: 1158 PQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSN 1217 Query: 203 VPRARAARSVSSLPSNAR 220 P+ R RSV S+P N Sbjct: 1218 KPKNRHRRSVRSVPHNVE 1235
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 48.5 bits (115), Expect = 5e-09 Identities = 41/183 (22%), Positives = 80/183 (43%), Gaps = 5/183 (2%) Query: 2 ILITGASSGLGAALAALYAKDNQALTLTGRDANRLHTVANALSPFSQQAITAIAADLSDE 61 ITGA+ G+G A+A A + + +L V ++L ++ A A AD+ D Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHA-EAFPADVRDS 69 Query: 62 ASVEALFDGLTDSPA---TVIHCAGSGYFGALENQGAREIKTLLNNNVTSTILLVRELVK 118 A+++ + + +++ AG G + + E + + N T R + K Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSK 129 Query: 119 RYKNQ-AITVVVVMSTAALAAKAGESTYCAAKWAVRGFIESVRLELKQSPMKLIAVYPGG 177 ++ + ++V V S A + + Y ++K A F + + LEL + ++ V PG Sbjct: 130 YMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGS 189 Query: 178 MDT 180 +T Sbjct: 190 TET 192
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 28.3 bits (63), Expect = 0.014 Identities = 9/23 (39%), Positives = 11/23 (47%) Query: 126 GIIGAIWVKEGDEVAFDQPLFTL 148 I+ I VKEG+ V L L Sbjct: 105 SIVKEIIVKEGESVRKGDVLLKL 127
>TRNSINTIMINR#Translocated intimin receptor (Tir) signature. Length = 549 Score = 27.4 bits (60), Expect = 0.022 Identities = 11/27 (40%), Positives = 18/27 (66%), Gaps = 2/27 (7%) Query: 31 DIVAQLNEQAQAAGVQL--EHIQSNAE 55 DIV Q+ +QA+ AG + ++SNA+ Sbjct: 316 DIVEQIAQQAKEAGEVARQQAVESNAQ 342
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.1 bits (73), Expect = 0.004 Identities = 16/160 (10%), Positives = 48/160 (30%), Gaps = 10/160 (6%) Query: 76 EVQAQIARQQQAELAIAAADRAVYNPEL-GLNYQNSETDTYTVGLSQTLDWGDKRGVATR 134 + + QA L + EL L + Y +S+ + + Sbjct: 135 DTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQ 194 Query: 135 LAQLEAQILLADIRLERSQMLAERLLALAEQAQGQKALTFAEQQLRFTQAQLNIAEQRFA 194 + + Q ++ L++ + AE+ + E R +++L+ Sbjct: 195 FSTWQNQKYQKELNLDKKR---------AERLTVLARINRYENLSRVEKSRLDDFSSLLH 245 Query: 195 AGDLSDVELQLLKLELASNTADYALAEQAALVAEGKVIEL 234 ++ + + + + + + E +++ Sbjct: 246 KQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSA 285
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 54.8 bits (132), Expect = 3e-10 Identities = 29/138 (21%), Positives = 56/138 (40%), Gaps = 9/138 (6%) Query: 161 EVAKAQAEYINAAAEWSRVRR---MSEGAVSVSRRMQAQVDAELKRAILEAIKMTSEQIR 217 V + + +Y+ A E + E + ++ V K IL+ ++ T++ I Sbjct: 253 AVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIG 312 Query: 218 TLESKPEA----IGSYQLLAPIDGRVQQ-DIAMLGQVFSAGTPLMQLT-DESHLWVEAQL 271 L + + + AP+ +VQQ + G V + LM + ++ L V A + Sbjct: 313 LLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALV 372 Query: 272 TPAQAVNVKVGAPALIQV 289 + VG A+I+V Sbjct: 373 QNKDIGFINVGQNAIIKV 390 Score = 42.5 bits (100), Expect = 2e-06 Identities = 26/149 (17%), Positives = 54/149 (36%), Gaps = 5/149 (3%) Query: 105 SLTNLNLDVRATATLVVDRDKTATLAPQLDVRVQARHVVPGQEVKKGEPLLTLGG----A 160 L + + A L ++ + P + V+ V G+ V+KG+ LL L A Sbjct: 76 VLGQVEIVATANGKLTHS-GRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEA 134 Query: 161 EVAKAQAEYINAAAEWSRVRRMSEGAVSVSRRMQAQVDAELKRAILEAIKMTSEQIRTLE 220 + K Q+ + A E +R + +S D + + E + + + Sbjct: 135 DTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQ 194 Query: 221 SKPEAIGSYQLLAPIDGRVQQDIAMLGQV 249 YQ +D + + + +L ++ Sbjct: 195 FSTWQNQKYQKELNLDKKRAERLTVLARI 223
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 656 bits (1693), Expect = 0.0 Identities = 224/1082 (20%), Positives = 434/1082 (40%), Gaps = 74/1082 (6%) Query: 9 AIKNRLLVVLALLAAVAASVAMLPKLNLDAFPDVTNVQVTINTEAEGLAAEEVEKLISYP 68 I+ + + + + A + +L + +P + V+++ G A+ V+ ++ Sbjct: 5 FIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQV 64 Query: 69 VESAMYALPAVTEVRSLS-RTGLSIVTVVFAEGTDIYFARQQVFEQLQAAREMIPSGVGV 127 +E M + + + S S G +T+ F GTD A+ QV +LQ A ++P V Sbjct: 65 IEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQQ 124 Query: 128 PEIGPNTSGLGQIYQYILRADPSAGINAAELRSLNDYLVKLILMPVGGVTDVLSFGGEVR 187 I S + +D + G ++ VK L + GV DV FG + Sbjct: 125 QGISVEKSSSSYLMVAGFVSD-NPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQ-Y 182 Query: 188 QYQVQVDPNKLRAYGLSMAQVSEALESNNRNAGGWFMDQGQEQLVVRGYGMLPAGEAGLA 247 ++ +D + L Y L+ V L+ N + G L + + Sbjct: 183 AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLG-GTPALPGQQLNASIIAQTRFK 241 Query: 248 SIAQIPLTEVR----GTPVRVGDIAKVDFGSEIRVGAVTMTRRDEAGQAQALGEVVAGVV 303 + + +R G+ VR+ D+A+V+ G E + G+ + Sbjct: 242 NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARIN-----GK-----PAAGLGI 291 Query: 304 LKRMGANTKATIDDIDARINLIEQALPKGVSFEVFYDQADLVDKAVATVRDALLMAFVFI 363 GAN T I A++ ++ P+G+ YD V ++ V L A + + Sbjct: 292 KLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLV 351 Query: 364 VVILALFLVNIRATLLVLLSIPVSIGLALMVMSYYGLSANLMSLGGLAVAIGMLVDGSVV 423 +++ LFL N+RATL+ +++PV + +++ +G S N +++ G+ +AIG+LVD ++V Sbjct: 352 FLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIV 411 Query: 424 MVENIFKHLTQPDRRHLTQARARADGEADPYHGDEDGGVNADDDDHQGNMAVRIMLAAKE 483 +VEN+ R + + P + + Sbjct: 412 VVENV--------------ERVMMEDKLPPKEA--------------------TEKSMSQ 437 Query: 484 VCSPIFFATAIIIVVFAPLFALEGVEGKLFQPMAVSIILAMISALLVALIAVPALAVYLF 543 + + ++ VF P+ G G +++ +++I+ AM ++LVALI PAL L Sbjct: 438 IQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLL 497 Query: 544 K----------RGVVLKESVILRPLDNAYRKLLSATLARPKMVVLSAVIMFVMSMALLPR 593 K G + N Y + L +L ++ + L R Sbjct: 498 KPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLR 557 Query: 594 LGTEFVPELEEGTINLRVTLAPTASLGTSLDVAPKLEALLLQFPEVEYALSRIGAPELGG 653 L + F+PE ++G + L A+ + V ++ L+ + S Sbjct: 558 LPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNEKANVE-SVFTVNGFSF 616 Query: 654 DPEPVSNIEIYIGLKPIEEWQSASSRLA--LQRLMEEKLSVFPGLLLTFSQPIATRVDEL 711 + + ++ LKP EE + + R E + G ++ F+ P + EL Sbjct: 617 SGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGFVIPFNMP---AIVEL 673 Query: 712 LSGVKAQLA-IKLFGPDLAVLSDKGQVLTDLVAKIPGAV-DVSLEQVSGEAQLVVRPDRS 769 + I G L+ L + A+ P ++ V + AQ + D+ Sbjct: 674 GTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQE 733 Query: 770 QLARYGISVDQVMTLVSQGIGGASAGQVIDGNARYDINLRLAAEFRSSPDVIKDLLLSGT 829 + G+S+ + +S +GG ID + ++ A+FR P+ + L + Sbjct: 734 KAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSA 793 Query: 830 NGAIVRLGEVASVEVEMAPPNIRRDDVQRRVVVQANVA-GRDMGSIVNDIYALVPKADLP 888 NG +V + P + R + + +Q A G G + + L K LP Sbjct: 794 NGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASK--LP 851 Query: 889 AGYTVIVGGQYENQQRAQQKLMLVVPVSIALIALLLYFSFGAVKQVLLIMANVPLALIGG 948 AG G ++ + + +V +S ++ L L + + + +M VPL ++G Sbjct: 852 AGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGV 911 Query: 949 IVALFVSGTYLSVPSSIGFITLFGVAVLNGVVLVDSINQ-RRQSGESLYDSVYEGTVGRL 1007 ++A + V +G +T G++ N +++V+ + G+ + ++ RL Sbjct: 912 LLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRL 971 Query: 1008 RPVLMTALTSALGLIPILVSSGVGSEIQKPLAVVIIGGLFSSTALTLLVLPTLYRWLYRR 1067 RP+LMT+L LG++P+ +S+G GS Q + + ++GG+ S+T L + +P + + R Sbjct: 972 RPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRRC 1031 Query: 1068 DK 1069 K Sbjct: 1032 FK 1033 Score = 99.1 bits (247), Expect = 4e-23 Identities = 92/512 (17%), Positives = 192/512 (37%), Gaps = 37/512 (7%) Query: 575 MVVLSAVIMFVMSMALLPRLGTEFVPELEEGTINLRVTLAPTASLGTSLD-VAPKLEALL 633 VL+ ++M ++A+L +L P + +++ P A T D V +E + Sbjct: 12 AWVLAIILMMAGALAIL-QLPVAQYPTIAPPAVSVSAN-YPGADAQTVQDTVTQVIEQNM 69 Query: 634 LQFPEVEYALSRIGAPELGGDPEPVSNIEIYIGLKPIEEWQSASSRLALQRLMEEKLSVF 693 + Y S + ++ I + + +A ++ KL + Sbjct: 70 NGIDNLMYMSST---------SDSAGSVTITLTFQS-----GTDPDIAQVQVQN-KLQLA 114 Query: 694 PGLLLTFSQPIATRVDELLSGVKAQLAIKLFGPDL--AVLSDKGQ-VLTDLVAKIPGAVD 750 LL Q V++ S P +SD + D ++++ G D Sbjct: 115 TPLLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGD 174 Query: 751 VSLEQVSGEAQLVVRPDRSQLARYGISVDQVMTLVSQGIGGASAGQVIDGNARYDINLRL 810 V L + + + D L +Y ++ V+ + +AGQ+ A L Sbjct: 175 VQL--FGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNA 232 Query: 811 A----AEFRSSPDVIKDLLLSGTNGAIVRLGEVASVEVEMAPPNIR-RDDVQRRVVVQAN 865 + F++ + K L ++G++VRL +VA VE+ N+ R + + + Sbjct: 233 SIIAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIK 292 Query: 866 VA-GRDMGSIVNDIYALVP--KADLPAGYTVIVGGQYENQQRAQQKLMLVVP---VSIAL 919 +A G + I A + + P G V+ Y+ Q + VV +I L Sbjct: 293 LATGANALDTAKAIKAKLAELQPFFPQGMKVLY--PYDTTPFVQLSIHEVVKTLFEAIML 350 Query: 920 IALLLYFSFGAVKQVLLIMANVPLALIGGIVALFVSGTYLSVPSSIGFITLFGVAVLNGV 979 + L++Y ++ L+ VP+ L+G L G ++ + G + G+ V + + Sbjct: 351 VFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAI 410 Query: 980 VLVDSINQRRQS-GESLYDSVYEGTVGRLRPVLMTALTSALGLIPILVSSGVGSEIQKPL 1038 V+V+++ + ++ + ++ A+ + IP+ G I + Sbjct: 411 VVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQF 470 Query: 1039 AVVIIGGLFSSTALTLLVLPTLYRWLYRRDKR 1070 ++ I+ + S + L++ P L L + Sbjct: 471 SITIVSAMALSVLVALILTPALCATLLKPVSA 502
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 44.3 bits (104), Expect = 8e-08 Identities = 37/177 (20%), Positives = 62/177 (35%), Gaps = 25/177 (14%) Query: 3 ILVVGAAGNIGQAVTRLLKAEGHQVIQV-----------------GRTRGDLLMDICDPN 45 + GAA IG+AV R L ++G + V R D+ D Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSA 70 Query: 46 SLQQGFNQL----GKVDAIIAAMGDVAFKPFVQLDQADWQKGIQSKLLGQIQLVQIGSQF 101 ++ + ++ G +D ++ G + L +W+ G + S++ Sbjct: 71 AIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSKY 130 Query: 102 LNA--GGSFTLTSGIIADVPVKDGVSAATINGALEHFVAAVANELPQQ--RINIVSP 154 + GS A VP + A+ A F + EL + R NIVSP Sbjct: 131 MMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 550 bits (1420), Expect = 0.0 Identities = 185/689 (26%), Positives = 300/689 (43%), Gaps = 70/689 (10%) Query: 6 KYRNIGIFAHVDAGKTTTTERILKLTGKIHKIGEVHDGESTTDFMVQEAERGITIQSAAV 65 K NIG+ AHVDAGKTT TE +L +G I ++G V G + TD + E +RGITIQ+ Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 66 SCFWKDHRFNVIDTPGHVDFTVEVYRSLKVLDGGIAVFCGSGGVEPQSETNWRYANESEV 125 S W++ + N+IDTPGH+DF EVYRSL VLDG I + GV+ Q+ + + + Sbjct: 62 SFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGI 121 Query: 126 ARIIFVNKLDRMGADFLRVVKQTKDVLAANPLVMVLPIGIEDEFCGVVDLLTRKAYVWDD 185 I F+NK+D+ G D V + K+ L+A ++ Sbjct: 122 PTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQ------------------------- 156 Query: 186 SGIPENFEVKDVPANMVDLVEEYREMLIETAVEQDDDLLEAYMEGEEPSIEDLKRCIRKG 245 +V+ P V E + +T +E +DDLLE YM G+ +L++ Sbjct: 157 -------KVELYPNMCVTNFTESEQ--WDTVIEGNDDLLEKYMSGKSLEALELEQEESIR 207 Query: 246 TRTMAFFPTFCGSAFKNKGMQLVLDAVVDYLPAPDEVDPQPLTDEEGNETGEYAIVSADE 305 + FP + GSA N G+ +++ + + + T +E Sbjct: 208 FHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSS--------THRGQSE----------- 248 Query: 306 SLKALAFKI-MDDRFGALTFVRIYAGRLKKGDTILNSATGKTERIGRMCEMYANDRIEIE 364 L FKI ++ L ++R+Y+G L D++ S K +I M + +I+ Sbjct: 249 -LCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEK-IKITEMYTSINGELCKID 306 Query: 365 SAEAGDIIAIVGMKNVQTGHTLCDVKHPCTLEAMVFPEPVISIAVAPKDKGGSEKMAIAI 424 A +G+I+ + + ++ L D K E + P P++ V P E + A+ Sbjct: 307 KAYSGEIVILQN-EFLKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQREMLLDAL 365 Query: 425 GKMIAEDPSFRVETDEDSGETILKGMGELHLDIKVDILKRTYGVELIVGEPQVAYRETIT 484 ++ DP R D + E IL +G++ +++ +L+ Y VE+ + EP V Y E Sbjct: 366 LEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIKEPTVIYMERPL 425 Query: 485 AMVEDQYTHKKQSGGSGQFGKIEYIIRPGEPNSGFVFKSSVVGGSVPKEFWPAVEKGFAS 544 E YT + + + I + P SG ++SSV G + + F AV +G Sbjct: 426 KKAE--YTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRY 483 Query: 545 MMNTGTIAGFPVLDVEFELTDGAYHAVDSSAIAFEIAAKAAFRQSIAKAKPQLLEPIMKV 604 G + G+ V D + G Y++ S+ F + A Q + KA +LLEP + Sbjct: 484 GCEQG-LYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSF 542 Query: 605 DVFSPDDNVGDVIGDLNRRRGMIKDQVAGITGVRVKADVPLSEMFGYIGSLRTMTSGRGQ 664 +++P + + D + I D V + ++P + Y L T+GR Sbjct: 543 KIYAPQEYLSRAYTDAPKYCANIVDTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSV 602 Query: 665 FSMEFSHYSPC----------PNSVADKV 683 E Y PNS DKV Sbjct: 603 CLTELKGYHVTTGEPVCQPRRPNSRIDKV 631
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 31.4 bits (71), Expect = 0.026 Identities = 14/71 (19%), Positives = 31/71 (43%), Gaps = 5/71 (7%) Query: 354 AGLEPLTIDAQTLFVNVGERTN---VTGSAKFLKLIKEGKFEQALDVAREQVESGAQIID 410 +P+ + + + +TN VT + + ++ + LD+ R QV A I + Sbjct: 298 QAAKPVAALDKNIIIKAHGQTNALIVTAAPDVMNDLE--RVIAQLDIRRPQVLVEAIIAE 355 Query: 411 INMDEGMLDGV 421 + +G+ G+ Sbjct: 356 VQDADGLNLGI 366
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 28.8 bits (64), Expect = 0.022 Identities = 15/70 (21%), Positives = 25/70 (35%), Gaps = 4/70 (5%) Query: 159 AIAAILEQAFACLPLGDKPADAAADTAANIWVVTH--GGVIRHLMARALGAVKAVGFYSQ 216 ++ IL A L + AD AA + + T G V + + + A G Sbjct: 244 TVSGILSAISASFILSNADADTRTKAAAGVELTTKVLGNVGKGISQYIIAQRAAQGL--S 301 Query: 217 LTLPVAALVT 226 + A L+ Sbjct: 302 TSAAAAGLIA 311
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.012 Identities = 11/54 (20%), Positives = 20/54 (37%), Gaps = 4/54 (7%) Query: 29 DVALNVSQLSWTIEGKTILSGVNFALQRG----EMLGLIGPNGAGKSSLLRCLY 78 D + + ++ V ++ G + L G G GKS+L+ L Sbjct: 564 DYKPRRLRYLQLVGKYILMGHVARVMEPGCKFDYSVVLEGTGGIGKSTLINTLV 617
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 140 bits (354), Expect = 6e-39 Identities = 80/386 (20%), Positives = 146/386 (37%), Gaps = 81/386 (20%) Query: 5 IGIDLGTTNSCVAVLDGGK-----ARVLENAEGDRTTPSIIAYTDDETIVGQPAKRQAVT 59 + IDLGT N+ + V G + V + + S+ A VG AK+ Sbjct: 13 LSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAA-------VGHDAKQMLGR 65 Query: 60 NPNNTFFAIKRLIGRRFKDDEVQRDVNIMPFKIIAADNGDAWVESRGNKMAPPQVSAEIL 119 P N AI+ + +D I F V+ ++L Sbjct: 66 TPGN-IAAIRPM-----------KDGVIADFF----------------------VTEKML 91 Query: 120 KK-MKKTAEDFLGEEVTEAVITVPAYFNDSQRQATKDAGRIAGLEVKRIINEPTAAALAY 178 + +K+ + ++ VP +R+A +++ + AG +I EP AAA+ Sbjct: 92 QHFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGA 151 Query: 179 GIDKKQGDNIVAVYDLGGGTFDISIIEIDSNDGDQTFEVLATNGDTHLGGEDFDNRLINY 238 G+ + + V D+GGGT ++++I ++ + + +GG+ FD +INY Sbjct: 152 GLPVSEATGSM-VVDIGGGTTEVAVISLNG---------VVYSSSVRIGGDRFDEAIINY 201 Query: 239 LADEFKKEQGLDLRKDPLAMQRLKEAAEKAKIELSST----NQTEVNLPYITADATGPKH 294 + + G + AE+ K E+ S E+ + P+ Sbjct: 202 VRRNYGSLIG-------------EATAERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRG 248 Query: 295 LVVKITRAKLESLVEDLIIRTLEPLKVALADA--DLSVSDINE--VILVGGQTRMPKVQE 350 + + LE+L E + + + VAL +L+ SDI+E ++L GG + + Sbjct: 249 FTLN-SNEILEALQEP-LTGIVSAVMVALEQCPPELA-SDISERGMVLTGGGALLRNLDR 305 Query: 351 AVTNFFGKEPRKDVNPDEAVAVGAAI 376 + G +P VA G Sbjct: 306 LLMEETGIPVVVAEDPLTCVARGGGK 331
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 160 bits (407), Expect = 9e-52 Identities = 79/205 (38%), Positives = 124/205 (60%), Gaps = 9/205 (4%) Query: 6 STVEQQASYGVGRQMGEQLAANSFEGVDI-PAVQA-GLADAFAGLESAVSMQELQVAFTE 63 +T + + SY +G +G+ +G+DI P V A G+ D +G + ++ ++++ ++ Sbjct: 28 TTDKDKLSYSIGADLGKNFKN---QGIDINPDVLAKGMQDGMSGAQLILTEEQMKDVLSK 84 Query: 64 ISRRIQAAQ----EQAAAEASAEGEAFLVENANREGVIVTESGLQYEVLVQGNGAKPTYE 119 + + A + + A E A+G+AFL N ++ G++V SGLQY+++ G GAKP Sbjct: 85 FQKDLMAKRSAEFNKKAEENKAKGDAFLSANKSKPGIVVLPSGLQYKIIDAGTGAKPGKS 144 Query: 120 DTVRTHYHGSFINGDVFDSSVVRGQPAEFPVSGVIAGWTEALQLMPVGTKLKLYVPHHLA 179 DTV Y G+ I+G VFDS+ G+PA F VS VI GWTEALQLMP G+ +++VP LA Sbjct: 145 DTVTVEYTGTLIDGTVFDSTEKAGKPATFQVSQVIPGWTEALQLMPAGSTWEVFVPADLA 204 Query: 180 YGERGAGASIPPYSTLVFEVELLDI 204 YG R G I P TL+F++ L+ + Sbjct: 205 YGPRSVGGPIGPNETLIFKIHLISV 229
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 50.8 bits (121), Expect = 8e-10 Identities = 28/169 (16%), Positives = 57/169 (33%), Gaps = 12/169 (7%) Query: 15 QILDAAEKLIESQGVVSFKFSQLAHEVGCSTGTLYKFFERKEDVLVCLFLR-----SATS 69 ILD A +L QGV S ++A G + G +Y F+ K D+ ++ Sbjct: 15 HILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELE 74 Query: 70 NHLPIFIHKNPELTAQEKVLLPILFTFETIKRSSSFFTLRSVSVNTMVWKLASDEKVERF 129 +P +E ++ + T +R + V++ Sbjct: 75 LEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEM-----AVVQQA 129 Query: 130 KKRIN-AFWSWFTDSLHLAVENGELVATPLQIKELVQGITFYLTGSLTQ 177 ++ + + +L +E L A L + + Y++G + Sbjct: 130 QRNLCLESYDRIEQTLKHCIEAKMLPA-DLMTRRAAIIMRGYISGLMEN 177
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 98.0 bits (244), Expect = 3e-26 Identities = 24/120 (20%), Positives = 58/120 (48%) Query: 4 LYLVDDDQDVLDSLSWMLEGMGLNCKGFNAADAFLKSVDIKQPAVLLLDIKMPGMDGVAL 63 + + DDD + L+ L G + + + A + + +++ D+ MP + L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 64 LNHLNQAQSAISVIMLTGHGTIAMAVDCIQQGALNFLEKPVDGEKLFQLLTQAQQHTEQK 123 L + +A+ + V++++ T A+ ++GA ++L KP D +L ++ +A +++ Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRR 125
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 69.4 bits (170), Expect = 2e-15 Identities = 87/358 (24%), Positives = 129/358 (36%), Gaps = 40/358 (11%) Query: 1 MNKSFAISLLTLALCATQAVADEHKFYGRIDYSVTHSDS----GSATHKNKSGTILENNF 56 M KS L A A YG I V S S G+ ++GT + + Sbjct: 1 MKKSLIALTLAALPVAAMADVT---LYGTIKAGVETSRSVAHNGAQAASVETGTGIVDLG 57 Query: 57 SRFGIKGSSQLTDSTSLFYQIEVGVNGESQDSGDKPFSARPTFIGVKHSTYGALAVGRID 116 S+ G KG L + +Q+E + DSG R +FIG+K +G L VGR++ Sbjct: 58 SKIGFKGQEDLGNGLKAIWQVEQKASIAGTDSGWG---NRQSFIGLK-GGFGKLRVGRLN 113 Query: 117 PVFKMAKGMSDAMDNYSLKHDRLFAGDKRWGDSFEYKSAHWNKLQLGVSYLLEDNHYSNN 176 V K ++ A + S Y S + L V Y L DN + Sbjct: 114 SVLKDTGDINPWDSKSDYLGVNKIAEPEARLISVRYDSPEFAGLSGSVQYALNDN--AGR 171 Query: 177 DNRRDNG---NYQ---LAVTYGDKFFKTSDVYAAVAYSDGVEDIEAYRGVIQYKWDKW-- 228 N NY+ V YG + + V V +E + +R V Y D Sbjct: 172 HNSESYHAGFNYKNGGFFVQYGGAYKRHHQVQENV----NIEKYQIHRLVSGYDNDALYA 227 Query: 229 QFATMLQHSQLVNTDKTDWQQREGDGVIVSAKYQLGQLSLNAQYGFDNSGTGLIANRIYA 288 A Q ++LV + + Q E V + Y+ G ++ Y G + Sbjct: 228 SVAVQQQDAKLVEENYSHNSQTE---VAATLAYRFGNVTPRVSY-----AHGFKGSFDAT 279 Query: 289 SKNTLIDEVPEISQWAIGAEYKLSKSTRLHTEIGQFDVKQY-DDFDDTIVSLGMRYDF 345 + N D+V +GAEY SK T G + F T +G+R+ F Sbjct: 280 NYNNDYDQV------VVGAEYDFSKRTSALVSAGWLQEGKGESKFVSTAGGVGLRHKF 331
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 31.7 bits (72), Expect = 0.012 Identities = 13/67 (19%), Positives = 26/67 (38%), Gaps = 6/67 (8%) Query: 121 GSVKEFSALNKPLWQAQLAKRGIEVEQELKKLFSSSAFINTIPAKVGAVVTLPAYQGHTN 180 + E + L G ++++E K+ A I+T +KV +V TN Sbjct: 330 AGIGENGPEIREFILDGLEFLGFKLDKEKNKVRGEEAIISTADSKVNVMVV------PTN 383 Query: 181 AKLTVLQ 187 + + + Sbjct: 384 EEYMIAK 390
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 38.2 bits (88), Expect = 3e-04 Identities = 28/88 (31%), Positives = 45/88 (51%), Gaps = 11/88 (12%) Query: 303 KRIVNDLLLALAHLCRNGVVHRNITPEHILMG-ADGQPRLIDFD-YARIGAENTTTIADE 360 K I + LL HL + GVVH +I P +++ A G+P +ID ++R G E Sbjct: 248 KFIAHRLLDVTNHLAKAGVVHNDIKPGNVVFDRASGEPVVIDLGLHSRSG---------E 298 Query: 361 VQQRISNRYKAPELWADSHAASCATDIY 388 + + +KAPEL + AS +D++ Sbjct: 299 QPKGFTESFKAPELGVGNLGASEKSDVF 326 Score = 32.0 bits (72), Expect = 0.022 Identities = 30/119 (25%), Positives = 54/119 (45%), Gaps = 18/119 (15%) Query: 544 LERLKQEYRTLVKLPEHPYVVKVYDADVLP--NQGPPYIVFEYLEGLDVSELI------- 594 LE K Y+T K HP + V+ V+P N+ ++ + ++G S+ + Sbjct: 177 LEAYKHIYKTAGK---HPNLANVHGMAVVPYGNRKEEALLMDEVDGWRCSDTLRTLADSW 233 Query: 595 QQRSLTAHEVWTMAKQVAEGL----QHLHEHNIFHCDIKPQNLMWK--DGKVRIIDFNV 647 +Q + + W K +A L HL + + H DIKP N+++ G+ +ID + Sbjct: 234 KQGKINSEAYWGTIKFIAHRLLDVTNHLAKAGVVHNDIKPGNVVFDRASGEPVVIDLGL 292
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 33.4 bits (76), Expect = 0.008 Identities = 20/85 (23%), Positives = 28/85 (32%), Gaps = 2/85 (2%) Query: 1141 PASQVQAPIQAAA-PVAVAVTKPVVPAQAPVVQGLAAEPKVTAVPVSEPTVQQPQVALAQ 1199 P VQ P + P P P +APVV P V+QP+ + Sbjct: 62 PPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPK-PKPVKKVEQPKRDVKP 120 Query: 1200 VAQTKVTQPPLAQPQVQTVAAQTSA 1224 V + P T + T+A Sbjct: 121 VESRPASPFENTAPARPTSSTATAA 145
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 28.4 bits (63), Expect = 0.016 Identities = 14/53 (26%), Positives = 25/53 (47%), Gaps = 3/53 (5%) Query: 138 IALAPNEQGKGLGHQLVQAVVSWCDEQPNLEGIGVFTTQE--AHTHLFKQHDF 188 IA+A + + KG+G L+ + W E G+ + T + H + +H F Sbjct: 95 IAVAKDYRKKGVGTALLHKAIEWAKENH-FCGLMLETQDINISACHFYAKHHF 146
>BCTLIPOCALIN#Bacterial lipocalin signature. Length = 171 Score = 254 bits (651), Expect = 4e-90 Identities = 112/171 (65%), Positives = 145/171 (84%) Query: 1 MKKLLLMISVLVLTGCLGMPNYVEPVKDFELDRYLGKWYEIARLDHSFERGLTQVTAEYS 60 M+ + L++ ++L GCLGMP V+PV DFEL+ YLGKWYE+ARLDHSFERGL+QVTAEY Sbjct: 1 MRAIFLILCSVLLNGCLGMPESVKPVSDFELNNYLGKWYEVARLDHSFERGLSQVTAEYR 60 Query: 61 LKPDGGVKVINRGYSAAKQQWKEAEGKAYFVNGENEAYLKVSFFGPFYGAYVVFGLDQQN 120 ++ DGG+ V+NRGYS K +WKEAEGKAYFVNG + YLKVSFFGPFYG+YVVF LD++N Sbjct: 61 VRNDGGISVLNRGYSEEKGEWKEAEGKAYFVNGSTDGYLKVSFFGPFYGSYVVFELDREN 120 Query: 121 YQYAFISGPDTDYLWLLARTPTVSPEVIQQFVDMAKAKGFDTDSLIYVEQK 171 Y YAF+SGP+T+YLWLL+RTPTV ++ +F++M+K +GFDT+ LIYV+Q+ Sbjct: 121 YSYAFVSGPNTEYLWLLSRTPTVERGILDKFIEMSKERGFDTNRLIYVQQQ 171
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 55.6 bits (134), Expect = 1e-10 Identities = 30/144 (20%), Positives = 49/144 (34%), Gaps = 9/144 (6%) Query: 49 TVERDRLTLTAPVGELIHKINVVEGQQVKAGEVLLELDSTAVNARLAQRQAELKQA---- 104 T + ++ +I V EG+ V+ G+VLL+L + A + Q+ L QA Sbjct: 91 THSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQ 150 Query: 105 ---QAKFDEAVTGARFEDIDKARAVLNGANASVKEAKQSFERTQR--LFKTKVLSQADLD 159 Q E + S + Q K + +LD Sbjct: 151 TRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLD 210 Query: 160 AARAAKDTSLAKQAEAEQSLRLLQ 183 RA + T LA+ E R+ + Sbjct: 211 KKRAERLTVLARINRYENLSRVEK 234 Score = 45.6 bits (108), Expect = 2e-07 Identities = 36/290 (12%), Positives = 87/290 (30%), Gaps = 46/290 (15%) Query: 71 VEGQQVKAGEVLLELDSTAVNARLAQRQAELKQAQAKFDEAVTGARFEDIDKARAVLNGA 130 V ++V L++ + + Q++ L + +A + A +N Sbjct: 179 VSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRA------------ERLTVLARINRY 226 Query: 131 NASVKEAKQSFERTQRLFKTKVLS--------------QADLDAARAAKDTSLAKQAEAE 176 + K + L + ++ +L ++ + ++ A+ Sbjct: 227 ENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAK 286 Query: 177 QSLRLLQNGTRSEQIEQARSAVDVAIAAVALEQKALKDLSLVAAKH----AVVDTLPWRV 232 + +L+ ++E +++ R D K + + V Sbjct: 287 EEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTE 346 Query: 233 GDRVAAGSQLIGLLAIERPF-VRLYLPATWLDRVKAGSHVDILVDG----RAAPIAGTVR 287 G V L+ ++ + V + + + G + I V+ R + G V+ Sbjct: 347 GGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVK 406 Query: 288 NI-----RSQPAYTPFYALNERDRARLMYLTDIDIAEEGQSLATGMPLEV 332 NI Q F + + L + L++GM + Sbjct: 407 NINLDAIEDQRLGLVFNVIISIEENCLS------TGNKNIPLSSGMAVTA 450
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 37.2 bits (86), Expect = 5e-05 Identities = 42/166 (25%), Positives = 77/166 (46%), Gaps = 23/166 (13%) Query: 186 GVILTMTMVMFT----SAAIVREREQGNMEFLITTPVRPLELMLGKI----TPYVLVGFV 237 G++ T M T AA R Q E ++ T +R +++LG++ T L G Sbjct: 72 GMVATSAMTAATFETIYAAFGRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAG 131 Query: 238 QVTIILSAGH-----LLFDVPIRGGIDSIAFAAMLFICASLTLGLVISTIAKTQLQSMQM 292 + + G+ LL+ +P+ IA + F +LG+V++ +A + + Sbjct: 132 IGVVAAALGYTQWLSLLYALPV------IALTGLAFA----SLGMVVTALAPSYDYFIFY 181 Query: 293 TVFILLPSILLSGFMFPYEAMPVAAQWIAEALPATHFMRMSRAIVL 338 ++ P + LSG +FP + +P+ Q A LP +H + + R I+L Sbjct: 182 QTLVITPILFLSGAVFPVDQLPIVFQTAARFLPLSHSIDLIRPIML 227
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.0 bits (70), Expect = 0.009 Identities = 14/70 (20%), Positives = 28/70 (40%), Gaps = 13/70 (18%) Query: 64 KLPTPHELRAHLDDYVIGQDRAKKVLSVAVYNHYKRLKNSSPKDGVELGKSNILLIGPTG 123 + P+ E + ++G+ A +Y RL + +++ G +G Sbjct: 124 RRPSKLEDDSQDGMPLVGRSAA----MQEIYRVLARLMQT---------DLTLMITGESG 170 Query: 124 SGKTLLAETL 133 +GK L+A L Sbjct: 171 TGKELVARAL 180
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 32.9 bits (75), Expect = 0.006 Identities = 40/211 (18%), Positives = 77/211 (36%), Gaps = 37/211 (17%) Query: 262 NMPSDAKEKAVAELNKLRMMSP---MSAEATV---VRSY----VDWMTSVPWSQRSKIKR 311 MP + + + K R P MSA+ T +++ D++ P+ I Sbjct: 56 VMPDENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPK-PFDLTELIGI 114 Query: 312 DLAKAQEVLDTDHYGLEKVKDRILEYLAVQSRVRQLKGPI---------LCLVGPPGVGK 362 +A LE + + + ++++ + L + G G GK Sbjct: 115 I-GRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGK 173 Query: 363 TSLGQSIAKATGRK---YVRVALGGVRD---EAEIRGHRRTYIGSMPGKVIQKMAKVGVK 416 + +++ R+ +V + + + E+E+ GH + G+ G + + Sbjct: 174 ELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEK---GAFTGAQTRSTGRFEQA 230 Query: 417 N--PLFLLDEIDKMSSDMRGDPASALLEVLD 445 LFL DEI M D + + LL VL Sbjct: 231 EGGTLFL-DEIGDMPMDAQ----TRLLRVLQ 256
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 119 bits (300), Expect = 4e-39 Identities = 53/88 (60%), Positives = 69/88 (78%) Query: 2 NKSELIEKIASGADISKAAAGRALDSFIAAVTEGLKEGDKISLVGFGTFEVRERAERTGR 61 NK +LI K+A +++K + A+D+ +AV+ L +G+K+ L+GFG FEVRERA R GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 62 NPQTGEEIKIAAAKIPAFKAGKALKDAV 89 NPQTGEEIKI A+K+PAFKAGKALKDAV Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAV 90
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 77.3 bits (190), Expect = 1e-17 Identities = 104/414 (25%), Positives = 164/414 (39%), Gaps = 51/414 (12%) Query: 1 MNKTIVATALAALFLAPTVSAIEIYKDDKNAVEIGGFIDARVINTQGETEVVNG-ASRIN 59 M + ++A + AL A A EIY D N +++ G +D + ++ +G + + Sbjct: 1 MKRKVLALVIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSDDSSK--DGDQTYMR 58 Query: 60 FGFSRE--LSDGWNAFAKLEWGVNPVGNSDIVYSNRFESVQDEFFYNRLGYAGLSHDKYG 117 GF E ++D + + E+ V +N E + RL +AGL YG Sbjct: 59 VGFKGETQINDQLTGYGQWEYNVQ---------ANTTEGEGANSW-TRLAFAGLKFGDYG 108 Query: 118 TLTIGKQWGAWYDVVYGTNYGFVWDGNTAGVYTFNKDDGAVNGVGRGDKTVQYRNT--FG 175 + G+ +G YDV T+ + G++ Y N G NGV YRNT FG Sbjct: 109 SFDYGRNYGVLYDVEGWTDMLPEFGGDSYT-YADNYMTGRANGV------ATYRNTDFFG 161 Query: 176 DV---SIAAQVQLKNSSFYTCDSVPDQDDCKK----LWETGDRSAQQVDYDETYGFAVTY 228 V + A Q Q KN S D ++ ++ GD YD GF+ Sbjct: 162 LVDGLNFALQYQGKNESQSADDVNIGTNNRNNGDDIRYDNGDGFGISTTYDIGMGFSAGA 221 Query: 229 KATDKLTLTAGVNRGEFDVSFGNGESTTAVDLIYGAGIMWGGFDANGWYAAA------NI 282 T VN G + G+ A + AG+ +DAN Y A N+ Sbjct: 222 AYTTSDRTNEQVNAG---GTIAGGDKADA----WTAGLK---YDANNIYLATMYSETRNM 271 Query: 283 NKQENHDTDNLGRLIKEAVGAETLLSYKFDNGLRYFVSYNILDAGKDYVIQPNLPIYAND 342 D G + + E Y+FD GLR VS+ ++ GKD + N+ D Sbjct: 272 TPYGKTDKGYDGGVANKTQNFEVTAQYQFDFGLRPAVSF-LMSKGKD-LTYNNVNGDDKD 329 Query: 343 VFKRQFVVAGVHYLMDANTVIYLEGRKDFSDFTGVDEAAMALSEDDGIAIGIRY 396 + K + G Y + N Y++ + + D +S DD +A+G+ Y Sbjct: 330 LVK--YADVGATYYFNKNFSTYVDYKINLLDDDDPFYKDAGISTDDIVALGMVY 381
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 662 bits (1709), Expect = 0.0 Identities = 257/1090 (23%), Positives = 471/1090 (43%), Gaps = 92/1090 (8%) Query: 7 SVKRPVTVWMFMLAIMLFGMVGFSRLAVKLLPDLSYPTLTIRTMYDGAAPVEVEQLVSKP 66 ++RP+ W+ + +M+ G + +L V P ++ P +++ Y GA V+ V++ Sbjct: 5 FIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQV 64 Query: 67 IEEAVGVVKGLRKISSISRS-GMSDVVLEFEWGTTMDMASLDVREKLDTI--ALPLDVKK 123 IE+ + + L +SS S S G + L F+ GT D+A + V+ KL LP +V++ Sbjct: 65 IEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQQ 124 Query: 124 PLLLRFNPNLDPIMRLALSVPNASEAELKQMRTYAEEELKRRLEALSGVAAVRLSGGLEQ 183 + + +M N + Y +K L L+GV V+L G + Sbjct: 125 QGISVEKSSSSYLMVAGFVSDNPGT-TQDDISDYVASNVKDTLSRLNGVGDVQLFGA-QY 182 Query: 184 EVHIQLNQEKLSQLNLNADDIKRRINEENINLSAGKVIQGD------REYLVRTLNQFNS 237 + I L+ + L++ L D+ ++ +N ++AG++ + +F + Sbjct: 183 AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKN 242 Query: 238 LDELGQVIVYRDAQ-TLVRLFEVATITDAYKERSDITRIGSQESIELAIYKEGDANTVAV 296 +E G+V + ++ ++VRL +VA + + + I RI + + L I AN + Sbjct: 243 PEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDT 302 Query: 297 AKKLRDELVKINKD-PQQNKLEVIYDQSEFIESAVSEVTSSALMGSVLAMLVIYLFLRNI 355 AK ++ +L ++ PQ K+ YD + F++ ++ EV + +L LV+YLFL+N+ Sbjct: 303 AKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNM 362 Query: 356 IPTLIISISIPFSVIATFNMMYFADISLNIMSLGGIALAIGLLVDNAIVVLENIDRC-RS 414 TLI +I++P ++ TF ++ S+N +++ G+ LAIGLLVD+AIVV+EN++R Sbjct: 363 RATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMME 422 Query: 415 EGMSKLDAAVTGTKEVAGAIFASTMTTLAVFVPLVFVDGIAGALFSDQALTVTFALLASL 474 + + +A ++ GA+ M AVF+P+ F G GA++ ++T+ A+ S+ Sbjct: 423 DKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSV 482 Query: 475 LVALTSIPMLASREGFKILPELMKKTPKEKPTTKLGKLKHYSATVFSFPIVLLFNYLPSA 534 LVAL P L + L+K E K Sbjct: 483 LVALILTPALCAT--------LLKPVSAEHHENK-------------------------- 508 Query: 535 LLTFVLIIGRFFSWLLGLIMRPLSSGFNFVYHSTESIYHKLLAIALRKQLATLLLTTGIT 594 G FF W FN + + + Y + L LL+ I Sbjct: 509 --------GGFFGW------------FNTTFDHSVNHYTNSVGKILGSTGRYLLIYALIV 548 Query: 595 GACISLLPRLGMELIPPMNQGEFYVEILLPPGTAVGETDRILQQLALSI--KDRPEVKHA 652 + L RL +P +QG F I LP G T ++L Q+ ++ V+ Sbjct: 549 AGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNEKANVESV 608 Query: 653 YSQAGSGGLMTSDTARGGENWGRLQVELVDHSAYHQVTQVLRDTARRIPALEAKIEQPEL 712 ++ G + +N G V L + R KI + Sbjct: 609 FTVNGFS------FSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGFV 662 Query: 713 FSFKTPLEIEL---TGYDLALLKRSADSLVNALSASDRFA-----------DINTSLRDG 758 F P +EL TG+D L+ ++ A ++ + + + Sbjct: 663 IPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLED 722 Query: 759 QPELSIRFDHARLAALGMDAPTVANRIAQRVGGTVASQYTVRDRKIDILVRSQLDERDQI 818 + + D + ALG+ + I+ +GGT + + R R + V++ R Sbjct: 723 TAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRMLP 782 Query: 819 SDIDTLIINPDSSQPIALSAVAEVSLQLGPSAINRISQQRVALVSANLAYGDLSDAVADA 878 D+D L + + + + SA G + R + + A G S Sbjct: 783 EDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMAL 842 Query: 879 QQILAAQVLPTSVQARFGGQNEEMEHSFQSLKIALILAVFLVYLVMASQFESLLHPLLIL 938 + LA++ LP + + G + + S + ++ +V+L +A+ +ES P+ ++ Sbjct: 843 MENLASK-LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVM 901 Query: 939 VAVPMALAGSVLGLYITQTHLSVVVFIGLIMLAGIVVNNAIVLVDRINQL-RSEGVEKLE 997 + VP+ + G +L + V +GL+ G+ NAI++V+ L EG +E Sbjct: 902 LVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVE 961 Query: 998 AIRVAAKSRLRPIMMTTLTTVLGLLPMALGLGDGAEVRAPMAITVIFGLSLSTLLTLIVI 1057 A +A + RLRPI+MT+L +LG+LP+A+ G G+ + + I V+ G+ +TLL + + Sbjct: 962 ATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFV 1021 Query: 1058 PVLYAMFDRK 1067 PV + + R Sbjct: 1022 PVFFVVIRRC 1031 Score = 114 bits (286), Expect = 1e-27 Identities = 95/520 (18%), Positives = 195/520 (37%), Gaps = 38/520 (7%) Query: 578 IALRKQLATLLLTTGITGACISLLPRLGMELIPPMNQGEFYVEILLPPGTAVGETDRILQ 637 +R+ + +L + A + +L + P + V P A D + Q Sbjct: 4 FFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQ 63 Query: 638 QLALSIKDRPEVKHAYSQAGSGGLMTSDTARGGENWGRLQVELVDHSAYHQVTQVLRDTA 697 + ++ + + S + S G +T L + QV Sbjct: 64 VIEQNMNGIDNLMYMSSTSDSAGSVTIT----------LTFQS-GTDPDIAQVQVQNKLQ 112 Query: 698 RRIPALEAKIEQPELFSFKTP----LEIELTGYDLALLKRS-----ADSLVNALSASDRF 748 P L +++Q + K+ + + + A ++ + LS + Sbjct: 113 LATPLLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGV 172 Query: 749 ADINTSLRDGQPELSIRFDHARLAALGMDAPTVANRI----AQRVGGTVASQYTVRDRKI 804 D+ Q + I D L + V N++ Q G + + +++ Sbjct: 173 GDVQLF--GAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQL 230 Query: 805 D--ILVRSQLDERDQISDIDTLIINPDSSQPIALSAVAEVSLQLGPSAIN-RISQQRVAL 861 + I+ +++ ++ + TL +N D S + L VA V L + RI+ + A Sbjct: 231 NASIIAQTRFKNPEEFGKV-TLRVNSDGS-VVRLKDVARVELGGENYNVIARINGKPAAG 288 Query: 862 VSANLAYGDLSDAVADA-QQILA--AQVLPTSVQA-RFGGQNEEMEHSFQSLKIALILAV 917 + LA G + A A + LA P ++ ++ S + L A+ Sbjct: 289 LGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAI 348 Query: 918 FLVYLVMASQFESLLHPLLILVAVPMALAGSVLGLYITQTHLSVVVFIGLIMLAGIVVNN 977 LV+LVM +++ L+ +AVP+ L G+ L ++ + G+++ G++V++ Sbjct: 349 MLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDD 408 Query: 978 AIVLVDRINQ-LRSEGVEKLEAIRVAAKSRLRPIMMTTLTTVLGLLPMALGLGDGAEVRA 1036 AIV+V+ + + + + + EA + ++ + +PMA G + Sbjct: 409 AIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYR 468 Query: 1037 PMAITVIFGLSLSTLLTLIVIPVLYAMF--DRKKFDHTNI 1074 +IT++ ++LS L+ LI+ P L A H N Sbjct: 469 QFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENK 508
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 47.1 bits (112), Expect = 6e-08 Identities = 30/195 (15%), Positives = 65/195 (33%), Gaps = 15/195 (7%) Query: 89 QSLAIIDAKRQQYDLDRSEAEVKIIEQELNRLKKMNNKEFISADSMAKLEYNLQAAIARR 148 + + Y + E +I+ + + D + + N+ Sbjct: 259 NKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLEL 318 Query: 149 DLAELQVKESHVVSPIDGIIAKRYVKAGNMAKEFGD-LFYIV-NQDELHGIVHLPEQQLT 206 E + + S + +P+ + + V + L IV D L + + + Sbjct: 319 AKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIG 378 Query: 207 SLRLGQEAQV-FS--NQQSKNAINAKVLRISP--VVDPQSGT-FKVTLAVP-------NQ 253 + +GQ A + + KV I+ + D + G F V +++ N+ Sbjct: 379 FINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCLSTGNK 438 Query: 254 DARLKAGMFTRVELK 268 + L +GM E+K Sbjct: 439 NIPLSSGMAVTAEIK 453 Score = 40.6 bits (95), Expect = 6e-06 Identities = 19/84 (22%), Positives = 34/84 (40%), Gaps = 9/84 (10%) Query: 37 PVETTTVIQGNVSSFYSTTATLEAPQEANVVSRIAGLIEVINVEEGDRVKKGQSLAIIDA 96 VE G ++ S + P E ++V I V+EG+ V+KG L + A Sbjct: 79 QVEIVATANGKLTH--SGRSKEIKPIENSIVKEII-------VKEGESVRKGDVLLKLTA 129 Query: 97 KRQQYDLDRSEAEVKIIEQELNRL 120 + D ++++ + E R Sbjct: 130 LGAEADTLKTQSSLLQARLEQTRY 153
>PF06580#Sensor histidine kinase Length = 349 Score = 34.5 bits (79), Expect = 7e-04 Identities = 19/102 (18%), Positives = 34/102 (33%), Gaps = 23/102 (22%) Query: 356 LMENAFRLCISQ------VQVTAHFNEQGDFELIVEDDGPGVEEQLRQKIIQRGVRADTQ 409 L+EN + I+Q + + + G L VE+ G + ++ Sbjct: 263 LVENGIKHGIAQLPQGGKILLKG-TKDNGTVTLEVENTGSLALKNTKE------------ 309 Query: 410 SPGQGIGLA-VCDEIVSSYGGSLKIE-ESHLEGALFRITIPA 449 G GL V + + YG +I+ + IP Sbjct: 310 --STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIPG 349
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 76.8 bits (189), Expect = 2e-18 Identities = 31/120 (25%), Positives = 57/120 (47%), Gaps = 1/120 (0%) Query: 2 RILVVEDDLILSHHLKVQLSDLGNQVQVALTAKEGFFQATNYPIDVAIVDLGLPDQDGIS 61 ILV +DD + L LS G V++ A + D+ + D+ +PD++ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 LIQQLREEGVKAPILILTARVNWQDKVEGLNAGADDYLVKPFQKEELVARLD-ALVRRSA 120 L+ ++++ P+L+++A+ + ++ GA DYL KPF EL+ + AL Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124
>INTIMIN#Intimin signature. Length = 939 Score = 45.4 bits (107), Expect = 1e-06 Identities = 57/290 (19%), Positives = 99/290 (34%), Gaps = 28/290 (9%) Query: 384 TTNISANQPAKVTVTL-VDKDSIPLSGKVVSFASSLGNFLPSKGTALTDSIGRASITLTA 442 T+ A+ +T T V K+ + + VSF G + S +A T+ G+A++TL + Sbjct: 567 KTSAKADGTEAITYTATVKKNGVAQANVPVSFNIVSGTAVLSANSANTNGSGKATVTLKS 626 Query: 443 GSIEGAGEITATYGTAKAIIGFATAGDEIDPVEASPEITFDIYNCNGVAAWDKTLKNFEV 502 G++ + TA + + A+ I D E+ Sbjct: 627 DKP---GQVVVSAKTA----------EMTSALNANAVIFVD----------QTKASITEI 663 Query: 503 CQPTDNITNDKPGIIGAKVTRSGSTQPLQQVLVTAATTLGAISPNSGTAITNADGKAILD 562 + I V +P+ VT TTLG ++ T T+ +G A + Sbjct: 664 KADKTTAVANGQDAITYTVKVMKGDKPVSNQEVTFTTTLGK--LSNSTEKTDTNGYAKVT 721 Query: 563 LYANGSVGAGEVSLKVKDVTSTKAFEIGRVNISLKLETSLGTNLLPAGGSTILDVTVLNP 622 L + + G VS +V DV +L ++ + + V + Sbjct: 722 LTST-TPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGTGVKGKLPTVWLQYG 780 Query: 623 DGSL-ATGQPFTLVFTSECQASNKAIIDSPVITNGGKGYATYRSTGCETQ 671 +L A+G + S A S +T KG T + Q Sbjct: 781 QVNLKASGGNGKYTWRSANPAIASVDASSGQVTLKEKGTTTISVISSDNQ 830 Score = 44.3 bits (104), Expect = 3e-06 Identities = 67/344 (19%), Positives = 126/344 (36%), Gaps = 39/344 (11%) Query: 55 ATPAEVKATVVDSKTGPKAGVVVTFKLDNASLGIFTPATGTQLTDSSGVATIKLETATLA 114 ATV + +A V V+F + + G + + T+ SG AT+ L++ Sbjct: 575 TEAITYTATVKKNGV-AQANVPVSFNIVS---GTAVLSANSANTNGSGKATVTLKSDKP- 629 Query: 115 GAGNVTASIATGESATKGFFSKGDGVTNPGTGNKLALSLVNQQQQVITGISAAVRGIIKA 174 G V+A A SA + T + + + + A+ +K Sbjct: 630 GQVVVSAKTAEMTSALNANAV----IFVDQTKASIT-EIKADKTTAVANGQDAITYTVKV 684 Query: 175 SYTNSLNEPLVGKVVVFNSTLGKLSPESGTALTNSQGIAEISITAGTIAGAGKITAKVDG 234 ++P+ + V F +TLGKLS + T T++ G A++++T+ T G ++A+V Sbjct: 685 MKG---DKPVSNQEVTFTTTLGKLS--NSTEKTDTNGYAKVTLTSTT-PGKSLVSARVSD 738 Query: 235 TEAEPLGFNTLGDEVVVKPIDSYAITLNIQDSQGNNLRKISHSVPGSVVATLLKDG---- 290 + V P + TL I N+ + V G + L+ G Sbjct: 739 VAVD-----------VKAPEVEFFTTLTI---DDGNIEIVGTGVKGKLPTVWLQYGQVNL 784 Query: 291 -VPASYQKISFNL--NGEGILNPSSGTALTDLSGRALVTLVTGTNAGAATVTASFSLDND 347 K ++ ++ SSG G +++++ N AT T + + ++ Sbjct: 785 KASGGNGKYTWRSANPAIASVDASSGQVTLKEKGTTTISVISSDNQ-TATYTIA-TPNSL 842 Query: 348 IITDSFNAEVAGDAPGGNGEANSLSIQLTNSLTGLSTTNISANQ 391 I+ + DA N L + +AN+ Sbjct: 843 IVPNMSKRVTYNDAVNTCKNFGGKLPSSQNELENVFKAWGAANK 886
>cdtoxinb#Cytolethal distending toxin B signature. Length = 269 Score = 27.7 bits (61), Expect = 0.037 Identities = 12/31 (38%), Positives = 18/31 (58%) Query: 131 GLPLPHMGWNQLTFSNPSQVHPLFAGVEAGS 161 G+P+ + WN T S P QV+ F+ V+A Sbjct: 81 GIPVRELIWNLSTNSRPQQVYIYFSAVDALG 111
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 63.3 bits (154), Expect = 9e-13 Identities = 26/122 (21%), Positives = 52/122 (42%) Query: 11 ILIVDNDAIASQSISDFIHGKGYNVIICDNLEDAFFEVSLNKIDLILVNYFQPDGTALTL 70 IL+ D+DA ++ + GY+V I N + ++ DL++ + PD A L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 71 LAHLDSLSKEIPVVVINDKKEPQAFLDCFKMGVLDFIVKPINVEVFWYKAEILLTRIKLQ 130 L + ++PV+V++ + + + G D++ KP ++ L K + Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRR 125 Query: 131 RK 132 Sbjct: 126 PS 127
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 86.8 bits (215), Expect = 2e-23 Identities = 30/122 (24%), Positives = 56/122 (45%), Gaps = 3/122 (2%) Query: 1 MSK-KILIVDDSAAIRQMVEATLKSANYQVTLAKDGREALDLCSSQRFDFILTDQNMPRM 59 M+ IL+ DD AAIR ++ L A Y V + + ++ D ++TD MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 60 DGLTLIKSLRGMSAFMRTPIIMLTTEAGDDMKAQGKAVGATGWMVKPFDPQKLLAITAKV 119 + L+ ++ A P+++++ + + GA ++ KPFD +L+ I + Sbjct: 61 NAFDLLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 120 LG 121 L Sbjct: 119 LA 120
>PF06580#Sensor histidine kinase Length = 349 Score = 35.2 bits (81), Expect = 8e-04 Identities = 13/66 (19%), Positives = 31/66 (46%), Gaps = 10/66 (15%) Query: 418 EIDKGMIEKLVDPLT--HLVRNSLDHGIEKPEVRRLLGKAEIAQLSLRASQRGGNIVIAV 475 +I+ +++ V P+ LV N + HGI + + ++ L+ ++ G + + V Sbjct: 245 QINPAIMDVQVPPMLVQTLVENGIKHGIAQ--------LPQGGKILLKGTKDNGTVTLEV 296 Query: 476 HDDGAG 481 + G+ Sbjct: 297 ENTGSL 302
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 99 bits (249), Expect = 5e-28 Identities = 30/115 (26%), Positives = 56/115 (48%), Gaps = 2/115 (1%) Query: 3 KILVVDDSASIRHVVSIALRGAGYEVIDACDGKDALSKLNGDKINLIISDVNMPNMDGIS 62 ILV DD A+IR V++ AL AGY+V + + +L+++DV MP+ + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 63 FLKEVKKHPRYKFTPVIMLTTEAGRDKMEEGRMAGAKAWVVKPFQPPQMLDAVAK 117 L +KK PV++++ + + GA ++ KPF +++ + + Sbjct: 65 LLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 34.8 bits (80), Expect = 9e-04 Identities = 22/109 (20%), Positives = 42/109 (38%), Gaps = 1/109 (0%) Query: 343 GDLTIELKQREQAT-GVYKAMIDMIDSLTSVIAQVRSGADNLSSASSQVSSTAQSLSQGA 401 G TI + GVY+A ++ ++ +I++VR + + + Q QGA Sbjct: 51 GGTTIRTESTTAIDVGVYRAALEPLELGDVIISEVRDPSFREDQHVAMIRIQMQEDGQGA 110 Query: 402 TEQAASVEETTSAVEELNASVQQNSENARVTNNMATVAAEEARQGGIAV 450 Q A +E + VE +V + + V+ E ++ Sbjct: 111 EGQGAQGQELVNKVETALTAVDPALKITSFESVGPKVSGELVWTAVWSL 159
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 47.9 bits (114), Expect = 6e-08 Identities = 23/90 (25%), Positives = 38/90 (42%), Gaps = 9/90 (10%) Query: 28 KILLVDDEPDVHTVTKLALSRFKLDGRALSFINAYSAEQAKEFLINEQDLAIAFIDVVME 87 IL+ DD+ + TV ALSR D R +A I D + DVVM Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRI-----TSNAATLWR-WIAAGDGDLVVTDVVMP 58 Query: 88 TDHAGLELVKWIREDHKNKTIRLILRTGQP 117 D +L+ I++ + + +++ + Q Sbjct: 59 -DENAFDLLPRIKKARPD--LPVLVMSAQN 85
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 67.2 bits (164), Expect = 3e-14 Identities = 77/388 (19%), Positives = 140/388 (36%), Gaps = 51/388 (13%) Query: 10 NMKFFIFLLYLALLSMLGFIATDMYLPAFKAIESSLNSSPSQVAMSLTCFLAGLALGQLI 69 N++ L++L +LS + + + I + N P+ T F+ ++G + Sbjct: 9 NLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAV 68 Query: 70 YGPLVSKLGKRYALLIGLAVFALSSVAIANSDSVMMLNI-ARFFQAIGACSAGVIWQAIV 128 YG L +LG + LL G+ + SV S L I ARF Q GA + + +V Sbjct: 69 YGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVV 128 Query: 129 VEQYDAEKAQGIFSNIMPLVALSPALAPILGAYILNEFGWRAIFISLCVIAFLLVLMTLY 188 E F I +VA+ + P +G I + W + + + +I + V + Sbjct: 129 ARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLL-IPMITIITVPFLMK 187 Query: 189 FVPGKSKHQD----------------------------IKPSAVSYG------------- 207 + + + + + S +S+ Sbjct: 188 LLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPF 247 Query: 208 ---QILKNTRYLGNVVIFGACSGAFFAYLTVWPIVMEQ-HGYQATEIGLSFI-PQTIMFI 262 + KN ++ V+ G G ++++ P +M+ H EIG I P T+ I Sbjct: 248 VDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVI 307 Query: 263 VGGYASKLLIKRIGADKTLNVLLSIFGICVVSIVLFTLLFKTITIFPLLISFSILAAANG 322 + GY +L+ R G LN+ ++ + ++ ++ L+ Sbjct: 308 IFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKT 367 Query: 323 AIYPIVVNSALQQFTQHASKAAGLQNFL 350 I IV +S Q Q A L NF Sbjct: 368 VISTIVSSSLKQ---QEAGAGMSLLNFT 392
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 37.0 bits (85), Expect = 3e-04 Identities = 20/77 (25%), Positives = 33/77 (42%), Gaps = 9/77 (11%) Query: 594 ALEEAKIQQMIAEQEAIAAQTKAAEEATLAKAKAEEKAEVERQRLDQQAQM----KAKQS 649 + ++ Q E QT +E A + EEKA+VE ++ + ++ KQ Sbjct: 1079 NTQTNEVAQS--GSETKETQTTETKET--ATVEKEEKAKVETEKTQEVPKVTSQVSPKQE 1134 Query: 650 QSEHE-PQDAIDRSDET 665 QSE PQ R ++ Sbjct: 1135 QSETVQPQAEPARENDP 1151
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 49.1 bits (117), Expect = 2e-08 Identities = 32/155 (20%), Positives = 63/155 (40%), Gaps = 12/155 (7%) Query: 4 VLFVDDDSFMLRALLRLAKRLRPEWQ-FWTEEDGLNWAKSIPHNVNIDLIVCDYLMPDIN 62 +L DDD+ + L + R + + W + DL+V D +MPD N Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGD----GDLVVTDVVMPDEN 61 Query: 63 GDSVLIEASKHFPLAIRALLTGDTTEEVVCKAGKA-AHFVLSKPFNEQDIVQLL-TCIER 120 +L K P +++ T KA + A+ L KPF+ +++ ++ + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 121 IHKLPFTHEVRA-----MLGASALLLPLPDIVQRV 150 + P E + ++G SA + + ++ R+ Sbjct: 122 PKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARL 156
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 102 bits (256), Expect = 4e-25 Identities = 39/134 (29%), Positives = 64/134 (47%), Gaps = 2/134 (1%) Query: 1 MDK-SLLLVDDDVGILKALTRLLTRSGYSVKTAQSGEEALTLLLNYDCKVVLTDFRMPYM 59 M ++L+ DDD I L + L+R+GY V+ + + D +V+TD MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 60 DGGQLLSKIKRLYPDIVSLVISGYSDFESVKSLLNAGSAYRFLQKPWEDDELLGEIANAF 119 + LL +IK+ PD+ LV+S + F + G AY +L KP++ EL+G I A Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKG-AYDYLPKPFDLTELIGIIGRAL 119 Query: 120 THYAKHLFQHQSQK 133 + + + Sbjct: 120 AEPKRRPSKLEDDS 133
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 88.7 bits (220), Expect = 5e-23 Identities = 28/116 (24%), Positives = 58/116 (50%), Gaps = 3/116 (2%) Query: 73 DKKSILIIDDELSMRNALRRALQSTPFTILTAQDGFQAGVKVIAEKPDLILLDLSLPGLD 132 +IL+ DD+ ++R L +AL + + + + A DL++ D+ +P + Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 133 GFEVIQFIRQRPDLAKLKILVLSGLSSIELA-ESIRLGADDAIAKPFDNHDLLDRV 187 F+++ I++ L +LV+S ++ A ++ GA D + KPFD +L+ + Sbjct: 62 AFDLLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGII 115
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 88.0 bits (218), Expect = 6e-21 Identities = 31/159 (19%), Positives = 67/159 (42%), Gaps = 5/159 (3%) Query: 12 ILCVDDEASILKSLQRLFIGKDLQILLADSGSKALELMLEHRVNVIITDMRMPNMTGAEF 71 IL DD+A+I L + + + + + + ++++TD+ MP+ + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 72 LAKAAILQPDAYRILMTGYADLASTVSAINLGKIHRYVQKPWDNQELLTVVDEGLALCHL 131 L + +PD ++M+ + + A G + Y+ KP+D EL+ ++ AL Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKG-AYDYLPKPFDLTELIGIIGR--ALAEP 122 Query: 132 IRQNKQLTAKVATQNKQLKELNSSLEETVLKRTEQLKQT 170 R+ +L + S+ + + + +L QT Sbjct: 123 KRRPSKLEDDSQDGMPLVGR--SAAMQEIYRVLARLMQT 159
>PF06580#Sensor histidine kinase Length = 349 Score = 35.6 bits (82), Expect = 4e-04 Identities = 31/180 (17%), Positives = 69/180 (38%), Gaps = 28/180 (15%) Query: 283 LAGARRARDIIKNL-----RNFSHPDENTISTINILELITDTVRIANTQVKKHARIKINH 337 L +AR+++ +L + + + +S + L ++ +++A ++ R++ + Sbjct: 187 LEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLA--SIQFEDRLQFEN 244 Query: 338 DLHHAFTQGNATQLSQVILNLINNA-HHSIKH--QHGLIEISINKFNNWINIEIEDNGCG 394 ++ A + ++ L+ N H I Q G I + K N + +E+E+ G Sbjct: 245 QINPAI--MDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSL 302 Query: 395 IDDTDIPHIFEPFFTTKEIGQGTGLGLSISRAIIEQHNGCIALVHTGLK--GTKFVISLP 452 K + TG GL R ++ G A + K ++ +P Sbjct: 303 A--------------LKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 67.2 bits (164), Expect = 2e-13 Identities = 26/112 (23%), Positives = 45/112 (40%), Gaps = 2/112 (1%) Query: 807 HVLIVDDVEDIRELIDIYLKDTEIAVDFAQNGQQAIQLVEKSHYDLVILDQQMPIMDGFT 866 +L+ DD IR +++ L V N + + DLV+ D MP + F Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 867 AAKAIREFNKSIPLLLLSA--DILDTEPHQKSPFNKTIAKPFTKNQLIETIR 916 I++ +P+L++SA + + + KPF +LI I Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>PF06580#Sensor histidine kinase Length = 349 Score = 29.1 bits (65), Expect = 0.038 Identities = 19/96 (19%), Positives = 34/96 (35%), Gaps = 17/96 (17%) Query: 327 NLLVNAAQAIEERGEISIDVSASDAEFIIVIRDTGSGIAASDLRKIFEPFYTTKLVGTGT 386 N + + + + G+I + + + + + +TGS K T Sbjct: 266 NGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLAL--------------KNTKEST 311 Query: 387 GLGLSLSYSIVQKHKGE---IKVSSVLGEGTAFTVI 419 G GL +Q G IK+S G+ A +I Sbjct: 312 GTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLI 347
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 61.4 bits (149), Expect = 3e-14 Identities = 24/112 (21%), Positives = 48/112 (42%), Gaps = 5/112 (4%) Query: 5 VTIADDSLMSRKAVRRALPEDWDVEITEACNGKEALEAANSGKAEVLFLDLTMPELDGFG 64 + +ADD R + +AL ++ N +G +++ D+ MP+ + F Sbjct: 6 ILVADDDAAIRTVLNQAL-SRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 65 VLKYLHEQQSKTVVIVISADIQPEAKLLVDSL--GAFRFLQKPLQPAQLREA 114 +L + + + V+V+SA Q + + GA+ +L KP +L Sbjct: 65 LLPRIKKARPDLPVLVMSA--QNTFMTAIKASEKGAYDYLPKPFDLTELIGI 114
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 27.4 bits (61), Expect = 0.048 Identities = 9/36 (25%), Positives = 14/36 (38%), Gaps = 1/36 (2%) Query: 109 NAKLVIHNPAPHAISLRYHSG-MTADLVLTTEQGQR 143 + +V+ NP AI + Y G LV + Sbjct: 256 RSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQ 291
>TACYTOLYSIN#Bacterial thiol-activated pore-forming cytolysin signature. Length = 574 Score = 26.1 bits (57), Expect = 0.036 Identities = 17/76 (22%), Positives = 37/76 (48%), Gaps = 3/76 (3%) Query: 14 LDEYGYEKKASTDLEQA--RNKQQMGKYIKSLDYSLRRLLILQ-ETVNELVEEKKHQLSQ 70 L+ E+K S D +++ + +++ I SL+Y+ +L ET+ V ++ + + Sbjct: 88 LESAEKEEKKSEDNKKSEEDHTEEINDKIYSLNYNELEVLAKNGETIENFVPKEGVKKAD 147 Query: 71 QENIQTYKTKIINLSR 86 + + K K IN + Sbjct: 148 KFIVIERKKKNINTTP 163
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 303 bits (778), Expect = 1e-95 Identities = 111/418 (26%), Positives = 187/418 (44%), Gaps = 65/418 (15%) Query: 384 QPGDVLVTDMTDPDWEPIMK-RASAIVTNRGGRTCHAAIIARELGVPAVVGCGDVTDRIK 442 + ++ D+T D + K T+ GGRT H+AI++R L +PAVVG +VT++I+ Sbjct: 155 EETVIIAEDLTPSDTAQLNKQFVKGFATDIGGRTSHSAIMSRSLEIPAVVGTKEVTEKIQ 214 Query: 443 NGQWVTVSCAEG---------DTGFIYEGKQEFEVVSNRVDALPALP--------MKIMM 485 +G V V EG + E + FE L P +++ Sbjct: 215 HGDMVIVDGIEGIVIVNPTEEEVKAYEEKRAAFEKQKQEWAKLVGEPSTTKDGAHVELAA 274 Query: 486 NVGNPDRAFDFARLPNEGVGLARLEFIINRMIGIHPKALLEFNQQDAALQEEINEMIAGY 545 N+G P EG+GL R EF+ + +D EE E Y Sbjct: 275 NIGTPKDVDGVLANGGEGIGLYRTEFL--------------YMDRDQLPTEE--EQFEAY 318 Query: 546 DSPVEFYIARLVEGIASIGSAFYPKKVIVRMSDFKSNEYANLVGGDRYEPEEENPMLGFR 605 V+ K V++R D ++ + + P+E NP LGFR Sbjct: 319 KEVVQ---------------RMDGKPVVIRTLDIGGDKELSYL----QLPKELNPFLGFR 359 Query: 606 GASRYISESFRDCFALECEAIKRVRNEMGLKNVEVMIPFVRTVKEAEQVIELLKEQGLER 665 + + +D F + A+ R N++VM P + T++E Q +++E+ + Sbjct: 360 AIRLCLEK--QDIFRTQLRALLRAS---TYGNLKVMFPMIATLEELRQAKAIMQEEKDKL 414 Query: 666 GKDG------LRVIMMCEVPSNALLADQFLEHFDGFSIGSNDLTQLTLGLDRDSGIISHL 719 +G + V +M E+PS A+ A+ F + D FSIG+NDL Q T+ DR + +S+L Sbjct: 415 LSEGVDVSDSIEVGIMVEIPSTAVAANLFAKEVDFFSIGTNDLIQYTMAADRMNERVSYL 474 Query: 720 FDERNEAVKILLSMAIKAAKAKGAYIGICGQGPSDHADFAAWLVEQGIDTVSLNPDTV 777 + + A+ L+ M IKAA ++G ++G+CG+ D L+ G+D S++ ++ Sbjct: 475 YQPYHPAILRLVDMVIKAAHSEGKWVGMCGEMAGDE-VAIPLLLGLGLDEFSMSATSI 531
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 28.7 bits (64), Expect = 0.007 Identities = 21/97 (21%), Positives = 41/97 (42%), Gaps = 21/97 (21%) Query: 15 AIEQRINQSEARVIKAVFPSITNHHNTLFGGEALAWMDETAFIAATRFCRKTLVTVSSDR 74 +E + A+V+ P++ N +A+ ET + V V+ Sbjct: 350 LLEN---EGSAQVVSR--PTLLTQENA----QAVIDHSETYY-----------VKVTGKE 389 Query: 75 IDFKKPIPAGTLAELIARVIHVGNTSLKVEVNIFVED 111 + K I GT+ + RV+ G+ S ++ +N+ +ED Sbjct: 390 VAELKGITYGTMLRMTPRVLTQGDKS-EISLNLHIED 425
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 77.2 bits (190), Expect = 1e-18 Identities = 34/110 (30%), Positives = 51/110 (46%), Gaps = 4/110 (3%) Query: 8 IIIADDHPLFRNALRQALSSAFEHTQWFEADSADALQSVLDSPTVSYDLVLLDLQMPGSH 67 I++ADD R L QALS A +A L + + DLV+ D+ MP + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDV--RITSNAATLWRWIAA--GDGDLVVTDVVMPDEN 61 Query: 68 GYSTLIHLRSHYPDLPVIVISAHEDINTISRAIHYGGSGFIPKSASMETL 117 + L ++ PDLPV+V+SA T +A G ++PK + L Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTEL 111
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.001 Identities = 12/43 (27%), Positives = 18/43 (41%), Gaps = 4/43 (9%) Query: 1 MERFDRDWHKADIKAALEKAGTNYEKLAEEHGIAGSTLRNALR 43 + + I AAL N K A+ G+ +TLR +R Sbjct: 433 LAEMEYPL----ILAALTATRGNQIKAADLLGLNRNTLRKKIR 471
>FIMREGULATRY#Escherichia coli: P pili regulatory PapB protein signature. Length = 104 Score = 29.9 bits (67), Expect = 6e-04 Identities = 15/62 (24%), Positives = 27/62 (43%) Query: 4 LLRGAESPERITLMLKMTGIRSPEIIAAIYEHLQFGMREKHAAIKHGVEQQNLNRALNTL 63 LL G+ S L++ ++ I S +I A+ ++L G K K+ + + L L Sbjct: 23 LLPGSMSEMHFFLLIGISSIHSDRVILAMKDYLVGGHSRKEVCEKYQMNNGYFSTTLGRL 82 Query: 64 NE 65 Sbjct: 83 IR 84
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 33.5 bits (76), Expect = 7e-04 Identities = 18/84 (21%), Positives = 32/84 (38%), Gaps = 7/84 (8%) Query: 33 QTQKTESQTVVNSDADKATADAEAKAKLEADTLA------KEQAEQAAKQAAEQQAKDEA 86 +T + Q + A EAK+ ++A+T + ++ ++ A E Sbjct: 1049 KTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEK 1108 Query: 87 EAKAKADEQDKLNPTNQDGSNEKP 110 E KAK E +K + S P Sbjct: 1109 EEKAKV-ETEKTQEVPKVTSQVSP 1131 Score = 28.5 bits (63), Expect = 0.022 Identities = 21/120 (17%), Positives = 47/120 (39%), Gaps = 8/120 (6%) Query: 2 SEPQAKTQTRSRKNAGQSVSTTATVAQDPLLQTQKTESQTVVNSDADKATADAEAKAKLE 61 + Q + + K+ ++ + T VAQ ++ E+QT + + +AK + E Sbjct: 1061 TTAQNREVAKEAKSNVKANTQTNEVAQ---SGSETKETQTTETKETATVEKEEKAKVETE 1117 Query: 62 -----ADTLAKEQAEQAAKQAAEQQAKDEAEAKAKADEQDKLNPTNQDGSNEKPLSKNPS 116 ++ +Q + + QA+ E + ++ + TN E+P + S Sbjct: 1118 KTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSS 1177
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 25.2 bits (55), Expect = 0.035 Identities = 13/48 (27%), Positives = 18/48 (37%), Gaps = 5/48 (10%) Query: 34 GADSLDTVELVMALEEEFDTEIPDEEAEKIT-----TVQAAIDYVSKN 76 GA++LDT + + A E P VQ +I V K Sbjct: 296 GANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKT 343
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 142 bits (358), Expect = 1e-43 Identities = 82/251 (32%), Positives = 131/251 (52%), Gaps = 13/251 (5%) Query: 7 LAGKVALVTGASRGIGRAIAETLVEAGAVVIGTATSEKGAAAIQEYLGDKGF---GLVLN 63 + GK+A +TGA++GIG A+A TL GA + + + + L + + Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 64 VTDSQSVTDLFDSIKEKAGDVDILVNNAGITRDNLLMRMKDDEWNDIIDTNLTSLFRLSK 123 V DS ++ ++ I+ + G +DILVN AG+ R L+ + D+EW N T +F S+ Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 124 PVMRTMMKKRFGRIINIGSVVGTMGNAGQVNYSAAKAGLIGFTKSLAREVASRQITVNAI 183 V + MM +R G I+ +GS + Y+++KA + FTK L E+A I N + Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 184 APGFIQTDM-----TDELTEDQQ-KAIMSQ----VPMERLGQAQEIANAVLFLASDSAAY 233 +PG +TDM DE +Q K + +P+++L + +IA+AVLFL S A + Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGH 245 Query: 234 ITGETLHVNGG 244 IT L V+GG Sbjct: 246 ITMHNLCVDGG 256
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 129 bits (326), Expect = 9e-39 Identities = 85/257 (33%), Positives = 130/257 (50%), Gaps = 15/257 (5%) Query: 3 SSNNLQGKVAFVQGGSRGIGAAIVKRLASEGAAVAFTYVSSEAQSQLLVDEVIAQGGKAI 62 ++ ++GK+AF+ G ++GIG A+ + LAS+GA +A + E + +V + A+ A Sbjct: 2 NAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKL-EKVVSSLKAEARHAE 60 Query: 63 AIKADSTEPEAIRRAIRETKAHLGGLDIVVNNAGILIWDSIENLTLEDWERIVNTNVRSV 122 A AD + AI + +G +DI+VN AG+L I +L+ E+WE + N V Sbjct: 61 AFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGV 120 Query: 123 FVASQEAALHMND--GGRIINIGSTNAERIPFVGGAIYGMSKSALVGLAKGLARDLGPRA 180 F AS+ + +M D G I+ +GS N +P A Y SK+A V K L +L Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGS-NPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYN 179 Query: 181 ITVNNIQPGPVDTDMN-----PDNGD------SSEPIKAIGVLGRYGKAEEIASFVAFIA 229 I N + PG +TDM +NG S E K L + K +IA V F+ Sbjct: 180 IRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLV 239 Query: 230 GPEAGYITGASLMIDGG 246 +AG+IT +L +DGG Sbjct: 240 SGQAGHITMHNLCVDGG 256
>CABNDNGRPT#NodO calcium binding signature. Length = 479 Score = 33.0 bits (75), Expect = 0.002 Identities = 18/51 (35%), Positives = 22/51 (43%), Gaps = 6/51 (11%) Query: 78 GNDQFTRGDKIDRPQGGSG-----GGAGKGDASDSGEGNDDFVFEISKDEY 123 GND + QGG+G GGAG D G G D FV+ +D Sbjct: 348 GNDILVGNSADNILQGGAGNDVLYGGAG-ADTLYGGAGRDTFVYGSGQDST 397
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.3 bits (71), Expect = 0.018 Identities = 9/88 (10%), Positives = 39/88 (44%), Gaps = 8/88 (9%) Query: 601 RQEKEQEKLLQYQLNQLKD-------QQHKTQLAQQEIAQLRAQLTDANDEIN-LQTQLN 652 + + ++ + +L+ +H + + + +L ++ +++++ Sbjct: 224 NRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEIL 283 Query: 653 RNKQQSQKLMQHFLSDVMNQMMQEQDRL 680 K++ Q + Q F +++++++ Q D + Sbjct: 284 SAKEEYQLVTQLFKNEILDKLRQTTDNI 311
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 35.8 bits (82), Expect = 0.001 Identities = 33/217 (15%), Positives = 59/217 (27%), Gaps = 7/217 (3%) Query: 1002 ADEALAKSIETVAATIDKNAAAIITEQMARATADESLAKQIISISATVNGNAALIKQEQT 1061 K TV T+++ + T+ S KQ S + A Sbjct: 1095 TQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVS-PKQEQSETVQPQAEPARENDPTV 1153 Query: 1062 ARADADSALGQRIDTVQA---TTGANTAAIQQEQTARANADSALGQRIDTVQATTGANTA 1118 + S DT Q T+ + + T T T + Sbjct: 1154 NIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNS 1213 Query: 1119 AIQQEQTARANADSALGQRIDTVQATTGANTAAIQQEQTARANADSALGQRIDTVQATAG 1178 + R T+ + + + N ++ L Q A Sbjct: 1214 ESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVAL 1273 Query: 1179 ANTAAVQQTSTALAELDGKLQAMYSIKVGVTADGKYY 1215 AV Q +++L+ + Y++ V T+ K Y Sbjct: 1274 NVGKAVSQ---HISQLEMNNEGQYNVWVSNTSMNKNY 1307
>PF07520#Virulence protein SrfB Length = 1041 Score = 28.8 bits (64), Expect = 0.023 Identities = 20/74 (27%), Positives = 27/74 (36%), Gaps = 14/74 (18%) Query: 72 PDASSKPSD---RDRAMCEASGLPWHILSWPDGDLRTIVPTGERKSLLNRPFVHGVWDCY 128 P A+S R R + A L +L DG V +P + WD Sbjct: 503 PTATSVQEQAMIRSR-VSGALTLVKEMLGTKDGTSTIAVEG--------KPELLVDWDEA 553 Query: 129 SCVR--DWYSEVQQ 140 SC + YSE+ Q Sbjct: 554 SCTQLVYLYSELTQ 567
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 32.8 bits (74), Expect = 0.006 Identities = 43/205 (20%), Positives = 92/205 (44%), Gaps = 21/205 (10%) Query: 400 EELKALEAERDSVMALMKTERDRSAEQAKRAKLNQDSIEAQRAIAKVTEETLTNEQKRNK 459 E+ KALE E+++ K ++D+ ++ + N+ ++E A + L+N + ++ Sbjct: 143 EQKKALEKEKEAKEQAQKAQKDKREKRKEERAKNRANLE-NLTNAMSNPQNLSNNKNLSE 201 Query: 460 AIKEYNDN-------IEKVRKADPNSALLNADKIKRDLA--SIEEKFKDSAKTTKAFADD 510 IK+ +N +E +++ +AL +++ + A ++ ++ KD + Sbjct: 202 LIKQQRENELDQMERLEDMQEQAQANALKQIEELNKKQAEEAVRQRAKDKISIKTDKSQK 261 Query: 511 AATSYLMRLRETQAGLQGQLDRNTKLTQSQKELLQFEQQIADIKNKDVLTAQQKSLLAEQ 570 + + L + + + L + ++ K L QF I I KD + ++ E Sbjct: 262 SPEDNSIELSPSDSAWRTNL-----VVRTNKALYQF---ILRIAQKDNFASAYLTVKLEY 313 Query: 571 SVIRAQLEKNVALDEELKKRNEALR 595 + E + ++EELKKR EA R Sbjct: 314 P---QRHEVSSVIEEELKKREEAKR 335
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 27.3 bits (60), Expect = 0.010 Identities = 11/54 (20%), Positives = 23/54 (42%) Query: 41 LVELAPEQATEADAKADAEAKEKEEADAKAAAEAKEKEEADAKAAAAAAKKAKA 94 V +Q ++ K + +A E + + A EAK +A+ + A ++ Sbjct: 1039 TVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSET 1092
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 28.9 bits (64), Expect = 0.039 Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 1/59 (1%) Query: 22 DQIKSAAEETNKQIKASGEMHAETRDKVDKLLSEQGALQARLQEAEQKLLKGAQSNQQE 80 Q++ A EE N ++ A +++ E + E+ LQA+L EAE K LK + Q E Sbjct: 396 KQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKL-EAEAKALKEKLAKQAE 453
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 28.5 bits (63), Expect = 0.006 Identities = 16/42 (38%), Positives = 24/42 (57%), Gaps = 1/42 (2%) Query: 6 VIFNGKIVSVP-AVESYIDNGEKKLVPLVPADWVEVTALNAA 46 V +NGK+++ P AVE+ K L+P P W E+ AL+ Sbjct: 123 VRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKE 164
>CHLAMIDIAOMP#Chlamydia major outer membrane protein signature. Length = 393 Score = 30.0 bits (67), Expect = 0.004 Identities = 9/25 (36%), Positives = 17/25 (68%) Query: 83 SLPNVELNQASYDLYIDWTYQYGIG 107 S+PN+ L+Q+ +LY D + + +G Sbjct: 172 SVPNMSLDQSVVELYTDTAFSWSVG 196
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 26.7 bits (59), Expect = 0.010 Identities = 7/15 (46%), Positives = 12/15 (80%) Query: 5 VKCGSSSIEFQFVED 19 + CGSSS+++Q +E Sbjct: 6 INCGSSSLKYQLIES 20
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 28.6 bits (64), Expect = 0.001 Identities = 9/32 (28%), Positives = 17/32 (53%), Gaps = 5/32 (15%) Query: 15 HIKAALSVRQ--PTLTF---TGKCHYCKAPVS 41 H ++ + P L++ G+C C+AP+S Sbjct: 76 HCNHPITALENIPLLSWLWLRGRCRGCQAPIS 107
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 28.3 bits (63), Expect = 0.012 Identities = 22/93 (23%), Positives = 35/93 (37%), Gaps = 15/93 (16%) Query: 1 MKLITASLLLALLTGCATSAVTIDKAKPAPAERV-----LIGNTDSADAKITIIRDSGFM 55 K A + L CA +A P + + + + A A ++ + + Sbjct: 19 RKHRLAGFFVRLFVACAFAA-----QAPLSSAELYFNPRFLADDPQAVADLSRFENGQEL 73 Query: 56 GGGCY-VDVYVNDALAAKLDTAEKVTFNVRSGE 87 G Y VD+Y+N+ A D VTFN E Sbjct: 74 PPGTYRVDIYLNNGYMATRD----VTFNTGDSE 102
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 41.7 bits (98), Expect = 4e-06 Identities = 60/352 (17%), Positives = 112/352 (31%), Gaps = 40/352 (11%) Query: 47 GFLLAILMATRIVAPNVWAKVADRTGMRSELIKMGAGAAMLAYLSFFYHGGFVYMALSLA 106 G LLA+ + V ++DR G R L+ AGAA+ + MA + Sbjct: 46 GILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAI----------MATAPF 95 Query: 107 LYTFFWNAILAQLEVITLETLGENASRYGQIRSFGS----IGYICLVVGAGF----AIGQ 158 L+ + I+A IT T + I G++ G G +G Sbjct: 96 LWVLYIGRIVAG---ITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGG 152 Query: 159 WGTEVLPYIGLVLFTGMLVCALPLPANRAVRPQGQERQPLKWT--------------KPI 204 P+ + ER+PL+ + Sbjct: 153 LMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVV 212 Query: 205 IWFMISAMLLQMSAGPFYGFFVLYLKQA-GYTEAAAGI-FVALGAMAEIVMFMFAPRLLG 262 M ++Q+ +V++ + + GI A G + + M + Sbjct: 213 AALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAA 272 Query: 263 RYGVNTLLVVSIAMTAVRWLLVAFGVESMLLLGLSQVLHAFTFGLTHAASIQFVHRHFDA 322 R G L++ + ++L+AF + + +L + G+ A + R D Sbjct: 273 RLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGM--PALQAMLSRQVDE 330 Query: 323 SHRSQGQALYASLSFGVGGALGTWICGYIWGDGSGAVWSWVFAATCAFAAML 374 + Q Q A+L+ + +G + I+ W + A A + Sbjct: 331 ERQGQLQGSLAALT-SLTSIVGPLLFTAIYAASITTWNGWAWIAGAALYLLC 381
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 34.0 bits (78), Expect = 6e-04 Identities = 35/139 (25%), Positives = 53/139 (38%), Gaps = 19/139 (13%) Query: 28 LIALIANG--HLLVEGPPGLAKT---RAVKALCDGVEGDFHRIQ---FTPDLLPADLTG- 78 ++A + L++ G G K RA+ G F I DL+ ++L G Sbjct: 152 VLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGH 211 Query: 79 -----TDIYRSQTGTFEFEAGPIFHNLILADEINRAPAKVQSALLEAMAEGQVT-VGKNS 132 T TG FE G + DEI P Q+ LL + +G+ T VG + Sbjct: 212 EKGAFTGAQTRSTGRFEQAEG----GTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRT 267 Query: 133 YKLPPLFLVMATQNPLENE 151 + +V AT L+ Sbjct: 268 PIRSDVRIVAATNKDLKQS 286
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 24.9 bits (54), Expect = 0.044 Identities = 13/37 (35%), Positives = 20/37 (54%) Query: 1 MKKTSLALIAAMSMLGSVAANANTTGTTTGGAGAGGA 37 MKKT++A+ A++ +VA A T GA G + Sbjct: 1 MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWS 37
>PF06580#Sensor histidine kinase Length = 349 Score = 51.0 bits (122), Expect = 4e-09 Identities = 35/198 (17%), Positives = 74/198 (37%), Gaps = 38/198 (19%) Query: 266 NTMQDGLGLIERNLTRAAELV--------HNFKRTAADQSVLERERFNLKAYLFQIFSSL 317 N + + LI + T+A E++ ++ + + A Q L E + +YL + S Sbjct: 177 NALNNIRALILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQ-LAS-- 233 Query: 318 RPLMR-KKNIALTVELDEQIFIESYPGAIAQIFTNLVANSFRHGFPEHFTGDKKITIRVE 376 ++ + + +++ I P + Q LV N +HG KI ++ Sbjct: 234 ---IQFEDRLQFENQINPAIMDVQVPPMLVQT---LVENGIKHGI-AQLPQGGKILLKGT 286 Query: 377 KQGSNICMQYQDNGVGMTDEVKIKAFEPFFTTARKDGGTGLGMSIIYNLVTQKLHG---S 433 K + ++ ++ G K TG G+ + + Q L+G Sbjct: 287 KDNGTVTLEVENTGSLALKNTK--------------ESTGTGLQNVRERL-QMLYGTEAQ 331 Query: 434 ILLTSQPNQGVTIDIQLP 451 I L+ + + + + +P Sbjct: 332 IKLSEKQGKVNAM-VLIP 348
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 187 bits (477), Expect = 4e-59 Identities = 79/355 (22%), Positives = 137/355 (38%), Gaps = 51/355 (14%) Query: 1 MRILVTGGAGFIGSALVRMLIEQTESVVL--NFDKLTYASHPESLAGVADNERYHFVQAD 58 M+ LVTG AGFIG + + L+E VV N + S ++ + + F + D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 59 ICDRARLEQVLQQFQPDLMMHLAAESHVDRSIDGPAEFIQTNIVGTYTLLEACRSYYQTL 118 + DR + + + + V S++ P + +N+ G +LE CR Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ- 119 Query: 119 GQAQQRRFRLHHISTDEVFGSLTETGLFSETSAYD-PSSPYSASKASADHLVRAWHRTYA 177 L + S+ V+G L FS + D P S Y+A+K + + + + Y Sbjct: 120 --------HLLYASSSSVYG-LNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYG 170 Query: 178 LPIVITNCSNNYGPFQYPEKLIPLMVSNALQSKPLPIYGNGQQVRDWLYVDDHVKALYLV 237 LP YGP+ P+ + L+ K + +Y G+ RD+ Y+DD +A+ + Sbjct: 171 LPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRL 230 Query: 238 ------------------ATQGQLGQTYNIGGSCEQTNLTVVRHICSLLEELVPTHPQSL 279 A + YNIG S + + LE+ + Sbjct: 231 QDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYI----QALEDAL------- 279 Query: 280 AMGNAGFADLIQYVVDRPGHDVR--YAIDASKIQRELGWRPQESFESGLRKTVEW 332 G + +PG DV A D + +G+ P+ + + G++ V W Sbjct: 280 -----GIEAKKNMLPLQPG-DVLETSA-DTKALYEVIGFTPETTVKDGVKNFVNW 327
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 52.1 bits (125), Expect = 3e-09 Identities = 47/298 (15%), Positives = 101/298 (33%), Gaps = 44/298 (14%) Query: 283 VMVTGAGGSIGSELCRQILKQLPKQLVLFELSEFALYSIERELSATATELGIDVEIVPIM 342 +VTGA G IG + +++L+ + + + L+++ S+++ + G Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQF----HK 58 Query: 343 GSVQRENRVQAVMQAFKVQTVYHAAAYKHVPLVEHNVVEGVRNNVFGTLYTARAAIAAKV 402 + + + + + V+ + V N +N+ G L K+ Sbjct: 59 IDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKI 118 Query: 403 ETFVLVST---------------DKAVRPTNVMGTTKRMAELALQALAKENHHTRFCMVR 447 + + S+ D P ++ TK+ EL + + +R Sbjct: 119 QHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYS-HLYGLPATGLR 177 Query: 448 FGNVLGSSGS---VVPLFRKQIANGGPVTV-THPEITRFFMTIPEASQLVIQA------- 496 F V G G + F K + G + V + ++ R F I + ++ +I+ Sbjct: 178 FFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHA 237 Query: 497 -----------GAMGKGGDVFVLDMGKSVKIIDLAAKMIRLSGYDVKDEANP--NGDI 541 A V+ + V+++D + G + K P GD+ Sbjct: 238 DTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQPGDV 295
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 68.7 bits (168), Expect = 2e-15 Identities = 63/347 (18%), Positives = 116/347 (33%), Gaps = 65/347 (18%) Query: 5 SILLTGATGFVGQQILRQLPQDT-RVFG----------RTKPAR-------DCHFFAGEL 46 L+TGA GF+G + ++L + +V G K AR F +L Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 47 TANTDYRSAL---SGVDVVIHCAARAHVMNETANNAAQLYQEVNTLVTLALAEQAAAAGV 103 A+ + + L + V R V N A Y + N L + E + Sbjct: 62 -ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHA--YADSNLTGFLNILEGCRHNKI 118 Query: 104 KRFIFISTIKVNGEATIAGQLFRASD-ARQPLDHYGESKAKAEIGLFDIARKTEIEVVII 162 + ++ S+ V G F D P+ Y +K E+ + + + Sbjct: 119 QHLLYASSSSVYGLNRKMP--FSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGL 176 Query: 163 RPPLVYGPNVKANFATMLNLAKKNL----PLPFGAIHNKRSMVALDNLVDLIVTCIEHPN 218 R VYGP + + A + K L + KR +D++ + I+ + Sbjct: 177 RFFTVYGPWGRPDMA-LFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIP 235 Query: 219 AANQ-----------------IFLVSDDQDVSTTELLKLMTGAAGKKPRLLPVPMAWLIL 261 A+ ++ + + V + ++ + A G + + +P+ Sbjct: 236 HADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQ---- 291 Query: 262 AGKVTGNQAIIDRLCGNLQVDITHTKNTLSWQPPITVEEGVRRCFVK 308 G V A D + + P TV++GV+ FV Sbjct: 292 PGDVLETSA-----------DTKALYEVIGFTPETTVKDGVKN-FVN 326
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 38.4 bits (89), Expect = 3e-06 Identities = 18/59 (30%), Positives = 27/59 (45%) Query: 70 AYLSMLAVDPEYRGKGFAKKLILDMESTVRDNGFKTIRLEVYKTNEGALSMYLKLNYII 128 A + +AV +YR KG L+ ++N F + LE N A Y K ++II Sbjct: 90 ALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFII 148
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 175 bits (446), Expect = 4e-54 Identities = 82/376 (21%), Positives = 140/376 (37%), Gaps = 66/376 (17%) Query: 1 MKILVTGGAGFIGSAVVRHIIGNTQDCVVNVDKLT--YAGNLESLT-SVADSPRYTFEKV 57 MK LVTG AGFIG V + ++ VV +D L Y +L+ + P + F K+ Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQ-VVGIDNLNDYYDVSLKQARLELLAQPGFQFHKI 59 Query: 58 DICDRTELERVFSLHQPDAVMHLAAESHVDRSITGSADFIQTNIVGTYTLLEAARHYWMQ 117 D+ DR + +F+ + V V S+ + +N+ G +LE RH +Q Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ 119 Query: 118 LNTERKSAFRFHHISTDEVYGDLPHPDEINVECSMLNDECKDHSTLNIQHSTLPLFTETT 177 + S+ VYG +P T+ + Sbjct: 120 ---------HLLYASSSSVYGLNRK---------------------------MPFSTDDS 143 Query: 178 PYTPSSPYSASKASSDHLVRAWLRTYGFPTIVTNCSNNYGPYHFPEKLIPLVILNALEGK 237 P S Y+A+K +++ + + YG P YGP+ P+ + LEGK Sbjct: 144 VDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFFTVYGPWGRPDMALFKFTKAMLEGK 203 Query: 238 PLPIYGKGDQIRDWLYVEDHARALFKVV------------------TEGKVGETYNIGGH 279 + +Y G RD+ Y++D A A+ ++ YNIG Sbjct: 204 SIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNS 263 Query: 280 NEKRNLEVVQTICSILDSLVPKNTPYAEQIAYVADRPGHDRRYAIDATKMSAELDWQPQE 339 + ++ +Q + L KN + +PG + D + + + P+ Sbjct: 264 SPVELMDYIQALEDALGIEAKKN--------MLPLQPGDVLETSADTKALYEVIGFTPET 315 Query: 340 TFETGLRKTVEWYLAN 355 T + G++ V WY Sbjct: 316 TVKDGVKNFVNWYRDF 331
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 259 bits (663), Expect = 5e-87 Identities = 94/339 (27%), Positives = 160/339 (47%), Gaps = 30/339 (8%) Query: 19 LITGVAGFIGSNLLEQLLKLNQTVIGLDNFATGRQHNLDEVQSLVTSEQWMRFSFINGDI 78 L+TG AGFIG ++ ++LL+ V+G+DN +L + + + ++ F F D+ Sbjct: 4 LVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQP--GFQFHKIDL 61 Query: 79 RDYAICEAVV--NGVDYVLHQAALGSVPRSIADPITTNAANITGFLNMLQAAKEAEVKSF 136 D + + V +V S+ +P +N+TGFLN+L+ + +++ Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 137 TYAASSSTYGDHPALP-KVEQNIGNPLSPYAVTKYVNELYASVYARTYGFETIGLRYFNV 195 YA+SSS YG + +P + ++ +P+S YA TK NEL A Y+ YG GLR+F V Sbjct: 122 LYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFFTV 181 Query: 196 FGRRQDPNGAYAAVIPKWTSSMIKGEDVFINGDGETSRDFCYIDNVVQMNILAA------ 249 +G P+ A K+T +M++G+ + + G+ RDF YID++ + I Sbjct: 182 YGPWGRPDMAL----FKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHA 237 Query: 250 ----------TAASEAKNEVYNVAVGDRTTLNDLYFAIKDSLNANGINVNQNPNYRDFRA 299 AAS A VYN+ L D A++D+L + N + Sbjct: 238 DTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDAL-----GIEAKKNMLPLQP 292 Query: 300 GDVRHSQADVSKAVTRLGYQYTHKILEGISEAMPWYKEF 338 GDV + AD +G+ + +G+ + WY++F Sbjct: 293 GDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDF 331
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 93.7 bits (233), Expect = 4e-23 Identities = 36/154 (23%), Positives = 62/154 (40%), Gaps = 2/154 (1%) Query: 7 SILWVEDDPVFRQIVATFLSGRGAQVVQAGDGEQGLIHFKQQRFDIILADLSMPKLGGLD 66 +IL +DD R ++ LS G V + D+++ D+ MP D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 67 MLKEMSKLEPLVPSIVISGNNVMADVVEALRIGACDYLVKPVADLFIIEQAIQQGLQRHQ 126 +L + K P +P +V+S N ++A GA DYL KP DL + I + L + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPF-DLTELIGIIGRALAEPK 123 Query: 127 LDDISQTDLDVLSHQELSDNLTILEQSVEAAKQV 160 S+ + D L +++ ++ Sbjct: 124 R-RPSKLEDDSQDGMPLVGRSAAMQEIYRVLARL 156
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 229 bits (584), Expect = 2e-77 Identities = 88/224 (39%), Positives = 128/224 (57%), Gaps = 4/224 (1%) Query: 42 EDPRDPFEGFNRVMWDFNYLYLDRYLYRPVAHGYNDYIPLPAKMGVNNFLQNLEEPSSVV 101 + DP EGFNR M++FN+ LD Y+ RPVA + DY+P PA+ G++NF NLEEP+ +V Sbjct: 26 QGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWRDYVPQPARNGLSNFTGNLEEPAVMV 85 Query: 102 NNLLQGKWGWAANAGGRFTVNTTIGLLGVIDVADMMGMTRKQDE---FNEVLGYYGVPNG 158 N LQG RF +NT +G+ G IDVA M ++ E F LG+YGV G Sbjct: 86 NYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGMANPKLQRTEPHRFGSTLGHYGVGYG 145 Query: 159 PYFMAPFAGPYIVRELASDWVDGLYFPLSELTMWQSVLKWGLKSLHARASAIDQERLVDN 218 PY PF G + +R+ D D LY LS LT SV KW L+ + RA +D + L+ Sbjct: 146 PYVQLPFYGSFTLRDDGGDMADALYPVLSWLTWPMSVGKWTLEGIETRAQLLDSDGLLRQ 205 Query: 219 ALDPYAFVKDAYIQHMDYKVYDGNV-PQKQEDDELLDQYMQELE 261 + DPY V++AY Q D+ G + PQ+ + + + +++++ Sbjct: 206 SSDPYIMVREAYFQRHDFIANGGELKPQENPNAQAIQDDLKDID 249
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 55.5 bits (134), Expect = 1e-12 Identities = 18/87 (20%), Positives = 32/87 (36%), Gaps = 3/87 (3%) Query: 7 TQQAVALSYD-GKH-APKVVASGEGLVADEIIALAKASGVYIHQDPHLSNFL-RLLELGE 63 T A+ + Y G+ P V + +A+ GV I Q L+ L + Sbjct: 265 THIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIAEEEGVPILQRIPLARALYWDALVDH 324 Query: 64 EIPRELYLLIAELIAFVYMLDGKFPEQ 90 IP E AE++ ++ + + Sbjct: 325 YIPAEQIEATAEVLRWLERQNIEKQHS 351
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 29.2 bits (65), Expect = 0.018 Identities = 16/88 (18%), Positives = 28/88 (31%) Query: 79 KSIVTVSTKENAEPLVNKQALERLLAPVLKTQAPDIPKPTELNEQPLPLPKPVEAIAVTN 138 S+ V+ + P + E ++ P + + P P PKP Sbjct: 50 ISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVK 109 Query: 139 VVKPADVESQQVEIISTAPETQVGFAPP 166 V+ + + VE +P A P Sbjct: 110 KVEQPKRDVKPVESRPASPFENTAPARP 137
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 44.6 bits (105), Expect = 2e-07 Identities = 19/119 (15%), Positives = 41/119 (34%), Gaps = 4/119 (3%) Query: 145 EDATSITVSAEGEVSVKTPGAAENQVVGQLSMTDFINPSGLDPMGQNLYTETG---ASGT 201 D I +++E + + + Q + + +L ++ G A+ Sbjct: 427 TDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGNKTATLK 486 Query: 202 PIQGTASLDGMGAIRQGALETSNVNVTEELVNLIESQRIYEMNSKVISAVDQMLAYVNQ 260 T + + S VN+ EE NL Q+ Y N++V+ + + + Sbjct: 487 TSSATQGNV-VTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALIN 544 Score = 36.5 bits (84), Expect = 9e-05 Identities = 9/36 (25%), Positives = 21/36 (58%) Query: 5 LWISKTGLDAQQTDISVISNNVANASTVGYKKSRAV 40 + + +GL+A Q ++ SNN+++ + GY + + Sbjct: 4 INNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTI 39
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 40.3 bits (94), Expect = 1e-05 Identities = 15/35 (42%), Positives = 22/35 (62%) Query: 2 SFNIALSGISAAQKDLNTTANNIANANTIGFKESR 36 N A+SG++AAQ LNT +NNI++ N G+ Sbjct: 3 LINNAMSGLNAAQAALNTASNNISSYNVAGYTRQT 37 Score = 37.2 bits (86), Expect = 1e-04 Identities = 13/49 (26%), Positives = 25/49 (51%) Query: 405 SLSSSALEQSNIDLTTELVDLISAQRNFQANSRTLEVNNTLQQTVLQIR 453 LS+ S ++L E +L Q+ + AN++ L+ N + ++ IR Sbjct: 498 QLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR 546
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 33.0 bits (75), Expect = 3e-04 Identities = 9/38 (23%), Positives = 18/38 (47%) Query: 99 NVNVMEEMADMISASRSYQMNVQVAEAAKSMLQQTLGM 136 VN+ EE ++ + Y N QV + A ++ + + Sbjct: 508 GVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545 Score = 28.4 bits (63), Expect = 0.010 Identities = 15/64 (23%), Positives = 27/64 (42%), Gaps = 6/64 (9%) Query: 8 DVAGSGMSAQSLRLNTTASNIANADSVSSSIDKTYRSRHPIFEAEMAKAQSQQQASQGVA 67 + A SG++A LNT ++NI++ + Y + I + + GV Sbjct: 5 NNAMSGLNAAQAALNTASNNISSYN------VAGYTRQTTIMAQANSTLGAGGWVGNGVY 58 Query: 68 VKGI 71 V G+ Sbjct: 59 VSGV 62
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 60.6 bits (147), Expect = 2e-12 Identities = 23/128 (17%), Positives = 53/128 (41%), Gaps = 12/128 (9%) Query: 180 HIMVIDDSAVARKQIIRSLESLNLQIDTAKDGREALDKLKAIASEMNNVADEIPLIISDI 239 I+V DD A R + ++L + + + A + L+++D+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAA---------GDGDLVVTDV 55 Query: 240 EMPEMDGYTLTAEIRDDPKLKNIKVVLHTSLSGVFNQAMVQKVGANDFIAK-FNPDELAA 298 MP+ + + L I+ ++ V++ ++ + + GA D++ K F+ EL Sbjct: 56 VMPDENAFDLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIG 113 Query: 299 AVNKHLSL 306 + + L+ Sbjct: 114 IIGRALAE 121
>FRAGILYSIN#Fragilysin metallopeptidase (M10C) enterotoxin signature. Length = 405 Score = 27.0 bits (59), Expect = 0.029 Identities = 16/48 (33%), Positives = 24/48 (50%), Gaps = 1/48 (2%) Query: 1 MKRYLLVIAALLLTGCAAK-DKYVEWEDVPPTSFPKLTAIGYAPLATQ 47 +K L++ A LL C+ + D D P T+ L ++ Y LATQ Sbjct: 12 VKLLLMLGTAALLAACSNEADSLTTSIDAPVTASIDLQSVSYTDLATQ 59
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 91.3 bits (226), Expect = 3e-24 Identities = 59/253 (23%), Positives = 105/253 (41%), Gaps = 12/253 (4%) Query: 3 KLVLITGGSRGIGAGIAKAFAEAGYWVAITYLNH--QDKAVSLANILGDKVAAFALDQSK 60 K+ ITG ++GIG +A+ A G +A N +K VS AF D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 61 PESIKQCITEVEKYFNRSIDVLINNGAIAQEKPFSDITADDFTTMLNTNLRGPFLLAQAC 120 +I + +E+ ID+L+N + + ++ +++ + N G F +++ Sbjct: 69 SAAIDEITARIEREMGP-IDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 121 IPAMQQHGFGRIINIGSIGGQWGGYNQVHYAAAKAGLINLSQSIAKIYSRDGIRTNTIAI 180 M G I+ +GS + YA++KA + ++ + + IR N ++ Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 181 GLVATEMTEHELTTEAGKQKAAA---------IPVGRLGKVEDIASIALFLASQDSDYLS 231 G T+M E G ++ IP+ +L K DIA LFL S + +++ Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHIT 247 Query: 232 GQTLNANGGMYFG 244 L +GG G Sbjct: 248 MHNLCVDGGATLG 260
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 30.2 bits (68), Expect = 0.008 Identities = 19/68 (27%), Positives = 33/68 (48%), Gaps = 7/68 (10%) Query: 59 IAVYTNPGRQGLPSSAKIRDLDEQIQFIKRGIGHLPKSAMQIGSSDGYTLSRFRQAGVEL 118 +AV NP +Q + S + E+++ I + I HLP + + +R RQAG + Sbjct: 32 VAVLRNPNKQPMFS------VQERLEQIAKAIAHLPNAQVDSFEGLTVNYARQRQAGA-I 84 Query: 119 VMGVEPGS 126 + G+ S Sbjct: 85 LRGLRVLS 92
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 80.2 bits (198), Expect = 3e-19 Identities = 43/245 (17%), Positives = 86/245 (35%), Gaps = 54/245 (22%) Query: 6 TILITGGTGSFGQKYTKTILERY-----------------KPKRLIIFSRDELKQYEMQQ 48 L+TG G G +K +LE K RL + ++ + ++ Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHK--- 58 Query: 49 VFNAPCMRYFIGDVRDGERLKQAFKDVDF--VIHAAALKQVPAAEYNPMECIKTNIHGAE 106 D+ D E + F F V + V + NP +N+ G Sbjct: 59 -----------IDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFL 107 Query: 107 NVIRAAISNNVKKVIALST---------------DKAASPINLYGATKLASDKLFVAANN 151 N++ N ++ ++ S+ D P++LY ATK A++ + ++ Sbjct: 108 NILEGCRHNKIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSH 167 Query: 152 VVGDGKTRFAAVRYGNVVGSRGS---VVPFFKQLIANGATSLPITHPDMTRFWITLQDGV 208 + G +R+ V G G + F + + G + + M R + + D Sbjct: 168 LYG---LPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIA 224 Query: 209 DFVLK 213 + +++ Sbjct: 225 EAIIR 229
>PF07520#Virulence protein SrfB Length = 1041 Score = 31.1 bits (70), Expect = 0.013 Identities = 14/68 (20%), Positives = 29/68 (42%), Gaps = 2/68 (2%) Query: 330 AQLAVLASGTKEKPNMPFVFCGEATANHAEGFKAAYRDGAIKKSETLEELAKRYDVDINA 389 Q+A+ + + + + +V A + F+ GA+ S L+ L D + Sbjct: 148 VQIALDTALSDQDQSAHYVAPERADSEKPREFRLVSDPGAM--SWFLQRLEADEDGNAVD 205 Query: 390 LQNSINEW 397 LQ +++W Sbjct: 206 LQLWVSDW 213
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 107 bits (269), Expect = 3e-27 Identities = 60/278 (21%), Positives = 99/278 (35%), Gaps = 76/278 (27%) Query: 161 KVIKETPTELQTDNGPQLIGASNLWDGNATGLAAKGDGIIIGILDTGINTDNRAFSAVGD 220 +VIK+ + G ++I A +W+ +G G+ + +LDTG + D+ Sbjct: 11 QVIKQEQQVNEIPRGVEMIQAPAVWNQT------RGRGVKVAVLDTGCDADHPDLK---- 60 Query: 221 DGHNIINPLGSGNYLGDCVKDATLCNDKLIGVYSFPLVTDEYNGLRPANGEDYNGHGSHT 280 ++IG +F + + P +DYNGHG+H Sbjct: 61 --------------------------ARIIGGRNF----TDDDEGDPEIFKDYNGHGTHV 90 Query: 281 ASTAAGNALVNVPVLMPNIGEEVGDGIETGTVLSNISGVAPHANIISYQVCDQSGCYP-S 339 A T A G + GVAP A+++ +V ++ G Sbjct: 91 AGTIAATE--------NENG---------------VVGVAPEADLLIIKVLNKQGSGQYD 127 Query: 340 LTIASVELAIKAGVDVLNYSIGPRGGVQNDPWNTASDIAFLSAREAGIFVAMAAGNAGPD 399 I + AI+ VD+++ S+G V A A + I V AAGN G Sbjct: 128 WIIQGIYYAIEQKVDIISMSLGGPEDV------PELHEAVKKAVASQILVMCAAGNEGDG 181 Query: 400 AETVGNV-----APWAISVAASSHQRVWSHVLS-GSGV 431 + + ISV A + R S + + V Sbjct: 182 DDRTDELGYPGCYNEVISVGAINFDRHASEFSNSNNEV 219 Score = 71.0 bits (174), Expect = 5e-15 Identities = 32/132 (24%), Positives = 51/132 (38%), Gaps = 33/132 (25%) Query: 578 DILADFSSRGPYKWQTELMVPHIAAPGVDIYAAYADEMPFTSVNDAAPSDFAFLSGTSMA 637 ++FS+ + APG DI + +A SGTSMA Sbjct: 207 RHASEFSNSNNE--------VDLVAPGEDILSTVPG------------GKYATFSGTSMA 246 Query: 638 SPHVAGSAALLRQL-----HPDWTPAEIQSAMMLTATTNVLKEDGKTPAGIFDIGSGRLQ 692 +PHVAG+ AL++QL D T E+ + ++ G +P G+G L Sbjct: 247 TPHVAGALALIKQLANASFERDLTEPELYAQLIKRTIP-----LGNSP---KMEGNGLLY 298 Query: 693 IDKAAQAGLVMD 704 + + + D Sbjct: 299 LTAVEELSRIFD 310
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 49.4 bits (118), Expect = 3e-09 Identities = 26/120 (21%), Positives = 53/120 (44%), Gaps = 5/120 (4%) Query: 6 HVMIADDHPLYLDALVNGLVSHLPGTQVSQANNYIELFDSLYLQVEEIDLLIMDLFMPGS 65 +++ADD L L G V +N L+ ++ + DL++ D+ MP Sbjct: 5 TILVADDDAAIRTVLNQALSRA--GYDVRITSNAATLWR--WIAAGDGDLVVTDVVMPDE 60 Query: 66 SGYAGLSFLRTQFPTLPIVVISALDDLIARSQCIQHGA-AFISKSTAPTNIFKQVEQILD 124 + + L ++ P LP++V+SA + + + + GA ++ K T + + + L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120
>PF06580#Sensor histidine kinase Length = 349 Score = 30.6 bits (69), Expect = 0.035 Identities = 15/107 (14%), Positives = 38/107 (35%), Gaps = 18/107 (16%) Query: 935 SLLLRRVIDNILSNAIKISDPDTSVSLSVCQERQHAVIEVIDQGPGMTQQMQAELFTPFK 994 +L++ +++N + + I + L ++ +EV + G + + Sbjct: 257 PMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTK-------- 308 Query: 995 RWTSRYQGSGLGLS-VVKGIADLLG--ISLSIRSTLGEGTQFTLKLP 1038 + +G GL V + + L G + + G + +P Sbjct: 309 ------ESTGTGLQNVRERLQMLYGTEAQIKLSEKQG-KVNAMVLIP 348
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 32.9 bits (75), Expect = 0.003 Identities = 38/159 (23%), Positives = 67/159 (42%), Gaps = 35/159 (22%) Query: 199 IKLAIIGKPNVGKSTLTNRIL----GEERVVVYDEPGTTRDSIYIPMER----------- 243 I + ++ + GK+TLT +L + D+ T D+ + +R Sbjct: 4 INIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSF 63 Query: 244 --DGREYVIIDTAGVRRRSKVHEVIEKFSVIKTLKAVEDANVVLLIIDAREGVAEQDLGL 301 + + IIDT G + + E V ++L ++ A +L+I A++GV Q L Sbjct: 64 QWENTKVNIIDTPG-----HMDFLAE---VYRSLSVLDGA---ILLISAKDGVQAQTRIL 112 Query: 302 LGFALNAGRALVIAVNKWD--GID-----QGIKDRVKSE 333 G + +NK D GID Q IK+++ +E Sbjct: 113 FHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAE 151
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 29.9 bits (67), Expect = 0.018 Identities = 23/102 (22%), Positives = 46/102 (45%), Gaps = 19/102 (18%) Query: 23 AVLLSVTP-SYIATLDQTDSAA-----AARLRKLKENIEAPLV-----------SILTLN 65 AV L+++P S+++ D+ A + R +KL + ++ L S+ T++ Sbjct: 313 AVTLAISPLSFLSIADKFKRANKIEEYSQRFKKLGYDGDSLLAAFHKETGAIDASLTTIS 372 Query: 66 TVAHTVGAAVAGAQAAKVFGDDMLGVFSGVLTFI--ILFFSE 105 TV +V + ++ A + G + + V I IL S+ Sbjct: 373 TVLASVSSGISAAATTSLVGAPVSALVGAVTGIISGILEASK 414
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 28.4 bits (63), Expect = 0.012 Identities = 15/79 (18%), Positives = 35/79 (44%), Gaps = 3/79 (3%) Query: 75 GASLTKICAGFINVETDFRHRGYIDSLYIHPDWQRQGLGELAYRQLEQWARAQGYSQL-- 132 L C G I + +++ I+ + + D++++G+G + +WA+ + L Sbjct: 69 LYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLML 128 Query: 133 -STDASYLSRGLFIKLGFI 150 + D + + + K FI Sbjct: 129 ETQDINISACHFYAKHHFI 147
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 73.0 bits (179), Expect = 1e-17 Identities = 32/118 (27%), Positives = 51/118 (43%), Gaps = 12/118 (10%) Query: 90 VYFEFAIAEVDLSQWKALALVKSFLEAN--TETKLTLVGHTDIVGTPEFNYQLSLQRAQN 147 V F F A + AL + S L + + ++G+TD +G+ +N LS +RAQ+ Sbjct: 221 VLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQS 280 Query: 148 VKRILVEDYGFNPNRFTVVGKGISEPVADNRSSEGRGL---------NRRVQFIVNNI 196 V L+ G ++ + G G S PV N + +RRV+ V I Sbjct: 281 VVDYLISK-GIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKGI 337
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 26.6 bits (58), Expect = 0.016 Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 12/80 (15%) Query: 12 KEADGLDFQLYPGDLGKRIFDNISKEAWG----------LWQKKQTMLINEKKLNMMNVD 61 K + LD DL +R D SK G L Q K+T+ +K N +N Sbjct: 362 KYREALDIHY--EDLIRRKTDGSSKFINGREIDAVTNDALIQAKRTISAIDKPKNFLNQK 419 Query: 62 DRKFLEAQMTSFLFEGKDVE 81 +RK ++A + + +GK E Sbjct: 420 NRKQIKATIEAANQQGKRAE 439
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 30.6 bits (69), Expect = 0.034 Identities = 33/168 (19%), Positives = 65/168 (38%), Gaps = 31/168 (18%) Query: 32 AEATAAAPENIEKIEVRGMRASMKASVNDKRFSDSVVDAVTAEDIGKFPDGDVGESLARI 91 AT P+ +++ + ++S + SD+ T +DI + +V ++L+R+ Sbjct: 112 QLATPLLPQEVQQQGISVEKSSSSYLMVAGFVSDN--PGTTQDDISDYVASNVKDTLSRL 169 Query: 92 PGVAVNRQFGQGQQVSIRGASNQLTRTLLNGHTVASTGWFDQQAIDRSFNYSLLPPELVG 151 GV + FG + I W D + Y L P +++ Sbjct: 170 NGVGDVQLFGAQYAMRI---------------------WLDADLL---NKYKLTPVDVIN 205 Query: 152 GILVNKSSQADIAEGGVGGTITVK-TRKPLDLEANSLFLSAKGDYGTV 198 + K IA G +GGT + + + A + F + + ++G V Sbjct: 206 QL---KVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKNPE-EFGKV 249
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 28.7 bits (64), Expect = 0.006 Identities = 13/49 (26%), Positives = 25/49 (51%), Gaps = 3/49 (6%) Query: 5 QYGFSLIELITTLSISTLLISIGAPTYT---DITDHIRADSNIKTIQQT 50 Q GF+L+E++ + I +L S+ P + D +A S+I ++ Sbjct: 7 QRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENA 55
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 34.5 bits (79), Expect = 7e-05 Identities = 13/27 (48%), Positives = 19/27 (70%) Query: 6 KGFTLVELMVTIAIAALLLSVGVPSFT 32 +GFTL+E+MV I I +L S+ VP+ Sbjct: 8 RGFTLLEIMVVIVIIGVLASLVVPNLM 34
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 57.6 bits (139), Expect = 9e-14 Identities = 23/63 (36%), Positives = 41/63 (65%) Query: 4 KDKGFTLIEVMIVVVIIGILSAIAYPSYTRYVAQSTRAEGLSALMKLANLQEQYYLDNRK 63 K +GFTL+E+M+V+VIIG+L+++ P+ ++ + + +S ++ L N + Y LDN Sbjct: 6 KQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDNHH 65 Query: 64 YAT 66 Y T Sbjct: 66 YPT 68
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 157 bits (397), Expect = 6e-47 Identities = 86/376 (22%), Positives = 142/376 (37%), Gaps = 56/376 (14%) Query: 2 MKNTLK--VVLLTSMLPLAASASQELTPWYVGAGLGVNNYEHIATDNGD----DNPYAWD 55 MK T V L +A +A ++ T WY GA LG + Y N + +N Sbjct: 1 MKKTAIAIAVALAGFATVAQAAPKDNT-WYTGAKLGWSQYHDTGFINNNGPTHENQLGAG 59 Query: 56 IFAGYMFNDYFGAEIGYRDLGSADWTTGGISNDAGVKGATLGLVGVWPLGNRWSLSAEAG 115 F GY N Y G E+GY LG + + +G L +P+ + + G Sbjct: 60 AFGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPITDDLDIYTRLG 119 Query: 116 AMYYTLENSQHTGTTSSSYSSNDFAPYVGAGVGYNFTDNLKLQAKYRRYENLDDTDFNTI 175 M + + + +P GV Y T + + +Y+ N+ D Sbjct: 120 GMVWRADTKSNV---YGKNHDTGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDAHTIGT 176 Query: 176 EADSNYWGLELSYRFGTPAAAAPVAAAVVAAAPVDSDNDGVYDDKDECPATPATHKVDSV 235 D+ L +SYRFG AA VA A A V + + + D Sbjct: 177 RPDNGMLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKHFTLKSD---------------- 220 Query: 236 GCTLYENVKKQEDVGSIQFANDSAVVKKEYYKDIERLANYM--NKNPEFTVEIAGHASNV 293 + F + A +K E +++L + + + +V + G+ + Sbjct: 221 ----------------VLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRI 264 Query: 294 GKPEYNMVLSDKRADAVAKILVEKYGISQSRVTSNGYGITKPLVAGNS----------KE 343 G YN LS++RA +V L+ K GI ++++ G G + P V GN+ + Sbjct: 265 GSDAYNQGLSERRAQSVVDYLISK-GIPADKISARGMGESNP-VTGNTCDNVKQRAALID 322 Query: 344 AHAANRRIEAIVTTTE 359 A +RR+E V + Sbjct: 323 CLAPDRRVEIEVKGIK 338
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 43.7 bits (103), Expect = 3e-06 Identities = 35/180 (19%), Positives = 66/180 (36%), Gaps = 30/180 (16%) Query: 552 LEGEREKLLQMEVALHER--VIGQNEAVDAVANAIRRSRAGLADPNRPIGSFLFLGPTGV 609 L + + ++E + ++G++ A+ + + R L + + + G +G Sbjct: 119 LAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLAR----LMQTDLTL---MITGESGT 171 Query: 610 GKTELCKSLARFLFDSESALVRIDMSEFMEKHAVSRLVGAPPGYVGYEEGGYLTEAVRRK 669 GK + ++L + V I+M+ S L G +E+G + T A R Sbjct: 172 GKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFG-------HEKGAF-TGAQTRS 223 Query: 670 PYSV-------ILLDEVEKAHPDVFNILLQVLDDG---RLTDGQGRTVDFRNTVIIMTSN 719 + LDE+ D LL+VL G + D R I+ +N Sbjct: 224 TGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVR---IVAATN 280 Score = 30.2 bits (68), Expect = 0.040 Identities = 14/68 (20%), Positives = 29/68 (42%), Gaps = 3/68 (4%) Query: 151 DPNAEDQRQALKKFTVDLTERAEQG-KLDPVIGRDDEIRRTIQVLQRRTKNN-PVLI-GE 207 +AL + ++ + P++GR ++ +VL R + + ++I GE Sbjct: 109 TELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGE 168 Query: 208 PGVGKTAI 215 G GK + Sbjct: 169 SGTGKELV 176
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 30.8 bits (69), Expect = 0.016 Identities = 29/241 (12%), Positives = 81/241 (33%), Gaps = 8/241 (3%) Query: 266 IAEAANTVTSSATELSSFTQETNKRMQQQQAETEQTATAMNEMTATVAEVAQSTSAAANS 325 ++ A + V E+ + + + + AE + A NE+ A+ + Sbjct: 198 LSAAQSEVVKMDGEIKTLNSRLSSSIHARDAEMKTLAGKRNELAQASAKYKELDELVKKL 257 Query: 326 AKDADTYAA-----NGNRIVIDSISSMSQLSEQIQKTAQVIGFLSNESQNIGRVLDVIKS 380 + A+ R + + + +Q+ + I ++ + I + + + + Sbjct: 258 SPRANDPLQNRPFFEATRRRVGAGKIREEKQKQVTASETRINRINADITQIQKAISQVSN 317 Query: 381 IAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLAQRTQKSTQEIEAMIATLQQGVKQ 440 + ++ A E + + + + D V Q T++ + + Q + Sbjct: 318 NRNAG-IARVHEAEENLKKAQNNLLNSQIKDAVDATVSFYQTLTEKYGEKYSKMAQEL-- 374 Query: 441 AVSAMEVGIKQVDDANNKANQAGQALKEIVASVDNIAELNTHIATAAEEQSSVAENINRS 500 A + I V++A + L + + D A N + ++ + + + Sbjct: 375 ADKSKGKKIGNVNEALAAFEKYKDVLNKKFSKADRDAIFNALASVKYDDWAKHLDQFAKY 434 Query: 501 I 501 + Sbjct: 435 L 435
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 55.8 bits (134), Expect = 2e-11 Identities = 24/143 (16%), Positives = 53/143 (37%), Gaps = 3/143 (2%) Query: 15 QLLDTAEQLIDEQGVVSFRFAQIAKKSECSTNTLYKYFESKEDVL-ACLFLRNTTSIQIP 73 +LD A +L +QGV S +IAK + + +Y +F+ K D+ L + ++ Sbjct: 15 HILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELE 74 Query: 74 IFINENPNLTIHEHTLLPILFTFEAIKRSPIFNVLRVVSINSMFWQLASTQKIDVLKNRV 133 + ++ E+ +L + + + + + + Sbjct: 75 LEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCE-FVGEMAVVQQAQRNL 133 Query: 134 NL-FWSRIKTPLEDAVKEGELKA 155 L + RI+ L+ ++ L A Sbjct: 134 CLESYDRIEQTLKHCIEAKMLPA 156
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 57.7 bits (139), Expect = 5e-12 Identities = 16/79 (20%), Positives = 34/79 (43%), Gaps = 4/79 (5%) Query: 196 PQPTYPRMARKKGLEGTATIEVMFNEFGQQLALTLVKSSGVSLLDQAALEAVETWQFEAP 255 QP YP A+ +EG ++ G+ + ++ + ++ ++ A+ W++E Sbjct: 163 NQPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPG 222 Query: 256 SPKLASHYKVRVPIRFALN 274 P + V I F +N Sbjct: 223 KP----GSGIVVNILFKIN 237
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 46.4 bits (110), Expect = 2e-07 Identities = 30/162 (18%), Positives = 56/162 (34%), Gaps = 1/162 (0%) Query: 221 APAYASNLGLPPEKVATYMTATILAGLLAQWPMGKLSDIMSRSRLIRINCVLLGILALGI 280 P A++ PP TA +L + GKLSD + RL+ ++ ++ Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 281 ALTPYHPTVSLVMTFLFGILGFTFYPLATALANSRVEQSERVGLSATILLTFGMGASIGP 340 + ++ ++ F+ G F L + + + R I MG +GP Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 341 LIASTLMQWFGNSMLYGFMSACTVILFLRLRYVHSQQKAETN 382 I + + S L T+I L + ++ Sbjct: 157 AIGGMIAHYIHWSYLLLIPMI-TIITVPFLMKLLKKEVRIKG 197 Score = 31.0 bits (70), Expect = 0.010 Identities = 25/137 (18%), Positives = 55/137 (40%), Gaps = 12/137 (8%) Query: 213 IVGSFYGLAPAYASNLGLPPEKVATYMTATILAGLLAQWPMGKLSDIMSRSRLIRINCVL 272 ++ + L+ A ++ + P + I+ G + G L D ++ I Sbjct: 282 MMKDVHQLSTAEIGSVIIFPG-----TMSVIIFGYIG----GILVDRRGPLYVLNIGVTF 332 Query: 273 LGILALGIALTPYHPTV--SLVMTFLFGILGFTFYPLATALANSRVEQSERVGLSATILL 330 L + L + + ++++ F+ G L FT ++T +++S +Q G+S Sbjct: 333 LSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFT 392 Query: 331 TFGMGASIGPLIASTLM 347 +F + G I L+ Sbjct: 393 SF-LSEGTGIAIVGGLL 408
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 82.6 bits (204), Expect = 2e-20 Identities = 31/131 (23%), Positives = 61/131 (46%), Gaps = 1/131 (0%) Query: 1 MQNPHILIVEDEAVTRNTLRSIFEAEGYVVTEANDGAEMHKAMQENKINLVVMDINLPGK 60 M IL+ +D+A R L GY V ++ A + + + +LVV D+ +P + Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 NGLLLARELREIN-NIGLIFLTGRDNEVDKILGLEIGADDYITKPFNPRELTIRARNLLT 119 N L +++ ++ ++ ++ ++ + I E GA DY+ KPF+ EL L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 120 RVNSAGNEVEE 130 +++E+ Sbjct: 121 EPKRRPSKLED 131
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 69.5 bits (170), Expect = 6e-14 Identities = 26/132 (19%), Positives = 55/132 (41%), Gaps = 2/132 (1%) Query: 1352 LLLVEDNYLNQELAVELLRQAGARVTVAQHGQEALTLLAQQSFDCVLMDGQMPVMDGYEA 1411 +L+ +D+ + + + L +AG V + + +A D V+ D MP + ++ Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 1412 TRLIRAQPQFADLPIIAMTANAMDSDRERALAAGMNAQINKPFQVQQLYSTIAQHVSVHS 1471 I+ DLP++ M+A +A G + KPF + +L I + ++ Sbjct: 66 LPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 1472 VQSLPESPEAHD 1483 + ++ D Sbjct: 124 RRPSKLEDDSQD 135
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 75.6 bits (186), Expect = 3e-17 Identities = 40/161 (24%), Positives = 69/161 (42%), Gaps = 16/161 (9%) Query: 6 TKPIVLVVDDSADNIQILHGLLSD-KYSIRAATSGAKALALAAIEPMPDLILLDVMMPEM 64 T +LV DD A +L+ LS Y +R ++ A A DL++ DV+MP+ Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGD-GDLVVTDVVMPDE 60 Query: 65 DGFQTCIRLK-HNPLTRHIPIIFVTAKTDIVDERTGFELGAVDYISKPVKPAILEARVKT 123 + F R+K P +P++ ++A+ + E GA DY+ KP Sbjct: 61 NAFDLLPRIKKARP---DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDL-------TE 110 Query: 124 HLTLASRANQLESLVQLRTQELESARYKIIHKLGRAAEFRD 164 + + RA + R +LE + +GR+A ++ Sbjct: 111 LIGIIGRALAEP---KRRPSKLEDDSQDGMPLVGRSAAMQE 148
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 52.4 bits (125), Expect = 8e-09 Identities = 53/316 (16%), Positives = 102/316 (32%), Gaps = 10/316 (3%) Query: 598 EYAASEQELRIRLSKAEEALQSAQELQAEAESQLVAINGELDKLSRELTFARTAYKNSRD 657 EL LS A+E L+ + +E S++ + L + L A Sbjct: 82 ALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSA 141 Query: 658 DLRRLFDEKRSEQDKINKALAERKAFAQQRLTQLDGELKQLKHQHQLWLEEQKEQALEAR 717 ++ L EK + KA K + + E ++ LE Sbjct: 142 KIKTLEAEK---AALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKA 198 Query: 718 MEKQAYWQEVIGALDNQLGQIKATIDARRESAKAEQKACETWYKNELKSRGVDEDNILKL 777 +E + A L KA + AR+ + + + + E L Sbjct: 199 LEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAAL 258 Query: 778 KQQIRELETKISRAEQRRSEVLRFDDWY-----QHTWLIRKPKLQTQLSDVKR-AASEID 831 + + ELE + A + + Q+Q+ + R + Sbjct: 259 EARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDL 318 Query: 832 QQLKAKTQEVKTRRQQLETERKASDAAQIEASENLTKLRAVMRKLAELKLPANNEEAQGS 891 + ++++ Q+LE + K S+A++ +L R ++L E + E+ + S Sbjct: 319 DASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQL-EAEHQKLEEQNKIS 377 Query: 892 LGERLRQGEDLLLKRD 907 R DL R+ Sbjct: 378 EASRQSLRRDLDASRE 393 Score = 34.7 bits (79), Expect = 0.002 Identities = 38/348 (10%), Positives = 104/348 (29%), Gaps = 27/348 (7%) Query: 374 QTEKHQDIEAAYNARRSKIGEQLNRELEGLHSEQDKQREARDKQREVARGDLDALEAQWR 433 E + K+ E+ ++ ++ + K + + L+ Sbjct: 37 TNEVSAVATRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKA--------LKDHND 88 Query: 434 SQMDAGKASFSEQEYQFKLNAAELKLRVDGVTYTEEEKLNLAIFDERIHRADEEQESCNA 493 + + + K + + + + + L + ++ A Sbjct: 89 ELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEA 148 Query: 494 KVERLTSDERKLRAKRDQANEALRIASLRVNERQTALDEL---------HHMLFPQSHTL 544 + L + + L + A S ++ + L T Sbjct: 149 EKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTA 208 Query: 545 LEFLRKEAQGWEQSLGKVIAPELLHRTDLHPSVTGESDTVFGVNLDLKAID--------- 595 K + + +L A T +S + + + A++ Sbjct: 209 DSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKA 268 Query: 596 VPEYAASEQELRIRLSKAEEALQSAQELQAEAESQLVAINGELDKLSRELTFARTAYKNS 655 + ++ E + + +A+ E Q +N L R+L +R A K Sbjct: 269 LEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQL 328 Query: 656 RDDLRRLFDEKRSEQDKINKALAERKAFAQQRLTQLDGELKQLKHQHQ 703 + ++L ++ + + ++L +++ QL+ E ++L+ Q++ Sbjct: 329 EAEHQKLEEQNKI-SEASRQSLRRDLDASREAKKQLEAEHQKLEEQNK 375
>PERTACTIN#Pertactin signature. Length = 922 Score = 34.3 bits (78), Expect = 3e-04 Identities = 25/74 (33%), Positives = 30/74 (40%), Gaps = 4/74 (5%) Query: 140 AAPAQNQYAPAPQAAPAYQAPAPQPQSGYNQPPAQQSYGQQQAQPHVQPHAQPQQGGYAP 199 AA Q++ AP PAPQP P Q Q QP P QP+ AP Sbjct: 553 AANGNGQWSLVGAKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPE----AP 608 Query: 200 KPAAPAYQAPAAPA 213 P PA + +A A Sbjct: 609 APQPPAGRELSAAA 622
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 78.7 bits (194), Expect = 5e-18 Identities = 75/368 (20%), Positives = 135/368 (36%), Gaps = 29/368 (7%) Query: 11 KKVAFSLASVFGLRMMGLFMIMPV--FALYGQHLEGFSPLWVGIAIGAYGLTQAVLQIPM 68 + + L++V L +G+ +IMPV L GI + Y L Q + Sbjct: 5 RPLIVILSTVA-LDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVL 63 Query: 69 GILSDKYGRKPVILAGLVVFAIGSVIAANAETIYGVVFGRAVQGM-GAIAAAVLALAADL 127 G LSD++GR+PV+L L A+ I A A ++ + GR V G+ GA A A AD+ Sbjct: 64 GALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADI 123 Query: 128 TRDEQRTKVMAIIGMCIGLSFALSLLMGPIVAQHLGLTGLFWLTALLAILGMLLIQFLVP 187 T ++R + + C G ++G ++ F+ A L L L FL+P Sbjct: 124 TDGDERARHFGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFAAAALNGLNFLTGCFLLP 182 Query: 188 NPITQAPKGDTLATPAKLKRMFFEPQLFRLNAGIFILHLVLTAVFVALPLDLVDAGL--- 244 + L FR G+ ++ ++ F+ + V A L Sbjct: 183 ESHKGERRPLRREALNPLAS-------FRWARGMTVVAALMAVFFIMQLVGQVPAALWVI 235 Query: 245 --VKEKHW-------MLYFPAFVGAFF-LMVPLIIIGVKRKNTKAMFQIALVIMMFALAA 294 HW L + + M+ + + M + + L A Sbjct: 236 FGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLA 295 Query: 295 MAIFASNLWVLSVAVLLFFTGFNYLEASLPSLIAKFCPVGEKGSAMGVYSTSQFLGAFCG 354 FA+ W+ +++ +L +++++ +G G + L + G Sbjct: 296 ---FATRGWMA-FPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVG 351 Query: 355 GMLGGGAF 362 +L + Sbjct: 352 PLLFTAIY 359
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 67.7 bits (165), Expect = 4e-15 Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 5/85 (5%) Query: 285 QPLFRTAPDYPMSYARQAKNGWVQLKFTVDEHGFVKNTEILASKGGALFEKESIEALNKW 344 + L R P YP G V++KF V G V N +IL++K +FE+E A+ +W Sbjct: 158 RALSRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRW 217 Query: 345 RYAPKFENGKAVEAQTSVQMDYTIN 369 RY P V V + + IN Sbjct: 218 RYEPGKPGSGIV-----VNILFKIN 237
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 56.0 bits (135), Expect = 1e-10 Identities = 31/220 (14%), Positives = 71/220 (32%), Gaps = 25/220 (11%) Query: 80 FELAVSHAKLALEQVRQDNAELDASLLAAKAEVNASATTAQQKRREAKRLDALYVTHGVS 139 + S + Q + + A L A +N ++ ++ +L ++ Sbjct: 191 IKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIA 250 Query: 140 -------QQLRDQADSDAAAAEANLLAANARLEKLKVSRGFYGED------------NLR 180 + +A ++ ++ L + + K + Sbjct: 251 KHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDN 310 Query: 181 VRQAMNALAQAELNLSYTQIRADQDGVVTNLQL-EVGSFAAVGQPLLALV--SDKLDIIA 237 + LA+ E + IRA V L++ G + L+ +V D L++ A Sbjct: 311 IGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTA 370 Query: 238 DFREKTLRGVNAAYPALIAFDGEPGRLYH---AQVSSVDA 274 + K + +N A+I + P Y +V +++ Sbjct: 371 LVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINL 410 Score = 54.8 bits (132), Expect = 2e-10 Identities = 31/197 (15%), Positives = 66/197 (33%), Gaps = 18/197 (9%) Query: 1 MTPDQQFARLVKIAMLGFVAV-FGYFMFADTMMPLTPQAMATRVVT------KVTPQISG 53 TP + RLV ++GF+ + F + + A A +T ++ P + Sbjct: 50 ETPVSRRPRLVAYFIMGFLVIAFILSVLG----QVEIVATANGKLTHSGRSKEIKPIENS 105 Query: 54 KIQSINVNNNQVVAKGDLLFQVDPAPFELAVSHAKLALEQVRQDNAELDASLLAA-KAEV 112 ++ I V + V KGD+L ++ E + +L Q R + + ++ Sbjct: 106 IVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKL 165 Query: 113 NASATTAQQKRREAKRLDALYVTHGVSQQL------RDQADSDAAAAEANLLAANARLEK 166 + + + L +T + +Q + Q + + A L AR+ + Sbjct: 166 PELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINR 225 Query: 167 LKVSRGFYGEDNLRVRQ 183 + Sbjct: 226 YENLSRVEKSRLDDFSS 242
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 27.1 bits (59), Expect = 0.013 Identities = 10/37 (27%), Positives = 18/37 (48%) Query: 37 PPLLSPTPENPLFALRLTFTKALRKLSNKLLVNNKKV 73 P + P + + AL++ + KLL+N KK+ Sbjct: 105 GPAKNLAPLDVINRSLTIVGNALQQKNQKLLLNQKKI 141
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 274 bits (703), Expect = 8e-90 Identities = 117/447 (26%), Positives = 209/447 (46%), Gaps = 14/447 (3%) Query: 8 HRSLPEHEFTQAIEAPAEKRIIKQ---ITYFIAGSVFIMFVWSLFTNIEEIAKAKGQVIP 64 R E+EF A E + ++ + YFI G + I F+ S+ +E +A A G++ Sbjct: 33 VREKDENEFLPAHLELIETPVSRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTH 92 Query: 65 LGHQQVIQSFSGGTLASILVSEGDLVKKGDVLANFIAIDSQAAAEELESKQANLVLKIER 124 G + I+ + I+V EG+ V+KGDVL A+ ++A + +S L+ R Sbjct: 93 SGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTR 152 Query: 125 YSAFIESREANFASYLESHPNLVKGHISDLERM----------NNEKQAIIQSSLAEIAK 174 Y S E N L+ ++S+ E + + + Q L + K Sbjct: 153 YQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELN-LDK 211 Query: 175 SKAELASLDQEIPPLKHQITSAQQTINMMESIKESQAVSKLTMLESQQKLDSYIRELKSM 234 +AE ++ I ++ + ++ S+ QA++K +LE + K + EL+ Sbjct: 212 KRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVY 271 Query: 235 EGKQQVLARDIENLQRQLEQKQATLLKEVGEARTDAQAELLGITARLKSSDSQVQQNTIT 294 + + + + +I + + + + E+ + + +T L ++ + Q + I Sbjct: 272 KSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIR 331 Query: 295 SPVDGIIQSIPNTSSGSVIQPGGTVAVIVPTTPTALLEAKLSPRDIGFVSVGQKARIKID 354 +PV +Q + + G V+ T+ VIVP T + A + +DIGF++VGQ A IK++ Sbjct: 332 APVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVE 391 Query: 355 AFDYSRYGALDGIVKRISPSTDADEKGGVFYKVQISIDKPYFGDQPDKLELIPGMTGEAD 414 AF Y+RYG L G VK I+ D++ G+ + V ISI++ + L GM A+ Sbjct: 392 AFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAE 451 Query: 415 IVTGDKTVFQYLWKPVFTNVTEAFGER 441 I TG ++V YL P+ +VTE+ ER Sbjct: 452 IKTGMRSVISYLLSPLEESVTESLRER 478
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 37.4 bits (86), Expect = 0.002 Identities = 37/197 (18%), Positives = 67/197 (34%), Gaps = 31/197 (15%) Query: 2116 TFSSAQSVDGFTLNADG---SYSFD-----PSHASYQHLAAGQTQTLTIPVTVTDSEGAT 2167 F +S D DG +Y +D S+ + +T + +TVTD+ G Sbjct: 792 NFDGTESKD-----EDGEIKAYEWDFGDGEKSNEAKATHKYNKTGEYEVKLTVTDNNGGI 846 Query: 2168 STQNLTIRLTGTNDAPHI------SGADVGRVVEDQTLSVSGKLAISDADDGQAHFIAQT 2221 +T++ I++ I + + + + V G L+ D D +A+ Sbjct: 847 NTESKKIKVVEDKPVEVINESEPNNDFEKANQIAKSNMLVKGTLSEEDYSDKYYFDVAKK 906 Query: 2222 ATTGSYGSLTIGEDGQWQ---------YQLDNTKPEVQALKSTETATDT---FTVHSADG 2269 + W Y L T + LK +T +V++ D Sbjct: 907 GNVKITLNNLNSVGITWTLYKEGDLNNYVLYATGNDGTVLKGEKTLEPGRYYLSVYTYDN 966 Query: 2270 SSHNITITIQGQRDNVV 2286 S T+ ++G N V Sbjct: 967 QSGTYTVNVKGNLKNEV 983
>PF02370#M protein repeat Length = 168 Score = 31.6 bits (71), Expect = 0.005 Identities = 13/69 (18%), Positives = 32/69 (46%) Query: 388 DERKAKQRIQQEALKQAQKIRSAREEALKVEAETNERLEQKVQERTLELEITLRELHEVN 447 D RK + + Q + + ++ + +E + E + ++ QE+ + + ++L Sbjct: 59 DLRKREGQYQDKIEELEKERKEKQERPERREKFERQHQDKHYQEQQKKHQQEQQQLEAEK 118 Query: 448 QKLTEQSTI 456 QKL ++ I Sbjct: 119 QKLAKEKQI 127
>SECA#SecA protein signature. Length = 901 Score = 1324 bits (3429), Expect = 0.0 Identities = 660/907 (72%), Positives = 767/907 (84%), Gaps = 7/907 (0%) Query: 1 MFGKLLTKVFGSRNDRTLKGLQKVVNKINALEADYEKLTDEQLKAKTAEFRERLAAGASL 60 M KLLTKVFGSRNDRTL+ ++KVVN INA+E + EKL+DE+LK KTAEFR RL G L Sbjct: 1 MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVL 60 Query: 61 DSIMAEAFATVREASKRVFEMRHFDVQLLGGMVLDSNRIAEMRTGEGKTLTATLPAYLNA 120 ++++ EAFA VREASKRVF MRHFDVQLLGGMVL+ IAEMRTGEGKTLTATLPAYLNA Sbjct: 61 ENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNA 120 Query: 121 LTGKGVHVITVNDYLARRDAENNRPLFEFLGLTVGINVAGLGQQDKKDAYNADITYGTNN 180 LTGKGVHV+TVNDYLA+RDAENNRPLFEFLGLTVGIN+ G+ K++AY ADITYGTNN Sbjct: 121 LTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNN 180 Query: 181 EFGFDYLRDNMAFSPQERVQRPLHYALIDEVDSILIDEARTPLIISGAAEDSSELYIKIN 240 E+GFDYLRDNMAFSP+ERVQR LHYAL+DEVDSILIDEARTPLIISG AEDSSE+Y ++N Sbjct: 181 EYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVN 240 Query: 241 TLIPNLIRQDKEDSEEYVGEGDYTIDEKAKQVHFTERGQEKVENLLIERGMLAEGDSLYS 300 +IP+LIRQ+KEDSE + GEG +++DEK++QV+ TERG +E LL++ G++ EG+SLYS Sbjct: 241 KIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYS 300 Query: 301 AANISLLHHVNAALRAHTLFERDVDYIVQDGEVIIVDEHTGRTMPGRRWSEGLHQAVEAK 360 ANI L+HHV AALRAH LF RDVDYIV+DGEVIIVDEHTGRTM GRRWS+GLHQAVEAK Sbjct: 301 PANIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAK 360 Query: 361 EGVRIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFQHIYGLDTVVVPTNRPMVR 420 EGV+IQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEF IY LDTVVVPTNRPM+R Sbjct: 361 EGVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIR 420 Query: 421 KDMADLVYLTANEKYQAIIKDIKDCRERGQPVLVGTVSIEQSELLARLMVKEKIPHQVLN 480 KD+ DLVY+T EK QAII+DIK+ +GQPVLVGT+SIE+SEL++ + K I H VLN Sbjct: 421 KDLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLN 480 Query: 481 AKFHEKEAEIVAQAGRTGAVTIATNMAGRGTDIVLGGNWNMEIDALENPTPEQKAKIKAD 540 AKFH EA IVAQAG AVTIATNMAGRGTDIVLGG+W E+ ALENPT EQ KIKAD Sbjct: 481 AKFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKAD 540 Query: 541 WQLRHDAVVAAGGLHILGTERHESRRIDNQLRGRAGRQGDAGSSRFYLSMEDSLMRIFAS 600 WQ+RHDAV+ AGGLHI+GTERHESRRIDNQLRGR+GRQGDAGSSRFYLSMED+LMRIFAS Sbjct: 541 WQVRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFAS 600 Query: 601 DRVSGMMKKLGMEEGEAIEHPWVSRAIENAQRKVEARNFDIRKQLLEFDDVANDQRQVVY 660 DRVSGMM+KLGM+ GEAIEHPWV++AI NAQRKVE+RNFDIRKQLLE+DDVANDQR+ +Y Sbjct: 601 DRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIY 660 Query: 661 AQRNELMDAESIADTIQNIQDDVISAVIDQYIPPQSVEELWDVPGLEQRLHQEFMLKLPI 720 +QRNEL+D +++TI +I++DV A ID YIPPQS+EE+WD+PGL++RL +F L LPI Sbjct: 661 SQRNELLDVSDVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPI 720 Query: 721 QEWLDKEDDLHEESLRERIITSWSDAYKAKEEMVGASVLRQFEKAVMLQTLDGLWKEHLA 780 EWLDKE +LHEE+LRERI+ + Y+ KEE+VGA ++R FEK VMLQTLD LWKEHLA Sbjct: 721 AEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLA 780 Query: 781 AMDHLRQGIHLRGYAQKNPKQEYKRESFELFQQLLNTLKHDVISVLSKVQVQAQSDVEEM 840 AMD+LRQGIHLRGYAQK+PKQEYKRESF +F +L +LK++VIS LSKVQV+ +VEE+ Sbjct: 781 AMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEEL 840 Query: 841 EARRREEDAKIQRDYQHAAAEALVGGSDEDDAIAAHTPMIRDGDKVGRNDPCPCGSGRKY 900 E +RR E A + D+D A AA KVGRNDPCPCGSG+KY Sbjct: 841 EQQRRMEAE-------RLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKY 893 Query: 901 KQCHGKL 907 KQCHG+L Sbjct: 894 KQCHGRL 900
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 68.6 bits (168), Expect = 6e-15 Identities = 51/221 (23%), Positives = 91/221 (41%), Gaps = 20/221 (9%) Query: 150 SGMRMEAKVHIVTC----ANDMAKNITK-SVERCGLKVDDLVFSGIASADAVLTFDEKDL 204 S M ++ C A + + + S + G + L+ +A+A + Sbjct: 100 SNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEAT 159 Query: 205 GVCIVDIGGGTTDIAVYTNGALRHCAVVPVAGNQVTNDIAKIFR------TPSSHAEQIK 258 G +VDIGGGTT++AV + + + + V + G++ I R + AE+IK Sbjct: 160 GSMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIK 219 Query: 259 VQFACARSSMVSREDSIEVPS---VGGRPSR-SMSRHTLAEVVEPRYQELFELVLKELKD 314 + A IEV G P +++ + + E ++ + V+ L+ Sbjct: 220 HEIGSAYPG--DEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQ 277 Query: 315 SGLE---DQIAAGIVLTGGTASIQGVVDIAEATFGMPVRVA 352 E D G+VLTGG A ++ + + G+PV VA Sbjct: 278 CPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVA 318
>LIPPROTEIN48#Mycoplasma P48 major surface lipoprotein signature. Length = 428 Score = 28.8 bits (64), Expect = 0.033 Identities = 24/125 (19%), Positives = 42/125 (33%), Gaps = 25/125 (20%) Query: 111 GVAAKLAGVPLVLHEQNAIPGMTNKLLSRIASQVLCAFKNTFTQVKAKVVGNPIRRELIA 170 G++ A +P V G ++ + + + T K V Sbjct: 10 GLSPIAAILPAVA----VSCGNNDESNISFKEKDISKYTTTNANGKQVV----------- 54 Query: 171 LGGEPKQTADEALKVLVV--GGSLGAKVFNDLMPEVVAALSKQQSITVWHQVGKDNLAGV 228 K LK +++ G + K FN E + A++KQ I + + N Sbjct: 55 -----KNAELLKLKPVLITDEGKIDDKSFNQSAFEALKAINKQTGIEINNVEPSSNF--- 106 Query: 229 KSAYQ 233 +SAY Sbjct: 107 ESAYN 111
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 58.0 bits (140), Expect = 7e-12 Identities = 28/121 (23%), Positives = 55/121 (45%), Gaps = 16/121 (13%) Query: 154 NNTFFASGSAFIQPKFIPLIDKIGEVIASV---PGRVVIAGHTDATLPMEIYADNWDLSS 210 ++ F A ++P+ +D++ ++++ G VV+ G+TD N LS Sbjct: 219 SDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAY---NQGLSE 275 Query: 211 LRATAVVRIMTKNKGVNPSRIIVQGLADTQPRFQNDTPEHRQK---------NRRIEIIL 261 RA +VV + KG+ +I +G+ ++ P N +Q+ +RR+EI + Sbjct: 276 RRAQSVVDYLIS-KGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEV 334 Query: 262 N 262 Sbjct: 335 K 335
>CABNDNGRPT#NodO calcium binding signature. Length = 479 Score = 74.6 bits (183), Expect = 2e-15 Identities = 40/124 (32%), Positives = 55/124 (44%), Gaps = 9/124 (7%) Query: 2580 DTVNLGSGDDTVNGGQGSQLVYGGSGDDLLIGGEGIDGLRGGDGNDTLIGGLGDDVLRGD 2639 ++ G + GG G+ ++ G S D++L GG G D L GG G DTL GG G D Sbjct: 332 VSIAHGVTIENAIGGSGNDILVGNSADNILQGGAGNDVLYGGAGADTLYGGAGRDTFVYG 391 Query: 2640 SGADTFVWRYADADKGTDHIMDFKVGEDKLDLSDLLQGETANTLESYLKFSLNNGSTVID 2699 SG D+ V D I DF+ G DK+DLS +F+ ++ Sbjct: 392 SGQDSTV-------AAYDWIADFQKGIDKIDLSAF--RNEGQLSFVQDQFTGKGQEVMLQ 442 Query: 2700 IDAN 2703 DA Sbjct: 443 WDAA 446
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 29.5 bits (66), Expect = 0.017 Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 6/83 (7%) Query: 67 MMGGMLGGLLAGGLLAALFMGEGFENIQFMDILIIALLAFVLFKIVRTVMASKASAQPRP 126 + G+ L+ L A F+ E FM I+I+ +L + F +TV+++ S+ + Sbjct: 326 LNIGVT--FLSVSFLTASFLLET--TSWFMTIIIVFVLGGLSF--TKTVISTIVSSSLKQ 379 Query: 127 AYAGAGQPNPNLQRQQAEQTGFA 149 AGAG N +E TG A Sbjct: 380 QEAGAGMSLLNFTSFLSEGTGIA 402
>PF03627#PapG Length = 336 Score = 27.6 bits (61), Expect = 0.037 Identities = 9/26 (34%), Positives = 15/26 (57%) Query: 41 TYEYCGGNWTADGQGAYHQDVFAYYI 66 T+ C G ADG AY+++ A+ + Sbjct: 60 TWNQCNGPGFADGSWAYYREYIAWVV 85
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 31.0 bits (70), Expect = 0.016 Identities = 11/64 (17%), Positives = 29/64 (45%), Gaps = 3/64 (4%) Query: 567 DYRYSESDSQSRIQPRASADY---FNFTHQFDISLNYELSKSDSLSLSYRYERYFDTDAA 623 Y D +++P+ + Y +N + +++ +L ++ +L LS ++ Y+ T Sbjct: 499 GYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSNV 558 Query: 624 NVDI 627 + Sbjct: 559 DEQF 562
>SECA#SecA protein signature. Length = 901 Score = 40.2 bits (94), Expect = 3e-05 Identities = 31/84 (36%), Positives = 39/84 (46%), Gaps = 8/84 (9%) Query: 289 MRLVQGDV-----GSGKTLVAALAA-LQAIENGYQVAMMAPTELLAEQHAANFAAWFEPL 342 M L + + G GKTL A L A L A+ G V ++ + LA++ A N FE L Sbjct: 92 MVLNERCIAEMRTGEGKTLTATLPAYLNALT-GKGVHVVTVNDYLAQRDAENNRPLFEFL 150 Query: 343 GLKVGW-LAGKLKGKARAQSLADI 365 GL VG L G R ADI Sbjct: 151 GLTVGINLPGMPAPAKREAYAADI 174
>FRAGILYSIN#Fragilysin metallopeptidase (M10C) enterotoxin signature. Length = 405 Score = 25.0 bits (54), Expect = 0.033 Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 4/74 (5%) Query: 1 MQNREQILAMLTTILVDEFEIDADAITP--DANLYEELDLDSIDAVDLVIKLQQL--TGK 56 M+N + +L + T L+ +AD++T DA + +DL S+ DL +L + GK Sbjct: 9 MKNVKLLLMLGTAALLAACSNEADSLTTSIDAPVTASIDLQSVSYTDLATQLNDVSDFGK 68 Query: 57 KIQPDEFKSVRTVN 70 I + R V+ Sbjct: 69 MIILKDNGFNRQVH 82
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 36.0 bits (83), Expect = 7e-04 Identities = 26/147 (17%), Positives = 52/147 (35%), Gaps = 21/147 (14%) Query: 689 LLGLALVIALLLFSLSFGLKKATVVVAVPALAAVLTLAILGLVGSPLSLFHALALILIFG 748 + LV ++ L +AVP + + T AIL G ++ ++L G Sbjct: 345 FEAIMLVFLVMYLFLQNMRATLIPTIAVP-VVLLGTFAILAAFGYSINTLTMFGMVLAIG 403 Query: 749 IGIDYSL----------------FFASVEQHGKAVMMAVFMSACSTLLAFGLLAFSQTQA 792 + +D ++ + E+ + A+ A F +AF Sbjct: 404 LLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGST 463 Query: 793 ---IHYFGLTLSLGIGFTFVLSPLILT 816 F +T+ + + +++ LILT Sbjct: 464 GAIYRQFSITIVSAMALSVLVA-LILT 489 Score = 34.4 bits (79), Expect = 0.002 Identities = 35/195 (17%), Positives = 72/195 (36%), Gaps = 18/195 (9%) Query: 276 LGLASLLGVVLLVWLAFRSVMPLLLAIVTISSGLLLAVTFTLSVFGELHLLTLVFGTSLI 335 L A +L V L+++L +++ L+ + + LL + ++ LT+ I Sbjct: 344 LFEAIML-VFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAI 402 Query: 336 GIAIDYSFHFY--CERLNEQHHSAQATVAYI------FPTVSLAFITSALAYVGIGLAPF 387 G+ +D + ER+ + V +A + SA V I +A F Sbjct: 403 GLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSA---VFIPMAFF 459 Query: 388 PG-----MQQVAIFCASGLLGAYLTLVLAYPLLAGSKL-PSGEQPLNLAQAYLARMAQFS 441 G +Q +I S + + L ++ P L + L P + + Sbjct: 460 GGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTF 519 Query: 442 NKLVSPWGLSLFTLI 456 + V+ + S+ ++ Sbjct: 520 DHSVNHYTNSVGKIL 534 Score = 34.0 bits (78), Expect = 0.003 Identities = 23/117 (19%), Positives = 43/117 (36%), Gaps = 17/117 (14%) Query: 689 LLGLA-LVIALLLFSLSFGLKKATVVVAVPALAAVLTLAILGLVGSPLSLFHALALILIF 747 L+ ++ +V+ L L +L V+ V L V L L ++ + L+ Sbjct: 875 LVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTI 934 Query: 748 GIGIDYSLFFASV-----EQHGKAVMMAV-----------FMSACSTLLAFGLLAFS 788 G+ ++ E+ GK V+ A M++ + +L LA S Sbjct: 935 GLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAIS 991
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 107 bits (267), Expect = 3e-30 Identities = 71/248 (28%), Positives = 114/248 (45%), Gaps = 15/248 (6%) Query: 5 VLVTGSSRGIGKAIALKLAAAGHDIALHYHSNQAAADASAAELRALGVNVSLLKFDVADR 64 +TG+++GIG+A+A LA+ G IA N + + L+A + DV D Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIA-AVDYNPEKLEKVVSSLKAEARHAEAFPADVRDS 69 Query: 65 VAVRAALEADIEANGAYYGVVLNAGINRDNAFPAMSEAEWDSVIHTNLDGFYNVIHPCVM 124 A+ G +V AG+ R ++S+ EW++ N G +N V Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS-VS 128 Query: 125 PMVQARKGGRIITLASVSGIAGNRGQVNYSASKAGLIGATKALSLELAKRKITVNCIAPG 184 + R+ G I+T+ S Y++SKA + TK L LELA+ I N ++PG Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 185 LIETDM----------VADIPKDMVEQL---VPMRRMGKPNEIAALAAFLMSDDAAYITR 231 ETDM + K +E +P++++ KP++IA FL+S A +IT Sbjct: 189 STETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITM 248 Query: 232 QVISVNGG 239 + V+GG Sbjct: 249 HNLCVDGG 256
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 102 bits (255), Expect = 2e-27 Identities = 38/128 (29%), Positives = 60/128 (46%), Gaps = 4/128 (3%) Query: 2 KILIAEDDIHIRQGLADMLSREGYSVLLADNGKVALLKYQQEQPDFIILDIMMPELDGYS 61 IL+A+DD IR L LSR GY V + N D ++ D++MP+ + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VCKEIRKHDEQTPVIFLSAKGEELDKVLGLELGADDYINKPFGIHEVRARIKTIARRCLK 121 + I+K PV+ +SA+ + + E GA DY+ KPF + E+ I R L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGII----GRALA 120 Query: 122 AKQNSPDQ 129 + P + Sbjct: 121 EPKRRPSK 128
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 37.6 bits (87), Expect = 6e-06 Identities = 21/80 (26%), Positives = 34/80 (42%), Gaps = 2/80 (2%) Query: 61 DRNLAGCGALKWLDAEHAEIKSMRTAATYKQQGVASQILQHLINDAKAAGVQRLSLETGS 120 + N G ++ +A I+ + A Y+++GV + +L I AK L LET Sbjct: 73 ENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQD 132 Query: 121 MTFFQPARSLYAKFGFELCG 140 + A YAK F + Sbjct: 133 INI--SACHFYAKHHFIIGA 150
>cdtoxinb#Cytolethal distending toxin B signature. Length = 269 Score = 27.7 bits (61), Expect = 0.034 Identities = 16/53 (30%), Positives = 25/53 (47%), Gaps = 1/53 (1%) Query: 1 MSKVLVLKSSILGGYSQSALLVDYLIGKWEKQGATITVRDLAGKDVLPMVDGE 53 M K ++ L Y+Q A L D+ + W QGA+ T +V ++ GE Sbjct: 1 MKKYIISLIVFLSFYAQ-ADLTDFRVATWNLQGASATTESKWNINVRQLISGE 52
>PF07201#Hypersensitivity response secretion protein HrpJ Length = 293 Score = 28.3 bits (63), Expect = 0.040 Identities = 19/92 (20%), Positives = 37/92 (40%), Gaps = 6/92 (6%) Query: 50 LGVSLSLPAA-LQVLVKNAETITSSWNSAAEISL-----FIDENRSEQTIQSLLTRIRTY 103 G S+ + + LQ + AE +T ++ E+SL + R + + + Sbjct: 35 RGESVQIVSGTLQSIADMAEEVTFVFSERKELSLDKRKLSDSQARVSDVEEQVNQYLSKV 94 Query: 104 PEVEKVQYIDRNQALEEFQRLSGFGEALAYLD 135 PE+E+ Q + +L + AYL+ Sbjct: 95 PELEQKQNVSELLSLLSNSPNISLSQLKAYLE 126
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 57.8 bits (139), Expect = 8e-11 Identities = 38/198 (19%), Positives = 70/198 (35%), Gaps = 14/198 (7%) Query: 17 DEVVEQTPV-VTPS-QTEQDEALAEQQAEAAR---------LAAEKIAAENAEAERIAAE 65 DE P TPS TE ++Q+++ A + A+ A++ A Sbjct: 1021 DEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANT 1080 Query: 66 QATKAQVEALRLAEAEEQAIKAQAAAERFVEQQAAETARLAAEQALAAQLAAEKAESERI 125 Q + E + K A E+ E+ ET + + +Q++ ++ +SE + Sbjct: 1081 QTNEVAQSGSETKETQTTETKETATVEK-EEKAKVETEKTQEVPKVTSQVSPKQEQSETV 1139 Query: 126 ATEQAAKAQAEVEALRLAEEQAEVARLAEQ-QAAEATRLAAEQALAEQLAAEKAEAEQIQ 184 QA A+ + + E Q++ A+ Q A+ T EQ + E + Sbjct: 1140 -QPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVEN 1198 Query: 185 VEQPLEQQPEPQAKPAKE 202 E +P Sbjct: 1199 PENTTPATTQPTVNSESS 1216 Score = 53.9 bits (129), Expect = 1e-09 Identities = 33/194 (17%), Positives = 71/194 (36%), Gaps = 40/194 (20%) Query: 17 DEVVEQTPVVTPSQTEQDEALAEQQAEAARLAAEKI-------AAENAEAERIAAEQATK 69 ++ V+ T + TP+ + D + ++ A + E +A + Sbjct: 989 NQTVDTTNITTPNNIQADVP-SVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQE 1047 Query: 70 AQVEALRLAEAEEQAIKAQAAAERFVEQQAAETARLAAEQALAAQLAAEKAESERIATEQ 129 ++ +A E + + A+ +A + + AQ +E E++ T++ Sbjct: 1048 SKTVEKNEQDATETTAQNREVAK-----EAKSNVKANTQTNEVAQSGSETKETQTTETKE 1102 Query: 130 AAKAQAEVEALRLAEEQAEVARLAEQQAAEATRLAAEQALAEQLAAEKAEAEQIQVEQPL 189 A + E +A E+ EV ++ Q + + E++E Q Sbjct: 1103 TATVEKEEKAKVETEKTQEVPKVTSQVSPKQ---------------EQSETVQ------- 1140 Query: 190 EQQPEPQAKPAKES 203 PQA+PA+E+ Sbjct: 1141 -----PQAEPAREN 1149
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 75.3 bits (185), Expect = 6e-18 Identities = 29/124 (23%), Positives = 61/124 (49%), Gaps = 1/124 (0%) Query: 3 VLLVEDNRLLSNNIIQYLELSGIECDYAFNLAQAEMLISQQQFDAIILDLNLPDGDGIEA 62 +L+ +D+ + + Q L +G + N A I+ D ++ D+ +PD + + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 63 CERWKAQCFSSPIIMLTARSSLNERLAGFAVGADDYLIKPFAMEELVARL-KVVAQRRPA 121 R K P+++++A+++ + GA DYL KPF + EL+ + + +A+ + Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRR 125 Query: 122 PQRL 125 P +L Sbjct: 126 PSKL 129
>56KDTSANTIGN#Rickettsia 56kDa type-specific antigen protein signature. Length = 533 Score = 33.0 bits (75), Expect = 5e-04 Identities = 15/34 (44%), Positives = 17/34 (50%) Query: 73 QQKQQQQQSSQQQSQQQQEKHAPAVAAERALPKN 106 Q QQQQ QQQ Q + A A AA R L + Sbjct: 338 PQAQQQQGQGQQQQAQATAQEAVAAAAVRLLNGS 371 Score = 28.0 bits (62), Expect = 0.021 Identities = 10/33 (30%), Positives = 14/33 (42%) Query: 70 QQVQQKQQQQQSSQQQSQQQQEKHAPAVAAERA 102 Q+ +QQQ Q Q++ A A A E Sbjct: 328 NQIHLNFVMPPQAQQQQGQGQQQQAQATAQEAV 360
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 101 bits (252), Expect = 9e-27 Identities = 46/175 (26%), Positives = 84/175 (48%), Gaps = 4/175 (2%) Query: 6 SKILVVDDDMRLRALLERYLMEQGYQVRSAANAEQMDRLLERENFHLIVLDLMLPGEDGL 65 + ILV DDD +R +L + L GY VR +NA + R + + L+V D+++P E+ Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 66 SICRRLRQQGSTIPIVMLTAKGDEVDRIIGLELGADDYLPKPFNPRELLARI-KAVMRRQ 124 + R+++ +P+++++A+ + I E GA DYLPKPF+ EL+ I +A+ + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 125 TQDVPGAPAQQEAEIRFGEFSLDLATREMYH---GDEAIVLTSGEFAVLKVLVTH 176 + Q+ G + + + ++ +GE K LV Sbjct: 124 RRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVAR 178
>PF06580#Sensor histidine kinase Length = 349 Score = 46.0 bits (109), Expect = 1e-07 Identities = 19/120 (15%), Positives = 40/120 (33%), Gaps = 24/120 (20%) Query: 325 DCPEALFQGLAIKRVLSNLVENAFRYG------SGWVRISSQFDGKRIGFSVEDNGPGID 378 A+ ++ LVEN ++G G + + D + VE+ G Sbjct: 245 QINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLAL 304 Query: 379 ESQIPTLFQPFTQGDIARGSVGSGLGLA-IIKRIIDRHQGQITLS-NRAAGGLKAQVWLP 436 ++ +G GL + +R+ + + + + G + A V +P Sbjct: 305 KNTKE----------------STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 76.8 bits (189), Expect = 2e-18 Identities = 30/168 (17%), Positives = 68/168 (40%), Gaps = 13/168 (7%) Query: 2 KVLIVDDNHDVIETIMDYLTLEGIIADCAYHGESAINLIQQNHYDVIIMDIMMPKLDGIR 61 +L+ DD+ + + L+ G + + I D+++ D++MP + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 TVKKLREELFCNTPILFLTARDSLQDKIDSFTSGGDDFLNKPF------AMEELCLRLRS 115 + ++++ + P+L ++A+++ I + G D+L KPF + L Sbjct: 65 LLPRIKKAR-PDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 116 LHNRGPRLDVGILRFGEISLNVATQQACRAGKEIKLSKIQRTILTLLL 163 D + + A Q+ R L+++ +T LTL++ Sbjct: 124 R-RPSKLEDDSQDGMPLVGRSAAMQEIYR-----VLARLMQTDLTLMI 165
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 179 bits (456), Expect = 4e-57 Identities = 69/286 (24%), Positives = 132/286 (46%), Gaps = 33/286 (11%) Query: 17 KPLSQVVFWCGFILSLLLAAQITWKLVPTSSSPTAWSPSAVTTTGKGAGQIDLDGLQQLA 76 + +++F+ +L A I W++ ++P S+V T A Q + L Sbjct: 12 SVIRRILFYLLMLLFCQQLAMIFWRIGLPDNAPV----SSVQITPAQARQQPV-TLNDFT 66 Query: 77 LFGRADAKTDKPKAEVVETVTDAPKTSLSIQLTGVVASTADQKGLAIIESSGSQETYSLG 136 LFG + K + +++ P ++L++ LTGV+A D + +AII Q + + Sbjct: 67 LFGVSPEKNKAGALDA-SQMSNLPPSTLNLSLTGVMAGDDDSRSIAIISKDNEQFSRGVN 125 Query: 137 DKIKGTSASLKEVYADRIIITNAGRYETLMLDGLVYTSQSPANQQLQKAKSGKPEVVSRV 196 +++ G +A + + DR+++ GRYE L L + Sbjct: 126 EEVPGYNAKIVSIRPDRVVLQYQGRYEVLGLYSQEDSGSDGVPG---------------- 169 Query: 197 DQRKNAEISQELAESRTELLADPSKITDYIAISPVKQGESVVGYRLNPGKDVNLFKQAGF 256 A+++++L + + ++DY++ SP+ + GYRLNPG + F + G Sbjct: 170 -----AQVNEQLQQR------ASTTMSDYVSFSPIMNDNKLQGYRLNPGPKSDSFYRVGL 218 Query: 257 KPNDLAKTINGYDLTVMSQALEMMSQLPELTEVSIMVEREGQLVEI 302 + ND+A +NG DL QA + M ++ ++ ++ VER+GQ +I Sbjct: 219 QDNDMAVALNGLDLRDAEQAKKAMERMADVHNFTLTVERDGQRQDI 264
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 593 bits (1529), Expect = 0.0 Identities = 325/681 (47%), Positives = 448/681 (65%), Gaps = 33/681 (4%) Query: 6 IRRKLIAGVVAGATMLTSQFVWSEQYAANFKGTDIQEFINIVGKNLNKTIIVDPTIRGKI 65 IR + ++ A + +E+++A+FKGTDIQEFIN V KNLNKT+I+DP++RG I Sbjct: 7 IRSFSLTLLIFAALLFRP--AAAEEFSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTI 64 Query: 66 NVRSYDLLNDEQYYQFFLNVLQVYGYAIVEMENNVIKVIKDKDAKTAAIRVANDNDPGLG 125 VRSYD+LN+EQYYQFFL+VL VYG+A++ M N V+KV++ KDAKTAA+ VA+D PG+G Sbjct: 65 TVRSYDMLNEEQYYQFFLSVLDVYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIG 124 Query: 126 DEMVTRIVALYNTEAKQLAPLLRQLNDNAGGGNVVNYDPSNVLMLSGRAAVVNKLVEIIR 185 DE+VTR+V L N A+ LAPLLRQLNDNAG G+VV+Y+PSNVL+++GRAAV+ +L+ I+ Sbjct: 125 DEVVTRVVPLTNVAARDLAPLLRQLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVE 184 Query: 186 RVDKQGDTSVQVVPLEYASAGEMVRIIDTLYRATANQSQLPGQAPKVVADERINAVVVSG 245 RVD GD SV VPL +ASA ++V+++ L + T+ + VVADER NAV+VSG Sbjct: 185 RVDNAGDRSVVTVPLSWASAADVVKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSG 244 Query: 246 DEKSRQRVVELIHRLDAEQASTGNTKVRYLRYAKAEDLVEVLTGFAQKLESEKDPSAQAA 305 + SRQR++ +I +LD +QA+ GNTKV YL+YAKA DLVEVLTG + ++SEK A Sbjct: 245 EPNSRQRIIAMIKQLDRQQATQGNTKVIYLKYAKASDLVEVLTGISSTMQSEK---QAAK 301 Query: 306 GGGKRRNEINIMAHTDTNALVISAEPDQMRTIESVINQLDIRRAQVLVEAIIVEVAEGDN 365 I I AH TNAL+++A PD M +E VI QLDIRR QVLVEAII EV + D Sbjct: 302 PVAALDKNIIIKAHGQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADG 361 Query: 366 VGFGVQWAAKAGGGTQFNNLGPTIGEIGAGIWQAQDKEGTYITNPSTGEVIGQNPKTKGD 425 + G+QWA K G TQF N G I AG Q +K+GT ++ Sbjct: 362 LNLGIQWANKNAGMTQFTNSGLPISTAIAGANQ-YNKDGTVSSS---------------- 404 Query: 426 VTLLAQALGKVNGMAWGVAMGDFGALVQAVSADTNSNVLATPSITTLDNQEASFIVGDEV 485 LA AL NG+A G G++ L+ A+S+ T +++LATPSI TLDN EA+F VG EV Sbjct: 405 ---LASALSSFNGIAAGFYQGNWAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEV 461 Query: 486 PILTGSTASSNNSNPFQTVERKEVGVKLKVVPQINEGNAVKLAIEQEVSGVNG-----NT 540 P+LTGS +++ N F TVERK VG+KLKV PQINEG++V L IEQEVS V ++ Sbjct: 462 PVLTGSQ-TTSGDNIFNTVERKTVGIKLKVKPQINEGDSVLLEIEQEVSSVADAASSTSS 520 Query: 541 GVDISFATRRLTTTVMADSGQIVVLGGLINEEVQESIQKVPFLGDIPILGHLFKSSSSKK 600 + +F TR + V+ SG+ VV+GGL+++ V ++ KVP LGDIP++G LF+S+S K Sbjct: 521 DLGATFNTRTVNNAVLVGSGETVVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKV 580 Query: 601 TKKNLMIFIKPTIIRDGVTMEGIAGRKYNYFRALQLEQQ-ERGVNLMPDTKVPVLDEWNQ 659 +K+NLM+FI+PT+IRD + +Y F Q +Q+ + + M + + + Q Sbjct: 581 SKRNLMLFIRPTVIRDRDEYRQASSGQYTAFNDAQSKQRGKENNDAMLNQDLLEIYP-RQ 639 Query: 660 SEYLPPEVNDILERYKEGKGL 680 +V+ ++ + G L Sbjct: 640 DTAAFRQVSAAIDAFNLGGNL 660
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 506 bits (1304), Expect = 0.0 Identities = 232/407 (57%), Positives = 308/407 (75%), Gaps = 1/407 (0%) Query: 1 MPAFEYKALDAKGKQLKGVIEADTARHARSQLRDQRLMPLDILPVTEKEAKAKSSGFAL- 59 M + Y+ALDA+GK+ +G EAD+AR AR LR++ L+PL + + K+ S+G +L Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 60 FKRGISVAELALITRQIATLVAAGLPIEESLKAVGQQCEKDRLASMIMAVRSRVVEGYSL 119 K +S ++LAL+TRQ+ATLVAA +P+EE+L AV +Q EK L+ ++ AVRS+V+EG+SL Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 120 ADSLAEFPHIFDDLYRAMVASGEKSGHLEVVLNRLADYTERRQQLKSKLQQAMIYPIMLT 179 AD++ FP F+ LY AMVA+GE SGHL+ VLNRLADYTE+RQQ++S++QQAMIYP +LT Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 180 LVAIGVVSVLLAAVVPKVVGQFEHMGAELPATTRFLIAASDFVQNYGLLVVLVLGILLVV 239 +VAI VVS+LL+ VVPKVV QF HM LP +TR L+ SD V+ +G ++L L + Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMA 240 Query: 240 FQRLLKSPIFKMKFHTFLLKMPVIGRVSKGLNTARFARTLSILSASSVPLLDGMRIASEV 299 F+ +L+ ++ FH LL +P+IGR+++GLNTAR+ARTLSIL+AS+VPLL MRI+ +V Sbjct: 241 FRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 300 LQNMRVRAAVDDATARVREGTSLSTALTNTKLFPAMMLYMIASGEKSGQLEDMLERAADN 359 + N R + AT VREG SL AL T LFP MM +MIASGE+SG+L+ MLERAADN Sbjct: 301 MSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADN 360 Query: 360 QDREFESNVTLALGVFEPMLVVSMAGVVLFIVMAILQPILALNNLIS 406 QDREF S +TLALG+FEP+LVVSMA VVLFIV+AILQPIL LN L+S Sbjct: 361 QDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLMS 407
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 229 bits (586), Expect = 4e-81 Identities = 97/144 (67%), Positives = 118/144 (81%) Query: 1 MQMNKKHKGFTLLEVMVVIVILGILASMVVPNLMGNKDKADQQKAVSDIVALENALDMYK 60 M+ K +GFTLLE+MVVIVI+G+LAS+VVPNLMGNK+KAD+QKAVSDIVALENALDMYK Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK 60 Query: 61 LDNGVYPTTEQGLEALVQKPTISPEPRNYREEGYVKRLPQDPWRNNYLLLSPGENSKLDI 120 LDN YPTT QGLE+LV+ PT+ P NY +EGY+KRLP DPW N+Y+L++PGE+ D+ Sbjct: 61 LDNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDL 120 Query: 121 FSAGPDSQPGTEDDIGNWNLQNFQ 144 SAGPD + GTEDDI NW L + Sbjct: 121 LSAGPDGEMGTEDDITNWGLSKKK 144
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 83.1 bits (205), Expect = 1e-22 Identities = 45/171 (26%), Positives = 71/171 (41%), Gaps = 39/171 (22%) Query: 4 LRHAGFTLMEVMLVILLMGLTAAGVTMSIGNSGPQQALEKTAQQFIAATELVLDETVLSG 63 +R GFTL+E+ML++LLMG++A V ++ S A + T +F A V + +G Sbjct: 1 MRQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQ-TLARFEAQLRFVQQRGLQTG 59 Query: 64 QFIGIVVEKTSYQFVFYKDG---------------KWNPLEKDRILSEKQMEPGVVINLV 108 QF G+ V +QF+ + +W PL R+ + Sbjct: 60 QFFGVSVHPDRWQFLVLEARDGADPAPADDGWSGYRWLPLRAGRVATSGS---------- 109 Query: 109 LDGLPLVQEDEQDESWFEEPLIEPSSEDKKKHPEPQILLFPSGEMSAFELS 159 + G L Q E+W P +L+FP GEM+ F L+ Sbjct: 110 IAGGKLNLAFAQGEAW-------------TPGDNPDVLIFPGGEMTPFRLT 147
>PilS_PF08805#PilS N terminal Length = 185 Score = 30.3 bits (68), Expect = 0.001 Identities = 12/32 (37%), Positives = 18/32 (56%) Query: 5 RGMTLLEVIVALAVFAVAAVSITKSLSEQMAN 36 +G TL+EV++ + V V A S K S +N Sbjct: 26 KGATLMEVLLVVGVIVVLAASAYKLYSMVQSN 57
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 35.6 bits (82), Expect = 5e-05 Identities = 15/40 (37%), Positives = 26/40 (65%), Gaps = 3/40 (7%) Query: 4 KRTNAHRGFTLLEMLIAIAIFAMLGLAANAVLSTVLTNDE 43 + T+ RGFTLLE+++ I I +G+ A+ V+ ++ N E Sbjct: 2 RATDKQRGFTLLEIMVVIVI---IGVLASLVVPNLMGNKE 38
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 42.8 bits (101), Expect = 1e-06 Identities = 32/156 (20%), Positives = 57/156 (36%), Gaps = 34/156 (21%) Query: 199 VDIGANMTTFCVVESGETTFIREQAFGGELFTQSILSFYGMSY------EQAEKAKIE-- 250 VDIG T V+ + GG+ F ++I+++ +Y AE+ K E Sbjct: 164 VDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIG 223 Query: 251 -------------------GDLPRNY------MFEVLSPFQTQLLQQIKRTLQIYCTSSG 285 +PR + + E L T ++ + L+ Sbjct: 224 SAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELA 283 Query: 286 KDKVDY-LVLCGGTSKLEGMANLLTNELGVHTIIAD 320 D + +VL GG + L + LL E G+ ++A+ Sbjct: 284 SDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAE 319
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 247 bits (632), Expect = 8e-75 Identities = 99/411 (24%), Positives = 187/411 (45%), Gaps = 38/411 (9%) Query: 306 GDITLRLDDVPWDQALDLILQTKGLDKRIEGNILMVAPSEELAIRESQNLKNKQEVKELA 365 GD ++ + W A D++ L+K + L + + E N Sbjct: 190 GDRSVVTVPLSWASAADVVKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSGEPNSR 249 Query: 366 PLYSEYLQ----------------INYAKATDIAELLKGADSSLLSPRG----------- 398 ++ + YAKA+D+ E+L G S++ S + Sbjct: 250 QRIIAMIKQLDRQQATQGNTKVIYLKYAKASDLVEVLTGISSTMQSEKQAAKPVAALDKN 309 Query: 399 -SVAVDERTNTVLVKDTAEIIENIHRLVEVLDIPIRQVLIESRMVTVKDDVSEDLGIRWG 457 + +TN ++V +++ ++ R++ LDI QVL+E+ + V+D +LGI+W Sbjct: 310 IIIKAHGQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLGIQWA 369 Query: 458 VTDQQGNKGTSGSLEGAGDIANGKVPSLDNRLNVNLPAAVTNPTSIAFHVAKLADGTILD 517 + + T+ L + IA + D ++ +L +A+++ IA + Sbjct: 370 NKNAGMTQFTNSGLPISTAIAGANQYNKDGTVSSSLASALSSFNGIAAGFYQGN----WA 425 Query: 518 LELSALEQENKGEIIASPRITTSNQKAAYIEQGVEIPYV-----QSTSSGATSVTFKKAV 572 + L+AL K +I+A+P I T + A G E+P + S + +V K Sbjct: 426 MLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVPVLTGSQTTSGDNIFNTVERKTVG 485 Query: 573 LSLRVTPQITPDNRVILDLEITQDSQGKT-VDTPTGPAVAIDTQRIGTQVLVDNGETIVL 631 + L+V PQI + V+L++E S T + +T+ + VLV +GET+V+ Sbjct: 486 IKLKVKPQINEGDSVLLEIEQEVSSVADAASSTSSDLGATFNTRTVNNAVLVGSGETVVV 545 Query: 632 GGIYQQNLISRVSKVPILGDIPLVGFLFRNTTDKNERQELLIFVTPKIVNE 682 GG+ +++ KVP+LGDIP++G LFR+T+ K ++ L++F+ P ++ + Sbjct: 546 GGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRNLMLFIRPTVIRD 596 Score = 47.6 bits (113), Expect = 1e-07 Identities = 34/175 (19%), Positives = 75/175 (42%), Gaps = 14/175 (8%) Query: 275 SLNFQNISVRTVLQIIADYNNFNLVTSDSVEGDITLR-LDDVPWDQALDLILQTKGLDKR 333 S +F+ ++ + ++ N ++ SV G IT+R D + +Q L Sbjct: 31 SASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRSYDMLNEEQYYQFFLSVL----D 86 Query: 334 IEGNILMVAPSEELAIRESQNLKNKQEVK--ELAP-----LYSEYLQINYAKATDIAELL 386 + G ++ + L + S++ K + AP + + + + A D+A LL Sbjct: 87 VYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIGDEVVTRVVPLTNVAARDLAPLL 146 Query: 387 KGADSSLLSPRGSVAVDERTNTVLVKDTAEIIENIHRLVEVLDIPIRQVLIESRM 441 + + + + GSV E +N +L+ A +I+ + +VE +D + ++ + Sbjct: 147 RQLNDN--AGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDNAGDRSVVTVPL 199
>PF05272#Virulence-associated E family protein Length = 892 Score = 31.2 bits (70), Expect = 0.002 Identities = 16/64 (25%), Positives = 25/64 (39%), Gaps = 8/64 (12%) Query: 9 LVGPMGAGKSTIGRHLAQML-----HLEFHDSDQEIEQRTGADIAWVFDVEGEEGFRRRE 63 L G G GKST+ L + H + EQ G +++ FRR + Sbjct: 601 LEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIAG---IVAYELSEMTAFRRAD 657 Query: 64 AQVI 67 A+ + Sbjct: 658 AEAV 661
>PF05272#Virulence-associated E family protein Length = 892 Score = 33.5 bits (76), Expect = 0.002 Identities = 15/53 (28%), Positives = 22/53 (41%) Query: 26 SDQLLVLVGAQGSGKTTLLTALATDVDDSNTALVICPMHADNAEIRRKILVQL 78 D +VL G G GK+TL+ L S+T I +I + +L Sbjct: 595 FDYSVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIAGIVAYEL 647
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 34.4 bits (79), Expect = 4e-04 Identities = 20/90 (22%), Positives = 31/90 (34%), Gaps = 17/90 (18%) Query: 164 ISYEKAFEQIRAGDVIYCDPP-------YAPLSTTASFTTYVGAGFSLDDQALLARYSRH 216 I E ++ V+ +P Y T T+ D Q R Sbjct: 245 IQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYT----DAQVQ---TVRK 297 Query: 217 MALEQRIPVVISNHDIPLTRELYRGAHLAK 246 +A E+ +P++ IPL R LY A + Sbjct: 298 IAEEEGVPIL---QRIPLARALYWDALVDH 324
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 27.7 bits (61), Expect = 0.008 Identities = 9/50 (18%), Positives = 20/50 (40%), Gaps = 4/50 (8%) Query: 15 AKVLKELGHPTRLALF----RILVKGGYEGVAVGQLQEELQVPGSTLSHH 60 A+ K+ TR + R+ + G ++G++ + V + H Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWH 51
>MECHCHANNEL#Bacterial mechano-sensitive ion channel signature. Length = 136 Score = 169 bits (430), Expect = 1e-57 Identities = 89/136 (65%), Positives = 111/136 (81%), Gaps = 1/136 (0%) Query: 1 MSLIQEFKAFASRGNVIDMAVGIIIGAAFGKIVSSFVADIIMPPIGIILGGVNFSDLSVV 60 MS+I+EF+ FA RGNV+D+AVG+IIGAAFGKIVSS VADIIMPP+G+++GG++F +V Sbjct: 1 MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60 Query: 61 LLAAQGDAPAVVIAYGKFIQTVIDFTIIAFAIFMGLKAINSLKRKQEEAPPASPAPTKDQ 120 L AQGD PAVV+ YG FIQ V DF I+AFAIFM +K IN L RK+EE P A+PAPTK++ Sbjct: 61 LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEE-PAAAPAPTKEE 119 Query: 121 ELLSEIRDLLKAQQEK 136 LL+EIRDLLK Q + Sbjct: 120 VLLTEIRDLLKEQNNR 135
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 123 bits (310), Expect = 2e-32 Identities = 86/400 (21%), Positives = 168/400 (42%), Gaps = 17/400 (4%) Query: 42 AFMAILDIQITNASMKEIQGSLGATLEEGSWISTAYLVAEMIAIPLSGWLSTGLSVRRYL 101 +F ++L+ + N S+ +I +W++TA+++ I + G LS L ++R L Sbjct: 23 SFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLL 82 Query: 102 LWTTAAFIFASILCSISWNLES-MIAFRALQGFFGGALIPLAFRLILEFLPENKRAVGMA 160 L+ F S++ + + S +I R +QG A L ++ ++P+ R Sbjct: 83 LFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFG 142 Query: 161 LFGVTATFAPSIGPTLGGWLTEHFSWHYLFYINVPPGLLVMAMLAYGLEKRPVVWDKLKN 220 L G +GP +GG + + W YL +P ++ L K+ V + Sbjct: 143 LIGSIVAMGEGVGPAIGGMIAHYIHWSYLL--LIPMITIITVPFLMKLLKKEVRIKG--H 198 Query: 221 ADLAGIVTMALGMGCLEVVLEEGNRKDWFGSDLIRNLAIIAAVNLVLFVWIQLNRKDPLV 280 D+ GI+ M++G+ + F + + I++ ++ ++FV DP V Sbjct: 199 FDIKGIILMSVGIVFFML----------FTTSYSISFLIVSVLSFLIFVKHIRKVTDPFV 248 Query: 281 NLRLLGKRDFVLSTVAYFLLGMALFGAIYLIPLYLSQVHDYTPLEIGEVIMWMGFPQLLV 340 + L F++ + ++ + G + ++P + VH + EIG VI++ G +++ Sbjct: 249 DPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVII 308 Query: 341 L-PLVPRLMQRFDGRYLAAFGFFMFALSYYMNSQMTADYAGQQMIASQVVRALGQPFILV 399 + L+ R Y+ G ++S+ S + M V G F Sbjct: 309 FGYIGGILVDRRGPLYVLNIGVTFLSVSFLTAS-FLLETTSWFMTIIIVFVLGGLSFTKT 367 Query: 400 PIGMLATAHLKPHENPSASTVLNVMRNLGGAFGIALVATL 439 I + ++ LK E + ++LN L GIA+V L Sbjct: 368 VISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGL 407
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.8 bits (85), Expect = 1e-05 Identities = 19/73 (26%), Positives = 32/73 (43%), Gaps = 7/73 (9%) Query: 81 ASIGRVVISPAGRGQGLATPLMQQAIEAALTAWPEAGIQIGAQEYLNA----FYQKLGFH 136 A I + ++ R +G+ T L+ +AIE A G+ + Q+ +N FY K F Sbjct: 90 ALIEDIAVAKDYRKKGVGTALLHKAIEWAKEN-HFCGLMLETQD-INISACHFYAKHHFI 147 Query: 137 ACS-EVYLEDGIP 148 + + L P Sbjct: 148 IGAVDTMLYSNFP 160
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 44.1 bits (104), Expect = 4e-08 Identities = 17/73 (23%), Positives = 29/73 (39%), Gaps = 6/73 (8%) Query: 11 TILLVDDDDVDYIAVQRAMKRLRLLNPLVRARDGLEALTILTNTDAIKGAYLILLDLNMP 70 TIL+ DDD + +A+ R + + + A L++ D+ MP Sbjct: 5 TILVADDDAAIRTVLNQALSRAGY--DVRITSNAATLWRWI----AAGDGDLVVTDVVMP 58 Query: 71 RMNGFEFLEHIRS 83 N F+ L I+ Sbjct: 59 DENAFDLLPRIKK 71
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 62.9 bits (153), Expect = 1e-12 Identities = 26/102 (25%), Positives = 48/102 (47%), Gaps = 3/102 (2%) Query: 3 LLLIDDDEVDRTAIIRALRQSKLAFNVVEANCAFDGLNLALQRHFDGILLDYLLPDANGL 62 +L+ DDD RT + +AL S+ ++V + A D ++ D ++PD N Sbjct: 6 ILVADDDAAIRTVLNQAL--SRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 63 EVLIKLNSMTQEQTVVVMLSRYEDEKLAQRCIELGAQDFLLK 104 ++L ++ + V+++S A + E GA D+L K Sbjct: 64 DLLPRIKKA-RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPK 104
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 110 bits (276), Expect = 2e-35 Identities = 43/88 (48%), Positives = 64/88 (72%) Query: 2 NKTELIAKIAENADITKAQATRALKSFEAAITESMKNGDKISIVGFGSFETTTRAARTGR 61 NK +LIAK+AE ++TK + A+ + +A++ + G+K+ ++GFG+FE RAAR GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 62 NPQTGKEIQIAEATVPKFKAGKTLRDSV 89 NPQTG+EI+I + VP FKAGK L+D+V Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAV 90
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 62.5 bits (152), Expect = 2e-13 Identities = 24/107 (22%), Positives = 44/107 (41%), Gaps = 3/107 (2%) Query: 146 RVLVVDDSRMARNVIKRTIGNLGIKLITEAEDGAQAIELMRHNMFDLIITDYNMPSVDGL 205 +LV DD R V+ + + G + + A + DL++TD MP + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 206 ALTQFIRSESQQSHVPILMVSSEANDAHLSNVSQAGVNALCDKPFEP 252 L I+ + +P+L++S++ S+ G KPF+ Sbjct: 64 DLLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDL 108 Score = 47.9 bits (114), Expect = 2e-08 Identities = 30/155 (19%), Positives = 58/155 (37%), Gaps = 6/155 (3%) Query: 10 SMLIVEPSETQRRIIIKCLQQEGIVSIEHAANIAEAKGLIARHKPDLIASAMHFEDGTAT 69 ++L+ + R ++ + L + G + +N A IA DL+ + + D A Sbjct: 5 TILVADDDAAIRTVLNQALSRAGY-DVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 70 EFLSYLRSKSEYKDIQFMLVSSECRREQLESFRQSGVVAILPKPFNAEHLGKALNATIDL 129 + L ++ D+ +++S++ + G LPKPF+ L + + Sbjct: 64 DLLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 130 LSHDELDLSHFDVHDVRVLVVDDSRM--ARNVIKR 162 L D D LV + M V+ R Sbjct: 122 PKRRPSKLED-DSQDGMPLVGRSAAMQEIYRVLAR 155
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 28.9 bits (65), Expect = 0.012 Identities = 9/32 (28%), Positives = 17/32 (53%) Query: 74 ANKAELAETIAQETGKPQWETATEVAAMIGKI 105 ANK +L +A+ T + ++A V A+ + Sbjct: 2 ANKQDLIAKVAEATELTKKDSAAAVDAVFSAV 33
>PF06580#Sensor histidine kinase Length = 349 Score = 29.1 bits (65), Expect = 0.039 Identities = 19/123 (15%), Positives = 45/123 (36%), Gaps = 25/123 (20%) Query: 326 NFELDPSIQRLPIHREDGMELLGNLLDNAFKWA------DSQVTVKLWKAQNKLYLSIDD 379 +++P+I + + L+ L++N K ++ +K K + L +++ Sbjct: 243 ENQINPAIMDVQVPPM----LVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVEN 298 Query: 380 DGPGVADDELDKLTQRGTRLDESVMGHGLGLSIVKE-IAEQYGIELKFTHSRRLSGLCIE 438 G + + G GL V+E + YG E + S + + Sbjct: 299 TGSLALKNTKE--------------STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAM 344 Query: 439 LVL 441 +++ Sbjct: 345 VLI 347
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 84.1 bits (208), Expect = 5e-21 Identities = 34/118 (28%), Positives = 59/118 (50%), Gaps = 1/118 (0%) Query: 2 KLLLVEDNPMLVSELEKQLKQAGYVTDITDKALEADYLVKETQYDCVILDIGLPDGNGLE 61 +L+ +D+ + + L + L +AGY IT A + D V+ D+ +PD N + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 LLEGWRNQGISTPVIMLTARSQWHEKVEGFNAGADDYLGKPFHAQELLARI-QALIHR 118 LL + PV++++A++ + ++ GA DYL KPF EL+ I +AL Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122
>MPTASEINHBTR#Metalloprotease inhibitor signature. Length = 122 Score = 27.7 bits (61), Expect = 0.017 Identities = 8/37 (21%), Positives = 13/37 (35%), Gaps = 5/37 (13%) Query: 88 CCLKGDMVSPALALLASQ-----AQNLAQQLQLHQSE 119 C + VS +AS +A QL + + Sbjct: 10 CVWQVLFVSAGAQAMASSFVVPSTAQMAGQLGIEATG 46
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 43.3 bits (102), Expect = 3e-08 Identities = 17/25 (68%), Positives = 22/25 (88%) Query: 8 GFTLVELMVVIAIIGILASLALPSY 32 GFTL+E+MVVI IIG+LASL +P+ Sbjct: 9 GFTLLEIMVVIVIIGVLASLVVPNL 33
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 57.2 bits (138), Expect = 1e-13 Identities = 28/105 (26%), Positives = 49/105 (46%), Gaps = 10/105 (9%) Query: 5 QKGFTLIELMIAVAIIGILAAIAIPSFNEYLKQGRRFDAQQYLVTSAQALERHYSRNGLY 64 Q+GFTL+E+M+ + IIG+LA++ +P+ ++ + A +V AL+ + N Y Sbjct: 7 QRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDNHHY 66 Query: 65 PASQ----SLANSPYYSFSYTPTADKFGFSLKAVPTNRQSDPCGT 105 P + SL +P +K +P +DP G Sbjct: 67 PTTNQGLESLVEAPTL--PPLAANYNKEGYIKRLP----ADPWGN 105
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 77.9 bits (192), Expect = 1e-16 Identities = 31/133 (23%), Positives = 57/133 (42%), Gaps = 1/133 (0%) Query: 1279 LDGMSILVADDNATARDIMRTTLESMGFNVDTVRSGDEAIMRCSQQEYAVALIDWKMPNL 1338 + G +ILVADD+A R ++ L G++V + + + + + D MP+ Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 1339 DGIETAKQIKQQTKNAPRILMVSAHANQDFLTQIEQLGLAGYISKPISASRLLDGIMNAL 1398 + + +IK+ + P ++M SA + + G Y+ KP + L+ I AL Sbjct: 61 NAFDLLPRIKKARPDLPVLVM-SAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119 Query: 1399 GRSGILPVRRHQD 1411 P + D Sbjct: 120 AEPKRRPSKLEDD 132 Score = 68.3 bits (167), Expect = 1e-13 Identities = 25/103 (24%), Positives = 42/103 (40%), Gaps = 2/103 (1%) Query: 1425 RILLVEDNEMNLEVATEFLEQVGIILSIATNGQIALDKLAQQSFDLVLMDCQMPVMDGYQ 1484 IL+ +D+ V + L + G + I +N +A DLV+ D MP + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 1485 ATKAIRQRPELAQLPVIAMTANAMAGDKEMCLRAGMNDHIAKP 1527 I++ LPV+ M+A G D++ KP Sbjct: 65 LLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKP 105
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 87.6 bits (217), Expect = 3e-21 Identities = 37/159 (23%), Positives = 63/159 (39%), Gaps = 6/159 (3%) Query: 1 MDKATILVVDDTPENIDILVGILG-EDYKVKVAIDGPRALALVTKTLPDLILLDVMMPGM 59 M ATILV DD +L L Y V++ + + DL++ DV+MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 60 NGYEVCKLLKQEPLTCHIPVIFVTALSEVADEAQGFALGAVDYITKPVSAPVVKARVKTH 119 N +++ +K+ +PV+ ++A + + GA DY+ KP + + Sbjct: 61 NAFDLLPRIKKARP--DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 120 LALYDQKRLLEQQVKERTQEL--EETRF-EIIRRLGRAA 155 LA ++ + + L EI R L R Sbjct: 119 LAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLM 157
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 203 bits (519), Expect = 3e-61 Identities = 100/293 (34%), Positives = 132/293 (45%), Gaps = 42/293 (14%) Query: 128 WGMNNTGQSGGTADADIDAPEAWEITTGSSDVVIGVIDTGVDYNHPDLQANMWVNAGEIA 187 N G I AP W T G V + V+DTG D +HPDL+A + Sbjct: 16 EQQVNEIPRGVEM---IQAPAVWNQTRGR-GVKVAVLDTGCDADHPDLKARI-------- 63 Query: 188 GNGIDDDANGVIDDIHGYSAVNNNGN----PMDGNGHGTHVSGTIGAKGNNGVGVVGVNW 243 I G + +++ D NGHGTHV+GTI A N GVVGV Sbjct: 64 --------------IGGRNFTDDDEGDPEIFKDYNGHGTHVAGTIAA-TENENGVVGVAP 108 Query: 244 DVKIAGCQFLDTDGYGSTAGAIACIDYFTNLKVNHGVDIKATNNSWGGGGFSQALKDAIE 303 + + + L+ G G I I Y + VDI + S GG L +A++ Sbjct: 109 EADLLIIKVLNKQGSGQYDWIIQGIYYA----IEQKVDI--ISMSLGGPEDVPELHEAVK 162 Query: 304 AGGEAGILFVAAAGNDAVDND--ASPHYPSSYNSDVVFSIASTTRNDRMSDFSQWGLTSV 361 + IL + AAGN+ +D YP YN V S+ + + S+FS V Sbjct: 163 KAVASQILVMCAAGNEGDGDDRTDELGYPGCYNE--VISVGAINFDRHASEFSNSN-NEV 219 Query: 362 DMGAPGSAILSTVRGGGYATYSGTSMATPHVTGAAALVWALNPDLTPVEMKEL 414 D+ APG ILSTV GG YAT+SGTSMATPHV GA AL+ L ++ E Sbjct: 220 DLVAPGEDILSTVPGGKYATFSGTSMATPHVAGALALIKQLANASFERDLTEP 272
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 27.1 bits (60), Expect = 0.049 Identities = 6/26 (23%), Positives = 13/26 (50%) Query: 34 HQGHITLVKEAAKKCDHVVASIFVNP 59 GH+ +++ + D V ++ NP Sbjct: 13 TFGHLDIIERGCRLFDQVYVAVLRNP 38
>PF04605#Virulence-associated protein D (VapD) Length = 125 Score = 29.1 bits (65), Expect = 0.010 Identities = 8/52 (15%), Positives = 17/52 (32%), Gaps = 2/52 (3%) Query: 65 AADDILRTLEAYGFEWDDTVLYQSART--DAYQAKLDQLLAQDDAYFCQCSR 114 I + + GFE Y S + ++ L + + +C + Sbjct: 27 PYSLIKKFMLENGFEHRQYSGYTSKEPINERRVIRIVNKLTKKFTWLGECVK 78
>INVEPROTEIN#Salmonella/Shigella invasion protein E (InvE) signature. Length = 372 Score = 27.0 bits (59), Expect = 0.031 Identities = 22/81 (27%), Positives = 33/81 (40%), Gaps = 13/81 (16%) Query: 24 GEEYMNAKQLGHFKTILEAWRNQLREEVDRTLSHMQDEAANFPDPVDRAAQEEEFSLELR 83 E AKQ+ ++ L + + + S FPDP D E LR Sbjct: 88 DEALPKAKQILKLISVH---GGALEDFLRQARSL-------FPDPSDLVLVLREL---LR 134 Query: 84 ARDRERKLIKKIEKTLQKIEE 104 +D E + KK+E L+ +EE Sbjct: 135 RKDLEEIVRKKLESLLKHVEE 155
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 137 bits (346), Expect = 2e-44 Identities = 50/142 (35%), Positives = 74/142 (52%) Query: 12 EEIAAGLNQLLADSYSLYLKTHSFHWNVTGPMFTSLHLLFEQQYTELALAVDLIAERVRA 71 + LN L++ + LY K H FHW V GP F +LH FE+ Y A VD IAER+ A Sbjct: 11 TLVENSLNTQLSNWFLLYSKLHRFHWYVKGPHFFTLHEKFEELYDHAAETVDTIAERLLA 70 Query: 72 LGARALGSYSAYAKLTEIHEDQGVTKAETMIRELLSDQEVVIRNARALYPLVSQANDEAT 131 +G + + + Y + I + T A M++ L++D + + ++ + L + D AT Sbjct: 71 IGGQPVATVKEYTEHASITDGGNETSASEMVQALVNDYKQISSESKFVIGLAEENQDNAT 130 Query: 132 ADLLTQRIQIHEKNAWMLRSLL 153 ADL I+ EK WML S L Sbjct: 131 ADLFVGLIEEVEKQVWMLSSYL 152
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 47.6 bits (113), Expect = 2e-09 Identities = 18/87 (20%), Positives = 32/87 (36%), Gaps = 10/87 (11%) Query: 56 LTHTSGQLFGFAIIQQIVDEV----------TLLDICLVPAEQGQGFGRLLLDAIIEDAK 105 + F + + + + + DI + + +G G LL IE AK Sbjct: 60 VEEEGKAAFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAK 119 Query: 106 NAGAVVVMLEVRESNLAARALYQNRGF 132 +MLE ++ N++A Y F Sbjct: 120 ENHFCGLMLETQDINISACHFYAKHHF 146
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 29.0 bits (65), Expect = 0.029 Identities = 20/109 (18%), Positives = 39/109 (35%), Gaps = 3/109 (2%) Query: 37 AAKAYVLMDYYSGQIIAEENAYESLNPASLTKMMTSYVIGQEIKAGNVSPDDDVTISKNA 96 + MD SG+ + A E S K++ + + AG+ + + + Sbjct: 38 GRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQD 97 Query: 97 WSKNFSDSSKMFIEVGKTVKVSDLNRGIIIQSGNDACVAMAEHIAGTEG 145 ++S S+ + + V +L I S N A + + G G Sbjct: 98 L-VDYSPVSEKH--LADGMTVGELCAAAITMSDNSAANLLLATVGGPAG 143
>adhesinb#Adhesin B signature. Length = 310 Score = 29.4 bits (66), Expect = 0.013 Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 8/68 (11%) Query: 10 LLMLSCCFVLAACSSSNSASASASNKNKNMEPNKGRYSL-KN---DKMPLN---PPNVD- 61 +L+L LAACSS S++ + S+K + N + KN DK+ L+ P D Sbjct: 8 VLLLLAFVGLAACSSQKSSTETGSSKLNVVATNSIIADITKNIAGDKINLHSIVPVGQDP 67 Query: 62 HVPNATPK 69 H P+ Sbjct: 68 HEYEPLPE 75
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 77.2 bits (190), Expect = 2e-17 Identities = 31/172 (18%), Positives = 82/172 (47%), Gaps = 4/172 (2%) Query: 436 VTIVEERTIGPTLGAENIENGFAALGLGMGITLLFMALWYR-RLGWVANVALISNMVILF 494 + I ++GP + E + +L + + ++ + + + A VAL+ ++++ Sbjct: 135 LKITSFESVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGAVVALVHDVLLTV 194 Query: 495 GLLALIPGAVLTLPGIAGLVLTVGMAVDTNVLIFERIKDKLKEGRSFALA--IDTGFDSA 552 GL A++ L +A L+ G +++ V++F+R+++ L + ++ L ++ + Sbjct: 195 GLFAVL-QLKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRDVMNLSVNET 253 Query: 553 FSTIFDANFTTMITAVVLYSIGNGPIQGFALTLGLGLLTSMFTGIFASRALI 604 S TT++ V + G I+GF + G+ T ++ ++ ++ ++ Sbjct: 254 LSRTVMTGMTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAKNIV 305
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 237 bits (607), Expect = 2e-79 Identities = 91/299 (30%), Positives = 153/299 (51%), Gaps = 20/299 (6%) Query: 2 KNINLTKWRYISSAISIFLMLASLTIVCVKGFNWGLDFTGGVVTEVQLDRKITSSELQPL 61 N + +W++ + +I +M+AS+ + V G N+G+DF GG + I + Sbjct: 12 TNFDFFRWQWATFGAAIVMMIASVILPLVIGLNFGIDFKGGTTIRTESTTAIDVGVYRAA 71 Query: 62 LNAAYQQDVSVISASEP--------------------GRWVLRYADTAQSHVDIAQTLAP 101 L DV + +P G + A Sbjct: 72 LEPLELGDVIISEVRDPSFREDQHVAMIRIQMQEDGQGAEGQGAQGQELVNKVETALTAV 131 Query: 102 LGEVQVLNTSVVGPQVGKELAEQGGLALLVAMLAILGYLSYRFEWRLASGALFALVHDVM 161 +++ + VGP+V EL +LL A + I+ Y+ RFEW+ A GA+ ALVHDV+ Sbjct: 132 DPALKITSFESVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGAVVALVHDVL 191 Query: 162 FVLAFFSLTQMEFNLTVLAAVLAILGYSLNDSIIIADRIRELLIAKPKLAIQEINNQAIV 221 + F++ Q++F+LT +AA+L I GYS+ND++++ DR+RE LI + ++++ N ++ Sbjct: 192 LTVGLFAVLQLKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRDVMNLSVN 251 Query: 222 ATFSRTMVTSGTTLMTVGALWIMGGGPLEGFSIAMFIGILTGTFSSISVGTSLPEFLGL 280 T SRT++T TTL+ + + I GG + GF AM G+ TGT+SS+ V ++ F+GL Sbjct: 252 ETLSRTVMTGMTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAKNIVLFIGL 310
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 34.0 bits (78), Expect = 0.002 Identities = 23/82 (28%), Positives = 32/82 (39%), Gaps = 18/82 (21%) Query: 193 VLMVGPPGTGKTLLAKAIAGESK---VPFFT-----ISGSDFVEMFVGV------GASRV 238 +++ G GTGK L+A+A+ K PF I G GA Sbjct: 163 LMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTR 222 Query: 239 RD-MFEQAKKSAPCIIFIDEID 259 FEQA+ +F+DEI Sbjct: 223 STGRFEQAEGGT---LFLDEIG 241
>adhesinb#Adhesin B signature. Length = 310 Score = 31.4 bits (71), Expect = 0.003 Identities = 18/95 (18%), Positives = 34/95 (35%), Gaps = 16/95 (16%) Query: 142 REARRTFEVIAEELDIVIQKNGTMAFDNAIIAY----EPLWAVGTGKSATPEQAQEVHAF 197 +EA+ F I E +++ G F AY +W + T + TP+Q + + Sbjct: 186 KEAKEKFNNIPGEKKMIVTSEG--CFKYFSKAYNVPSAYIWEINTEEEGTPDQIKTLVEK 243 Query: 198 IRKRLSEVSPFIGENIRILYGGSVTPSNAADLFAQ 232 +RK + L+ S ++ Sbjct: 244 LRKT----------KVPSLFVESSVDDRPMKTVSK 268
>SECGEXPORT#Protein-export SecG membrane protein signature. Length = 110 Score = 118 bits (298), Expect = 2e-38 Identities = 63/111 (56%), Positives = 82/111 (73%), Gaps = 1/111 (0%) Query: 1 MYEVLVVVYLLVALGLIGLILIQQGKGADMGASFGAGASGTLFGSSGSGNFLTRTTAILA 60 MYE L+VV+L+VA+GL+GLI++QQGKGADMGASFGAGAS TLFGSSGSGNF+TR TA+LA Sbjct: 1 MYEALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFGSSGSGNFMTRMTALLA 60 Query: 61 IAFFTLSLLIGNLSANHAKNEDAWKNLGSDTEQVTQPVEQGTEKSETKIPD 111 FF +SL++GN+++N W+NL S + Q K + IP+ Sbjct: 61 TLFFIISLVLGNINSNKTNKGSEWENL-SAPAKTEQTQPAAPAKPTSDIPN 110
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 71.0 bits (174), Expect = 1e-14 Identities = 51/202 (25%), Positives = 77/202 (38%), Gaps = 30/202 (14%) Query: 392 IMGHVDHGKTSLLDYIRRAKVAAGEAG------------------GITQHIGAYHVETEN 433 ++ HVD GKT+L + + A E G GIT G + EN Sbjct: 8 VLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWEN 67 Query: 434 GMITFLDTPGHAAFTAMRARGAKATDIVVLVVAADDGVMPQTIEAIQHAKAGNVPLIVAV 493 + +DTPGH F A R D +L+++A DGV QT + +P I + Sbjct: 68 TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFI 127 Query: 494 NKMDKPEADIDRV----KSELSQHGVMS-------EDWGGDNMFAFVSAKTGAGVDDLLE 542 NK+D+ D+ V K +LS V+ + + G DDLLE Sbjct: 128 NKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGNDDLLE 187 Query: 543 GILLQAEVLELKAVRDGMAAGV 564 + + LE + + Sbjct: 188 K-YMSGKSLEALELEQEESIRF 208
>SECA#SecA protein signature. Length = 901 Score = 31.0 bits (70), Expect = 0.006 Identities = 10/41 (24%), Positives = 25/41 (60%), Gaps = 1/41 (2%) Query: 81 ESLEEKVAQIEDEENRKLAKKEKDALKD-EIITSLLPRAFS 120 ++E ++ ++ DEE + + + L+ E++ +L+P AF+ Sbjct: 29 NAMEPEMEKLSDEELKGKTAEFRARLEKGEVLENLIPEAFA 69
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 81.8 bits (202), Expect = 8e-20 Identities = 81/346 (23%), Positives = 131/346 (37%), Gaps = 47/346 (13%) Query: 6 KTLLASALASATLASAYAAEPLTVYGKLNV---TAQSNDENGDAT------TTIQSNASR 56 K+L+A LA+ +A A +T+YG + T++S NG T I S+ Sbjct: 3 KSLIALTLAALPVA---AMADVTLYGTIKAGVETSRSVAHNGAQAASVETGTGIVDLGSK 59 Query: 57 FGVKGDFELSSSLSAFYTVEYQVDTGAASSDNFTARNQFVGLKGDFGSFSVGRNDTLLKI 116 G KG +L + L A + VE + S R F+GLKG FG VGR +++LK Sbjct: 60 IGFKGQEDLGNGLKAIWQVEQKASIAGTDSGWGN-RQSFIGLKGGFGKLRVGRLNSVLK- 117 Query: 117 SQGDVDQFNDLSGDLG--KLFKGEVRAAQTATYLTPSFGDFVFGVTYVAEGNDVKSQFAQ 174 GD++ ++ S LG K+ + E R Y +P F V Y A ++ Sbjct: 118 DTGDINPWDSKSDYLGVNKIAEPEARLIS-VRYDSPEFAGLSGSVQY-ALNDNAGRH-NS 174 Query: 175 DGFSVAAMY--GDAKLKKTAVYAALAYDSDVSG---YEVLRASLQAKLAGIKLGGMYQQQ 229 + + Y G ++ Y + Y++ R + QQQ Sbjct: 175 ESYHAGFNYKNGGFFVQYGGAYKRHHQVQENVNIEKYQIHRLVSGYDNDALYASVAVQQQ 234 Query: 230 EQT-YKLDKTTSLPVEVTAESA---------TGYLLSAAYDINAVTLKAQFQDMEDLGDS 279 + + + + + EV A A Y +A + + D Sbjct: 235 DAKLVEENYSHNSQTEVAATLAYRFGNVTPRVSYAHGFKGSFDAT-------NYNNDYDQ 287 Query: 280 WSVGADYNLGKPTKVFAFYTNRSLEANTDDDKYI----AIGLEHKF 321 VGA+Y+ K T L+ + K++ +GL HKF Sbjct: 288 VVVGAEYDFSKRTSALVSA--GWLQEGKGESKFVSTAGGVGLRHKF 331
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 91.4 bits (227), Expect = 1e-23 Identities = 34/130 (26%), Positives = 64/130 (49%), Gaps = 4/130 (3%) Query: 3 ARILIVEDELAIREMLTFVMEQHGFTTSAAEDFDSAIALLKEPYPDLILLDWMFPGGSGI 62 A IL+ +D+ AIR +L + + G+ + + + DL++ D + P + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 63 QLAKRLKQDEFTRQIPIIMLTARGEEEDKVKGLEVGADDYITKPFSPKELVARIKAVL-- 120 L R+K+ +P+++++A+ +K E GA DY+ KPF EL+ I L Sbjct: 64 DLLPRIKKAR--PDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 121 RRSAPTRLEE 130 + P++LE+ Sbjct: 122 PKRRPSKLED 131
>PF06580#Sensor histidine kinase Length = 349 Score = 32.9 bits (75), Expect = 0.002 Identities = 31/189 (16%), Positives = 62/189 (32%), Gaps = 34/189 (17%) Query: 246 ALMQQQTQRMQSMVEQLLVLSRIEDAADIDLENTVNMSQLMDVLK---EEAKALAKDKYE 302 AL+ + + + M+ L L R + V+++ + V+ + A +D+ + Sbjct: 184 ALILEDPTKAREMLTSLSELMRY--SLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQ 241 Query: 303 LSFHCEPGLDSHGNELQLRSACSNLISNAIRY----TEPGGKISVQWRSVATGGLFSVAD 358 P + + L+ N I++ GGKI ++ V + Sbjct: 242 FENQINPAIM---DVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVEN 298 Query: 359 TGEGIAPQHISRLTERFYRVDSARSRQTGGSGLGLAIVKHALSHHHSE---LNISSELGK 415 TG +G GL V+ L + + +S + GK Sbjct: 299 TGSLALKN------------------TKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGK 340 Query: 416 GSTFSFVIP 424 + +IP Sbjct: 341 VNAM-VLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.019 Identities = 13/28 (46%), Positives = 16/28 (57%) Query: 42 TLAIVGEAGSGKSTLARILVGAEPRSGG 69 TL I GE+G+GK +AR L R G Sbjct: 162 TLMITGESGTGKELVARALHDYGKRRNG 189
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.6 bits (69), Expect = 0.009 Identities = 9/16 (56%), Positives = 14/16 (87%) Query: 38 LVGESGSGRSLLARAI 53 + GESG+G+ L+ARA+ Sbjct: 165 ITGESGTGKELVARAL 180
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 99.1 bits (247), Expect = 2e-24 Identities = 54/284 (19%), Positives = 89/284 (31%), Gaps = 84/284 (29%) Query: 194 LIGSPKIWDGSATGTKAMGEGVIVGIIDSGINSDHASFADIGGDGYDHSNPLGQGIYIGD 253 +I +P +W+ + G GV V ++D+G ++DH Sbjct: 28 MIQAPAVWNQTR------GRGVKVAVLDTGCDADHPDLKA-------------------- 61 Query: 254 CKTDFTSMCNDKLIGVRSYSEITNNYDDAKVFGDKPPAKNGEDYGGHGSHVASTAAGNIL 313 ++IG R++++ GD K DY GHG+HVA T A Sbjct: 62 -----------RIIGGRNFTDDDE--------GDPEIFK---DYNGHGTHVAGTIAAT-- 97 Query: 314 LNVPYVQGEAGKLEAEGIPTDIKFAQISGVAPHANIIAYQICNPGNAGDTYSGCPTAPIL 373 GVAP A+++ ++ N Y I+ Sbjct: 98 --------------ENENGV-------VGVAPEADLLIIKVLN-KQGSGQYDW-----II 130 Query: 374 KAIDDSIKDGVDVLNFSISGGGNPWNSATEQGFLAARNAGIFTAVAAGNTRPATATSAAI 433 + I +I+ VD+++ S+ G + + A + I AAGN + Sbjct: 131 QGIYYAIEQKVDIISMSLGGPED--VPELHEAVKKAVASQILVMCAAGNEGDGDDRTD-- 186 Query: 434 TQTPYSTPKNAPWYTSVANSTHDRDIVSAVEFNGKNYSFTAGSG 477 P SV DR N + G Sbjct: 187 ---ELGYPGCYNEVISVGAINFDRHASEFSNSNNEVDLVAPGED 227 Score = 64.5 bits (157), Expect = 8e-13 Identities = 28/112 (25%), Positives = 42/112 (37%), Gaps = 27/112 (24%) Query: 622 VAAPGTDIYAAYADQQFGHDKTGTDPADFTLMSGTSMASPHVAGAGALLKSL-----HKD 676 + APG DI + + SGTSMA+PHVAGA AL+K L +D Sbjct: 221 LVAPGEDILSTVPGG------------KYATFSGTSMATPHVAGALALIKQLANASFERD 268 Query: 677 WTPDQIRSALMLTATTAQAMKKADAKTIADPFDVGAGRIRVDLAAKTGLVMD 728 T ++ + L+ P G G + + + + D Sbjct: 269 LTEPELYAQLIKRTI----------PLGNSPKMEGNGLLYLTAVEELSRIFD 310
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 61.0 bits (148), Expect = 3e-12 Identities = 75/392 (19%), Positives = 148/392 (37%), Gaps = 37/392 (9%) Query: 14 RDTRLMWALCVASVVVYINLYLMQGMLPLLAEHFSVPGSQATLILSVTSFSLAFSLLIYA 73 R +++ LC+ S +N ++ LP +A F+ P + + + + + +Y Sbjct: 11 RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYG 70 Query: 74 VVSDRIGRHTPIVVSLWLLALSNLL-LIWVEDFNALVYVRFLQGILLAAVPAIAMAYFKE 132 +SD++G ++ + + +++ + F+ L+ RF+QG AA PA+ M Sbjct: 71 KLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVAR 130 Query: 133 QLSPSTMLKAAGIYIMANSIGGIAGRLLGGVMSQFLSWQESMWLLFLVTLAGVALTNYLL 192 + KA G+ ++G G +GG+++ ++ W + L+ ++T+ V LL Sbjct: 131 YIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS-YLLLIPMITIITVPFLMKLL 189 Query: 193 PSGADAK---------VMSGG------QTSSPSRSKRARLLQDFYGFSHHL---TDP--Q 232 K +MS G T+S S S + F F H+ TDP Sbjct: 190 KKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVD 249 Query: 233 MRL--------AYAIGGITFMMMVNQFSFIQLHLMAAPYEWSRFQA--TLIFLCYSSGTV 282 L GGI F + S + +M ++ S + +IF S + Sbjct: 250 PGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPY-MMKDVHQLSTAEIGSVIIFPGTMSVII 308 Query: 283 ASYFTAKWLAKFGQHKLYQWSWCLMLLGSL---LTLFDTTLTICMGFLMTACGFFLTHSC 339 Y + + G + + + L L T+ + + + G T + Sbjct: 309 FGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTV 368 Query: 340 CNSFVAMRAS-RDRAKATSLYLCCYYLGAALG 370 ++ V+ ++ SL +L G Sbjct: 369 ISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTG 400
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 500 bits (1288), Expect = e-162 Identities = 214/1049 (20%), Positives = 446/1049 (42%), Gaps = 75/1049 (7%) Query: 3 LTRLAIKLPVTTSMFFFAILLFGLASSRLLPLEMFPGIDIPQIVVQVPYKGSTPAEVERD 62 + I+ P+ + +++ G + LP+ +P I P + V Y G+ V+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 63 ITKVLEESLATMGGIDELESESSQEG-AEIEINMKWGENVATKSLEAREKIDAVRHLLPR 121 +T+V+E+++ + + + S S G I + + G + ++ + K+ LLP+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 122 DVERVFIRQFSTADMPVLTIRISSDRELSGAFDLLD---KQLKRPLERVEGVSKVSLYGV 178 +V++ I ++ ++ SD + D+ D +K L R+ GV V L+G Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG- 179 Query: 179 EQKQIEVRINANRLAASGFSATELQARLARENFVLSAGTL------RESNLVYQVSPKGE 232 Q + + ++A+ L + ++ +L +N ++AG L L + + Sbjct: 180 AQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 233 FRNLEDIKALVLVPGLT-----LGDVADVQFSLPERSEGRHLDQHYAVGLDVFKESGANL 287 F+N E+ + L L DVA V+ + ++ A GL + +GAN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 288 VEVSDRVLKVIEQAKQDQQFQGIRLFIMEDQASGVKSSLTDLLLSGLVGALLSFIILYLF 347 ++ + + + + + QG+++ D V+ S+ +++ + +L F+++YLF Sbjct: 300 LDTAKAIKAKLAELQPFFP-QGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLF 358 Query: 348 LRNFKMTMIVVSSVPISIGMTLAAMYLLGYSLNILSMMGLLLAVGMLIDNAVVVTESVLQ 407 L+N + T+I +VP+ + T A + GYS+N L+M G++LA+G+L+D+A+VV E+V + Sbjct: 359 LQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 418 Query: 408 EKQGNSVNSNPQDNENAVMTGVDKVSLAVLAGTLTTAIVFLPNIFGVKVQLTIFLEHVAI 467 + P++ A + ++ A++ + + VF+P + +I Sbjct: 419 VMMED--KLPPKE---ATEKSMSQIQGALVGIAMVLSAVFIP-MAFFGGSTGAIYRQFSI 472 Query: 468 AICISLAASLLVAKTLIPLMLTKFHFDIEPDNTTGK-------------LQNFYNRSLNW 514 I ++A S+LVA L P + + ++ K N Y S+ Sbjct: 473 TIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGK 532 Query: 515 VLIRPWRSGLISIAILASTALPISMVKQDQEDSQSKERIYINYQVEGRHNLNVTEAMVNQ 574 +L R LI I+A + + + + Q+ T+ +++Q Sbjct: 533 ILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQ 592 Query: 575 MEDYLYKNKEQ--FHIDTVYSY----YAPDDASSVILLKKDLPMPLDELKQKIRSGFP-- 626 + DY KN++ + TV + A + + + LK P +E S Sbjct: 593 VTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLK-----PWEERNGDENSAEAVI 647 Query: 627 ---KYSIAKPQFGWGDDNSGVRVTLTGRST--------------SELIHLSEQVLPLL-K 668 K + K + G+ + + G +T L Q+L + + Sbjct: 648 HRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQ 707 Query: 669 NIKGLVDVRSEVNGAQQEVVIRINRQMAARLDLKLNEVASSISMALRGTPLRSFRHDPSG 728 + LV VR + + ++++ A L + L+++ +IS AL GT + F D Sbjct: 708 HPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFI-DRGR 766 Query: 729 ELRIEMAYEKEWQKSLDKLKQLPVVRIDQRLYTLDNLASIEIQPRFDTIKHYNRQTSLSI 788 ++ + + +++ + + +L V + + + ++ YN S+ I Sbjct: 767 VKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEI 826 Query: 789 GANLDN-LTTEEAQTKIKQVMENVSFPDGYNYSLRGGFERQEEDQSIMVINMLLAIAMIY 847 ++ +A ++ + + P G Y G ++ + + ++ +++ Sbjct: 827 QGEAAPGTSSGDAMALMENLASKL--PAGIGYDWTGMSYQERLSGNQAPALVAISFVVVF 884 Query: 848 IVMAALFESLLLPTAIITSILFSITGVFWALLLTGTPMSVMAMIGILILMGVVVNNGIVL 907 + +AAL+ES +P +++ + I GV A L V M+G+L +G+ N I++ Sbjct: 885 LCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILI 944 Query: 908 VDQINQ-MTPELDKLSDTIREVCITRLRPVLMTVGTTVLGLVPLAMDDTQIGGGGPPYYP 966 V+ M E + + RLRP+LMT +LG++PLA+ G G Sbjct: 945 VEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAIS---NGAGSGAQNA 1001 Query: 967 MAIAIIGGLSFSTLTSLYLVPLCYQLLYR 995 + I ++GG+ +TL +++ VP+ + ++ R Sbjct: 1002 VGIGVMGGMVSATLLAIFFVPVFFVVIRR 1030
>SECA#SecA protein signature. Length = 901 Score = 31.0 bits (70), Expect = 0.019 Identities = 15/45 (33%), Positives = 23/45 (51%), Gaps = 4/45 (8%) Query: 29 QIISNAIASKGNAVIEAGTGVGKTFAYLIPAM---LSGKQVIVST 70 Q++ + ++ + E TG GKT +PA L+GK V V T Sbjct: 87 QLLGGMVLNERC-IAEMRTGEGKTLTATLPAYLNALTGKGVHVVT 130
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 60.5 bits (147), Expect = 1e-13 Identities = 49/145 (33%), Positives = 71/145 (48%), Gaps = 14/145 (9%) Query: 1 MFTWLKGLISKDLLIELSEAKITINAFGDKASIEYEPLLALVTEHNKMMIK---AIGHEA 57 M +G+ S DL I+L A I G + + EP + + + K A+GH+A Sbjct: 1 MLKKFRGMFSNDLSIDLGTANTLIYVKG-QGIVLNEPSVVAIRQDRAGSPKSVAAVGHDA 59 Query: 58 STLDG---EGIRIVNPFSHPRMFVASFALAEKLLQYGISQLHS-SGFRAAPRVILHQLEK 113 + G I + P +A F + EK+LQ+ I Q+HS S R +PRV++ Sbjct: 60 KQMLGRTPGNIAAIRPMKDG--VIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLV----C 113 Query: 114 TEGGLTDIEDRVLRELAMGAGAREV 138 G T +E R +RE A GAGAREV Sbjct: 114 VPVGATQVERRAIRESAQGAGAREV 138
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 114 bits (286), Expect = 7e-37 Identities = 33/89 (37%), Positives = 54/89 (60%) Query: 4 TKAEMAEHLFETLGINKRVAKEMVESFFEEIRGALESGEQVKLSGFGNFDLRDKNQRPGR 63 K ++ + E + K+ + V++ F + L GE+V+L GFGNF++R++ R GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 64 NPKTGEDIPISARRVVTFRPGQKLKTRVE 92 NP+TGE+I I A +V F+ G+ LK V+ Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAVK 91
>BORPETOXINA#Bordetella pertussis toxin A subunit signature. Length = 269 Score = 29.4 bits (65), Expect = 0.019 Identities = 13/27 (48%), Positives = 15/27 (55%) Query: 22 WVTWLAIGLLVIFGIMPAWLRDPIAKV 48 W+TWLAI + PAW DP A V Sbjct: 15 WLTWLAILAVTAPVTSPAWADDPPATV 41
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 67.5 bits (165), Expect = 2e-14 Identities = 28/107 (26%), Positives = 47/107 (43%), Gaps = 5/107 (4%) Query: 2 AIKVLVVDDSTLIRSLLGKMIESDPELSLVGMAADAYMAKDMVNQFRPDVITLDIEMPKV 61 +LV DD IR++L + + + ++A + D++ D+ MP Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRI--TSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 62 DGLTFLDRLMKARPTA-VVMISALTEEGADATFNALALGAVDFIPKP 107 + L R+ KARP V+++SA A GA D++PKP Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNT--FMTAIKASEKGAYDYLPKP 105
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 76.0 bits (187), Expect = 8e-17 Identities = 34/201 (16%), Positives = 69/201 (34%), Gaps = 19/201 (9%) Query: 255 KVLLVDDQQSMVDYFSSLLRSHGLMVRGMTKPEQVIPTLEQFEPDLFIFDLYMPGVNGLE 314 +L+ DD ++ + L G VR + + + + DL + D+ MP N + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 315 LARMIRQLDKYTSSPILVLSSDDTMQNKVSIIQAGSDDLISKQTAP--SLFVTQVISRAQ 372 L I++ P+LV+S+ +T + + G+ D + K + + Sbjct: 65 LLPRIKKARPDL--PVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 373 RGHDIRSSASRDSLTGLLNHTQILVAARHCINLAKRANSSVCIAMLDLDHFKQVNDTYGH 432 + + L+ + + + + + ++ I G Sbjct: 123 KRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMIT--------------GE 168 Query: 433 SGGDKVLLAFAHLLQQSLRAA 453 SG K L+A A L R Sbjct: 169 SGTGKELVARA-LHDYGKRRN 188 Score = 46.7 bits (111), Expect = 2e-07 Identities = 32/135 (23%), Positives = 61/135 (45%), Gaps = 4/135 (2%) Query: 132 IAIIEDDNNVGAMITKQLHEFGFNVQHFLNFTDFIKVQYASPFDLILLDLILPDYTEDAL 191 I + +DD + ++ + L G++V+ N + A DL++ D+++PD E+A Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPD--ENAF 63 Query: 192 -FEAACEFEKNNTRVFVLSSRSDFDMRLLAIRANVSEYFVKPAETTLLVRKIHQWLKMSD 250 + + + V V+S+++ F + A +Y KP + T L+ I + L Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 251 KPPLKVLLVDDQQSM 265 + P L D Q M Sbjct: 124 RRP-SKLEDDSQDGM 137
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 29.3 bits (66), Expect = 0.039 Identities = 16/36 (44%), Positives = 24/36 (66%) Query: 137 NIVIDIGGGSTEVVLGQKNTPTHLSSLRCGCVSFNE 172 ++V+DIGGG+TEV + N + SS+R G F+E Sbjct: 161 SMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDE 196
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 42.4 bits (100), Expect = 3e-06 Identities = 27/83 (32%), Positives = 43/83 (51%), Gaps = 15/83 (18%) Query: 191 AAKRAGFVDVAFLFEPLAAGMDYEAGLKADQTV--LVVDVGGGTTDCSVVKMGPSHKASF 248 +A+ AG +V + EP+AA + AGL + +VVD+GGGTT+ +V+ + Sbjct: 129 SAQGAGAREVFLIEEPMAAAIG--AGLPVSEATGSMVVDIGGGTTEVAVISLN------- 179 Query: 249 DRSRDCLGHSGQRIGGNDLDIAL 271 + S RIGG+ D A+ Sbjct: 180 ----GVVYSSSVRIGGDRFDEAI 198
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 62.9 bits (153), Expect = 9e-14 Identities = 27/130 (20%), Positives = 53/130 (40%), Gaps = 2/130 (1%) Query: 3 RIAIVEDEAAIRENYKDVLQQHGYSVQTYADRPSAMLAFNTRLPDLAIIDIGLGNEIDGG 62 I + +D+AAIR L + GY V+ ++ + DL + D+ + +E Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE--NA 62 Query: 63 FMLCQSLRAMSNTLPIIFLTARDSDFDTVCGLRLGADDYLSKEVSFPHLTARLAALFRRS 122 F L ++ LP++ ++A+++ + GA DYL K L + Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 123 ELAASQTPQE 132 + S+ + Sbjct: 123 KRRPSKLEDD 132
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 61.1 bits (148), Expect = 6e-13 Identities = 27/125 (21%), Positives = 52/125 (41%), Gaps = 11/125 (8%) Query: 147 ELALGMNVQFRTGSSELEADFLPQLDNVATVMKRSSESN--LELKGYAERRGDWRDNQSL 204 L +V F + L+ + LD + + + + + + GY +R G NQ L Sbjct: 214 HFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGL 273 Query: 205 SEHRLLEVRDYLIQQGVAPARMTTQALG-----AAMSLNEQLDSESDVS----DRRVTLT 255 SE R V DYLI +G+ +++ + +G + + + + DRRV + Sbjct: 274 SERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIE 333 Query: 256 IPPTQ 260 + + Sbjct: 334 VKGIK 338
>PF06580#Sensor histidine kinase Length = 349 Score = 228 bits (584), Expect = 3e-72 Identities = 62/198 (31%), Positives = 114/198 (57%), Gaps = 3/198 (1%) Query: 357 EQQQNLLTQAELKLLQAQVNPHFLFNALNTISAIIKRDPDMSKQLLQQLSQFLRINLKRT 416 + ++ +A+L L+AQ+NPHF+FNALN I A+I DP ++++L LS+ +R +L+ + Sbjct: 152 WKMASMAQEAQLMALKAQINPHFMFNALNNIRALILEDPTKAREMLTSLSELMRYSLRYS 211 Query: 417 TG-LVTLGDELDHIASYLTIEKARFINKLQVNIAIPESLYHCKVPAFTLQPIIENAVKHG 475 V+L DEL + SYL + +F ++LQ I ++ +VP +Q ++EN +KHG Sbjct: 212 NARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHG 271 Query: 476 TSHMIDQGQIKVTGRLDEHVLALEVIDNAGLYQPST-DSEGLGMNLVHKRIQNLFGEQYG 534 + + G+I + G D + LEV + L +T +S G G+ V +R+Q L+G + Sbjct: 272 IAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQMLYGTEAQ 331 Query: 535 LQVECEPDEYTKVIIRLP 552 +++ + + ++ +P Sbjct: 332 IKLSEKQGKVN-AMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 67.9 bits (166), Expect = 2e-15 Identities = 33/115 (28%), Positives = 53/115 (46%), Gaps = 9/115 (7%) Query: 5 LIVDDELFAREELADSLSQEADIEIIGQCSNAIEALQTITKEKPQLVFLDIQMPRISGME 64 L+ DD+ R L +LS+ + SNA + I LV D+ MP + + Sbjct: 7 LVADDDAAIRTVLNQALSRAG--YDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 65 LIAML---DPDTLPKIVFVTAFDEF--AVKAFDNHAFDYLLKPIDADRLSKTLKR 114 L+ + PD ++ ++A + F A+KA + A+DYL KP D L + R Sbjct: 65 LLPRIKKARPDL--PVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 25.9 bits (56), Expect = 0.049 Identities = 14/47 (29%), Positives = 19/47 (40%), Gaps = 2/47 (4%) Query: 69 NKLPLPAAKSIQAPAKEPSKKSAP--KPNSKPTQTKVVTPTPAVEGQ 113 N PLP + PA P+ P +PN +P P +GQ Sbjct: 324 NAQPLPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTDGQ 370
>OMADHESIN#Yersinia outer membrane adhesin signature. Length = 455 Score = 26.4 bits (57), Expect = 0.031 Identities = 14/38 (36%), Positives = 21/38 (55%) Query: 11 NDKLDKFRRKLAAAEQRGDVVIVAQFKREIEAVTKQIN 48 ++ L++ LAA + D V VAQ K+EIE + N Sbjct: 189 HESLNRQLTHLAAGTKDTDAVNVAQLKKEIEKTQENTN 226
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.9 bits (158), Expect = 1e-13 Identities = 28/135 (20%), Positives = 56/135 (41%), Gaps = 7/135 (5%) Query: 2 AIKVLVVDDSSFFRRRVSEIVNQDPELEVIATASNGAEAVKMTADLNPQVITMDIEMPVM 61 +LV DD + R +++ +++ + SN A + A + ++ D+ MP Sbjct: 3 GATILVADDDAAIRTVLNQALSR--AGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 62 DGITAVREIMAKCP-TPILMFSSLTHDGAKATLDALDAGALDFLPKRF--EDIATNKDEA 118 + + I P P+L+ S+ + + A + GA D+LPK F ++ A Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSA--QNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 119 ILLLQQRVKALGRRR 133 + ++R L Sbjct: 119 LAEPKRRPSKLEDDS 133
>PF06580#Sensor histidine kinase Length = 349 Score = 43.3 bits (102), Expect = 2e-06 Identities = 19/105 (18%), Positives = 37/105 (35%), Gaps = 23/105 (21%) Query: 450 TLNKEIDLVLV---------GEETDLDKNLVEALADPLVH------LVRNSVDHGIEMPN 494 +L E+ +V + + + A+ D V LV N + HGI Sbjct: 217 SLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGIA--- 273 Query: 495 DREASGKPRTGVITLSASQEGDHILLKIEDDGAGMDPEKLKQIAI 539 P+ G I L +++ + L++E+ G+ + Sbjct: 274 -----QLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGT 313
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.9 bits (223), Expect = 3e-24 Identities = 33/105 (31%), Positives = 51/105 (48%), Gaps = 3/105 (2%) Query: 6 KILIVDDFSTMRRIIKNLLRDLGFNNTQEADDGSTALPMLQKGDFDFVVTDWNMPGMQGI 65 IL+ DD + +R ++ L G++ + +T + GD D VVTD MP Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 66 DLLKAIRADDSLKHLPVLMVTAEAKREQIIAAAQAGVNGYVVKPF 110 DLL I+ LPVL+++A+ I A++ G Y+ KPF Sbjct: 64 DLLPRIKKAR--PDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPF 106
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.8 bits (69), Expect = 0.012 Identities = 9/25 (36%), Positives = 12/25 (48%) Query: 238 VKQGGVVALVGPTGVGKTTSLAKLA 262 K V L G G+GK+T + L Sbjct: 593 CKFDYSVVLEGTGGIGKSTLINTLV 617
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.3 bits (71), Expect = 0.013 Identities = 26/158 (16%), Positives = 52/158 (32%), Gaps = 19/158 (12%) Query: 485 VVDAATVVATHISQILTNNAAKLLGYEEAQQLMDMLAKHSPKLVDGFIPDV-MPLGNVVK 543 V D + T ++Q L+ + A L +A LV + DV MP N Sbjct: 8 VADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLV---VTDVVMPDENAFD 64 Query: 544 VMQNLLNEGVSVR--------DLRTIVQTL----LEYGTKSNDTEVLTAAVRIAL---KR 588 ++ + + T ++ +Y K D L + AL KR Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 589 MIVQEISGPELEIPVITLAPELEQMLHQSMQATGGDGP 626 + + +P++ + ++++ + D Sbjct: 125 RPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLT 162
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 335 bits (861), Expect = e-116 Identities = 96/347 (27%), Positives = 178/347 (51%), Gaps = 2/347 (0%) Query: 6 SGERSEEPTGRRLDQAREKGQVARSKELGTATVLLSAATGLYMLGPGIAKALSNVFERVF 65 SGE++E+PT +++ AR+KGQVA+SKE+ + ++++ + L L + S + + Sbjct: 2 SGEKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLM--LI 59 Query: 66 TMDRAAIFDTNQMFNVWGVVGSEIGWPLLKIMLLIVVVAFIGNVSLGGMNFSTQAMMPKA 125 +++ + + + V V E + ++ + ++A +V G S +A+ P Sbjct: 60 PAEQSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDI 119 Query: 126 SKMSPIAGFKRMFGVQALVELTKGIAKFSVVALASYLLLSHYFNDILLLSADHLPGNVYH 185 K++PI G KR+F +++LVE K I K ++++ ++++ +L L + Sbjct: 120 KKINPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPL 179 Query: 186 ALDLLVWMFILLCSSVLVIVVIDVPFQIWNHNKQLKMTKQEVKDEYKDTEGKPEVKGRVR 245 +L + ++ +VI + D F+ + + K+LKM+K E+K EYK+ EG PE+K + R Sbjct: 180 LGQILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKRR 239 Query: 246 QMQRELAQRRMMAEVPNADVIVVNPEHYAVAIKYDVKRSAAPFVIAKGVDEVAFKIREVA 305 Q +E+ R M V + V+V NP H A+ I Y + P V K D +R++A Sbjct: 240 QFHQEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIA 299 Query: 306 RAHNIAIVTAPPLARAIYHTTKLDQQVPEGLFTAVAQVLAYVFQLRQ 352 + I+ PLARA+Y +D +P A A+VL ++ + Sbjct: 300 EEEGVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQNI 346
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 119 bits (301), Expect = 8e-35 Identities = 92/243 (37%), Positives = 141/243 (58%), Gaps = 1/243 (0%) Query: 15 YMWPLFRVASMLMVMVVFGAATTPTRVRLLLAIAITLAIAPVLPPVKDAQLFSLSAVFIT 74 Y WPL RV +++ + + P RV+L LA+ IT AIAP LP +FS A+++ Sbjct: 16 YFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPANDVP-VFSFFALWLA 74 Query: 75 AQQIIIGVAMGFVTQMVMQTFVLTGQIIGMQTSLGFASMVDPSSGQQTPVIGNFFLLLAT 134 QQI+IG+A+GF Q G+IIG+Q L FA+ VDP+S PV+ +LA Sbjct: 75 VQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHLNMPVLARIMDMLAL 134 Query: 135 LIFLAVDGHLLMIRMLVASFDTLPISNVGLTLTSYRSLAEWGSYMFGAALTMSLSAIIAL 194 L+FL +GHL +I +LV +F TLPI L ++ +L + GS +F L ++L I L Sbjct: 135 LLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLIFLNGLMLALPLITLL 194 Query: 195 LLVNLSFGVMTRAAPQLNIFSIGFPITMIGGLLILWLTLTPVMAHFDEVWASAQLLLCDI 254 L +NL+ G++ R APQL+IF IGFP+T+ G+ ++ + + + +++ LL DI Sbjct: 195 LTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFCEHLFSEIFNLLADI 254 Query: 255 LGL 257 + Sbjct: 255 ISE 257
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 46.7 bits (111), Expect = 1e-10 Identities = 21/73 (28%), Positives = 39/73 (53%) Query: 4 EALIDIFREALAVIVMMVSAIVLPGLGIGLIVAVFQAATSINEQTLSFLPRLIVTLLALM 63 + L+ +AL +++++ + IGL+V +FQ T + EQTL F +L+ L L Sbjct: 2 DDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLF 61 Query: 64 LMGHWLVQTLMDF 76 L+ W + L+ + Sbjct: 62 LLSGWYGEVLLSY 74
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 276 bits (708), Expect = 2e-96 Identities = 120/240 (50%), Positives = 175/240 (72%) Query: 8 FIGLSTLLFVTSAGAADGVLPAVTVKTAADGSTEYSVTMQILLLMTSLSFIPAMVIMLTS 67 + ++ +L A LP +T + G +S+ +Q L+ +TSL+FIPA+++M+TS Sbjct: 4 LLSVAPVLLWLITPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLMMTS 63 Query: 68 FTRIIVVLSILRQAIGLQQTPSNQVLIGMSLFMTFFIMAPVFDKIYDQGVKPYIDEQLTL 127 FTRII+V +LR A+G P NQVL+G++LF+TFFIM+PV DKIY +P+ +E++++ Sbjct: 64 FTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEKISM 123 Query: 128 QQAFDKGKEPLRAFMLGQVRTTDLKTFIDISGYQNINSPEEAPMSVLVPAFITSELKTAF 187 Q+A +KG +PLR FML Q R DL F ++ + PE PM +L+PA++TSELKTAF Sbjct: 124 QEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELKTAF 183 Query: 188 QIGFMLFVPFLVLDLVVASILMAMGMMMLSPMIVSLPFKIMLFVLVDGWGLVMGTLANSF 247 QIGF +F+PFL++DLV+AS+LMA+GMMM+ P ++LPFK+MLFVLVDGW L++G+LA SF Sbjct: 184 QIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLAQSF 243
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 112 bits (281), Expect = 4e-35 Identities = 54/122 (44%), Positives = 81/122 (66%) Query: 2 STDDDWAAAMAEQALEEANAVGLDELVDDSQPISKAEAAKLDTILDIPVTISMEVGRSFI 61 + DD WA A+ EQ + +D I+DIPV +++E+GR+ + Sbjct: 14 ALDDLWADALNEQKATTTKSAADAVFQQLGGGDVSGAMQDIDLIMDIPVKLTVELGRTRM 73 Query: 62 SIRNLLQLNQGSVVELDRVAGEPLDVMVNGTLIAHGEVVVVNDKFGIRLTDVISQTERIK 121 +I+ LL+L QGSVV LD +AGEPLD+++NG LIA GEVVVV DK+G+R+TD+I+ +ER++ Sbjct: 74 TIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGVRITDIITPSERMR 133 Query: 122 KL 123 +L Sbjct: 134 RL 135
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 245 bits (628), Expect = 1e-81 Identities = 88/327 (26%), Positives = 164/327 (50%), Gaps = 12/327 (3%) Query: 1 MSDLLSQDEIDALLHGVDDVEEDNELDAVGQEARS----YDFSSQDRIVRGRMPTLEIVN 56 M+++LSQDEID LL + + E DA YDF D+ + +M TL +++ Sbjct: 1 MTEVLSQDEIDQLLTAISSGDASIE-DARPISDTRKITLYDFRRPDKFSKEQMRTLSLMH 59 Query: 57 ERFARHLRISMFNMMRRAAEVSINGVQMLKFGEYVHTLFVPTSLNMVRFHPLKGTALITM 116 E FAR S+ +R V + V L + E++ ++ P++L ++ PLKG A++ + Sbjct: 60 ETFARLTTTSLSAQLRSMVHVHVASVDQLTYEEFIRSIPTPSTLAVITMDPLKGNAVLEV 119 Query: 117 EARLVFILVDNFFGGDGRFHAKIEGREFTPTERRIVQLLLKIIFEDYKDAWAPVMDVEFD 176 + + F ++D FGG G+ R+ T E +++ ++ I + +++W V+D+ Sbjct: 120 DPSITFSIIDRLFGGTGQAAKVQ--RDLTDIENSVMEGVIVRILANVRESWTQVIDLRPR 177 Query: 177 YLDSEVNPAMANIVSPTEVVVINSFHIEVDGGGGDFHITMPYSMIEPIRELLDAG--VQS 234 E NP A IV P+E+VV+ + +V G + +PY IEPI L + S Sbjct: 178 LGQIETNPQFAQIVPPSEMVVLVTLETKVGEEEGMMNFCIPYITIEPIISKLSSQFWFSS 237 Query: 235 DKQDTDMRWSQALHDEIMDVKVGFDATVVEHELTLKDVMNFKAGDIIPIE---LPEYIMM 291 ++ + ++ L D++ V + A V L+++D++ + GDII + + + ++ Sbjct: 238 VRRSSTTQYMGVLRDKLSTVDMDVVAEVGSLRLSVRDILGLRVGDIIRLHDTHVGDPFVL 297 Query: 292 RIEDLPTYRCKMGRSRDNLALKIYEKI 318 I + + C+ G +A +I E+I Sbjct: 298 SIGNRKKFLCQPGVVGKKIAAQILERI 324
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 52.5 bits (125), Expect = 2e-09 Identities = 36/132 (27%), Positives = 62/132 (46%), Gaps = 5/132 (3%) Query: 401 MKQQLVTMVSQGIQQAEIRLDPPELGHMLVKIQVHGDQTQVQFHVAQSQTRDLVEQAIPR 460 + Q + QG Q AE+RL P +LG + + ++V +Q Q+Q R +E A+P Sbjct: 244 LSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMVSPHQHVRAALEAALPV 303 Query: 461 LRELLQEQGMQLADSHVSQGDQGQRREGGFGEAGGSSGGNVDDFSAEELD-----LGLNQ 515 LR L E G+QL S++S +++ + N + + E+ D + L Sbjct: 304 LRTQLAESGIQLGQSNISGESFSGQQQAASQQQQSQRTANHEPLAGEDDDTLPVPVSLQG 363 Query: 516 ATSLNSAIDYYA 527 + NS +D +A Sbjct: 364 RVTGNSGVDIFA 375
>FLGFLIJ#Flagellar FliJ protein signature. Length = 147 Score = 43.7 bits (102), Expect = 3e-08 Identities = 37/145 (25%), Positives = 73/145 (50%) Query: 1 MANTDPLLLVLKLALDAEEQAALLLKSAQLECQKRQNQLDALNNYRLDYMKQMQSQQGQA 60 MA L + LA E AA LL + CQ+ + QL L +Y+ +Y + S Sbjct: 1 MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAG 60 Query: 61 ISASHYHQFHRFIRQIDEAIAQQQRVVADGEKQKNYRQHYWLEKQKKRKAVELLLDNKEK 120 I+++ + + +FI+ +++AI Q ++ + ++ + + W EK+++ +A + L + + Sbjct: 61 ITSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQST 120 Query: 121 KRQAIELKKEQKMTDEFASQQFYRR 145 E + +QK DEFA + R+ Sbjct: 121 AALLAENRLDQKKMDEFAQRAAMRK 145
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 89.9 bits (222), Expect = 2e-23 Identities = 61/202 (30%), Positives = 106/202 (52%), Gaps = 6/202 (2%) Query: 54 APKAVAVETVAPPTMAEIEDIRAQAEEEGFNEGKTQGHIEGLEQGRLEGLEQGHKEGFTQ 113 AP + P IE+ E++ + + Q H +G + G EG +QGHK+G+ + Sbjct: 16 APPQAEFVPIVEPEETIIEEAEPSLEQQ-LAQLQMQAHEQGYQAGIAEGRQQGHKQGYQE 74 Query: 114 GHEQGLETGLAEAKA----LLSRFEGLLCQFEKPLQLLDGDIEHTLMSLTMALAKSVIGH 169 G QGLE GLAEAK+ + +R + L+ +F+ L LD I LM + + A+ VIG Sbjct: 75 GLAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRLMQMALEAARQVIGQ 134 Query: 170 ELKTHPEQILSALRLGVESLPIKEQTVNLRMHPDDVTLVETLYSSTQLTRNQWQLEADPS 229 ++ ++ ++ P+ LR+HPDD+ V+ + +T L+ + W+L DP+ Sbjct: 135 TPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGAT-LSLHGWRLRGDPT 193 Query: 230 LTAGDCIISSQRSLVDLTLSSR 251 L G C +S+ +D ++++R Sbjct: 194 LHPGGCKVSADEGDLDASVATR 215
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 292 bits (748), Expect = 1e-99 Identities = 110/348 (31%), Positives = 194/348 (55%), Gaps = 5/348 (1%) Query: 1 MAENKSKDAAETPSFNVKDLSGIEKTAILLLSLSEADAASILKHLEPKQVQKVGMAMAAM 60 M E K K+ + V L+G +K AILL+S+ ++ + K+L ++++ + +A + Sbjct: 1 MEEKKEKEILD-----VSALTGKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKL 55 Query: 61 EDFGQEKVIGVHKLFLDDIQKYSSIGFNSEEFVRKALTAALGEDKAGNLIEQIIMGSGAK 120 E E V F + + I ++ R+ L +LG KA ++I + ++ Sbjct: 56 ETITSELKDNVLLEFKELMMAQEFIQKGGIDYARELLEKSLGTQKAVDIINNLGSALQSR 115 Query: 121 GLDSLKWMDARQVATIIQNEHPQIQTIVLSYLEPDQAAEIFGQFPENTRLDLMMRIANLE 180 + ++ D + IQ EHPQ ++LSYL+P +A+ I P + ++ RIA ++ Sbjct: 116 PFEFVRRADPANILNFIQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMD 175 Query: 181 EVQPAALQELNDIMEKQFAGQGGAQAAKMGGLKAAANIMNYLDTGVESQLMETMRETDEE 240 P ++E+ ++EK+ A GG+ I+N D E ++E++ E D E Sbjct: 176 RTSPEVVREVERVLEKKLASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPE 235 Query: 241 MAQQIQDLMFVFENLIDVDDRGIQTLLREVQQDVLMKALKGADDQLKDKILGNMSKRAAE 300 +A++I+ MFVFE+++ +DDR IQ +LRE+ L KALK D +++KI NMSKRAA Sbjct: 236 LAEEIKKKMFVFEDIVLLDDRSIQRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRAAS 295 Query: 301 LLRDDLEAMGPIRISEVEIAQKEILSIARRLSDSGEIMLGGGGGDEFL 348 +L++D+E +GP R +VE +Q++I+S+ R+L + GEI++ GG ++ L Sbjct: 296 MLKEDMEFLGPTRRKDVEESQQKIVSLIRKLEEQGEIVISRGGEEDVL 343
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 301 bits (772), Expect = 2e-97 Identities = 160/570 (28%), Positives = 265/570 (46%), Gaps = 56/570 (9%) Query: 27 LGNLGGVDMMRQITMILALAICLALAVFVMIWAQEPEYRPL-GKMETQEMVQVLDVLDKN 85 L L + +I +I+A + +A+ V +++WA+ P+YR L + Q+ ++ L + Sbjct: 13 LEWLNRLRANPRIPLIVAGSAAVAIVVAMVLWAKTPDYRTLFSNLSDQDGGAIVAQLTQM 72 Query: 86 KIKYQIDVD--VVKVPEDKYQEVKMMLSRAGIDSAATSKQDFLTQDSGFGVSQRMEQARL 143 I Y+ ++VP DK E+++ L++ G+ + L Q FG+SQ EQ Sbjct: 73 NIPYRFANGSGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQ-EKFGISQFSEQVNY 131 Query: 144 KHSQEENLARAIEQLQSVSRAKVILALPKENVFARNTAQPSATVVINTRRG-GLGQGEVD 202 + + E LAR IE L V A+V LA+PK ++F R PSA+V + G L +G++ Sbjct: 132 QRALEGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLEPGRALDEGQIS 191 Query: 203 AIVDIVASAVQGLEPSRVTVTDSNGRLLNSGSQDGVSARARRELELVQQKETEYRTKIDS 262 A+V +V+SAV GL P VT+ D +G LL + G +L+ E+ + +I++ Sbjct: 192 AVVHLVSSAVAGLPPGNVTLVDQSGHLLTQSNTSGRDL-NDAQLKFANDVESRIQRRIEA 250 Query: 263 ILSPILGHDNFTSQVDVSMDFTAVEQTAKRFNPDLPSLRSEMTVENNST-----GGSTGG 317 ILSPI+G+ N +QV +DF EQT + ++P+ + ++ + + G GG Sbjct: 251 ILSPIVGNGNVHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQVGAGYPGG 310 Query: 318 IPGALSNQPP---------------MESNIPQEAATAATESVAAGNSHREATRNFELDTT 362 +PGALSNQP N PQ + + + S ++ R T N+E+D T Sbjct: 311 VPGALSNQPAPPNEAPIATPPTNQQNAQNTPQTSTSTNSNSAGPRSTQRNETSNYEVDRT 370 Query: 363 ISHTRQQIGVVRRVSVSVAVDFKPGAAGENGQVARVARTEQELTNIRRLLEGAVGFSAQR 422 I HT+ +G + R+SV+V V++K A G+ + T ++ I L A+GFS +R Sbjct: 371 IRHTKMNVGDIERLSVAVVVNYKTLADGKP-----LPLTADQMKQIEDLTREAMGFSDKR 425 Query: 423 GDVLEVVTVPFMDQLVEDVPAPELWEQPWFWRAVKLGVGALVILV----LILAVVRPMLK 478 GD L VV PF + W+Q F + L++LV L VRP L Sbjct: 426 GDTLNVVNSPF-SAVDNTGGELPFWQQQSFIDQLLAAGRWLLVLVVAWILWRKAVRPQLT 484 Query: 479 RLIYPDRVNMPEDGRLGNELAEIEDQYAADTLGMLNTKEAEYSYADDGSIL---IPNLHK 535 R + E E+ E + D + Sbjct: 485 RRVE----EAKAAQEQAQVRQETEE-------------AVEVRLSKDEQLQQRRANQRLG 527 Query: 536 DDDMIKAIRALVANEPELSTQVVKNWLQDN 565 + M + IR + N+P + V++ W+ ++ Sbjct: 528 AEVMSQRIREMSDNDPRVVALVIRQWMSND 557
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 59.3 bits (143), Expect = 5e-15 Identities = 32/101 (31%), Positives = 55/101 (54%) Query: 12 MQSLKGEVTPSFGISPNNIVQQVNNTSGADFGQLLSQAIGNVSGLQSTSSNLATRLDMGD 71 +Q ++G ++ + + Q+ F L A+ +S Q+ + A + +G+ Sbjct: 3 IQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTLGE 62 Query: 72 TTVSLSDSVIAREKASVAFEATIQVRNKLVEAYKEIMSMPV 112 V+L+D + +KASV+ + IQVRNKLV AY+E+MSM V Sbjct: 63 PGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV 103
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 465 bits (1198), Expect = e-164 Identities = 171/484 (35%), Positives = 249/484 (51%), Gaps = 43/484 (8%) Query: 1 MSEAKLLLVEDDASLREALLDTLMLAQYDCIDVASGEEAILALKQHQFDLVISDVQMPGI 60 M+ A +L+ +DDA++R L L A YD ++ + DLV++DV MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 GGLGLLNYLQQHHPKLPVLLMTAYATIGSAVSAIKLGAVDYLAKPFAPEVLLNQVSRYLP 120 LL +++ P LPVL+M+A T +A+ A + GA DYL KPF L+ + R L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 121 LKQNRDQPVVAD-----------EKSLSLLSLAQRVAASDASVMILGPSGSGKEVLARYI 169 + R + D + + R+ +D ++MI G SG+GKE++AR + Sbjct: 121 EPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARAL 180 Query: 170 HQHSSRAEEAFVAINCAAIPENMLEATLFGYEKGAFTGAYQACPGKFEQAQGGTLLLDEI 229 H + R FVAIN AAIP +++E+ LFG+EKGAFTGA G+FEQA+GGTL LDEI Sbjct: 181 HDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEI 240 Query: 230 SEMDLGLQAKLLRVLQEREVERLGGRKTIKLDVRVLATSNRDLKAVVAAGQFREDLYYRI 289 +M + Q +LLRVLQ+ E +GGR I+ DVR++A +N+DLK + G FREDLYYR+ Sbjct: 241 GDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRL 300 Query: 290 NVFPLTWPALNQRPADILPLARHLLTKHAKALNVVDLPEFDDAACRRLLSHRWPGNVREL 349 NV PL P L R DI L RH + + K V FD A + +H WPGNVREL Sbjct: 301 NVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDV--KRFDQEALELMKAHPWPGNVREL 358 Query: 350 DNVVQRALILRAGALITANDIIIDAQDVPLTSDD-------------------------- 383 +N+V+R L +IT I + + S Sbjct: 359 ENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFAS 418 Query: 384 -AEYMSEPEGLGEELKAQEHVIILETLVQCQGSRKLVAEKLGISARTLRYKMARMRDMGI 442 + + L E+ +IL L +G++ A+ LG++ TLR K +R++G+ Sbjct: 419 FGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKK---IRELGV 475 Query: 443 QLPS 446 + Sbjct: 476 SVYR 479
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 441 bits (1135), Expect = e-154 Identities = 168/479 (35%), Positives = 260/479 (54%), Gaps = 17/479 (3%) Query: 7 RILLVGTPSERLSRLCCIFEFLGEQIDII-TIEKLSTCLQETRFRALVISI---DNMSAD 62 IL+ + + L G + I L + +V + D + D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 63 ALKLVASQYPWQPILLFGHVGELQV------SNVLGHIEEPLNYPQLTELLHFCQVYGQV 116 L + P P+L+ ++ +P + +L ++ + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 117 KRPQVPTSANQTKLFRSLVGRSDGIANVRHLISQVATSDATVLVLGQSGTGKEVVARNIH 176 + ++ + LVGRS + + +++++ +D T+++ G+SGTGKE+VAR +H Sbjct: 125 RPSKLEDDSQD---GMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALH 181 Query: 177 YLSERRDGPFIPVNCGAIPPELLESELFGHEKGSFTGAISSRKGRFELAEGGTLFLDEIG 236 +RR+GPF+ +N AIP +L+ESELFGHEKG+FTGA + GRFE AEGGTLFLDEIG Sbjct: 182 DYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIG 241 Query: 237 DMPLQMQVKLLRVLQERVFERVGGTKTINADVRVVAATHRDLETMISSNEFREDLYYRLN 296 DMP+ Q +LLRVLQ+ + VGG I +DVR+VAAT++DL+ I+ FREDLYYRLN Sbjct: 242 DMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLN 301 Query: 297 VFPIEMPALSERKDDVPLLLQELVSRVYNEGRGKVRFTQRAIESLKEHAWSGNVRELSNL 356 V P+ +P L +R +D+P L++ V + EG RF Q A+E +K H W GNVREL NL Sbjct: 302 VVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELENL 361 Query: 357 VERLTILYPGGLVDVNDLPIKYRHIDVPEYSVELSEEQQERDALASIFTSEEPVEIPETR 416 V RLT LYP ++ + + R ++P+ +E + + +++ EE + Sbjct: 362 VRRLTALYPQDVITREIIENELRS-EIPDSPIEKAAARSGSLSISQAV--EENMRQYFAS 418 Query: 417 FPSELPPEGVNLKDLLAELEIDMIRQALEQQDNVVARAAEMLGIRRTTLVEKMRKYGMT 475 F LPP G+ +LAE+E +I AL +AA++LG+ R TL +K+R+ G++ Sbjct: 419 FGDALPPSGL-YDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>INTIMIN#Intimin signature. Length = 939 Score = 33.5 bits (76), Expect = 0.002 Identities = 50/260 (19%), Positives = 78/260 (30%), Gaps = 27/260 (10%) Query: 3 ISATGMGSGLDISNIVKVLVDAEKAPKEAMFNKTEDSIKAKVSAMGTLKSALSTFQDAVK 62 ++A + SN V + + + D K SA A+ T+ VK Sbjct: 527 VTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAI-TYTATVK 585 Query: 63 KLQTGDALNQRKIS-VSTDAYLSAKAEKTAQAGSYGIKVEQVATNHKIAGTNVADATQPV 121 K A + VS A LSA + T +G + + + K V + Sbjct: 586 KNGVAQANVPVSFNIVSGTAVLSANSANTNGSGKATVTL----KSDKPGQVVV---SAKT 638 Query: 122 GEGSLAFGVNGKSFSVDIAATDSLAEIAKKVNEASDNVGVTAT--------------VIT 167 E + A N F A+ + + K A+ +T T V Sbjct: 639 AEMTSALNANAVIFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKGDKPVSNQEVTF 698 Query: 168 SDAGSRLVFSANKTGEDNQISLTAT-NTSGSG-VTDMFGSGNTSTLQDAKN--AVLYIDG 223 + +L S KT + +T T T G V+ L ID Sbjct: 699 TTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDD 758 Query: 224 QKVTSQSNEVKNAITGVTLN 243 + VK + V L Sbjct: 759 GNIEIVGTGVKGKLPTVWLQ 778
>FLAGELLIN#Flagellin signature. Length = 507 Score = 133 bits (335), Expect = 7e-38 Identities = 93/271 (34%), Positives = 129/271 (47%), Gaps = 10/271 (3%) Query: 2 AITVNTNVTSLKAQKNLNTSASDLATSMERLSSGLRINSAKDDAAGLAISNRLNSQVRGL 61 A +NTN SL Q NLN S S L++++ERLSSGLRINSAKDDAAG AI+NR S ++GL Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 EVGMRNANDAISIAQIAEGAMQEQTNMLQRMRDLTVQSENGANSSADLSALKAEMDQLAN 121 RNAND ISIAQ EGA+ E N LQR+R+L+VQ+ NG NS +DL +++ E+ Q Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 EIDEIGKTTAFGTTKLLAGGFSAGKNFQVGAQDGEDIKVTVKASNKSSLSVGSL------ 175 EID + T F K+L+ QVGA DGE I + ++ + SL + Sbjct: 121 EIDRVSNQTQFNGVKVLSQDNQ--MKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPK 178 Query: 176 --GNTTSAARASSLKKIDAAIKTIDAQRADLGAIQNRLAHNISNSANTQANVADAKSRIV 233 + ++ D + R D+ + + A Sbjct: 179 EATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTT 238 Query: 234 DVDFAKETSQMTKNQVLQQTGSAMLAQANQL 264 D + K + A A + Sbjct: 239 DDAENNTAVDLFKTTKSTAGTAEAKAIAGAI 269 Score = 85.9 bits (212), Expect = 4e-21 Identities = 61/213 (28%), Positives = 98/213 (46%), Gaps = 4/213 (1%) Query: 60 GLEVGMRNANDAISIAQIAEGAMQEQTNMLQRMRDLTVQSENGANSSADLSALKAEMDQL 119 + + +++A I GA LQ +++ NG + D + ++ Sbjct: 298 KVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSD 357 Query: 120 ANEIDEIGKTTAFGTTKLLAGGFSAGKNFQVGAQDGEDIKVTVKASNKSSLSVGSLGNTT 179 + + + +AG + + K ++ S + Sbjct: 358 LEANNAVKGESKITVNGAEYTANAAGDKVTLAGK----TMFIDKTASGVSTLINEDAAAA 413 Query: 180 SAARASSLKKIDAAIKTIDAQRADLGAIQNRLAHNISNSANTQANVADAKSRIVDVDFAK 239 + A+ L ID+A+ +DA R+ LGAIQNR I+N NT N+ A+SRI D D+A Sbjct: 414 KKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYAT 473 Query: 240 ETSQMTKNQVLQQTGSAMLAQANQLPQVALSLL 272 E S M+K Q+LQQ G+++LAQANQ+PQ LSLL Sbjct: 474 EVSNMSKAQILQQAGTSVLAQANQVPQNVLSLL 506
>FLAGELLIN#Flagellin signature. Length = 507 Score = 133 bits (336), Expect = 5e-38 Identities = 95/271 (35%), Positives = 128/271 (47%), Gaps = 10/271 (3%) Query: 2 AITVNTNVTSMKAQKNLNTSNSGLSTSMERLSSGLRINSAKDDAAGLAISNRLNSQVRGL 61 A +NTN S+ Q NLN S S LS+++ERLSSGLRINSAKDDAAG AI+NR S ++GL Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 EVGMRNANDAISIAQIAEGAMQEQTNMLQRMRDLTIQSENGANSTADLVSIKAEMDQLAT 121 RNAND ISIAQ EGA+ E N LQR+R+L++Q+ NG NS +DL SI+ E+ Q Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 EIDSIGNSTAFGNTKLLTGTFSAGKVFQVGHQEGEDIKVTVKASNKTSLSVGALNNATSA 181 EID + N T F K+L+ QVG +GE I + ++ + SL + N Sbjct: 121 EIDRVSNQTQFNGVKVLSQDNQ--MKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPK 178 Query: 182 NRASSLAK--------IDAAIKTIDSQRADLGAVQNRLAHNISNSANTQANVADAKSRIV 233 K D + R D+ + + A Sbjct: 179 EATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTT 238 Query: 234 DVDFAKETSAMTKYQVLQQTGSAMLAQANQL 264 D + K + A A + Sbjct: 239 DDAENNTAVDLFKTTKSTAGTAEAKAIAGAI 269 Score = 87.0 bits (215), Expect = 1e-21 Identities = 52/146 (35%), Positives = 76/146 (52%) Query: 127 GNSTAFGNTKLLTGTFSAGKVFQVGHQEGEDIKVTVKASNKTSLSVGALNNATSANRASS 186 N+ + + G K ++ S + A + A+ Sbjct: 361 NNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINEDAAAAKKSTANP 420 Query: 187 LAKIDAAIKTIDSQRADLGAVQNRLAHNISNSANTQANVADAKSRIVDVDFAKETSAMTK 246 LA ID+A+ +D+ R+ LGA+QNR I+N NT N+ A+SRI D D+A E S M+K Sbjct: 421 LASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYATEVSNMSK 480 Query: 247 YQVLQQTGSAMLAQANQLPQVALSLL 272 Q+LQQ G+++LAQANQ+PQ LSLL Sbjct: 481 AQILQQAGTSVLAQANQVPQNVLSLL 506
>FLAGELLIN#Flagellin signature. Length = 507 Score = 55.4 bits (133), Expect = 2e-10 Identities = 65/362 (17%), Positives = 118/362 (32%), Gaps = 16/362 (4%) Query: 20 QTATSKVLEQLSSGKKVNTSGDDPVAALGIDNLNQRNALVDQFMKNIDYANNRLAVTESK 79 Q++ S +E+LSSG ++N++ DD + + Q +N + + TE Sbjct: 21 QSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQASRNANDGISIAQTTEGA 80 Query: 80 LGSAEDLTGSIREQLMRAVNGTLSDSERQMIADEMKDSLKELLSLANSKDESGNYLFSG- 138 L + +RE ++A NGT SDS+ + I DE++ L+E+ ++N +G + S Sbjct: 81 LNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEEIDRVSNQTQFNGVKVLSQD 140 Query: 139 FSTDKQPFAFDNST---PPKIVYSGDSGVRDSLVQSGVAIGTNIPGDQAFMKAPNGLGDY 195 Q A D T + + G+ V GD D Sbjct: 141 NQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKEATV---GDLKSSFKNVTGYDT 197 Query: 196 SVNYLASQQGDFKVQTAKIADQATYVADTYTFNFSDNGAGGVNLQVLDSANNPVANVTNF 255 + D A V D N ++ V F Sbjct: 198 YAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTT-------DDAENNTAVDLF 250 Query: 256 DATTPVSFNGIEVKIDGKPSAGDSFSMEPQSEVSIFDTISNAIALIEDPNVANSPQGKAQ 315 T + I G G V+ TI + V+ + G+ Sbjct: 251 KTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTF--TIDTKTGNDGNGKVSTTINGEKV 308 Query: 316 LAQILNNIDSGVNQMSSARSVAGNNLKTVERYKDTHTEEKVVNTSALSLLEDLDYASAIT 375 + + N ++ + N +V + T ++ ++ LS LE + + Sbjct: 309 TLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSDLEANNAVKGES 368 Query: 376 EF 377 + Sbjct: 369 KI 370
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 214 bits (547), Expect = 5e-64 Identities = 123/455 (27%), Positives = 194/455 (42%), Gaps = 19/455 (4%) Query: 4 DLLNIARTGVLASQSQLGVTSNNIANANTVGYHRQVATQTTLDSQRLGSSFYGTGTYVSD 63 L+N A +G+ A+Q+ L SNNI++ N GY RQ +S + G G YVS Sbjct: 2 SLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVSG 61 Query: 64 VKRIYNDYAARELRIGQTTLSAAEASYGKLSELDQIFSQIGKVVPQSLTDLFAGLNSLAD 123 V+R Y+ + +LR QT S A Y ++S++D + S + + D F L +L Sbjct: 62 VQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLVS 121 Query: 124 LPADLGIRSSTLNDAKQLANSLNQMQSTLNGQLNQTNDQITGMTKRINEISTELANLNLE 183 D R + + ++ L N L Q Q N I +IN + ++A+LN + Sbjct: 122 NAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLNDQ 181 Query: 184 LMKSPNQDPI-----LLDKQDALVQELSQYAQVNVIPLENGAKSIMLGGSIMLVSGEVA- 237 + + LLD++D LV EL+Q V V + G +I + LV G A Sbjct: 182 ISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTAR 241 Query: 238 -MSMSTATGDPFPNELQLMSSIGSQSVKADPSKLGGQLGALFEYRDQTLVPASLELDQLA 296 ++ ++ DP + + + G LG + +R Q L L QLA Sbjct: 242 QLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQLA 301 Query: 297 LGVADSFNKLQAQGFDLNGQVGANMFKDINDPLMSLGRVGGFTDNTGNATLGVNIDDTSA 356 L A++FN GFD NG G + F + V T N G+ +G + D SA Sbjct: 302 LAFAEAFNTQHKAGFDANGDAGEDFFA------IGKPAVLQNTKNKGDVAIGATVTDASA 355 Query: 357 LTGGSYELSF--TAPSTYELRDTQTGAITPLTLNGTKLEGGAGFSIDIKAGAMASGDRFS 414 + Y++SF L T +TP +G G A D F+ Sbjct: 356 VLATDYKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFT----GTPAVNDSFT 411 Query: 415 IRPTAGAANGIEVVMTDPKGIAAAAPKITADTANS 449 ++P + A ++V++TD IA A+ + D+ N Sbjct: 412 LKPVSDAIVNMDVLITDEAKIAMASEEDAGDSDNR 446 Score = 83.1 bits (205), Expect = 8e-19 Identities = 38/103 (36%), Positives = 54/103 (52%) Query: 535 AEGDNTNAVAMAKLSETKVMNGGKSTLADVFELTKQDIGSKTKAAEVRVGSAEAIYKQAY 594 + DN N A+ L GG + D + DIG+KT + + + Q Sbjct: 441 GDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGNKTATLKTSSATQGNVVTQLS 500 Query: 595 ARVESESGVNLDEEAANLMRFQQAYQASARIMSTAQQIFDSLL 637 + +S SGVNLDEE NL RFQQ Y A+A+++ TA IFD+L+ Sbjct: 501 NQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALI 543
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 154 bits (389), Expect = 5e-46 Identities = 66/160 (41%), Positives = 96/160 (60%), Gaps = 2/160 (1%) Query: 214 RETQKTLKFGSREEFLATLYPHAEKAAKALGTKPEVLLAQSALETGWGQKIVRGHNGAPS 273 R +L S+ FLA L A+ A++ G ++LAQ+ALE+GWGQ+ +R NG PS Sbjct: 139 RNYDDSLPGDSKA-FLAQLSLPAQLASQQSGVPHHLILAQAALESGWGQRQIRRENGEPS 197 Query: 274 HNLFNIKADRRWQGDKANVSTLEFEQGIAVRQKADFRVYNDFDHSFNDFVSFIADGERYQ 333 +NLF +KA W+G ++T E+E G A + KA FRVY+ + + +D+V + RY Sbjct: 198 YNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYLEALSDYVGLLTRNPRYA 257 Query: 334 DAKKVAASPTQFIRALQEAGYATDPKYAEKVIKVMQSISE 373 A AAS Q +ALQ+AGYATDP YA K+ ++Q + Sbjct: 258 -AVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQMKS 296 Score = 88.2 bits (218), Expect = 8e-22 Identities = 39/93 (41%), Positives = 61/93 (65%), Gaps = 3/93 (3%) Query: 12 DLGGLDNLRAQAQKDEKGALKKVAQQFEGVFVQMLMKSMRDANAVFESDSPLNSQYTKFY 71 D L+ L+A+A +D ++ VA+Q EG+FVQM++KSMRDA D +S++T+ Y Sbjct: 14 DAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALP---KDGLFSSEHTRLY 70 Query: 72 EQMRDQQLSVDLSDKGVLGLADMMVQQLSPESS 104 M DQQ++ ++ LGLA+MMV+Q++PE Sbjct: 71 TSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQP 103
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 380 bits (976), Expect = e-133 Identities = 157/362 (43%), Positives = 218/362 (60%), Gaps = 12/362 (3%) Query: 8 AVFMLAFSMPSQAERIKDIANVQGVRNNQLIGYGLVVGLPGTGEK---TNYTEQTFTTML 64 F+ + RIKDIA++Q R+NQLIGYGLVVGL GTG+ + +TEQ+ ML Sbjct: 16 LPFLSTPPAQADTSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFTEQSMRAML 75 Query: 65 KNFGINLPENFRPKIKNVAVVAVHADMPAFIKPGQELDVTVSSLGEAKSLRGGTLLQTFL 124 +N GI + KN+A V V A++P F PG +DVTVSSLG+A SLRGG L+ T L Sbjct: 76 QNLGITTQGG-QSNAKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRGGNLIMTSL 134 Query: 125 KGVDGNVYAIAQGSLVVSGFSADGLDGSKVIQNTPTVGRIPNGAIVERSVATPFSTGDYL 184 G DG +YA+AQG+L+V+GFSA G D + + Q T R+PNGAI+ER + + F L Sbjct: 135 SGADGQIYAVAQGALIVNGFSAQG-DAATLTQGVTTSARVPNGAIIERELPSKFKDSVNL 193 Query: 185 TFNLRRSDFSTAQRMADAINDL----LGPDMARPLDATSIQVSAPRDVSQRVSFLATLEN 240 LR DFSTA R+AD +N G +A P D+ I V PR V+ +A +EN Sbjct: 194 VLQLRNPDFSTAVRVADVVNAFARARYGDPIAEPRDSQEIAVQKPR-VADLTRLMAEIEN 252 Query: 241 IEVEPAEESAKVIVNSRTGTIVVGQNVKLLPAAVTHGGLTVTIAEATQVSQPNALANGQT 300 + VE + AKV++N RTGTIV+G +V++ AV++G LTV + E+ QV QP + GQT Sbjct: 253 LTVET-DTPAKVVINERTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQPAPFSRGQT 311 Query: 301 TVTSNSTINATESDRRMFMFNPGTTLDELVRAVNLVGAAPSDVLAILEALKVAGALHGEL 360 V + I A + ++ + G L LV +N +G ++AIL+ +K AGAL EL Sbjct: 312 AVQPQTDIMAMQEGSKVAIVE-GPDLRTLVAGLNSIGLKADGIIAILQGIKSAGALQAEL 370 Query: 361 II 362 ++ Sbjct: 371 VL 372
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 150 bits (379), Expect = 2e-47 Identities = 76/215 (35%), Positives = 107/215 (49%), Gaps = 9/215 (4%) Query: 11 LLLTACSSTPKKPIADDPFYAPVYPEAPPTKIAATGSIYQDSQAA-----SLYSDIRAHK 65 L LT C+ P P+ A P P A GSI+Q +Q L+ D R Sbjct: 17 LSLTGCAWIPSTPLVQGATSAQPVPGPTP---VANGSIFQSAQPINYGYQPLFEDRRPRN 73 Query: 66 VGDIITIVLKEATQAKKSAGNQIKKGSDMTLDPVYAGGSNLSL-GGIPLDLRYKDSMNTK 124 +GD +TIVL+E A KS+ + L G D+ Sbjct: 74 IGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNARADVEASGGNTFN 133 Query: 125 RESDADQSNSLDGSISANIMQVLNNGNLVVRGEKWISINNGDEFIRVTGIVRSQDIKPDN 184 + A+ SN+ G+++ + QVL NGNL V GEK I+IN G EFIR +G+V + I N Sbjct: 134 GKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRFSGVVNPRTISGSN 193 Query: 185 TIDSTRMANARIQYSGTGTFAEAQKVGWLSQFFMS 219 T+ ST++A+ARI+Y G G EAQ +GWL +FF++ Sbjct: 194 TVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLN 228
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 29.1 bits (65), Expect = 0.038 Identities = 20/91 (21%), Positives = 35/91 (38%), Gaps = 7/91 (7%) Query: 728 TLVKILAYSDEYMPQ---YAHILKLCGKIQESVNVY--LDYLKKYASDTQTWIKLGLFMI 782 T+ + S + + Q A GK +++ V+ L L Y S ++ LG Sbjct: 24 TIAMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRF--FLGLGACRQ 81 Query: 783 ELGQAEGAHTAFSNALNADPSNQVAQHYVAE 813 +GQ + A ++S D + AE Sbjct: 82 AMGQYDLAIHSYSYGAIMDIKEPRFPFHAAE 112
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 69.7 bits (170), Expect = 6e-17 Identities = 30/145 (20%), Positives = 54/145 (37%), Gaps = 5/145 (3%) Query: 11 RSEQKKQQVLVAAIDLFCRQGFPHTSMDEVAKLAGVSKQTVYSHYGSKDELFVAAIE--S 68 +++ +Q +L A+ LF +QG TS+ E+AK AGV++ +Y H+ K +LF E Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSE 67 Query: 69 KCVGHNLNDDLLSDPSQPEATITEFALQFGEMIVSPEAITVFKACVAQSESHP---EVSR 125 +G + P P + + E + E V+ E + + V + Sbjct: 68 SNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQ 127 Query: 126 LFFEAGPKHIVGLMADYLVAVEALG 150 + L Sbjct: 128 QAQRNLCLESYDRIEQTLKHCIEAK 152
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 43.3 bits (102), Expect = 1e-06 Identities = 32/158 (20%), Positives = 53/158 (33%), Gaps = 18/158 (11%) Query: 101 RLLEAERQ--EIQASLAQTQADVDLATSTL---KRNLELKKSGYVSEQL--LDETQTQLA 153 +LE E + E L ++ ++ S + K +L + +E L L +T + Sbjct: 253 AVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIG 312 Query: 154 SLEAAKKRLLASQHANQLKLDKSHLLAPFDGIISQRQ-HNLGEVVAAGSPAFTLVGSMNT 212 L N+ + S + AP + Q + H G VV +V +T Sbjct: 313 LLTLELA-------KNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDT 365 Query: 213 -EAYIGVPVAIANQFSTGQNV--KVSVHNQPFTAKIAG 247 E V + GQN KV + G Sbjct: 366 LEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVG 403 Score = 39.0 bits (91), Expect = 3e-05 Identities = 30/137 (21%), Positives = 52/137 (37%), Gaps = 14/137 (10%) Query: 33 ATTAQLQNVITAPLRLSPSYQSEQVFTGTIRAGNTTGVGFELSGKLSELNVDSGANVHQG 92 + Q++ V TA +L+ S G + + + + E+ V G +V +G Sbjct: 75 SVLGQVEIVATANGKLTHS-------------GRSKEIKPIENSIVKEIIVKEGESVRKG 121 Query: 93 QVLAKLDTRLLEAERQEIQASLAQTQADVDLATSTLKRNLELKKSGYVSEQLLDETQTQL 152 VL KL EA+ + Q+SL Q + + L R++EL K + Q Sbjct: 122 DVLLKLTALGAEADTLKTQSSLLQARLEQ-TRYQILSRSIELNKLPELKLPDEPYFQNVS 180 Query: 153 ASLEAAKKRLLASQHAN 169 L+ Q + Sbjct: 181 EEEVLRLTSLIKEQFST 197
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 381 bits (980), Expect = e-118 Identities = 213/1052 (20%), Positives = 428/1052 (40%), Gaps = 62/1052 (5%) Query: 1 MIKAFVENGRLVSLVIALLLVAGFGAMSSLPRTEDPHITNRFASVITPYPGASAERVEAL 60 M F+ ++ +L++AG A+ LP + P I SV YPGA A+ V+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTEVLENQLRRLEEIKLIQSTS-RPGISVIQLELKDTVTDTDPVWSR--ARDLLADARNS 117 VT+V+E + ++ + + STS G I L + TDP ++ ++ L A Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQS---GTDPDIAQVQVQNKLQLATPL 117 Query: 118 LPDDIQTPTL-DDQVGYAYTAILSLVWNDSSQPRVDMLNRYAKELQSRLRLLAGTDFVKL 176 LP ++Q + ++ +Y + V ++ + D+ + A ++ L L G V+L Sbjct: 118 LPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQL 177 Query: 177 YGAPEEEILVQLDGYKMSQLQLTPGTIANILRSADSKIAAGEINN------NHFRALVEV 230 +GA + + + LD +++ +LTP + N L+ + +IAAG++ A + Sbjct: 178 FGA-QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIA 236 Query: 231 SGELDSQSRIRQVPLKVDSDGQIIRLGDIATISRQPKSPADSIGLVDGEQGVFVAARMLN 290 + +V L+V+SDG ++RL D+A + + I ++G+ + ++ Sbjct: 237 QTRFKNPEEFGKVTLRVNSDGSVVRLKDVARV-ELGGENYNVIARINGKPAAGLGIKLAT 295 Query: 291 NTRVDIWQGQVKQLVDEFNIDLPANIKVEWLLEQNSYTSERLGGLVINLIQGFVIILSVL 350 +K + E P +KV + + + + +V L + +++ V+ Sbjct: 296 GANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVM 355 Query: 351 LLTLG-LRNAVIVAISLPLTALFTLACMKYIGLPIHQMSVTGLVVALGIMVDNAIVIVDA 409 L L +R +I I++P+ L T A + G I+ +++ G+V+A+G++VD+AIV+V+ Sbjct: 356 YLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVEN 415 Query: 410 IAQRRQ-QGMSRLNAVTEALHHLWLPLAGSTITTILAFAPIVLMPGATGEFVGGIAMAVM 468 + + + A +++ + L G + F P+ G+TG ++ ++ Sbjct: 416 VERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIV 475 Query: 469 FALFGSYLISHTLIAGLAGRF-------SLEGKNPI--WYQHGINLPLVSGYFQASLRFA 519 A+ S L++ L L E K W+ + V+ Y S+ Sbjct: 476 SAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFD-HSVNHY-TNSVGKI 533 Query: 520 LNRPRLSAILIGTIPLLGFYASGKMTEQFFPPSDRDMFQIELYLAPHVSLENT---LSQV 576 L ++ I ++ F P D+ +F + L + E T L QV Sbjct: 534 LGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQV 593 Query: 577 --YLMDKQLHQIEGITQVDWV-VGGNTPSFYYNLTQRQQGATNYAQAMIK-----TIDFE 628 Y + + +E + V+ G + A +K D Sbjct: 594 TDYYLKNEKANVESVFTVNGFSFSGQAQN------------AGMAFVSLKPWEERNGDEN 641 Query: 629 RANALIPVLQQRFDK---AFPEAQVLVRKLEQGPPFNAPVELM-IFGPDLETLRTLGDEI 684 A A+I + K F + +E G EL+ G + L +++ Sbjct: 642 SAEAVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQL 701 Query: 685 RHILAATP-DVIHTRATLSAGSPKVLLQVNEDASLISGLSLTNIARQVQMSTTGVIGGSV 743 + A P ++ R + + L+V+++ + G+SL++I + + + G Sbjct: 702 LGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDF 761 Query: 744 LEQTESLPIRVRLGENSREQASRLSEIQLMTPSGTAVPLSALSHNEVQVSRGAIPRRNGQ 803 +++ + V+ R + ++ + + +G VP SA + + + R NG Sbjct: 762 IDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGL 821 Query: 804 RVNTIEAYIVSGVLPAQVLNDVKDKVAAIKLPAGYRIEIGGESAKRNEAIGNLLSNIILV 863 I+ G + +++ A KLPAG + G S + + + + + Sbjct: 822 PSMEIQGEAAPGTSSGDAMALMEN--LASKLPAGIGYDWTGMSYQERLSGNQAPALVAIS 879 Query: 864 VTLLLATVVLSFNSFRLTAIILLSALQSAGLGLLAVFVFGYPFGFPVIIALLGLMGLAIN 923 ++ + + S+ + ++L LLA +F ++ LL +GL+ Sbjct: 880 FVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAK 939 Query: 924 AAIVILAELEELPAAR-MGDKAVIVSTVSSCGRHISSTTITTVGGFIPLII---AGGGFW 979 AI+I+ ++L G + V R I T++ + G +PL I AG G Sbjct: 940 NAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQ 999 Query: 980 PPFAIAIAGGTLLTTLLSLVWVPTMYLLLMTK 1011 I + GG + TLL++ +VP ++++ Sbjct: 1000 NAVGIGVMGGMVSATLLAIFFVPVFFVVIRRC 1031
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.0 bits (67), Expect = 0.037 Identities = 37/236 (15%), Positives = 80/236 (33%), Gaps = 11/236 (4%) Query: 393 QTSVQSIEQQASKAQRIAKQNGEEAQALMQQTDQIATAIEEMSTSIRDVANHAQEGANQN 452 +V+ EQ A++ ++ +EA++ ++ Q + S + +E A Sbjct: 1048 SKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVE 1107 Query: 453 QQVDIAAKEGQQQQTRLVQDLLKLSQQLNNSHQAVDKVSQESEAISKVTEVINSIAEQTN 512 ++ + + Q+ V + Q+ + + Q + ++E++ T I QTN Sbjct: 1108 KEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDP----TVNIKEPQSQTN 1163 Query: 513 LLA--LNAAIEAARAGEQGRGFAVVADEVRTLAKRTQTSILEIGQTIDKLQTQVKTTTSQ 570 A A E + EQ V + + E T ++++ Sbjct: 1164 TTADTEQPAKETSSNVEQ-----PVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNK 1218 Query: 571 MAQSHQLGIASANQGEETGHQLEEINRRIAELAISSRNIASATEQQSSVAQEITHN 626 H+ + S E +A ++S N + + AQ + N Sbjct: 1219 PKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALN 1274
>OMS28PORIN#OMS28 porin signature. Length = 257 Score = 30.9 bits (69), Expect = 0.031 Identities = 32/138 (23%), Positives = 61/138 (44%), Gaps = 11/138 (7%) Query: 138 VLNDFAKADVLFKRTEPAPFKSVNVLAEGRRAL------EVANVEMGLALAEDEIDYLVE 191 +++D AK V+ + K ++AEG + V + +++A E +L+E Sbjct: 102 LMSDVAKGTVVASQEATIVAKCSGMVAEGANKVVEMSKKAVQETQKAVSVA-GEATFLIE 160 Query: 192 NFVRLNRNPNDIELMMFAQ--ANSEHCRHKIFNADWTIDGKAQ-PKSLFKMIKNTFEVTP 248 + LN++PN+ EL + + A E + + ++ +D Q + + M+ Sbjct: 161 KQIMLNKSPNNKELELTKEEFAKVEQVKETLMASERALDETVQEAQKVLNMVNGLNPSNK 220 Query: 249 DHVLSAYKDNAAVMEGSV 266 D VL A KD A + V Sbjct: 221 DQVL-AKKDVAKAISNVV 237
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.1 bits (156), Expect = 1e-12 Identities = 27/124 (21%), Positives = 47/124 (37%), Gaps = 2/124 (1%) Query: 680 QSLTVLAVDDNFANLKLIDTLLNELVTTVIAVNSGEEAVKQAKTRTFDLIFMDIQMPGTD 739 T+L DD+ A +++ L+ V ++ + DL+ D+ MP + Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 740 GISATKQIRQGSMNRNTPIIAVTAHAIAEERELILGSGMDGYLPKPIDEAALKAEINRWI 799 +I+ + P++ ++A G YLPKP D L I R + Sbjct: 62 AFDLLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119 Query: 800 TRPK 803 PK Sbjct: 120 AEPK 123
>FLAGELLIN#Flagellin signature. Length = 507 Score = 29.2 bits (65), Expect = 0.010 Identities = 14/48 (29%), Positives = 22/48 (45%), Gaps = 1/48 (2%) Query: 94 AMDAVVALSTLLGAIQTNLEEDITNISKLSSSTVANYIETISDVDLTD 141 A+ V A+ + LGAIQ + ITN+ ++ + I D D Sbjct: 427 ALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSAR-SRIEDADYAT 473
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 38.1 bits (88), Expect = 9e-05 Identities = 45/247 (18%), Positives = 81/247 (32%), Gaps = 19/247 (7%) Query: 138 KSEHQLTLLDSYANHRLLIDTVTASYQRCKQIEAELKQLEASQHERIARKQLVQYQVEEL 197 SE + + A L + + A++K LEA + ARK ++ +E Sbjct: 108 LSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGA 167 Query: 198 DEFDLKVGEFEEIEQEHKRLANGTELVDSCQASLYLLTDGEESNIESLLNKVVSLAENLQ 257 + K L +++ QA L + + + + L+ Sbjct: 168 MN------FSTADSAKIKTLEAEKAALEARQAEL----EKALEGAMNFSTADSAKIKTLE 217 Query: 258 SYDPALTNVSTMLNEALIQVQESAGELQHYLSKLELDPAYFAYLEERLSKAMQLARKHHV 317 + AL L +AL + + LE A A LE R ++ + Sbjct: 218 AEKAALAARKADLEKALEGAMNFSTADSAKIKTLE---AEKAALEARQAELEKALEGAMN 274 Query: 318 SPDKLAEHHLALKAELTTLDDDETKLEEIQLQVEASKSAYLANAQKLSQSRARYAK---E 374 + L+AE L+ ++ LE Q + + + + L SR + E Sbjct: 275 FSTADSAKIKTLEAEKAALEAEKADLEH---QSQVLNANRQSLRRDLDASREAKKQLEAE 331 Query: 375 LDKLVTQ 381 KL Q Sbjct: 332 HQKLEEQ 338 Score = 33.9 bits (77), Expect = 0.002 Identities = 38/233 (16%), Positives = 79/233 (33%), Gaps = 7/233 (3%) Query: 131 HAHHAMLKSEHQLTLLDSYANHRLLIDTVTASYQRCKQIEAELKQLEASQHE-RIARKQL 189 A A L++ + ++ TA + K +EAE L A + + A + Sbjct: 182 EAEKAALEARQA----ELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGA 237 Query: 190 VQYQVEELDEFDLKVGEFEEIEQEHKRLANGTELVDSCQASLYLLTDGEESNIESLLNKV 249 + + + + E +E L E + + E+ +L + Sbjct: 238 MNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEK 297 Query: 250 VSLAENLQSYDPALTNVSTMLNEALIQVQESAGELQHYLSKLELDPAYFAYLEERLSKAM 309 L Q + ++ L+ + ++ E Q + ++ A L L + Sbjct: 298 ADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASR 357 Query: 310 QLARKHHVSPDKLAEHHLALKAELTTLDDDETKLEEIQLQVEASKSAYLANAQ 362 + ++ KL E + +A +L D E + QVE + AN++ Sbjct: 358 EAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEE--ANSK 408
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 27.4 bits (61), Expect = 0.025 Identities = 9/39 (23%), Positives = 16/39 (41%) Query: 71 LSDLAAMGAEPAWMTLALTLPEVNETWLSGFSEGLFEAA 109 + DL G + ++ L L+ + G GLF+ Sbjct: 1 MDDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTV 39
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 51.4 bits (123), Expect = 3e-09 Identities = 21/108 (19%), Positives = 47/108 (43%), Gaps = 3/108 (2%) Query: 50 PLAQSVSLIGKLA-ADRAVVIAPQVTGKIKQIAVVSNQAVKKGQLLIELDDMKAQAAVAE 108 + + GKL + R+ I P +K+I V ++V+KG +L++L + A+A + Sbjct: 79 QVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLK 138 Query: 109 ANAFLNDETRKLKEFEKLISRNAITQTEIDAQKASVDIARARLASAQA 156 + L +L++ I +I ++ K + ++ + Sbjct: 139 TQSSL--LQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEV 184 Score = 44.8 bits (106), Expect = 3e-07 Identities = 42/246 (17%), Positives = 88/246 (35%), Gaps = 33/246 (13%) Query: 51 LAQSVSLIGKLAADRAVVIAPQVTGKIKQIAVVSNQ-----AVKKGQLLIELDDMKAQAA 105 Q + K A+R V+A ++ V ++ ++ Q + + ++ + Sbjct: 202 KYQKELNLDKKRAERLTVLA-RINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENK 260 Query: 106 VAEANAFLNDETRKLKEFEKLISRNAITQTEIDAQ----------KASVDIA--RARLAS 153 EA L +L++ E I + + + +I LA Sbjct: 261 YVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAK 320 Query: 154 AQADLHYHSLIAPFAGQT-GLINFSEGKMVSTGNELMTL-DDLSSMRLDLQVPEHFLSQI 211 + + AP + + L +EG +V+T LM + + ++ + V + I Sbjct: 321 NEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFI 380 Query: 212 SIGMPVSSTSRAWPGETF---IGKVVAIDP-RVNEETLNL--KIRVQFE-------NTDN 258 ++G A+P + +GKV I+ + ++ L L + + E N + Sbjct: 381 NVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCLSTGNKNI 440 Query: 259 RLKPGM 264 L GM Sbjct: 441 PLSSGM 446
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 781 bits (2019), Expect = 0.0 Identities = 309/1032 (29%), Positives = 518/1032 (50%), Gaps = 28/1032 (2%) Query: 3 LSDVSVKRPVVAIVLSLLLCVFGLVSFTKLSVREMPDVESPVVTVSTSYSGASAAIMESQ 62 +++ ++RP+ A VL+++L + G ++ +L V + P + P V+VS +Y GA A ++ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 63 ITKTLEDELTGISGIDEITSTT-RNGSSRITVKFLLGWNLTEGVSDVRDAVARAQRRLPE 121 +T+ +E + GI + ++ST+ GS IT+ F G + V++ + A LP+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 122 DANDPVVSKDNGSGEPSVYVNLSSSVMDRTQ--LTDYAQRVLEDRFSLISGVSSISISGG 179 + +S + S + S TQ ++DY ++D S ++GV + + G Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 180 LYKVMYVKLRPEQMAGRNVTVTDITSALRKENIETPGGQVRNDTTV------MSVRTKRL 233 Y + + L + + +T D+ + L+ +N + GQ+ + S+ + Sbjct: 181 QYAMR-IWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 234 YYTPKDFDYLVVRTASDGTPIYLKDVADVAVGAQNENSTFKSDGIVNLSLGVITQSDANP 293 + P++F + +R SDG+ + LKDVA V +G +N N + +G LG+ + AN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 294 LVVAQEVHKEVDKIQDFLPEGTSLVVDFDSTVFIDRSINEVYNTLYVTGALVVLVLYIFI 353 L A+ + ++ ++Q F P+G ++ +D+T F+ SI+EV TL+ LV LV+Y+F+ Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 354 GQVRATLIPAVTVPVSLISAFIAANMFGYSINLLTLMALILAIGLVVDDAIVVVENIFHH 413 +RATLIP + VPV L+ F FGYSIN LT+ ++LAIGL+VDDAIVVVEN+ Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 414 I-EKGEEPLLAAYKGTREVGFAVVATTAVLVMVFLPISFMEGMVGLLFTEFSVMLAVSVL 472 + E P A K ++ A+V VL VF+P++F G G ++ +FS+ + ++ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 473 FSSLIALTLTPVLSSKLLKANVK-----PNRFNRFVDRGFARMEKLYHVGVTHAIRFRLL 527 S L+AL LTP L + LLK F + + F Y V + Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 528 APLVILACIGGSVWLMQQVPAQLAPQEDRGVLYAFVKGAEGTSYNRMTANMDIVEDRLMP 587 L+ + G V L ++P+ P+ED+GV ++ G + R +D V D + Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 588 LLGQGVLRSFSVQAPAFGGRAGDQTGYVIMQLEDWEHRNVTAQQALGIISKA---LKDIP 644 V F+V +F G+ G + L+ WE RN A +I +A L I Sbjct: 600 NEKANVESVFTVNGFSFSGQ-AQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIR 658 Query: 645 DVMVRPM-MPGFRGQ-SSEPVQFVL---GGSDYAELFKWAQVLKEQANASP-MMEGADLD 698 D V P MP ++ F L G + L + L A P + + Sbjct: 659 DGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPN 718 Query: 699 YAETTPELIVTVDKERAAELGISVDDVSQTLEVMLGGRKETTYVDRGEEYDVYLRGDENS 758 E T + + VD+E+A LG+S+ D++QT+ LGG ++DRG +Y++ D Sbjct: 719 GLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKF 778 Query: 759 FNNVGDLSQIYMRSAKGELVTLDTVTHIEEVASAQRLSHTNKQKSITLKANISKGYTLGE 818 D+ ++Y+RSA GE+V T V + RL N S+ ++ + G + G+ Sbjct: 779 RMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGD 838 Query: 819 ALTFLENKSIELLPKDISIGYTGESKDFKENQSSIFIVFGLALLVAYLVLAAQFESFINP 878 A+ +EN + + LP I +TG S + + + + ++ +V +L LAA +ES+ P Sbjct: 839 AMALMENLASK-LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIP 897 Query: 879 LVVMFTVPMGVFGGFLGLLVTSQGINIYSQIGMIMLIGMVTKNGILIVEFANQLRDR-GL 937 + VM VP+G+ G L + +Q ++Y +G++ IG+ KN ILIVEFA L ++ G Sbjct: 898 VSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGK 957 Query: 938 ALDKAIIDASTRRLRPILMTAFTTLVGAIPLIFSTGAGSESRIAVGTVVFFGMAFATFVT 997 + +A + A RLRPILMT+ ++G +PL S GAGS ++ AVG V GM AT + Sbjct: 958 GVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLA 1017 Query: 998 LFVIPAMYRLIS 1009 +F +P + +I Sbjct: 1018 IFFVPVFFVVIR 1029
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 60.3 bits (146), Expect = 4e-12 Identities = 60/263 (22%), Positives = 114/263 (43%), Gaps = 26/263 (9%) Query: 7 LWLAVLLMMFPQIMETIYSPALPDIAEHFAVPISAAAQTLSVYFVAFAIGVFCWGRLADV 66 +WL +L + E + + +LPDIA F P ++ + + + F+IG +G+L+D Sbjct: 17 IWLCILSFFSV-LNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQ 75 Query: 67 IGRRKAMLAGLVCYAIGSAFALLV-SDFSLLLMARVLSAFGAA----VGSVITQTMMRDS 121 +G ++ +L G++ GS + S FSLL+MAR + GAA + V+ + Sbjct: 76 LGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKE 135 Query: 122 YSGEELAKVFSVMGMSFGISPVIGLLLGSVLSAFWGYQGVFVVLMSSAIVLLFLSVKSLP 181 G+ + S++ M G+ P IG ++ + W Y +++ I+ + +K L Sbjct: 136 NRGKAFGLIGSIVAMGEGVGPAIGGMIAHYI--HWSY---LLLIPMITIITVPFLMKLLK 190 Query: 182 ETKPAHTQTIAIGELAIKMLSDRGIIKNTLLVAAFNLMWFSYFSLAPFMFEAQ------- 234 + I + + + GI+ L ++++ + L+ +F Sbjct: 191 KEV-RIKGHFDIKGIILMSV---GIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDP 246 Query: 235 ----GLSTLIFGMSGLLLGFGAF 253 GL I M G+L G F Sbjct: 247 FVDPGLGKNIPFMIGVLCGGIIF 269
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1032 bits (2670), Expect = 0.0 Identities = 420/1043 (40%), Positives = 639/1043 (61%), Gaps = 18/1043 (1%) Query: 2 LSQFFIKRPIFAAVLSLLFFITGAIAVWQLPITEYPEVVPPTVVVTANYPGANPKVIAET 61 ++ FFI+RPIFA VL+++ + GA+A+ QLP+ +YP + PP V V+ANYPGA+ + + +T Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 62 VASPLEQEINGVEDMLYMSSQATSDGRMTLTITFAIGTDVDRAQTQVQSRVDRAMPRLPQ 121 V +EQ +NG+++++YMSS + S G +T+T+TF GTD D AQ QVQ+++ A P LPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 122 EVQRLGIVTEKSSPDLTMVVHLLSPDNRYDMLYLSNYAALNVKDELARIKGVGAVRLFGA 181 EVQ+ GI EKSS MV +S + +S+Y A NVKD L+R+ GVG V+LFG Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG- 179 Query: 182 GEYSLRIWLDPNKVSALGMSPSDIIAAVREQNQQAAAGSLGAQPSGNA-DFQLLINVKGR 240 +Y++RIWLD + ++ ++P D+I ++ QN Q AAG LG P+ I + R Sbjct: 180 AQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 241 LTELSEFEDIIIKVGQNGEVIRLKDVARVELGAISYALRSLLDNKDAVAIPVFQASGSNA 300 EF + ++V +G V+RLKDVARVELG +Y + + ++ K A + + A+G+NA Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 301 IQISDDVRAEMARLAKSFPEGLQYEIVYDPTVFVRGSIEAVVKTLLEAVLLVVLVVVLFL 360 + + ++A++A L FP+G++ YD T FV+ SI VVKTL EA++LV LV+ LFL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 361 QTWRASIIPLVAVPVSLVGTFAFMHLMGFSLNALSLFGLVLAIGIVVDDAIVVVENVERN 420 Q RA++IP +AVPV L+GTFA + G+S+N L++FG+VLAIG++VDDAIVVVENVER Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 421 IAS-GLSPIAATQKAMKEVTGPIVATTLVLAAVFIPTAFMSGLTGQFYKQFALTITISTF 479 + L P AT+K+M ++ G +V +VL+AVFIP AF G TG Y+QF++TI + Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 480 ISAINSLTLSPALSALLLKGHDAPKDALTRLMDKLFGGWLFTPFNRLFNRASEGYGYLVR 539 +S + +L L+PAL A LLK A G F FN F+ + Y V Sbjct: 480 LSVLVALILTPALCATLLKPVSAE--------HHENKGGFFGWFNTTFDHSVNHYTNSVG 531 Query: 540 KVIRFGGIIGLVYLGMVALTGVQFVNTPTGYVPGQDKQYLVAFAQLPDAASLERTDVVIK 599 K++ G L+Y +VA V F+ P+ ++P +D+ + QLP A+ ERT V+ Sbjct: 532 KILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLD 591 Query: 600 KMSDIALNH--PGVAHSIAFPGLSINGFTNSPNSGVVFVALDDFELRKSPELSANAIAGQ 657 +++D L + V G S +G + N+G+ FV+L +E R E SA A+ + Sbjct: 592 QVTDYYLKNEKANVESVFTVNGFSFSG--QAQNAGMAFVSLKPWEERNGDENSAEAVIHR 649 Query: 658 LNQQFAGIQDAFIAIFPPPPVQGLGTIGGFRLQIQDRANLGYEALYQVTQQVMYKAWADP 717 + I+D F+ F P + LGT GF ++ D+A LG++AL Q Q++ A P Sbjct: 650 AKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHP 709 Query: 718 -QLAGIFSSYQVNVPQLELDIDRTKAKQQAVSLDQIFQTLQTYMGSTYVNDFNRFGRTYQ 776 L + + + Q +L++D+ KA+ VSL I QT+ T +G TYVNDF GR + Sbjct: 710 ASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKK 769 Query: 777 VNMQADEAFRQSPQQISQLKVPNVNGDMIPLGSFINVSQSAGPDRVMHYNGFTTAEINGG 836 + +QAD FR P+ + +L V + NG+M+P +F G R+ YNG + EI G Sbjct: 770 LYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGE 829 Query: 837 PAPGVSSGQAQAAIEKILAETLPIGMTYEWTELTYQQILAGNTGLLVFPLVIVLVFMVLA 896 APG SSG A A +E + ++ LP G+ Y+WT ++YQ+ L+GN + + V+VF+ LA Sbjct: 830 AAPGTSSGDAMALMENLASK-LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLA 888 Query: 897 AQYESLSLPLAIILIIPMTLLSALSGVLLYGGDNNIFTQIGLIVLVGLATKNAILIVEFA 956 A YES S+P++++L++P+ ++ L L+ N+++ +GL+ +GL+ KNAILIVEFA Sbjct: 889 ALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFA 948 Query: 957 KEKQDH-GMEVMESILEAARLRLRPILMTSIAFIMGVVPMVFSTGAGAEMRQAMGVAVFA 1015 K+ + G V+E+ L A R+RLRPILMTS+AFI+GV+P+ S GAG+ + A+G+ V Sbjct: 949 KDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMG 1008 Query: 1016 GMIGVTIFGLILTPLFYYSLVKR 1038 GM+ T+ + P+F+ + + Sbjct: 1009 GMVSATLLAIFFVPVFFVVIRRC 1031
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 46.0 bits (109), Expect = 2e-07 Identities = 34/181 (18%), Positives = 68/181 (37%), Gaps = 27/181 (14%) Query: 6 TLRTLMLTTVAAFVLSACGEPEVLQGQAPAAPKVDVAQVLQERVTEWDEFTGRLQAPESV 65 +M V AF+LS G +V++ ++T +GR S Sbjct: 60 VAYFIMGFLVIAFILSVLG-------------QVEIVATANGKLT----HSGR-----SK 97 Query: 66 TLVPRVSGYIASVNFKEGALVKKGDVLFRIDASVFEAEVARLKADLASALSA---DQLAT 122 + P + + + KEG V+KGDVL ++ A EA+ + ++ L A Q+ + Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILS 157 Query: 123 NDLERARKLFVQKAVSAELLDTRESNKRQTTAAVASVKAALLR--AELDLDYTQVRAPID 180 +E + ++ + E + T+ + + + +L+ + RA Sbjct: 158 RSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERL 217 Query: 181 G 181 Sbjct: 218 T 218 Score = 39.0 bits (91), Expect = 2e-05 Identities = 21/102 (20%), Positives = 41/102 (40%), Gaps = 10/102 (9%) Query: 101 EAEVARLKADLASALSADQLATNDLERARKLFVQKAVSAELLDTRESNKRQTTAAVASVK 160 E+ K+ L S A + + +LF + + +L RQTT + + Sbjct: 265 VNELRVYKSQLEQIESEILSAKEEYQLVTQLF-KNEILDKL--------RQTTDNIGLLT 315 Query: 161 AALLRAELDLDYTQVRAPIDGRASYANV-TAGNYVSAGQSVL 201 L + E + +RAP+ + V T G V+ ++++ Sbjct: 316 LELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLM 357
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 58.5 bits (141), Expect = 7e-13 Identities = 35/160 (21%), Positives = 61/160 (38%), Gaps = 5/160 (3%) Query: 23 LAKALEVFWRKGFEGTSLTDLTQAMGINKPSLYAAFGNKEQLFLKAIELYEQRPCAFFYP 82 L AL +F ++G TSL ++ +A G+ + ++Y F +K LF + EL E Sbjct: 17 LDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELE 76 Query: 83 SLEK--ETAYQVVESMLLGAATSLVDENQPHGCLIVQGALACSEAGQAIKETLITRRRDG 140 K V+ +L+ S V E + + + C G+ R Sbjct: 77 YQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHK-CEFVGEMAVVQQAQRNLCL 135 Query: 141 E--QALCERLQRAKDEGDLPADADPLLLARYVGTVLQGMA 178 E + + L+ + LPAD A + + G+ Sbjct: 136 ESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLM 175
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.7 bits (66), Expect = 0.021 Identities = 11/34 (32%), Positives = 16/34 (47%) Query: 30 MIGLLGPSGSGKTTLLRIIAGLEGADSGHIHFGN 63 + L G G GK+TL+ + GL+ H G Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGT 631
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 31.3 bits (71), Expect = 0.005 Identities = 10/28 (35%), Positives = 13/28 (46%), Gaps = 2/28 (7%) Query: 17 GCGELGKEVAIELQRLGVEVIGVD--RY 42 G L K V LQ+ G V+G +Y Sbjct: 62 GWATLDKAVGGILQQQGWPVVGWSSLKY 89
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 29.2 bits (65), Expect = 0.036 Identities = 30/137 (21%), Positives = 50/137 (36%), Gaps = 19/137 (13%) Query: 322 PEVLQSFVKKLHTLADPNLRGMIWFRLPLEGDKRMWPLSTLIAVAKQQPLAPQVELQMVS 381 P V++ + L L MI++R+ L + + + A A+QQP+ Sbjct: 11 PSVIRRILFYLLMLLFCQQLAMIFWRIGLPDNAPVSSVQITPAQARQQPVTL-------- 62 Query: 382 QPMTELAQEPAPNAKQTDQQTKANKPPQTTLFQLVLVNKGNLAGKVPSQLSLAAQSCSGY 441 T P N ++ + P + L L G +AG S+ S+A S Sbjct: 63 NDFTLFGVSPEKNKAGALDASQMSNLPPS---TLNLSLTGVMAGDDDSR-SIAIISKDNE 118 Query: 442 -------DAQNGYIAKL 451 + GY AK+ Sbjct: 119 QFSRGVNEEVPGYNAKI 135
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 29.9 bits (67), Expect = 0.020 Identities = 32/174 (18%), Positives = 65/174 (37%), Gaps = 28/174 (16%) Query: 103 ENSELSEAQLVLVNSLRDAPSLAQAEQIAAQLKDTLPPALTWYSLGAMAFDAKEYDKASN 162 E ++ E QL + + L+ ++A +I++ + L YSL + + +Y+ A Sbjct: 4 ETTDTQEYQLAMESFLKGGGTIAMLNEISSDTLEQL------YSLAFNQYQSGKYEDAHK 57 Query: 163 YFKKVIVLPAS------------ERAGRSLWALYSLSRIELLQSK-PSPDNAHFAKANAY 209 F+ + VL + G+ A++S S ++ K P F A Sbjct: 58 VFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKEPRF---PFHAAECL 114 Query: 210 LMQLQAEVIQGAADPLRLSLA------SLGEQAYILLHQGQPSIEIAHEEYEAP 257 L + + + + +A L + +L + E+ HE + P Sbjct: 115 LQKGELAEAESGLFLAQELIADKTEFKELSTRVSSMLEAIKLKKEMEHECVDNP 168
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 97.3 bits (242), Expect = 4e-26 Identities = 37/123 (30%), Positives = 62/123 (50%), Gaps = 11/123 (8%) Query: 116 LNMPNEVTFGVDQTELSDGAKRVLNSVALVAKEYSKT--QLNVLGYTDSSGSDSYNLRLS 173 + ++V F ++ L + L+ + + VLGYTD GSD+YN LS Sbjct: 215 FTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLS 274 Query: 174 QVRASEVGNYLMSKGVASARVKSKGMGEASPIASNANAEGR---------AQNRRVEIVL 224 + RA V +YL+SKG+ + ++ ++GMGE++P+ N + A +RRVEI + Sbjct: 275 ERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEV 334 Query: 225 TPT 227 Sbjct: 335 KGI 337
>PF04183#IucA / IucC family Length = 580 Score = 26.0 bits (57), Expect = 0.014 Identities = 8/39 (20%), Positives = 15/39 (38%), Gaps = 3/39 (7%) Query: 5 NHSLKPDVIFEVKVKGRLLSDVARQYGLSAKSVYQWVRE 43 H L+ V R +S + + G+ + YQ + Sbjct: 477 IHDLQTGHFVTV---LRFISPLMVRLGVPERRFYQLLAA 512
>PF06580#Sensor histidine kinase Length = 349 Score = 43.7 bits (103), Expect = 1e-06 Identities = 27/147 (18%), Positives = 56/147 (38%), Gaps = 17/147 (11%) Query: 410 INEGVSTAYVQLRELLSTFRLTIKEPNLKN-AMEAMLEQLRANTDI-------KIHLDYK 461 I E + A L L R +++ N + ++ L + + + ++ + + Sbjct: 186 ILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQ 245 Query: 462 LSPQWLEAKQHIHILQITREATLNAIKHA-----NASHINIRCYKDDRGMVNISVSDNGV 516 ++P ++ + ++Q E N IKH I ++ KD+ G V + V + G Sbjct: 246 INPAIMDVQVPPMLVQTLVE---NGIKHGIAQLPQGGKILLKGTKDN-GTVTLEVENTGS 301 Query: 517 GIGHIKERDQHFGIGIMHERASKLDGE 543 + G+ + ER L G Sbjct: 302 LALKNTKESTGTGLQNVRERLQMLYGT 328
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 59.8 bits (145), Expect = 7e-13 Identities = 26/159 (16%), Positives = 64/159 (40%), Gaps = 9/159 (5%) Query: 6 SVLVVDDHPLLRKGICQLITSDPDFSLFGEVGSGLDALSSVATDEPDIVLLDLNMKGMTG 65 ++LV DD +R + Q ++ + + + +A + D+V+ D+ M Sbjct: 5 TILVADDDAAIRTVLNQALS-RAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 66 LDTLNAMRQEGVTSRIVILTVSDAKQDVIRLLRAGADGYLLKDTEPDLLLDKLKNTMSGH 125 D L +++ +++++ + I+ GA YL K + L+ + Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG------ 116 Query: 126 RVISEEVAEYLYELKNAADEQEWVSSLTPRELQILQQLA 164 R ++E +L++ + + + + +I + LA Sbjct: 117 RALAEPKRR-PSKLEDDSQDGMPLVGRSAAMQEIYRVLA 154
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 29.8 bits (67), Expect = 0.016 Identities = 19/87 (21%), Positives = 37/87 (42%), Gaps = 9/87 (10%) Query: 229 IRTIEDLDALRDRANVTQEELLSQQSEQLNKRLYFLSLV-SVIFLPLGFLTGLLGVNIGG 287 I +E+++ + + +E + Q+ L +++V S +F+P+ F G G Sbjct: 410 IVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIY-- 467 Query: 288 IPGADNNFAFT-SFCIILVSLVALQMV 313 F+ T + L LVAL + Sbjct: 468 -----RQFSITIVSAMALSVLVALILT 489
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 30.6 bits (69), Expect = 0.011 Identities = 18/81 (22%), Positives = 27/81 (33%), Gaps = 5/81 (6%) Query: 202 DYSAALLAEALTASAVEIWTDVAGIYTTDPRLAPNAHPIAEISFNEAAEMATFGAKVLHP 261 D + LAE + A I TDV G + E+ E + G Sbjct: 216 DLAGEKLAEEVNADIFMILTDVNGAALY--YGTEKEQWLREVKVEELRKYYEEGH--FKA 271 Query: 262 ATILPAVRQQIQVFVGSSKEP 282 ++ P V I+ F+ E Sbjct: 272 GSMGPKVLAAIR-FIEWGGER 291
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 28.9 bits (64), Expect = 0.030 Identities = 33/120 (27%), Positives = 46/120 (38%), Gaps = 26/120 (21%) Query: 229 GYPVARVMKVFTEDGQSYTRVTAQPLAALDRIRYLLLIWPSPD---SGVTLPNQIPVP-- 283 G PV +V+ F D Q T V Q + P PD PN P+P Sbjct: 286 GNPV-QVVATFGRDSQGNTTVDVQ-------------VIPRPDLTPGSAEAPNAQPLPEV 331 Query: 284 -AADHPVEEAKPDAVNGA-INPQGEAQGTNATVPNATVPNTTAPNATVPNATAAPRNANG 341 A++P P+ G NP+ + P+A P+T T P++ A P NG Sbjct: 332 SPAENPANNPAPNENPGTRPNPEPDPDLN----PDAN-PDTDGQPGTRPDSPAVPDRPNG 386
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 557 bits (1438), Expect = 0.0 Identities = 314/348 (90%), Positives = 332/348 (95%), Gaps = 1/348 (0%) Query: 1 MFKKLRGIFSNDLSIDLGTANTLIYVRDEGIVLNEPSVVAIRGERNSSGQKSVAAVGTEA 60 M KK RG+FSNDLSIDLGTANTLIYV+ +GIVLNEPSVVAIR +R + KSVAAVG +A Sbjct: 1 MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDR-AGSPKSVAAVGHDA 59 Query: 61 KQMLGRTPGNIQAIRPMKDGVIADFYVTEKMLQHFIKQVHNNSFFRPSPRVLVCVPVGAT 120 KQMLGRTPGNI AIRPMKDGVIADF+VTEKMLQHFIKQVH+NSF RPSPRVLVCVPVGAT Sbjct: 60 KQMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGAT 119 Query: 121 QVERRAIRESAMGAGAREVYLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAIISLN 180 QVERRAIRESA GAGAREV+LIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVA+ISLN Sbjct: 120 QVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLN 179 Query: 181 GVVYSSSVRIGGDKFDDAIINYVRRNYGSLIGEATAERIKHTIGTAYPGDEVLEIEVRGR 240 GVVYSSSVRIGGD+FD+AIINYVRRNYGSLIGEATAERIKH IG+AYPGDEV EIEVRGR Sbjct: 180 GVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGR 239 Query: 241 NLAEGVPRSFTLNSNEILEALQEPLSGIVSAVMVALEQSPPELASDISERGMVLTGGGAL 300 NLAEGVPR FTLNSNEILEALQEPL+GIVSAVMVALEQ PPELASDISERGMVLTGGGAL Sbjct: 240 NLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGAL 299 Query: 301 LRDLDRLLMQETGIPVMVADDPLTCVARGGGKALEMIDMHGGDLFSEE 348 LR+LDRLLM+ETGIPV+VA+DPLTCVARGGGKALEMIDMHGGDLFSEE Sbjct: 300 LRNLDRLLMEETGIPVVVAEDPLTCVARGGGKALEMIDMHGGDLFSEE 347
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 31.0 bits (70), Expect = 0.002 Identities = 11/24 (45%), Positives = 17/24 (70%) Query: 8 RKHQCSRGFTLVEMVTAILILGIL 31 R RGFTL+E++ I+I+G+L Sbjct: 2 RATDKQRGFTLLEIMVVIVIIGVL 25
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 38.8 bits (90), Expect = 3e-06 Identities = 16/59 (27%), Positives = 33/59 (55%), Gaps = 4/59 (6%) Query: 25 IRQQGFTLIELVVGMLVIAIAIVM-LSSMLFPQADRAAKTLHRVKSA-ELA--HSVMNE 79 +RQ+GFTL+E+++ +L++ ++ M L + + D AA+TL R ++ + Sbjct: 1 MRQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQTLARFEAQLRFVQQRGLQTG 59
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 40.7 bits (95), Expect = 5e-07 Identities = 26/82 (31%), Positives = 43/82 (52%), Gaps = 1/82 (1%) Query: 3 KQAGFTLVELVTTIILIGILSVTVLPRLFSQSSYSAFSLRNEFMAELRQVQQKALNNTDR 62 +Q GFTL+E++ ++L+G+ + VL + SA F A+LR VQQ+ L + Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQTLARFEAQLRFVQQRGLQT-GQ 60 Query: 63 CFRVAVSTTGYQVSQFASRNSA 84 F V+V +Q +R+ A Sbjct: 61 FFGVSVHPDRWQFLVLEARDGA 82
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 49.9 bits (119), Expect = 2e-10 Identities = 18/53 (33%), Positives = 31/53 (58%), Gaps = 4/53 (7%) Query: 1 MKRQQGFTLIELVVVIIILGILAVTAAPKFINLQGDARA----SALQGLKGAI 49 +Q+GFTL+E++VVI+I+G+LA P + + A S + L+ A+ Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENAL 56
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 43.3 bits (102), Expect = 8e-08 Identities = 15/36 (41%), Positives = 27/36 (75%) Query: 4 KQNGFSLIELVIVIVILGLLAATAIPRFLNVTDDAE 39 KQ GF+L+E+++VIVI+G+LA+ +P + + A+ Sbjct: 6 KQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKAD 41
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 306 bits (786), Expect = e-103 Identities = 113/406 (27%), Positives = 201/406 (49%), Gaps = 4/406 (0%) Query: 1 MPVYQYRGRSGQGQAVTGQLDAASESAAADMLLSRGIIPLEVKAAKVAK----SFSLTQL 56 M Y Y+ QG+ G +A S A +L RG++PL V + + S L+ Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 57 FGSKVGLDELQIFTRQMYSLTRSGIPILRAIAGLSETAHSQRMKDALNDISEQLTAGRPL 116 ++ +L + TRQ+ +L + +P+ A+ +++ + + + + ++ G L Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 117 SSAMNQHPDVFDSLFVSMVHVGENTGKLEDAFIQLSGYIEREQETRRRIKAAMRYPIFVL 176 + AM P F+ L+ +MV GE +G L+ +L+ Y E+ Q+ R RI+ AM YP + Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 177 IAIGLAMVILNIMVIPKFAEMFSRFGADLPWATKVLIGTSNLFVNYWPLMLVMLLGAIIG 236 + + IL +V+PK E F LP +T+VL+G S+ + P ML+ LL + Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMA 240 Query: 237 IRYWHHTEKGEKQWDKWKLHIPAVGSIIERSTLARYCRSFSMMLSAGVPMTQALSLVADA 296 R EK + + LH+P +G I ARY R+ S++ ++ VP+ QA+ + D Sbjct: 241 FRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 297 VDNAYMHDKIVGMRRGIESGESMLRVSNQSKLFTPLVLQMVAVGEETGQIDQLLNDAADF 356 + N Y ++ + G S+ + Q+ LF P++ M+A GE +G++D +L AAD Sbjct: 301 MSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADN 360 Query: 357 YEGEVDYDLKNLTAKLEPILIGIVAVIVLILALGIYLPMWDMLNVV 402 + E + EP+L+ +A +VL + L I P+ + ++ Sbjct: 361 QDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 186 bits (473), Expect = 2e-53 Identities = 78/318 (24%), Positives = 144/318 (45%), Gaps = 28/318 (8%) Query: 236 ELKETLTAIVGDTGGGRQVVVT--PQAGLVTIRAYPNELRQVRAFLSSAESHLQRQVILE 293 ++ A + +++ Q + + A P+ + + ++ + + QV++E Sbjct: 292 TMQSEKQAAKPVAALDKNIIIKAHGQTNALIVTAAPDVMNDLERVIAQLDIR-RPQVLVE 350 Query: 294 AKILEVTLSDGYQQGIQWDNVLGHV---GNTNINFGTSAGTGLS----DKITSSLGGVTS 346 A I EV +DG GIQW N + N+ + T+ ++SSL S Sbjct: 351 AIIAEVQDADGLNLGIQWANKNAGMTQFTNSGLPISTAIAGANQYNKDGTVSSSLASALS 410 Query: 347 ------LSIKGSDFNTMISLLDTQGDVDVLSSPRVTASNNQKAVIKVGTDEYFVTDVSST 400 ++ +++ L + D+L++P + +N +A VG + +T S Sbjct: 411 SFNGIAAGFYQGNWAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVPVLT--GSQ 468 Query: 401 TVAGTTPVTTPQVELTPFFSGIALDVTPQIDKDGNVLLHVHPSVIDVKEQTKDIKVSNES 460 T +G T + + GI L V PQI++ +VLL + V V + S+ S Sbjct: 469 TTSGDNIFNTVERKTV----GIKLKVKPQINEGDSVLLEIEQEVSSVADAA-----SSTS 519 Query: 461 LELPLAQSEIRESDTVIRAASGDVVVIGGLMKSENIEVVSQVPLLGDIPFVGELFKNRSK 520 +L + R + + SG+ VV+GGL+ + +VPLLGDIP +G LF++ SK Sbjct: 520 SDLGATFN-TRTVNNAVLVGSGETVVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSK 578 Query: 521 QKKKTELIIMLKPTVVGN 538 + K L++ ++PTV+ + Sbjct: 579 KVSKRNLMLFIRPTVIRD 596
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 43.5 bits (102), Expect = 2e-07 Identities = 38/195 (19%), Positives = 74/195 (37%), Gaps = 29/195 (14%) Query: 55 LEEEIKQLSQNIPQLDWLINCIGMLHTEDKGPEKSLQTLDGDFFLDNIKLNTLPSMLLAK 114 ++E ++ + + +D L+N G+L G SL + + +N+ ++ Sbjct: 72 IDEITARIEREMGPIDILVNVAGVLRP---GLIHSLSDEE---WEATFSVNSTGVFNASR 125 Query: 115 HFSHALKQSNSARFAVISARVGSISDNRLGGWYSYRASKAALNMFLKTLSIEWQRSIKHC 174 S + S + + + + +Y +SKAA MF K L +E C Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMA---AYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 175 VVLSLHPGTTDTPLSKP------------------FQQSVPKDKLFTPEYVAQCLVGIIA 216 ++S PG+T+T + F+ +P KL P +A ++ +++ Sbjct: 183 NIVS--PGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVS 240 Query: 217 NATPTQTGTFLAYDG 231 T L DG Sbjct: 241 GQAGHITMHNLCVDG 255
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 87.2 bits (216), Expect = 1e-22 Identities = 26/129 (20%), Positives = 63/129 (48%) Query: 3 RLLIIEDDQALAGILARRLTRHGFECRLSHDASSALLVARECCPTHILLDMKLAEANGLS 62 +L+ +DD A+ +L + L+R G++ R++ +A++ ++ D+ + + N Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 63 LIVPLRNLLPKVVMVLLTGYASIATAVEAIRLGADNYLAKPVDTQTLLAAFELDVHSNNL 122 L+ ++ P + +++++ + TA++A GA +YL KP D L+ + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 123 QEDDVDDSP 131 + ++D Sbjct: 125 RPSKLEDDS 133 Score = 47.5 bits (113), Expect = 6e-09 Identities = 13/39 (33%), Positives = 22/39 (56%) Query: 135 KRLEWEHIQQVLNANQGNVSATARQLGMHRRTLQRKLLK 173 +E+ I L A +GN A LG++R TL++K+ + Sbjct: 434 AEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRE 472
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 67.9 bits (166), Expect = 4e-15 Identities = 37/158 (23%), Positives = 61/158 (38%), Gaps = 20/158 (12%) Query: 3 NIMVTGATGLLGRAVVKQLTAAGHRVI---------------ATGFSCAEAN--IHKLDL 45 +VTGA G +G V K+L AGH+V+ A A+ HK+DL Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 46 TQAIAVEAFIARERPEVIVHCAAERRPDVSEQSPEQALALNLSASQTLAKAAKQHG-AWL 104 + A E + S ++P NL+ + + + + L Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 105 LYISTDYVF-DGTTPPYAE-DAAPNPVNFYGESKLQGE 140 LY S+ V+ P++ D+ +PV+ Y +K E Sbjct: 122 LYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANE 159
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 45.2 bits (107), Expect = 2e-07 Identities = 37/202 (18%), Positives = 65/202 (32%), Gaps = 33/202 (16%) Query: 35 RWYLLLTLVIAPVVVVG--WILLRP-HLFILASGIVTT--EPLEVRAPSAGDVAAIMVKR 89 R L+ I +V+ +L + A+G +T E++ V I+VK Sbjct: 55 RRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKE 114 Query: 90 GDVLASGANILTLVDTQLGAQIQELEKQLSQLEFDHLSLNAEILTQLQQRIAVAAEGVTR 149 G+ + G +L L A + + L LQ R+ R Sbjct: 115 GESVRKGDVLLKLTALGAEADTLKTQSSL-----------------LQARLEQT-----R 152 Query: 150 QDGLLDSFERYQRQGVVPTAD--MAAVLQAHTASKMALEQAKVDLMQARQGQKTELLAGA 207 L S E + + + V + +L + + Q ++ QK L Sbjct: 153 YQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKK 212 Query: 208 IAQSKYNIELQLARLKAQESQL 229 A+ LAR+ E+ Sbjct: 213 RAE----RLTVLARINRYENLS 230
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 92.3 bits (229), Expect = 2e-24 Identities = 35/118 (29%), Positives = 54/118 (45%), Gaps = 12/118 (10%) Query: 77 NVLFPNNSAYIAPEYYPQIEEVAIFLRQY--PTTKVTIEGHTSRTGTDETNKELSQERAN 134 +VLF N A + PE ++++ L V + G+T R G+D N+ LS+ RA Sbjct: 220 DVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQ 279 Query: 135 AVTAVLAERFGIDRSRLTAIGYGSSRPIVLEQTPEAEIR---------NRRVVAEVTG 183 +V L + GI +++A G G S P+ + R +RRV EV G Sbjct: 280 SVVDYLISK-GIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKG 336
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 58.5 bits (141), Expect = 5e-13 Identities = 34/141 (24%), Positives = 57/141 (40%), Gaps = 6/141 (4%) Query: 2 DSKRDLILRSAEKIIATEGLHNLSMQKLAVDAGVAAGTIYRYFKDKEDLIIKLRKDVLQQ 61 R IL A ++ + +G+ + S+ ++A AGV G IY +FKDK DL ++ + Sbjct: 10 QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESN 69 Query: 62 IASKLLENIDE--GSFDEKFRRLWFNIVELGREQSHANLSFAQYSHL---PGVDAPEHQA 116 I LE + G R + +++E + L H G A QA Sbjct: 70 IGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQA 129 Query: 117 FEREIFQPLHQLFEQAKGQGV 137 +R + + EQ + Sbjct: 130 -QRNLCLESYDRIEQTLKHCI 149
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 44.4 bits (105), Expect = 5e-07 Identities = 23/130 (17%), Positives = 33/130 (25%), Gaps = 35/130 (26%) Query: 71 TISNELAGRVTSINFENGSRVEKGQLLAELDAKVERANLKSKMVQLPAAEADFKRLSKLY 130 I V I + G V KG +L +L A A+ L A + R L Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILS 157 Query: 131 -----------------------------------AQKSVSKQDLDNSESKYLALQADIE 155 Q S + E +A+ Sbjct: 158 RSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERL 217 Query: 156 SLKATIERRE 165 ++ A I R E Sbjct: 218 TVLARINRYE 227 Score = 43.7 bits (103), Expect = 8e-07 Identities = 37/253 (14%), Positives = 75/253 (29%), Gaps = 71/253 (28%) Query: 88 GSRVEKGQLLAELDAKVERANLKSKMVQLPAAEADFKRLSKLYAQKSVSKQDLDNSESKY 147 + + AE + R N ++ S L +++++K + E+KY Sbjct: 204 QKELNLDKKRAERLTVLARINRYEN--LSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKY 261 Query: 148 LALQADIESLKATIER-------------------------------------------- 163 + ++ K+ +E+ Sbjct: 262 VEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKN 321 Query: 164 ------REISAPFSGLVGIRNIN-LGEYLQPGT---DIVRLEDISTMKIRFTIPQTQLPR 213 I AP S V ++ G + IV +D T+++ + + Sbjct: 322 EERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDD--TLEVTALVQNKDIGF 379 Query: 214 IAVGQKIHVFVDSYPEQ---PFEGEIAAIEP--------AVFYQSGLIQVQARIP--NDN 260 I VGQ + V+++P G++ I + + + + + N N Sbjct: 380 INVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCLSTGNKN 439 Query: 261 AKLRSGMFARVSI 273 L SGM I Sbjct: 440 IPLSSGMAVTAEI 452
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 789 bits (2038), Expect = 0.0 Identities = 318/1037 (30%), Positives = 539/1037 (51%), Gaps = 34/1037 (3%) Query: 5 DIFIRRPVLAASISFLLLLLGFNALNSMQVREYPKMTNTVVTVSTSYYGADANLIQGFIT 64 + FIRRP+ A ++ +L++ G A+ + V +YP + V+VS +Y GADA +Q +T Sbjct: 3 NFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVT 62 Query: 65 QPLEQALAQADNVDFMTSESF-LGTSKISVYMKLNTDPNGALADILAKVNSVRSQLPKEA 123 Q +EQ + DN+ +M+S S G+ I++ + TDP+ A + K+ LP+E Sbjct: 63 QVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEV 122 Query: 124 EDPSVEMSTGSQTSVLYISFFSDQINSSQ--LTDYLERVVKPQLFTIDGVAKVNLYGGIK 181 + + + S + ++ F SD ++Q ++DY+ VK L ++GV V L+G + Sbjct: 123 QQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA-Q 181 Query: 182 YAMRIWLDPARMGAFNLSASDVMQVLQANNYQSAVGQTNSVYTL------FNGTADTQVA 235 YAMRIWLD + + L+ DV+ L+ N Q A GQ L + A T+ Sbjct: 182 YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK 241 Query: 236 TIEELKRLVI-GSKDGLVVRLGDIADVSLEKSHDIYRALANGKEAVVIGLDVTPTANPLT 294 EE ++ + + DG VVRL D+A V L + A NGK A +G+ + AN L Sbjct: 242 NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALD 301 Query: 295 VAADTRALLPEIERNLPPSIESSILYDSSLAIDESIKEVVKTIGEAAIIVIVVITLFLGS 354 A +A L E++ P ++ YD++ + SI EVVKT+ EA ++V +V+ LFL + Sbjct: 302 TAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQN 361 Query: 355 LRAVVIPIVTIPLSLIGVAIIMQMFGFTLNLMTLLAMVLAIGLVVDDAIVVVENVDRHIK 414 +RA +IP + +P+ L+G I+ FG+++N +T+ MVLAIGL+VDDAIVVVENV+R + Sbjct: 362 MRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 415 LGESPFRAAII-GTREIAVPVISMTITLAAVYAPIALMGGITGSLFKEFALTLAGSVFIS 473 + P + A +I ++ + + L+AV+ P+A GG TG+++++F++T+ ++ +S Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 474 GIVALTLSPMMCAKILKP-----HTTPNRFEMGVENFLTGLTRRYSNMLDAVMLHRPVIV 528 +VAL L+P +CA +LKP H F Y+N + ++ + Sbjct: 482 VLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYL 541 Query: 529 AFAIIVFASLPVLFKFIPSELAPNEDKGVVMMMGTAPSTANLDYIQANMGLVTDMIKAQP 588 ++ A + VLF +PS P ED+GV + M P+ A + Q + VTD Sbjct: 542 LIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNE 601 Query: 589 ESAASLAF----VGVPSSSQAFGIA--PLVPWSERDKSQKQMQEFFAK---EVKRIPGMA 639 ++ F +Q G+A L PW ER+ + + + E+ +I Sbjct: 602 KANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGF 661 Query: 640 ITTFQMPE--LPGASSGLPIQFVITTSNSFASLFQIGTSVLEKVQKSPLFVYSEI-NLKF 696 + F MP G ++G + + +L Q +L + P + S N Sbjct: 662 VIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLE 721 Query: 697 DSGTMKLHIKRDLAGTYGVTMQDIGITLATMMSDGYVNRINLDGRSYEVIPQVERKLRAN 756 D+ KL + ++ A GV++ DI T++T + YVN GR ++ Q + K R Sbjct: 722 DTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRML 781 Query: 757 PESLANYYVKAADGKSIPLSSLVEIEMVAEPRSLPHFNQMNALTVGGVASPGVAIGDAIS 816 PE + YV++A+G+ +P S+ V L +N + ++ + G A+PG + GDA++ Sbjct: 782 PEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMA 841 Query: 817 FLQNIGDNELPKGYSYDFLGEARQFVTEGSALYATFLLAIAIIFLVLASQFESLKDPLVI 876 ++N+ ++LP G YD+ G + Q G+ A ++ ++FL LA+ +ES P+ + Sbjct: 842 LMENL-ASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900 Query: 877 LVSVPLAISGALIVLGWTHVFGLAKINIYTQVGLITLVGLITKHGILMCEVAKEEQLHRG 936 ++ VPL I G L+ + K ++Y VGL+T +GL K+ IL+ E AK+ G Sbjct: 901 MLVVPLGIVGVLLAATLFNQ----KNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEG 956 Query: 937 LSKLEAIKLAATIRLRPILMTTAAMIAGLLPLLFASGAGAVARFNIGVVIVAGLSIGTIF 996 +EA +A +RLRPILMT+ A I G+LPL ++GAG+ A+ +G+ ++ G+ T+ Sbjct: 957 KGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLL 1016 Query: 997 TLFVLPVIYTYLAEKHE 1013 +F +PV + + + Sbjct: 1017 AIFFVPVFFVVIRRCFK 1033
>PF06580#Sensor histidine kinase Length = 349 Score = 24.8 bits (54), Expect = 0.049 Identities = 7/29 (24%), Positives = 14/29 (48%) Query: 46 MVSREEFEVQQHVLLKTREKLEALQAQVN 74 + E + + + +L AL+AQ+N Sbjct: 143 NYKQAEIDQWKMASMAQEAQLMALKAQIN 171
>TACYTOLYSIN#Bacterial thiol-activated pore-forming cytolysin signature. Length = 574 Score = 31.1 bits (70), Expect = 0.003 Identities = 16/68 (23%), Positives = 29/68 (42%), Gaps = 3/68 (4%) Query: 30 DYMPSNKTTYLKKIMNMGDSTAFI---KISINEIKYDENGQPYEVPEQEAENRALIASPS 86 +Y+ + T Y +N+ A++ +I +EI YD+ G+ + N SP Sbjct: 454 EYVETTSTEYTSGKINLSHQGAYVAQYEILWDEINYDDKGKEVITKRRWDNNWYSKTSPF 513 Query: 87 RLIIPAKG 94 +IP Sbjct: 514 STVIPLGA 521
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 54.5 bits (131), Expect = 1e-09 Identities = 119/773 (15%), Positives = 229/773 (29%), Gaps = 137/773 (17%) Query: 120 IEYNLENSQL--SILTANIEKQPSSSHYYALPEQGSYGALFRRQLNWSQSNESDYAGRY- 176 + ++ +L +I A + + L + G L + + ++ G Sbjct: 147 AQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSV-QNRIGGNSH 205 Query: 177 ----NLQAQASIGQWTTLLEGEVTQNNEETLNST-----IQQLYTERQNEGHFYRLGYFS 227 NLQ+ +IG W + N+ ++ + + + ER RL Sbjct: 206 YAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTLGD 265 Query: 228 PYAQGLVRQPIIYSGSSQAVMGVMLGDSNQLLVD--QAYASA-TPIYVTPNRAGVVEIYQ 284 Y QG + G L + +L D + +A I + V I Q Sbjct: 266 GYTQGDI-------FDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQ---VTIKQ 315 Query: 285 NGQLINSQQINAGLQAIDTKVLPSGIYEVEIRILE-DGQVTERRREIINKPIQWQNTEEP 343 NG I + + G I+ ++++ I E DG Q P Sbjct: 316 NGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGST--------------QIFTVP 361 Query: 344 F------------RVNLFAGEKLQDITNWDD------ESRRGLSTGVLAN--YLLTPAII 383 + R ++ AGE + GL G L Sbjct: 362 YSSVPLLQREGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYR 421 Query: 384 LGAAAQFVDKGWHYSVSADWDW-----NQQLRFFGNWV------MNDQQGSDFDL----- 427 + G ++S D + G V ++ G++ L Sbjct: 422 AFNFGIGKNMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRY 481 Query: 428 ---------QAVYSYRQGSFVLS----HQQQLSQSQSSDITNSNPKKTSASLQHNLGRGH 474 YS G + + Q + + ++ + K ++ LGR Sbjct: 482 STSGYFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTS 541 Query: 475 SVSAYLSHQSEQGQG-----IDLGWQYSGKLWGRQMSWSLNAFDRPGSINTSGQRDQGGA 529 ++ SHQ+ G G + ++W+L+ + Q+ + Sbjct: 542 TLYLSGSHQTYWGTSNVDEQFQAGL---NTAFED-INWTLSYS----LTKNAWQKGRDQM 593 Query: 530 LYFSMNLGDQKRRMGGGLGSRTSRSG-GQEQHAYVDYQQQLDWRGIETIGMGL------- 581 L ++N+ Q +HA Y D G T G+ Sbjct: 594 LALNVNI---------PFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLED 644 Query: 582 NTDSYGVGA-TANSRFSNNIVSGDAYAQSSSYNSGITGGINLDSMVALGQQGKLGISGQS 640 N SY V A N+ +G A G + +Q G+SG Sbjct: 645 NNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIGYSHSDD---IKQLYYGVSGGV 701 Query: 641 QNHDAGMIIDVMADTPDIILQAEDEHGGSVTLKP-------GRNLVP-VTAYRSGSVQLA 692 H G+ + + ++++A V + G ++P T YR V L Sbjct: 702 LAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTDWRGYAVLPYATEYRENRVALD 761 Query: 693 IQDYDDTPSVIQPSVLHYHLNKGGVSYQQIRVMKTVTVIGRLVNQQGLPLKGALIANHAG 752 D + + +G + + + + ++ L + GA++ + + Sbjct: 762 TNTLADNVDLDNAVA-NVVPTRGAIVRAEFKARVGIKLLMTLTHNNKPLPFGAMVTSESS 820 Query: 753 RSLSEA--DGFFAVEMSERHPSLQVEY--QGVQECNLELDLHRVKREQNLLLV 801 +S +G + +QV++ + C L ++Q L + Sbjct: 821 QSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCVANYQLPPESQQQLLTQL 873
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 55.6 bits (134), Expect = 2e-11 Identities = 21/86 (24%), Positives = 46/86 (53%), Gaps = 6/86 (6%) Query: 2 AFKIILADDHPIILTGVRSLMAEMQPSCDIVAEANNVSELWRTLEQHECDLLITDFSMPN 61 I++ADD I T + ++ I + N + LWR + + DL++TD MP+ Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITS---NAATLWRWIAAGDGDLVVTDVVMPD 59 Query: 62 DDNVDGMAMIKQLRRKYPNLPIIVLT 87 + + ++ ++++ P+LP++V++ Sbjct: 60 E---NAFDLLPRIKKARPDLPVLVMS 82
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 62.2 bits (151), Expect = 6e-12 Identities = 25/124 (20%), Positives = 49/124 (39%), Gaps = 7/124 (5%) Query: 912 KILLIEDHQLNQILVQRQLKQLRLDCDIAEHGVQALDLMQQTHYDLILCDCRMPVMDGYT 971 IL+ +D + ++ + L + D I + + DL++ D MP + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 972 FTQQVRAQEIDGQHVPIIALTANVLNEQKQRCAAVEMD--DLLAKPLHLNELHEMLLKWL 1029 +++ +P++ ++A N A E D L KP L EL ++ + L Sbjct: 65 LLPRIKKA---RPDLPVLVMSAQ--NTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119 Query: 1030 PHSK 1033 K Sbjct: 120 AEPK 123
>PF05272#Virulence-associated E family protein Length = 892 Score = 32.4 bits (73), Expect = 0.003 Identities = 11/39 (28%), Positives = 17/39 (43%) Query: 26 CKAGEVLAVVGPSGGGKTTLLRMIAGLNHPDAGSIVFGE 64 CK + + G G GK+TL+ + GL+ G Sbjct: 593 CKFDYSVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGT 631
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 60.8 bits (147), Expect = 9e-14 Identities = 24/67 (35%), Positives = 32/67 (47%) Query: 1 MKTETQSTRQHILDIGYSLIIKQGFSCLGLAQLLKAAEVPKGSFYHYFKSKEQFGEALLT 60 K E Q TRQHILD+ L +QG S L ++ KAA V +G+ Y +FK K + Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 61 GYFEQYQ 67 Sbjct: 65 LSESNIG 71
>PF06580#Sensor histidine kinase Length = 349 Score = 38.7 bits (90), Expect = 2e-05 Identities = 35/187 (18%), Positives = 71/187 (37%), Gaps = 33/187 (17%) Query: 167 LIIEQADRLRSLVDRL-------LGPQRPTQHSLHNIHQVVQKVYKLVEIALPANIQLKR 219 LI+E + R ++ L L Q SL + VV +L I +Q + Sbjct: 185 LILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFEN 244 Query: 220 DYDPSIPDIEMDPDQMQQAVLNILQNAVQALEHTDGEILIRTRTQHQVTIGSQRHKLVLT 279 +P+I D+++ P +Q V N +++ + L G+IL++ + +T Sbjct: 245 QINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQ-GGKILLKGTKDNGT----------VT 293 Query: 280 LSIIDNGPGIPPELMDTLFYPMVTSREQGSGLGLSIAHNIARLHSG---RIDCVSSPGHT 336 L + + G + + ++ +G GL ++ G +I G Sbjct: 294 LEVENTGSL------------ALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKV 341 Query: 337 EFIISLP 343 ++ +P Sbjct: 342 NAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 559 bits (1441), Expect = 0.0 Identities = 198/474 (41%), Positives = 294/474 (62%), Gaps = 12/474 (2%) Query: 7 VWILDDDSSIRWVLEKALQGAKLSTASFAAAESLWQALEISQPRVIVSDIRMPGTDGLTL 66 + + DDD++IR VL +AL A + A +LW+ + ++V+D+ MP + L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 67 LERLQIHYPHIPVIIMTAHSDLDSAVSAYQAGAFEYLPKPFDIDEAISLVERALTHATEQ 126 L R++ P +PV++M+A + +A+ A + GA++YLPKPFD+ E I ++ RAL + Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRR 125 Query: 127 SPTPVAQETQVKTPEIIGEAPAMQEVFRAIGRLSRSSISVLINGQSGTGKELVAGALHKH 186 ++ ++G + AMQE++R + RL ++ ++++I G+SGTGKELVA ALH + Sbjct: 126 PSKL--EDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDY 183 Query: 187 SPRKDKPFIALNMAAIPKDLIESELFGHEKGAFTGAANVRQGRFEQANGGTLFLDEIGDM 246 R++ PF+A+NMAAIP+DLIESELFGHEKGAFTGA GRFEQA GGTLFLDEIGDM Sbjct: 184 GKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDM 243 Query: 247 PLDVQTRLLRVLADGQFYRVGGHSAVQVDVRIIAATHQDLEQLVLKGGFREDLFHRLNVI 306 P+D QTRLLRVL G++ VGG + ++ DVRI+AAT++DL+Q + +G FREDL++RLNV+ Sbjct: 244 PMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVV 303 Query: 307 RIHLPPLSQRREDIPQLASHFLASAAKEIGVEAKILTKETAAKLSQLPWPGNVRQLENTC 366 + LPPL R EDIP L HF+ A KE G++ K +E + PWPGNVR+LEN Sbjct: 304 PLRLPPLRDRAEDIPDLVRHFVQQAEKE-GLDVKRFDQEALELMKAHPWPGNVRELENLV 362 Query: 367 RWLTVMASGQEILPQDLPPELLKEPTSINPMAKGSQDWQSALTEWIDQKLSE-------- 418 R LT + I + + EL E ++ ++++ +++ + + Sbjct: 363 RRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDA 422 Query: 419 -GNSDLLTEVQPAFERILLETALRHTQGHKQEAAKRLGWGRNTLTRKLKELSMD 471 S L V E L+ AL T+G++ +AA LG RNTL +K++EL + Sbjct: 423 LPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 67.3 bits (164), Expect = 9e-16 Identities = 46/202 (22%), Positives = 71/202 (35%), Gaps = 25/202 (12%) Query: 1 MKKLSLVAGSLLSILVAGQALAATDTTGFYVGGAL-------NRVTVDVLDDAETGTGFG 53 MKK +A ++ A A AA +Y G L + E G G Sbjct: 1 MKKT-AIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFINNNGPTHENQLGAG 59 Query: 54 VYGGYNFNEWFGLEANLFATGDL----GDKDVDISAGALTFTPKFTLQINDMFSAYAKVG 109 +GGY N + G E G + ++ A + T K I D Y ++G Sbjct: 60 AFGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPITDDLDIYTRLG 119 Query: 110 VASMAMNVDGDGFDEDF-TGFGWTYGVGVNAAVTERLNVRLSYDVTS--GDLDADHHYVN 166 + + + ++ TG + GV A+T + RL Y T+ GD Sbjct: 120 GMVWRADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDAHTI----- 174 Query: 167 YVNVKDIDTDIKQLAIGVHYQF 188 D L++GV Y+F Sbjct: 175 -----GTRPDNGMLSLGVSYRF 191
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 94.9 bits (236), Expect = 1e-24 Identities = 45/163 (27%), Positives = 76/163 (46%), Gaps = 3/163 (1%) Query: 2 SRILLIDDDLGLSELLGQLLELEGFKLTLAYDGKQGLELALATDYDLILLDVMLPKLNGF 61 + IL+ DDD + +L Q L G+ + + + A D DL++ DV++P N F Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 EVLRALRQH-KQTPVLMLTARGDEIDRVVGLEIGADDYLPKPFNDRELIARIRAIIRRSH 120 ++L +++ PVL+++A+ + + E GA DYLPKPF+ ELI I + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 121 LTAQEIHATPAQEFGDLRLDPSRQEAYCNEQLIILTGTEFTLL 163 ++ + + QE Y L L T+ TL+ Sbjct: 124 RRPSKLEDDSQDGMPLVGRSAAMQEIY--RVLARLMQTDLTLM 164
>PF06580#Sensor histidine kinase Length = 349 Score = 38.7 bits (90), Expect = 4e-05 Identities = 25/126 (19%), Positives = 51/126 (40%), Gaps = 6/126 (4%) Query: 274 IAYEAEQLEQLIAELLELSRVKLSTNETKVCLGLAESLSQVLDDAEFEADQQGKKIT--I 331 I + + +++ L EL R L + + LA+ L+ V + + Q ++ Sbjct: 186 ILEDPTKAREMLTSLSELMRYSLRYSNARQVS-LADELTVVDSYLQLASIQFEDRLQFEN 244 Query: 332 DIDEAIELSHYPK-SLSRAIENLLRNAIRYAKSD--IHLHASQTSGQVQITIKDDGPGID 388 I+ AI P + +EN +++ I I L ++ +G V + +++ G Sbjct: 245 QINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLAL 304 Query: 389 PAELES 394 ES Sbjct: 305 KNTKES 310
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 336 bits (863), Expect = e-111 Identities = 119/375 (31%), Positives = 197/375 (52%), Gaps = 20/375 (5%) Query: 259 FHRDLALHLHTQALGVTQTKSAKTIQDKPQSQLGVRFRDPLLERAWQQANKVITKQIPLL 318 F + + +AL + ++D Q + + R ++ ++ +++ + L+ Sbjct: 106 FDLTELIGIIGRALA-EPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLM 164 Query: 319 VLGETGVGKEQFVKKLHAQSSRRAQPLVAVNCAALPAELVESELFGYQAGAFTGANRSGF 378 + GE+G GKE + LH RR P VA+N AA+P +L+ESELFG++ GAFTGA Sbjct: 165 ITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRS- 223 Query: 379 IGKIRQAHGGFLFLDEIGEMPQAAQSRLLRVLQEREVVPVGSNQSVKVDIQIIAATHMDL 438 G+ QA GG LFLDEIG+MP AQ+RLLRVLQ+ E VG ++ D++I+AAT+ DL Sbjct: 224 TGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDL 283 Query: 439 ESLVAQGLFRQDLFYRLNGLQVRLPALRERQ-DIERIIH---KLHRRHRSGPQTLCTELL 494 + + QGLFR+DL+YRLN + +RLP LR+R DI ++ + + + E L Sbjct: 284 KQSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEAL 343 Query: 495 GQLMRYDWPGNLRELDNLMQVACLMAEDDEVLARAHLPEHLAKKLVNKPLAVYERQHVEN 554 + + WPGN+REL+NL++ + D V+ R + L ++ + P+ + Sbjct: 344 ELMKAHPWPGNVRELENLVRRLTALYPQD-VITREIIENELRSEIPDSPIEKAAARSGSL 402 Query: 555 PQNPRDKDDIGRHSADSLHGAINQNVL-------------QAYRACEGNVSQCAKRLGIS 601 + ++++ ++ A + A A GN + A LG++ Sbjct: 403 SISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLN 462 Query: 602 RNALYRKLKQLGIKD 616 RN L +K+++LG+ Sbjct: 463 RNTLRKKIRELGVSV 477
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 565 bits (1457), Expect = 0.0 Identities = 233/333 (69%), Positives = 268/333 (80%), Gaps = 1/333 (0%) Query: 1 MKYLVTGAAGFIGANVSKRLCAMGHEVVGIDNLNDYYDVALKLARLAPLEALSNFHFIKL 60 MKYLVTGAAGFIG +VSKRL GH+VVGIDNLNDYYDV+LK ARL L F F K+ Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQ-PGFQFHKI 59 Query: 61 DLADREGIAKLFAQQGFQRVIHLAAQAGVRYSLDNPLAYADSNLVGHLTILEGCRHHKIE 120 DLADREG+ LFA F+RV + VRYSL+NP AYADSNL G L ILEGCRH+KI+ Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ 119 Query: 121 HLVYASSSSVYGLNQKMPFSTEDSVDHPISLYAATKKANELMSHTYSHLYQLPTTGLRFF 180 HL+YASSSSVYGLN+KMPFST+DSVDHP+SLYAATKKANELM+HTYSHLY LP TGLRFF Sbjct: 120 HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFF 179 Query: 181 TVYGPWGRPDMALFKFTKAILAGETIDVYNHGDLSRDFTYIDDIVEGIIRVQDKPPSPTP 240 TVYGPWGRPDMALFKFTKA+L G++IDVYN+G + RDFTYIDDI E IIR+QD P Sbjct: 180 TVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHADT 239 Query: 241 DWRVETGTPANSSAPYRVFNIGNGSPVQLLDFITALERALGIEAKKQFLPMQPGDVHATW 300 W VETGTPA S APYRV+NIGN SPV+L+D+I ALE ALGIEAKK LP+QPGDV T Sbjct: 240 QWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQPGDVLETS 299 Query: 301 ADTEDLFKAVGYKSQVDIDTGVAKFVDWYRNFY 333 ADT+ L++ +G+ + + GV FV+WYR+FY Sbjct: 300 ADTKALYEVIGFTPETTVKDGVKNFVNWYRDFY 332
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1255 bits (3250), Expect = 0.0 Identities = 657/1032 (63%), Positives = 808/1032 (78%), Gaps = 4/1032 (0%) Query: 1 MARFFIDRPIFAWVIALIIMLAGVLSIRTLPVSQYPSIAPPTVVISANYPGASAKIVEDS 60 MA FFI RPIFAWV+A+I+M+AG L+I LPV+QYP+IAPP V +SANYPGA A+ V+D+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQVIEQRMKGIDHLRYIASTSDSFGNAEITLTFNAEADPDIAQVQVQNKLQGAMTLLPQ 120 VTQVIEQ M GID+L Y++STSDS G+ ITLTF + DPDIAQVQVQNKLQ A LLPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVQAQGVDVNKSSSGFLMVLGFVSTDGSLDKGDIADYVGANVQDPMSRVPGVGEIQLFGA 180 EVQ QG+ V KSSS +LMV GFVS + + DI+DYV +NV+D +SR+ GVG++QLFGA Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QYAMRIWLDPLKLTQYNLTSLEVISAIRAQNAQVSAGQLGGTPSIQGQELNATVSAQSRL 240 QYAMRIWLD L +Y LT ++VI+ ++ QN Q++AGQLGGTP++ GQ+LNA++ AQ+R Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 QTPEEFRKIILKSDTSGANVFLGDVARVELGSESYAVVSFYNGKPATGLAIKLATGANAL 300 + PEEF K+ L+ ++ G+ V L DVARVELG E+Y V++ NGKPA GL IKLATGANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 DTAEAVRDKVEELRPFFPQGLDVVYPYDTTPFVEKSIEGVVHTLLEAIVLVFVIMYLFLQ 360 DTA+A++ K+ EL+PFFPQG+ V+YPYDTTPFV+ SI VV TL EAI+LVF++MYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NFRATLIPTIAVPVVLLGTFAILSATGFSINTLTMFAMVLAIGLLVDDAIVVVENVERVM 420 N RATLIPTIAVPVVLLGTFAIL+A G+SINTLTMF MVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 SEEGLSPLEATRKSMDQITGALVGIGLTLSAVFVPMAFMSGSTGVIYRQFSITIVSAMAL 480 E+ L P EAT KSM QI GALVGI + LSAVF+PMAF GSTG IYRQFSITIVSAMAL Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLVALILTPALCATMLKPVQKGHGHIETGFFGWFNRNFDRLTNRYESSVAGIVKRGFRV 540 SVLVALILTPALCAT+LKPV H + GFFGWFN FD N Y +SV I+ R Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 Query: 541 MMIYVALVVAVGWIFMRMPTAFLPDEDQGILFTQAILPTNSTQESTLKVLDKVSDHFMA- 599 ++IY +V + +F+R+P++FLP+EDQG+ T LP +TQE T KVLD+V+D+++ Sbjct: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 Query: 600 -EEGVRSVFSVAGFSFAGQGQNMGIAFVGLKDWSEREAPGMDVQSIAGRAMGAFSQIKDA 658 + V SVF+V GFSF+GQ QN G+AFV LK W ER +++ RA +I+D Sbjct: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG 660 Query: 659 FVFAFVPPAVIELGTANGFDMYLQDKNGQGHDKLIAARNQLLGMAAQNP-NLMGVRPNGQ 717 FV F PA++ELGTA GFD L D+ G GHD L ARNQLLGMAAQ+P +L+ VRPNG Sbjct: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 Query: 718 EDAPIYQLHIDHAKLSALGVDIANVNSVLATAWGGSYVNDFIDRGRVKKVFVQGDAQYRM 777 ED ++L +D K ALGV ++++N ++TA GG+YVNDFIDRGRVKK++VQ DA++RM Sbjct: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM 780 Query: 778 QPEDLNTWYVRNNKGDMVPFSAFATGSWEYGSPRLERFNGLPAVNIQGATAPGFSTGAAM 837 PED++ YVR+ G+MVPFSAF T W YGSPRLER+NGLP++ IQG APG S+G AM Sbjct: 781 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM 840 Query: 838 TIMEDLVKQLPPGFGIEWNGLSYEERLSGNQAPALYALSILVVFLVLAALYESWSVPFAV 897 +ME+L +LP G G +W G+SY+ERLSGNQAPAL A+S +VVFL LAALYESWS+P +V Sbjct: 841 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900 Query: 898 ILVVPLGIIGALLAMNGRGLPNDVFFQVGLLTTVGLATKNAILIVEFAKEFYEK-GAGLV 956 +LVVPLGI+G LLA NDV+F VGLLTT+GL+ KNAILIVEFAK+ EK G G+V Sbjct: 901 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV 960 Query: 957 EATLHAVRVRLRPILMTSLAFGLGVVPLAISTGVGSGSQNAIGTGVLGGMMSSTFLGIFF 1016 EATL AVR+RLRPILMTSLAF LGV+PLAIS G GSG+QNA+G GV+GGM+S+T L IFF Sbjct: 961 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF 1020 Query: 1017 VPLFFVIVERIF 1028 VP+FFV++ R F Sbjct: 1021 VPVFFVVIRRCF 1032 Score = 85.3 bits (211), Expect = 8e-19 Identities = 76/527 (14%), Positives = 164/527 (31%), Gaps = 44/527 (8%) Query: 534 VKRGFRVMMIYVALVVAVGWIFMRMPTAFLPDEDQGILFTQAILPTNSTQESTLKVLDKV 593 ++R ++ + L++A +++P A P + A P Q V + Sbjct: 6 IRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQVI 65 Query: 594 SDHFMAEEGVRSVFSVAGFSFAGQGQNMGIAFVGLKDWSEREAPGMDVQSIAGRAMGAFS 653 + + + + S S + + + F G D + Sbjct: 66 EQNMNGIDNLMYMSST---SDSAGSVTITLTF----------QSGTDPDIAQVQVQNKLQ 112 Query: 654 QIKDAFVFAFVPPAVIELGTANGFDMYL----QDKNGQGHDKLIAARNQLLGMAAQNPNL 709 + +++ + M + D + + ++ + Sbjct: 113 LATPLLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGV 172 Query: 710 MGVRPNGQEDAPIYQLHI--DHAKLSALGVDIANVNSVLATA----WGGSYVNDFIDRGR 763 V+ G + Y + I D L+ + +V + L G G+ Sbjct: 173 GDVQLFGAQ----YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQ 228 Query: 764 VKKVFVQGDAQYRMQPEDLNTWYVRNNK-GDMVPFSAFAT---GSWEYGSPRLERFNGLP 819 + +++ PE+ +R N G +V A G Y + R NG P Sbjct: 229 QLNASIIAQTRFK-NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNV--IARINGKP 285 Query: 820 AVNIQGATAPGFST----GAAMTIMEDLVKQLPPGFGIEW---NGLSYEERLSGNQAPAL 872 A + A G + A + +L P G + + + + Sbjct: 286 AAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLF 345 Query: 873 YALSILVVFLVLAALYESWSVPFAVILVVPLGIIGALLAMNGRGLPNDVFFQVGLLTTVG 932 A I++VFLV+ ++ + VP+ ++G + G + G++ +G Sbjct: 346 EA--IMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIG 403 Query: 933 LATKNAILIVE-FAKEFYEKGAGLVEATLHAVRVRLRPILMTSLAFGLGVVPLAISTGVG 991 L +AI++VE + E EAT ++ ++ ++ +P+A G Sbjct: 404 LLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGST 463 Query: 992 SGSQNAIGTGVLGGMMSSTFLGIFFVPLFFVIVERIFSKRERKAKEK 1038 ++ M S + + P + + S + K Sbjct: 464 GAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGG 510
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 40.2 bits (94), Expect = 9e-06 Identities = 38/211 (18%), Positives = 80/211 (37%), Gaps = 32/211 (15%) Query: 99 TYKAALVSANADLARANASLASAKAKAARYQQLVKTNAISKQDFD-EADAAYKEALASVT 157 + V A +L + L +++ ++ + Q F E ++ ++ Sbjct: 256 EQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLV---TQLFKNEILDKLRQTTDNIG 312 Query: 158 VAEAAINTAKINLEYTEVLAPISGRIGKSSV-TAGALVTANQSQTLATIQQLDPINVDIA 216 + + + + + + AP+S ++ + V T G +VT ++TL + I Sbjct: 313 LLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTT--AETL----------MVIV 360 Query: 217 QSSAQLLRLKAKLKQ---GKLLAADNADVQLVLVDGTVYGH-TGKLQ--FAEVSVDQNTG 270 L + A ++ G + NA +++ T YG+ GK++ + DQ G Sbjct: 361 PEDDTLE-VTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLG 419 Query: 271 SV--ILRA------EFPNPDGVLLPGMYVRA 293 V ++ + N + L GM V A Sbjct: 420 LVFNVIISIEENCLSTGNKNIPLSSGMAVTA 450 Score = 37.9 bits (88), Expect = 5e-05 Identities = 36/174 (20%), Positives = 66/174 (37%), Gaps = 45/174 (25%) Query: 57 GRSKAFLEAEVRPQVNGIITKRSFV-EGGNVKQGESLYQIDSATYKAALVSANADLARAN 115 GRSK E++P N I+ K V EG +V++G+ L ++ + + A AD + Sbjct: 94 GRSK-----EIKPIENSIV-KEIIVKEGESVRKGDVLLKLTA-------LGAEADTLKTQ 140 Query: 116 ASLASAKAKAARYQQLVKTNAISKQDFDEADAAYKEALASVTVAEAAINTAKINLEYTEV 175 +SL A+ + RYQ L + +I E + +V+ E T+ I Sbjct: 141 SSLLQARLEQTRYQILSR--SIELNKLPELKLPDEPYFQNVSEEEVLRLTSLI------- 191 Query: 176 LAPISGRIGKSSVTAGALVTANQSQTLATIQQLDPINVDIAQSSAQLLRLKAKL 229 + Q Q +++ + A+ L + A++ Sbjct: 192 ----------------------KEQFSTWQNQKYQKELNLDKKRAERLTVLARI 223
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 27.8 bits (62), Expect = 0.038 Identities = 20/93 (21%), Positives = 32/93 (34%), Gaps = 7/93 (7%) Query: 97 FIGKAGEFG--DSGFTYDVMLFSYLYPGASYSNYTELWLKVGKQFGRANLQLEITPTVDD 154 FIG G FG G V+ + + +L V K + + + Sbjct: 97 FIGLKGGFGKLRVGRLNSVL---KDTGDINPWDSKSDYLGVNKIAEPEARLISVRYDSPE 153 Query: 155 WFGVDGWHGVNYALHPSYSFDNGVKISASVGYQ 187 + G+ G V YAL+ + N A Y+ Sbjct: 154 FAGLSG--SVQYALNDNAGRHNSESYHAGFNYK 184