>PF01206#SirA family protein Length = 76 Score = 91.4 bits (227), Expect = 2e-28 Identities = 17/71 (23%), Positives = 38/71 (53%) Query: 10 DYRLDMVGEPCPYPAVATLEAMPSLKKGEILEVVSDCPQSINNIPLDAKNYGYTVLDIQQ 69 D LD G CP P + + + ++ GE+L V++ P S+ + +K G+ +L+ ++ Sbjct: 5 DQSLDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKE 64 Query: 70 DGPTIRYLIQK 80 + T + +++ Sbjct: 65 EDGTYHFRLKR 75
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 52.6 bits (126), Expect = 1e-09 Identities = 31/126 (24%), Positives = 56/126 (44%), Gaps = 14/126 (11%) Query: 6 MKSLKPLAALVGLLVLSGSANAVNVYNDKGTRFDVNGQFRLKTQVTSKDHEMRMRDDG-- 63 MK K LA ++ L+ +G+A+A +YN G + D+ G+ + DG Sbjct: 1 MK-RKVLALVIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSDDS-----SKDGDQ 54 Query: 64 --SRIGFFGSHELTNDIKVFGKLEWGSDTQKTNSDNEKTNFDLYNRVGYVGFSHRDYGQI 121 R+GF G ++ + + +G+ E+ T + + + R+ + G DYG Sbjct: 55 TYMRVGFKGETQINDQLTGYGQWEYNVQANTTEGEGANS----WTRLAFAGLKFGDYGSF 110 Query: 122 QFGRTY 127 +GR Y Sbjct: 111 DYGRNY 116
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 44.8 bits (106), Expect = 2e-06 Identities = 39/226 (17%), Positives = 84/226 (37%), Gaps = 27/226 (11%) Query: 754 LDYLQKTIKTYQQQSEHLHQQQQQL-AQHIQSAIEKQGYTLPEFEQFTPWLAARQQEHQQ 812 L L T + QS L + +Q Q + +IE + + ++E + Sbjct: 127 LTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLR 186 Query: 813 YQSQLKELQLLQQSLREQQVTQNEKKRYLAEKQAELEALLAKLSQQQHQQTQWQDQR--- 869 S +KE Q S + Q Q E L +K+AE +LA++++ ++ + + Sbjct: 187 LTSLIKE----QFSTWQNQKYQKELN--LDKKRAERLTVLARINRYENLSRVEKSRLDDF 240 Query: 870 QALFGSQSVEQVRSELDKHSQFLQTQIEQYTQEKNQLENRLNQLIGQYQENEKALQRAIT 929 +L Q++ + + + + + N L Q ++ E + A Sbjct: 241 SSLLHKQAIAKHA-------------VLEQENKYVEAVNELRVYKSQLEQIESEILSAKE 287 Query: 930 QAQQATEHYQHALKESLFADENDFLASLLSVEERTRLQEQQKQRLD 975 + Q T+ +++ + + L D + L E+++Q Sbjct: 288 EYQLVTQLFKNEILDKL-RQTTDNIGLL---TLELAKNEERQQASV 329 Score = 32.5 bits (74), Expect = 0.013 Identities = 16/145 (11%), Positives = 45/145 (31%), Gaps = 11/145 (7%) Query: 203 ALNTLKQQAQMMALLDATTRQELLTQQANIQTQITRLQKEQQEYQVAKQWQEKALEIQQQ 262 N +++ + L Q+ + + + + E+ E +++ Sbjct: 176 FQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKS 235 Query: 263 QQSAQAGLY-----------EAQQALIIAQPDIQRLEKNEPAEKIRPLYDEKNRRLTEQN 311 + + L E + + A +++ + + L ++ +L Q Sbjct: 236 RLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQL 295 Query: 312 YLATQLTSLKTEKQAIEQQSLPINK 336 + L L+ I +L + K Sbjct: 296 FKNEILDKLRQTTDNIGLLTLELAK 320
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 91.0 bits (226), Expect = 2e-23 Identities = 31/121 (25%), Positives = 60/121 (49%), Gaps = 2/121 (1%) Query: 4 RILVVEDETAIREMICFVLEQNGFQPIEAEDYDTALSFLIDPYPDLVLLDWMIPGGSGIQ 63 ILV +D+ AIR ++ L + G+ + T ++ DLV+ D ++P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 64 VIKQMKRENNTRDIPIIMLTAKGEEEDKVKGLETGADDYVIKPFSPKELVARVKAILRRL 123 ++ ++K+ D+P+++++A+ +K E GA DY+ KPF EL+ + L Sbjct: 65 LLPRIKKARP--DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 124 S 124 Sbjct: 123 K 123
>PF06580#Sensor histidine kinase Length = 349 Score = 30.6 bits (69), Expect = 0.013 Identities = 20/102 (19%), Positives = 33/102 (32%), Gaps = 21/102 (20%) Query: 322 VSNLVYNAINHTPEGTTIRVSWKKVPQGMLFSVSDNGPGISAEHLTRLTERFYRVDKARS 381 V N + + I P+G I + K + V + G A Sbjct: 264 VENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSL------------------ALK 305 Query: 382 RHTGGTGLGLAIVKKSLQHHH---SILNIESKVGVGSTFSFI 420 TG GL V++ LQ + + + + K G + I Sbjct: 306 NTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLI 347
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 75.2 bits (185), Expect = 8e-17 Identities = 66/355 (18%), Positives = 128/355 (36%), Gaps = 22/355 (6%) Query: 23 LRMLGMFMVLPVLTTYGLQLQHATE--SLIGLAIGIYGLTQAIFQIPFGFFSDKFGRKSM 80 L +G+ +++PVL L H+ + + G+ + +Y L Q G SD+FGR+ + Sbjct: 16 LDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPV 75 Query: 81 IVFGLIIFIVGSLTAALSDSIYGIIIGRALQG-AGAISAAVMALLSDLTREQNRTKAMAF 139 ++ L V A + ++ + IGR + G GA A A ++D+T R + F Sbjct: 76 LLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGF 135 Query: 140 IGISFGITFALALVLGPILTHIFGLQGLFWGIALLAFGGIMITLITVPNSEHHILNRESS 199 + FG VLG ++ F+ A L + +P S Sbjct: 136 MSACFGFGMVAGPVLGGLMGGF-SPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRR 194 Query: 200 FVRGSVKKVLFDAQLLKLNVGIFSLHTLLMAAFVA-----LPLIMHNAGLVNEKHWVVYL 254 + + G+ + L+ F+ +P + + HW Sbjct: 195 EALNPLAS-------FRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATT 247 Query: 255 VTMLIAFISVLPFIIYAEKKRKMKQVF--LLCIFLLIIAQA---IFMISGTSLWLIILGI 309 + + +A +L + A + + L +IA I + T W+ + Sbjct: 248 IGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIM 307 Query: 310 QIFFIGFNIMEALLPSLISKEAPAGYKGTAMGIYSTSQFLGVALGGILGGWLYQH 364 + I L +++S++ +G G + L +G +L +Y Sbjct: 308 -VLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAA 361
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 32.5 bits (74), Expect = 0.003 Identities = 66/314 (21%), Positives = 119/314 (37%), Gaps = 20/314 (6%) Query: 62 KFLWSPFMDRYTPSFLGRRRGWMLLTQIGLVLGIAGMGFLNPSHHLWWLASLAVIVAFCS 121 +F +P + + F RR +L++ G + A M W+ + IVA + Sbjct: 56 QFACAPVLGALSDRF--GRRPVLLVSLAGAAVDYAIMAT----APFLWVLYIGRIVAGIT 109 Query: 122 ASQDIVFDAYKTDILKADERGTGAAVSVLGYRIAMLVSGGMALWLADKYIGWQNMYWLMA 181 + V AY DI DER + M+ + + ++ A Sbjct: 110 GATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG--FSPHAPFFAAA 167 Query: 182 ALMGIGIIATLLAQEPETAVKPPRTLYEAVIEPL----YEFFSRNNAWLILLLIVLYKMG 237 AL G+ + PE+ R L + PL + A L+ + ++ +G Sbjct: 168 ALNGLNFLTGCFLL-PESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVG 226 Query: 238 DAFALSLSTTFLIRGAGFDAGEVGLVNKTLGLAATIVGALLGGLLMRRWTLFKALMIFGI 297 A +L F +DA +G+ G+ ++ A++ G + R +ALM+ I Sbjct: 227 QVPA-ALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMI 285 Query: 298 LQGGSNIGYWYLAISEQNIYSMGAVIAFENICGGMGTAAFVALLMTLCHQSFSATQFALL 357 G GY LA + + + ++ GG+G A A+L + L Sbjct: 286 ADG---TGYILLAFATRGWMAFPIMVLL--ASGGIGMPALQAMLSRQVDEERQGQLQGSL 340 Query: 358 SALAAIGRVYVGPV 371 +AL ++ + VGP+ Sbjct: 341 AALTSLTSI-VGPL 353
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 28.6 bits (64), Expect = 0.046 Identities = 12/73 (16%), Positives = 25/73 (34%), Gaps = 13/73 (17%) Query: 60 ERSELPTPHEIRKHLDDYVIGQELAKKVLAVAVYNHYKRLRNGDKADGVELGKSNILLIG 119 E P+ E ++G+ A + + + +++ G Sbjct: 121 EPKRRPSKLEDDSQDGMPLVGRSAA-----------MQEIY--RVLARLMQTDLTLMITG 167 Query: 120 PTGSGKTLLAETL 132 +G+GK L+A L Sbjct: 168 ESGTGKELVARAL 180
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 39.3 bits (91), Expect = 5e-05 Identities = 23/120 (19%), Positives = 48/120 (40%), Gaps = 5/120 (4%) Query: 160 EESAKLADTIASHMPLKLKDKQAVLEMSDVTERLEYLMAMMESEIDLLQVEKRIRNRVKK 219 +A+ AD + ++ + L A L+ Sbjct: 222 ALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSA 281 Query: 220 QMEKSQREYYLNEQMKAIQKELGEMDDAPDEMESLKRKIEAAKMPKEAREKTEAELQKLK 279 +++ + E E KA + ++ +A +SL+R ++A++ EA+++ EAE QKL+ Sbjct: 282 KIKTLEAEKAALEAEKADLEHQSQVLNA--NRQSLRRDLDASR---EAKKQLEAEHQKLE 336 Score = 34.7 bits (79), Expect = 0.002 Identities = 27/121 (22%), Positives = 57/121 (47%), Gaps = 10/121 (8%) Query: 160 EESAKLADTIASHMPLKLKDKQAVLEMSDVTERLEYLMAMMESEIDLLQVEKRIRNRVKK 219 A+L + M D + + LE A +E + +L R +++ Sbjct: 260 ARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNAN---RQSLRR 316 Query: 220 QMEKSQREYYLNEQMKAIQKELGEMDDAPD-EMESLKRKIEAAKMPKEAREKTEAELQKL 278 ++ S+ +Q++A ++L E + + +SL+R ++A++ EA+++ EAE QKL Sbjct: 317 DLDASREAK---KQLEAEHQKLEEQNKISEASRQSLRRDLDASR---EAKKQLEAEHQKL 370 Query: 279 K 279 + Sbjct: 371 E 371
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 121 bits (306), Expect = 5e-40 Identities = 50/88 (56%), Positives = 66/88 (75%) Query: 2 NKTQLIDKIAANADITKAAAGRVVDAMVASITESLQKGDDVALVGFGTFTVRDRAARTGR 61 NK LI K+A ++TK + VDA+ ++++ L KG+ V L+GFG F VR+RAAR GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 62 NPQTGKEIQIAAAKVPAFRAGKGLKDAV 89 NPQTG+EI+I A+KVPAF+AGK LKDAV Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAV 90
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1276 bits (3304), Expect = 0.0 Identities = 754/1035 (72%), Positives = 879/1035 (84%), Gaps = 3/1035 (0%) Query: 1 MPKFFIDRPIFAWVIAIITMLAGLLALIKLPVAQYPTIAPPAISISAVYPGADATTVQNT 60 M FFI RPIFAWV+AII M+AG LA+++LPVAQYPTIAPPA+S+SA YPGADA TVQ+T Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQVIEQNMNGIDNMVYMSSTSDSAGMMNITLTFEAGTDPDIAQVQVQNKLQLAMPLLPQ 120 VTQVIEQNMNGIDN++YMSSTSDSAG + ITLTF++GTDPDIAQVQVQNKLQLA PLLPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVQQQGISVDKSSSSFLMVAGFISGDGSMSQDDIADYVGATIKDPLSRVTGVGETQLFGT 180 EVQQQGISV+KSSSS+LMVAGF+S + +QDDI+DYV + +KD LSR+ GVG+ QLFG Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QYAMRIWLDPDKLVKYNMTTLDVINAIKSQNNQVAAGQLGGTPPVPGQRLNVSIIAQTRL 240 QYAMRIWLD D L KY +T +DVIN +K QN+Q+AAGQLGGTP +PGQ+LN SIIAQTR Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 NTPEQFADILMKVNQDGSQVKLKDLGIVEMGAENYSTIARFNGLPAAGIGIKLATGANAL 300 PE+F + ++VN DGS V+LKD+ VE+G ENY+ IAR NG PAAG+GIKLATGANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 DTATAVRAALADMEPFFPSGLEVVYPYDTTPFVKISIFEVVKTLVEAIMLVFVVMYLFLQ 360 DTA A++A LA+++PFFP G++V+YPYDTTPFV++SI EVVKTL EAIMLVF+VMYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NFRATLIPTIAVPVVLLGTFAILSAFGYSINTLTMFAMVLAIGLLVDDAIVVVENVERVM 420 N RATLIPTIAVPVVLLGTFAIL+AFGYSINTLTMF MVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 QEEGLSPKEATRKSMGQIQGALVGIALVLSAVFIPMAFFGGSTGAIYRQFSVTIVSAMVL 480 E+ L PKEAT KSM QIQGALVGIA+VLSAVFIPMAFFGGSTGAIYRQFS+TIVSAM L Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVFVALILTPALCATLLKPIPKGSHGVQTGFFGWFNRVFEKSSHHYTDSVSRTLRGTGRY 540 SV VALILTPALCATLLKP+ H + GFFGWFN F+ S +HYT+SV + L TGRY Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 Query: 541 LLIYVLLVAAMAIMFVRLPASFLPEEDQGVLLTMVQLPAGSTQEQTQDVLAQVNDYFNTK 600 LLIY L+VA M ++F+RLP+SFLPEEDQGV LTM+QLPAG+TQE+TQ VL QV DY+ Sbjct: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 Query: 601 EKDVVKSVFTVSGFGFGGQGQNMGLAFVVLNDWDERKSDQDKVPAIVGRANQALSQIKEA 660 EK V+SVFTV+GF F GQ QN G+AFV L W+ER D++ A++ RA L +I++ Sbjct: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG 660 Query: 661 FVYSFNIPAIVELGSAGGFEFELIDNANLGHEKLMEARNQLLGMAAQEPQMLTGVRPNGQ 720 FV FN+PAIVELG+A GF+FELID A LGH+ L +ARNQLLGMAAQ P L VRPNG Sbjct: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 Query: 721 EDTSQYRLYIDLEKAQAQGVAVSDIYSTLGTMFGGSYVNDFIDRGRVKKVYVQAESQFRM 780 EDT+Q++L +D EKAQA GV++SDI T+ T GG+YVNDFIDRGRVKK+YVQA+++FRM Sbjct: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM 780 Query: 781 LPQDIANLYVRNNAGQMVPFSSFIDTSKDPWLYGSPRLERYNGLPAVQIQGSATPGQSSG 840 LP+D+ LYVR+ G+MVPFS+F + W+YGSPRLERYNGLP+++IQG A PG SSG Sbjct: 781 LPEDVDKLYVRSANGEMVPFSAFTTSH---WVYGSPRLERYNGLPSMEIQGEAAPGTSSG 837 Query: 841 DAMLMMEQLASKLPSGIGYEWTGMSYQERLSGNQAPALYTISLIVVFLCLAALYESWSVP 900 DAM +ME LASKLP+GIGY+WTGMSYQERLSGNQAPAL IS +VVFLCLAALYESWS+P Sbjct: 838 DAMALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIP 897 Query: 901 FSVMLVVPLGVIGALAFTTLRGLENDVYFKVGLLTTIGLSAKNAILIVEFAKDLMEKEGK 960 SVMLVVPLG++G L TL +NDVYF VGLLTTIGLSAKNAILIVEFAKDLMEKEGK Sbjct: 898 VSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGK 957 Query: 961 GLVEATLDSVRMRLRPILMTSLAFMLGVIPLVLSNGAGSGAQNSVGTGVFGGMIAATSLA 1020 G+VEATL +VRMRLRPILMTSLAF+LGV+PL +SNGAGSGAQN+VG GV GGM++AT LA Sbjct: 958 GVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLA 1017 Query: 1021 IYFVPIFFVVIRRRF 1035 I+FVP+FFVVIRR F Sbjct: 1018 IFFVPVFFVVIRRCF 1032
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 43.7 bits (103), Expect = 9e-07 Identities = 34/215 (15%), Positives = 65/215 (30%), Gaps = 39/215 (18%) Query: 102 QATLNSAQADLAKAKANAEIARLTVERYKPLLGTNYVSKQDFDTAT-SQYAQAVAAVKAA 160 + A +L K+ E + K Q F + Q + Sbjct: 258 ENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLV---TQLFKNEILDKLRQTTDNIGLL 314 Query: 161 EATVTNAKINLEYTKVTAPISGR-SGKSTVTEGALVAPGQQVALTTVQQIDPIYVDVTQS 219 + + + + + AP+S + TEG +V + + + V + D + V Sbjct: 315 TLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETL-MVIVPEDDTLEVTALVQ 373 Query: 220 SEDYLKLKNEIESGIVRQEQGKPV-VHLTLTNGQSYAQKGHLE------FSDVTVDESTG 272 ++D I G+ + + Y G+L D D+ G Sbjct: 374 NKD-----------IGFINVGQNAIIKVEAFPYTRY---GYLVGKVKNINLDAIEDQRLG 419 Query: 273 SIT--MRAIV------PNPNGELLPGM----FVRT 295 + + +I N N L GM ++T Sbjct: 420 LVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKT 454 Score = 36.7 bits (85), Expect = 1e-04 Identities = 35/214 (16%), Positives = 69/214 (32%), Gaps = 28/214 (13%) Query: 49 PLTITTDLPGR-TSAYRIAEVRPQVGGIILKRNYTEGSYVEAGTSLYQIDPAIFQATLNS 107 + I G+ T + R E++P I+ + EG V G L ++ +A Sbjct: 79 QVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLK 138 Query: 108 AQADLAKAKANA----------EIARLTVERYKPLLGTNYVSKQDFDTATSQYAQAVAAV 157 Q+ L +A+ E+ +L + VS+++ TS + + Sbjct: 139 TQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTW 198 Query: 158 KAAEATVTNAKINLEYTKVTAPISGRSGKSTVTEGALVAPGQQ------------VALTT 205 + + + L K A + E + +A Sbjct: 199 QNQK-----YQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHA 253 Query: 206 VQQIDPIYVDVTQSSEDYLKLKNEIESGIVRQEQ 239 V + + YV+ Y +IES I+ ++ Sbjct: 254 VLEQENKYVEAVNELRVYKSQLEQIESEILSAKE 287
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 159 bits (404), Expect = 2e-51 Identities = 119/202 (58%), Positives = 154/202 (76%) Query: 1 MARKTKRQAQETRQQIIDAALRLFTVQGVSATSLSDIATEAGVTRGAIYWHFKNKVDLFT 60 MARKTK++AQETRQ I+D ALRLF+ QGVS+TSL +IA AGVTRGAIYWHFK+K DLF+ Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 EACELTDLKIESLELEYQSKYPDDPLFVLRELLIYILTSIVEDPKHNALLEIYFHKCEFV 120 E EL++ I LELEYQ+K+P DPL VLRE+LI++L S V + + L+EI FHKCEFV Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 121 GEMTPIVEIRRELCAADYSRIEQSLSRCIEKKQLPANLDLRRAAIMLRAMMTGLAENWLF 180 GEM + + +R LC Y RIEQ+L CIE K LPA+L RRAAI++R ++GL ENWLF Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180 Query: 181 SPESFSIKEESQYLVDSFIDMI 202 +P+SF +K+E++ V ++M Sbjct: 181 APQSFDLKKEARDYVAILLEMY 202
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 48.5 bits (115), Expect = 1e-07 Identities = 40/289 (13%), Positives = 91/289 (31%), Gaps = 29/289 (10%) Query: 20 VSILFVLLGNILFTPAKAETVSNNLPTKESIQNQLNLLNKRSDLSAEDKLTIGDLEQALL 79 V++ +LG L + + T+ + + E+ + Sbjct: 22 VAVALTVLGAGL---VVNTNEVSAVATRSQTDTLEKVQERADKFEIENNTL---KLKNSD 75 Query: 80 LLDNIQQLEKKADDYNKTVEQLPEKLRSIQNQLSQLKQKI------------ANKEVDDY 127 L N + L+ D+ + + EKLR LS+ KI A + ++ Sbjct: 76 LSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNF 135 Query: 128 RQSLESLPLATLESQLEEVLQSLAKAQEDLANYSNELIVLQTQPERAQSVLFNNSERLQQ 187 + + + TLE++ + A ++ L N + + ++ R + Sbjct: 136 STADSAK-IKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAE 194 Query: 188 IRIALNKSSADKAQMRSSSVQLLQLEQYYLQQQNSFQKRTLQSNVQLQSLLQLQRDYSSA 247 + AL + + L + ++ +K + + + + Sbjct: 195 LEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAE 254 Query: 248 YIDLSQEHAQLLQEILSDKRLD----------SSEEVAKEAQTAELSNQ 286 L A+L + + +E+ A EA+ A+L +Q Sbjct: 255 KAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQ 303
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 47.0 bits (111), Expect = 3e-07 Identities = 48/258 (18%), Positives = 86/258 (33%), Gaps = 19/258 (7%) Query: 393 PQVRSNMATATPKVSPSPENSAALGNSPAAQLLRARQAIRGAEQETPPKKPQPATP-KQA 451 P+V T +P N A + P+ + E P P PATP + Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQA--DVPSVP---SNNEEIARVDEAPVPPPAPATPSETT 1037 Query: 452 KPAASALERLAAVSEKRQQRVNEKRSSVAVEKKKKEAYQWKPQNPQA-----QVTEPVVS 506 + A ++ + EK +Q E + + KEA N Q +E + Sbjct: 1038 ETVAENSKQESKTVEKNEQDATETTAQ--NREVAKEAKSNVKANTQTNEVAQSGSETKET 1095 Query: 507 SPKEIKEVLEYEKTPELAAKIAQESQQRDEWAAEIAKMPLPKLVQQLALNAYKETVGEET 566 E KE EK E AK+ E Q ++ PK Q + E E Sbjct: 1096 QTTETKETATVEK--EEKAKVETEKTQE---VPKVTSQVSPKQEQSETVQPQAEPAREND 1150 Query: 567 IILHLRSKQKHLNSANALRTLTNALSELHGKAISL-TIIEDDNLTVKTPLEWRQAIYEEK 625 ++++ Q N+ S + ++ T + N V+ P A + Sbjct: 1151 PTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPT 1210 Query: 626 LALARQSITTDKTIQTLQ 643 + + ++ ++++ Sbjct: 1211 VNSESSNKPKNRHRRSVR 1228
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 51.6 bits (123), Expect = 2e-10 Identities = 36/188 (19%), Positives = 65/188 (34%), Gaps = 18/188 (9%) Query: 11 MSGTRKRTYQLLVTTALQLF-EQGMLP-TVSELAAHAGVSRATAYRYFPTQSDLISATVD 68 + T Q ++ AL+LF +QG+ ++ E+A AGV+R Y +F +SDL S + Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 69 ASLAPIIA-----WQPTPEDNTQQRITALLN-LAYPQMFKHEGALRGALQVSLQQWAKER 122 S + I P D L++ L + L + + E Sbjct: 65 LSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEF-VGEM 123 Query: 123 QSSEYTEKRF---IRGHRKEILLKVIEPLKAHYPQEMWDKVIKAFSLIYGSEVFLVMKDI 179 + ++ ++ L IE A +A ++ G + + Sbjct: 124 AVVQQAQRNLCLESYDRIEQTLKHCIE---AKMLPADLM-TRRAAIIMRG--YISGLMEN 177 Query: 180 WKMDDQQV 187 W Q Sbjct: 178 WLFAPQSF 185
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 30.3 bits (68), Expect = 0.002 Identities = 19/66 (28%), Positives = 24/66 (36%), Gaps = 5/66 (7%) Query: 58 NWLR---IRYLWVDKAYRGNNIGTELLQAMENTAKKKGAK--YAEVDTFSFQALPFYQKQ 112 NW I + V K YR +GT LL AK+ E + A FY K Sbjct: 85 NWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKH 144 Query: 113 GFEVFG 118 F + Sbjct: 145 HFIIGA 150
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 69.2 bits (169), Expect = 5e-16 Identities = 48/246 (19%), Positives = 113/246 (45%), Gaps = 4/246 (1%) Query: 6 WVALKTIWIKEVTRFGRIWVQTLIPPVITMSLYFVIFGNLIGKRIGDMGGVDYMQFIVPG 65 W+A +W + + + + +L+ + +Y G +G +G +GGV Y F+ G Sbjct: 16 WIA---VWRRNYIAWKKAALASLLGHLAEPLIYLFGLGAGLGVMVGRVGGVSYTAFLAAG 72 Query: 66 LIMMAVITNS-YANVSSSFFGAKFQRSIEELLVSPVPTHVVIAGFVGGGVARGICVGILV 124 ++ + +T + + + ++F + QR+ E +L + + ++ G + + G + Sbjct: 73 MVATSAMTAATFETIYAAFGRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAGI 132 Query: 125 TLVSLFFVPLEIHSWTMVVVTLLMTSIVFSLAGLLNAIFAKTFDDISIIPTFVLTPLTYL 184 +V+ + S + + +T + F+ G++ A ++D T V+TP+ +L Sbjct: 133 GVVAAALGYTQWLSLLYALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFL 192 Query: 185 GGVFYSLSLLPAFWQGVSKLNPIVYMISGFRYGFLGITDVSLTVTITVLCLFIAVFYIVA 244 G + + LP +Q ++ P+ + I R LG V + + LC++I + + ++ Sbjct: 193 SGAVFPVDQLPIVFQTAARFLPLSHSIDLIRPIMLGHPVVDVCQHVGALCIYIVIPFFLS 252 Query: 245 WYLIEK 250 L+ + Sbjct: 253 TALLRR 258
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 32.5 bits (74), Expect = 0.002 Identities = 17/83 (20%), Positives = 31/83 (37%), Gaps = 6/83 (7%) Query: 7 NCPLIILGSVVLLLSGCHSLTSKIDTTFLPPENGRTVKISVDVPDMAELLPMKVMYRSNL 66 L L+++G L ++ ++FLP E+ + +P A + + Sbjct: 535 GSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQK--VLDQ 592 Query: 67 CQKTYHNNEVP----KYTVPGFN 85 Y NE +TV GF+ Sbjct: 593 VTDYYLKNEKANVESVFTVNGFS 615
>PF03627#PapG Length = 336 Score = 30.7 bits (69), Expect = 0.005 Identities = 27/140 (19%), Positives = 55/140 (39%), Gaps = 40/140 (28%) Query: 159 VGACKISEGAVNLNYGDIDEASLSGAKRSETINVTCNLAMKVLVIASGSDSGRVPLRADK 218 +G C+ S ++ + +GD+ S + ++T++V+C+ VP Sbjct: 214 IGGCRPSAQSLEIKHGDLSINSANNHYAAQTLSVSCD----------------VPANIRF 257 Query: 219 SLYADLYLNNYPGEKGVTVNVPAGGSAPVSVS------STLRTN---------------- 256 L + Y K +V + G + VSV+ +T+R Sbjct: 258 MLLRNT-TPTYSHGKKFSVGLGHGWDSIVSVNGVDTGETTMRWYKAGTQNLTIGSRLYGE 316 Query: 257 -GRVAPGRFSGSGSIILTMP 275 ++ PG SGS ++++ +P Sbjct: 317 SSKIQPGVLSGSATLLMILP 336
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 411 bits (1058), Expect = e-143 Identities = 101/431 (23%), Positives = 180/431 (41%), Gaps = 15/431 (3%) Query: 18 PKKFLVIGWTVVLLGLAIFIFWAAFAPLDKGVPAIGNVVISGNKKSVQSSVEGIITHIFV 77 ++ ++ + ++ L I + ++ A G + SG K ++ I+ I V Sbjct: 54 SRRPRLVAYFIMG-FLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIV 112 Query: 78 KNGDPVSAGQTLIQLSPIQSQALVKSLSEQYDNLLITQQRLYAELNQQTSFKLN----NS 133 K G+ V G L++L+ + ++A + Q R KL Sbjct: 113 KEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPD 172 Query: 134 DKYYSSTENREKLL---LQQNRLLNEKSAELISEINGYKAAIDGITGRLTHLKRSIQNKK 190 + Y+ + E L L + + ++ + E+N K + +T + I + Sbjct: 173 EPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLT-----VLARINRYE 227 Query: 191 SQISNLQNQLNDLQILANEGYIPRHRYQEMVRELAENNNQLNETFGQISALEKQKLEYEQ 250 + +++L+D L ++ I +H E + E N+L Q+ +E + L ++ Sbjct: 228 NLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKE 287 Query: 251 RILQRNANFHQLARTELNKIQLQISETEKQLIIETDKLAKMAIIAPISGTVMDLSVFTQG 310 F +L + I +L ++ I AP+S V L V T+G Sbjct: 288 EYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEG 347 Query: 311 GFVKTGQTLMDIVPEDHQLVIEARLAPHLIDKVTPGLPVDLIFSAFNQNTTPKIPGEVTI 370 G V T +TLM IVPED L + A + I + G + AF + G+V Sbjct: 348 GVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKN 407 Query: 371 ISADRLIDERTTEPYYQVLINIKDYTLLADNKN-KLKAGMPVDVFIKTGDRSLLNYLFKP 429 I+ D + D+R + V+I+I++ L NKN L +GM V IKTG RS+++YL P Sbjct: 408 INLDAIEDQRL-GLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGMRSVISYLLSP 466 Query: 430 VLDRLHTSLTE 440 + + + SL E Sbjct: 467 LEESVTESLRE 477
>CABNDNGRPT#NodO calcium binding signature. Length = 479 Score = 369 bits (949), Expect = e-126 Identities = 217/463 (46%), Positives = 281/463 (60%), Gaps = 34/463 (7%) Query: 34 PSFDYDTAGKHIAREDSTWNGKYVIGQPAEVTYSFPKWEGKFNQFGNKNPYEFNELQKEH 93 S+ D A I RE+ +WNG V G+ A +T+ F + G+ +FN Q E Sbjct: 46 TSYSIDQAAAQITRENVSWNGTNVFGKSANLTFKFLQSVSSIPS-GDTGFVKFNAEQIEQ 104 Query: 94 ARKSLDAWSDIANIKFTEVAVGNVDGMKASDVKTDITFGN-IYDPNGTF----QAYATLP 148 A+ SL +WSD+AN+ FTEV + +ITFGN D +G QAYA P Sbjct: 105 AKLSLQSWSDVANLTFTEVT---------GNKSANITFGNYTRDASGNLDYGTQAYAYYP 155 Query: 149 NTYAYGKDLSGQAWFSDYHYAGNTTPELGNYGRLTIIHEIGHTLGLMHPGDYNAGQNVPG 208 Y +G +W+ +Y+ + P YGR T HEIGH LGL HPG+YNAG+ P Sbjct: 156 GNYQG----AGSSWY-NYNQSNIRNPGSEEYGRQTFTHEIGHALGLAHPGEYNAGEGDPS 210 Query: 209 YLKSDYAEDSRQYTVMSYWDEYETGAHFQGAYAGAPLLHDISAMQYLYGANTTTRTGDDV 268 Y + YAEDS Q+++MSYW E ETGA + G Y GAP++ DI+A+Q LYGAN TTRTGD V Sbjct: 211 YNDAVYAEDSYQFSIMSYWGENETGADYNGHYGGAPMIDDIAAIQRLYGANMTTRTGDSV 270 Query: 269 YGFNSNTGIDYYTATDSNDKLIFSVWDSGGNDTFDFSGFYQDQLIDLRAGNFSDVGGLQK 328 YGFNSNT D+YTATDS+ LIFSVWD+GG DTFDFSG+ +Q I+L G+FSDVGGL+ Sbjct: 271 YGFNSNTDRDFYTATDSSKALIFSVWDAGGTDTFDFSGYSNNQRINLNEGSFSDVGGLKG 330 Query: 329 NVSIAQNVTIENAIGGFGNDIIHGNDADNTLIGGEGDDIIYGHSGNNTIYGGRGQDTLHG 388 NVSIA VTIENAIGG GNDI+ GN ADN L GG G+D++YG +G +T+YGG G+DT Sbjct: 331 NVSIAHGVTIENAIGGSGNDILVGNSADNILQGGAGNDVLYGGAGADTLYGGAGRDTFVY 390 Query: 389 GTGSNTFIYKEIADSLVSAADKIMDFKTGIDKIDLSTLIQDTFSSKILNFVDNFTGNAGE 448 G+G DS V+A D I DF+ GIDKIDLS ++ D FTG E Sbjct: 391 GSGQ---------DSTVAAYDWIADFQKGIDKIDLSAF---RNEGQLSFVQDQFTGKGQE 438 Query: 449 ATLSYNEVTNASELAINAYGYNYNPDFKIDIVGFVNYETDFIV 491 L ++ + + L ++ + + DF + IVG +D IV Sbjct: 439 VMLQWDAANSITNLWLH-EAGHSSVDFLVRIVGQAAQ-SDIIV 479
>CABNDNGRPT#NodO calcium binding signature. Length = 479 Score = 213 bits (544), Expect = 6e-64 Identities = 115/283 (40%), Positives = 156/283 (55%), Gaps = 14/283 (4%) Query: 273 KNNKYQPGTYHY--KVVLHEVGHALGLSHSWQY------LEYKDKNHVLASLKYSVMGYD 324 ++N PG+ Y + HE+GHALGL+H +Y Y D + S ++S+M Y Sbjct: 170 QSNIRNPGSEEYGRQTFTHEIGHALGLAHPGEYNAGEGDPSYNDAVYAEDSYQFSIMSYW 229 Query: 325 IPTSEHADFGGLYPMTFMLLDILLLQQLYGENMTTRLENNIYGFHSNTGRVAYSLKSIED 384 AD+ G Y M+ DI +Q+LYG NMTTR +++YGF+SNT R Y+ Sbjct: 230 GENETGADYNGHYGGAPMIDDIAAIQRLYGANMTTRTGDSVYGFNSNTDRDFYTATDSSK 289 Query: 385 KLVSCIWDSGGIDTLDFSLYTVNQVINLNEGSFSDIGGLRSNISIAYKTIIENAIGGSGH 444 L+ +WD+GG DT DFS Y+ NQ INLNEGSFSD+GGL+ N+SIA+ IENAIGGSG+ Sbjct: 290 ALIFSVWDAGGTDTFDFSGYSNNQRINLNEGSFSDVGGLKGNVSIAHGVTIENAIGGSGN 349 Query: 445 DTIIGNSANNELIGGDGNDTIKGGLGNDHLYGGMGNDILYGDIGNDYLYGG--IGDDILH 502 D ++GNSA+N L GG GND + GG G D LYGG G D G D D Sbjct: 350 DILVGNSADNILQGGAGNDVLYGGAGADTLYGGAGRDTFVYGSGQDSTVAAYDWIADFQK 409 Query: 503 GGMGNDILHGSMGNDYLYGNKGNDKLFGGDGDDTLVDYYGNNT 545 G D+ + N+ F G G + ++ + N+ Sbjct: 410 GIDKIDLS--AFRNEGQLSFV--QDQFTGKGQEVMLQWDAANS 448 Score = 121 bits (305), Expect = 2e-31 Identities = 61/249 (24%), Positives = 94/249 (37%), Gaps = 17/249 (6%) Query: 440 GGSGHDTIIGNSANNELIGGDGNDTIKGGLGNDHLYGGMGNDILYGDIGNDYLYGGIGDD 499 G D I A L G N T + G D + L + D Sbjct: 244 GAPMIDDIA---AIQRLYGA--NMTTRTGDSVYGFNSNTDRDFYTATDSSKALIFSVWDA 298 Query: 500 ILHGGMGNDILHGSMGNDYLYGNKGNDK-LFGGDGDDTLVDYYGNNTFIGGKGNDLLFSI 558 GG G N + N+G+ + G G+ ++ IGG GND+L Sbjct: 299 ---GGTDTFDFSGYSNNQRINLNEGSFSDVGGLKGNVSIAHGVTIENAIGGSGNDILVGN 355 Query: 559 SKAGRNELQGGEGNDIFYCGLGTNLLYGEQGNDTFNFLCYKGAKSYN--LIFDFNTNEDK 616 S N LQGG GND+ Y G G + LYG G DTF + + + I DF DK Sbjct: 356 S--ADNILQGGAGNDVLYGGAGADTLYGGAGRDTFVYGSGQDSTVAAYDWIADFQKGIDK 413 Query: 617 IIFVDQNYKKIDISKMKRVEQLSGNENEIVLHNDIHTNKTTITISTANNDHHSTIFIKLE 676 I ++ + Q +G E++L D + T + + A + +++ Sbjct: 414 IDLSA--FRNEGQLSFVQD-QFTGKGQEVMLQWDAANSITNLWLHEAGH-SSVDFLVRIV 469 Query: 677 GILSYNDLL 685 G + +D++ Sbjct: 470 GQAAQSDII 478
>CABNDNGRPT#NodO calcium binding signature. Length = 479 Score = 191 bits (486), Expect = 7e-56 Identities = 108/246 (43%), Positives = 134/246 (54%), Gaps = 9/246 (3%) Query: 280 GSFVYHTFIHELGHSLGLFHIWEYILNEKHK-------VLDSIKYSVMSYKCPDIKDADF 332 + TF HE+GH+LGL H EY E DS ++S+MSY + AD+ Sbjct: 179 EEYGRQTFTHEIGHALGLAHPGEYNAGEGDPSYNDAVYAEDSYQFSIMSYWGENETGADY 238 Query: 333 GGLYPMTFMLVDILLLQYLYGENMTTRLENNTYGFNSNTGRAAYSLNSIEDKLVSCIWDA 392 G Y M+ DI +Q LYG NMTTR ++ YGFNSNT R Y+ L+ +WDA Sbjct: 239 NGHYGGAPMIDDIAAIQRLYGANMTTRTGDSVYGFNSNTDRDFYTATDSSKALIFSVWDA 298 Query: 393 GGIDTLDFSLYTVNQVINLNEGCFSDIGGLRSNISIAYKTIIENAIGGKGDDTLIGNPFD 452 GG DT DFS Y+ NQ INLNEG FSD+GGL+ N+SIA+ IENAIGG G+D L+GN D Sbjct: 299 GGTDTFDFSGYSNNQRINLNEGSFSDVGGLKGNVSIAHGVTIENAIGGSGNDILVGNSAD 358 Query: 453 NNLIGGDGNDLFYGGDGNDLFYGGSGNDVIYGELGNDVLYG--DDGDDMLIDYYGANMLD 510 N L GG GND+ YGG G D YGG+G D G D D D ++ Sbjct: 359 NILQGGAGNDVLYGGAGADTLYGGAGRDTFVYGSGQDSTVAAYDWIADFQKGIDKIDLSA 418 Query: 511 GGKGND 516 Sbjct: 419 FRNEGQ 424 Score = 48.4 bits (115), Expect = 7e-08 Identities = 39/251 (15%), Positives = 68/251 (27%), Gaps = 60/251 (23%) Query: 451 FDNNLIGGDGNDLFYGGDGNDLFYGG----SGNDVIYGELGNDVLYGDDGDDML------ 500 + N G D N + G D N + D Sbjct: 229 WGENETGADYNGHYGGAPMIDDIAAIQRLYGANMTTRTGDSVYGFNSNTDRDFYTATDSS 288 Query: 501 -------IDYYGANMLD--GGKGNDRICVASTD-------------RGLPGRNIILGGEG 538 D G + D G N RI + +GG G Sbjct: 289 KALIFSVWDAGGTDTFDFSGYSNNQRINLNEGSFSDVGGLKGNVSIAHGVTIENAIGGSG 348 Query: 539 DDEIYLGTGTHRITGGQGNDAFNFFCYEGVESNSSIW---------------DFEKNKDK 583 +D + + + + GG GND G +++ D Sbjct: 349 NDILVGNSADNILQGGAGNDVLY-----GGAGADTLYGGAGRDTFVYGSGQDSTVAAYDW 403 Query: 584 ITLITRDYRKIDISKMK-------KVDKLSGSKNEFSLNYNKPANKTIIDVSTSSNDNKS 636 I + KID+S + D+ +G E L ++ + T + + + + + Sbjct: 404 IADFQKGIDKIDLSAFRNEGQLSFVQDQFTGKGQEVMLQWDAANSITNLWLHEAGHSSVD 463 Query: 637 IVHIEIVGIFN 647 + + IVG Sbjct: 464 FL-VRIVGQAA 473 Score = 31.1 bits (70), Expect = 0.014 Identities = 20/106 (18%), Positives = 28/106 (26%), Gaps = 4/106 (3%) Query: 458 GDGNDLFYGGDGNDLFYGGSGNDVIYGELGNDVLYGDDGDDMLIDYYGANMLDGGKGNDR 517 G L + G+ N S ND +Y E + G D Sbjct: 191 GHALGLAHPGEYNAGEGDPSYNDAVYAEDSYQFSIMSYWGENETGADYNGHYGGAPMIDD 250 Query: 518 ICVASTDRGLPGRN-IILGGEGDDEIYLGTGTHRITGGQGNDAFNF 562 I + + L G N G+ T T + A F Sbjct: 251 I---AAIQRLYGANMTTRTGDSVYGFNSNTDRDFYTATDSSKALIF 293
>CABNDNGRPT#NodO calcium binding signature. Length = 479 Score = 185 bits (470), Expect = 1e-53 Identities = 107/262 (40%), Positives = 137/262 (52%), Gaps = 9/262 (3%) Query: 264 STDVLLNETMKSKHKLGSYEYLCFIHELGHALGLMHINVY-------LKNIKNDVILTYK 316 S+ N++ Y F HE+GHALGL H Y N +Y+ Sbjct: 163 SSWYNYNQSNIRNPGSEEYGRQTFTHEIGHALGLAHPGEYNAGEGDPSYNDAVYAEDSYQ 222 Query: 317 YSVMAYQFADIKDADFAGLYPMTFMLVDILLLQYLYGPNMTTRLENNTYGFHSNTGRAAY 376 +S+M+Y + AD+ G Y M+ DI +Q LYG NMTTR ++ YGF+SNT R Y Sbjct: 223 FSIMSYWGENETGADYNGHYGGAPMIDDIAAIQRLYGANMTTRTGDSVYGFNSNTDRDFY 282 Query: 377 SLNSIEDKLVSCIWDAGGIDTLDFSLYTVNQVINLNEGCFSDIGGLRSNISIAYKTIIEN 436 + L+ +WDAGG DT DFS Y+ NQ INLNEG FSD+GGL+ N+SIA+ IEN Sbjct: 283 TATDSSKALIFSVWDAGGTDTFDFSGYSNNQRINLNEGSFSDVGGLKGNVSIAHGVTIEN 342 Query: 437 AIGGKGDDTLIGNPFDNNLIGGDGNDLFYGGDGNDLFYGGSGNDVIYGELGNDVLYG--D 494 AIGG G+D L+GN DN L GG GND+ YGG G D YGG+G D G D D Sbjct: 343 AIGGSGNDILVGNSADNILQGGAGNDVLYGGAGADTLYGGAGRDTFVYGSGQDSTVAAYD 402 Query: 495 DGDDMLIDYYGANMLDGGKGND 516 D ++ Sbjct: 403 WIADFQKGIDKIDLSAFRNEGQ 424 Score = 30.3 bits (68), Expect = 0.026 Identities = 19/106 (17%), Positives = 27/106 (25%), Gaps = 4/106 (3%) Query: 458 GDGNDLFYGGDGNDLFYGGSGNDVIYGELGNDVLYGDDGDDMLIDYYGANMLDGGKGNDR 517 G L + G+ N S ND +Y E + G D Sbjct: 191 GHALGLAHPGEYNAGEGDPSYNDAVYAEDSYQFSIMSYWGENETGADYNGHYGGAPMIDD 250 Query: 518 ICVASTDRGLPGRN-IILGGEGDDEIYLGTGTHRITGGQGNDTFNF 562 I + + L G N G+ T T + F Sbjct: 251 I---AAIQRLYGANMTTRTGDSVYGFNSNTDRDFYTATDSSKALIF 293
>CABNDNGRPT#NodO calcium binding signature. Length = 479 Score = 181 bits (461), Expect = 2e-52 Identities = 106/262 (40%), Positives = 136/262 (51%), Gaps = 9/262 (3%) Query: 259 STDVLLNETMKSKHKLGSQIYYVFLHELGHALGLEHIDAY-------LKNIKNSAIETYK 311 S+ N++ F HE+GHALGL H Y N A ++Y+ Sbjct: 163 SSWYNYNQSNIRNPGSEEYGRQTFTHEIGHALGLAHPGEYNAGEGDPSYNDAVYAEDSYQ 222 Query: 312 YTVMGMGFADIKDADFGGLYPMTFMLVDILLLQYLYGPNMTTRLENNTYGFNSNTGRAAY 371 +++M + AD+ G Y M+ DI +Q LYG NMTTR ++ YGFNSNT R Y Sbjct: 223 FSIMSYWGENETGADYNGHYGGAPMIDDIAAIQRLYGANMTTRTGDSVYGFNSNTDRDFY 282 Query: 372 SLKSIEDKLVSCIWDAGGIDTLDFSLYTVNQVINLNEGCFSDIGGLRSNISIAYKTIIEN 431 + L+ +WDAGG DT DFS Y+ NQ INLNEG FSD+GGL+ N+SIA+ IEN Sbjct: 283 TATDSSKALIFSVWDAGGTDTFDFSGYSNNQRINLNEGSFSDVGGLKGNVSIAHGVTIEN 342 Query: 432 AIGGKGDDTLIGNPFDNNLIGGDGNDLFYGGDGNDLFYGGSGNDVIYGEMGNDVLYG--D 489 AIGG G+D L+GN DN L GG GND+ YGG G D YGG+G D G D D Sbjct: 343 AIGGSGNDILVGNSADNILQGGAGNDVLYGGAGADTLYGGAGRDTFVYGSGQDSTVAAYD 402 Query: 490 DGDDMLIDYYGANMLDGGKGND 511 D ++ Sbjct: 403 WIADFQKGIDKIDLSAFRNEGQ 424
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 636 bits (1641), Expect = 0.0 Identities = 216/859 (25%), Positives = 378/859 (44%), Gaps = 57/859 (6%) Query: 17 VVLLTMSISVFSAYATEFNIDVLDAEDIQNIDMSQFSIAGYVPPGDYVLTVFVNGQRLGA 76 V + + S+ FN L + D+S+F +PPG Y + +++N + Sbjct: 32 VACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGYMA- 90 Query: 77 PRDITVLEQKTQTQAI-CIPADLLDSIGLKESVKPKVTVYPNSQCLDL-SVLKGMQTVID 134 RD+T ++ + C+ L S+GL + + + + C+ L S++ +D Sbjct: 91 TRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLTSMIHDATAQLD 150 Query: 135 LPTLSLKITIPQLWMEYRDPYWTPPALWEEGINGAFLDYSANVSITEEKEGDKRTYLSTN 194 + L +TIPQ +M R + PP LW+ GIN L+Y+ + + + + G Y N Sbjct: 151 VGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNSHYAYLN 210 Query: 195 GTAGINLGVWRFRGDYSAIYQKKRGGRQSQEIHDFDFSRLYGFTSLKKLASILTIGENYF 254 +G+N+G WR R + + Y S+ + + + L S LT+G+ Y Sbjct: 211 LQSGLNIGAWRLRDNTTWSYNSSDSSSGSKN--KWQHINTWLERDIIPLRSRLTLGDGYT 268 Query: 255 YSDVFESWQYSGISLESDDRMLPPKLVGYAPEITGVADTNATVIVRSQNRVLLETTVPPG 314 D+F+ + G L SDD MLP G+AP I G+A A V ++ + +TVPPG Sbjct: 269 QGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPPG 328 Query: 315 PFRIQTLD-SGVRGILDITIREENGEEKKFSISTASLPYLTRPGRLIYKLVMGKTRYDGH 373 PF I + +G G L +TI+E +G + F++ +S+P L R G Y + G+ R Sbjct: 329 PFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYRSGNA 388 Query: 374 HLTGKPVFSGEFSYGLSNAWSLYGGTQFNSDYQATAIGIGRDLFSFGALSLDITQSFARF 433 F +GL W++YGGTQ Y+A GIG+++ + GALS+D+TQ+ + Sbjct: 389 QQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQANSTL 448 Query: 434 -TDKKIKGRSYRLNYAKSFDALRTDITFAGYRFAARDYRTLTQFMDQRRTGYDIRS---- 488 D + G+S R Y KS + T+I GYR++ Y R GY+I + Sbjct: 449 PDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGV 508 Query: 489 ----------------PKENYQIYINKYFDNF-NISLNYQYSTYWQDKP-QTQYGLYAST 530 + Q+ + + + L+ + TYW Q+ +T Sbjct: 509 IQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSNVDEQFQAGLNT 568 Query: 531 NISIPMLSQQNANISLSATRTERDSGYQDDAINLYLTIPLYKGHS---------ISFSES 581 N +S S T+ G +D + L + IP S S S Sbjct: 569 AFEDI-----NWTLSYSLTKNAWQKG-RDQMLALNVNIPFSHWLRSDSKSQWRHASASYS 622 Query: 582 YSRIGKSNQYSHRASYSGY---SDRDNYSLNVGYSHGEEIDSQSSISGYYSRDFSQANLS 638 S + + ++ A G + +YS+ GY+ G + +S S+ + N + Sbjct: 623 MSH-DLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNAN 681 Query: 639 ANASYVPQQYRSVGASINSGITATTQGIALHRSANGDTRLMIETPGVGDVPLDSG-VIKT 697 S+ + + ++ G+ A G+ L + DT ++++ PG D +++ ++T Sbjct: 682 IGYSHSD-DIKQLYYGVSGGVLAHANGVTLGQP-LNDTVVLVKAPGAKDAKVENQTGVRT 739 Query: 698 NHFGLAVIPNVNSYRKSTVSINTSQLPENIETLESTTDITLTKGAIGYRSLSVMKGEKLF 757 + G AV+P YR++ V+++T+ L +N++ + ++ T+GAI G KL Sbjct: 740 DWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKLL 799 Query: 758 AIISLNDGKKPPFGASVRNADNRELGIVGEDGVTWLVGISSKEKLSVYW--AGKKQCEL- 814 ++ ++ K PFGA V + ++ GIV ++G +L G+ K+ V W C Sbjct: 800 MTLT-HNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCVAN 858 Query: 815 -SLPEDLASPT-SMLLLPC 831 LP + + L C Sbjct: 859 YQLPPESQQQLLTQLSAEC 877
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 52.7 bits (126), Expect = 1e-10 Identities = 9/41 (21%), Positives = 25/41 (60%) Query: 28 VIQSGIEMFAEKGYISSDICKILEKVGIPKGSFYYYFGSKE 68 ++ + +F+++G S+ + +I + G+ +G+ Y++F K Sbjct: 16 ILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKS 56
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 28.0 bits (62), Expect = 0.029 Identities = 13/56 (23%), Positives = 21/56 (37%), Gaps = 1/56 (1%) Query: 151 DKADINIEEAKSLSFKIKLQAKEVGLKGGFSLKSIPTEFRNIFPPFVLNTQASSNT 206 D I ++E S S A G K F ++P + +F + +AS Sbjct: 76 DTLTIVLQENVSASKSSSANASRDG-KTNFGFDTVPRYLQGLFGNARADVEASGGN 130
>TRNSINTIMINR#Translocated intimin receptor (Tir) signature. Length = 549 Score = 30.5 bits (68), Expect = 4e-04 Identities = 16/60 (26%), Positives = 33/60 (55%), Gaps = 6/60 (10%) Query: 16 QMEREAFVNSQEEKISVDEVMDSLPEELLCMDLARKLNPVFEISPQALDAVLAGIRTAIQ 75 Q+ +EAF N + +K+++D +++P L D+ V +I+ QA +A + A++ Sbjct: 285 QLTQEAFKNPENQKVNIDANGNAIPSGELKDDI------VEQIAQQAKEAGEVARQQAVE 338
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 33.9 bits (77), Expect = 0.003 Identities = 39/216 (18%), Positives = 78/216 (36%), Gaps = 18/216 (8%) Query: 497 SKLALLKEEKFQRDIKNAREKAARDEEERKKAQFRADQELKRQYETAEEKHQRL------ 550 +L L K E+ R A EKA ++ E+R+K R E +RQ + AE + +RL Sbjct: 128 ERLRLAKAEEKARKEAEAAEKAFQEAEQRRKEIEREKAETERQLKLAEAEEKRLAALSEE 187 Query: 551 ------LKEIINNADASQAAKDEAIRREKERYEKEKAKGKGKTPTYRPDYGTRVDESANQ 604 ++ ++ A + D I+ R + T Q Sbjct: 188 AKAVEIAQKKLSAAQSEVVKMDGEIKTLNSRLSSSIHARDAEMKTLAGK-----RNELAQ 242 Query: 605 ALLSLQAQLKVLKEHKTVSDVISSERKKLWDMEAKISILEEA-QKTRQLTKDEKALLAKK 663 A + +++K+ ++ R ++ + +K +Q+T E + Sbjct: 243 ASAKYKELDELVKKLSPRANDPLQNRPFFEATRRRVGAGKIREEKQKQVTASETRINRIN 302 Query: 664 DYILASQEALAIAGDEVKLQELHNRELDKQLKRVEE 699 I Q+A++ + E ++ LK+ + Sbjct: 303 ADITQIQKAISQVSNNRNAGIARVHEAEENLKKAQN 338
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 27.4 bits (60), Expect = 0.004 Identities = 17/57 (29%), Positives = 30/57 (52%), Gaps = 2/57 (3%) Query: 4 SEMAKDIETLQTRTLALEYIIQ--VMIRNMSDIEKEKLISELNKVSHDSPVTIEAFG 58 S+ A E +Q + +E++ Q + N+S+ EKEK +E+ DS ++A G Sbjct: 384 SQRALSQEEIQNKIDFMEFLAQNNAKLDNLSEKEKEKFRTEIKDFQKDSKAYLDALG 440
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 34.4 bits (79), Expect = 0.004 Identities = 18/157 (11%), Positives = 52/157 (33%), Gaps = 17/157 (10%) Query: 909 QARIEGDKTEAQQRQSLATQLR--GDYTGNDLSKVTAGLISAEKQARVSGDQAEAKARQS 966 A + KT++ Q+ Q R +L+K+ + E + ++ + Sbjct: 131 GAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSL 190 Query: 967 LETR----------MNGNVSAINKSLETLTSKQQAQTQEISTLNSNLKGK---ADSSVVN 1013 ++ + N+ T+ ++ S L + Sbjct: 191 IKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIA 250 Query: 1014 ALNTRVTNLDGKVMSATSQVQTLSSKLDTVKADLTES 1050 V + K + A ++++ S+L+ +++++ + Sbjct: 251 KH--AVLEQENKYVEAVNELRVYKSQLEQIESEILSA 285
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 31.7 bits (72), Expect = 0.002 Identities = 14/42 (33%), Positives = 25/42 (59%), Gaps = 3/42 (7%) Query: 14 VDNAPRMQDYTLEV--PEGRDMMLLDALIQLKEKDPTLSFRR 53 ++N + T+E P+ R+M LLDAL+++ + DP L + Sbjct: 339 IENPLPLLQTTVEPSKPQQREM-LLDALLEISDSDPLLRYYV 379
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 34.0 bits (78), Expect = 0.001 Identities = 25/175 (14%), Positives = 52/175 (29%), Gaps = 10/175 (5%) Query: 48 EVPASEAGVLDSILEEEGATVGSRQLLGRIRLGDSTGIPADVKPAQDTTPAQRQSADIVA 107 E+ E ++ I+ +EG +V +L ++L + G AD Q + R Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVL--LKL-TALGAEADTLKTQSSLLQARLEQ---- 150 Query: 108 KESNDALSPTARRLVAEHDINPADVKGSGVGGRLTRQDIESHVANNKSAAAATAEVSQAP 167 LS + P + V + + + Sbjct: 151 -TRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNL 209 Query: 168 LSHRSEKRVPMTRLRKRVAERLLEAKNTTAMLTTFNE--INMQPIKNLRAQYGEA 220 R+E+ + R+ + +E + ++ I + +Y EA Sbjct: 210 DKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEA 264
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 81.8 bits (202), Expect = 8e-19 Identities = 75/358 (20%), Positives = 152/358 (42%), Gaps = 14/358 (3%) Query: 6 QIAIIFLLGFFIDCINIFMSAIALPAIAADMKVSIVSITWVSNSYILGLTLIIPLSHWLS 65 QI I + F +N + ++LP IA D S WV+ +++L ++ + LS Sbjct: 14 QILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLS 73 Query: 66 QRFGVRVLIVSSMLIFSASVALVGYSHSFFE-LILWRFIQGLSGGLLIPIGQALTFQYFQ 124 + G++ L++ ++I + HSFF LI+ RFIQG + + +Y Sbjct: 74 DQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIP 133 Query: 125 GHERSKVSTLIMAVALIAPAISPTIGGFIVDAVSWRWVFYSNVPF-SLLTAFLAFIWVKE 183 R K LI ++ + + P IGG I + W ++ +P +++T +K+ Sbjct: 134 KENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLL--LIPMITIITVPFLMKLLKK 191 Query: 184 SKSQENIIPDLKGILLISIIIVSGLCALSAYGEYHSTQLALVISFFAALFSLLYYRHYKQ 243 + D+KGI+L+S+ IV + ++Y + V+SF ++ +H ++ Sbjct: 192 EVRIKGHF-DIKGIILMSVGIVFFMLFTTSYSISF--LIVSVLSFL------IFVKHIRK 242 Query: 244 SLSPVINLNLLKNRNLSLSIFLYYCIPGVFTGVNILAIFYLQQYLHFSGQGTGS-FMLLY 302 P ++ L KN + + I G G + + ++ S GS + Sbjct: 243 VTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPG 302 Query: 303 AIGAFISIIVGGALYNKLGMKRLAIFALILHSIGIVLLALVNKESDLPLLILAYLMMG 360 + I +GG L ++ G + + S+ + + + + + + I+ ++G Sbjct: 303 TMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLG 360 Score = 29.8 bits (67), Expect = 0.025 Identities = 24/66 (36%), Positives = 37/66 (56%), Gaps = 6/66 (9%) Query: 298 FMLLYAIGAFISIIVGGALYNKLGMKRLAIFALILHSIGIVLLALVNKESDLPLLILAYL 357 FML ++IG V G L ++LG+KRL +F +I++ G V+ + S LLI+A Sbjct: 58 FMLTFSIGT----AVYGKLSDQLGIKRLLLFGIIINCFGSVIGFV--GHSFFSLLIMARF 111 Query: 358 MMGIGG 363 + G G Sbjct: 112 IQGAGA 117
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 61.2 bits (148), Expect = 3e-12 Identities = 33/203 (16%), Positives = 71/203 (34%), Gaps = 7/203 (3%) Query: 56 MVDPNAVVQEYNQQKAQQANVQKAEQERKARAQQQEEELRQQQIKEQERLKALEVERLQA 115 + + N YN + ++ Q + +E R+ V Sbjct: 971 LRNVNGRYDLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAP 1030 Query: 116 KEAAEAQRREAATAAAKAKEEQKQAEEAAAQAKAERDRILKEQADAKAKAEAEAKKQAEL 175 +E A + ++K +K E+ A + A+ + KE AK+ +A Q Sbjct: 1031 ATPSETTETVAENSKQESKTVEKN-EQDATETTAQNREVAKE-----AKSNVKANTQTNE 1084 Query: 176 AAKQKAEEAKAK-AEAEAKAKAEADAKAKAEADAKAKAAAEAKAKAAAEAKAKAAAQQQS 234 A+ +E + + E + A E + KAK E + + + + +++ Q Sbjct: 1085 VAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAE 1144 Query: 235 KAVDSLLDGLVAQGDKQSGASAA 257 A ++ + + Q+ +A Sbjct: 1145 PARENDPTVNIKEPQSQTNTTAD 1167 Score = 49.7 bits (118), Expect = 1e-08 Identities = 31/219 (14%), Positives = 72/219 (32%), Gaps = 17/219 (7%) Query: 68 QQKAQQANVQKAEQ---ERKARAQQQEEELR-------QQQIKEQERLKALEVERLQAKE 117 K + V+K EQ E A+ ++ +E + Q Q + E + + KE Sbjct: 1043 NSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKE 1102 Query: 118 AA--EAQRREAATAAAKAKEEQKQAEEAAAQAKAERDRI----LKEQADAKAKAEAEAKK 171 A E + + + + ++ + Q ++E + +E E +++ Sbjct: 1103 TATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQT 1162 Query: 172 QAELAAKQKAEEAKAKAEAEAKAKAEADAKAKAEADAKAKAAAEAKAKAAAEAKAKAAAQ 231 +Q A+E + E + + + A + +E+ K + Sbjct: 1163 NTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNR 1222 Query: 232 QQSKAVDSLLDGLVAQGDKQSGASAAGQGGGNRSGANAA 270 + ++V S+ + + S + NA Sbjct: 1223 HR-RSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAV 1260 Score = 47.0 bits (111), Expect = 8e-08 Identities = 26/192 (13%), Positives = 59/192 (30%), Gaps = 17/192 (8%) Query: 65 EYNQQKAQQANVQKAEQERKARAQQQEE---ELRQQQ--IKEQERLKALEVERLQAKEAA 119 E Q ++ Q E + A +++E+ E + Q K ++ + + + A Sbjct: 1084 EVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQA 1143 Query: 120 EAQRREAATAAAKAKEEQKQAEEAAAQAKAERDR-----ILKEQADAKAKAEAEAKKQAE 174 E R T K + Q Q E + + + E + Sbjct: 1144 EPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTT 1203 Query: 175 LAAKQKAEEAKAKAEAEAKAK-------AEADAKAKAEADAKAKAAAEAKAKAAAEAKAK 227 A Q +++ + + + + + + D A + + + Sbjct: 1204 PATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSD 1263 Query: 228 AAAQQQSKAVDS 239 A A+ Q A++ Sbjct: 1264 ARAKAQFVALNV 1275
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 116 bits (292), Expect = 4e-34 Identities = 37/129 (28%), Positives = 56/129 (43%), Gaps = 6/129 (4%) Query: 37 VPVTEQGPTAEELARQQLEQLKQTNIVYFGFDKYDVTSEYAQLLDAHAAFLRAN--PSVR 94 PV P + + LK + V F F+K + E LD + L Sbjct: 197 APVVAPAPAPAPEVQTKHFTLK--SDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGS 254 Query: 95 ITIEGHADERGTPEYNIALGERRANAVKMYLQGKGVSADQLAIVSYGKEKPAVLGHDEAA 154 + + G+ D G+ YN L ERRA +V YL KG+ AD+++ G+ P V G+ Sbjct: 255 VVVLGYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPADKISARGMGESNP-VTGN-TCD 312 Query: 155 YAKNRRAVL 163 K R A++ Sbjct: 313 NVKQRAALI 321
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 27.9 bits (62), Expect = 0.040 Identities = 11/55 (20%), Positives = 19/55 (34%), Gaps = 1/55 (1%) Query: 48 RISNAHSQLLTQLQQQLADSQRDIDMLRGQIQENQYQLNQVVERQRNIYQQLDSL 102 S Q T Q Q + ++D R + ++N+ R +LD Sbjct: 187 LTSLIKEQFST-WQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDF 240 Score = 27.9 bits (62), Expect = 0.048 Identities = 3/45 (6%), Positives = 22/45 (48%) Query: 57 LTQLQQQLADSQRDIDMLRGQIQENQYQLNQVVERQRNIYQQLDS 101 + + + + ++ ++ + + Q+++ + ++ E + + Q + Sbjct: 254 VLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKN 298
>PF05860#haemagglutination activity domain. Length = 117 Score = 81.0 bits (200), Expect = 5e-20 Identities = 24/121 (19%), Positives = 41/121 (33%), Gaps = 21/121 (17%) Query: 42 TINQQNNIPIINIATPNDSGVSHNRFNVFNVNKQGAVLNNSQVDANSQLAKKISANKNLK 101 I + N II T S + H+ F F+V G N+ Sbjct: 14 NITTEGNTRIIERGTQAGSNLFHS-FQEFSVPTSGTAFFNNP------------------ 54 Query: 102 GNTANLIINEVVGNSRSQLLGKLEVAGQQADVLIAIPNGISCDGCSFINTPSITLTTGKP 161 II+ V G S S + G + A++ + PNGI + ++ + + Sbjct: 55 -TNIQNIISRVTGGSVSNIDGLIRANAT-ANLFLINPNGIIFGQNARLDIGGSFVGSTAN 112 Query: 162 Q 162 + Sbjct: 113 R 113
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 45.1 bits (106), Expect = 2e-06 Identities = 50/344 (14%), Positives = 116/344 (33%), Gaps = 18/344 (5%) Query: 328 TDYQAASDRLNLVQNAVRQQEKIDRYVADVEEITFRLEEQSEVVEEATSKKEELEARVGS 387 T+ +A + + QE+ D++ + + + + S + +EL + + Sbjct: 37 TNEVSAVATRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSN 96 Query: 388 AEEEVDELKSQLADYQQALDVQQTRAIQYRQAVQALERAK--AQCGIDDLDETNAELWAE 445 A+E++ + L++ + + R +A++ I L+ A L A Sbjct: 97 AKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAAR 156 Query: 446 RIQ--AKIQSITHSLLSMEQKLGVSDAAKTQFDQAYKLITSIVGEVERQNAWSAAKSALR 503 + ++ + + K+ +A K + + + + +AK Sbjct: 157 KADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTL 216 Query: 504 EWSSHRHQADRVHPIRMQLAELEQRLQQRNNAERQLAEFNKQYGKNVEP-DDLFTLQEEL 562 E + A R + L ++ + +L E Sbjct: 217 E-AEKAALAARKADLEKALEGAMNFSTA---DSAKIKTLEAEKAALEARQAELEKALEGA 272 Query: 563 EAKIEELSDYVSDSGEQRMQMRQELDQLKQQIEKL---RKQAPVWFAAQDALTQLCEQTH 619 S + ++ + E L+ Q + L R+ A + E H Sbjct: 273 MNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEH 332 Query: 620 QSFETSNQVTEYMQQLLEKEREATVLRDETAARKQQIEAQIERL 663 Q E N+++E +Q L ++ +A + K+Q+EA+ ++L Sbjct: 333 QKLEEQNKISEASRQSLRRDLDA------SREAKKQLEAEHQKL 370 Score = 38.9 bits (90), Expect = 1e-04 Identities = 74/402 (18%), Positives = 156/402 (38%), Gaps = 24/402 (5%) Query: 272 ADYMRHANERRVHLDQALSLRKELWDQRKAINNEAYRFIEMGKELEEQQALSADLETDYQ 331 +D + + H D+ L +EL + ++ + E +++E +A ADLE + Sbjct: 74 SDLSFNNKALKDHNDE---LTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALE 130 Query: 332 AASDRLNLVQNAVRQQEK-IDRYVADVEEITFRLEEQSEVVEEATSKKEELEARVGSAEE 390 A + ++ E A ++ LE ++K + LEA + E Sbjct: 131 GAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEA 190 Query: 391 EVDELKSQLADYQQALDVQQTRAIQYRQAVQALERAKAQCGIDDLDETNAELWAERIQAK 450 EL+ L + AL KA + A ++ AK Sbjct: 191 RQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADL---EKALEGAMNFSTADSAK 247 Query: 451 IQSITHSLLSMEQKLGVSDAAKTQFDQAYKLITSIVGEVERQNAWSAAKSALREWSSHRH 510 I+++ ++E + + A ++ + +E + A A+ A E S Sbjct: 248 IKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVL 307 Query: 511 QADR------VHPIRMQLAELEQRLQQRNNAERQLAEFNKQYGKNVEPDDLFTLQEELEA 564 A+R + R +LE Q+ + +++E ++Q + D +++LEA Sbjct: 308 NANRQSLRRDLDASREAKKQLEAEHQKLEE-QNKISEASRQ-SLRRDLDASREAKKQLEA 365 Query: 565 KIEELSDYVSDSGEQRMQMRQELDQLKQQIEKLRKQAPVWFAAQDALTQLCEQTHQSFET 624 + ++L + S R +R++LD ++ +++ K + AL +L ++ +S + Sbjct: 366 EHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKL 425 Query: 625 SNQVTEYMQQLLEKEREATVLRDETAARKQQIEAQIERLSQP 666 + + +Q LE E +A K+++ Q E L++ Sbjct: 426 TEKEKAELQAKLEAEAKAL---------KEKLAKQAEELAKL 458 Score = 31.2 bits (70), Expect = 0.040 Identities = 33/270 (12%), Positives = 79/270 (29%), Gaps = 26/270 (9%) Query: 980 SENNDLNEKLRRRLEMAETERATARELYRQQQAQCDQFNQVLASLKSSFDTKSEL---LR 1036 + + + L ++ + L+ + + SE ++ Sbjct: 57 ERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQ 116 Query: 1037 ELEQEMKETGLQIDAGAEARAKELRDQRY--AAVSANRTRISQLERDIALSEAERENMAK 1094 ELE + ++ + + A +A R + LE+ + + + Sbjct: 117 ELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSA 176 Query: 1095 KIRKLERDYGQMREHVVSAKASWCAVMRLVKENGMERRLHRRDFAYLSADELRSMSDKAL 1154 KI+ LE + + ++ +E+ L + + Sbjct: 177 KIKTLEAEKAALEA----------------RQAELEKALEGAMNFSTADSAKIKTLEAEK 220 Query: 1155 GALRQAVADNEYLRDALRRSEDAKYPD-RKVQFFIAVYQH----LRERIRQDIIKTDDPV 1209 AL AD E + A + ++ A + L + + + + Sbjct: 221 AALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADS 280 Query: 1210 DAIEQMEIELARLTEELTSREQKLAISSRS 1239 I+ +E E A L E E + + + + Sbjct: 281 AKIKTLEAEKAALEAEKADLEHQSQVLNAN 310
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.5 bits (84), Expect = 2e-05 Identities = 17/85 (20%), Positives = 33/85 (38%), Gaps = 5/85 (5%) Query: 65 AVIDGQIVGVVGLELCTKPNGTHRGEICKLLVSPDHRHKGIAQQLMQKAEQIAWERGITL 124 ++ +G + + + N I + V+ D+R KG+ L+ KA + A E Sbjct: 70 YYLENNCIGRIKI----RSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCG 125 Query: 125 LTLDTITKGM-TVSLYRFLGWQVSG 148 L L+T + Y + + Sbjct: 126 LMLETQDINISACHFYAKHHFIIGA 150
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 29.4 bits (66), Expect = 0.019 Identities = 19/78 (24%), Positives = 33/78 (42%), Gaps = 15/78 (19%) Query: 131 YPEIKKLLSSDVVNMQQQALFDPDGLKTWIIENITADWLM----DFILNYSADVDL---- 182 Y +IK+ LS+++V Q+ L+ P+ T E+ D ++ D + Y + L Sbjct: 141 YQDIKEKLSAEIVIKQKVELY-PNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALE 199 Query: 183 ------ALYQENKFFPVY 194 + FPVY Sbjct: 200 LEQEESIRFHNCSLFPVY 217
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 25.2 bits (55), Expect = 0.029 Identities = 8/28 (28%), Positives = 12/28 (42%), Gaps = 1/28 (3%) Query: 8 TAIKKACNYVGG-QSEMAKRLGISPPTV 34 I A G Q + A LG++ T+ Sbjct: 439 PLILAALTATRGNQIKAADLLGLNRNTL 466
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 27.1 bits (60), Expect = 0.003 Identities = 9/49 (18%), Positives = 23/49 (46%) Query: 12 LQFFTIGRPFAGIFCLILQITLIGWIPAAIWSVYALSQYNTDKKIEKMS 60 ++ A + + + L+G +PAA+W ++ +++ D +S Sbjct: 203 FRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGIS 251
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 37.1 bits (86), Expect = 4e-04 Identities = 20/161 (12%), Positives = 49/161 (30%), Gaps = 20/161 (12%) Query: 721 QARAEADKAEAQQRQFLATQLR--GDYTGNDLSKVTAGLISAEKQARVTGDQAEAKARQS 778 A A+ K ++ Q Q R +L+K+ + E + ++ + Sbjct: 131 GAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSL 190 Query: 779 LETR----------MNGNVSVINKSLGTLTSKQQAQTQEISTLNSNL--------KGKAD 820 ++ + N+ T+ ++ S L K Sbjct: 191 IKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIA 250 Query: 821 SSAVNALNTRVSNIDGKMTATAQQVTRLESQVGSSSAKIEQ 861 AV + ++ Q+ ++ES++ S+ + + Sbjct: 251 KHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQL 291
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 33.2 bits (76), Expect = 0.001 Identities = 24/130 (18%), Positives = 46/130 (35%), Gaps = 35/130 (26%) Query: 2 IAITGATGLLGQHVIENLLQTVPANQIVAF---------ARDVKKGSSLSQKGVLVRQAD 52 +TGA G +G HV + LL+ +Q+V + + L+Q G + D Sbjct: 3 YLVTGAAGFIGFHVSKRLLEA--GHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 53 YNDKASL--ITALQGVDKLL-----------------LISSSEVGKRTIQHRNVIEAAKS 93 D+ + + A +++ S+ G N++E + Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTG-----FLNILEGCRH 115 Query: 94 ADVQFIAYTS 103 +Q + Y S Sbjct: 116 NKIQHLLYAS 125
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 378 bits (971), Expect = e-120 Identities = 191/850 (22%), Positives = 342/850 (40%), Gaps = 88/850 (10%) Query: 2 RLKSINAFVLSLLVSPFYVCA--------DLNMDFLHGGVQLQA-AGVFDENTNYPAGHY 52 R + F + L V+ + N FL Q A F+ P G Y Sbjct: 19 RKHRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTY 78 Query: 53 IVEVIFNRKLISKKELIISPEDNEN---LCLKKDWINELSLPIKLNLFELYYHPERDCYD 109 V++ N ++ +++ + D+E CL + + + L + + + C Sbjct: 79 RVDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTAS-VSGMNLLADDACVP 137 Query: 110 I-SRYPGAQVIFDNSKQTLTFSIPQIALDESLRR----QEWDYGITGIKLNYSGYISKTS 164 + S A D +Q L +IPQ + R + WD GI LNY+ + Sbjct: 138 LTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQ 197 Query: 165 SSQA----QIYGDFDLYANLGRWVAYVRSSYQRNSGT---------ETSEATVSTAIKSI 211 + Y + N+G W +++ NS + + I + Sbjct: 198 NRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPL 257 Query: 212 QGSFTVGKTITSLSILPNFAFYGMSLRSERDMRPWEKRGYAPVISGVANSNAKITISQNG 271 + T+G T I F G L S+ +M P +RG+APVI G+A A++TI QNG Sbjct: 258 RSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNG 317 Query: 272 YVLSSQVVPAGAYQLKNIAPVS-NGNITVTVEESDGTKTVRYYPVATLSSLLRTDEINYN 330 Y + + VP G + + +I +G++ VT++E+DG+ + P +++ L R Y+ Sbjct: 318 YDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYS 377 Query: 331 IAIGE-KETVGKRENSLFFLGAFDYGLTN-VTVHAAGILHNNYKSAALGMSKDFGRFGAM 388 I GE + ++E FF +GL T++ L + Y++ G+ K+ G GA+ Sbjct: 378 ITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGAL 437 Query: 389 SFTANTAVSVFQKQTPTAPEVRQSGISYSLQYANSLTD-NTNLQLLAYRYTGKDYVDFNE 447 S A S + + G S Y SL + TN+QL+ YRY+ Y +F + Sbjct: 438 SVDMTQANSTLPDDS------QHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFAD 491 Query: 448 F----------------------NSNALYHRSNRKERYETILSQSF-DGSFVSLSAWMQT 484 ++ N++ + + ++Q S + LS QT Sbjct: 492 TTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQT 551 Query: 485 YRNSISNEVGANITYNTTIKSVDFSLSADYQK-LNDYEHDNYIISVGINIPFS---LYDK 540 Y + + + NT + ++++LS K D ++++ +NIPFS D Sbjct: 552 YWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQ-MLALNVNIPFSHWLRSDS 610 Query: 541 NHFWAN-----SVSYDRKNKASFNSGVSGSINE--KINYSINTSKDRDNWSNSAYFGIDH 593 W + S+S+D + + +GV G++ E ++YS+ T NS G Sbjct: 611 KSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYAT 670 Query: 594 SIINTGYA-----ISQNGHQTTSSINASGSLLATPDTGLLFSNVRRDTVAIAKIKNIEGI 648 GY S + SG +LA + G+ DTV + K + Sbjct: 671 LNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHAN-GVTLGQPLNDTVVLVKAPGAKDA 729 Query: 649 TFNDSPP--TDKEGNTIV-GVSPYIENNLKINTEEIPNNVELLDSVQNFTPADKAIIYRE 705 + TD G ++ + Y EN + ++T + +NV+L ++V N P AI+ E Sbjct: 730 KVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAE 789 Query: 706 FKYSTIQRYILRIKNKNGDFISAGSAVRNKNDEYIGFVSNSGVLLLNLLDKPNKLFV--I 763 FK + ++ + N + G+ V +++ + G V+++G + L+ + K+ V Sbjct: 790 FKARVGIKLLMTLT-HNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWG 848 Query: 764 SPNGEKCTLN 773 C N Sbjct: 849 EEENAHCVAN 858
>OMS28PORIN#OMS28 porin signature. Length = 257 Score = 29.4 bits (65), Expect = 0.008 Identities = 21/60 (35%), Positives = 32/60 (53%), Gaps = 5/60 (8%) Query: 21 YVGATSFTSNVTGGTVTSNLSMTVKASCSTTVGDVTFGDQSAGDIKKGAVAE--KVISLA 78 +VG+ S S+V GTV ++ T+ A CS V + G ++ K AV E K +S+A Sbjct: 96 FVGSMSLMSDVAKGTVVASQEATIVAKCSGMVAE---GANKVVEMSKKAVQETQKAVSVA 152
>FIMBRIALPAPF#Escherichia coli: P pili tip fibrillum papF protein signature. Length = 167 Score = 36.6 bits (84), Expect = 2e-05 Identities = 44/159 (27%), Positives = 73/159 (45%), Gaps = 16/159 (10%) Query: 30 ILPDAQLTISLDVVRITCDINNGKGFNKIVDFDVINESNLLAGNQPAVKTQFIVDCQKSG 89 +L D Q+ I +V C INNG+ N +VDF IN ++ K I KSG Sbjct: 17 VLADVQINIRGNVYIPPCTINNGQ--NIVVDFGNINPEHVDNSRGEVTKNISISCPYKSG 74 Query: 90 FKPEHIDIKVKPGSQGALNNGIGGELKTNLS--GVGIYLSWADSSPINL---SGVNKSFS 144 + IKV + G N + L TN++ G+ +Y S+P+ L SG + Sbjct: 75 ----SLWIKVTGNTMGVGQNNV---LATNITHFGIALYQGKGMSTPLTLGNGSGNGYRVT 127 Query: 145 ADLNN-QFDISFFAKPYAQ-SQIVEKGSLKSSIIINALY 181 A L+ + +F + P+ S I+ G +++ ++ +Y Sbjct: 128 AGLDTARSTFTFTSVPFRNGSGILNGGDFRTTASMSMIY 166
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.2 bits (68), Expect = 0.014 Identities = 10/92 (10%), Positives = 34/92 (36%), Gaps = 5/92 (5%) Query: 9 LEALQERYEEIQALLAEADVIASQERFRALSKEYAQLT-DITSCYRQWRKVQDDMEAAEM 67 + R ++ +LL + + ++ +Y + ++ Q +++ ++ +A+ Sbjct: 230 SRVEKSRLDDFSSLLHKQAI--AKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKE 287 Query: 68 MLD--DPEMKEMAQEELKEAQSVNEELEQQLQ 97 K ++L++ L +L Sbjct: 288 EYQLVTQLFKNEILDKLRQTTDNIGLLTLELA 319
>OMS28PORIN#OMS28 porin signature. Length = 257 Score = 31.7 bits (71), Expect = 0.020 Identities = 25/73 (34%), Positives = 36/73 (49%), Gaps = 9/73 (12%) Query: 275 IEGVKEDVKAKYRALGKLIDEEKEKLE--NKWKKSDSDKVEIVTRGGLEIATIAAAFLKV 332 +E VKE + A RAL + + E ++ L N S+ D+V L +A A V Sbjct: 184 VEQVKETLMASERALDETVQEAQKVLNMVNGLNPSNKDQV-------LAKKDVAKAISNV 236 Query: 333 GKVAEGANAINKV 345 KVA+GA + KV Sbjct: 237 VKVAQGARDLTKV 249
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 25.5 bits (55), Expect = 0.046 Identities = 9/38 (23%), Positives = 17/38 (44%) Query: 5 FDNQILDIFGIEQDSFDVDFLQWNYTFSKEGIKLFFVY 42 F + + + S D++F++ N T + L F Y Sbjct: 210 FSQKFKEKLELNNKSIDINFIKENLTEFQHAFSLAFSY 247
>FRAGILYSIN#Fragilysin metallopeptidase (M10C) enterotoxin signature. Length = 405 Score = 31.6 bits (71), Expect = 0.004 Identities = 12/68 (17%), Positives = 27/68 (39%), Gaps = 2/68 (2%) Query: 132 PNYTNIVLLGGSEGATMVHLVVAERHDISAAIALNGGGRFFLDD--VLYNIRNTTPKEHV 189 P ++ L + + V A+ D + ++ G + +++ VLY + P Sbjct: 225 PKTVYVICLRENGSTIYPNEVSAQMQDAANSVYAVHGLKRYVNFHFVLYTTEYSCPSGDA 284 Query: 190 EEAINSFQ 197 +E + F Sbjct: 285 KEGLEGFT 292
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 70.4 bits (172), Expect = 4e-17 Identities = 39/202 (19%), Positives = 73/202 (36%), Gaps = 14/202 (6%) Query: 12 SRQQENSEQTRLALLEAGQYLFVNQCYYDVSIDEISRYARVTKGAFYHHFSNKKALLREC 71 + ++ +++TR +L+ LF Q S+ EI++ A VT+GA Y HF +K L E Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 72 YLLQVKHAVQKLDEVP--TYDDKWQELTALFSLCVDHIYQCKNE----LIPLQEVISVLG 125 + L + + E D L + ++ + I + V Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 126 WKEWEEIDANILIPRIQHCVDIL---FAEKQICA-YSPAIVVNLIYGFIT---HIAINLK 178 ++ N+ + L K + A ++ G+I+ + Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAP 182 Query: 179 NEASLPKEACSDFKAIFADFLI 200 L KEA D+ AI + + Sbjct: 183 QSFDLKKEA-RDYVAILLEMYL 203
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 390 bits (1004), Expect = e-125 Identities = 190/822 (23%), Positives = 345/822 (41%), Gaps = 82/822 (9%) Query: 51 NEHPDGYYSTNIYINENKK-ETIILYYENKDG-ILTPRINVNDLIRLNIDPSFYNIPIDL 108 E P G Y +IY+N + + + P + L + ++ + + L Sbjct: 71 QELPPGTYRVDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLL 130 Query: 109 SSD--LLLSDY--NIDFKYNFSSQSLYLTIPQKALDNKKNMLASQVLWDDGVPALFSSYS 164 + D + L+ + + + Q L LTIPQ + N+ LWD G+ A +Y+ Sbjct: 131 ADDACVPLTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYN 190 Query: 165 YFGKYNNQNKIEHK-----ISFNSGANLGAWRVRSKSYY------HHTHKQQQFKLYSLY 213 + G + QN+I ++ SG N+GAWR+R + + + + +++ + + Sbjct: 191 FSG-NSVQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTW 249 Query: 214 AYHQLNTLLATLNVGEFRPTSRMLSTDKLIGFQLISSNLLSGNDLYMNSPIIEEIAESHA 273 + L + L +G+ + G QL S + + + +P+I IA A Sbjct: 250 LERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTA 309 Query: 274 EIKVKQQGRTIYETIVPPGPFILNDLPVI-GSNELVLEIKEADGRIKKSTHYFTTMPNQL 332 ++ +KQ G IY + VPPGPF +ND+ S +L + IKEADG + T ++++P Sbjct: 310 QVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQ 369 Query: 333 KKGRYQYNFISGYSYDRYNQFNNQNNNPIFLLGEFSYGINQKITAYGAIRKKLNSNTFFS 392 ++G +Y+ +G Y N Q P F +G+ T YG + F Sbjct: 370 REGHTRYSITAG----EYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNF 425 Query: 393 GLSLDLGRWGGVASDISY-------FEHNNLLKYQLRYNKRWSNIGTSLNI-----SSSH 440 G+ ++G G ++ D++ ++ + YNK + GT++ + S+S Sbjct: 426 GIGKNMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSG 485 Query: 441 YQSIKSDSVSIR----------------------KSQTDNIKNSYTISLFQPIKSFGTFS 478 Y + +D+ R + N + +++ Q + T Sbjct: 486 YFNF-ADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLY 544 Query: 479 IGYHQNSY-AKRKNDFTINTSLSSSIKKMNYSIKYQYKNEKY--YNDNHFSLNFNIPLTN 535 + +Y D L+++ + +N+++ Y + D +LN NIP ++ Sbjct: 545 LSGSHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSH 604 Query: 536 SSQSYHWVSNQFDY------HPNNKGYINSTTIGGSLLEHYRLGYSINYRR-DFSHPNAG 588 +S + H N N + G+LLE L YS+ N+G Sbjct: 605 WLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSG 664 Query: 589 YHTSVNTQYKGRYQSYSINTTKSSNNKTNLRLGINGAIVLHQSGVTLAPDLGNTFAIVNT 648 Y+G Y + +I + S + L G++G ++ H +GVTL L +T +V Sbjct: 665 STGYATLNYRGGYGNANIGYSHSDDI-KQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKA 723 Query: 649 NGIAGIKTNRSSQAITDNNGNLILPHIMPYRKNTIGLNINSLP---EFSNTKTQSKIIVP 705 G K + TD G +LP+ YR+N + L+ N+L + N +VP Sbjct: 724 PGAKDAKVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVAN---VVP 780 Query: 706 TLGAVAKINFPINRGYNVLFT---SNTPIPFAANVMAFDDNNNLISSDSVYDHNRIFLSG 762 T GA+ + F G +L T +N P+PF A V +++ V D+ +++LSG Sbjct: 781 TRGAIVRAEFKARVGIKLLMTLTHNNKPLPFGAMV--TSESSQSSG--IVADNGQVYLSG 836 Query: 763 IKESGTVQVKWGDTEEQQCFFHYNVKNESKNNSIIKKQIYCQ 804 + +G VQVKWG+ E C +Y + ES+ + + C+ Sbjct: 837 MPLAGKVQVKWGEEENAHCVANYQLPPESQQQLLTQLSAECR 878
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 419 bits (1079), Expect = e-136 Identities = 200/829 (24%), Positives = 347/829 (41%), Gaps = 76/829 (9%) Query: 31 NGNIDFSLLLNEN-FLEGTYNITIYINNNKKQNSEISFKNKNNN--LTPIITLFDLKQWG 87 D S N GTY + IY+NN +++F ++ + P +T L G Sbjct: 59 QAVADLSRFENGQELPPGTYRVDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMG 118 Query: 88 INTNYYEPLKNKLDNDIVDYDLLKKLFNIKLEINKQSIYFKVPLIAIEKNTS--YSKEKL 145 +NT + D+ V + +L++ +Q + +P + E Sbjct: 119 LNTASVSGMNLLADDACVPLTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELW 178 Query: 146 DDGDNAAFIKYNYQGHYYKQNSLNGQHIHNLQLYNGINLFAWRYRQDLNYNNN------- 198 D G NA + YN+ G+ + H L L +G+N+ AWR R + ++ N Sbjct: 179 DPGINAGLLNYNFSGNSVQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSG 238 Query: 199 --NSFSINQQYVYRTLRNINSILTMGDFYAYSPNLNTYKILGVQINSDNAMKDGSLVGYA 256 N + ++ R + + S LT+GD Y + G Q+ SD+ M S G+A Sbjct: 239 SKNKWQHINTWLERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFA 298 Query: 257 PIISETAYTYAEVSIEQNGETLYSTSVPPGPFTLNNLPSLGTNGELVLIIKEENGEVRKK 316 P+I A A+V+I+QNG +Y+++VPPGPFT+N++ + G +G+L + IKE +G + Sbjct: 299 PVIHGIARGTAQVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIF 358 Query: 317 KIWNYSSQYLLRKNQWNYYYTMGLVNNPQKRQFPSNKKKELLTQLNLSYGVSNYLTTMIG 376 + S L R+ Y T G + R + ++K Q L +G+ T G Sbjct: 359 TVPYSSVPLLQREGHTRYSITAG-----EYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGG 413 Query: 377 AEKKGDDIKALIGNTLGLNILGIVSLENAWIREKYHQQY----QSNKINYQKVFSMENTT 432 + G + LG +S++ QS + Y K + T Sbjct: 414 TQLADRYRAFNFGIGKNMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTN 473 Query: 433 ISL-----NSSFYFRFKENYAVNKEY-------------------------KKYDLGFHF 462 I L ++S YF F + K+ L Sbjct: 474 IQLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTV 533 Query: 463 SQSLNNNIALTLGYNIATYYHSKEKSQRLFINTSSNYKKLSYSLELENSKD--QYSNNNQ 520 +Q L L L + TY+ + ++ ++ ++ ++++L +K+ Q + Sbjct: 534 TQQLGRTSTLYLSGSHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQM 593 Query: 521 LSIFLNYPIGQDLSH---------WATARINYDNREKYFHENISFSGNTLENNRLNYNLD 571 L++ +N P L A+ +++D + + G LE+N L+Y++ Sbjct: 594 LALNVNIPFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNL-AGVYGTLLEDNNLSYSVQ 652 Query: 572 FSKNNKERLDS----SMKINYLSRIAKLNINSRFNKDSYSLGYGLNGGIVFHNGGITLAQ 627 +S +NY NI + D L YG++GG++ H G+TL Q Sbjct: 653 TGYAGGGDGNSGSTGYATLNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQ 712 Query: 628 DLNDSFAILNFAGAKKVKIIGKPTIESDRRGYLIIPNLTSYHNNKFHIDAKSLDYNYNID 687 LND+ ++ GAK K+ + + +D RGY ++P T Y N+ +D +L N ++D Sbjct: 713 PLNDTVVLVKAPGAKDAKVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLD 772 Query: 688 NYSYHLIPTKGAIIAKNIKVTKGESALFTFHQN---IPFGATAYVKNSDGTLSDISYVNE 744 N +++PT+GAI+ K G L T N +PFGA V + V + Sbjct: 773 NAVANVVPTRGAIVRAEFKARVGIKLLMTLTHNNKPLPFGAM--VTSESSQ--SSGIVAD 828 Query: 745 DNKLYISNLPISGKIFVKWGSSNKQQCSFNYQLNDNEKQNRIYFKTVNC 793 + ++Y+S +P++GK+ VKWG C NYQL +Q + + C Sbjct: 829 NGQVYLSGMPLAGKVQVKWGEEENAHCVANYQLPPESQQQLLTQLSAEC 877
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 31.5 bits (71), Expect = 0.002 Identities = 13/61 (21%), Positives = 23/61 (37%), Gaps = 3/61 (4%) Query: 184 DKLARFDDIGTDIAYQGNGYATHLITHVLEFCREQGVERCFLDASADGLA---LYRKFGF 240 + A +DI Y+ G T L+ +E+ +E L+ ++ Y K F Sbjct: 87 NGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146 Query: 241 K 241 Sbjct: 147 I 147
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 32.0 bits (72), Expect = 0.007 Identities = 19/46 (41%), Positives = 27/46 (58%), Gaps = 4/46 (8%) Query: 535 ELLMKLIALEDKLNADLARK---SAHQKPILQAQWQAEIEILKQQL 577 E KL ALE KLN +L + +K LQA+ +AE + LK++L Sbjct: 404 EANSKLAALE-KLNKELEESKKLTEKEKAELQAKLEAEAKALKEKL 448
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 47.9 bits (114), Expect = 4e-08 Identities = 37/239 (15%), Positives = 77/239 (32%), Gaps = 11/239 (4%) Query: 4 KKSRSTTALLFSSLILTIGRGATLPFMAIYLSRQYKLPVD---DIGIAMSISLTTGIVFS 60 K +R +L + + +G G +P + L R D GI +++ + Sbjct: 2 KPNRPLIVILSTVALDAVGIGLIMPVLPGLL-RDLVHSNDVTAHYGILLALYALMQFACA 60 Query: 61 LAFGMLADKFEKKRYMVFSIITFIIAFSAIPMVNSTILVVIFFS-IINCSYLVFSTVLKA 119 G L+D+F ++ ++ S+ A M + L V++ I+ V A Sbjct: 61 PVLGALSDRFGRRPVLLVSLAGA--AVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGA 118 Query: 120 YFSETLSISAKPKIFSLNYTFINIGWTVGPPIGTLLLMYGTQLPFWLAAISASIPLFMIQ 179 Y ++ + + F G GP +G L+ + PF+ AA + Sbjct: 119 YIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGC 178 Query: 180 CFVQRSVVEHSTEENSVKWDPKIMLKDKALGWFVLSTFFGTLTFGTFASCISQYLLVVY 238 + S +P + ++ + + Q ++ Sbjct: 179 FLLPESHKGERRPLRREALNPLASFRWA----RGMTVVAALMAVFFIMQLVGQVPAALW 233
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 140 bits (355), Expect = 9e-39 Identities = 95/413 (23%), Positives = 178/413 (43%), Gaps = 15/413 (3%) Query: 13 ICLGTFMATLDISIVNVALPTIQNDINANMATLQWIVDAYALCLSACILSSGPLSDRFGR 72 +C+ +F + L+ ++NV+LP I ND N A+ W+ A+ L S G LSD+ G Sbjct: 19 LCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGI 78 Query: 73 KKVWLWGVIIFTLGSLICAIAQQH-EILILGRIIQGIAAAALIPGALSLITHAFPVDIER 131 K++ L+G+II GS+I + +LI+ R IQG AAA P + ++ + R Sbjct: 79 KRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAA-FPALVMVVVARYIPKENR 137 Query: 132 IRIIGIWSSVSALSLIIGPILGGALVHASGWASIFLINIPIGAITVLLGWYGLSESADPE 191 + G+ S+ A+ +GP +GG + H W+ +L+ IP+ I + L + Sbjct: 138 GKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKEVRI 195 Query: 192 DVALDPLGQLTSILGLGLLTYGFIEAGSVGWSDYRTVFALIVGLIFITLFVIVEKRIERP 251 D G + +G+ S S LIV ++ +FV +++ P Sbjct: 196 KGHFDIKGIILMSVGIVFFMLF---TTSYSIS------FLIVSVLSFLIFVKHIRKVTDP 246 Query: 252 LLPLSLFKDRSFFQYNLSSFTLGFATYSNVFFIAFFLQKAQGWSALETG-LRMAPEFIAM 310 + L K+ F L + V + + ++ S E G + + P +++ Sbjct: 247 FVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSV 306 Query: 311 ALFSMLFGRFSRYISVRKLMIFGFLLIAISSCLLATLATNSSYTITGSYLFILGAGMGLA 370 +F + G ++ G +++S + L +S+ +T +F+LG Sbjct: 307 IIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTK 366 Query: 371 TPAIGVLVMKSVAPSRSGMASATMNALRQTGMTMGIALLGTLMIQQAINYMMI 423 T I +V S+ +G + +N GIA++G L+ ++ ++ Sbjct: 367 T-VISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLDQRLL 418
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 67.0 bits (163), Expect = 6e-16 Identities = 17/77 (22%), Positives = 37/77 (48%) Query: 10 KPRTKPAEVRLEELMNAAETLFLEKGFDATTVSDIVKQAGVAKGTYYHYFTAKTDILDAL 69 + + A+ + +++ A LF ++G +T++ +I K AGV +G Y +F K+D+ + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 70 RTRYMDWYIDKVEQAMA 86 + + A Sbjct: 63 WELSESNIGELELEYQA 79
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 30.5 bits (69), Expect = 0.015 Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 23/82 (28%) Query: 366 TIGSAKALHMEDKLGSLESGKLADIIVVDTK----APNMV---------PMYSPYAAL-- 410 TI A A + ++GSLE GK AD+++ + P+MV PM P A++ Sbjct: 410 TINPAIAHGLSHEIGSLEVGKRADLVLWNPAFFGVKPDMVLLGGTIAAAPMGDPNASIPT 469 Query: 411 --------VYGANGSNVRHTIV 424 ++GA G + ++ V Sbjct: 470 PQPVHYRPMFGAYGRSRTNSSV 491
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 61.8 bits (150), Expect = 1e-12 Identities = 73/351 (20%), Positives = 131/351 (37%), Gaps = 21/351 (5%) Query: 10 FLVLIYPLGVDLYLTGLTAIASDLNASEVTLHHAFSIYLMGMVSSMLIAGWCSDNLGRKP 69 L L + L IA+D N + + + +++ + G SD LG K Sbjct: 21 ILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKR 80 Query: 70 VILFGTLIFFLASLSAGLSITEKQFLI-SRFFQGSGSGFCYVVTFAILRDTLTEQQRAKV 128 ++LFG +I S+ + + LI +RF QG+G+ + ++ + ++ R K Sbjct: 81 LLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKA 140 Query: 129 LSMINGITCIIPVLAPVLGFIILLYCEWSMMFYLMGAYSLLVFIFCFLGIKETYHKKEIK 188 +I I + + P +G +I Y WS + + + V L KE K Sbjct: 141 FGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFD 200 Query: 189 IKK-VNLSVIKPTTESFLTHYFLSRLLISCLGMAVILTYVN--ISPIVVMQQMNYSTGEY 245 IK + +SV F T Y +S L++S L + + ++ P V Sbjct: 201 IKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMI 260 Query: 246 SILMTSLAMISMTISFLMPKILMKYRYKHILSVGLICFGIGIIFLFIGKKSDMRWFFITF 305 +L + ++ M +MK + L IG + +F G S + + +I Sbjct: 261 GVLCGGIIFGTVAGFVSMVPYMMKDVH------QLSTAEIGSVIIFPGTMSVIIFGYIGG 314 Query: 306 ALCGSGFALLFGIIMSQALSPFSQRAGVASSVLGISQLSFSSLYIWVMGWI 356 L L+ + + + S L S L ++ W M I Sbjct: 315 ILVDR-RGPLYVLNIGVTFL--------SVSFLTASFLLETT--SWFMTII 354
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 28.0 bits (62), Expect = 0.012 Identities = 9/20 (45%), Positives = 12/20 (60%) Query: 78 VVVAHKYRGKGVAASLIKMA 97 + VA YR KGV +L+ A Sbjct: 95 IAVAKDYRKKGVGTALLHKA 114
>ENTEROVIROMP#Enterobacterial virulence outer membrane protein signature. Length = 171 Score = 134 bits (339), Expect = 1e-42 Identities = 58/177 (32%), Positives = 91/177 (51%), Gaps = 10/177 (5%) Query: 4 NFLLSTSILVVSTLSFNAYATLENTVSIGYAKSKLKVDEDLINDNLKGINLKYNHEVAND 63 +++ V + +TV+ GYA+S + + + G NLKY +E N Sbjct: 3 KIACLSALAAVLAFTAGTSVAATSTVTGGYAQSDAQGQMN----KMGGFNLKYRYEEDNS 58 Query: 64 -WGVISSFSYAKNKNDGYDHWGYAGTSKISYYSLTAGPSYRLNNYVSAYGLIGFGYFHED 122 GVI SF+Y + +K YY +TAGP+YR+N++ S YG++G GY Sbjct: 59 PLGVIGSFTYTEKSRTASS----GDYNKNQYYGITAGPAYRINDWASIYGVVGVGYGKFQ 114 Query: 123 FHYYDE-REKENKISMAYGLGVQVNPITNLAIDVSYEYSKLYDIDFTTWVVGIGYRF 178 Y + + +YG G+Q NP+ N+A+D SYE S++ +D TW+ G+GYRF Sbjct: 115 TTEYPTYKHDTSDYGFSYGAGLQFNPMENVALDFSYEQSRIRSVDVGTWIAGVGYRF 171
>ENTEROVIROMP#Enterobacterial virulence outer membrane protein signature. Length = 171 Score = 51.4 bits (123), Expect = 1e-10 Identities = 30/169 (17%), Positives = 59/169 (34%), Gaps = 21/169 (12%) Query: 21 AFENNQAIYGGYIYGKIKNH--KANGAIISYHYGSDIH-WGMLLSLLHIKSTHQSHFIDA 77 + + GGY + K G + Y Y D G++ S + + + + Sbjct: 21 SVAATSTVTGGYAQSDAQGQMNKMGGFNLKYRYEEDNSPLGVIGSFTYTEKSRTAS---- 76 Query: 78 SSLKLGTKDEHAKVSALLIGPTYRITPSLAIYAQMGPKKLKYRVDKSYSGVAVTDTIIVD 137 + + GP YRI +IY +G K++ Y + Sbjct: 77 -----SGDYNKNQYYGITAGPAYRINDWASIYGVVGVGYGKFQ-TTEYPTYKHDTS---- 126 Query: 138 TTNVMFQAGIDYSLRKNVGINLGYLHSDTESNKHNIRLNSIQLSLGYRF 186 + AG+ ++ +NV ++ Y S ++ + + +GYRF Sbjct: 127 DYGFSYGAGLQFNPMENVALDFSYEQ----SRIRSVDVGTWIAGVGYRF 171
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 30.1 bits (67), Expect = 0.030 Identities = 47/251 (18%), Positives = 82/251 (32%), Gaps = 35/251 (13%) Query: 158 GVEAIDEKTLKVTLERPVPYFPSLATNFSLYPVPKHTIEKYGSEWIKVGNLVGNGAFILK 217 G + K +KV ++PV N S P + EK I N++ G + Sbjct: 844 GGINTESKKIKVVEDKPVE-----VINES---EPNNDFEKANQ--IAKSNMLVKGTLSEE 893 Query: 218 DRVVNEKIVLTPNPYYWDHHNTVLTKVTFVPINHESQATKRYLAGDID--ITESFPKHLY 275 D + YY+D K+T +N Y GD++ + + Sbjct: 894 DYS---------DKYYFDVAKKGNVKITLNNLNSVGITWTLYKEGDLNNYVLYATGNDGT 944 Query: 276 HKLMKDIPDQVYIPEQLGTYYYAFNTQAGPTKDIRVRKALAMAID---RKIITDKVLGTG 332 ++ P + Y ++ Q+G T + V+ L + + I + Sbjct: 945 VLK----GEKTLEPGRYYLSVYTYDNQSG-TYTVNVKGNLKNEVKETAKDAIKEVENNND 999 Query: 333 EKSANRFTPDVTANFTPEPT-LYDEYSQDELD-SQAKILLSAAGYGPHNPLTLSLLYNNS 390 A + + T L D YS D + S I++ N LLY+ Sbjct: 1000 FDKAMKVDSNSKIVGTLSNDDLKDIYSIDIQNPSDLNIVVENLDNIKMN----WLLYSAD 1055 Query: 391 ENHQKIAIAVA 401 + + A A Sbjct: 1056 DLSNYVDYANA 1066
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 325 bits (834), Expect = e-108 Identities = 111/352 (31%), Positives = 172/352 (48%), Gaps = 32/352 (9%) Query: 198 DNSGFEQVIAVSTPMKQLVERAKKMAKMDDPLLLVGDTGTGKDLFAKACHLLSPRAREPF 257 D+ ++ S M+++ ++ + D L++ G++GTGK+L A+A H R PF Sbjct: 132 DSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPF 191 Query: 258 LGLNCASMPDDVVESELFGYAAGAYPNAIEGKKGFFEQANRGTVLLDEIGEMSPQMQIKL 317 + +N A++P D++ESELFG+ GA+ A G FEQA GT+ LDEIG+M Q +L Sbjct: 192 VAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRL 251 Query: 318 LRFLNDGTFRRVGEEHEVKVDVRIICATQKNLWELVQKGLFREDLYYRLNVLTLTLPPLR 377 LR L G + VG ++ DVRI+ AT K+L + + +GLFREDLYYRLNV+ L LPPLR Sbjct: 252 LRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLR 311 Query: 378 ERKADIMPLALHFINQYCLEQKASKPVISPDLSAYLVQYGWPGNVRQLRNTIYQAMAQLV 437 +R DI L HF+ Q E K + + + WPGNVR+L N + + A Sbjct: 312 DRAEDIPDLVRHFVQQAEKEGLDVK-RFDQEALELMKAHPWPGNVRELENLVRRLTALYP 370 Query: 438 GNTLRPQDI---------------------------ALPEHTADTL---FDEDLLEGSLD 467 + + + I A+ E+ D G D Sbjct: 371 QDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYD 430 Query: 468 EMTKRFEASILRR-LYRDYPSTRKLAKRLGISHTAIANKLREYDLTSKKADK 518 + E ++ L + K A LG++ + K+RE ++ ++ + Sbjct: 431 RVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVSVYRSSR 482
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 58.1 bits (140), Expect = 1e-12 Identities = 32/183 (17%), Positives = 63/183 (34%), Gaps = 14/183 (7%) Query: 10 RKQQLIQATLAVINEVGMQDASIALIARKAGVSNGIISHYFRDKNGLLEAAMRHIQYQLG 69 +Q ++ L + ++ G+ S+ IA+ AGV+ G I +F+DK+ L + +G Sbjct: 12 TRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIG 71 Query: 70 FAVAMRL-RILSDAEPKLRIQAIVDGNFDTSQTSETAMKTWLAFWASSMHQ----PNLHR 124 + D LR I+ +++ T E + + + + Sbjct: 72 ELELEYQAKFPGDPLSVLR--EILIHVLESTVT-EERRRLLMEIIFHKCEFVGEMAVVQQ 128 Query: 125 LQKVNDRRLYSNLCYEFGRALTKDK------ARLAAKGLAALIDGLWLRSALSEEPFSLA 178 Q+ Y + + R AA + I GL + + F L Sbjct: 129 AQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLK 188 Query: 179 EAK 181 + Sbjct: 189 KEA 191
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 817 bits (2111), Expect = 0.0 Identities = 371/844 (43%), Positives = 547/844 (64%), Gaps = 20/844 (2%) Query: 29 FNPNLISNIDNEVADLSRFDKGEGQPEGMYSVEIYVNDEYVETKNLIFYESDASSDDTGL 88 FNP +++ VADLSRF+ G+ P G Y V+IY+N+ Y+ T+++ F D + G+ Sbjct: 49 FNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGYMATRDVTFNTGD---SEQGI 105 Query: 89 LPCIDNKTLTNFGITLTENSKKKSEEVESKDSACENILDKIENSSVKFDFEGQKLFLSIP 148 +PC+ L + G+ S D AC + I +++ + D Q+L L+IP Sbjct: 106 VPCLTRAQLASMGLNTASVSGMNLLA----DDACVPLTSMIHDATAQLDVGQQRLNLTIP 161 Query: 149 QIMFKNNVRGFIPPEKWDNGINAFLLNYNFTGRNSKNFKDNVDNNNYFLNLNPGINLGSW 208 Q N RG+IPPE WD GINA LLNYNF+G + +N + +++ +LNL G+N+G+W Sbjct: 162 QAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQN-RIGGNSHYAYLNLQSGLNIGAW 220 Query: 209 RFRNESSWNYASGES---KQNKWRNIRTYVQKPIIPLRAELTLGDSFSNGTIFDSLGFRG 265 R R+ ++W+Y S +S +NKW++I T++++ IIPLR+ LTLGD ++ G IFD + FRG Sbjct: 221 RLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTLGDGYTQGDIFDGINFRG 280 Query: 266 IKLESDDNMLPDSMRGFAPTIKGIANSNAIVTVKQNGFVIYQISVPPGAFEIKDLYATSS 325 +L SDDNMLPDS RGFAP I GIA A VT+KQNG+ IY +VPPG F I D+YA + Sbjct: 281 AQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPPGPFTINDIYAAGN 340 Query: 326 SGNLDVTIKENNGKITQFVVPYSNVPILQREGRLKYELIGGEFRSGADYQDKPNFGQLSL 385 SG+L VTIKE +G F VPYS+VP+LQREG +Y + GE+RSG Q+KP F Q +L Sbjct: 341 SGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYRSGNAQQEKPRFFQSTL 400 Query: 386 VYGLPYNMTLYGGSQFSNNYQAYAIGLGGNLGTFGAISADVIQANSILPNDEHKKGQSFR 445 ++GLP T+YGG+Q ++ Y+A+ G+G N+G GA+S D+ QANS LP+D GQS R Sbjct: 401 LHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQANSTLPDDSQHDGQSVR 460 Query: 446 LLYAKSINSTGTNFQIMGYRYSTQGYYTLNEVSYKKMAGREIVTDNGIIRDEDNLSNYYN 505 LY KS+N +GTN Q++GYRYST GY+ + +Y +M G I T +G+I+ + ++YYN Sbjct: 461 FLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYN 520 Query: 506 LNYSKKGRFQLNINQQITNNSSLYILGSYQNYWRTTETEQLWQLGYNANIDRINYSLSLS 565 L Y+K+G+ QL + QQ+ S+LY+ GS+Q YW T+ ++ +Q G N + IN++LS S Sbjct: 521 LAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYS 580 Query: 566 KLKSPGMRGDNKNVAFNISIPLNDVFNQQTVSDLHSSRNSMYAVYSMNRSDDNVWVNQVG 625 K+ +G ++ +A N++IP + SD S A YSM+ + N G Sbjct: 581 LTKNAWQKGRDQMLALNVNIPFSH----WLRSDSKSQWRHASASYSMSHDLNGRMTNLAG 636 Query: 626 LTGTLLEDNNLNYNIQQGYTHNG---SGYSGMVYANYKGKYANIGSGYNYSNDWHEFNYS 682 + GTLLEDNNL+Y++Q GY G SG +G NY+G Y N GY++S+D + Y Sbjct: 637 VYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIGYSHSDDIKQLYYG 696 Query: 683 LNGGIVAHAGGITLTQPLGDTNILIKANDANNIKVENANGILTDNNGYAVLPFASTYKNN 742 ++GG++AHA G+TL QPL DT +L+KA A + KVEN G+ TD GYAVLP+A+ Y+ N Sbjct: 697 VSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTDWRGYAVLPYATEYREN 756 Query: 743 RVSLDVNSLEENIELENTIINVVPTKGALVEANFKTNIGYRAMVTLSKKDGAIIPFGAMV 802 RV+LD N+L +N++L+N + NVVPT+GA+V A FK +G + ++TL + +PFGAMV Sbjct: 757 RVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKLLMTL-THNNKPLPFGAMV 815 Query: 803 VDEERSVSGIVGDNGNVFISGLAPVGRLKAKWGKMADQQCIFDYQINEKSSKEKGIYFIS 862 E SGIV DNG V++SG+ G+++ KWG+ + C+ +YQ+ + S+++ + +S Sbjct: 816 TSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCVANYQLPPE-SQQQLLTQLS 874 Query: 863 STCQ 866 + C+ Sbjct: 875 AECR 878
>FRAGILYSIN#Fragilysin metallopeptidase (M10C) enterotoxin signature. Length = 405 Score = 28.1 bits (62), Expect = 0.006 Identities = 13/31 (41%), Positives = 16/31 (51%) Query: 4 KMKATCFLLMLTSFALLTGCSQSKQAQNTTA 34 KMK LLML + ALL CS + T+ Sbjct: 8 KMKNVKLLLMLGTAALLAACSNEADSLTTSI 38
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 53.7 bits (129), Expect = 7e-10 Identities = 42/212 (19%), Positives = 84/212 (39%), Gaps = 3/212 (1%) Query: 21 VIILSFAAFVFNTTEFVPVALLSNISESFAMVPAQTGLMITIYAWVVALMSLPLMIMTSK 80 +I L +F E V L +I+ F PA T + T + ++ + ++ + Sbjct: 16 LIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQ 75 Query: 81 VERRKLLIILFIVFILSHVLSGVAWDFNS-LIVGRVGVAFAHAVFWSITASLAIRMAPHG 139 + ++LL+ I+ V+ V F S LI+ R A F ++ + R P Sbjct: 76 LGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKE 135 Query: 140 KKAQALSLLATGVALATVLGLPLGRVVGQWLGWRATFLGIGVLALITMLALMRYLPLLPS 199 + +A L+ + VA+ +G +G ++ ++ W ++L + + I + + L Sbjct: 136 NRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHW--SYLLLIPMITIITVPFLMKLLKKEV 193 Query: 200 EHSGSLKSVPILLKRAPLVGIFLLTVIAVTAH 231 G I+L +V L T + Sbjct: 194 RIKGHFDIKGIILMSVGIVFFMLFTTSYSISF 225
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 31.1 bits (70), Expect = 0.008 Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 6/79 (7%) Query: 109 KQVAELTGI----NVVASSGLYIEKF-EGKRLADDIDAMAKMIDDELNIGIDGTDIRAGM 163 + EL G+ + S YI+ + EGKRL D K + D L ID +D ++ Sbjct: 482 TLIGELAGVTRNGDKTLSGKSYIDYYEEGKRLEKKXDEFQKQVFDPLKGNIDLSDSKSST 541 Query: 164 IGEIGVSPFFTDGEKNSLR 182 + + V+P T GE+ R Sbjct: 542 LLKF-VTPLLTPGEEIRER 559
>FLAGELLIN#Flagellin signature. Length = 507 Score = 172 bits (438), Expect = 2e-51 Identities = 148/335 (44%), Positives = 190/335 (56%), Gaps = 4/335 (1%) Query: 2 AQVINTNYLSLVTQNNLNRSQSALGNAIERLSSGMRINSAKDDAAGQAIANRFTSNINGL 61 AQVINTN LSL+TQNNLN+SQS+L +AIERLSSG+RINSAKDDAAGQAIANRFTSNI GL Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 TQASRNANDGISVSQTTEGALNEINNNLQRIRELTVQAKNGTNSNSDITSIQNEVNQRLD 121 TQASRNANDGIS++QTTEGALNEINNNLQR+REL+VQA NGTNS+SD+ SIQ+E+ QRL+ Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 EINRVSEQTQFNGVKVLSGEKSKMTIQVGTNDNEVIEFNLDKIDNDTLGVASDNLFDAKT 181 EI+RVS QTQFNGVKVLS ++M IQVG ND E I +L KID +LG+ N+ K Sbjct: 121 EIDRVSNQTQFNGVKVLSQ-DNQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKE 179 Query: 182 EKKGVKATGDAIDAN---ALGISGGTKYATGVSVKEYKVDGKVSANKVVLKDGSDEYVVS 238 G + + + +KV + + + Sbjct: 180 ATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTD 239 Query: 239 KSDFTLKSGTTTGEIEFTGSKTIKFKADAGKDVKVLNVKDDALATLDNAISKVDESRSKL 298 ++ G+ K A A K K + D T ++ K+ Sbjct: 240 DAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGNGKV 299 Query: 299 GAIQNRFQSTINNLNNTVNNLSASRSRILDADYAT 333 N + T+ + T + + + + Sbjct: 300 STTINGEKVTLTVADITAGAANVDAATLQSSKNVY 334 Score = 112 bits (282), Expect = 1e-29 Identities = 91/235 (38%), Positives = 110/235 (46%), Gaps = 13/235 (5%) Query: 146 TIQVGTNDNEVIEFNLDKIDNDTLGVASDNLFDAKTEKKGVKATGDAIDANALGISGGTK 205 + V K ND G S + K T A + +A + Sbjct: 273 KEGDTFDYKGVTFTIDTKTGNDGNGKVSTTINGEKVTLTVADITAGAANVDAATLQSSKN 332 Query: 206 YATGVSVKEYKVDGKVSANKVVLKDGSDEYVVSKSDFTLKSGTT----TGEIEFTGSKTI 261 T V ++ D K L D V +G + T + Sbjct: 333 VYTSVVNGQFTFDDKTKNESAKLSDLEANNAVKGESKITVNGAEYTANAAGDKVTLAGKT 392 Query: 262 KFKADAGKDVKVLNVKDD---------ALATLDNAISKVDESRSKLGAIQNRFQSTINNL 312 F V L +D LA++D+A+SKVD RS LGAIQNRF S I NL Sbjct: 393 MFIDKTASGVSTLINEDAAAAKKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNL 452 Query: 313 NNTVNNLSASRSRILDADYATEVSNMSKNQILQQAGTAVLAQANQVPQTVLSLLR 367 NTV NL+++RSRI DADYATEVSNMSK QILQQAGT+VLAQANQVPQ VLSLLR Sbjct: 453 GNTVTNLNSARSRIEDADYATEVSNMSKAQILQQAGTSVLAQANQVPQNVLSLLR 507
>FLAGELLIN#Flagellin signature. Length = 507 Score = 169 bits (430), Expect = 2e-50 Identities = 151/351 (43%), Positives = 186/351 (52%), Gaps = 1/351 (0%) Query: 2 AQVINTNYLSLVTQNNLNKSQGTLGSAIERLSSGLRINSAKDDAAGQAIANRFTSNVNGL 61 AQVINTN LSL+TQNNLNKSQ +L SAIERLSSGLRINSAKDDAAGQAIANRFTSN+ GL Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 TQASRNANDGISIAQTTEGALNEINNNLQRIRELTVQAKNGTNSNSDITSIQNEVKERLD 121 TQASRNANDGISIAQTTEGALNEINNNLQR+REL+VQA NGTNS+SD+ SIQ+E+++RL+ Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 EINRISEQTQFNGVKVLSGEKSEMVIQVGTNDNETIKFNLDKVDNDTLGVASDKLFDAKT 181 EI+R+S QTQFNGVKVLS ++M IQVG ND ETI +L K+D +LG+ + K Sbjct: 121 EIDRVSNQTQFNGVKVLSQ-DNQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKE 179 Query: 182 EKKGVTEAGAAIDAKDIGVAGATSYDSGTVKEYKVDGVVSADKVIFNDGTKDYLVNKSDF 241 G ++ A + V V +A V + Sbjct: 180 ATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTD 239 Query: 242 ALEGADKAKFTGAKTTEFTADAGKDVKTLNVKDDALATLDKAINTIDESRSKLGAIQNRF 301 E + K + T D T + Sbjct: 240 DAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGNGKV 299 Query: 302 ESTINNLNNTVNNLSASRSRILDADYATEVSNMSRGQILQQAGTSVLAQAN 352 +TIN T+ + + S ++ T N Sbjct: 300 STTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKN 350 Score = 119 bits (300), Expect = 4e-32 Identities = 79/233 (33%), Positives = 108/233 (46%), Gaps = 4/233 (1%) Query: 131 QFNGVKVLSGEKSEMVIQVGTNDNETIKFNLDKVDNDTLGVASDKLFDAKTEKKGVTEAG 190 + GV K+ + + V + T G A+ + Sbjct: 279 DYKGVTFTIDTKTGNDGNGKVSTTINGEKVTLTVADITAGAANVDAATLQ----SSKNVY 334 Query: 191 AAIDAKDIGVAGATSYDSGTVKEYKVDGVVSADKVIFNDGTKDYLVNKSDFALEGADKAK 250 ++ T +S + + + + V + I +G + D Sbjct: 335 TSVVNGQFTFDDKTKNESAKLSDLEANNAVKGESKITVNGAEYTANAAGDKVTLAGKTMF 394 Query: 251 FTGAKTTEFTADAGKDVKTLNVKDDALATLDKAINTIDESRSKLGAIQNRFESTINNLNN 310 + T + LA++D A++ +D RS LGAIQNRF+S I NL N Sbjct: 395 IDKTASGVSTLINEDAAAAKKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGN 454 Query: 311 TVNNLSASRSRILDADYATEVSNMSRGQILQQAGTSVLAQANQVPQTVLSLLR 363 TV NL+++RSRI DADYATEVSNMS+ QILQQAGTSVLAQANQVPQ VLSLLR Sbjct: 455 TVTNLNSARSRIEDADYATEVSNMSKAQILQQAGTSVLAQANQVPQNVLSLLR 507
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 75.1 bits (184), Expect = 3e-21 Identities = 53/103 (51%), Positives = 72/103 (69%), Gaps = 2/103 (1%) Query: 9 SIPAIESVLDKMQIQTLQASNIAKPQPV-QAGFATQLVQAVGKINETRVNATNKVQAFTL 67 +I IE V+ ++Q T ++ + P FA QL A+ +I++T+ A + + FTL Sbjct: 2 AIQGIEGVISQLQ-ATAMSARAQESLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTL 60 Query: 68 GTPGVELNDVMVDMQKSSISLQMGVQVRNKLVAAYQEIMSMQV 110 G PGV LNDVM DMQK+S+S+QMG+QVRNKLVAAYQE+MSMQV Sbjct: 61 GEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV 103
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 538 bits (1388), Expect = 0.0 Identities = 321/556 (57%), Positives = 412/556 (74%), Gaps = 14/556 (2%) Query: 19 INRIKADPKIPLIIAGSAAIAIFVAAFLWLQSPDYKVLYSNLSDKDGGEIVTQLTQMNVP 78 +NR++A+P+IPLI+AGSAA+AI VA LW ++PDY+ L+SNLSD+DGG IV QLTQMN+P Sbjct: 16 LNRLRANPRIPLIVAGSAAVAIVVAMVLWAKTPDYRTLFSNLSDQDGGAIVAQLTQMNIP 75 Query: 79 YRLSQNGSAIMVPDNQVHELRLKLAQAGLPKGGAAGFELLDKEKFGISQFSEQINYQRAL 138 YR + AI VP ++VHELRL+LAQ GLPKGGA GFELLD+EKFGISQFSEQ+NYQRAL Sbjct: 76 YRFANGSGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQFSEQVNYQRAL 135 Query: 139 EGELARTIETLGPVQNARVHLALPKPSLFVREQKSPSASVTVGLLQGRALDEGQINAIVH 198 EGELARTIETLGPV++ARVHLA+PKPSLFVREQKSPSASVTV L GRALDEGQI+A+VH Sbjct: 136 EGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLEPGRALDEGQISAVVH 195 Query: 199 IVASSVAGMPDSNVTIVDQSGKLLTQPDALGRDLNSIQLKYVQELESRYQQRIETLLGPI 258 +V+S+VAG+P NVT+VDQSG LLTQ + GRDLN QLK+ ++ESR Q+RIE +L PI Sbjct: 196 LVSSAVAGLPPGNVTLVDQSGHLLTQSNTSGRDLNDAQLKFANDVESRIQRRIEAILSPI 255 Query: 259 VGRGNVHAQVTAQVDFSHTEETAEEYKPNQPPNQAAVRSKQVSQSEQNGGMLAGGVPGAL 318 VG GNVHAQVTAQ+DF++ E+T E Y PN ++A +RS+Q++ SEQ G GGVPGAL Sbjct: 256 VGNGNVHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQVGAGYPGGVPGAL 315 Query: 319 SNQPVAPPQAPIEKAKDTTADEKTTSTNANRSMTRNPNSNS-RLDETTNYEVDRRIRHVK 377 SNQP P +API + + T + + + + S + +ET+NYEVDR IRH K Sbjct: 316 SNQPAPPNEAPIATPPTNQQNAQNTPQTSTSTNSNSAGPRSTQRNETSNYEVDRTIRHTK 375 Query: 378 RPVGNIERLSVAVIVNYKTVEDKKKATEGEEPIVENKQVPLTDEQLQQIESLVREAMGYS 437 VG+IERLSVAV+VNYKT+ D K +PLT +Q++QIE L REAMG+S Sbjct: 376 MNVGDIERLSVAVVVNYKTLAD-------------GKPLPLTADQMKQIEDLTREAMGFS 422 Query: 438 QERGDSLSVVNSQFNDTEEPVISVPVWENPQILAKALDLGRWLLLVIIAWILWRKLVKPQ 497 +RGD+L+VVNS F+ + +P W+ + + L GRWLL++++AWILWRK V+PQ Sbjct: 423 DKRGDTLNVVNSPFSAVDNTGGELPFWQQQSFIDQLLAAGRWLLVLVVAWILWRKAVRPQ 482 Query: 498 LEKRREAEVAAQKAILKTKLEVTDDVNEAELDEESRRKQARQRVSAELQSQRIREMAEKD 557 L +R E AAQ+ + DE+ ++++A QR+ AE+ SQRIREM++ D Sbjct: 483 LTRRVEEAKAAQEQAQVRQETEEAVEVRLSKDEQLQQRRANQRLGAEVMSQRIREMSDND 542 Query: 558 PRVVAMVIRQWMSKEQ 573 PRVVA+VIRQWMS + Sbjct: 543 PRVVALVIRQWMSNDH 558
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 309 bits (794), Expect = e-107 Identities = 101/326 (30%), Positives = 193/326 (59%), Gaps = 2/326 (0%) Query: 3 NDLTGTEKSAVMLLTLGEDRAAEVFKHLTTREVQQLSIAMSSMRQISNQQLIDVMASFEE 62 + LTG +K+A++L+++G + +++VFK+L+ E++ L+ ++ + I+++ +V+ F+E Sbjct: 13 SALTGKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKLETITSELKDNVLLEFKE 72 Query: 63 DAVQYAALNVNANDYLRSVLVKALGEERANNLLDEISETRETTTGIETLNFMEPQMAADI 122 + + DY R +L K+LG ++A ++++ + + + E + +P + Sbjct: 73 LMMAQEFIQKGGIDYARELLEKSLGTQKAVDIINNL-GSALQSRPFEFVRRADPANILNF 131 Query: 123 IRDEHPQIIATILVHLKRGQAADILALFDEKLRNDVMLRIATFGGVQPSALAELTEVLNN 182 I+ EHPQ IA IL +L +A+ IL+ +++ +V RIA P + E+ VL Sbjct: 132 IQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVVREVERVLEK 191 Query: 183 LLDGQ-NLKRSKMGGVRTAAEIINLMKSQQEENVITAVRDYDGELAQKIIDEMFLFENLI 241 L + + GGV EIIN+ + E+ +I ++ + D ELA++I +MF+FE+++ Sbjct: 192 KLASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPELAEEIKKKMFVFEDIV 251 Query: 242 DIDNRSIQRILQEVESESLVVALKGCDQELRDHFLNNMSQRAAEIMRDDLASRGPVRMSQ 301 +D+RSIQR+L+E++ + L ALK D +++ NMS+RAA ++++D+ GP R Sbjct: 252 LLDDRSIQRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRAASMLKEDMEFLGPTRRKD 311 Query: 302 VEAEQKAILLIVRRLAESGEVVLHGG 327 VE Q+ I+ ++R+L E GE+V+ G Sbjct: 312 VEESQQKIVSLIRKLEEQGEIVISRG 337
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 177 bits (449), Expect = 9e-58 Identities = 96/231 (41%), Positives = 146/231 (63%), Gaps = 9/231 (3%) Query: 10 WKPWVPKELIDWELKVKEDTGLDEKEDENQEKEVVQQQKVLEQINMLDDMKEKAQKLGHA 69 WK W P +L + + E E E + LEQ L ++ +A + G+ Sbjct: 7 WKTWTPDDLAP-----PQAEFVPIVEPEETIIEEAEPS--LEQ--QLAQLQMQAHEQGYQ 57 Query: 70 EGFEAGKNQGYQEGYQAGLQSGIEEGIRQGIAKQEPFINEWQGLLAEFRHSLNGLDSVIA 129 G G+ QG+++GYQ GL G+E+G+ + ++Q P Q L++EF+ +L+ LDSVIA Sbjct: 58 AGIAEGRQQGHKQGYQEGLAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIA 117 Query: 130 SRLMQIALTAAKEVLGQPAVCDGSALLAQITLMLQQEQMFAGDPQLRINPKHIPLIEKEL 189 SRLMQ+AL AA++V+GQ D SAL+ QI +LQQE +F+G PQLR++P + ++ L Sbjct: 118 SRLMQMALEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDML 177 Query: 190 GDSLTAHGWKVVADNSIHVGGCRVVTNDGDLDSTIATRWHELCRLAAPEAL 240 G +L+ HGW++ D ++H GGC+V ++GDLD+++ATRW ELCRLAAP + Sbjct: 178 GATLSLHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQELCRLAAPGVV 228
>FLGFLIJ#Flagellar FliJ protein signature. Length = 147 Score = 90.3 bits (223), Expect = 4e-26 Identities = 68/146 (46%), Positives = 100/146 (68%), Gaps = 1/146 (0%) Query: 1 MREQSPLVTLRELAQTAAEQAAVQLAQVRQSHQQMEQQLNMLIGYQDEYRVRLNQTLNVG 60 M E L TL++LA+ E AA L ++R+ QQ E+QL MLI YQ+EYR LN ++ Sbjct: 1 MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMS-A 59 Query: 61 GMSSASWQNYQQFLKTLELTIEQHKQQLRHWQAQLDLATEHWREKQQRLNAFETLEQRAE 120 G++S W NYQQF++TLE I QH+QQL W ++D+A WREK+QRL A++TL++R Sbjct: 60 GITSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQS 119 Query: 121 DSRKRQLDRIEQKQMDEYAQRSTLRR 146 + +R++QK+MDE+AQR+ +R+ Sbjct: 120 TAALLAENRLDQKKMDEFAQRAAMRK 145
>STREPKINASE#Streptococcus streptokinase protein signature. Length = 440 Score = 27.8 bits (61), Expect = 0.021 Identities = 19/47 (40%), Positives = 25/47 (53%) Query: 5 DINKAIREQLIKQLIKTDINAEVITGYQPEEITDNNIIMFFPIKEVS 51 D+ KAI+EQLI + D EVI ITD N ++F K+ S Sbjct: 104 DLLKAIQEQLIANVHSNDDYFEVIDFASDATITDRNGKVYFADKDGS 150
>SECA#SecA protein signature. Length = 901 Score = 27.9 bits (62), Expect = 0.018 Identities = 17/71 (23%), Positives = 28/71 (39%), Gaps = 4/71 (5%) Query: 25 RNKILKQKYVKINETLTQQIVENKNYQLRIKQLYQMDTQ---RLQELASAKSEIDRLRSY 81 R +IL Q E + + L +D+ L + + I LR Y Sbjct: 736 RERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIH-LRGY 794 Query: 82 AERDPERVYIR 92 A++DP++ Y R Sbjct: 795 AQKDPKQEYKR 805
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 53.3 bits (128), Expect = 1e-10 Identities = 25/131 (19%), Positives = 59/131 (45%), Gaps = 20/131 (15%) Query: 1 MNNLNIIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTSLINNLSKLNADALITDLSMP 60 M I++ADD + + ++L + + + ++ +L ++ + D ++TD+ MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRI--TSNAATLWRWIAAGDGDLVVTDVVMP 58 Query: 61 GDKYGDGITLIKYIKRHYPNLSIIVLTMNNNPAILSAVLDLEIEGIVLKQGA------PA 114 + L+ IK+ P+L ++V++ N +A+ ++GA P Sbjct: 59 D---ENAFDLLPRIKKARPDLPVLVMSAQNTFM--TAIKA-------SEKGAYDYLPKPF 106 Query: 115 DLPKALAALQK 125 DL + + + + Sbjct: 107 DLTELIGIIGR 117
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 75.6 bits (186), Expect = 3e-16 Identities = 23/104 (22%), Positives = 48/104 (46%) Query: 827 TVLIVDDHPINRLLLTDQLKKIGFNTATAEDGCDALAFMQENHVDIILTDVNMPNMNGYQ 886 T+L+ DD R +L L + G++ + ++ D+++TDV MP+ N + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 887 LATTVRELSRTIPIIGVTANAIAEEKQRCIDAGMNDCVSKPVSL 930 L +++ +P++ ++A + + G D + KP L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDL 108
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 200 bits (509), Expect = 1e-59 Identities = 61/192 (31%), Positives = 106/192 (55%) Query: 373 DKDPRPQQEKEFNDIKDGVKFTISFYEKVTQEFGKKAAQLSRELAEQAKGKTIRSVEDAL 432 + + Q + IKD V T+SFY+ +T+++G+K +++++ELA+++KGK I +V +AL Sbjct: 331 ENLKKAQNNLLNSQIKDAVDATVSFYQTLTEKYGEKYSKMAQELADKSKGKKIGNVNEAL 390 Query: 433 RTYEKYGQNINNKINAKDRAAIIKALESIDAKQLASNLGKFSKGLGYTNHAINAVELLVE 492 +EKY +N K + DR AI AL S+ A +L +F+K L T H +++ + Sbjct: 391 AAFEKYKDVLNKKFSKADRDAIFNALASVKYDDWAKHLDQFAKYLKITGHVSFGYDVVSD 450 Query: 493 FKKAVKTGNWRPFFVKATAITAGMAAVALTAFAFSLIVGGPVGILGYALIIATVSALIDD 552 K TG+W+P F+ A + A FSL+ G +GI G A++ + + ID Sbjct: 451 ILKIKDTGDWKPLFLTLEKKAADAGVSYVVALLFSLLAGTTLGIWGIAIVTGILCSYIDK 510 Query: 553 ALVEKVSSAIGI 564 + ++ +GI Sbjct: 511 NKLNTINEVLGI 522
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 48.3 bits (114), Expect = 4e-08 Identities = 56/243 (23%), Positives = 82/243 (33%), Gaps = 7/243 (2%) Query: 101 AITSAQSTLIPGKTLNKATLAPVAVFTPTLTTASTTTAIETLGAILGRALGLGAGLMLYS 160 AI +A + +P AT A + AS AI A+LGR L +M Sbjct: 243 AIRAANTYAMPANGSVVATAAGRGLIQVAQGAASLAQAISDAIAVLGRVLASAPSVMAVG 302 Query: 161 PPVGEGSDRYPAMIYDEYPKNRETALTREGRVLNIPKETQLREIAKQKGMINTSAVIVEK 220 S R D+ P + AL + L +P L +AK G ++ + + Sbjct: 303 FASLTYSSRTAEQWQDQTPDSVRYALGMDAAKLGLPPSVNLNAVAKASGTVDLPMRLTNE 362 Query: 221 GVNGAKQIELVKTE----TPVKTRVVEARKTAEKGVFAYTLPNEKQERKVQIGNATILKG 276 G V + P V A A G++ T+P+ E I T Sbjct: 363 -ARGNTTTLSVVSTDGVSVPKAVPVRMAAYNATTGLYEVTVPSTTAEAPPLI--LTWTPA 419 Query: 277 IAPPQPKRHRYLPGKVYDISRFNELPLEAPTFFSENEKRQSILREPVILIFPWELGIKPI 336 P P + + L E L E +I+ FP + GIKPI Sbjct: 420 SPPGNQNPSSTTPVVPKPVPVYEGATLTPVKATPETYPGVITLPEDLIIGFPADSGIKPI 479 Query: 337 YLS 339 Y+ Sbjct: 480 YVM 482
>FIMBRIALPAPF#Escherichia coli: P pili tip fibrillum papF protein signature. Length = 167 Score = 29.7 bits (66), Expect = 0.007 Identities = 21/74 (28%), Positives = 39/74 (52%), Gaps = 10/74 (13%) Query: 14 ISTPVLAKAPVANLKIN--GDIKPPTCTINGATQSDMIFDYRVISPTLIPQSKNYEYPNG 71 IS + + A +A+++IN G++ P CTIN +++ D+ I+P + S+ G Sbjct: 8 ISLLLTSVAVLADVQINIRGNVYIPPCTINNG--QNIVVDFGNINPEHVDNSR------G 59 Query: 72 IVQNTVTIECDAKT 85 V ++I C K+ Sbjct: 60 EVTKNISISCPYKS 73
>FIMBRIALPAPF#Escherichia coli: P pili tip fibrillum papF protein signature. Length = 167 Score = 30.1 bits (67), Expect = 0.004 Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 12/85 (14%) Query: 1 MKKLLLSLTMLAIISTPVLAKSPVANLKINGDIKPPTCTINGATQSDVIFDYGVISPTLI 60 M +L L +++L + S VLA + I G++ P CTIN +++ D+G I+P + Sbjct: 1 MIRLSLFISLL-LTSVAVLAD---VQINIRGNVYIPPCTINNG--QNIVVDFGNINPEHV 54 Query: 61 PQSKIYSYPASMVQNTVTVECDAKT 85 S+ V +++ C K+ Sbjct: 55 DNSR------GEVTKNISISCPYKS 73
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 26.8 bits (59), Expect = 0.027 Identities = 7/26 (26%), Positives = 11/26 (42%) Query: 43 GYSYYQKGDYKEAFNYFSQHAESDPQ 68 ++ YQ G Y++A F D Sbjct: 43 AFNQYQSGKYEDAHKVFQALCVLDHY 68
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 63.2 bits (153), Expect = 2e-12 Identities = 46/303 (15%), Positives = 101/303 (33%), Gaps = 4/303 (1%) Query: 380 SAKKEIEVLQNSLTNLSAVRQSLENQLAKNKASFEATLAKNNQLIDTQRQQIAQLNDHIK 439 K ++ + LT + + + K+ + + + + + + + Sbjct: 78 FNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFST 137 Query: 440 KINQEQQQLNHSLVTLQQQKAQADDQLTQIPALKLELQNKVNELAELKKSLSTGEKAFDA 499 + + + L L +KA + L K+ L K +L + + Sbjct: 138 ADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEK 197 Query: 500 LISEKNGVIAKLEKAQADLANKYQALDTQFKENNTTIGQLKESKIANDNAYAQLEKQLAE 559 + L + AL + + + A+ LE + A Sbjct: 198 ALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAA 257 Query: 560 KQSLTDKLTTQLTQAKDQLAKQNSESNQLIASLKQQQVESTAQFKQQESVLANSQKEFNE 619 ++ +L L A + +++ L A + E Q + + AN Q Sbjct: 258 LEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQS---- 313 Query: 620 VSKQLEAQRALTKTLEEKELKLSEQLKEKESEIKKINSESASVQKENKTLKQQLDKAMGE 679 + + L+A R K LE + KL EQ K E+ + + + + ++ K L+ + K + Sbjct: 314 LRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQ 373 Query: 680 GQI 682 +I Sbjct: 374 NKI 376 Score = 63.2 bits (153), Expect = 3e-12 Identities = 58/372 (15%), Positives = 121/372 (32%), Gaps = 11/372 (2%) Query: 229 NRLANTREKYQRLYQKFTEQAALLTESLTKLQTAEEKVQQLTAELAKTQDKLAVANNLLN 288 R + L K ++ + E++ +L K L+ + + Sbjct: 57 ERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKI- 115 Query: 289 DDSLKQSVAKLQNELAQSKKEQDTLLAQLAEKDQLLFDATEKNKVLTKQQEDFDIQAQ-- 346 L+ A L+ L + A++ + + L K E + Sbjct: 116 -QELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTAD 174 Query: 347 --KLNQLTTHVAQLEQQKQQLQSQYGQAQRLLTNNSAKKEIEVLQNSLTNLSAVRQSLEN 404 K+ L A LE ++ +L+ A + + +I+ L+ L+A + LE Sbjct: 175 SAKIKTLEAEKAALEARQAELEKALEGAMNF--STADSAKIKTLEAEKAALAARKADLEK 232 Query: 405 QLAKNKASFEATLAKNNQLIDTQRQQIAQLNDHIKKINQEQQQLNHSLVTLQQQKAQADD 464 L A AK L + A+ + K + ++ +A+ Sbjct: 233 ALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAA 292 Query: 465 QLTQIPALKLELQNKVNELAELKKSLSTGEKAFDALISEKNGVIAKL---EKAQADLANK 521 + L+ + Q L++ L +A L +E + + E ++ L Sbjct: 293 LEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRD 352 Query: 522 YQALDTQFKENNTTIGQLKESKIANDNAYAQLEKQLAEKQSLTDKLTTQLTQAKDQLAKQ 581 A K+ +L+E ++ + L + L + ++ L +A +LA Sbjct: 353 LDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAAL 412 Query: 582 NSESNQLIASLK 593 + +L S K Sbjct: 413 EKLNKELEESKK 424 Score = 61.6 bits (149), Expect = 8e-12 Identities = 86/424 (20%), Positives = 157/424 (37%), Gaps = 30/424 (7%) Query: 260 QTAEEKVQQLTAELAKTQDKLAVANNLLNDDS--LKQSVAKLQNELAQSKKEQDTLLAQL 317 EKVQ+ + + L + N+ L+ ++ LK +L EL+ +K++ L Sbjct: 49 TDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSL 108 Query: 318 AEKDQLLFDATEKNKVLTKQQEDFDIQAQKLNQLTTHVAQLEQQKQQLQSQYGQAQRLLT 377 +EK + + + L K E + + LE +K L ++ Sbjct: 109 SEKASKIQELEARKADLEKALEG---AMNFSTADSAKIKTLEAEKAALAAR--------- 156 Query: 378 NNSAKKEIEVLQNSLTNLSAVRQSLENQLAKNKAS---FEATLAKNNQLIDTQRQQIAQL 434 +K +E N T SA ++LE + A +A E L +I L Sbjct: 157 KADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTL 216 Query: 435 NDHIKKINQEQQQLNHSLVTLQQQKAQADDQLTQIPALKLELQNKVNELAELKKSLSTGE 494 + + L +L ++ + A K L+ + EL + + Sbjct: 217 EAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGA---- 272 Query: 495 KAFDALISEKNGVIAKLEKAQADLANKYQALDTQFKENNTTIGQLKESKIANDNAYAQLE 554 + + I LE +A L + L+ Q + N L+ A+ A QLE Sbjct: 273 ---MNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLE 329 Query: 555 ---KQLAEKQSLTDKLTTQLTQAKDQLAKQNSESNQLIASLKQQQVESTAQFKQQESVLA 611 ++L E+ +++ L + D + + L++Q S A + L Sbjct: 330 AEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLD 389 Query: 612 NSQKEFNEVSKQLEAQRALTKTLEEKELKLSEQLKEKESEIKKINSESASVQKENKTLKQ 671 S++ +V K LE + LE+ +L E K E E ++ A ++ E K LK+ Sbjct: 390 ASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQ---AKLEAEAKALKE 446 Query: 672 QLDK 675 +L K Sbjct: 447 KLAK 450 Score = 53.1 bits (127), Expect = 3e-09 Identities = 72/378 (19%), Positives = 127/378 (33%), Gaps = 13/378 (3%) Query: 224 NKELLNRLANTREKYQRLYQKFTEQAALLTESLTKLQTAEEKVQQLTAELAKTQDKLAVA 283 N EL L+N +EK ++ + +E+A+ + E + E+ ++ K+ Sbjct: 87 NDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTL 146 Query: 284 NNLLND--DSLKQSVAKLQNELAQSKKEQDTLLAQLAEKDQLLFDATEKNKVLTKQQEDF 341 L+ + S + + AEK L E K L Sbjct: 147 EAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFS 206 Query: 342 DIQAQKLNQLTTHVAQLEQQKQQLQSQYGQAQRLLTNNSAK-----KEIEVLQNSLTNLS 396 + K+ L A L +K L+ A T +SAK E L+ L Sbjct: 207 TADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELE 266 Query: 397 AVRQSLENQLAKNKASFEATLAKNNQLIDTQRQ---QIAQLNDHIKKINQEQQQLNHSLV 453 + N + A + A+ L + Q LN + + + ++ + Sbjct: 267 KALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKK 326 Query: 454 TLQQQKAQADDQLTQIPALKLELQNKVNELAELKKSLSTGEKAFDALISEKNGVIAKLEK 513 L+ + + ++Q A + L+ ++ E KK L E L + A + Sbjct: 327 QLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQL---EAEHQKLEEQNKISEASRQS 383 Query: 514 AQADLANKYQALDTQFKENNTTIGQLKESKIANDNAYAQLEKQLAEKQSLTDKLTTQLTQ 573 + DL +A K +L + N + EK L KL + Sbjct: 384 LRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKA 443 Query: 574 AKDQLAKQNSESNQLIAS 591 K++LAKQ E +L A Sbjct: 444 LKEKLAKQAEELAKLRAG 461 Score = 41.6 bits (97), Expect = 1e-05 Identities = 50/292 (17%), Positives = 102/292 (34%), Gaps = 18/292 (6%) Query: 224 NKELLNRLANTREKYQRLYQKFTEQAALLTESLTKLQTAEEKVQQLTAELAKTQDKLAVA 283 EL L K A + E+ ++ K+ Sbjct: 192 QAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTL 251 Query: 284 NNLLND-----DSLKQSVAKLQNELAQSKKEQDTLLAQLAEKDQLLFDATEKNKVL---- 334 L++++ N + TL A+ A + D +++VL Sbjct: 252 EAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANR 311 Query: 335 TKQQEDFDIQAQKLNQLTTHVAQLEQQKQQLQ-SQYGQAQRLLTNNSAKKEIEVLQNSLT 393 + D D + QL +LE+Q + + S+ + L + AKK++E Sbjct: 312 QSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEA---EHQ 368 Query: 394 NLSAVRQSLENQLAKNKASFEATLAKNNQLIDTQRQQIAQLNDHIKKINQEQQQLNHSLV 453 L + E + +A+ Q+ + + + N + + + ++L S Sbjct: 369 KLEEQNKISEASRQSLRRDLDASREAKKQV----EKALEEANSKLAALEKLNKELEESKK 424 Query: 454 TLQQQKAQADDQL-TQIPALKLELQNKVNELAELKKSLSTGEKAFDALISEK 504 +++KA+ +L + ALK +L + ELA+L+ ++ + DA K Sbjct: 425 LTEKEKAELQAKLEAEAKALKEKLAKQAEELAKLRAGKASDSQTPDAKPGNK 476
>PF04647#Accessory gene regulator B Length = 212 Score = 29.4 bits (66), Expect = 0.009 Identities = 15/66 (22%), Positives = 28/66 (42%), Gaps = 11/66 (16%) Query: 5 FIVSIFLFLISVVCITLGMIKPSIIKLKNRKQSFIAFLITFVLSIIGVLNFAP-DTPNNQ 63 + S+ +F + I L + + LI F+ S++ +L P D P N Sbjct: 81 TLTSLLVFNVL----------AYIAHLIDPAYFQLLILIAFITSLLALLFLVPVDNPRNL 130 Query: 64 ITETQE 69 I+ T++ Sbjct: 131 ISNTEQ 136
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 42.5 bits (100), Expect = 7e-06 Identities = 22/189 (11%), Positives = 66/189 (34%), Gaps = 17/189 (8%) Query: 22 RSAQESNKRLASAVRQSRDSLKTLNQQASQIDGFRKIKQQLTSTQQAYQSATQRVATLAK 81 R ++ ++ Q L+++ ++ + + + +S ++L Sbjct: 186 RLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLH 245 Query: 82 EIANSENPTKKQLEAFKKAQREAGQLKTKYEQLQQSVQRQRSALQANGISTNQLGQAQRR 141 + A +++ +Q + +A E K++ EQ++ + + Q + Sbjct: 246 KQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQ------LVTQLFKNE 299 Query: 142 LNGDIERTTQQLRRQENQLRRSAEQERRMVAAKSQYQKTLDVRNKMAGTGATMTATGAGM 201 + + +TT + +L E+ ++ +R ++ + G Sbjct: 300 ILDKLRQTTDNIGLLTLEL-AKNEERQQA----------SVIRAPVSVKVQQLKVHTEGG 348 Query: 202 LYSAKQTLM 210 + + +TLM Sbjct: 349 VVTTAETLM 357
>PF05932#Tir chaperone protein (CesT) Length = 127 Score = 27.8 bits (62), Expect = 0.020 Identities = 10/75 (13%), Positives = 26/75 (34%), Gaps = 11/75 (14%) Query: 15 RIMDKLIPHLPKARRL-VEPFA----GSCAVMMNTEYEEYLIADANQDLINLYRSVSKNP 69 L+ +R L ++P G+C ++++ + L D ++ + L + + Sbjct: 4 LFYKTLLDDF--SRSLEMQPLVFDDHGTCNMIIDNTFALTLSCDYARERLLLIGLLEPHK 61 Query: 70 DVMACSDLYDWKQQN 84 D+ Sbjct: 62 DIP----QQCLLAGA 72
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 310 bits (796), Expect = e-103 Identities = 129/446 (28%), Positives = 231/446 (51%), Gaps = 8/446 (1%) Query: 17 KKEPKNYDFYPNHIAVLEKPPTPYSRIIAIIISLSVIIFLLWAYIGKLDVLSSAIGKLVV 76 +E +F P H+ ++E P + R++A I ++I + + +G+++++++A GKL Sbjct: 33 VREKDENEFLPAHLELIETPVSRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTH 92 Query: 77 SGYSQQIQIYEHSRLSAIHVKNGQQVTKGEALLTLDILGVDEEINNLKNKIENLLLLKIR 136 SG S++I+ E+S + I VK G+ V KG+ LL L LG + + ++ + L + R Sbjct: 93 SGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTR 152 Query: 137 YQALGQNTRPDTI--------DDFNLLNKEKKEAVLLSYQKEKDEFDASINHINSEIETN 188 YQ L ++ + + F +++E+ + +++ + ++ Sbjct: 153 YQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKK 212 Query: 189 NKNKLLTHQEINSLNELKNNIEKRFNIKKKLYDKKIISTMEFLENKKELLEINQIIKRKS 248 +L IN L + R + L K+ I+ LE + + +E ++ Sbjct: 213 RAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYK 272 Query: 249 SELVILSSQEQQYIKNRDRLEKQKHLEWHDKFKQYESGVFIYQQNLYHVQKRQQLKIVRS 308 S+L + S+ + + + E DK +Q + + L ++RQQ ++R+ Sbjct: 273 SQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRA 332 Query: 309 PVTGTVQQLAVHTLGAVLQPSQAVMVIVPDTQHNVAEVNILNKDIGFIYPGQKAVIKIDA 368 PV+ VQQL VHT G V+ ++ +MVIVP+ + NKDIGFI GQ A+IK++A Sbjct: 333 PVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEA 392 Query: 369 FPYTRYGTIEGTIVNIAKDSIQHEQLGLVYPVLIELDKQVMGEDEAQYKLATGMSLVADI 428 FPYTRYG + G + NI D+I+ ++LGLV+ V+I +++ + L++GM++ A+I Sbjct: 393 FPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEI 452 Query: 429 KIEKRRVIDYLLSPIEVYQHEALREK 454 K R VI YLLSP+E E+LRE+ Sbjct: 453 KTGMRSVISYLLSPLEESVTESLRER 478
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.6 bits (69), Expect = 0.020 Identities = 12/60 (20%), Positives = 27/60 (45%), Gaps = 2/60 (3%) Query: 16 EVTEVMVKVGDRIEE-EQSLITVEGDKASMEVPSPQAGIVKEIKI-AVGDKVETGSLIMI 73 E+ + + + D I L E + + + +P + V+++K+ G V T +M+ Sbjct: 299 EILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMV 358 Score = 29.4 bits (66), Expect = 0.044 Identities = 13/59 (22%), Positives = 26/59 (44%), Gaps = 2/59 (3%) Query: 213 EVTEVMVKVGDTIAE-EQSLITVEGDKASMEVPAPFAGVVKEIKI-AVGDKVKTGSLIM 269 E+ + + + D I L E + + + AP + V+++K+ G V T +M Sbjct: 299 EILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLM 357
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 42.2 bits (99), Expect = 1e-07 Identities = 17/52 (32%), Positives = 32/52 (61%) Query: 10 ENGFTLMELMIVIAIISILSSVAIPAYHGYIQKAALTDVLQTLSPYRSAVEL 61 + GFTL+E+M+VI II +L+S+ +P G +KA + + +A+++ Sbjct: 7 QRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDM 58
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 185 bits (471), Expect = 1e-56 Identities = 86/406 (21%), Positives = 171/406 (42%), Gaps = 17/406 (4%) Query: 7 YRYNALTYQGKWLSGNVVAQSKHEVIDQLIQQQKLPVKIRLYRVIIFQNSDKQYRI---- 62 Y Y AL QGK G A S + L ++ +P+ + R ++ + Sbjct: 4 YHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLRRKI 63 Query: 63 --------QLLEQLALLLHSGLALLPALTLLKEECRYLHWQCVLNDIIFHLNQGGALSKQ 114 L QLA L+ + + L AL + ++ H ++ + + +G +L+ Sbjct: 64 RLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLADA 123 Query: 115 LSRYPLYFPANLTHFIYIGEESGKLDEVLLLQTTQLKNQRDLIKKIIKAFQYPLFLLLTL 174 + +P F + GE SG LD VL + ++ + +I +A YP L + Sbjct: 124 MKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLTVVA 183 Query: 175 IVITISMLIYVLPEYQSLYSAFNTELPMLTLTLIRCSQWFSQYS--LIILLFILIISYSY 232 I + +L V+P+ + LP+ T L+ S + +++ L +++ Sbjct: 184 IAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMAFRV 243 Query: 233 YTIKHHSAKFRDIEQRCWLNLPYLGVLLRYHQLHIIFQIMTITQQAGLPLLQGLKIITEQ 292 + K R R L+LP +G + R + ++I + +PLLQ ++I + Sbjct: 244 MLRQE---KRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 293 LTHSLYQRALTDMIAHITQGKSLSSFMRHNPLFPPICYQLISSAENSGQLQFFCQQLTHW 352 +++ + L+ + +G SL + LFPP+ +I+S E SG+L ++ Sbjct: 301 MSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADN 360 Query: 353 FYHQLEERLDSVKTWLEPILMTLIALITGTLIIAMYLPVLQLGDTI 398 + ++ EP+L+ +A + +++A+ P+LQL + Sbjct: 361 QDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 40.8 bits (95), Expect = 2e-06 Identities = 42/180 (23%), Positives = 68/180 (37%), Gaps = 22/180 (12%) Query: 1 MSTPANF--NGQRPVINPDDAVMLLIDHQSGLFQTVGD--MPMTELRARAAVLAKMATLA 56 M T ++ N V +P+ AV+L+ D Q+ P+TEL A L Sbjct: 11 MPTASDMPQNKVSWVPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCVQL 70 Query: 57 KMPVITTAS-VPQGPNGPLI------PEIHQNAPHAKYVAR-----------KGEINAWD 98 +PV+ TA Q P+ + P ++ K + K +A+ Sbjct: 71 GIPVVYTAQPGSQNPDDRALLTDFWGPGLNSGPYEEKIITELAPEDDDLVLTKWRYSAFK 130 Query: 99 NPEFVEAVKATGKKQLIIAGTITSVCMAFPAISAVAEGYQVFAVIDASGTYSKMAEEITL 158 +E ++ G+ QLII G + A A E + F V DA +S ++ L Sbjct: 131 RTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVADFSLEKHQMAL 190
>FIMBRIALPAPF#Escherichia coli: P pili tip fibrillum papF protein signature. Length = 167 Score = 30.8 bits (69), Expect = 0.001 Identities = 36/171 (21%), Positives = 72/171 (42%), Gaps = 17/171 (9%) Query: 5 LTLFLLFSYSPIALSNTVNINVYGSVVASPCELET-KNHLIDLKKINIRNIKNGQASDWI 63 L+LF+ + +A+ V IN+ G+V PC + +N ++D IN ++ N + Sbjct: 4 LSLFISLLLTSVAVLADVQINIRGNVYIPPCTINNGQNIVVDFGNINPEHVDNSRGEVTK 63 Query: 64 DFSIKLKNCPVNTEKVTMILRGQSV---------PNYSEYFINSGTAKDIALNLAMQNNK 114 + SI +CP + + + + G ++ N + + I K ++ L + N Sbjct: 64 NISI---SCPYKSGSLWIKVTGNTMGVGQNNVLATNITHFGIALYQGKGMSTPLTLGNGS 120 Query: 115 GIVKNNDKLMTAVNKYNHNAEFALSARMVGYGNNITVGSFKSHLEFTLIYN 165 G N ++ ++ F G G + G F++ ++IYN Sbjct: 121 G---NGYRVTAGLDTARSTFTFTSVPFRNGSG-ILNGGDFRTTASMSMIYN 167
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 28.6 bits (63), Expect = 0.015 Identities = 25/113 (22%), Positives = 45/113 (39%), Gaps = 12/113 (10%) Query: 57 SLFNKVNSSSVWNDFNIKLIDCSPGVNQVKLTFSGTPDNADVNNLYKNEGTAKNIAVQLQ 116 SL ++ W D + + G++ KL G P + ++N + K GT ++ ++L Sbjct: 305 SLTYSSRTAEQWQDQTPDSVRYALGMDAAKL---GLPPSVNLNAVAKASGTV-DLPMRLT 360 Query: 117 NKNSNGEIPLGNGKNLYIAVNGKPSVTVPLRTRAFSKLGNATPGTVSAKITAT 169 N+ G ++V V+VP NAT G + +T Sbjct: 361 NE--------ARGNTTTLSVVSTDGVSVPKAVPVRMAAYNATTGLYEVTVPST 405
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 754 bits (1948), Expect = 0.0 Identities = 341/871 (39%), Positives = 506/871 (58%), Gaps = 56/871 (6%) Query: 5 KVCISLILYLGYAALLYAENNNLDDIYFDPDFLELPNKDIIDLSSFEN-NQQLAGDYYVD 63 ++ + A + ++YF+P FL + + DLS FEN + G Y VD Sbjct: 22 RLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVD 81 Query: 64 IYVNTNLILTKNIRFDKDKNNQ-LKPCLSVNDLNDFGVKTTDYPGL-YSEYTSCVNL-SA 120 IY+N + T+++ F+ + Q + PCL+ L G+ T G+ +CV L S Sbjct: 82 IYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLTSM 141 Query: 121 IPEAKSELDFDSQRLYLSIPQIALSKNPRGYIELDNIDNGINALLLNYSYSGSKNYDRKN 180 I +A ++LD QRL L+IPQ +S RGYI + D GINA LLNY++SG+ +R Sbjct: 142 IHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIG 201 Query: 181 GSSNTTSNYINLRPGLNLGPWRLRNYTTWS-----STSNQSGKWNTLYTYLSRNINKIKS 235 G+S+ Y+NL+ GLN+G WRLR+ TTWS S+S KW + T+L R+I ++S Sbjct: 202 GNSH--YAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRS 259 Query: 236 QLILGDGISSSDVFDSVPFRGMQLSTDDEMYPESLRGYAPIIRGIAKSNSQITIKQNGYT 295 +L LGDG + D+FD + FRG QL++DD M P+S RG+AP+I GIA+ +Q+TIKQNGY Sbjct: 260 RLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYD 319 Query: 296 IYQTEVAAGPFEINDLYPSGSSGDLYVTIKGANGSEQHQIVPFASLPVLQREGHFTYSVT 355 IY + V GPF IND+Y +G+SGDL VTIK A+GS Q VP++S+P+LQREGH YS+T Sbjct: 320 IYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSIT 379 Query: 356 GGEYRAYDNNVDKTKFGQFTLVYGLPYGTTAYGGSQLSQNYQSYSLGVGKNLGSFGAVSV 415 GEYR+ + +K +F Q TL++GLP G T YGG+QL+ Y++++ G+GKN+G+ GA+SV Sbjct: 380 AGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSV 439 Query: 416 DVTQAKSTFNDGRKQQGQSYRFRYNKNLNNIGTNIALAGYRYSTSGFYSLSEVFDSFRR- 474 D+TQA ST D + GQS RF YNK+LN GTNI L GYRYSTSG+++ ++ S Sbjct: 440 DMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNG 499 Query: 475 ----------------THYSPEIEQRRHRAEITLNQNLGDKYGSLAIGYIQEDYWNSKSK 518 T Y +R + ++T+ Q LG +L + + YW + + Sbjct: 500 YNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGR-TSTLYLSGSHQTYWGTSNV 558 Query: 519 KQSATLGYNNSWQGISYGINYTYNKNTVNHSYIADQKRQNDDEHLLAFSVNVPFS----- 573 + G N +++ I++ ++Y+ KN Q + +LA +VN+PFS Sbjct: 559 DEQFQAGLNTAFEDINWTLSYSLTKNA----------WQKGRDQMLALNVNIPFSHWLRS 608 Query: 574 ---VFDNTFYYNFNANSNNNSSSTGSVGISASQL-NNRLNWSVQQAFT---NQDQGSSGN 626 +++ + + N T G+ + L +N L++SVQ + + + GS+G Sbjct: 609 DSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGY 668 Query: 627 INASYKGQLGDITGGYSYSKDNHNLYYGVSGSVVAHSQGVVFGQQLGETAAIVDIPNAGD 686 +Y+G G+ GYS+S D LYYGVSG V+AH+ GV GQ L +T +V P A D Sbjct: 669 ATLNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKD 728 Query: 687 ITILNQAGVRTNNSGYALVPYVTPYRKNTVEIDTLRLPENAEMELTSQTVLPSRGALVKA 746 + NQ GVRT+ GYA++PY T YR+N V +DT L +N +++ V+P+RGA+V+A Sbjct: 729 AKVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRA 788 Query: 747 NFSANVGYRVLMTINLENKKPVPFGAQAIFKDNSQLNSIVGNDGEVYLSGLKQKGNFTIK 806 F A VG ++LMT+ N KP+PFGA + ++SQ + IV ++G+VYLSG+ G +K Sbjct: 789 EFKARVGIKLLMTLTHNN-KPLPFGAM-VTSESSQSSGIVADNGQVYLSGMPLAGKVQVK 846 Query: 807 YN---NESCQVNYDLSDIPDYLGLYKTTVTC 834 + N C NY L L + + C Sbjct: 847 WGEEENAHCVANYQLPPESQQQLLTQLSAEC 877
>PF07824#Type III secretion chaperone Length = 120 Score = 31.4 bits (71), Expect = 0.002 Identities = 8/34 (23%), Positives = 14/34 (41%) Query: 77 AEEGNYRYWIRLPQTNTWQKHSSGLSYYLSNLSW 110 E G+ + L N ++ YY+S + W Sbjct: 75 DEGGSLIARLDLTGINEFEDIYVNTEYYISRVRW 108
>FIMBRIALPAPF#Escherichia coli: P pili tip fibrillum papF protein signature. Length = 167 Score = 109 bits (274), Expect = 6e-33 Identities = 65/167 (38%), Positives = 93/167 (55%), Gaps = 10/167 (5%) Query: 15 LLSGTARAVDINIAITGAIYVPPCVVNNNIPIQFSFNQIMTYKVDGQTSAITKNIPITCT 74 LL+ A D+ I I G +Y+PPC +NN I F I VD +TKNI I+C Sbjct: 11 LLTSVAVLADVQINIRGNVYIPPCTINNGQNIVVDFGNINPEHVDNSRGEVTKNISISCP 70 Query: 75 YFKGSPYVKVSGIQLAGAPDNVLKVSADSVNSNRFGLALYQGESVDENNPLRLNGSAPRG 134 Y GS ++KV+G + +NVL + N FG+ALYQG+ + + PL L + G Sbjct: 71 YKSGSLWIKVTGNTMGVGQNNVL-----ATNITHFGIALYQGKGM--STPLTLGNGSGNG 123 Query: 135 YAITKGFSNTGQDRSQFTITAVPFKTGTADLSPGNFTASASLSIVYN 181 Y +T G RS FT T+VPF+ G+ L+ G+F +AS+S++YN Sbjct: 124 YRVTAGLDTA---RSTFTFTSVPFRNGSGILNGGDFRTTASMSMIYN 167
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 660 bits (1703), Expect = 0.0 Identities = 226/852 (26%), Positives = 375/852 (44%), Gaps = 64/852 (7%) Query: 23 SVEFNLDVVDSKSKDNINFARFSEAGYILPGKYQLNLVLNGQGIGSSTYTVNVLERENKS 82 + FN + + + +RF + PG Y++++ LN + + T N + Sbjct: 46 ELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGYMATRDVTFN-------T 98 Query: 83 QDENKKLLSQACLTGDIISSLGLKEKIENNLPTWNDGKCIDLLSL-DGVEVTTKLNEGIL 141 D + + CLT ++S+GL + + D C+ L S+ + + L Sbjct: 99 GDSEQGI--VPCLTRAQLASMGLNTASVSGMNLLADDACVPLTSMIHDATAQLDVGQQRL 156 Query: 142 SIKIPQIWLEYTSATWLPPSRWDDGISGLILDYNINTNVNIPHEGSNTQSIYYNGTVGYN 201 ++ IPQ ++ + ++PP WD GI+ +L+YN + N G N+ Y N G N Sbjct: 157 NLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNSHYAYLNLQSGLN 216 Query: 202 FGSWRIRSDYQGNYNRTSGDAENNKDLLNFTRVYGYRAIRSLKSNLTIGENFINSNIFNS 261 G+WR+R + +YN + + + + R I L+S LT+G+ + +IF+ Sbjct: 217 IGAWRLRDNTTWSYNSSDSSSGSKNKW-QHINTWLERDIIPLRSRLTLGDGYTQGDIFDG 275 Query: 262 WRYTGISLESDDRMLSPQLRGYAPQVTGIAETNARVVVKHQGRILYDSTVPAGPFAIQDL 321 + G L SDD ML RG+AP + GIA A+V +K G +Y+STVP GPF I D+ Sbjct: 276 INFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPPGPFTINDI 335 Query: 322 D-SSVRGKLDVEIIEQNGKTNKFQIDTAYVPYLTRPGQVRYKVVAGRSRDKLHNTEGPIF 380 + G L V I E +G T F + + VP L R G RY + AG R E P F Sbjct: 336 YAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYRSGNAQQEKPRF 395 Query: 381 GTTEAAFGLSNAWTMYGGTIFAGDYNSVALGVGRDMFAFGAVSADITQSYARLPDRGTMQ 440 + GL WT+YGGT A Y + G+G++M A GA+S D+TQ+ + LPD Sbjct: 396 FQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQANSTLPDDSQHD 455 Query: 441 GKSWRVSYSKRFDNLDADVTFAGYRFNERNYMTMQNYLDARYRD---------------- 484 G+S R Y+K + ++ GYR++ Y + +R Sbjct: 456 GQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGVIQVKPKF 515 Query: 485 ----DFTGKEKELYTVTFNKGLSEYNTSIGVQYNHQTYWDQSNSD-YYSINLNKYMDVFA 539 + ++ +T + L + ++ + +HQTYW SN D + LN A Sbjct: 516 TDYYNLAYNKRGKLQLTVTQQLGRTS-TLYLSGSHQTYWGTSNVDEQFQAGLNT-----A 569 Query: 540 VKNISLNLSASRSKY-YGKDNDV-FFARVSIPLENNRGFINYDGSRNS-----------G 586 ++I+ LS S +K + K D V+IP + + R++ G Sbjct: 570 FEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSMSHDLNG 629 Query: 587 NYTHNIGYFNTT-EDNLANYNLNVSTTYGDDMDSSSSFSGYYGRYTSIANINANATISNK 645 T+ G + T EDN +Y++ G D +S S+ N N + S+ Sbjct: 630 RMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIGYSHSDD 689 Query: 646 NTSSFGFSANGGLTITAKGAALHPDGFNGGTRLLVDTEGVAGVPVDGGR-VTTNNWGYGV 704 + +GG+ A G L T +LV G V+ V T+ GY V Sbjct: 690 IK-QLYYGVSGGVLAHANGVTLGQPL--NDTVVLVKAPGAKDAKVENQTGVRTDWRGYAV 746 Query: 705 VTDINSYYRNETTIDLTKLPNNIEATQAIVESSLTEGAIGYRKFEVLKGEKAFAIIRLAD 764 + Y N +D L +N++ A+ T GAI +F+ G K + + Sbjct: 747 LPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKLLMTLT-HN 805 Query: 765 NSYPPFGSIISNAKGRELGIISDDGFAWLTGINPNEEIRVSWGAE--QQCVA--KLP--N 818 N PFG+++++ + GI++D+G +L+G+ +++V WG E CVA +LP + Sbjct: 806 NKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCVANYQLPPES 865 Query: 819 KIEPSNKILLLC 830 + + ++ C Sbjct: 866 QQQLLTQLSAEC 877
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 28.8 bits (64), Expect = 0.007 Identities = 15/79 (18%), Positives = 28/79 (35%), Gaps = 10/79 (12%) Query: 57 QEDCPLGFMFLHDG-----HLEALFIDASARGLGIGKQLISHALTLHPN-----LSVDVN 106 E+ +G + + +E + + R G+G L+ A+ L ++ Sbjct: 72 LENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQ 131 Query: 107 EQNQQAVGFYQHMGFQISG 125 + N A FY F I Sbjct: 132 DINISACHFYAKHHFIIGA 150
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 30.9 bits (70), Expect = 0.004 Identities = 19/66 (28%), Positives = 25/66 (37%), Gaps = 14/66 (21%) Query: 120 AEAI-SLLRHGRVVIFSAGTGNPFFTT-------------DSAACLRGIEIEADVVLKAT 165 AE I L+ G +VI S G G P D A E+ AD+ + T Sbjct: 176 AETIKKLVERGVIVIASGGGGVPVILEDGEIKGVEAVIDKDLAGEKLAEEVNADIFMILT 235 Query: 166 KVDGVF 171 V+G Sbjct: 236 DVNGAA 241
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 210 bits (537), Expect = 6e-63 Identities = 108/453 (23%), Positives = 210/453 (46%), Gaps = 46/453 (10%) Query: 12 KRRTFAIISHPDAGKTTITEKVLLFGQAIQRAGTVKGRGSNQHAKSDWMEMEKQRGISIT 71 K +++H DAGKTT+TE +L AI G+V ++D +E+QRGI+I Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSV----DKGTTRTDNTLLERQRGITIQ 57 Query: 72 TSVMQFPYADCLVNLLDTPGHEDFSEDTYRTLTAVDCCLMVIDSSKGVEDRTRKLMEVTR 131 T + F + + VN++DTPGH DF + YR+L+ +D +++I + GV+ +TR L R Sbjct: 58 TGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALR 117 Query: 132 LRDTPILTFMNKLDRDIRDPMELMDEVETELKIACSPVTWPIGCGKLFKGVYHILRDETY 191 P + F+NK+D++ D + +++ +L +++ + Sbjct: 118 KMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEI------------------VIKQKVE 159 Query: 192 LYQTGQGHTIQNSRVIKGLDNPELDEAIGDDLAVQLRDELELVLGASHEFDHEAFLAGEL 251 LY S + DDL + L + + F L Sbjct: 160 LYPNMCVTNFTESEQWDTVIEGN------DDLLEKYMSGKSLEALELEQEESIRFHNCSL 213 Query: 252 TPVFFGTALGNFGVNHMLDGLVKWAPAPMPR-QTDMREVTAAEETFTGFVFKIQANMDPK 310 PV+ G+A N G++++++ + + R Q+++ G VFKI+ K Sbjct: 214 FPVYHGSAKNNIGIDNLIEVITNKFYSSTHRGQSELC----------GKVFKIE--YSEK 261 Query: 311 HRDRVAFLRVVSGMYDKGMKLHQVRTKKDVVISDALTFMAGDRSHVEHAYPGDIIGLHNH 370 R R+A++R+ SG+ + ++ K+ + I++ T + G+ ++ AY G+I+ L N Sbjct: 262 -RQRLAYIRLYSGVLHLRDSV-RISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNE 319 Query: 371 GTIQIGDTFTQGEMLKFTGIPNFA-PELFRRIRLRDPLKQKQLLKGLVQLSEEG-AVQVF 428 +++ ++L P L + P +++ LL L+++S+ ++ + Sbjct: 320 F-LKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYY 378 Query: 429 RPLANNDLIVGAVGVLQFDVVVARLKGEYNVEA 461 A +++I+ +G +Q +V A L+ +Y+VE Sbjct: 379 VDSATHEIILSFLGKVQMEVTCALLQEKYHVEI 411
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 33.9 bits (77), Expect = 0.002 Identities = 22/133 (16%), Positives = 44/133 (33%), Gaps = 4/133 (3%) Query: 142 LRCHFLGQKALTPLYQAVDERVRQLFPAAAMSRLSAMLTAVPSLASTGEVLKLVDAIVAM 201 + LY E+ Q ++ + + VPS+ S E + VD Sbjct: 967 WKYKLRNVNGRYDLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVP 1026 Query: 202 LEDESRPP-QDESDADSGNDIGQDASNDSNNSSDSQTPEADSSAMGDAAETGDSDNSDQA 260 + P E+ A++ Q++ N D+ A + + A++ N+ Sbjct: 1027 PPAPATPSETTETVAENSK---QESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTN 1083 Query: 261 DNLRQALEASAAQ 273 + + E Q Sbjct: 1084 EVAQSGSETKETQ 1096
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.8 bits (69), Expect = 0.026 Identities = 24/123 (19%), Positives = 42/123 (34%), Gaps = 13/123 (10%) Query: 532 AELSRLDWLEL-DPANPTRKARTVTTNDGVQEQGLLLKVSISKRLIALIDISKQDTE--- 587 E++R+D + PA T T T + +++ ++ + + E Sbjct: 1015 EEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKS 1074 Query: 588 --PATAIQNEEALQRPSRTKTTNAQAKEPAT-------RAERKQKPIAPNAKSSTDPKYV 638 A NE A +T + KE AT + E ++ P S PK Sbjct: 1075 NVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQE 1134 Query: 639 QRQ 641 Q + Sbjct: 1135 QSE 1137
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 44.9 bits (106), Expect = 1e-08 Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 2/96 (2%) Query: 47 IDNIMVGF-AITQLILDEATLFNIAIHPDYQGKGYGKALLLELIDNIERKDIATLWLEVR 105 ++N +G I A + +IA+ DY+ KG G ALL + I+ + L LE + Sbjct: 72 LENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQ 131 Query: 106 ESNQKASNLYESIGFNSVSV-RKNYYPTATGKEDAI 140 + N A + Y F +V Y T E AI Sbjct: 132 DINISACHFYAKHHFIIGAVDTMLYSNFPTANEIAI 167
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 50.3 bits (120), Expect = 3e-10 Identities = 22/107 (20%), Positives = 41/107 (38%), Gaps = 8/107 (7%) Query: 65 ERGAPFWGVFEDDKLVAATSVDPQWRGQDNTLLQLSFLHISHQQRGQGLARILFDYCVEY 124 E G + + ++ + + W N + + ++ R +G+ L +E+ Sbjct: 62 EEGKAAFLYYLENNCIGRIKIRSNW----NGYALIEDIAVAKDYRKKGVGTALLHKAIEW 117 Query: 125 AKQKGASGLYISSTPSEN--SVNFYQHMGCRLIDVPDTELYEREPED 169 AK+ GL + T N + +FY + V DT LY P Sbjct: 118 AKENHFCGLML-ETQDINISACHFYAKHHFIIGAV-DTMLYSNFPTA 162
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 89.0 bits (220), Expect = 2e-20 Identities = 86/360 (23%), Positives = 167/360 (46%), Gaps = 34/360 (9%) Query: 356 NSLSGMSLLTFLLSKTRELTLKVMLHRSESEQKLFNEMQEVTEKSLKDKVEEQKSLIKKQ 415 ++LS ++ LT L++ E+ K +++ LFN +QE + ++ K E + +K Sbjct: 248 DNLSNVARLTMLMAMFIEIVGKNTEESLQNDLALFNALQEGRQAEMEKKSAEFQEETRKA 307 Query: 416 EEIQFWAGIGLKILGGLLTLVAGVSSIFTAGSSMVLIGVATTLFVADAGLTIADEVYQSI 475 EE G K+LG LLT+V+ V+++FT G+S+ L V + V ADE+ ++ Sbjct: 308 EETNRIMGCIGKVLGALLTIVSVVAAVFTGGASLALAAVGLAVMV-------ADEIVKAA 360 Query: 476 HNKSFMDEIMQPISDAVMEAIDKVSDFLVSLVNSSLDGLKELGLDKKIIEEMKNSIQDKL 535 SF+ + + PI + V++ + ++ + + +L+G LG+DKK Sbjct: 361 TGVSFIQQALNPIMEHVLKPLMEL---IGKAITKALEG---LGVDKK-----------TA 403 Query: 536 KMATKILVTVVLFVAATALSFVIGPAMKG----ISDAVNKISNQQIRQILKKVLNDGLEA 591 +MA I+ +V +A A+ V+ KG + +A++K+ + I++++ VL L Sbjct: 404 EMAGSIVGAIVAAIAMVAVIVVVAVVGKGAAAKLGNALSKMMGETIKKLVPNVLKQ-LAQ 462 Query: 592 VLGKMIKDI---IIKALEEALEKIDKQLAKEISKKASIMLNRTVVASKLTNSAATNTVNI 648 K+ I L K+ Q + LN+ + ++TN+AA + + Sbjct: 463 NGSKLFTQGMQRITSGLGNVGSKMGLQTNALSKELVGNTLNKVALGMEVTNTAAQSAGGV 522 Query: 649 YGSVIASKIIQSIAGSKKLTAVLDIIQKLMDKIMETYHENIDSITDILKNLSDKSSVSNK 708 V +++A +D IQ+ + + +E + EN ++ K +S S+V Sbjct: 523 AEGVFIKNASEALADFMLARFAMDQIQQWLKQSVEIFGENQKVTAELQKAMS--SAVQQN 580
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 112 bits (281), Expect = 4e-34 Identities = 41/143 (28%), Positives = 71/143 (49%), Gaps = 4/143 (2%) Query: 19 IVSIVQNGASIKDESEIPDGFMEGIYSFAYDFYQKGKLDEAEAIFKFLCLYDFYNVDYIM 78 + S ++ G +I +EI +E +YS A++ YQ GK ++A +F+ LC+ D Y+ + + Sbjct: 15 MESFLKGGGTIAMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFL 74 Query: 79 GLAAVNQLKKQYQAAIDLYALAYLNAKNDYRPVFYAGQCNLSIGEKEKAKYCFH----QV 134 GL A Q QY AI Y+ + + R F+A +C L GE +A+ + Sbjct: 75 GLGACRQAMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQELI 134 Query: 135 AQNINDQTIKEKANSYLELLKDI 157 A + + + +S LE +K Sbjct: 135 ADKTEFKELSTRVSSMLEAIKLK 157
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 265 bits (679), Expect = 5e-89 Identities = 108/345 (31%), Positives = 182/345 (52%), Gaps = 5/345 (1%) Query: 2 AEKTEKPTQKKLDDSAKKGQSFKSKELVSGLVYFIGVIYLF-----NQVKLDEFNQFYQS 56 EKTE+PT KK+ D+ KKGQ KSKE+VS + L + Sbjct: 3 GEKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLMLIPAE 62 Query: 57 LLLHPTGISLKSYVEVISKLFFDIVLPIIIVTFLSGAIPSLFSSHFKLATEAIKIDFNHI 116 P +L V+ + FF + P++ V L + F ++ EAIK D I Sbjct: 63 QSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDIKKI 122 Query: 117 NPISGFKKIFSIRTIKDFLKTILFIIIFLITCYVFMILHMGEVVILYRADLEGVIDKWCS 176 NPI G K+IFSI+++ +FLK+IL +++ I ++ + ++ ++ L +E + Sbjct: 123 NPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLLGQ 182 Query: 177 LVVSFIFIFFILSIPILILNIIADFFLFIKDMMMEKHEVKQEHKNMEGNPEIKSVRRQLH 236 ++ + I + + I I + +++ +IK++ M K E+K+E+K MEG+PEIKS RRQ H Sbjct: 183 ILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKRRQFH 242 Query: 237 QELLDEPMKRVIRDSSAVIVNPTHVAVGIYFDPDNGIMPIVSLSCTNAKALAVKAYAKKV 296 QE+ M+ ++ SS V+ NPTH+A+GI + +P+V+ T+A+ V+ A++ Sbjct: 243 QEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIAEEE 302 Query: 297 GTPVIRYPELARKLHHKYHLFEVIIDQDLLDVMDVLIWLKRVEIE 341 G P+++ LAR L+ + I + + +VL WL+R IE Sbjct: 303 GVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQNIE 347
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 112 bits (282), Expect = 4e-32 Identities = 42/226 (18%), Positives = 92/226 (40%), Gaps = 4/226 (1%) Query: 10 SYLIDIFLLIARLFPIFMFIPFLNSRVLNSQLLKYIIIFYIALGIKPSITI--TGVLRET 67 S+L F + R+ + P L+ R + + +K + I I PS+ V Sbjct: 11 SWLNLYFWPLLRVLALISTAPILSERSV-PKRVKLGLAMMITFAIAPSLPANDVPVFSFF 69 Query: 68 WAIVLISELIIGLVIGLLLATPFWIASAFGEFVDNQRGASIGDTINPTTGIESSEFASLT 127 + + +++IG+ +G + F GE + Q G S ++P + + A + Sbjct: 70 ALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHLNMPVLARIM 129 Query: 128 GLFCMAYFLATGGLVVLMSTIKESYDVFPIGYINKN-IGYDFIGHWLNDMVKVAIILVSP 186 + + FL G + L+S + +++ PIG N + + + + ++L P Sbjct: 130 DMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLIFLNGLMLALP 189 Query: 187 VLITMFLSEVALGVYSLFCPQLNAFSLSLCIKGIIAFLVLLLFFTS 232 ++ + +ALG+ + PQL+ F + + + ++ Sbjct: 190 LITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPL 235
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 58.6 bits (142), Expect = 2e-15 Identities = 45/82 (54%), Positives = 66/82 (80%) Query: 2 DMVYAANKAIYLIILLSAAPIAIATFIGLLIGLLQTITQIQEQTLPFGVKLVGVFVCLLM 61 D+V+A NKA+YL+++LS P +AT IGLL+GL QT+TQ+QEQTLPFG+KL+GV +CL + Sbjct: 3 DLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLFL 62 Query: 62 MMGWMGDKLLIYAKEMLTIGLA 83 + GW G+ LL Y ++++ + LA Sbjct: 63 LSGWYGEVLLSYGRQVIFLALA 84
>TYPE3IMPPROT#Type III secretion system inner membrane P protein family signature. Length = 224 Score = 220 bits (561), Expect = 7e-75 Identities = 125/222 (56%), Positives = 161/222 (72%), Gaps = 7/222 (3%) Query: 1 MESSTQLILILALATLAPFIIAAGTCYLKFSIVLVMTRNALGVQQVPSNMVLNAIALMMA 60 M + LI +LA +TL PFIIA+GTC++KFSIV VM RNALG+QQ+PSNM LN +AL+++ Sbjct: 1 MGNDISLIALLAFSTLLPFIIASGTCFVKFSIVFVMVRNALGLQQIPSNMTLNGVALLLS 60 Query: 61 LFVMTPITKNICYYIIENKVDMSSPDAIESFSNEALGDYKKYLYHYSDPDLLAFFEQAQE 120 +FVM PI + Y + V + ++ +E L Y+ YL YSD +L+ FFE AQ Sbjct: 61 MFVMWPIMHDAYVYFEDEDVTFNDISSLSKHVDEGLDGYRDYLIKYSDRELVQFFENAQL 120 Query: 121 NRP------NSDGDKENIE-NSLLSLLPAYALSEIKSAFIIGFYLYLPFIVIDLVVSCIL 173 R DK+ IE S+ +LLPAYALSEIKSAF IGFYLYLPF+V+DLVVS +L Sbjct: 121 KRQYGEETETVKRDKDEIEKPSIFALLPAYALSEIKSAFKIGFYLYLPFVVVDLVVSSVL 180 Query: 174 LALGMMMMSPITLSVPLKLILFIAMDGWGLLSKGLINQYLDL 215 LALGMMMMSP+T+S P+KL+LF+A+DGW LLSKGLI QY+D+ Sbjct: 181 LALGMMMMSPVTISTPIKLVLFVALDGWTLLSKGLILQYMDI 222
>TYPE3OMOPROT#Type III secretion system outer membrane O protein family signature. Length = 303 Score = 87.8 bits (217), Expect = 4e-22 Identities = 50/155 (32%), Positives = 76/155 (49%), Gaps = 16/155 (10%) Query: 151 FILGYSKISLSLLKTILPGDVLLIDDIHFSFNVGDKKYFYFSWDEGNCV--TLDAIVENS 208 F++G S SLL I GDVLLI KK +F+ EG + TLD I Sbjct: 154 FVIGSSDTQRSLLGRIGIGDVLLIRTSRAEVYCYAKKLGHFNRVEGGIIVETLD-IQHIE 212 Query: 209 EENEEDEQNDAIIEDSIDLAQSLDLNSIGAIPITISFLLANKTLSIDQLEELAPGKKFIL 268 EEN E + + LN + P+ + F+L K +++ +LE + + L Sbjct: 213 EENNTTETAETL----------PGLNQL---PVKLEFVLYRKNVTLAELEAMGQQQLLSL 259 Query: 269 PDNAIRHINILANGKAIAQGELIKIKDMLAVEINK 303 P NA ++ I+ANG + GEL+++ D L VEI++ Sbjct: 260 PTNAELNVEIMANGVLLGNGELVQMNDTLGVEIHE 294
>SSPAKPROTEIN#Invasion protein B family signature. Length = 133 Score = 56.5 bits (136), Expect = 3e-13 Identities = 33/126 (26%), Positives = 58/126 (46%), Gaps = 5/126 (3%) Query: 4 DLASLLMDAMNVIGRNDLFSGGKSIDNHSTITISLGDMPDINLLVVDEVPMIWSVLCDYD 63 +L L+ D++ IG +D+HS ITISL MP IN+ +V+E M+W+ Sbjct: 5 NLVQLVRDSLFTIGCPPSIITD--LDSHSAITISLDSMPAINIALVNEQVMLWANFDAPS 62 Query: 64 EKLLTQISAELLLDSINNQTESFYPGQPALVRIEDS-LELRASFMPIALQNGESMARAID 122 + L + +L + N S+ + + D L+LR + +G A + Sbjct: 63 DVKLQSSAYNILNLMLMNF--SYSINELVELHRSDEYLQLRVVIKDDYVHDGIVFAEILH 120 Query: 123 DYFQIM 128 +++Q M Sbjct: 121 EFYQRM 126
>INVEPROTEIN#Salmonella/Shigella invasion protein E (InvE) signature. Length = 372 Score = 128 bits (322), Expect = 5e-36 Identities = 92/338 (27%), Positives = 165/338 (48%), Gaps = 5/338 (1%) Query: 24 QDIEYKQPQINESENYQNQ-LIEISDDMSMVATLFSQRLGKLLDKKANKGQEALYIAEDG 82 Q E +Q + S + Q ++ +D+MS F R K +N + ED Sbjct: 31 QQAEIQQAAEDSSPGAEVQKFVQSTDEMSAALAQFRNRR-DYEKKSSNLSNSFERVLEDE 89 Query: 83 ADEKLDKVMLQFRKSGRSLQELLQYLRKMFPDPSDLVMVLRELLRKKKLGAQLDAGIENE 142 A K +++ G +L++ L+ R +FPDPSDLV+VLRELLR+K L + +E+ Sbjct: 90 ALPKAKQILKLISVHGGALEDFLRQARSLFPDPSDLVLVLRELLRRKDLEEIVRKKLESL 149 Query: 143 INRLLAGEEGKQIKAGINIALQAKAFAKLLCLDASVLRDLYRSYIILDIEPIYFFKMWIE 202 + + + K +KAGIN AL+A+ F K L L +LR YR +I + + + WI Sbjct: 150 LKHVEEQTDPKTLKAGINCALKARLFGKTLSLKPGLLRASYRQFIQSESHEVEIYSDWIA 209 Query: 203 KYDIKKCSIILNFLTQSLICDMKSLMPSCSQSSEFGYLLEKVNKLRLLYSFIEMNIENLV 262 Y ++ ++L+F+ SL+ D+ + SCS+ EFG LL ++ +L++L S + + L+ Sbjct: 210 SYGYQRRLVVLDFIEGSLLTDIDANDASCSR-LEFGQLLRRLTQLKMLRSADLLFVSTLL 268 Query: 263 KEDL-KSFIKEDDFYQLTINGMIS-PEQMEKYLISLMDNQWKGYFIKIKMRLLQQLKTMF 320 K+F E+ + L + ++ P +++ L ++ K LQ + Sbjct: 269 SYSFTKAFNAEESSWLLLMLSLLQQPHEVDSLLADIIGLNALLLSHKEHASFLQIFYQVC 328 Query: 321 NKYPELLYLSDDFRNECQIMIQKIIDNYIKKEQYQLRK 358 P L+ + ++ E + ++ + D K E + R+ Sbjct: 329 KAIPSSLFYEEYWQEELLMALRSMTDIAYKHEMAEQRR 366
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 371 bits (955), Expect = e-124 Identities = 153/525 (29%), Positives = 267/525 (50%), Gaps = 57/525 (10%) Query: 37 KKPDVFVAVNTHIEQFFLVLSDKLNKPFILSSAVKKERISGKFDISSPEDAFELMVKRLS 96 P V+VA + + ++S + ++SG+F+ +P+D + + + Sbjct: 33 PIPYVYVAKGESLRDLLTDFGANYDATVVVSDKIND-KVSGQFEHDNPQDFLQHIASLYN 91 Query: 97 LLYFNDGESIYIYRDNEIQQQLFQVKNISLSKLKEYLQDVGLYDLRYPLRAGHDQRTFYL 156 L+++ DG +YI++++E+ +L +++ ++LK+ LQ G+++ R+ R R Y+ Sbjct: 92 LVWYYDGNVLYIFKNSEVASRLIRLQESEAAELKQALQRSGIWEPRFGWRPDASNRLVYV 151 Query: 157 SGPPIYISLVKAAAELLDNDVQEKINENINNQVPTGSSRYGDEFVQIFPLKNTFVQDRTY 216 SGPP Y+ LV+ A L+ Q + S + G ++IFPLK DRT Sbjct: 152 SGPPRYLELVEQTAAALEQQTQIR------------SEKTGALAIEIFPLKYASASDRTI 199 Query: 217 ILRDEKVVLPGITTVLQQLFMPSGEKEKTVRRAREIIEDNDKYQDDKITNDIQDTHSPII 276 RD++V PG+ T+LQ++ + ++ TV R ++ D Sbjct: 200 HYRDDEVAAPGVATILQRVLSDATIQQVTVDNQRIPQAATRASAQARVEAD--------- 250 Query: 277 TQMGKYNVELVPLPGSNSLLVKTSREGLALVSSLISQLDKPKRQVELSLWIIDISKSKAD 336 P N+++V+ S E + + LI LDKP ++E++L I+DI+ + Sbjct: 251 -------------PSLNAIIVRDSPERMPMYQRLIHALDKPSARIEVALSIVDINADQLT 297 Query: 337 SLGVNWQG--SYGSGKNTFFFNTASLSAVS--GFS-----------FLSKIKALSEEGEA 381 LGV+W+ G+ T S ++ G L+++ L EG A Sbjct: 298 ELGVDWRVGIRTGNNHQVVIKTTGDQSNIASNGALGSLVDARGLDYLLARVNLLENEGSA 357 Query: 382 KMVSRPILLTQENTPAIFDNNTTFYTQIKGERVASLESTTFGTMISVLPRIS--NTNQEI 439 ++VSRP LLTQEN A+ D++ T+Y ++ G+ VA L+ T+GTM+ + PR+ EI Sbjct: 358 QVVSRPTLLTQENAQAVIDHSETYYVKVTGKEVAELKGITYGTMLRMTPRVLTQGDKSEI 417 Query: 440 EMIINLEDGAEKKSDDEDREEGIEKLPVINRTNISTVARVSEGGSLLIGGYTREDNIKAE 499 + +++EDG +K GIE +P I+RT + TVARV G SL+IGG R++ A Sbjct: 418 SLNLHIEDGNQK-----PNSSGIEGIPTISRTVVDTVARVGHGQSLIIGGIYRDELSVAL 472 Query: 500 NKIPFLSAIPLVGRAFSYQSDNNKKMVRIFMLQPRLLDKTDTHGL 544 +K+P L IP +G F +S+ ++ VR+F+++PR++D+ H L Sbjct: 473 SKVPLLGDIPYIGALFRRKSELTRRTVRLFIIEPRIIDEGIAHHL 517
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 46.9 bits (111), Expect = 4e-08 Identities = 46/188 (24%), Positives = 76/188 (40%), Gaps = 13/188 (6%) Query: 26 LLTNLSQRQATEIQAVLQKHQITSTRTALGKGLFEISVKKENIGIAIQILEEYQLPTISR 85 L +NLS + I A L + I G I V + + L + LP Sbjct: 53 LFSNLSDQDGGAIVAQLTQMNIPYR---FANGSGAIEVPADKVHELRLRLAQQGLPKGGA 109 Query: 86 IEITQLFPSDALVSSPQAEKARLISAIEQRLEQSLLTIDHLIDARVHVSYPLSSN-DRIT 144 + +L + S +E+ A+E L +++ T+ + ARVH++ P S R Sbjct: 110 VGF-ELLDQEKFGISQFSEQVNYQRALEGELARTIETLGPVKSARVHLAMPKPSLFVREQ 168 Query: 145 PTPHASALVFYEDGM-IDSDQLSDDVRAFIHNAFNDMDESNITV------LLYPRNINKF 197 +P AS V E G +D Q+S V + +A + N+T+ LL N + Sbjct: 169 KSPSASVTVTLEPGRALDEGQIS-AVVHLVSSAVAGLPPGNVTLVDQSGHLLTQSNTSGR 227 Query: 198 TILNNQLH 205 + + QL Sbjct: 228 DLNDAQLK 235
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 28.4 bits (63), Expect = 0.008 Identities = 6/22 (27%), Positives = 15/22 (68%) Query: 10 RALTVGEVAKRSGVAISTLHFY 31 + ++GE+AK +GV ++++ Sbjct: 30 SSTSLGEIAKAAGVTRGAIYWH 51
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 38.7 bits (90), Expect = 3e-05 Identities = 23/120 (19%), Positives = 42/120 (35%), Gaps = 1/120 (0%) Query: 43 VALATAQSAELPNTMHGVGELEAA-RQVYLAAETNGRIATIHFASGQTVTAGQILVKLND 101 +A + ++ G+L + R + N + I G++V G +L+KL Sbjct: 70 IAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTA 129 Query: 102 EPEQAELLRLQAQLTNAEKLYSRTRQLYSKNVAAAAQLDSTLSERDMIVASIREVKARIA 161 +A+ L+ Q+ L A +R + L E S EV + Sbjct: 130 LGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTS 189 Score = 29.0 bits (65), Expect = 0.030 Identities = 40/253 (15%), Positives = 72/253 (28%), Gaps = 75/253 (29%) Query: 98 KLNDEPEQAELLRLQAQLTNAEKLY-------SRTRQLYSKNVAAAAQLDSTLSERDMIV 150 +LN + ++AE L + A++ E L L K A + ++ V Sbjct: 206 ELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAV 265 Query: 151 ASIREVKARIAQ------------------------------------------------ 162 +R K+++ Q Sbjct: 266 NELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQ 325 Query: 163 --KTIKAPFDGIVGIKLVH-EGQYLNAEERVASLV-DASHLKLNFSLDEQVAPQLSTHQP 218 I+AP V VH EG + E + +V + L++ + + ++ Q Sbjct: 326 QASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQN 385 Query: 219 INIAVDAYPNQTFTGSLNAIDPLIGPSRTVQ--------------VQAILPNTDN-KLKA 263 I V+A+P T G L I + N L + Sbjct: 386 AIIKVEAFP-YTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCLSTGNKNIPLSS 444 Query: 264 GMFARVQVTSPTR 276 GM ++ + R Sbjct: 445 GMAVTAEIKTGMR 457
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 802 bits (2073), Expect = 0.0 Identities = 304/1029 (29%), Positives = 538/1029 (52%), Gaps = 29/1029 (2%) Query: 5 DIFVRRPVLALVVSTLIFLLGAFAFSKLPIRQYPMLQNSTITIATDYPGASSELMQGFVT 64 + F+RRP+ A V++ ++ + GA A +LP+ QYP + ++++ +YPGA ++ +Q VT Sbjct: 3 NFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVT 62 Query: 65 QPITQAVSSVEGVDYISSSSVQ-GKSFVTVRMELNRDPTQALTQVMAKVNQVRYKLPEQA 123 Q I Q ++ ++ + Y+SS+S G +T+ + DP A QV K+ LP++ Sbjct: 63 QVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEV 122 Query: 124 YDPVIELSSGESTAVAYVGFSSE--QISIPELTDYLSRVVEPMFSSINGVAKVQVFGGQQ 181 I + S+ + GF S+ + +++DY++ V+ S +NGV VQ+FG Q Sbjct: 123 QQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQ- 181 Query: 182 LAMRVWLDTDKLAGRNLTASDVADAIRRNNYQAAPGKVEGEFVI------ANVYVNTDLT 235 AMR+WLD D L LT DV + ++ N Q A G++ G + A++ T Sbjct: 182 YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK 241 Query: 236 NVEEFKDMVIH-NDGHNLIRLRDIGTVELGAAATETSGIMNGKKAVFLGLFPTPTGNPLI 294 N EEF + + N +++RL+D+ VELG +NGK A LG+ N L Sbjct: 242 NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALD 301 Query: 295 IVDGIRENLTDIEKTLPPGVNVELAFETSRFIKASIDQVVQTLIEAILIVIAVIYLCLGS 354 I+ L +++ P G+ V ++T+ F++ SI +VV+TL EAI++V V+YL L + Sbjct: 302 TAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQN 361 Query: 355 LRSVIIPVLAIPLSMLGAAGLMLAFGFSINLLTLLAMVLAIGLVVDDAIVVVENVHRHI- 413 +R+ +IP +A+P+ +LG ++ AFG+SIN LT+ MVLAIGL+VDDAIVVVENV R + Sbjct: 362 MRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 414 EEGLSPVQAALVGAREVAGPVIAMTITLAAVYAPIGLMSGLTGALFKEFAITLAGSVIVS 473 E+ L P +A ++ G ++ + + L+AV+ P+ G TGA++++F+IT+ ++ +S Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 474 GIVALTLSPVMSSLMLKP-----KENEGRMAKIAEYTFDKLAYYYSYLLNFSLTHRWLTV 528 +VAL L+P + + +LKP EN+G TFD +Y+ + L + Sbjct: 482 VLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYL 541 Query: 529 VFAFAVFVSLPFLYSQTKQELAPLEDQASVLTAVKAPQHANLAYAEHFNQKLDDIYMSLP 588 + + + L+ + P EDQ LT ++ P A + ++ D Y+ Sbjct: 542 LIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNE 601 Query: 589 ETD------STWIINGTDGPSASFGGINFDGWKGRDRNANQIQAD---LQNRVADVEGSS 639 + + +A ++ W+ R+ + N +A + + + Sbjct: 602 KANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGF 661 Query: 640 IFAFQLA--SLPGSVGGLPVQMVLRSPLGYPVLFDTMEEIKQQARESGLFVV-VDSDLDY 696 + F + G+ G +++ ++ LG+ L ++ A + +V V + Sbjct: 662 VIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLE 721 Query: 697 NNPVVQITIDRAKANTLGIRMQDIGESLSLLVGEHYINRFGMDGRSYDVIPQSIRQQRLT 756 + ++ +D+ KA LG+ + DI +++S +G Y+N F GR + Q+ + R+ Sbjct: 722 DTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRML 781 Query: 757 PAALAGHYIRTQDNLLIPLSTVVNITTQVEPNKLTQFNQQNAAIFQAIPAPGVTMGQAVA 816 P + Y+R+ + ++P S +L ++N + Q APG + G A+A Sbjct: 782 PEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMA 841 Query: 817 FLENVANSLPAGFSHDWQSDARQFTQEGNTLVFAFIAALIIIYLVLAAQYESLVDPLIIL 876 +EN+A+ LPAG +DW + Q GN + ++++L LAA YES P+ ++ Sbjct: 842 LMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVM 901 Query: 877 ITVPLSICGALVPLALGMVTLNIYTQIGLVTLIGLISKHGILMVEFANELQVHKNLNRRE 936 + VPL I G L+ L ++Y +GL+T IGL +K+ IL+VEFA +L + E Sbjct: 902 LVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVE 961 Query: 937 AIIEAAKIRLRPVLMTTAAMVIGLIPLLFASGAGANSRYGLGLIIVSGMLVGTLFTLFVL 996 A + A ++RLRP+LMT+ A ++G++PL ++GAG+ ++ +G+ ++ GM+ TL +F + Sbjct: 962 ATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFV 1021 Query: 997 PTMYSFLAR 1005 P + + R Sbjct: 1022 PVFFVVIRR 1030
>BACYPHPHTASE#Salmonella/Yersinia modular tyrosine phosphatase signature. Length = 468 Score = 70.6 bits (172), Expect = 2e-15 Identities = 76/315 (24%), Positives = 124/315 (39%), Gaps = 64/315 (20%) Query: 71 TEVLNKLYYNENSPQYDENNYQCVPNSRYRVRYCKKTLIESNGVLLPTNNVSVKNSPYTT 130 T + N L N P+Y + N ++ C++T + ++ L N + V N+ T Sbjct: 202 TTLRNTLAPATNDPRYLQACGGEKLNRFRDIQCCRQTAVRAD---LNANYIQVGNT--RT 256 Query: 131 IASQYPLNDKESLKHYFNMLFDNDIKTVYVLASNKDIKWDFSKPDSEYDKSNSKQKGFKY 190 IA QYPL L+ +F ML +N + VLAS Sbjct: 257 IACQYPLQS--QLESHFRMLAENRTPVLAVLAS--------------------------- 287 Query: 191 FREDFYSDNIESRHFNKWDFSRFKIKGKNGKFIENKNGDNEVLLNERSLDCKVYINKLTK 250 S I ++ F D+ F+ G G +V L + + +Y LT Sbjct: 288 ------SSEIANQRFGMPDY--FRQSGTYGSITVESKMTQQVGLGD-GIMADMY--TLTI 336 Query: 251 KGCDEKK-NIKFVHIYNWRDHTAIDATKLKNTIDLI--------------GKELTINPTK 295 + +K ++ VH+ NW D TA+ + K L+ G + +K Sbjct: 337 REAGQKTISVPVVHVGNWPDQTAVSSEVTKALASLVDQTAETKRNMYESKGSSAVGDDSK 396 Query: 296 ENIAVHCLAGLGRTGEFIALMEMMKMIEAGNTKTKSLESILVHLRENRSREVLKRKSQVD 355 +HC AG+GRT + I M M S+E ++ +R R+ ++++ Q+D Sbjct: 397 LRPVIHCRAGVGRTAQLIGAMCM----NDSRNSQLSVEDMVSQMRVQRNGIMVQKDEQLD 452 Query: 356 ELIKFAINHNIPLVN 370 LIK A PL+N Sbjct: 453 VLIKLAEGQGRPLLN 467
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 464 bits (1195), Expect = e-167 Identities = 144/354 (40%), Positives = 213/354 (60%), Gaps = 5/354 (1%) Query: 2 KAATAVIDRRALRHNFQHVRDYAPHSHLIAVVKANAYGHGLLETAYTLMDDADCFGVARI 61 + A +D +AL+ N VR A H+ + +VVKANAYGHG+ + D F + + Sbjct: 3 RPIQASLDLQALKQNLSIVRQAATHARVWSVVKANAYGHGIERIWSAI-GATDGFALLNL 61 Query: 62 GEALTLRSGGIVKPILLLEGFFDAVDLPILVVNHIETVVHSEEQLEALENADLEEPVKVW 121 EA+TLR G PIL+LEGFF A DL I + + T VHS QL+AL+NA L+ P+ ++ Sbjct: 62 EEAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQNARLKAPLDIY 121 Query: 122 MKLDTGMHRLGVRPEEAEAFYQRLCACKNVQQPVNLVSHFSRADEPDIPEVTQNQIQLFQ 181 +K+++GM+RLG +P+ +Q+L A NV + + L+SHF+ A+ PD + + Sbjct: 122 LKVNSGMNRLGFQPDRVLTVWQQLRAMANVGE-MTLMSHFAEAEHPD---GISGAMARIE 177 Query: 182 AFIQDKAGDKSIAASAGILFWPQVHYQWVRPGIITYGISPTGDNRTGKDFGLTPAMTLKT 241 + +S++ SA L+ P+ H+ WVRPGII YG SP+G R + GL P MTL + Sbjct: 178 QAAEGLECRRSLSNSAATLWHPEAHFDWVRPGIILYGASPSGQWRDIANTGLRPVMTLSS 237 Query: 242 SLIAVRKHKAGEPVGYGGTWVSEKDTYLGVIAIGYGDGYPRSAPSGTPVWINGRKVPIVG 301 +I V+ KAGE VGYGG + + + +G++A GY DGYPR AP+GTPV ++G + VG Sbjct: 238 EIIGVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAPTGTPVLVDGVRTMTVG 297 Query: 302 RVSMDMISVDLGSELIDRVGDEAILWGDVLPVEEIAKYSGISAYELITKLTSRV 355 VSMDM++VDL +G LWG + ++++A +G YEL+ L RV Sbjct: 298 TVSMDMLAVDLTPCPQAGIGTPVELWGKEIKIDDVAAAAGTVGYELMCALALRV 351
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 32.5 bits (74), Expect = 0.002 Identities = 41/249 (16%), Positives = 90/249 (36%), Gaps = 27/249 (10%) Query: 83 SDIKRTIISRYFTVFSLSYI-IGVIIIFLVTSYLIEIVFDSQIYIIIFLGFFLSPLMIWF 141 ++ +T+ VF + Y+ + + L+ + + +V I+ G+ ++ + F Sbjct: 338 HEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSIN-TLTMF 396 Query: 142 FMYFLIKFYVSCSIHYLNNFSLYSREKK--KFNISYIIVNEV----FLSLLVNFPIVFPL 195 M I V +I + N E K + ++++ +V + P+ Sbjct: 397 GMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPM 456 Query: 196 QNSATFSLEQGYLNIEFIVALIILLYSVLFVMLFLSKASKINYLMGMIICYSFEEDFAEV 255 A F G + +F + ++ + + V L L+ A L ++ E Sbjct: 457 ---AFFGGSTGAIYRQFSITIVSAMALSVLVALILTPA-----LCATLLKPVSAEHHEN- 507 Query: 256 KKRGLFCRVLWFL-ILIPLGTLLLCLLFYLLNIKENFFLIYSVSLSLVIYLYFIERRNKL 314 K G F WF + +L + LIY++ ++ ++ L+ +L Sbjct: 508 -KGGFF---GWFNTTFDHSVNHYTNSVGKILGSTGRYLLIYALIVAGMVVLF-----LRL 558 Query: 315 YQEFILAFD 323 F+ D Sbjct: 559 PSSFLPEED 567
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 115 bits (289), Expect = 3e-33 Identities = 64/251 (25%), Positives = 116/251 (46%), Gaps = 10/251 (3%) Query: 7 LKNKNVIVTGANGDIGIAICQKYLEQQCHVYALYHQNRNNLDKLKKESEYCQRLHILQCD 66 ++ K +TGA IG A+ + Q H+ A+ + + + D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 67 INNDKSIHDFLDKLKAYANAIHILINNAGVIKDELFSAINISEFEYVIKTNLLGTCQFTK 126 + + +I + +++ I IL+N AGV++ L +++ E+E N G ++ Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 127 QLLLLLRSAEKATIINVASIAGIVPSIGQSNYSAAKAGIIGFTHTLAAELAGKGIRVNAV 186 + + +I+ V S VP + Y+++KA + FT L ELA IR N V Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 187 APGMIESDMVKKV------SRQVVR----HIKSVIPLQRLGASAEVANTIVFLSSEASSY 236 +PG E+DM + + QV++ K+ IPL++L +++A+ ++FL S + + Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGH 245 Query: 237 IVGQTLIVDGG 247 I L VDGG Sbjct: 246 ITMHNLCVDGG 256
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 33.6 bits (77), Expect = 0.001 Identities = 42/237 (17%), Positives = 79/237 (33%), Gaps = 19/237 (8%) Query: 139 FGFMA----IGFILGEM--GFSG---STMTWYIASAVGVLLGFYCFTLPNTPPKAKGQPF 189 FGFM+ G + G + G G ++ A+A+ L L K + +P Sbjct: 133 FGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPL 192 Query: 190 SLRDILCLDALSL-FKDRYFAILMFSIFILMIPKTAYSAYIPVF-IKALGFDNAA---SI 244 + L + A LM FI+ + +A +F +D S+ Sbjct: 193 RREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISL 252 Query: 245 MQIGIACEVLFMFVLSFFLMKFGFKITLLLGAVSWIIRSMFFSYAAVNTELYFIVIGLML 304 GI + + + G + L+LG I + A T + ++L Sbjct: 253 AAFGILHSLAQAMITGPVAARLGERRALMLG---MIADGTGYILLAFATRGWMAFPIMVL 309 Query: 305 QGLCWDFFFTAGDIYVDRKAKPEIRAQAQGLRFIVSNGFGLLFASTICGQIFNTTVT 361 A + R+ E + Q QG +++ + + I+ ++T Sbjct: 310 LA-SGGIGMPALQAMLSRQVDEERQGQLQGSLAALTS-LTSIVGPLLFTAIYAASIT 364
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 192 bits (488), Expect = 2e-57 Identities = 62/330 (18%), Positives = 127/330 (38%), Gaps = 24/330 (7%) Query: 61 RIYPLQYADVTTVAQQLTNYGISLLSDHG------------RIAIDKDSNSLSIIDTEKA 108 ++ L+YA + + + LT ++ S+ I +N+L + Sbjct: 270 KVIYLKYAKASDLVEVLTGISSTMQSEKQAAKPVAALDKNIIIKAHGQTNALIVTAAPDV 329 Query: 109 HTEISDWLKIKETPQQQVHITAHIISSSQDALNELGTQWGLLNMKSANLEGTSNNTTTPH 168 ++ + + + QV + A I LG QW N + +T Sbjct: 330 MNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLGIQWANKNAGMTQFTNSGLPISTAI 389 Query: 169 NIASAPLTAPSLAALALHQKTKNPLHYIAFNIARINSRLLELELSALEQEKQLAIIASPR 228 A+ ++++ + A + L+AL + I+A+P Sbjct: 390 AGANQYNKDGTVSSSLASALSS-----FNGIAAGFYQGNWAMLLTALSSSTKNDILATPS 444 Query: 229 LTAAHEKTASIKQGTEIPYVSR------DNDTIRVEFKEAVLGMEVTPIIQRSNKIRLLL 282 + A+ G E+P ++ DN VE K + ++V P I + + L + Sbjct: 445 IVTLDNMEATFNVGQEVPVLTGSQTTSGDNIFNTVERKTVGIKLKVKPQINEGDSVLLEI 504 Query: 283 KISQNTPGIALVQGGSE-HLSIDKQEIMTEVTIHDGETLMLGGIFQQKQQQHAAKIPFLS 341 + ++ A S+ + + + + V + GET+++GG+ + A K+P L Sbjct: 505 EQEVSSVADAASSTSSDLGATFNTRTVNNAVLVGSGETVVVGGLLDKSVSDTADKVPLLG 564 Query: 342 SLPLLGILFSHKRDQHSRHELVIFITPKLI 371 +P++G LF + S+ L++FI P +I Sbjct: 565 DIPVIGALFRSTSKKVSKRNLMLFIRPTVI 594
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 29.0 bits (65), Expect = 0.008 Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 18/91 (19%) Query: 32 FYDSDQEIERRTGADVGWVFDVEGEEGFRQ----------REEKIINELTEKQGIVLATG 81 FYD + +R + GW+ + G+R+ E + I +L E+ IV+A+G Sbjct: 136 FYDEETA--KRLAREKGWIVKEDSGRGWRRVVPSPDPKGHVEAETIKKLVERGVIVIASG 193 Query: 82 GGSVKSRETRNRLSARGVVVYLETNIEKQLA 112 GG V + +GV E I+K LA Sbjct: 194 GGGVPVILEDGEI--KGV----EAVIDKDLA 218
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 37.0 bits (85), Expect = 2e-05 Identities = 27/145 (18%), Positives = 53/145 (36%), Gaps = 20/145 (13%) Query: 25 VWPPIMAAIEKRQKEIADGLSS----AERAKKDLDLAKADAGEQLAKAKAE--------- 71 V PP A + + +A+ E+ ++D A E +AK+ Sbjct: 1025 VPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNE 1084 Query: 72 -AQAIIESANKQRTQMIEEA------KAEAEQERSKIVAQAQSELEAERKRAREELRKQV 124 AQ+ E+ Q T+ E A KA+ E E+++ V + S++ +++++ + Sbjct: 1085 VAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAE 1144 Query: 125 AMLAIAGAEKIIERSVDEAANSDIV 149 I E +D Sbjct: 1145 PARENDPTVNIKEPQSQTNTTADTE 1169
>TETREPRESSOR#Tetracycline repressor protein signature. Length = 218 Score = 131 bits (332), Expect = 1e-40 Identities = 67/212 (31%), Positives = 104/212 (49%), Gaps = 16/212 (7%) Query: 5 KIDRLNVLDTALSLLEKEGIEGLTMRKLADALHIKAASLYWHFDNKQTLIEGMADRIVSE 64 +++R +V+D AL LL + GI+GLT RKLA L I+ +LYWH NK+ L++ +A I++ Sbjct: 3 RLNRESVIDAALELLNETGIDGLTTRKLAQKLGIEQPTLYWHVKNKRALLDALAVEILAR 62 Query: 65 VAVDFHYS-----QDWKADLKRLATELREAFLQHRDGARVFAGTYVISENVLRINNTLIT 119 YS + W++ L+ A R A L++RDGA+V GT E T + Sbjct: 63 ---HHDYSLPAAGESWQSFLRNNAMSFRRALLRYRDGAKVHLGT-RPDEKQYDTVETQLR 118 Query: 120 LIMQSGASAELASNMSMTLLYFILGCCIEQQAITLIDSEILMQKRLAFEQIVRDKYPQTW 179 + ++G S + +F LG +EQQ T ++ ++R+ Sbjct: 119 FMTENGFSLRDGLYAISAVSHFTLGAVLEQQEHTAALTDRPAAPDENLPPLLREALQ--- 175 Query: 180 QVREILFADDFAMRFNFGLEQLVTGFEHQLKT 211 I+ +DD F GLE L+ GFE QL Sbjct: 176 ----IMDSDDGEQAFLHGLESLIRGFEVQLTA 203
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 108 bits (271), Expect = 3e-28 Identities = 69/353 (19%), Positives = 134/353 (37%), Gaps = 47/353 (13%) Query: 34 ATADWDRWWSDARYQTTDNAYIKADSTILKSRMTGFISQINKEDYQVVKRGEVIAEI-NK 92 A AD + S + + S ++ + ++ +Q V EV+ Sbjct: 132 AEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLI 191 Query: 93 KEQILNRQAALAEYQKAQLALDNLTEEIKEYQLNIEKLANRYQASVIDVTQAKRSPMLRK 152 KEQ Q + +L LD E I + N + V +++ Sbjct: 192 KEQFSTWQNQKYQ---KELNLDKKRAERLTVLARINRYENLSR-----VEKSRLDDF--S 241 Query: 153 DLINSGAITQQNYLDAQSDLQRLMKLQSAAKNEWDQAKQALVLLKSQ------------- 199 L++ AI + L+ ++ + K++ +Q + ++ K + Sbjct: 242 SLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEIL 301 Query: 200 EKIRLAQKDIAQ--TQYQQAETELSYATIKAPFDAQLNKIKVN-IGSLVTAGSEIVTLTP 256 +K+R +I + + E + I+AP ++ ++KV+ G +VT ++ + P Sbjct: 302 DKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVP 361 Query: 257 INDVYII-ANLKETQIKKVQPEQSVAIKVDAFP---TDVFSGKVRYIGAQSSGESALIPA 312 +D + A ++ I + Q+ IKV+AFP GKV+ I + Sbjct: 362 EDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAI-------E 414 Query: 313 DNASGNFTKVVQRIPVYITLNSDNRHLAKLRAGMSVQVKIDTDSLPIEEGERS 365 D G V+ I L++ N+++ L +GM+V +I T G RS Sbjct: 415 DQRLGLVFNVIISIEEN-CLSTGNKNI-PLSSGMAVTAEIKT-------GMRS 458
>FIMBRIALPAPF#Escherichia coli: P pili tip fibrillum papF protein signature. Length = 167 Score = 31.2 bits (70), Expect = 0.002 Identities = 36/113 (31%), Positives = 49/113 (43%), Gaps = 15/113 (13%) Query: 7 LAISLLALSSGTTLAANPIAKLKVTGRIKPPTCTINNEEQEATIIYNFDITPGLFPEKGD 66 L ISLL T++A ++ + G + P CTINN + I+ +F + PE D Sbjct: 6 LFISLLL----TSVAVLADVQINIRGNVYIPPCTINNGQN---IVVDFG---NINPEHVD 55 Query: 67 LKLAGQSKNIVISCD-SSTYLAFVATDNRLGTQSQESEA----FFGLGHYQFK 114 +KNI ISC S L T N +G A FG+ YQ K Sbjct: 56 NSRGEVTKNISISCPYKSGSLWIKVTGNTMGVGQNNVLATNITHFGIALYQGK 108
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 30.3 bits (68), Expect = 0.004 Identities = 9/32 (28%), Positives = 17/32 (53%) Query: 117 VTIDHHYRGKGIAQRLINTLKEHAKKQGYLGV 148 + + YR KG+ L++ E AK+ + G+ Sbjct: 95 IAVAKDYRKKGVGTALLHKAIEWAKENHFCGL 126
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 71.5 bits (175), Expect = 5e-17 Identities = 39/204 (19%), Positives = 76/204 (37%), Gaps = 17/204 (8%) Query: 64 STTMIEPRIKIESQQPPIALPRSENGEFIEAPKQPAKKRQQQPTPITPKVIKQVKKQPVV 123 S TM+ P + + P P E E +P + ++ + K + K +P Sbjct: 51 SVTMVAPA---DLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKP 107 Query: 124 DKTVPIKPRDLTNHNIVQSTSQPSAENLTQHTASSLAGSSRALSENGIGQGESENHYISL 183 K V RD+ E+ + A + S + S Sbjct: 108 VKKVEQPKRDV-----------KPVESRPASPFENTAPARPTSSTATAATSKPVTSVASG 156 Query: 184 LRREIERHKRYPAQARRMQDEGLVVVRFSLTNEGYISSVALEQTSGVASLDNAALAAVKR 243 R +YPA+A+ ++ EG V V+F +T +G + +V + + A++R Sbjct: 157 PRALSRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRR 216 Query: 244 VKPIGPKPNNLSDPLTISLKFQLN 267 + KP + + +++ F++N Sbjct: 217 WRYEPGKPGS---GIVVNILFKIN 237
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 725 bits (1874), Expect = 0.0 Identities = 385/551 (69%), Positives = 445/551 (80%), Gaps = 10/551 (1%) Query: 1 MDSQRNLLFIALLFVSFLIWQQWEGDKVSQ-NTTTTTQVSQQADMPSSDSLAVTGNSNEQ 59 MDSQRNLL IALLFVSF+IWQ WE DK Q TTQ + A ++D Q Sbjct: 1 MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAAGSAADQGVPASG---Q 57 Query: 60 AKLITVKTDVLDLRINTQGGTIDEADLLAYPAELNSKTPFRLLETTPQFLYQAQSGLIGP 119 KLI+VKTDVLDL INT+GG +++A L AYP ELNS PF+LLET+PQF+YQAQSGL G Sbjct: 58 GKLISVKTDVLDLTINTRGGDVEQALLPAYPKELNSTQPFQLLETSPQFIYQAQSGLTGR 117 Query: 120 DGPD---QKSRPVYSATQQEFILGENQDELRVPMTFVNEEGVKFVKTFILKKGQYDIGIE 176 DGPD RP+Y+ + ++L E Q+EL+VPMT+ + G F KTF+LK+G Y + + Sbjct: 118 DGPDNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYTDAAGNTFTKTFVLKRGDYAVNVN 177 Query: 177 YKVENPTDKTLTMNFYGQLKQSVKLPEHRDTGSSNFALHTYRGAAYSSDETNYKKYSFGD 236 Y V+N +K L ++ +GQLKQS+ LP H DTGSSNFALHT+RGAAYS+ + Y+KY F Sbjct: 178 YNVQNAGEKPLEISSFGQLKQSITLPPHLDTGSSNFALHTFRGAAYSTPDEKYEKYKFDT 237 Query: 237 IEDK-NLSITTNNGWIAMLQQYFATAWIPAKDSQNNNFYSITLDNKSIALIGYKSAPITV 295 I D NL+I++ GW+AMLQQYFATAWIP D NNFY+ L N IA IGYKS P+ V Sbjct: 238 IADNENLNISSKGGWVAMLQQYFATAWIPHNDG-TNNFYTANLGN-GIAAIGYKSQPVLV 295 Query: 296 APNSTQDITSTLWVGPEIQSEMSAIAPHLDLSVDYGWLWFISQPLFKLLKFLHSFIGNWG 355 P T + STLWVGPEIQ +M+A+APHLDL+VDYGWLWFISQPLFKLLK++HSF+GNWG Sbjct: 296 QPGQTGAMNSTLWVGPEIQDKMAAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWG 355 Query: 356 FSIIMITFIVRGIMYPLTKAQYTSMAKMRLLQPKLAALRERIGDDKQRMSQEMMALYKQE 415 FSII+ITFIVRGIMYPLTKAQYTSMAKMR+LQPK+ A+RER+GDDKQR+SQEMMALYK E Sbjct: 356 FSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRISQEMMALYKAE 415 Query: 416 KVNPLGGCLPLIIQMPIFLALYYMLMGSVELRHAPFILWIQDLSAQDPYYILPLLMGVTM 475 KVNPLGGC PL+IQMPIFLALYYMLMGSVELR APF LWI DLSAQDPYYILP+LMGVTM Sbjct: 416 KVNPLGGCFPLLIQMPIFLALYYMLMGSVELRQAPFALWIHDLSAQDPYYILPILMGVTM 475 Query: 476 FIIQKLSPTAVTDPMQQKIMTFMPVVFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGL 535 F IQK+SPT VTDPMQQKIMTFMPV+FTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGL Sbjct: 476 FFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGL 535 Query: 536 EKRGLHSRDKK 546 EKRGLHSR+KK Sbjct: 536 EKRGLHSREKK 546
>BACSURFANTGN#Yersinia/Haemophilus virulence surface antigen signature. Length = 322 Score = 29.7 bits (66), Expect = 0.018 Identities = 14/55 (25%), Positives = 21/55 (38%) Query: 318 ISDFPSIRDVVDEKAVSFADSGDAQSFAQQIKLLREEPQRTSEKINHARSLVENY 372 I S R ++D K S + SF + + R S ++ R V NY Sbjct: 55 IKHNQSGRSMLDRKLTSDGKANQRSSFTFSMIMYRMIHFVLSTRVPAVRESVANY 109
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 218 bits (557), Expect = 4e-76 Identities = 73/155 (47%), Positives = 105/155 (67%) Query: 4 KAIYPGTFDPITYGHIDILTRAAGMFDTVLLAIAASARKNPMFSLEERVALAKEVTQHLP 63 AIYPG+FDPIT+GH+DI+ R +FD V +A+ + K PMFS++ER+ + HLP Sbjct: 2 NAIYPGSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPMFSVQERLEQIAKAIAHLP 61 Query: 64 NVEVVGFCELMANFAKKQQATILIRGVRSVSDFEYEWQLANMNRHFAPDLDSVFLLPSQN 123 N +V F L N+A+++QA ++RG+R +SDFE E Q+AN N+ A DL++VFL S Sbjct: 62 NAQVDSFEGLTVNYARQRQAGAILRGLRVLSDFELELQMANTNKTLASDLETVFLTTSTE 121 Query: 124 LSFVSSSLIKDVARHDGDVSTFLPEVVATAMLQKL 158 SF+SSSL+K+VAR G+V F+P VA A+ + Sbjct: 122 YSFLSSSLVKEVARFGGNVEHFVPSHVAAALYDQF 156
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 90.6 bits (225), Expect = 6e-23 Identities = 79/355 (22%), Positives = 129/355 (36%), Gaps = 79/355 (22%) Query: 2 IIVTGGAGFIGSNIVKALNDEGYTDILVVDNLKD--------------GTKFVNLVDLNI 47 +VTG AGFIG ++ K L + G+ ++ +DNL D +++ Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGH-QVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 48 ADYMDKEDFIASIVAGDDFGDIDAVFHEGACSSTTEWDGKYMMDNNYQYSK-------EL 100 AD D AS G + VF + +Y ++N + Y+ + Sbjct: 62 ADREGMTDLFAS-------GHFERVFISPHRLAV-----RYSLENPHAYADSNLTGFLNI 109 Query: 101 LHYCLDRQIP-FLYASSAATYGG-RTDHFIEERKYEAPLNVYGYSKFLFDEYVRQI---- 154 L C +I LYASS++ YG R F + + P+++Y +K + Sbjct: 110 LEGCRHNKIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLY 169 Query: 155 -LPEAQSMVCGFRYFNVYGPREGHKGSMASVAFHLNTQVNDGQNPKLFEGSETFQRDFIY 213 LP G R+F VYGP + MA F + +G++ ++ +RDF Y Sbjct: 170 GLP-----ATGLRFFTVYGPWG--RPDMA--LFKFTKAMLEGKSIDVY-NYGKMKRDFTY 219 Query: 214 VGDVAAVNL------------WFWRNNVSG-------IYNCGTGRAESFQAVADAVIAYH 254 + D+A + W +YN G A+ Sbjct: 220 IDDIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQAL---- 275 Query: 255 NDKDLSVE-HIEFPEKLKGRYQAFTQADLTNLRKA-GYSAPFKTVAEGVALYMQW 307 + L +E G T AD L + G+ P TV +GV ++ W Sbjct: 276 -EDALGIEAKKNMLPLQPGDVL-ETSADTKALYEVIGF-TPETTVKDGVKNFVNW 327
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 45.6 bits (108), Expect = 3e-07 Identities = 29/187 (15%), Positives = 57/187 (30%), Gaps = 14/187 (7%) Query: 110 ANIARLQKQYNEQQALLAR---QLDAAYRQGKHQGIELLFRGEEGQREERILAYYSYINE 166 A+ + Q + + R + + + EE +L S I E Sbjct: 134 ADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKE 193 Query: 167 ARKQSMEQLAQ---TSKELQAEKDAQQAKQNEQKQVLTKQQQE----KQKLDNALAARQK 219 Q Q + +AE+ A+ N + + ++ L A+ Sbjct: 194 QFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHA 253 Query: 220 TLTQLESTLKEDQRNLATMRANEIRLRNKIAQAEREAKARAEREAREAARIAAKQREAQQ 279 L Q E+ E L ++ ++ ++I A+ E + + E I K R+ Sbjct: 254 VLEQ-ENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNE---ILDKLRQTTD 309 Query: 280 RGSTYKP 286 Sbjct: 310 NIGLLTL 316 Score = 31.0 bits (70), Expect = 0.010 Identities = 13/94 (13%), Positives = 37/94 (39%), Gaps = 11/94 (11%) Query: 46 RSQLKDLQTTIAEK---EKRVQEQQKQRTALLGQLKSQETQIANASRSVHETQNRLQTL- 101 +S+L D + + ++ + V EQ+ + + +L+ ++Q+ + + Q + Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVT 293 Query: 102 -------AKEIKTITANIARLQKQYNEQQALLAR 128 +++ T NI L + + + Sbjct: 294 QLFKNEILDKLRQTTDNIGLLTLELAKNEERQQA 327
>SECBCHAPRONE#Bacterial protein-transport SecB chaperone protein signature. Length = 170 Score = 216 bits (551), Expect = 3e-75 Identities = 83/149 (55%), Positives = 114/149 (76%), Gaps = 2/149 (1%) Query: 3 EQQNQEMTFQIQRIYTKDISFEAPNAPQVFQKEWQPEVKLDLDTSSNTLAENVYEVILRV 62 Q Q+ QIQRIY KD+SFEAPN P +FQ++W+P++ DL T + + +++YEV L + Sbjct: 12 TQATQQPVLQIQRIYVKDVSFEAPNLPHIFQQDWEPKLSFDLSTEAKQVGDDLYEVCLNI 71 Query: 63 TVTATMEEE--TAFLCEVQQAGIFTVEGIEGTQLAHCLGAYCPNVLFPYARECITNLVGR 120 +V TME AF+CEV+QAG+FT+ G+E Q+AHCL + CPN+LFPYARE +++LV R Sbjct: 72 SVETTMESSGDVAFICEVKQAGVFTISGLEEMQMAHCLTSQCPNMLFPYARELVSSLVNR 131 Query: 121 GTFPQLNLAPVNFDALFMNYLQQQQQQDA 149 GTFP LNL+PVNFDALFM+YLQ+Q+Q + Sbjct: 132 GTFPALNLSPVNFDALFMDYLQRQEQAEQ 160
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 28.6 bits (64), Expect = 0.031 Identities = 20/87 (22%), Positives = 28/87 (32%), Gaps = 13/87 (14%) Query: 5 MTVI---GAGSYGTALAITLARNGHDVVLWGHD---PKHVAALEQARCNQAFLPDVSFPD 58 M + AG G ++ L GH VV G D + +L+QAR P F Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVV--GIDNLNDYYDVSLKQARLELLAQPGFQF-- 56 Query: 59 SLYMEASLQKAIEASRNILVVIPSHVF 85 + L + VF Sbjct: 57 ---HKIDLADREGMTDLFASGHFERVF 80
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 559 bits (1442), Expect = 0.0 Identities = 225/335 (67%), Positives = 268/335 (80%), Gaps = 1/335 (0%) Query: 1 MKYLVTGAAGFIGFHLIKKLIQQGETVVGIDNLNDYYDVALKEARLNLLNQLDNFSFSFI 60 MKYLVTGAAGFIGFH+ K+L++ G VVGIDNLNDYYDV+LK+ARL LL Q F F I Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQ-PGFQFHKI 59 Query: 61 DLADREKIAQLFEIEKFDRVIHLAAQAGVRYSLINPFSYADSNLTGFLTILEGCRHNNVK 120 DLADRE + LF F+RV + VRYSL NP +YADSNLTGFL ILEGCRHN ++ Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ 119 Query: 121 HLVYASSSSVYGLNDELPFSPHDQANHPVSLYAATKKANELMAHSYSHLYGIPTTGLRFF 180 HL+YASSSSVYGLN ++PFS D +HPVSLYAATKKANELMAH+YSHLYG+P TGLRFF Sbjct: 120 HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFF 179 Query: 181 TVYGPWGRPDMALFKFTKAIINNQPIDIYNHGEMKRDFTYVEDIVEGVTRIADVIPTAQQ 240 TVYGPWGRPDMALFKFTKA++ + ID+YN+G+MKRDFTY++DI E + R+ DVIP A Sbjct: 180 TVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHADT 239 Query: 241 DWKVSTGTPADSSAPYKVYNIGNGSPVNLMDYISALEIHLGKKADKNMLPMQPGDVYTTW 300 W V TGTPA S APY+VYNIGN SPV LMDYI ALE LG +A KNMLP+QPGDV T Sbjct: 240 QWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQPGDVLETS 299 Query: 301 ADTEDLFKATGYKPQTSVDEGVKQFVDWYKNYYQV 335 ADT+ L++ G+ P+T+V +GVK FV+WY+++Y+V Sbjct: 300 ADTKALYEVIGFTPETTVKDGVKNFVNWYRDFYKV 334
>adhesinb#Adhesin B signature. Length = 310 Score = 29.8 bits (67), Expect = 0.009 Identities = 22/152 (14%), Positives = 48/152 (31%), Gaps = 30/152 (19%) Query: 82 MLKNVDVKYVIIGHSERRTYHKESDEFIAQKFGVLKELGLTPVLCIGETEAENEAGKTQE 141 +N+ + + + TY K ++ + L L + EA + Sbjct: 151 YAQNIAKRLSEKDPANKETYEKNLKAYVEK----LSAL-------------DKEAKEKFN 193 Query: 142 VCARQIDAILNAHGAQAF--KDAVIAYEPIWAIGTGKSATPAQAQAVHKFIRDH------ 193 + I+ + G + K + IW I T + TP Q + + + +R Sbjct: 194 NIPGEKKMIVTSEGCFKYFSKAYNVPSAYIWEINTEEEGTPDQIKTLVEKLRKTKVPSLF 253 Query: 194 -----IAKQDAAIAEQVIIQYGGSVNDKNAAE 220 + +++ I + + AE Sbjct: 254 VESSVDDRPMKTVSKDTNIPIYAKIFTDSVAE 285
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 67.6 bits (165), Expect = 2e-14 Identities = 53/229 (23%), Positives = 102/229 (44%), Gaps = 17/229 (7%) Query: 4 LEHANLLLLIIALVAVGQMTQTIYVPVIADMAVYFGEPTGAVQQVMGAYLFSYGFSQLIY 63 L H +L+ + L + + + + D+A F +P + V A++ ++ +Y Sbjct: 10 LRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVY 69 Query: 64 GPISDRVGRRPVILVGMSIFCLATIVAIFSQNLTTLVIASTL-QGMGTG-----VAGVMT 117 G +SD++G + ++L G+ I C +++ + +L+I + QG G V V+ Sbjct: 70 GKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVA 129 Query: 118 RTQPRDLYTGTALRYANSLLNMGVLVSPLLAPMIGGVVAHFFGWHACYIFLLLLGGSVLF 177 R P++ G A S++ MG V P IGG++AH+ W + ++ +V F Sbjct: 130 RYIPKE-NRGKAFGLIGSIVAMGEGVGPA----IGGMIAHYIHWSYLLLIPMITIITVPF 184 Query: 178 SMYHWMPETRPVQ------AERRSMLSSFYLLLSNSTFSAFLIMLICAL 220 M E R S+ F++L + S +FLI+ + + Sbjct: 185 LMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSF 233
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 32.1 bits (73), Expect = 0.005 Identities = 16/83 (19%), Positives = 32/83 (38%), Gaps = 15/83 (18%) Query: 2 SEMTPREIASELDRFIIGQDKAKRAVAIALRNRWRRMQLDEALRHEVTPKNILMIGPTGV 61 + E S+ ++G+ A + + L ++ T +++ G +G Sbjct: 124 RRPSKLEDDSQDGMPLVGRSAAMQEI---------YRVLARLMQ---TDLTLMITGESGT 171 Query: 62 GKTEIAR---RLAKLANAPFIKV 81 GK +AR K N PF+ + Sbjct: 172 GKELVARALHDYGKRRNGPFVAI 194
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.0 bits (70), Expect = 0.013 Identities = 11/51 (21%), Positives = 25/51 (49%) Query: 515 AVTAPISGILHSWLLSDGDKVNQGDVIAIMEAMKMEVQVVATCHGVLQQKA 565 + + I+ ++ +G+ V +GDV+ + A+ E + T +LQ + Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARL 148
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 85.9 bits (212), Expect = 2e-19 Identities = 42/265 (15%), Positives = 86/265 (32%), Gaps = 25/265 (9%) Query: 18 KEENTAQEKEQQRLEAERAEQARLAEEEAQRQAQLEAEQVRLAEEEAQRQAQLEAEQARQ 77 K T +A+ + + EA A + AE ++Q Sbjct: 987 KRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQ 1046 Query: 78 EAQRAEAERLAAERAEQARLAEEEAQRQAQLEAEQARQEAQRAEAERLAAERAEQARLAE 137 E++ E A E Q + A++A+ +A E A+ + Sbjct: 1047 ESKTVEKNEQDA----------TETTAQNREVAKEAKSN---VKANTQTNEVAQSGSETK 1093 Query: 138 EEAQRQAQQEAEQARQEAQRAEAERLAAERAEQARLAEEEAQRQAQLEAEQARQEAQRAE 197 E + ++ A ++E + E E+ +E + +Q+ +Q + E + + Sbjct: 1094 ETQTTETKETATVEKEEKAKVETEK-----------TQEVPKVTSQVSPKQEQSETVQPQ 1142 Query: 198 AEKLAAERAEQARLAEEEAQRQAQLEAEQARQEAQRAEAERLAAERAEQTRLAEEEAQRQ 257 AE A E + E ++Q + EQ +E + + T + E Sbjct: 1143 AEP-ARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPEN 1201 Query: 258 AQLEAEQARQEAEAEEKARIAQAQA 282 Q +E+ K + ++ Sbjct: 1202 TTPATTQPTVNSESSNKPKNRHRRS 1226 Score = 72.8 bits (178), Expect = 2e-15 Identities = 33/196 (16%), Positives = 72/196 (36%), Gaps = 11/196 (5%) Query: 124 RLAAERAEQARLAEEEAQRQAQQEAEQARQEAQRAEAERLAAERAEQARLAEEEAQRQAQ 183 L E+ + + E + A A + Sbjct: 979 DLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTE 1038 Query: 184 LEAEQARQEAQRAE-AEKLAAERAEQARLAEEEAQRQAQLE---AEQARQEAQRAEAERL 239 AE ++QE++ E E+ A E Q R +EA+ + E A+ ++ E + Sbjct: 1039 TVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTT 1098 Query: 240 AA------ERAEQTRLAEEEAQRQAQLEAEQARQEAEAEEKARIAQAQAEAEDIVALRE- 292 E+ E+ ++ E+ Q ++ ++ + ++ ++E A+ E + V ++E Sbjct: 1099 ETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEP 1158 Query: 293 EVLVDKPVEQERPKKE 308 + + + E+P KE Sbjct: 1159 QSQTNTTADTEQPAKE 1174 Score = 68.9 bits (168), Expect = 3e-14 Identities = 42/268 (15%), Positives = 86/268 (32%), Gaps = 24/268 (8%) Query: 23 AQEKEQQRLEAERAEQARLAEEEAQRQAQLEAEQVRLAEEEAQRQAQLE---AEQARQEA 79 A E AE ++Q E+ ++ A Q R +EA+ + E A+ + Sbjct: 1031 ATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGS 1090 Query: 80 QRAEAERLAAERAEQARLAEEE------------AQRQAQLEAEQARQEAQRAEAERLAA 127 + E + + E A + +EE + +Q+ +Q + E + +AE A Sbjct: 1091 ETKETQTTETK--ETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEP-AR 1147 Query: 128 ERAEQARLAEEEAQRQAQQEAEQARQEAQRAEAERLAAERAEQARLAEEEAQRQAQLEAE 187 E + E ++Q + EQ +E + + + E Sbjct: 1148 ENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATT 1207 Query: 188 QARQEAQRAEAEKLAAERAEQARLAEEEA------QRQAQLEAEQARQEAQRAEAERLAA 241 Q ++ + K R+ ++ E R + ++ A Sbjct: 1208 QPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAK 1267 Query: 242 ERAEQTRLAEEEAQRQAQLEAEQARQEA 269 + + + +Q +QLE Q Sbjct: 1268 AQFVALNVGKAVSQHISQLEMNNEGQYN 1295 Score = 68.6 bits (167), Expect = 4e-14 Identities = 35/212 (16%), Positives = 73/212 (34%), Gaps = 15/212 (7%) Query: 86 RLAAERAEQARLAEEEAQRQAQLEAEQARQEAQRAEAERLAAERAEQARLAEEEAQRQAQ 145 L E+ + + E + A A + Sbjct: 979 DLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTE 1038 Query: 146 QEAEQARQEAQRAE-AERLAAERAEQARLAEEEAQRQAQLE---AEQARQEAQRAEAEKL 201 AE ++QE++ E E+ A E Q R +EA+ + E A+ ++ E + Sbjct: 1039 TVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTT 1098 Query: 202 AAERA---EQARLAEEEAQRQ-------AQLEAEQARQEAQRAEAERLAAERAEQTRLAE 251 + E+ A+ E ++ +Q+ +Q + E + +AE A E + E Sbjct: 1099 ETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEP-ARENDPTVNIKE 1157 Query: 252 EEAQRQAQLEAEQARQEAEAEEKARIAQAQAE 283 ++Q + EQ +E + + + ++ Sbjct: 1158 PQSQTNTTADTEQPAKETSSNVEQPVTESTTV 1189 Score = 57.4 bits (138), Expect = 2e-10 Identities = 33/220 (15%), Positives = 70/220 (31%), Gaps = 23/220 (10%) Query: 18 KEENTAQEKEQQRLEAERAEQARLAEEEAQRQAQLEAEQVRLAEEEAQRQAQLEAEQARQ 77 KE T + KE E + +A++E E+ +E + +Q+ +Q + Sbjct: 1093 KETQTTETKETA-------------TVEKEEKAKVETEKT---QEVPKVTSQVSPKQEQS 1136 Query: 78 EAQRAEAERLAAERAEQARLAEEEAQRQAQLEAEQARQEAQRAEAERLAAERAEQARLAE 137 E + +AE A E + E ++Q + EQ +E + + + Sbjct: 1137 ETVQPQAEP-ARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSV 1195 Query: 138 EEAQRQAQQEAEQARQEAQRAEAERLAAERAEQARLAEEEA------QRQAQLEAEQARQ 191 E Q ++ + + R+ ++ E R + Sbjct: 1196 VENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTST 1255 Query: 192 EAQRAEAEKLAAERAEQARLAEEEAQRQAQLEAEQARQEA 231 ++ A + + + +Q +QLE Q Sbjct: 1256 NTNAVLSDARAKAQFVALNVGKAVSQHISQLEMNNEGQYN 1295
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 37.8 bits (87), Expect = 7e-05 Identities = 43/187 (22%), Positives = 72/187 (38%), Gaps = 12/187 (6%) Query: 132 DGKMISLPFNSSTPVLYYNKALFKQAGIEQPPKTWKEMGAVSQKLLDAGVKCGFTTTWQS 191 +GK+I+ P L YNK L + PPKTW+E+ A+ ++L G + Sbjct: 126 NGKLIAYPIAVEALSLIYNKDL-----LPNPPKTWEEIPALDKELKAKGKSALMFNLQEP 180 Query: 192 WTQIENFGARNNLPIATKNNGFDGTDTSFLFNQAPFVTHIQRMADWSKSGIFKYGGRQSD 251 + A +N +D D + A + + D K+ S Sbjct: 181 YFTWPLIAADGGYAFKYENGKYDIKDVG--VDNAGAKAGLTFLVDLIKNKHMNADTDYSI 238 Query: 252 AMPLFYTQECAMVMESSAGFAGIKENMKGIDIGVSQLPYDDTLVDKPANSIIGGASLWVM 311 A F E AM + ++ I + ++ GV+ LP T +P+ +G S + Sbjct: 239 AEAAFNKGETAMTINGPWAWSNIDTSK--VNYGVTVLP---TFKGQPSKPFVGVLSAGIN 293 Query: 312 AGRPDAE 318 A P+ E Sbjct: 294 AASPNKE 300
>DNABINDNGFIS#DNA-binding protein FIS signature. Length = 98 Score = 155 bits (393), Expect = 3e-53 Identities = 96/98 (97%), Positives = 97/98 (98%) Query: 1 MFEQRVNSDVLTVATVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQ 60 MFEQRVNSDVLTV+TVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQ Sbjct: 1 MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQ 60 Query: 61 PLLDMVMQYTRGNQTRAAQMMGINRGTLRKKLKKYGMN 98 PLLDMVMQYTRGNQTRAA MMGINRGTLRKKLKKYGMN Sbjct: 61 PLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN 98
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 25.1 bits (55), Expect = 0.035 Identities = 12/69 (17%), Positives = 25/69 (36%), Gaps = 6/69 (8%) Query: 10 KEALLALVLTFIYLLGWLLTAYLPDNSVG-----LTGLPVWFELSCLFLPVLFFLLCYLM 64 K LL++++ I + LP + L + + C V+ + Y Sbjct: 146 KVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLLGQILRQLMVICTVGFVVISIADYAF 205 Query: 65 VRYFF-KDM 72 Y + K++ Sbjct: 206 EYYQYIKEL 214
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 32.1 bits (73), Expect = 0.003 Identities = 14/52 (26%), Positives = 22/52 (42%) Query: 150 ILVTGASGGVGSTAISLLTALGYQVTALSGRASNHDYLRKLGAEHIITREAF 201 LVTGA+G +G L G+QV + +D K ++ + F Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGF 54
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 55.0 bits (132), Expect = 1e-10 Identities = 35/181 (19%), Positives = 63/181 (34%), Gaps = 35/181 (19%) Query: 55 PAVVNVYSSTMGSFSQEGRELTSLGAGVIMDPRGYILTNQHVINNADQIIVAL------Q 108 V + T + +GV++ +LTN+HV++ AL Sbjct: 88 APVTYIQVEAPTG--------TFIASGVVVGK-DTLLTNKHVVDATHGDPHALKAFPSAI 138 Query: 109 NGDLY------EGLLIGSDPLTDLAVLKVDA--------EKLPTIPINSKRISHVGDVVL 154 N D Y + DLA++K E + +++ + V + Sbjct: 139 NQDNYPNGGFTAEQITKYSGEGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNIT 198 Query: 155 AIGNPFNIGQTITQGIISATGRVGLSPTRYQNFLQTDASINEGNSGGALINTEGELVGIN 214 G P + T + G++ +Q D S GNSG + N + E++GI+ Sbjct: 199 VTGYPGD-KPVATMW--ESKGKITYLKG---EAMQYDLSTTGGNSGSPVFNEKNEVIGIH 252 Query: 215 T 215 Sbjct: 253 W 253
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 76.6 bits (188), Expect = 2e-17 Identities = 33/179 (18%), Positives = 62/179 (34%), Gaps = 38/179 (21%) Query: 95 GLGSGVIIDAEKGYVLTNNHVVDGADKIQLQI------------NDGREFDAKLIGSDPQ 142 + SGV++ K +LTN HVVD + +G ++ + Sbjct: 102 FIASGVVVG--KDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGE 159 Query: 143 TDIALLQIEK-------PNNLTAIKMTDSDKLRVGDFAVAVGNPFGLGQTATSGIISALG 195 D+A+++ + M+++ + +V G P ++ + Sbjct: 160 GDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKP-------VATMW 212 Query: 196 RSGLNLEGLEN-FIQTDASINRGNSGGALVNLNGELIGINTAILAPGGGNIGIGFAIPS 253 S + L+ +Q D S GNSG + N E+IGI+ G+ Sbjct: 213 ESKGKITYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHWG---------GVPNEFNG 262
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 30.0 bits (67), Expect = 0.003 Identities = 13/32 (40%), Positives = 21/32 (65%) Query: 8 NSAVLLNFTLKLADGSVAESTQAHGKPALFRL 39 + V + +T L DG+V +ST+ GKPA F++ Sbjct: 144 SDTVTVEYTGTLIDGTVFDSTEKAGKPATFQV 175
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.0 bits (70), Expect = 0.026 Identities = 26/145 (17%), Positives = 50/145 (34%), Gaps = 24/145 (16%) Query: 34 CKALREEGYRVVLVNS-----------NPATIMTDPEMADATYIEPIHWQVVRKIIEKER 82 +AL GY V + ++ + ++TD M D + + I+K R Sbjct: 20 NQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD------LLPRIKKAR 73 Query: 83 PDAILPTMGGQTALNCALELERQGVLAEFGVTM-IGATADAIDKAEDRQRFDKAMKKIGL 141 PD + M Q A++ +G + I +A + + K+ Sbjct: 74 PDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK--RRPSKLED 131 Query: 142 DTARS----GIAHTMDEAFAVAEQV 162 D+ G + M E + V ++ Sbjct: 132 DSQDGMPLVGRSAAMQEIYRVLARL 156
>HOKGEFTOXIC#Hok/Gef cell toxic protein family signature. Length = 52 Score = 35.2 bits (81), Expect = 4e-07 Identities = 10/40 (25%), Positives = 22/40 (55%) Query: 6 LFGITVVCVTVLMFALIVGERLCSLNISNGNMVVQAILMC 45 ++ + +VC+T+L+F + + LC + +G V A + Sbjct: 9 VWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAY 48
>INTIMIN#Intimin signature. Length = 939 Score = 397 bits (1022), Expect = e-120 Identities = 204/724 (28%), Positives = 319/724 (44%), Gaps = 46/724 (6%) Query: 154 AISQISSKSNQKIEQWLNQFGHARVSLSADKNLTLKNSSAELLIPLYEQKEKLIFAQTNY 213 A+ ++++ +++ WL +G A V+L + N SS + L+P Y+ ++ L F Q Sbjct: 191 ALGIAGNQASSQLQAWLQHYGTAEVNLQSGNNFD--GSSLDFLLPFYDSEKMLAFGQVGA 248 Query: 214 HRKDLRSQFNYGIGYRYFTEKFMVGINGFYDHDLTHHHNRLGIGAEIWRDYFKLSSNHYH 273 D R N G G R+F + M+G N F D D + + RLGIG E WRDYFK S N Y Sbjct: 249 RYIDSRFTANLGAGQRFFLPENMLGYNVFIDQDFSGDNTRLGIGGEYWRDYFKSSVNGYF 308 Query: 274 RLSSWRASNNILDYSERPANGWDIRTEGYFPAYPQLGTKLIFEQYYGKEVGLFGKDKRDK 333 R+S W S N DY ERPANG+DIR GY P+YP LG KL++EQYYG V LF DK Sbjct: 309 RMSGWHESYNKKDYDERPANGFDIRFNGYLPSYPALGAKLMYEQYYGDNVALFNSDKLQS 368 Query: 334 NPHTYTLGINYTPIPLVTLNAERRIGLHDRADNNLNINLSYRIGESLASQLNPDNVKAIR 393 NP T+G+NYTPIPLVT+ + R G + D ++ Y+ + + Q+ P V +R Sbjct: 369 NPGAATVGVNYTPIPLVTMGIDYRHGTGNENDLLYSMQFRYQFDKPWSQQIEPQYVNELR 428 Query: 394 TLAGSRYDFVNRNNDMILEYKKETLVFLSMVDSINGYAKEERDLQVQVKTKYPLANIEWS 453 TL+GSRYD V RNN++ILEYKK+ ++ L++ ING + + +Q+ VK+KY L I W Sbjct: 429 TLSGSRYDLVQRNNNIILEYKKQDILSLNIPHDINGTERSTQKIQLIVKSKYGLDRIVWD 488 Query: 454 ASKLNAQGGQIKHHG---GTHYTVILPQYQIGAIEKNSYIISAVAIDTHGNRSAPVQTTV 510 S L +QGGQI+H G Y ILP Y G N Y ++A A D +GN S V T+ Sbjct: 489 DSALRSQGGQIQHSGSQSAQDYQAILPAYVQGGS--NVYKVTARAYDRNGNSSNNVLLTI 546 Query: 511 IVDKS---LINTRNSLFSPKQSQLFANGEATQKLILSIVDNDNLPVDIDSKEITLQQQSD 567 V + + + F+ ++ A+G ++ N ++ + + Sbjct: 547 TVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKNGVAQANVPVSFNIVSGTAV 606 Query: 568 TEKGNSRISTFSRLAAGKYQLTVTAGSIPEKLTLTPVFRDNTFNSATVTLIADNQTAHIA 627 ++ + +GK +T+ + + + + +A + D A I Sbjct: 607 LSANSANTN-----GSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQTKASIT 661 Query: 628 KGNLTVTKDNEPADGKSQNKIKVRVTDSNHNPLAHYPVNFTASNGANVISSRKTDEQGEI 687 + K A+G+ V+V P+++ V FT + G S+ KTD G Sbjct: 662 --EIKADKTTAVANGQDAITYTVKV-MKGDKPVSNQEVTFTTTLGKLSNSTEKTDTNGYA 718 Query: 688 IASVTNTQVGSSQIGVQVKGITYSTEVHFSVDNDSAYIPQQNFTITPPLSLADGK----- 742 ++T+T G S + +V + + L++ DG Sbjct: 719 KVTLTSTTPGKSLVSARVSDVAVD-------------VKAPEVEFFTTLTIDDGNIEIVG 765 Query: 743 --TEKTISLQVVDKQNNPIPATHVTLSADNQAQLKQTILTTDEQGKATTTMISKVAGTVT 800 + + + + A+ ++ G+ T K GT T Sbjct: 766 TGVKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPAIASVDASSGQVTL----KEKGTTT 821 Query: 801 VRAKINDKMTHATTQFIANQAKGVIVSITPSSTTHVADGQTPVFLTALVQDQFGKPLPHA 860 + +D T + +IV T+ D L + Sbjct: 822 ISVISSDNQ---TATYTIATPNSLIVPNMSKRVTY-NDAVNTCKNFGGKLPSSQNELENV 877 Query: 861 QISW 864 +W Sbjct: 878 FKAW 881 Score = 61.2 bits (148), Expect = 4e-11 Identities = 48/222 (21%), Positives = 94/222 (42%), Gaps = 9/222 (4%) Query: 915 ITFIANGQ---QALISELLVNKNQIVADKQDPAELTAIVTDKLGNQLPDTIVNWQGSAGT 971 IT ++NGQ Q +++ +K AD + TA V Q + S Sbjct: 546 ITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKNGVAQANVPVSFNIVSGTA 605 Query: 972 QFAQQQTKTDAQGIAKNTLTTSQSGITTITARLNNGQHAQTNLVAVADLKSATLTLTTLN 1031 + T+ G A TL + + G ++A+ A N AV + ++T + Sbjct: 606 VLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSA-LNANAVIFVDQTKASITEIK 664 Query: 1032 -NKQSAIADNQDSITVVANLTDAYHNPLKNIPVYWQSSINHIDETTTQTDEKGRTQVVIS 1090 +K +A+A+ QD+IT + P+ N V + +++ + +T +TD G +V ++ Sbjct: 665 ADKTTAVANGQDAITYTVKVMKG-DKPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLT 723 Query: 1091 GTKAQPTTITAYLSNK--EKKSIQVTFVAGAPVQQNSYLTIE 1130 T + ++A +S+ + K+ +V F + + I Sbjct: 724 STTPGKSLVSARVSDVAVDVKAPEVEFFTT-LTIDDGNIEIV 764 Score = 60.1 bits (145), Expect = 9e-11 Identities = 70/356 (19%), Positives = 122/356 (34%), Gaps = 49/356 (13%) Query: 729 NFTITPPLSLADGKTEKTISLQVVDKQNNPIPATHVTLSADNQAQLKQTILTTDEQGKAT 788 +FT + ADG T + V A L T+ GKAT Sbjct: 562 DFTADKTSAKADGTEAITYTATVKKNGVAQANVPVSFNIVSGTAVLSANSANTNGSGKAT 621 Query: 789 TTMISKVAGTVTVRAKINDKMTHATTQF--IANQAKGVIVSITPSSTTHVADGQTPVFLT 846 T+ S G V V AK + + +Q K I I TT VA+GQ + T Sbjct: 622 VTLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQTKASITEIKADKTTAVANGQDAITYT 681 Query: 847 ALVQDQFGKPLPHAQISWETEHDKSIVNIEHTTMTNEQ-GITTNKLTSTQALSVRVTARI 905 V + KP+ + ++++ ++ + ++T + G LTST V+AR+ Sbjct: 682 VKV-MKGDKPVSNQEVTF----TTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARV 736 Query: 906 NNNAFT--AEPITFIANGQQALISELLVNKNQIVADKQDPAELTAIVTDKLGNQLPDTIV 963 ++ A A + F + + +G + + Sbjct: 737 SDVAVDVKAPEVEFFT-----------------------TLTIDDGNIEIVGTGVKGKLP 773 Query: 964 NWQGSAGTQFAQQQTKTDAQGIAKNTLTTSQSGITTITARLN----NGQHAQTNLVAVAD 1019 Q+ Q K G K T ++ I ++ A + T V +D Sbjct: 774 T----VWLQYGQVNLKASG-GNGKYTWRSANPAIASVDASSGQVTLKEKGTTTISVISSD 828 Query: 1020 LKSATLTLTTLN-------NKQSAIADNQDSITVVANLTDAYHNPLKNIPVYWQSS 1068 ++AT T+ T N +K+ D ++ + N L+N+ W ++ Sbjct: 829 NQTATYTIATPNSLIVPNMSKRVTYNDAVNTCKNFGGKLPSSQNELENVFKAWGAA 884 Score = 60.1 bits (145), Expect = 1e-10 Identities = 62/335 (18%), Positives = 124/335 (37%), Gaps = 31/335 (9%) Query: 1369 TNLQTTITPFKEKQKGIYQAQVSAL-KTGKTSLSAHVAPLAIKQSVSLTVLPNNT---TA 1424 + Q + + + +Y+ A + G +S + +++TVL N Sbjct: 508 QDYQAILPAYVQGGSNVYKVTARAYDRNGNSSNNV---------LLTITVLSNGQVVDQV 558 Query: 1425 KVKNFTI--SNIQPHAGESITYKAYLVDNHDNPVGMGVPVAWSTNEGSQLETPLTF-TDD 1481 V +FT ++ + E+ITY A + N VPV+++ G+ + + + T+ Sbjct: 559 GVTDFTADKTSAKADGTEAITYTATVKKNGVAQAN--VPVSFNIVSGTAVLSANSANTNG 616 Query: 1482 NGVAIVGLSRRSVGVAKVSAILETGTYIADDVHFLTGHIDETMSELSLNPSQIIANGKDK 1541 +G A V L G VSA T A + + + S + + A + Sbjct: 617 SGKATVTLKSDKPGQVVVSAKTAEMTS-ALNANAVIFVDQTKASITEIKADKTTAVANGQ 675 Query: 1542 ALLTFVIK-DKNGNIIPNQQVSGFSKNPTIKFSQAQQISPGRYEIEITGTQSGTAQIGVM 1600 +T+ +K K + NQ+V+ + + S + + G ++ +T T G + + Sbjct: 676 DAITYTVKVMKGDKPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSAR 735 Query: 1601 VNGTHFK-KQKILQLNADVTTWKIRAVEVDRTTITAG--DKGVNYQATVVDANNNVLPNV 1657 V+ K ++ +T +E+ T + + Y + A+ N Sbjct: 736 VSDVAVDVKAPEVEFFTTLTIDDGN-IEIVGTGVKGKLPTVWLQYGQVNLKASGG---NG 791 Query: 1658 IVSWKL----LGSADDYHYSTYTNDKGIATNRVTS 1688 +W+ + S D +KG T V S Sbjct: 792 KYTWRSANPAIASVDASSGQVTLKEKGTTTISVIS 826 Score = 48.5 bits (115), Expect = 3e-07 Identities = 62/287 (21%), Positives = 102/287 (35%), Gaps = 33/287 (11%) Query: 1091 GTKAQPTTITAY-----LSNKEKKSIQVTFVAGAPVQQNSY--LTIEPQSIIADGNA--- 1140 G+ T AY SN +I V G V Q T + S ADG Sbjct: 521 GSNVYKVTARAYDRNGNSSNNVLLTITV-LSNGQVVDQVGVTDFTADKTSAKADGTEAIT 579 Query: 1141 --FAVGKIDLRDKFDNPVIGRSNDIALIGDNSTIQFSKITETANGNYQAHIRGTKAGLSQ 1198 V K + + + PV + T S + NG+ +A + Q Sbjct: 580 YTATVKKNGV-AQANVPVSFNIV-------SGTAVLSANSANTNGSGKATVTLKSDKPGQ 631 Query: 1199 ITATIDSITVTQSLG----FLTDNKTVKIHSVKVMAPYTVTANGKDKVIIQAQITDKHNN 1254 + + + +T +L D I +K T ANG+D I + + Sbjct: 632 VVVSAKTAEMTSALNANAVIFVDQTKASITEIKA-DKTTAVANGQD--AITYTVKVMKGD 688 Query: 1255 PVSKGVTVGWISDLGKLAAPLSMTNKQGIAEITLSSTQAGKAKVTAVLNNQQSVNADHIV 1314 V + + LGKL+ T+ G A++TL+ST GK+ V+A +++ V Sbjct: 689 KPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEV 748 Query: 1315 TFTEGDISASLSTVAIFPDTIVAGANKATVTITLKDKEGNLLPNLAN 1361 F +L+ + + G T+ L+ + NL + N Sbjct: 749 EFF-----TTLTIDDGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGN 790 Score = 32.0 bits (72), Expect = 0.037 Identities = 50/313 (15%), Positives = 113/313 (36%), Gaps = 32/313 (10%) Query: 1702 SNNYKSTQDITVIPAEIDIHKS---TFNSHRRSINADNKDSTLLSVKLMDKYGNTIDGKN 1758 SNN ITV+ + + F + + S AD + + + K G Sbjct: 539 SNNV--LLTITVLSNGQVVDQVGVTDFTADKTSAKADGTE-AITYTATVKKNGVAQANVP 595 Query: 1759 VEIKTISGKPNFSDNPLKSVGNGEYQTNVTANTMSDIILTAQAETITIAEPLTIKVAIPK 1818 V +SG S N + G+G+ + ++ ++++A+ +T A + + + Sbjct: 596 VSFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQ 655 Query: 1819 SEIT-FEKPIQQEIYKSTVIDALSYKGVPQNMQVIWSSSDPTVASIDTTSGQISMKKA-- 1875 ++ + E + + DA++Y + M+ S+ V TT G++S Sbjct: 656 TKASITEIKADKTTAVANGQDAITY--TVKVMKGDKPVSNQEVT-FTTTLGKLSNSTEKT 712 Query: 1876 ---GTTIITLQTLGNEQYPSAKNSYPLVIEKAPPKLKVTSPHTIQSIWNDGITHQITAEF 1932 G +TL + + + + ++ P+++ + TI + + + + Sbjct: 713 DTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGTGVKGKL 772 Query: 1933 DNPEVK-----------NTPIHFSSSDTLVATIDSKGNLTAIKPGKTKIVIQSDATDKFL 1981 ++ N + S++ +A++D+ +K K I ++D Sbjct: 773 PTVWLQYGQVNLKASGGNGKYTWRSANPAIASVDASSGQVTLK-EKGTTTISVISSDN-- 829 Query: 1982 ADSQTVDYQQEKA 1994 QT Y Sbjct: 830 ---QTATYTIATP 839
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 28.9 bits (64), Expect = 0.020 Identities = 26/118 (22%), Positives = 43/118 (36%), Gaps = 18/118 (15%) Query: 104 KAQADQKTDALKESIAQKTDELKDSASAKADEIKQSLNNESDKLAGKAEEVKQNANTTAD 163 QAD + + DE A A + + AE KQ + T Sbjct: 1002 NIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETV--------AENSKQESKTVEK 1053 Query: 164 NLKQNASDKAAQLKEDAAKTSDDVK---------QQAQDTKDKALDKADELTDQAKQK 212 N +Q+A++ AQ +E A + +VK Q +TK+ + E K++ Sbjct: 1054 N-EQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEE 1110
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 28.4 bits (63), Expect = 0.027 Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 13/73 (17%) Query: 146 FGYRLEEDNKPGK--LNADKLETE--NIPRGPWYKLLKQGK--------TVTLP-DGRII 192 F + EE+ G L+A+K + +P G YK++ G TVT+ G +I Sbjct: 97 FNKKAEENKAKGDAFLSANKSKPGIVVLPSGLQYKIIDAGTGAKPGKSDTVTVEYTGTLI 156 Query: 193 DGKDYLSTEIKGR 205 DG + STE G+ Sbjct: 157 DGTVFDSTEKAGK 169
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 669 bits (1727), Expect = 0.0 Identities = 217/889 (24%), Positives = 376/889 (42%), Gaps = 64/889 (7%) Query: 8 IDLNVKHKSKQCR--GRSATTLIYFVIIGMASIASDSFAVSKDIEFNSDILDLKDRGNID 65 ++L + ++ QC + + + + A+ + S ++ FN L + D Sbjct: 4 LNLRLYQRNTQCLHIRKHRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVAD 63 Query: 66 LSSFSRAGYITPGKYELIININNNELSGTYRVDYIVPKDDPKASEPCISPILVKQFALRP 125 LS F + PG Y + I +NN + T V + D + PC++ + L Sbjct: 64 LSRFENGQELPPGTYRVDIYLNNGYM-ATRDVTF-NTGDSEQGIVPCLTRAQLASMGLNT 121 Query: 126 EWLKKLTWKDKGNCLN-EASLPGMSLRTDLGSGVFFITLPQAYLEYSSPNWESPSFWDEG 184 + + C+ + + + + D+G +T+PQA++ + + P WD G Sbjct: 122 ASVSGMNLLADDACVPLTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPG 181 Query: 185 IAGLLFDYNVNANVRAPSDGKQKQQITANGTAGANLGVWRFRADWQASYEHTTGVLHSTE 244 I L +YN + N G N +G N+G WR R + SY + S + Sbjct: 182 INAGLLNYNFSGNSVQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGS-K 240 Query: 245 NHWNWDQFYLYRAITKWGARLVMGETYLRSNLLDNFRFTGISLLTDEQMLPPNLRGYAPE 304 N W +L R I +RL +G+ Y + ++ D F G L +D+ MLP + RG+AP Sbjct: 241 NKWQHINTWLERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPV 300 Query: 305 ITGVAKTNAKVTVSQQGRIIYETQIAPGPFRIQDLHD-AVSGRLDVRIEEQDGTIQEYQI 363 I G+A+ A+VT+ Q G IY + + PGPF I D++ SG L V I+E DG+ Q + + Sbjct: 301 IHGIARGTAQVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTV 360 Query: 364 DTANIPYLTRPGRLQYKVSAGKPSRLDHKTEGPIFAMGEFSWGVNNGWSLFGGTLVSKDY 423 +++P L R G +Y ++AG+ + + E P F G+ GW+++GGT ++ Y Sbjct: 361 PYSSVPLLQREGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRY 420 Query: 424 NSASLGFGRDLMMLGAISFDTTHSWATFANENKHYHGSSYRISYSKRFESIDGQITFAGY 483 + + G G+++ LGA+S D T + +T ++++H G S R Y+K I GY Sbjct: 421 RAFNFGIGKNMGALGALSVDMTQANSTLPDDSQH-DGQSVRFLYNKSLNESGTNIQLVGY 479 Query: 484 RFSDRHFMSMDQYLDRRYRYGAQENN--------------------KELYTLTLSKQFPQ 523 R+S + + R E + LT+++Q + Sbjct: 480 RYSTSGYFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGR 539 Query: 524 WGLSTYINYNHQRYWDRPNND-YYNFSLSKYLAIGKFKNINISLSAYRNRFNGNH--DNG 580 + Y++ +HQ YW N D + L+ F++IN +LS + D Sbjct: 540 TS-TLYLSGSHQTYWGTSNVDEQFQAGLNTA-----FEDINWTLSYSLTKNAWQKGRDQM 593 Query: 581 VYFNINLPWRDR-----------ATISYN-SVINKEGNSHNVSYFDRIDDNN--NYRLSA 626 + N+N+P+ A+ SY+ S ++ + + ++N +Y + Sbjct: 594 LALNVNIPFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQT 653 Query: 627 GVSSRGKPSAD----GFFTHYGDVALVTASASHINGDYTSASLSFQGGATLTTKGGDFHR 682 G + G ++ + G SH + D GG G + Sbjct: 654 GYAGGGDGNSGSTGYATLNYRGGYGNANIGYSH-SDDIKQLYYGVSGGVLAHANGVTLGQ 712 Query: 683 SNMPGATRLLIDTQGVSDVPVKSLSAISHTNIFGKAVIPDINHYYRGSASIDLKQLPDNV 742 T +L+ G D V++ T+ G AV+P Y ++D L DNV Sbjct: 713 --PLNDTVVLVKAPGAKDAKVEN-QTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNV 769 Query: 743 EALRSIHQLTLTEGAIGYRQFDVIAGHKAMATVQLAEGGAPPFAATVTTLNGRELGVFND 802 + ++ + T GAI +F G K + T+ PF A VT+ + + G+ D Sbjct: 770 DLDNAVANVVPTRGAIVRAEFKARVGIKLLMTLT-HNNKPLPFGAMVTSESSQSSGIVAD 828 Query: 803 GGKVYLSGINSGDVLYVHW--DGKNQCQL--SIPKLADTQLITSLLLTC 847 G+VYLSG+ + V W + C +P + QL+T L C Sbjct: 829 NGQVYLSGMPLAGKVQVKWGEEENAHCVANYQLPPESQQQLLTQLSAEC 877
>FIMBRIALPAPF#Escherichia coli: P pili tip fibrillum papF protein signature. Length = 167 Score = 55.9 bits (134), Expect = 2e-12 Identities = 54/149 (36%), Positives = 71/149 (47%), Gaps = 17/149 (11%) Query: 49 IPINIKGYVIAHPPCMINEGKTVEVNFGDVLSTRVDGLNYKRLVDYHPSCEQMPINTLKL 108 + INI+G V PPC IN G+ + V+FG++ VD + + SC +L + Sbjct: 21 VQINIRGNVYI-PPCTINNGQNIVVDFGNINPEHVDNSRGEVTKNISISCPYKS-GSLWI 78 Query: 109 SVEGNGTFF-DANALMTNITGLGIRILYQNK----PLKLGQAINFTYPDFPVLE------ 157 V GN N L TNIT GI LYQ K PL LG Y L+ Sbjct: 79 KVTGNTMGVGQNNVLATNITHFGI-ALYQGKGMSTPLTLGNGSGNGYRVTAGLDTARSTF 137 Query: 158 ---AVPVRDFSTLLVGGDFSTTATLRMEY 183 +VP R+ S +L GGDF TTA++ M Y Sbjct: 138 TFTSVPFRNGSGILNGGDFRTTASMSMIY 166
>FIMBRIALPAPF#Escherichia coli: P pili tip fibrillum papF protein signature. Length = 167 Score = 28.1 bits (62), Expect = 0.013 Identities = 32/118 (27%), Positives = 53/118 (44%), Gaps = 18/118 (15%) Query: 6 RIFFFITLL-SSFSLMADETANKATITNSENNLRLFGTLFIPPPCVIQNNDMIDVNFGHQ 64 R+ FI+LL +S +++AD N + G ++IPP C I N I V+FG+ Sbjct: 3 RLSLFISLLLTSVAVLADVQIN------------IRGNVYIPP-CTINNGQNIVVDFGN- 48 Query: 65 LGTSRIDGINYTKTVNYTLQCEENANGWALGLSIIGSASQF-DAAALQTNITDLAVHL 121 + +D T N ++ C + +L + + G+ L TNIT + L Sbjct: 49 INPEHVDNSRGEVTKNISISCPYKSG--SLWIKVTGNTMGVGQNNVLATNITHFGIAL 104
>PF03627#PapG Length = 336 Score = 43.8 bits (103), Expect = 4e-07 Identities = 34/161 (21%), Positives = 65/161 (40%), Gaps = 23/161 (14%) Query: 141 QPNAYGFAEDGYLLPGSICAIAPPP---------VGHCDVLAHSVELDYGNVGENELDNA 191 Q + + + +P ++ P +G C A S+E+ +G++ N +N Sbjct: 180 QRHFASYLGARFKIPYNVAKTLPRENEMLFLFKNIGGCRPSAQSLEIKHGDLSINSANNH 239 Query: 192 VRSQTVNVTCNRDVSLQVVATGMNNRQVPLRNDNSLYADL--------YIND-KSGEEGE 242 +QT++V+C DV + + N + L +N +GE Sbjct: 240 YAAQTLSVSC--DVPANIRFMLLRNTTPTYSHGKKFSVGLGHGWDSIVSVNGVDTGETTM 297 Query: 243 AIFVAKGKMVSIQVSSKLR-TNGHVAPGYFSGSGALILTLP 282 + A + ++I S+L + + PG SGS L++ LP Sbjct: 298 RWYKAGTQNLTIG--SRLYGESSKIQPGVLSGSATLLMILP 336
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 725 bits (1874), Expect = 0.0 Identities = 242/891 (27%), Positives = 389/891 (43%), Gaps = 63/891 (7%) Query: 4 SFKTVCLEKREKRKKHAIR-PVAILIYLIVTGASSLSNSALANSDIEFNADILDLKDKQN 62 S+ + L +R + H + +A + + + + L+++++ FN L + Sbjct: 2 SYLNLRLYQRNTQCLHIRKHRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAV 61 Query: 63 IDLSDFSRAGYIMPGRYEFVVRINNNELPDIYNINYVVPADDPKGSEPCLPPELVRQLGL 122 DLS F + PG Y + +NN + ++ + D +G PCL + +GL Sbjct: 62 ADLSRFENGQELPPGTYRVDIYLNNGYMAT-RDVTFN-TGDSEQGIVPCLTRAQLASMGL 119 Query: 123 KPEWLDKIRFNDNQTCLD-TSSIPGMTINASLGSGNLLLTIPQAYLEYSAPNWDPPSRWD 181 + + + C+ TS I T +G L LTIPQA++ A + PP WD Sbjct: 120 NTASVSGMNLLADDACVPLTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWD 179 Query: 182 DGISGILFDYNVNANVTDPAKGKQRQQVTGLGTLGANLGAWRFRADWQASYQHTTGIPQS 241 GI+ L +YN + N G G N+GAWR R + SY + S Sbjct: 180 PGINAGLLNYNFSGNSVQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGS 239 Query: 242 TENSWKWNQYYLYRAIPQWEARFVMGETYSRSDIFDSFRFTGVHLATDDNMLPPNLRGYA 301 +N W+ +L R I +R +G+ Y++ DIFD F G LA+DDNMLP + RG+A Sbjct: 240 -KNKWQHINTWLERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFA 298 Query: 302 PEVTGVAKTNAKVTISQQGRVIYETQVAPGPFRIQDIND-AVSGKLDVRVEEQDGSVQEF 360 P + G+A+ A+VTI Q G IY + V PGPF I DI SG L V ++E DGS Q F Sbjct: 299 PVIHGIARGTAQVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIF 358 Query: 361 QMDTASIPYLTRPGRVQYKFSAGKPSNIDHNTEGPVFGMGEFSWGVSNGWSLYGGSIVAG 420 + +S+P L R G +Y +AG+ + + E P F G+ GW++YGG+ +A Sbjct: 359 TVPYSSVPLLQREGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLAD 418 Query: 421 DYNALSAGIGRDLMAFGALSFDATHSWAKIPRDDKRYNGGSYRLSYSKRFEAINSQVTFA 480 Y A + GIG+++ A GALS D T + + +P DD +++G S R Y+K + + Sbjct: 419 RYRAFNFGIGKNMGALGALSVDMTQANSTLP-DDSQHDGQSVRFLYNKSLNESGTNIQLV 477 Query: 481 GYRFSERDFMTMDQYLERRYRDGNADNN--------------------KELYTIMFSKQF 520 GYR+S + R N + + + ++Q Sbjct: 478 GYRYSTSGYFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQL 537 Query: 521 PDWGLSTYLNYSHQTYWNKPTND-NYNLSLAKSADIGRFKNINFSLSAFRNK--FNGTND 577 + YL+ SHQTYW D + L + F++IN++LS K + D Sbjct: 538 GRTS-TLYLSGSHQTYWGTSNVDEQFQAGLNTA-----FEDINWTLSYSLTKNAWQKGRD 591 Query: 578 NGVYMNVSMPWGDR-----------ATISYN-TVINKSGNSHNVSYYDRI--DDNSSYRV 623 + +NV++P+ A+ SY+ + ++ Y + D+N SY V Sbjct: 592 QMLALNVNIPFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSV 651 Query: 624 GAGVS----SNGKPSADAYFMHYADAALVTASASHINGEYTSATLSLQGGATLTPKGGAL 679 G + N + A + SH + + + GG G L Sbjct: 652 QTGYAGGGDGNSGSTGYATLNYRGGYGNANIGYSH-SDDIKQLYYGVSGGVLAHANGVTL 710 Query: 680 HRVSRTGSTRLLIDTDGIANIPVKNFGAISHTNMFGKAVLPDINDYYRSSASIDLNRLPE 739 + T +L+ G + V+N T+ G AVLP +Y + ++D N L + Sbjct: 711 GQ--PLNDTVVLVKAPGAKDAKVEN-QTGVRTDWRGYAVLPYATEYRENRVALDTNTLAD 767 Query: 740 NVEALRSIQQLTLTEGAIGYRRFDVIEGQKAMAVIRLKDGTFPPFGASVTTEKGRELGII 799 NV+ ++ + T GAI F G K + + + PFGA VT+E + GI+ Sbjct: 768 NVDLDNAVANVVPTRGAIVRAEFKARVGIKLLMTLT-HNNKPLPFGAMVTSESSQSSGIV 826 Query: 800 NDGGNVYLTGINTGDVLSVRW--SGKEQCKV--LIPTLVENVQISSLLLTC 846 D G VYL+G+ + V+W C +P + ++ L C Sbjct: 827 ADNGQVYLSGMPLAGKVQVKWGEEENAHCVANYQLPPESQQQLLTQLSAEC 877
>FIMBRIALPAPF#Escherichia coli: P pili tip fibrillum papF protein signature. Length = 167 Score = 57.4 bits (138), Expect = 6e-13 Identities = 49/149 (32%), Positives = 75/149 (50%), Gaps = 17/149 (11%) Query: 46 VYINITGNVIAPPPCLINDGKMIEVNFGEVMSTRINDSNYKQPIEYTATCQKRPTNAMKV 105 V INI GNV PP C IN+G+ I V+FG + +++S + + +C + + ++ + Sbjct: 21 VQINIRGNVYIPP-CTINNGQNIVVDFGNINPEHVDNSRGEVTKNISISCPYK-SGSLWI 78 Query: 106 YITGNATGF-DSNALQTNITGLGVRILYQGK------LLGLGSAVKF-------TYPNLP 151 +TGN G +N L TNIT G+ LYQGK LG GS + T + Sbjct: 79 KVTGNTMGVGQNNVLATNITHFGI-ALYQGKGMSTPLTLGNGSGNGYRVTAGLDTARSTF 137 Query: 152 KLEAIPVRDNRETLVGGDFVANATLHVDY 180 ++P R+ L GGDF A++ + Y Sbjct: 138 TFTSVPFRNGSGILNGGDFRTTASMSMIY 166
>FIMBRIALPAPF#Escherichia coli: P pili tip fibrillum papF protein signature. Length = 167 Score = 34.3 bits (78), Expect = 1e-04 Identities = 46/168 (27%), Positives = 67/168 (39%), Gaps = 19/168 (11%) Query: 6 SICLIILLNSTAVMAADSPNLKLFGTLLVPPPCVISNDERIEVFFGKNVGINKVDGINYT 65 S+ + +LL S AV+A N++ G + +PP C I+N + I V FG N+ VD N Sbjct: 5 SLFISLLLTSVAVLADVQINIR--GNVYIPP-CTINNGQNIVVDFG-NINPEHVD--NSR 58 Query: 66 ESVNYTLVCDANLKGWDLGLSIIGPKTQFDE-AALQTNIPDLGIHLTQD---GKPFKLNE 121 V + K L + + G + L TNI GI L Q P L Sbjct: 59 GEVTKNISISCPYKSGSLWIKVTGNTMGVGQNNVLATNITHFGIALYQGKGMSTPLTLGN 118 Query: 122 ------RIAISPD---SPPVIQAVPVKRPGSTLPEGAFEVSATLLAEY 160 R+ D S +VP + L G F +A++ Y Sbjct: 119 GSGNGYRVTAGLDTARSTFTFTSVPFRNGSGILNGGDFRTTASMSMIY 166
>FIMBRIALPAPE#Escherichia coli: P pili tip fibrillum papE protein signature. Length = 173 Score = 36.9 bits (85), Expect = 2e-05 Identities = 51/191 (26%), Positives = 85/191 (44%), Gaps = 32/191 (16%) Query: 2 KIKTLSIRFILGLSVSIGLTSAAFAIPDNLYFHGILVDEPCTIKPGDETVVLDFGNIPDK 61 KI+ L + +LG L S DNL F G L+ CT++ + +++G+I + Sbjct: 3 KIRGLCLPVMLGAV----LMSQHVHAADNLTFKGKLIIPACTVQNAE----VNWGDIEIQ 54 Query: 62 NLYAYKRTPSKLFQLRLSECDLSIGK-SVKITFKGEENQAM--------AGEGFLAISPG 112 NL K F + ++ C S+G V IT G+ ++ +G+G L Sbjct: 55 NL-VQSGGNQKDFTVDMN-CPYSLGTMKVTITSNGQTGNSILVPNTSTASGDGLLIYLYN 112 Query: 113 SQASGIAVGLESENGNALPINKE--TDKMSLTAGDTILNFYAFIQGEPDAIANKSIKRGP 170 S SGI GNA+ + + K++ TA + YA + + + +S++ G Sbjct: 113 SNNSGI--------GNAVTLGSQVTPGKITGTAPARKITLYAKLGYKGNM---QSLQAGT 161 Query: 171 FSAIATFYLNY 181 FSA AT +Y Sbjct: 162 FSATATLVASY 172
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 138 bits (348), Expect = 9e-38 Identities = 88/399 (22%), Positives = 165/399 (41%), Gaps = 17/399 (4%) Query: 23 IALALATFMQVLDSTIANVAIPTIAGNLGASNSQGTWVITSFGVANAISIPITGWLAKRI 82 I L + +F VL+ + NV++P IA + + WV T+F + +I + G L+ ++ Sbjct: 17 IWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQL 76 Query: 83 GEVRLFMWSTALFALTSWLCGISQS-LEMLIFFRVLQGLVAGPLIPLSQSLLLNNYPPAK 141 G RL ++ + S + + S +LI R +QG A L ++ P Sbjct: 77 GIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKEN 136 Query: 142 RNMALALWSVTIVVAPILGPILGGYISDNYHWGWIFFINVPFGVLIIMCISNTLAGRETK 201 R A L + + +GP +GG I+ HW ++ I + + II ++ Sbjct: 137 RGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPM---ITIITVPFLMKLLKKEV 193 Query: 202 TEIKPIDTIGLVLLVVGVGALQIMLDQGKELDWFNSTEIIVLTIIAVVALSFLIVWELTD 261 D G++L+ VG+ + ML F ++ I I++V++ + Sbjct: 194 RIKGHFDIKGIILMSVGI--VFFML--------FTTSYSISFLIVSVLSFLIFVKHIRKV 243 Query: 262 EHPVIDLSLFKSRNFTIGCLTLSLAYMIYFGTIVLLPLLLQEVFGYTATWAGLAAASVGL 321 P +D L K+ F IG L + + G + ++P ++++V + G G Sbjct: 244 TDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGT 303 Query: 322 LPLIIT-PIIGKFGGKVDLRYIISFSFIMFAVCFYWRAYTFEPGMDFATVAWPQFWQGLG 380 + +II I G + Y+++ +V F ++ E F T+ GL Sbjct: 304 MSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGL- 362 Query: 381 VACFFMPLTTMTLSGLPPEKMASASSLSNFLRTLAGAIG 419 + ++T+ S L ++ + SL NF L+ G Sbjct: 363 -SFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTG 400
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 70.6 bits (173), Expect = 2e-15 Identities = 43/257 (16%), Positives = 90/257 (35%), Gaps = 23/257 (8%) Query: 98 EILALDKAKTALANSVRQMHQQIINGRQLKANIVLRETELAKLQNDLRRREVLGERNVIG 157 E L + N R ++ + L + + + + +N + E + E V Sbjct: 215 ERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQEN--KYVEAVNELRV-Y 271 Query: 158 KEELQHAREAVATAKAALDVAKEQYNANQAIILTTPIAQQPSVLQAATEVRNAWLALQRT 217 K +L+ + +AK + + + + IL ++ E+ Q + Sbjct: 272 KSQLEQIESEILSAKEEYQLVTQLF---KNEILDKLRQTTDNIGLLTLELAKNEERQQAS 328 Query: 218 KILSPAEGYVSRRSVQ-VGAQVAPGKPLMAVVPV-TGMWIDANFKETQLANMRIGQPAKI 275 I +P V + V G V + LM +VP + + A + + + +GQ A I Sbjct: 329 VIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAII 388 Query: 276 TTDFYGKKVIYHGRVQGLDMGTGSAFSLLPAQNASGNWIKVVQRLPVRISLDEKEVAEK- 334 + + +G + G + + +V V IS++E ++ Sbjct: 389 KVEAFPYTR--YGYLVG-------KVKNINLDAIEDQRLGLVFN--VIISIEENCLSTGN 437 Query: 335 ---PLRIGLSTEVTVDT 348 PL G++ + T Sbjct: 438 KNIPLSSGMAVTAEIKT 454 Score = 45.6 bits (108), Expect = 2e-07 Identities = 23/178 (12%), Positives = 60/178 (33%), Gaps = 16/178 (8%) Query: 58 VTGNQIMVMPQISGSVTTVYVDNTDYVKAGEPLVQLDDSDEILALDKAKTALANSVRQMH 117 +G + P + V + V + V+ G+ L++L K +++L + Sbjct: 92 HSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQA----R 147 Query: 118 QQIINGRQLKANIVLRETELAKLQNDLRRREVLGERNVIGKEELQHAREAVATAKAALDV 177 + + L +I L + KL ++ + V E + ++ K ++ Sbjct: 148 LEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKEL 207 Query: 178 AKEQYNANQAIILTTPIAQQPSVLQAATEVRNAWLALQRTKILSP--AEGYVSRRSVQ 233 ++ A + +L + + + R S + +++ +V Sbjct: 208 NLDKKRAERLTVLARINRYE----------NLSRVEKSRLDDFSSLLHKQAIAKHAVL 255
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 108 bits (271), Expect = 2e-28 Identities = 85/364 (23%), Positives = 145/364 (39%), Gaps = 12/364 (3%) Query: 11 RNLLVCFIGSFSTVFAMTLMLPFLPLYVEELGVQGHAAIVQWSGVAFSATFITAGLIAPV 70 R L+V + L++P LP + +L G+ + + APV Sbjct: 5 RPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVT--AHYGILLALYALMQFACAPV 62 Query: 71 WGKLGDKYGRKSMLVRASLGMAVTVSLMGMVTNIWQLVGLRLLVGLAGGYSSGATILIAV 130 G L D++GR+ +L+ + G AV ++M +W L R++ G+ G + A IA Sbjct: 63 LGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIAD 122 Query: 131 QAPRERVAWALGIVSCGVMAGNLIGPLAGGWLPDLFGIRNTFFCAGALIFLSFIMTLTLI 190 + A G +S G + GP+ GG + F FF A AL L+F+ L+ Sbjct: 123 ITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFAAAALNGLNFLTGCFLL 181 Query: 191 REDTPKYINTTTKMQV----SWSQLPARFVIVSMLCTGLLLMLANMSIEPIITVYVRTLV 246 E + + S+ V+ +++ ++ L + ++ Sbjct: 182 PESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRF 241 Query: 247 NDPAQITRVAGYVMAAAALGSIISASWLGKLADRIGHLRIITLALAIAGLLLIPQAFVTS 306 + A ++ + A L S+ A G +A R+G R + L + G I AF T Sbjct: 242 HWDATTIGIS--LAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATR 299 Query: 307 GWQLIILRFLMGLALGGL-LPCIAAVIRHHVPEGMIGSILGYSVAAQFAGQFIGPLIGGV 365 GW + L LA GG+ +P + A++ V E G + G A +GPL+ Sbjct: 300 GWMAFPIMVL--LASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTA 357 Query: 366 IGGH 369 I Sbjct: 358 IYAA 361
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 70.4 bits (172), Expect = 8e-17 Identities = 46/188 (24%), Positives = 78/188 (41%), Gaps = 11/188 (5%) Query: 12 IDKNSA-LLVMDFQTTILNNFLPQDR-AEDVIRNTSSLISATRAAGIPIIYVSVEFREGY 69 D N A LL+ D Q ++ F ++ N L + GIP++Y + Sbjct: 26 PDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCVQLGIPVVYTA------- 78 Query: 70 PEVSQNNIIFSSIKD--NGILITNSESSAIHDDIFPQENEIVIIKRRVGAFSFTELEMVL 127 SQN + + D L + I ++ P+++++V+ K R AF T L ++ Sbjct: 79 QPGSQNPDDRALLTDFWGPGLNSGPYEEKIITELAPEDDDLVLTKWRYSAFKRTNLLEMM 138 Query: 128 RTQGIETLILAGVTTSGVILSTVSQAFDLDYRLVIVSDCCADPDHDTHVFLLEKILSQHA 187 R +G + LI+ G+ L T +AF D + V D AD + H LE + A Sbjct: 139 RKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVADFSLEKHQMALEYAAGRCA 198 Query: 188 VVTSSSEI 195 + + Sbjct: 199 FTVMTDSL 206
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 42.1 bits (99), Expect = 2e-06 Identities = 53/261 (20%), Positives = 92/261 (35%), Gaps = 24/261 (9%) Query: 19 ILLMAVATGMVVASNYYAQPLLDSIANYFHISATLAGFIVTTAQLSYALGLMLLVPLG-- 76 + L AV G+++ P+L + S + L YAL P+ Sbjct: 14 VALDAVGIGLIM-------PVLPGLLRDLVHSNDVTAHYGILLAL-YALMQFACAPVLGA 65 Query: 77 --DIFERRSLIVIMTLISASGLLITAMAPNIWLMLIGTALSGMFSVVAQILVPFAATLAA 134 D F RR ++++ +A I A AP +W++ IG ++G+ + + A + Sbjct: 66 LSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITD 125 Query: 135 PHQRGKAVGTIMSGLLLGILLARTASGLMASFTNWQGIFWLASVFLAILAITLWRCLPTY 194 +R + G + + G++ GLM F+ F+ A+ + +T LP Sbjct: 126 GDERARHFGFMSACFGFGMVAGPVLGGLMGGFSP-HAPFFAAAALNGLNFLTGCFLLPES 184 Query: 195 KSQT----NLNYFQLLGSIFKLFATTPV--LRTRSLIGALIFAHFGLLWTSMAFLLASDP 248 L S T V L I L+ LW + D Sbjct: 185 HKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWV----IFGEDR 240 Query: 249 FNYSDAVIGL-FGLVGAAGAL 268 F++ IG+ G +L Sbjct: 241 FHWDATTIGISLAAFGILHSL 261 Score = 32.9 bits (75), Expect = 0.002 Identities = 36/179 (20%), Positives = 67/179 (37%), Gaps = 7/179 (3%) Query: 16 KGLILLMAVATGMVVASNYYAQPLLDSIANYFHISATLAGFIVTTAQLSYALG-LMLLVP 74 + LMAV M + A + + FH AT G + + ++L M+ P Sbjct: 210 TVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGP 269 Query: 75 LGDIFERRSLIVIMTLISASGLLITAMAPNIWLMLIGTALSGMFSVVAQILVPFAATLAA 134 + R +++ + +G ++ A A W+ L + L + Sbjct: 270 VAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGMPALQAMLSRQVD 329 Query: 135 PHQRGKAVGTIMS----GLLLGILLARTASGLMASFTNWQGIFWLASVFLAILAITLWR 189 ++G+ G++ + ++G LL AS T W G W+A L +L + R Sbjct: 330 EERQGQLQGSLAALTSLTSIVGPLLFTAIYA--ASITTWNGWAWIAGAALYLLCLPALR 386
>SURFACELAYER#Lactobacillus surface layer protein signature. Length = 439 Score = 29.3 bits (65), Expect = 0.033 Identities = 20/100 (20%), Positives = 31/100 (31%), Gaps = 4/100 (4%) Query: 18 AATENANTTQNSAQETHNNTDTDND----PWATTDSNTTDTDPWSSSAGGDTGGADADPW 73 A NA TT N+ + NT+ D P + + +D + G TG A Sbjct: 25 AMPVNAATTINADSAINANTNAKYDVDVTPSISAIAAVAKSDTMPAIPGSLTGSISASYN 84 Query: 74 GTGSGTDGSDLSSGTDWLDAMPTESTPDHFNIMDPFNHTL 113 G + S D+ P + T+ Sbjct: 85 GKSYTANLPKDSGNATITDSNNNTVKPAELEADKAYTVTV 124
>PF06340#Vibrio cholerae toxin co-regulated pilus biosynthesis protein F (TcpF) Length = 338 Score = 27.7 bits (61), Expect = 0.005 Identities = 14/48 (29%), Positives = 24/48 (50%), Gaps = 8/48 (16%) Query: 24 DYPTVDDLRRALINKGDRWALALEDGKLLSAVNQSFVQGTYAIKDGDE 71 + PT D + L+N A +GKL +A+NQ ++ G + K+ Sbjct: 128 EIPTRDQIE-TLVN------YA-NEGKLSTALNQEYITGRFLTKENGR 167
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 56.9 bits (137), Expect = 2e-11 Identities = 39/172 (22%), Positives = 78/172 (45%), Gaps = 2/172 (1%) Query: 198 AREREQGTLDQLLVSPLSTWQIFVGKAVPAMVVAAVQGTIVLIIGIFGYQIPFSGSLLLF 257 R Q T + +L + L I +G+ A AA+ G + ++ + SLL Sbjct: 92 GRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAGIGVVAAALGYTQWL-SLLYA 150 Query: 258 YFTMLIYGLSLVGFGLLISALSSTQQQAFIGVFVFMMPAVLLSGYISPVENMPVWLQQAT 317 + + GL+ G++++AL+ + + + P + LSG + PV+ +P+ Q A Sbjct: 151 LPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQTAA 210 Query: 318 WINPIRHFTDITKQIYLKNADITVIWHSLWALIVIAIGTGSIAYYLFCRKIV 369 P+ H D+ + I L + + V H + AL + + ++ L R+++ Sbjct: 211 RFLPLSHSIDLIRPIMLGHPVVDVCQH-VGALCIYIVIPFFLSTALLRRRLL 261
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 47.2 bits (112), Expect = 3e-08 Identities = 39/172 (22%), Positives = 72/172 (41%), Gaps = 2/172 (1%) Query: 211 AREWERGTMEALLSTQITRTELLLSKLIPYQVLGSFVMVLCMLVTVYILGVPYRGSLWIL 270 R + T EA+L TQ+ +++L ++ + +V + + L+ L Sbjct: 92 GRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAGIGVVAAALGYTQWLSLLYAL 151 Query: 271 AGITSLFLATALGMGLLISTLTRNQFNAAMISLNAAFLPAVMLSGFVFEIDSMPFFIQVV 330 I LA A +G++++ L + ++ + P + LSG VF +D +P Q Sbjct: 152 PVIALTGLAFA-SLGMVVTALAPS-YDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQTA 209 Query: 331 TYFIPARYFVSSLQTLFLAGDIPMILMLDMWLLIVSAIFFIGLTALATRRRL 382 F+P + + ++ + L + + L I I F TAL RR L Sbjct: 210 ARFLPLSHSIDLIRPIMLGHPVVDVCQHVGALCIYIVIPFFLSTALLRRRLL 261
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 56.8 bits (137), Expect = 4e-11 Identities = 30/282 (10%), Positives = 92/282 (32%), Gaps = 38/282 (13%) Query: 69 QLLGQLDDAPYINALNKAYGERDSAIASLALMEAGYRSEEIAQAQSDVSLKRAAWQYAEN 128 Q + + + + + + + + L R+E + ++ + ++ Sbjct: 177 QNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAE-RLTVLARINRYENLSRVEKS 235 Query: 129 FYKRQQDLANRKVISAN--------------DLDSARNNRNQAAAALKAAQDKLNQYQNG 174 L +++ I+ + +L ++ Q + + +A+++ Sbjct: 236 RLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQL 295 Query: 175 YRQE---DIDMARGQVLQAKAAVAQAELNLQDTQLTSPAEGTILTRAV-EPGTILSAGSP 230 ++ E + + +A+ E Q + + +P + V G +++ Sbjct: 296 FKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAET 355 Query: 231 VFTVSLTN-PVWVRAYISENHLGEAIPNREVYLYTDS---RKDKPYHGTIGFVSPTAEFT 286 + + + + V A + +G + + ++ + G + ++ A Sbjct: 356 LMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDA--- 412 Query: 287 PKSVETPELRTDLVYRIRVVVTDADDS-------LRQGMPVT 321 + R LV+ + + + + S L GM VT Sbjct: 413 -----IEDQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVT 449 Score = 47.9 bits (114), Expect = 3e-08 Identities = 30/159 (18%), Positives = 52/159 (32%), Gaps = 2/159 (1%) Query: 52 GKLAELQVDEGAPVTKGQLLGQLDDAPYINALNKAYGERDSAIASLALMEAGYRS-EEIA 110 + E+ V EG V KG +L +L K A + RS E Sbjct: 105 SIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNK 164 Query: 111 QAQSDVSLKRAAWQYAENFYKRQQDLA-NRKVISANDLDSARNNRNQAAAALKAAQDKLN 169 + + + +E R L + N N ++ A ++N Sbjct: 165 LPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARIN 224 Query: 170 QYQNGYRQEDIDMARGQVLQAKAAVAQAELNLQDTQLTS 208 +Y+N R E + L K A+A+ + Q+ + Sbjct: 225 RYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVE 263
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 57.7 bits (139), Expect = 2e-12 Identities = 16/68 (23%), Positives = 32/68 (47%) Query: 6 QKKTRGELAKRQLLEAACEIFGKNGPDSATTRQIAQAAKQNIAAIAYYFGSKEGLYLAVA 65 + K + ++ +L+ A +F + G S + +IA+AA AI ++F K L+ + Sbjct: 4 KTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIW 63 Query: 66 QYIADLIR 73 + I Sbjct: 64 ELSESNIG 71
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 128 bits (322), Expect = 2e-40 Identities = 32/153 (20%), Positives = 70/153 (45%), Gaps = 6/153 (3%) Query: 15 LYTRNNVDDSVKLHTIELLQQMVTQFIDLSLITKQAHWNMRGRNFIAVHEMVDGFRDTIN 74 + T N + + L ++ + L + HW ++G +F +HE + D Sbjct: 1 MKTENAKTNQTLV--ENSLNTQLSNWFLLYSKLHRFHWYVKGPHFFTLHEKFEELYDHAA 58 Query: 75 EHTDEFAERLVQLGGTVLGTPQTVSKKTPLKAYPLDIHDVQDHLKALADRYAVVANDIRK 134 E D AERL+ +GG + T + ++ + + + ++AL + Y ++++ + Sbjct: 59 ETVDTIAERLLAIGGQPVATVKEYTEHASITDGGNETS-ASEMVQALVNDYKQISSESKF 117 Query: 135 AI---DEVEDEDTADMFTAASRDLDKFLWFIEA 164 I +E +D TAD+F +++K +W + + Sbjct: 118 VIGLAEENQDNATADLFVGLIEEVEKQVWMLSS 150
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 59.2 bits (143), Expect = 8e-14 Identities = 26/106 (24%), Positives = 42/106 (39%), Gaps = 9/106 (8%) Query: 39 QDEAFIINGIKNDKFHLLVAELEQKIVGFTIAQIQETPLFNCLVQRKYAYIFDIVVDPSV 98 +D+ ++ ++ + + LE +G +I+ +N YA I DI V Sbjct: 51 EDDDMDVSYVEEEGKAAFLYYLENNCIG----RIKIRSNWN-----GYALIEDIAVAKDY 101 Query: 99 RGQGAGALLLNAMKAWAKQQKMTHLELSVLAENADAKRFYQREGLK 144 R +G G LL+ WAK+ L L N A FY + Sbjct: 102 RKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFI 147
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 37.4 bits (87), Expect = 1e-04 Identities = 20/60 (33%), Positives = 31/60 (51%) Query: 504 MTRQKDPSQPRLDNDRNLTLIEVLRAATINAAYALDMDKQIGSLEVGKFADFIVLDRNLF 563 M RQ+ + ++ N + + TIN A A + +IGSLEVGK AD ++ + F Sbjct: 383 MKRQRGRLKEETGDNDNFRVKRYIAKYTINPAIAHGLSHEIGSLEVGKRADLVLWNPAFF 442
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 30.6 bits (69), Expect = 0.012 Identities = 43/261 (16%), Positives = 85/261 (32%), Gaps = 31/261 (11%) Query: 112 IGWASGWTLVLVASWANEVLARLNRPA----LSVAVYAGTGAGIFISGLLAVFILKWQMS 167 + +G T + ++ ++ R +S G AG + GL+ S Sbjct: 105 VAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMG------GFS 158 Query: 168 ATTGWLIYGVLAFICAIYVSYHLPKPWSINREQVKVEPLILTPAMKKLIWGYTFAGFGYI 227 + L + + + LP+ R ++ E L W + Sbjct: 159 PHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPL---ASFRWARGMTVVAAL 215 Query: 228 LPATFLSQMATERFPGSLVAQFVWPIFGASAALCIGIAILTRNVLN--TQLRLA--ITLW 283 + F+ Q+ + P +L F F A IGI++ +L+ Q + + Sbjct: 216 MAVFFIMQLVGQ-VPAALWVIFGEDRFHWDATT-IGISLAAFGILHSLAQAMITGPVAAR 273 Query: 284 LQALGIIIAEWLPTITGLAIGAFLVGGGLMCAVQLAFLRGKELAPDHARYMA-------- 335 L ++ + TG + AF G + + + G P ++ Sbjct: 274 LGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQ 333 Query: 336 ----GLLTTFYAIGQLVGPLV 352 G L ++ +VGPL+ Sbjct: 334 GQLQGSLAALTSLTSIVGPLL 354
>STREPKINASE#Streptococcus streptokinase protein signature. Length = 440 Score = 30.4 bits (68), Expect = 0.005 Identities = 16/43 (37%), Positives = 23/43 (53%), Gaps = 2/43 (4%) Query: 159 PGLGNQWLVLLKDTALVSLISVNDLMLQTQSIANRTQEPFTWY 201 PGL + L LK A+ I+ +L+ Q QSI N+ +T Y Sbjct: 203 PGLKDTKL--LKTLAIGDTITSQELLAQAQSILNKNHPGYTIY 243
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 50.6 bits (121), Expect = 6e-09 Identities = 40/205 (19%), Positives = 78/205 (38%), Gaps = 41/205 (20%) Query: 5 RVLVLGASGHIGQNLIPALIAQGHQVTA---------GARRVDWMMSQGWQNTRCVFVDL 55 + LV GA+G IG ++ L+ GHQV + + + + +DL Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 56 HDPKTLRDVIRNT--DIVYYLVH------SMGDAHNLIEQERQAALNVVDALEESDVKQI 107 D + + D+ + + V+ H S+ + H + LN+++ + ++ + Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 108 IFLS-----ALQHK---------DQPYSPHLVARKLTGEVLRTS-----SIPVTEIRTSM 148 ++ S L K D P S + A K E++ + +P T +R Sbjct: 122 LYASSSSVYGLNRKMPFSTDDSVDHPVSLY-AATKKANELMAHTYSHLYGLPATGLRFFT 180 Query: 149 IVG----PGSAAFEIMRDMVYNLPI 169 + G P A F+ + M+ I Sbjct: 181 VYGPWGRPDMALFKFTKAMLEGKSI 205
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 28.0 bits (62), Expect = 0.048 Identities = 20/99 (20%), Positives = 39/99 (39%), Gaps = 18/99 (18%) Query: 2 LSGLLIILL--PLFIGYLIKLNNRPLLQLANRL-----LSAM--VYVILFLMGVSL---- 48 L G +L+ P+F+ L L+ A LSA Y++ LMGV++ Sbjct: 420 LGGCFPLLIQMPIFLALYYMLMGSVELRQAPFALWIHDLSAQDPYYILPILMGVTMFFIQ 479 Query: 49 -----AMLDNIGENLFSILAYASVFFICTFGANLLFLWL 82 + D + + + + + F F + L+ ++ Sbjct: 480 KMSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYI 518
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 56.4 bits (136), Expect = 7e-11 Identities = 29/140 (20%), Positives = 59/140 (42%), Gaps = 1/140 (0%) Query: 44 GELSKEVTATGKLDAV-RKVDVGAQVSGQLQTLYVKEGDVVKKGDLLAIIDPKKAQNEVA 102 G++ TA GKL R ++ + ++ + VKEG+ V+KGD+L + A+ + Sbjct: 78 GQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTL 137 Query: 103 ESQETNNELMANLQQAKAELRLAQLTYQRQLKLIGTHVIAQEELDRTKTDVEVKKARVAT 162 ++Q + + + + R +L +LKL + + K + +T Sbjct: 138 KTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFST 197 Query: 163 YEAQIRKNQATLDTARTNLQ 182 ++ Q + + LD R Sbjct: 198 WQNQKYQKELNLDKKRAERL 217 Score = 44.8 bits (106), Expect = 4e-07 Identities = 36/215 (16%), Positives = 73/215 (33%), Gaps = 37/215 (17%) Query: 96 KAQNEVAESQETNNELMANLQQAKAELRLAQLTYQRQLKLIGTHVIAQEELDRTKTDVEV 155 +A NE+ + ++ + + AK E +L ++ + ++L +T Sbjct: 263 EAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNE---------ILDKLRQTT----- 308 Query: 156 KKARVATYEAQIRKNQATLDTARTNLQYTRITAPMDGVVTFIKTL-EGQTVIAAQEAPTI 214 + ++ K Q + I AP+ V +K EG V A+ + Sbjct: 309 --DNIGLLTLELAK-------NEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAE--TLM 357 Query: 215 LTLADLDTMLVKAEVSEADVIYLKPDLKASFTVLGAPDKAF---NGKLKDILP-TPEKIN 270 + + + DT+ V A V D+ ++ A V P + GK+K+I E Sbjct: 358 VIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQR 417 Query: 271 DAIFYYARFEVPNEQHLLRLQ-------MTAQVKI 298 + + + + M +I Sbjct: 418 LGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEI 452
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 34.8 bits (80), Expect = 0.001 Identities = 32/114 (28%), Positives = 47/114 (41%), Gaps = 4/114 (3%) Query: 181 NQLARQGKIDPLIGRQAELERTIQVLCR--RRKNNPLLVGESGVGKTAIAEGLAWRIEQN 238 PL+GR A ++ +VL R + ++ GESG GK +A L ++ Sbjct: 128 KLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRR 187 Query: 239 DVPDVMKGCTLYSLD-IGSLLAGTKYRGDFEKRFKALLKTLEKDEKSILFIDEI 291 + P V D I S L G + +G F E+ E LF+DEI Sbjct: 188 NGPFVAINMAAIPRDLIESELFGHE-KGAFTGAQTRSTGRFEQAEGGTLFLDEI 240
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 78.7 bits (194), Expect = 3e-18 Identities = 62/360 (17%), Positives = 121/360 (33%), Gaps = 76/360 (21%) Query: 52 ISTKTPGRIDTILVKEGDFVKAGEVLATMDTRTLKEQLHEVQAQLEQAKSSV-------- 103 I + I+VKEG+ V+ G+VL + + + Q+ L QA+ Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSR 158 Query: 104 ------------------------------MTAESALSQRQSEQVAAQAVVRQRIAELDA 133 + S Q+++ + + ++ AE Sbjct: 159 SIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLT 218 Query: 134 SV--------------KRLNRSRALVKTKAISIQQLDDDIARTEGARAAVEAAKAQVTAT 179 + RL+ +L+ +AI+ + + + A + K+Q+ Sbjct: 219 VLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQI 278 Query: 180 IAAIDSAKSGIIQ-------------AKTKVDAATATERRIMAELD--DSILKAPRNGRV 224 + I SAK +T + T E S+++AP + +V Sbjct: 279 ESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKV 338 Query: 225 -QYRVAEPGEVLGAGGRVLNMVDLSDVY-MTFFLPTEAAGKAALGSDVHIILDAAPHIVI 282 Q +V G V+ ++ +V D +T + + G +G + I ++A P+ Sbjct: 339 QQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRY 398 Query: 283 PAKTTYVASVAQFTPKTVETDNERLKLMFRVRARI-SPELLEK-HLEYVKTGLPGRAYIR 340 V V +E ++RL L+F V I L + +G+ A I+ Sbjct: 399 G---YLVGKVKNINLDAIE--DQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIK 453
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 48.4 bits (115), Expect = 1e-08 Identities = 41/175 (23%), Positives = 74/175 (42%), Gaps = 7/175 (4%) Query: 197 AALIREREHGTIEHLLVMPVTPFEIMLSKI-WSMGLVVLLASAMSLVLVVKSLLHVPIEG 255 AA R T E +L + +I+L ++ W+ L + + +V Sbjct: 89 AAFGRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAGIGVVAAALGYTQWL--- 145 Query: 256 SVLLFMCGVALSLFATTSIGIFLGTMARSMPQFGLLMIMVLLPLNMLSGGMTSRESMPQF 315 S+L + +AL+ A S+G+ + +A S F +V+ P+ LSG + + +P Sbjct: 146 SLLYALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIV 205 Query: 316 VQDVMQTMPTTHFVSLAQAILY--RGADFSIVWPQFIVLIIIGSVFFALALLRFR 368 Q + +P +H + L + I+ D + I+I F + ALLR R Sbjct: 206 FQTAARFLPLSHSIDLIRPIMLGHPVVDVCQHVGALCIYIVI-PFFLSTALLRRR 259
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 92.2 bits (229), Expect = 8e-24 Identities = 34/129 (26%), Positives = 65/129 (50%), Gaps = 1/129 (0%) Query: 1 MTPYNILIVEDEKEILRFVRLALENEGFRVYDASECQRGLIEAASRKPDLVILDLGLPDK 60 MT IL+ +D+ I + AL G+ V S A+ DLV+ D+ +PD+ Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 DGLCFIQDFRQ-WSSTPIIVLSARDSEQDKVDALDAGADDYLTKPFGMSELLARVRASLR 119 + + ++ P++V+SA+++ + A + GA DYL KPF ++EL+ + +L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 120 RFVKQETET 128 ++ ++ Sbjct: 121 EPKRRPSKL 129
>PF06580#Sensor histidine kinase Length = 349 Score = 32.1 bits (73), Expect = 0.010 Identities = 13/68 (19%), Positives = 30/68 (44%), Gaps = 7/68 (10%) Query: 763 DKHPLQIDIPADLLLYCDSLLIERVLTNLLENAVKYTASQTKLG----IKATVEEDQIHV 818 D+ + I ++ ++ + L+EN +K+ +Q G +K T + + + Sbjct: 238 DRLQFENQINPAIMDVQVPPML---VQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTL 294 Query: 819 EVWDEGAG 826 EV + G+ Sbjct: 295 EVENTGSL 302
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 103 bits (257), Expect = 1e-28 Identities = 65/246 (26%), Positives = 106/246 (43%), Gaps = 20/246 (8%) Query: 2 IIFITGASAGFGEAIARHFINHGHKVIGTARRLDKLQALHQELGDL-FYP--LQLDVTDK 58 I FITGA+ G GEA+AR + G + +KL+ + L + DV D Sbjct: 10 IAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDS 69 Query: 59 KAVSEIYHQLPEQWRSIDVLVNNAGLALGLSTADKANLDDWDTMIETNNKGLVHVTRALL 118 A+ EI ++ + ID+LVN AG+ L + ++W+ N+ G+ + +R++ Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGV-LRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 119 PSMVERNVGHIINISSTAASWPYMGGNVYGATKAFVKQFSLGLRADLQGKKIRVTDIEPG 178 M++R G I+ + S A P Y ++KA F+ L +L IR + P Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP- 187 Query: 179 LVGGTEFSLVR-FKGDTDKVEQTYAGADA-----------LTPEDVAQAV-FWTATLPAH 225 G TE + D + EQ G+ P D+A AV F + H Sbjct: 188 --GSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGH 245 Query: 226 VNINTL 231 + ++ L Sbjct: 246 ITMHNL 251
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 27.5 bits (61), Expect = 0.035 Identities = 9/31 (29%), Positives = 15/31 (48%), Gaps = 3/31 (9%) Query: 106 VVIEGNGGWRYLLDDNTFYSDWVAKEKIPVV 136 + + G+GGW L D + ++ PVV Sbjct: 55 IFLSGDGGWATL--DKAV-GGILQQQGWPVV 82
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 29.1 bits (65), Expect = 0.032 Identities = 7/41 (17%), Positives = 18/41 (43%) Query: 126 FLAAIDTFFQRYQSRVERLTAISITMNAIVDPISGVIYSSP 166 LA + F + + R + A + + ++DP +++ Sbjct: 154 HLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPN 194
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 48.7 bits (116), Expect = 3e-08 Identities = 72/365 (19%), Positives = 141/365 (38%), Gaps = 55/365 (15%) Query: 64 LPILSKEFSVTPATSSLALSLSTGLMACGLLITGPLSDAFGRKNVMVIALFCAAFFTLLS 123 LP ++ +F+ PA+++ + + G + G LSD G K +++ + F +++ Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 124 AMMNSWTGILI-TRALVGLSLSGVAAVAMTYLSEEIHPAYLALSMGLYISGNSIGGMSGR 182 + +S+ +LI R + G + A+ M ++ I + GL S ++G G Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 183 VITGVLSDYYSWR-------VSVI--------------------ILGIFALVAAIIFWRI 215 I G+++ Y W +++I I GI + I+F+ + Sbjct: 157 AIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFML 216 Query: 216 LPTSQH-------------FRPATLKPRNLLITTKLHFRDKGLPLLFIEGGLLMG---GF 259 TS F K + + L ++ + + GG++ G GF Sbjct: 217 FTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGL-GKNIPFMIGVLCGGIIFGTVAGF 275 Query: 260 VTLFNYIGYRLLDAPYSLTQTTVGLISI--VYLSGTYSASKAGLLTNKYGLGKVFIAGVS 317 V++ Y ++ + L+ +G + I +S G+L ++ G V GV+ Sbjct: 276 VSMVPY----MMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVT 331 Query: 318 MMLAGILI---TLFDSLAIIFIGMLILTTGFFAAHAVASSWVGRRAKRGRAQAS-SLYLF 373 + L L + + I ++ + G V S+ V K+ A A SL F Sbjct: 332 FLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNF 391 Query: 374 TYYAG 378 T + Sbjct: 392 TSFLS 396
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 426 bits (1098), Expect = e-152 Identities = 182/351 (51%), Positives = 258/351 (73%), Gaps = 1/351 (0%) Query: 1 MSRPAKISINLDALSHNLSVIKSKAQGSKVWSVVKADAYGHGLSCVWPALSHTDGFALIE 60 M+RP + S++L AL NLS+++ A ++VWSVVKA+AYGHG+ +W A+ TDGFAL+ Sbjct: 1 MTRPIQASLDLQALKQNLSIVRQAATHARVWSVVKANAYGHGIERIWSAIGATDGFALLN 60 Query: 61 LDKAIMLREQGWVGPILLLEGFFKPDDVYLLERYSLTTVVHADWQFEAIEQAQLERPINI 120 L++AI LRE+GW GPIL+LEGFF D+ + +++ LTT VH++WQ +A++ A+L+ P++I Sbjct: 61 LEEAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQNARLKAPLDI 120 Query: 121 YLKLNSGMNRLGYRPEDYQQAIQRAKGITNIGSIVQMSHFANAD-TGLNMATQKQIIDSS 179 YLK+NSGMNRLG++P+ Q+ + + N+G + MSHFA A+ +I ++ Sbjct: 121 YLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHFAEAEHPDGISGAMARIEQAA 180 Query: 180 MVNDLPRCLANSAAILFEPQTHHSWVRPGIILYGVSPSGVWQDIADFDLQPVMTFNSEVL 239 + R L+NSAA L+ P+ H WVRPGIILYG SPSG W+DIA+ L+PVMT +SE++ Sbjct: 181 EGLECRRSLSNSAATLWHPEAHFDWVRPGIILYGASPSGQWRDIANTGLRPVMTLSSEII 240 Query: 240 AIQSVKKGEQIGYGSRYTAQRDMRIAVVACGYADGYPRHAPDGTPVIVKGHKTQLVGRIS 299 +Q++K GE++GYG RYTA+ + RI +VA GYADGYPRHAP GTPV+V G +T VG +S Sbjct: 241 GVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAPTGTPVLVDGVRTMTVGTVS 300 Query: 300 MDMLTIDVTDLPDVEHGSPVELWGNQLPVDEVALACGTIGYELLCAIAPRV 350 MDML +D+T P G+PVELWG ++ +D+VA A GT+GYEL+CA+A RV Sbjct: 301 MDMLAVDLTPCPQAGIGTPVELWGKEIKIDDVAAAAGTVGYELMCALALRV 351
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 31.7 bits (72), Expect = 0.005 Identities = 11/31 (35%), Positives = 19/31 (61%), Gaps = 1/31 (3%) Query: 1 MKVIILGG-GVIGVTSAWYLVQQGHEVIVVD 30 MK ++ G G IG + L++ GH+V+ +D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGID 31
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 45.6 bits (108), Expect = 3e-07 Identities = 67/445 (15%), Positives = 145/445 (32%), Gaps = 60/445 (13%) Query: 53 LGMSEAEAITVFAAFTALVYGFVAIGGWLGDKILGTKRVIVLGAIVLAIGYAMVAFSDHD 112 A V AF A+ G L D++ G KR+++ G I+ G + Sbjct: 44 FNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQL-GIKRLLLFGIIINCFGSVIGFVGHSF 102 Query: 113 KDMIYWGLATIAVGNGLFKANPSSLLAT-CYEKDDPQLDGAFTMYYMSINVGSFLSMLAT 171 ++ G F A ++A +++ AF + + +G + Sbjct: 103 FSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRG---KAFGLIGSIVAMGEGVGPAIG 159 Query: 172 PWLAANYGWDVAFALSVVGMLITLANFMLCRGWIKDKGSRPDFEPLNYLKLLLTLVGIVA 231 +A W + +IT+ +K + + GI+ Sbjct: 160 GMIAHYIHWSYLLLI----PMITIITVPFLMKLLKKEVRIKGH---------FDIKGIIL 206 Query: 232 LTAVSTWLLHNNEVATWSLAIISLGIILIFARETFMMKGVAR--------------RKMI 277 ++ + + + S I+S+ LIF + ++ V ++ Sbjct: 207 MSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKH---IRKVTDPFVDPGLGKNIPFMIGVL 263 Query: 278 VAFLLMVEAVVFFVLYDQMPTSLNFFAIHNVEHAILGFSVEPEQFQSLNPFWIMLASPLL 337 ++ F + +P + +H + A +G + F ++ + Sbjct: 264 CGGIIFGTVAGFVSM---VPYMMKD--VHQLSTAEIGSVI---------IFPGTMSVIIF 309 Query: 338 AAIYNFMGDKLPMPYKFTVGMFLSATAFLVLPLGASMANEAGIVSSWWLVASYGFQSIGE 397 I + D+ Y +G+ + +FL + + + +V G S + Sbjct: 310 GYIGGILVDRRGPLYVLNIGVTFLSVSFLTA---SFLLETTSWFMTIIIVFVLGGLSFTK 366 Query: 398 LMISGLGLAMVAQLVPQRLMGFIMGAWFLTSAAAAIIAGKVASL-----MAVPEDVQNAH 452 +IS + + + Q M + FL+ I G + S+ +P +V Sbjct: 367 TVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQ-- 424 Query: 453 ASLEIYSSVFLQIGIVTGVIALLML 477 S +YS++ L + + L+ L Sbjct: 425 -STYLYSNLLLLFSGIIVISWLVTL 448
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 41.7 bits (98), Expect = 3e-06 Identities = 28/131 (21%), Positives = 49/131 (37%), Gaps = 15/131 (11%) Query: 79 TALGTVKAV-NSVTVTSRVEGQLMALHFTEGQQVNQGDLLAEIDPRPFEVQLAQAKGQLA 137 TA G + S + + + EG+ V +GD+L ++ A+ Sbjct: 85 TANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTAL-------GAEADTL 137 Query: 138 KDQATLANARLDLARYQKLAK-------THLVSQQELDNQAALVKQSEASISIDKAAINN 190 K Q++L ARL+ RYQ L++ L E Q ++ S+ K + Sbjct: 138 KTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFST 197 Query: 191 AQLQLTYSKIT 201 Q Q ++ Sbjct: 198 WQNQKYQKELN 208 Score = 38.3 bits (89), Expect = 4e-05 Identities = 23/126 (18%), Positives = 56/126 (44%), Gaps = 4/126 (3%) Query: 126 EVQLAQAKGQLAKDQATLANARLDLARYQKLAKTHLVSQQELDNQAALVKQSEASISIDK 185 E + +A +L ++ L ++ + + LV+Q + ++Q+ +I + Sbjct: 258 ENKYVEAVNELRVYKSQLEQIESEILSAK--EEYQLVTQLFKNEILDKLRQTTDNIGLLT 315 Query: 186 AAINNAQLQLTYSKITAPISGRV-GLKQVDVGNYISGGSSTPIVVINQMDPVDVLFTLPE 244 + + + S I AP+S +V LK G ++ T +V++ + D ++V + Sbjct: 316 LELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTA-ETLMVIVPEDDTLEVTALVQN 374 Query: 245 QDLSQV 250 +D+ + Sbjct: 375 KDIGFI 380
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 831 bits (2148), Expect = 0.0 Identities = 281/1036 (27%), Positives = 496/1036 (47%), Gaps = 29/1036 (2%) Query: 13 SRLFILRPVATTLFMVAILLAGIVGYRMLPVSALPEVDYPTIQVVTLYPGANPEVMTSAV 72 + FI RP+ + + +++AG + LPV+ P + P + V YPGA+ + + V Sbjct: 2 ANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTV 61 Query: 73 TAPLERQFGQMSGLKQMSSQS-SGGASVITLMFQLTLPLDVAEQEVQAAINAATNLLPTD 131 T +E+ + L MSS S S G+ ITL FQ D+A+ +VQ + AT LLP + Sbjct: 62 TQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE 121 Query: 132 LPYPPIYSKVNPADPPVLTLAVTSSVLPMTQ--LQDMVETRISQKISQVNGVGLVSLAGG 189 + I S + ++ S TQ + D V + + +S++NGVG V L G Sbjct: 122 VQQQGI-SVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 190 QRPAVRVKLNAQAAASYGLDSETIRVAINNANVNSAKGSLDGP------TRSVTLSANDQ 243 Q A+R+ L+A Y L + + N A G L G + ++ A + Sbjct: 181 QY-AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 244 MKSLDDYRKLIV-SYKNGAPIRLADIATIEQAPENNQLGAWANNQQAIIINVQRQPGVNV 302 K+ +++ K+ + +G+ +RL D+A +E EN + A N + A + ++ G N Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 303 IETTDNIRNLLPDLVSNLPKSVNVEILTDRTTTIRASVKDVQFELGLAIALVVMVIYLFL 362 ++T I+ L +L P+ + V D T ++ S+ +V L AI LV +V+YLFL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 363 RNGVATLIPSIAVPLSLVGTFAVMYFCGFSVNNLTLMALTIATGFVVDDAIVVIENISRY 422 +N ATLIP+IAVP+ L+GTFA++ G+S+N LT+ + +A G +VDDAIVV+EN+ R Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 423 L-ERGDKPLTAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAIL 481 + E P A K +I ++ + L AV IP+ F G G ++R+F+IT+ A+ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 482 ISAVVSLTLTPMMCARLLKPESQIKH---NRFEMACERFFEKMIAVYAVWLKRVLNHQWI 538 +S +V+L LTP +CA LLKP S H F F+ + Y + ++L Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 539 TLGVALSTLALTVLLYLFIPKGFFPLQDNGLLQGTIETSQSISYQAMVEKQQQVVEKLID 598 L + +A V+L+L +P F P +D G+ I+ + + + QV + + Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 599 DPA--VENIASFVGIDGSNATLNTGRLQITLKPLDQRDSR---IDEIIPRLQARVASIAG 653 + VE++ + G S N G ++LKP ++R+ + +I R + + I Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRD 659 Query: 654 ITLYLQPTQDLTIDTQVSRTQYQFTLQ---ATSLDELAYWVPKL-SQALQESPELTDISS 709 ++ P I + T + F L D L +L A Q L + Sbjct: 660 --GFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRP 717 Query: 710 DWQADGMMAYINVDRDSASRLGISMSAIDNALYNAFGQRLISTIYTQANQYRVVLEQNMH 769 + D + VD++ A LG+S+S I+ + A G ++ + ++ ++ + Sbjct: 718 NGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAK 777 Query: 770 NSEGLQALSAVHLTGKEGAMVPLLSIASVEQRLAPLSINHQEQFPATTFSFNVAKDASLE 829 + + +++ G MVP + + + P+ A S Sbjct: 778 FRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSG 837 Query: 830 AAVNAVKQAEEQIAMPKDITTQFQGATLAFESALSSTLWLIIAAIVAMYIVLGVLYESFI 889 A+ ++ + +P I + G + + + L+ + V +++ L LYES+ Sbjct: 838 DAMALMENLASK--LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWS 895 Query: 890 HPITILSTLPTAGVGALLALMAAGNELDIIAIIGIILLIGIVKKNAIMMIDFALAAEREQ 949 P++++ +P VG LLA + D+ ++G++ IG+ KNAI++++FA ++ Sbjct: 896 IPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKE 955 Query: 950 GLSPYEAIYQACLLRFRPILMTTMAALLGALPLMLSTGVGAELRQPLGVCMVGGLIMSQI 1009 G EA A +R RPILMT++A +LG LPL +S G G+ + +G+ ++GG++ + + Sbjct: 956 GKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATL 1015 Query: 1010 LTLFTTPVIYLLFDKL 1025 L +F PV +++ + Sbjct: 1016 LAIFFVPVFFVVIRRC 1031
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 846 bits (2187), Expect = 0.0 Identities = 277/1030 (26%), Positives = 508/1030 (49%), Gaps = 30/1030 (2%) Query: 6 LFIQRPVATTLLSLAISLCGALGFMLLPVAPLPQVDYPVINIYASLPGASPETMASSVAT 65 FI+RP+ +L++ + + GAL + LPVA P + P +++ A+ PGA +T+ +V Sbjct: 4 FFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQ 63 Query: 66 PLERSLGRIAGIDEMTSSSA-LGSTSITLVFDLNKDINTAARDVQAALNASQSLLPSGMP 124 +E+++ I + M+S+S GS +ITL F D + A VQ L + LLP + Sbjct: 64 VIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQ 123 Query: 125 SRPRYYKSNPSDAPIMILTLTSETQNT--GELYDLASTRLAQKISQIEGVSEVSVGGGSL 182 + S + +M+ S+ T ++ D ++ + +S++ GV +V + G Sbjct: 124 -QQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQY 182 Query: 183 PAVRVALNPDALFNQNVSLDDVRKAISQSNVRRPQGFIHNDEN------RWQIQTNDELS 236 A+R+ L+ D L ++ DV + N + G + I Sbjct: 183 -AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK 241 Query: 237 KAQDYRPIIVHYNQD-AIVRLSDVAQVTDSVQNARAAGMSGGEPAILLVIRREAGANIIE 295 +++ + + N D ++VRL DVA+V +N G+PA L I+ GAN ++ Sbjct: 242 NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALD 301 Query: 296 TVNRIRDELPELRELLPASVNLKVAQDRTPTIRASLAEVERALAIAVALVILVVFLFLRS 355 T I+ +L EL+ P + + D TP ++ S+ EV + L A+ LV LV++LFL++ Sbjct: 302 TAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQN 361 Query: 356 GRATLIPAVAVPVSLIGTFSAMYLCGFSLNNLSLMALTVATGFVVDDAIVVLENISRHI- 414 RATLIP +AVPV L+GTF+ + G+S+N L++ + +A G +VDDAIVV+EN+ R + Sbjct: 362 MRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 415 ENGLKPKQAALKGVSEVGFTVLSMSISLVAVFIPLLLMDGLVGRLFKEFAITLTTAIGIS 474 E+ L PK+A K +S++ ++ +++ L AVFIP+ G G ++++F+IT+ +A+ +S Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 475 LFVSLTLTPMMCAHLLKGIKPKAQSHLRGFGKLIFR----LQQGYSVTLQAALRHKRWIM 530 + V+L LTP +CA LLK + + + GF Y+ ++ L + Sbjct: 482 VLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYL 541 Query: 531 AIFITTLGLNAYLYISAPKTFFPDQDTGRLMGFVRADQSISFQSMKEKMTRFMQ-----E 585 I+ + L++ P +F P++D G + ++ + + ++ + + E Sbjct: 542 LIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNE 601 Query: 586 INADKDVDSVTGFTGGGRI-NSGFMFISLNPLSERT---DSANQVINRLRIKLANEPGAT 641 + V +V GF+ G+ N+G F+SL P ER +SA VI+R +++L Sbjct: 602 KANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGF 661 Query: 642 LFLMPVQDVRAGGRQANASYQFT-LLADDLSELRKW-EPLIRKALGELPELVDVNSDKED 699 + + + G ++ L + L+ A LV V + + Sbjct: 662 VIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLE 721 Query: 700 KGAEMALTYDRDTMSQLGINVSDANNLLNNAFGQRQISTIYAPLNQYKVVMEVSEQYTQD 759 A+ L D++ LG+++SD N ++ A G ++ K+ ++ ++ Sbjct: 722 DTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRML 781 Query: 760 VSALDKMYVMNTQGERIPLSAFASWYPANAPLSVNHQGLSAASTIAFNVPEGYTLSDAIN 819 +DK+YV + GE +P SAF + + + + I G + DA+ Sbjct: 782 PEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMA 841 Query: 820 AIERTMTELGVPNTVRGTFAGTAQIFQETIKSQLILILAAIVTVYIVLGVLYESYIHPLT 879 +E ++L P + + G + + + L+ + V V++ L LYES+ P++ Sbjct: 842 LMENLASKL--PAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVS 899 Query: 880 ILSTLPSAGVGALLALRLFDTPFSLIALIGIMLLIGIVKKNAIIMVDFAITAQREGKLSA 939 ++ +P VG LLA LF+ + ++G++ IG+ KNAI++V+FA + Sbjct: 900 VMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGV 959 Query: 940 QEAIIQASLLRFRPIIMTTLAALFGALPLMLSSGDGAELRQPLGITIVGGLLMSQLLTLY 999 EA + A +R RPI+MT+LA + G LPL +S+G G+ + +GI ++GG++ + LL ++ Sbjct: 960 VEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIF 1019 Query: 1000 TTPIIYLFFD 1009 P+ ++ Sbjct: 1020 FVPVFFVVIR 1029
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 78.3 bits (193), Expect = 6e-19 Identities = 26/123 (21%), Positives = 61/123 (49%), Gaps = 1/123 (0%) Query: 9 SILIVEDEPKLAQLLIDYLQASDYQTQWLADGTEVIQHIKQSHYDLVLLDLMLPGKDGIT 68 +IL+ +D+ + +L L + Y + ++ + + I DLV+ D+++P ++ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 69 LCKELRQ-FSDIPIIMVTAKTEEVDRLLGLEIGADDYICKPYSPREVVARVKTLLRRYYR 127 L +++ D+P+++++A+ + + E GA DY+ KP+ E++ + L R Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 128 PQD 130 Sbjct: 125 RPS 127
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 104 bits (261), Expect = 7e-27 Identities = 68/179 (37%), Positives = 98/179 (54%), Gaps = 8/179 (4%) Query: 292 SSVASHAQPSSMMQAQMHFPSMPTPMLNAQIGTPEWQQQLNQQIVMFSRNGLQKAELRLH 351 S V + A P P++ P+L+A +G+ EWQQ L+Q I +F+R G Q AELRLH Sbjct: 205 SPVTAAASPLITPHQTQPLPTVAAPVLSAPLGSHEWQQSLSQHISLFTRQGQQSAELRLH 264 Query: 352 PEELGSLHIRMKIEDGQAQLHLASQNGQVRTVLENSLHHLRQALSENGIQLTQSQVSSDS 411 P++LG + I +K++D QAQ+ + S + VR LE +L LR L+E+GIQL QS +S +S Sbjct: 265 PQDLGEVQISLKVDDNQAQIQMVSPHQHVRAALEAALPVLRTQLAESGIQLGQSNISGES 324 Query: 412 HDGWQQQNMSDSSQFSGNGADNHQRSEGNSMQLASETAQKITLTPQELASARGGVDIFA 470 G QQ S Q NH+ G + + ++ Q + GVDIFA Sbjct: 325 FSGQQQAA---SQQQQSQRTANHEPLAGE-----DDDTLPVPVSLQGRVTGNSGVDIFA 375
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 312 bits (802), Expect = e-108 Identities = 74/295 (25%), Positives = 146/295 (49%), Gaps = 11/295 (3%) Query: 4 NILSQAEIDALLNDDTSGDDAQKSANREPAIAKDPNEPDIQPYDPNTQRRVVRERLQSLE 63 +LSQ EID LL +SGD S I+ I YD + +E++++L Sbjct: 3 EVLSQDEIDQLLTAISSGD---ASIEDARPISD---TRKITLYDFRRPDKFSKEQMRTLS 56 Query: 64 IINERFARQFRMGLFNMLRRSPDITVGGIKIHPYHDFARNLPVPTNLNLVHLKPLRGTAL 123 +++E FAR L LR + V + Y +F R++P P+ L ++ + PL+G A+ Sbjct: 57 LMHETFARLTTTSLSAQLRSMVHVHVASVDQLTYEEFIRSIPTPSTLAVITMDPLKGNAV 116 Query: 124 FTFEPNLVYIAVDNLFGGDGRFPIPVEGREFTNTEQRIINKMLKLALDAYRDAWDSIFKI 183 +P++ + +D LFGG G+ V+ R+ T+ E ++ ++ L R++W + + Sbjct: 117 LEVDPSITFSIIDRLFGGTGQ-AAKVQ-RDLTDIENSVMEGVIVRILANVRESWTQVIDL 174 Query: 184 QVEYVRSEMQVKFTNITSSPNDIVVTTPFQVEIGSMVGEFSICIPFAMIEPLRERLINPP 243 + + E +F I P+++VV + ++G G + CIP+ IEP+ +L + Sbjct: 175 RPRLGQIETNPQFAQIV-PPSEMVVLVTLETKVGEEEGMMNFCIPYITIEPIISKLSSQF 233 Query: 244 IENL--RQEDSVWLDSLVNQVKHSELELVANFTDIPLRLSKVLTLKKGDVLPIDK 296 + R + ++ L +++ ++++VA + L + +L L+ GD++ + Sbjct: 234 WFSSVRRSSTTQYMGVLRDKLSTVDMDVVAEVGSLRLSVRDILGLRVGDIIRLHD 288
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 146 bits (370), Expect = 1e-48 Identities = 93/137 (67%), Positives = 112/137 (81%), Gaps = 1/137 (0%) Query: 1 MSDENRPTD-NSQSAEDMWADAMEQQTGKSQDNSSDVFEHLLPEDDTLNHLSDINLIMDI 59 MSD N P+D N+ + +D+WADA+ +Q + +++D L D + DI+LIMDI Sbjct: 1 MSDMNNPSDENTGALDDLWADALNEQKATTTKSAADAVFQQLGGGDVSGAMQDIDLIMDI 60 Query: 60 PVKLTVELGRTKMTIKKLLSLSQGSVVSLDGLAGEPLDILINGYLIAQGEVVVVSDKYGI 119 PVKLTVELGRT+MTIK+LL L+QGSVV+LDGLAGEPLDILINGYLIAQGEVVVV+DKYG+ Sbjct: 61 PVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGV 120 Query: 120 RITDIITPSERMRRLSR 136 RITDIITPSERMRRLSR Sbjct: 121 RITDIITPSERMRRLSR 137
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 300 bits (770), Expect = e-105 Identities = 181/241 (75%), Positives = 214/241 (88%) Query: 16 LFASVLILSLLPSHAFAQFPSVISHPLPGGGQSWSLPVQTLIFITALGFIPAVLLMMTSF 75 L + ++L L+ AFAQ P + S PLPGGGQSWSLPVQTL+FIT+L FIPA+LLMMTSF Sbjct: 5 LSVAPVLLWLITPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLMMTSF 64 Query: 76 TRIIIVLGLLRNALGTPSAPPNQVVLGLALFMTFFIMAPVFDKIYQDAYLPFSEDKITFE 135 TRIIIV GLLRNALGTPSAPPNQV+LGLALF+TFFIM+PV DKIY DAY PFSE+KI+ + Sbjct: 65 TRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEKISMQ 124 Query: 136 QALDNGSQPLRQFMMQQTRETDLALFARLADAPAFETRDSVPMRILVPAYITSELKTAFQ 195 +AL+ G+QPLR+FM++QTRE DL LFARLA+ + ++VPMRIL+PAY+TSELKTAFQ Sbjct: 125 EALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELKTAFQ 184 Query: 196 IGFMIFIPFLIIDLVVASVLMALGMMMVPPATVSLPFKLMLFVLVDGWQLILGSLAQSFF 255 IGF IFIPFLIIDLV+ASVLMALGMMMVPPAT++LPFKLMLFVLVDGWQL++GSLAQSF+ Sbjct: 185 IGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLAQSFY 244 Query: 256 N 256 + Sbjct: 245 S 245
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 64.4 bits (157), Expect = 1e-17 Identities = 22/78 (28%), Positives = 40/78 (51%) Query: 4 ESVLALGTEAMKIALSLAGPLLLSALVTGLVISMLQAATQINEMTLSFIPKILAVLAAIL 63 + ++ G +A+ + L L+G + A + GL++ + Q TQ+ E TL F K+L V + Sbjct: 2 DDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLF 61 Query: 64 VAGPWMLSLLLDYMHNLF 81 + W +LL Y + Sbjct: 62 LLSGWYGEVLLSYGRQVI 79
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 170 bits (432), Expect = 2e-54 Identities = 145/258 (56%), Positives = 197/258 (76%) Query: 1 MITLTSEILNGYISDFFWPFVRILALFSTAPLFSEKQTPKKFRIGLAFLTTALIAPGLPQ 60 M+ +TSE +++ +FWP +R+LAL STAP+ SE+ PK+ ++GLA + T IAP LP Sbjct: 1 MLQVTSEQWLSWLNLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPA 60 Query: 61 SQVPLFSIMAFWVLIQQILIGTILGLSMQLAFASVRHAGEVIGLQMGLSFATFVDPSGGP 120 + VP+FS A W+ +QQILIG LG +MQ AFA+VR AGE+IGLQMGLSFATFVDP+ Sbjct: 61 NDVPVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHL 120 Query: 121 NMPILARIFNMLTMLLFMVFDGHLWLLSVLADTFYVVPIGNQTFNSLGILTLVQSGGTIF 180 NMP+LARI +ML +LLF+ F+GHLWL+S+L DTF+ +PIG + NS L L ++G IF Sbjct: 121 NMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLIF 180 Query: 181 INGMMLAMPLITLLLVLNLSLGILNRMTPQLSVFVVGFPLTLTIGMLALSLIMPALPVFT 240 +NG+MLA+PLITLLL LNL+LG+LNRM PQLS+FV+GFPLTLT+G+ ++ +MP + F Sbjct: 181 LNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFC 240 Query: 241 ERVFSDTFNRITLILQQL 258 E +FS+ FN + I+ +L Sbjct: 241 EHLFSEIFNLLADIISEL 258
>FLAGELLIN#Flagellin signature. Length = 507 Score = 34.2 bits (78), Expect = 5e-04 Identities = 35/151 (23%), Positives = 63/151 (41%), Gaps = 19/151 (12%) Query: 15 NITSSQSRWMTEGNKISSGRRVEKPSDDPMAASQAVMVKQSEARNQQYATARGFAKNSMS 74 N+ SQS + ++SSG R+ DD AA QA+ N+ + +G + S + Sbjct: 16 NLNKSQSSLSSAIERLSSGLRINSAKDD--AAGQAIA-------NRFTSNIKGLTQASRN 66 Query: 75 LQMSLS---------SQMVNITTKIQETLVAAGNDGALSDEDRASLAEQLSGLKDQLVGI 125 +S +++ N +++E V A N G SD D S+ +++ +++ + Sbjct: 67 ANDGISIAQTTEGALNEINNNLQRVRELSVQATN-GTNSDSDLKSIQDEIQQRLEEIDRV 125 Query: 126 GNTKDGVGRYVFAGFQTDKPPFVADKTGKIT 156 N G V + K A+ IT Sbjct: 126 SNQTQFNGVKVLSQDNQMKIQVGANDGETIT 156
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 362 bits (930), Expect = e-121 Identities = 235/546 (43%), Positives = 338/546 (61%), Gaps = 3/546 (0%) Query: 3 NNLINTAMSGLNAAQAAMSTISNNIANQKVNWYNRQMTVFNENGGTMTSNGYIGNGVNVS 62 ++LIN AMSGLNAAQAA++T SNNI++ V Y RQ T+ + T+ + G++GNGV VS Sbjct: 1 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVS 60 Query: 63 RIHREYNEFLAGQMNRAVTKQSALNSYNKNISQINNLLADKGNDVSSAIDDFFTSLPNVT 122 + REY+ F+ Q+ A T+ S L + + +S+I+N+L+ + +++ + DFFTSL + Sbjct: 61 GVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLV 120 Query: 123 NNAEDNPARTTILGKAEAMVNMFNKADQSLRDLEKDINSQVTNTTKNINEYSKQIAKLNQ 182 +NAED AR ++GK+E +VN F DQ LRD +K +N + + IN Y+KQIA LN Sbjct: 121 SNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLND 180 Query: 183 EISRSQGF-NGAEPNDLLDQRDRLIQELNTLVDVQVTQQDGGFVNVSFANGLPLVAGTRS 241 +ISR G GA PN+LLDQRD+L+ ELN +V V+V+ QDGG N++ ANG LV G+ + Sbjct: 181 QISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTA 240 Query: 242 YEVSAIPSSKNSERLVVGYSNGIDEVREVDAKRINGGELGGAYRSRNEVLDASRNQLNQL 301 +++A+PSS + R V Y +G E+ K +N G LGG R++ LD +RN L QL Sbjct: 241 RQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQL 300 Query: 302 ALVLGDQFNKQHEQGFDLNGDKGDKFFNLGGAHTMPNGKNKGDATFDVKYTDTREVKAAD 361 AL + FN QH+ GFD NGD G+ FF +G + N KNKGD TD V A D Sbjct: 301 ALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGDVAIGATVTDASAVLATD 360 Query: 362 YTVKYEGGKWNVTVEPGNRKFTATPNATTGELEFEGMSIKVNGAAQEGDSIVVQSVGNVI 421 Y + ++ +W VT N FT TP+A G++ F+G+ + G DS ++ V + I Sbjct: 361 YKISFDNNQWQVTRLASNTTFTVTPDA-NGKVAFDGLELTFTGTPAVNDSFTLKPVSDAI 419 Query: 422 AGMSVAISDPSKIAAAGTKDSGPSDNENMKKLFELPDEKLIDGKA-TIAGGYGSLISMVG 480 M V I+D +KIA A +D+G SDN N + L +L G A + Y SL+S +G Sbjct: 420 VNMDVLITDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIG 479 Query: 481 NKVNTAQVDYDAQNAITSSILTQQQSVSGVNLDEEYGEMYRIQEYYMANAKVIQTANTMF 540 NK T + Q + + + QQQS+SGVNLDEEYG + R Q+YY+ANA+V+QTAN +F Sbjct: 480 NKTATLKTSSATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIF 539 Query: 541 DAIMQV 546 DA++ + Sbjct: 540 DALINI 545
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 264 bits (675), Expect = 2e-89 Identities = 150/318 (47%), Positives = 223/318 (70%), Gaps = 14/318 (4%) Query: 13 ISTPAYDSNALNKLKYQVGQNADQQGLRQVAQQLEGVFVQMMLKSMREAIPQESMFNSES 72 +++ A+D+ +LN+LK + G++ +R VA+Q+EG+FVQMMLKSMR+A+P++ +F+SE Sbjct: 8 LASAAWDAQSLNELKAKAGEDPAAN-IRPVARQVEGMFVQMMLKSMRDALPKDGLFSSEH 66 Query: 73 TKMYTSLYDQQIAQDLSK-KGLGFADMIEKQLSAKVTM-EPSELAGKTPMPLDSSDIFQS 130 T++YTS+YDQQIAQ ++ KGLG A+M+ KQ++ + + E S A PL++ +Q+ Sbjct: 67 TRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEESTPAAPMKFPLETVVRYQN 126 Query: 131 MPTQALGQLYRAMQPLQNAVESTVGKLKGLSESSASFAAKLLGPAKQATQGTGIHHLLVV 190 QAL QL + P +N +S G S +F A+L PA+ A+Q +G+ H L++ Sbjct: 127 ---QALSQLVQKAVP-RNYDDSLPG-------DSKAFLAQLSLPAQLASQQSGVPHHLIL 175 Query: 191 AQAALESGWGKREILTGDGKPSYNLFGIKAGRYWKGPVTNIMTTEVIDGKSIKMRDNFRV 250 AQAALESGWG+R+I +G+PSYNLFG+KA WKGPVT I TTE +G++ K++ FRV Sbjct: 176 AQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRV 235 Query: 251 YGSYVEAIQDYLRLLTESPRYAKVPQAKTPEQAAYHIQEAGYATDPGYAKKLVSIIGQLK 310 Y SY+EA+ DY+ LLT +PRYA V A + EQ A +Q+AGYATDP YA+KL ++I Q+K Sbjct: 236 YSSYLEALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQMK 295 Query: 311 GQGEQVAKTYTHDLSELF 328 ++V+KTY+ ++ LF Sbjct: 296 SISDKVSKTYSMNIDNLF 313
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 384 bits (988), Expect = e-135 Identities = 148/351 (42%), Positives = 208/351 (59%), Gaps = 9/351 (2%) Query: 19 SAHAERIRDLTSVEGVRENALIGYGLVVGLDGTGDQTMQTPFTTQSLNNMLSQLGITVPA 78 A RI+D+ S++ R+N LIGYGLVVGL GTGD +PFT QS+ ML LGIT Sbjct: 25 QADTSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFTEQSMRAMLQNLGITTQG 84 Query: 79 GTNMQLKNVAAVMVTAKLPPFGRTGQSIDVVVSSLGNAKSLRGGTLLMTPLKGVDSQVYA 138 G + KN+AAVMVTA LPPF G +DV VSSLG+A SLRGG L+MT L G D Q+YA Sbjct: 85 GQS-NAKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRGGNLIMTSLSGADGQIYA 143 Query: 139 VAQGNIVVGGSGASAGGSSVKVNQLAGGRISNGAIIERELPSQFGQTGLLNLQLNEENFT 198 VAQG ++V G A +++ R+ NGAIIERELPS+F + L LQL +F+ Sbjct: 144 VAQGALIVNGFSAQGDAATLTQGVTTSARVPNGAIIERELPSKFKDSVNLVLQLRNPDFS 203 Query: 199 LAQSIADAINKLR----GVGTALPLDARTVQLRVPLGKSEQVRFLADVQNLEVKRVIADA 254 A +AD +N G A P D++ + ++ P ++ R +A+++NL V+ A Sbjct: 204 TAVRVADVVNAFARARYGDPIAEPRDSQEIAVQKPRV-ADLTRLMAEIENLTVE-TDTPA 261 Query: 255 KVIINARTGSVVMNRDVVLGSCAIAQGNLSVTVDSQVNVSQPNTPFAGGSTVVSRNTSVN 314 KV+IN RTG++V+ DV + A++ G L+V V V QP PF+ G T V T + Sbjct: 262 KVVINERTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQP-APFSRGQTAVQPQTDIM 320 Query: 315 VNEKGGSLQKVNASASLNEVIRSLNALGATPTDLMSILQAMESAGCLRARL 365 ++G + V L ++ LN++G +++ILQ ++SAG L+A L Sbjct: 321 AMQEGSKVAIVE-GPDLRTLVAGLNSIGLKADGIIAILQGIKSAGALQAEL 370
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 268 bits (687), Expect = 2e-93 Identities = 165/220 (75%), Positives = 187/220 (85%) Query: 27 TALLVLTLAGCAQIPEKPLVEGHTTAIPTAPTTPAPNGSIFQATQPVYFGYQPLFEDRRP 86 ++LLVL+L GCA IP PLV+G T+A P TP NGSIFQ+ QP+ +GYQPLFEDRRP Sbjct: 12 SSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINYGYQPLFEDRRP 71 Query: 87 RNIGDTLTITLQENVSASKNSSANASRNGKAGFLASITPRFLEGLLGNSRTDMGMEGNSE 146 RNIGDTLTI LQENVSASK+SSANASR+GK F PR+L+GL GN+R D+ G + Sbjct: 72 RNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNARADVEASGGNT 131 Query: 147 FGGKGGANANNTFKGTITVTVDQLLANGNLHVVGEKQIAINQGTEFIRFSGVVNPRTISG 206 F GKGGANA+NTF GT+TVTVDQ+L NGNLHVVGEKQIAINQGTEFIRFSGVVNPRTISG Sbjct: 132 FNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRFSGVVNPRTISG 191 Query: 207 SNTVNSTQVADARIEYIGDGYINEAQSMGWLQRFFLNVSP 246 SNTV STQVADARIEY+G+GYINEAQ+MGWLQRFFLN+SP Sbjct: 192 SNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSP 231
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 43.4 bits (102), Expect = 4e-07 Identities = 11/41 (26%), Positives = 22/41 (53%) Query: 220 ETSNVNVAEELVNMIQTQRAYEINSKAISTSDQMLQKLTQL 260 S VN+ EE N+ + Q+ Y N++ + T++ + L + Sbjct: 505 SISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545 Score = 42.6 bits (100), Expect = 8e-07 Identities = 18/88 (20%), Positives = 34/88 (38%), Gaps = 14/88 (15%) Query: 4 SLWIAKTGLDAQQTNMDVISNNLANVSTNGFKRQRAVFEDLLYQTIRQPGAMTSEQTNAP 63 + A +GL+A Q ++ SNN+++ + G+ RQ + M + Sbjct: 3 LINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTI--------------MAQANSTLG 48 Query: 64 SGLQIGTGVRPVATERLHSQGNLAQTNG 91 +G +G GV +R + Q Sbjct: 49 AGGWVGNGVYVSGVQREYDAFITNQLRA 76
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 39.9 bits (93), Expect = 2e-05 Identities = 15/48 (31%), Positives = 28/48 (58%) Query: 359 LTNNALEASNVDMSQELVNMIVAQRNYQSNAQTIKTQDQILQTLVSMR 406 L+N S V++ +E N+ Q+ Y +NAQ ++T + I L+++R Sbjct: 499 LSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR 546 Score = 39.2 bits (91), Expect = 3e-05 Identities = 25/60 (41%), Positives = 32/60 (53%), Gaps = 4/60 (6%) Query: 2 SFSQAVSGLNAAAANLDTIGNNISNSATYGFKGATVSFAD----VFAGSGAGLGVKVSGI 57 + A+SGLNAA A L+T NNIS+ G+ T A + AG G GV VSG+ Sbjct: 3 LINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVSGV 62
>PF05860#haemagglutination activity domain. Length = 117 Score = 62.9 bits (153), Expect = 2e-14 Identities = 21/105 (20%), Positives = 37/105 (35%), Gaps = 3/105 (2%) Query: 43 NDDTGKTQIEVINTNQDGT-AHIYYNRLDVGNLGLSL-KNNAEAELIINEVVSKDFSILR 100 N T + Q G+ + V G + N + II+ V S + Sbjct: 14 NITTEGNTRIIERGTQAGSNLFHSFQEFSVPTSGTAFFNNPTNIQNIISRVTGGSVSNID 73 Query: 101 GELELQGKKATVVIANPNGISCRDCSFSGINDIKLIAGSSTGKFS 145 G + A + + NPNGI + I + + ++ KF+ Sbjct: 74 GLIRANA-TANLFLINPNGIIFGQNARLDIGGSFVGSTANRLKFA 117
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 361 bits (929), Expect = e-126 Identities = 105/343 (30%), Positives = 171/343 (49%), Gaps = 3/343 (0%) Query: 8 EKTEEPTPHKREKAKKDGQIVRSKELSSVLMILGGVSLLWMSGRFITRELYAMLTEGFTF 67 EKTE+PTP K A+K GQ+ +SKE+ S +I+ ++L + ++ Sbjct: 4 EKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLML--IPA 61 Query: 68 NHHIIGNENLLIPRFASLMKQAVFALSPVFLGLVLVAIGGSAVLGGINFSSKSIKFDPKK 127 + L +++ + + P+ L+AI V G S ++IK D KK Sbjct: 62 EQSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDIKK 121 Query: 128 WNPISGLKRIFSMNALAELFKAILKSLFVGLAATVFLWHNWNDILHLITLPPLSALANAM 187 NPI G KRIFS+ +L E K+ILK + + + + + N +L L T Sbjct: 122 INPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLLG 181 Query: 188 QLLIFAVYIAVFMLIPMVAFDIIFQIRSHLKKLRMTRQEIKDEFKQQEGDPQLKARIRQQ 247 Q+L + I + + D F+ ++K+L+M++ EIK E+K+ EG P++K++ RQ Sbjct: 182 QILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKRRQF 241 Query: 248 QHEMSRRRMMADVPKADVIVTNPTHYAVALQYN-DKMVAPKVLAKGAGAIALKIKEIGAE 306 E+ R M +V ++ V+V NPTH A+ + Y + P V K A +++I E Sbjct: 242 HQEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIAEE 301 Query: 307 HRIPLLEAPPLARALYRHSEIGQAIPATLYAAVAEVLAWVYQL 349 +P+L+ PLARALY + + IPA A AEVL W+ + Sbjct: 302 EGVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQ 344
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 85.3 bits (211), Expect = 1e-22 Identities = 31/105 (29%), Positives = 52/105 (49%), Gaps = 3/105 (2%) Query: 7 RFLVVDDFSTMRRIVRNLLKELGFMNVEEAEDGADALAKLQSSAYDFVITDWNMPNMDGL 66 LV DD + +R ++ L G+ +V + A + + D V+TD MP+ + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGY-DVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 67 ELLKNIRSDAGLATLPVLMVTAEAKKENIIAAAQSGASGYVVKPF 111 +LL I+ LPVL+++A+ I A++ GA Y+ KPF Sbjct: 64 DLLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPF 106
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.9 bits (158), Expect = 1e-13 Identities = 38/168 (22%), Positives = 74/168 (44%), Gaps = 11/168 (6%) Query: 1 MNKITVLCVDDSALMRQIMREIINSH-HDMEVVDCAPDPIVARDLIKKFNPQVLTLDVEM 59 M T+L DD A +R ++ + ++ +D+ + A I + ++ DV M Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAAT---LWRWIAAGDGDLVVTDVVM 57 Query: 60 PRMDGIDFLEKLMRLRPMPVVMVSSLTAKGS-EVTLKALELGAVDFVTKPQLGLREGMLA 118 P + D L ++ + RP V+V ++A+ + +KA E GA D++ KP L E + Sbjct: 58 PDENAFDLLPRIKKARPDLPVLV--MSAQNTFMTAIKASEKGAYDYLPKP-FDLTELIGI 114 Query: 119 YSELIAEKIRAAAQARISRHETKTLPSKSLSFTPMISSEKLIAVGAST 166 +AE R ++ + L +S + + +++A T Sbjct: 115 IGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIY---RVLARLMQT 159
>PF06580#Sensor histidine kinase Length = 349 Score = 34.5 bits (79), Expect = 0.001 Identities = 47/283 (16%), Positives = 106/283 (37%), Gaps = 51/283 (18%) Query: 302 AKIWAIQHRFIIGLSLGAIILLVFNQ-IW-ISYLVRRRSHQLEQAHIHLREQKEALEQAQ 359 A I F + L+L I +V +W + Y +QA I + ++AQ Sbjct: 103 AFINTKPVAFTLPLALSIIFNVVVVTFMWSLLYFGWHFFKNYKQAEIDQWKMASMAQEAQ 162 Query: 360 RLNILGEMASGFAHELNQPLSAIKSYAQGSAIRLEKENKNHPLLPALRQIDHQAQRGADI 419 + + ++ H + L+ I++ LE K +L +L +++ Sbjct: 163 LMALKAQINP---HFMFNALNNIRALI------LEDPTKAREMLTSL----------SEL 203 Query: 420 IR-NLRLWVGKQSANSDTVPLSEQNVAQCIEHIWRLLRIDEKYPQVTLITKIDKHDTLY- 477 +R +LR +N+ V L+++ + + L++ + L + + + Sbjct: 204 MRYSLRY------SNARQVSLADE-----LTVVDSYLQLASIQFEDRLQFENQINPAIMD 252 Query: 478 --LPETLLEQILSNLITNSL--QAGTKVLQISTHKAPDRLLIVIKDDAGGMSHSQLEQPF 533 +P L++ ++ N I + + + + K + + +++ + Sbjct: 253 VQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKN------ 306 Query: 534 SPFQTTKTEGLGLGLVICQRLLNSQG--ADIHIENQKDKQNNV 574 T ++ G GL V +RL G A I + ++ K N + Sbjct: 307 ----TKESTGTGLQNV-RERLQMLYGTEAQIKLSEKQGKVNAM 344
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 81.8 bits (202), Expect = 2e-20 Identities = 29/122 (23%), Positives = 52/122 (42%) Query: 2 PTIHLVDDDLAVTDACQFLLESLGYAAQVWNDSEYFLHNIDLYQQGVVLLDMRMPKADGR 61 TI + DDD A+ L GY ++ +++ I +V+ D+ MP + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 QVHQYLIEKHSTLAVIFLTGHGDIPMAVEEIKKGAIDFLQKPIDSNALLSALKSAFTETA 121 + + + L V+ ++ A++ +KGA D+L KP D L+ + A E Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 122 TR 123 R Sbjct: 124 RR 125
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 121 bits (305), Expect = 5e-33 Identities = 77/359 (21%), Positives = 138/359 (38%), Gaps = 11/359 (3%) Query: 14 LYIVWFGCFLTGAGFSLIMPFLPLYVEELGIKDHESLNLWTGVAFSITFLFSAIAAPFWG 73 L ++ L G LIMP LP + +L + G+ ++ L AP G Sbjct: 7 LIVILSTVALDAVGIGLIMPVLPGLLRDLVHS--NDVTAHYGILLALYALMQFACAPVLG 64 Query: 74 KLSDRKGRKLMLLRSALGMAIVMVLIGFAQNIWQLLILRALLGVLGGFVPNANALIATQV 133 LSDR GR+ +LL S G A+ ++ A +W L I R + G+ G A A IA Sbjct: 65 ALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADIT 124 Query: 134 PVKKSGWALGTLSTGAVSGALIGPLIGGILADLYGLRPVFFITAAVLFICFIVTLFFVSE 193 + G +S G + GP++GG++ + FF AA+ + F+ F + E Sbjct: 125 DGDERARHFGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFAAAALNGLNFLTGCFLLPE 183 Query: 194 NFTPVSKKDALSTQQVFSSLKNKRL---VICLFFTTMIIQVATGSVTPILTLYIRD-LAG 249 + + +S + R V L I+Q+ + ++ D Sbjct: 184 SHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHW 243 Query: 250 SISNLAFISGVIASVPGIAALISAPRFGKLGDRIGPDKVLIFTLGLSIFMLIPMALVSNY 309 + + + +A + R+G + L+ + I +A + Sbjct: 244 DATTIGISLAAFGILHSLAQAMITGPVAA---RLGERRALMLGMIADGTGYILLAFATRG 300 Query: 310 WELGALRFLLGAVNAAMLPAVQTLILYNITPAIAGRIFSYNQALRDVGNVTGPLMGAFV 368 W + LL + M PA+Q ++ + G++ AL + ++ GPL+ + Sbjct: 301 WMAFPIMVLLASGGIGM-PALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAI 358 Score = 61.8 bits (150), Expect = 1e-12 Identities = 46/189 (24%), Positives = 76/189 (40%), Gaps = 6/189 (3%) Query: 214 KNKRLVICLFFTTMIIQVATGSVTPILTLYIRDLAGSISNLAFISGVIASVPGIAALISA 273 N+ L++ + T + V G + P+L +RDL S +++ G++ ++ + A Sbjct: 3 PNRPLIV-ILSTVALDAVGIGLIMPVLPGLLRDLVHS-NDVTAHYGILLALYALMQFACA 60 Query: 274 PRFGKLGDRIGPDKVLIFTLGLSIFMLIPMALVSNYWELGALRFLLGAVNAAMLPAVQTL 333 P G L DR G VL+ +L + MA W L R + G A AV Sbjct: 61 PVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATG--AVAGA 118 Query: 334 ILYNITPAIA-GRIFSYNQALRDVGNVTGPLMGAFVAANYGFRAVFYFTAAVVFFNLIYS 392 + +IT R F + A G V GP++G + A F+ AA+ N + Sbjct: 119 YIADITDGDERARHFGFMSACFGFGMVAGPVLGGL-MGGFSPHAPFFAAAALNGLNFLTG 177 Query: 393 WISFRTPQR 401 + Sbjct: 178 CFLLPESHK 186
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 33.3 bits (76), Expect = 0.002 Identities = 30/173 (17%), Positives = 60/173 (34%), Gaps = 10/173 (5%) Query: 32 SFYGIRPLLILFMAATVYEGGMDIPREQASAIVGIFAGGVYLTSLPGGWLADNWLGQRLA 91 SF+ + ++L ++ + P + + F + + G L+D +RL Sbjct: 23 SFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLL 82 Query: 92 VWYGSIFIALGHLSIALSAFWSQNLFFI---GLLLIVLGTGLFKTCVTVMVGTLYKKDDT 148 ++ I ++ F + F + + G F V V+V K+ Sbjct: 83 LFGIIINCF-----GSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKE-- 135 Query: 149 RRDGGFSLFYMGINMGSFIAPLITGFLVRDYGWHWGFGIGGIGMLVALLIFRF 201 R F L + MG + P I G + W + I I ++ + + Sbjct: 136 NRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKL 188
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 206 bits (525), Expect = 3e-65 Identities = 89/354 (25%), Positives = 155/354 (43%), Gaps = 30/354 (8%) Query: 43 SWIEISRSALDFNVKKVQSLLGKQSSLCAVLKGDAYGHDLSLVAPIMIENNVQCIGVTNN 102 + AL N+ V+ + + +V+K +AYGH + + + + + N Sbjct: 5 IQASLDLQALKQNLSIVRQA-ATHARVWSVVKANAYGHGIERIWSAIGATD--GFALLNL 61 Query: 103 QELKEVRDLGFKGRLMRVRNAT-EQEMAQATNYNVEELIGDLDMAKRLDAIAKQQNKVIP 161 +E +R+ G+KG ++ + Q++ + + + K L + Sbjct: 62 EEAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQNAR--LKAPLD 119 Query: 162 IHLALNSGGMSRNGLEVDNKSGLEKAKQISQLANLKVVGIMSHYPE-EDVNKVREDLARF 220 I+L +NSG M+R G + D L +Q+ +AN+ + +MSH+ E E + + +AR Sbjct: 120 IYLKVNSG-MNRLGFQPDRV--LTVWQQLRAMANVGEMTLMSHFAEAEHPDGISGAMARI 176 Query: 221 KQQSQKVLEVMGLERNNVTLHMANTFATITVPESWLDMVRVGGIFYG-------DTIAST 273 +Q ++ + ++N+ AT+ PE+ D VR G I YG IA+T Sbjct: 177 EQAAEGL---------ECRRSLSNSAATLWHPEAHFDWVRPGIILYGASPSGQWRDIANT 227 Query: 274 DYKRVMTFKSNIASINYYPKGNTVGYDRTYTLKRDSVLANIPVGYADGYRRVFSNAGHAL 333 + VMT S I + G VGY YT + + + + GYADGY R L Sbjct: 228 GLRPVMTLSSEIIGVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAPTGTPVL 287 Query: 334 IAGQRVPVLGKTSMNTVMVDITSLNNIKPGDEVVFFGKQGNSEITAEEIEDISG 387 + G R +G SM+ + VD+T G V +GK EI +++ +G Sbjct: 288 VDGVRTMTVGTVSMDMLAVDLTPCPQAGIGTPVELWGK----EIKIDDVAAAAG 337
>BONTOXILYSIN#Bontoxilysin signature. Length = 1196 Score = 29.9 bits (67), Expect = 0.021 Identities = 8/61 (13%), Positives = 16/61 (26%), Gaps = 8/61 (13%) Query: 338 DWTVIIPGVVPHFFVGATAGVFGNATGGRRGAILGAFAQGLLITFLPVFLLPVLGDIGIA 397 ++ + T+ F GA LI+ P + I+ Sbjct: 584 GINEVVLWFGKALNILNTSNSFVEEY-----QDSGA---ISLISKKDNLREPNIEIDDIS 635 Query: 398 N 398 + Sbjct: 636 D 636
>ENTSNTHTASED#Enterobactin synthetase component D signature. Length = 234 Score = 27.3 bits (60), Expect = 0.033 Identities = 23/97 (23%), Positives = 34/97 (35%), Gaps = 14/97 (14%) Query: 81 ALESARREAEEELGIAGVP-FAEHGQFYYDDESCRVWGSLFSC-------VSHGPFALQP 132 A A A E+G+ VP + Q + D ++GS+ C +S + Sbjct: 52 AGRIAAVHALREVGVRTVPGMGDKRQPLWPDG---LFGSISHCATTALAVISRQRIGIDI 108 Query: 133 EEI---EEVCWLTPLEITERCDEFTPDSLKALSLWLT 166 E+I L P I + SL L LT Sbjct: 109 EKIMSQHTATELAPSIIDSDERQILQASLLPFPLALT 145
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 46.3 bits (110), Expect = 5e-08 Identities = 53/296 (17%), Positives = 91/296 (30%), Gaps = 63/296 (21%) Query: 1 MNILITGGTGLIGRALICQLA-------------------LDKHNITVLSRSPQKVYSHF 41 M L+TG G IG + +L L + + +L++ + + Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHK-- 58 Query: 42 CNEMACWTHLDDKENLNQFDAVINLAGEPIADKRWTPEQKQTLVNSRCKLTQKLVDLIKA 101 ++A + D F+ V R++ E +S +++ + Sbjct: 59 -IDLADREGMTDLFASGHFERVFISPHR--LAVRYSLENPHAYADSNLTGFLNILEGCRH 115 Query: 102 SDSPPSVLISGSAVGFYGDQGENNVTEETPPKDEFTHQLCAKWENIALDAQT-------P 154 + + S S+V YG + + + + K N L A T P Sbjct: 116 NKIQHLLYASSSSV--YGLNRKMPFSTDDSVDHPVSLYAATKKAN-ELMAHTYSHLYGLP 172 Query: 155 LTRVCLLRTGIVLSTKGGALPKMSPPF--KLGLGGK----LGNGKQYMPWIHIDDMVNAI 208 T LR V G P M+ K L GK GK + +IDD+ AI Sbjct: 173 ATG---LRFFTVYGPWGR--PDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAI 227 Query: 209 VFLLNNNNTQGA------------------FNLTAPHPVQNKAFTTTLAHVLKRPA 246 + L + +N+ PV+ + L L A Sbjct: 228 IRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEA 283
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 29.8 bits (67), Expect = 0.038 Identities = 13/133 (9%), Positives = 42/133 (31%), Gaps = 23/133 (17%) Query: 216 QRKSPWHLNIASDNYGQKNSGRWLIRTNASLDSPLGLSDFVSLNANITTDNPNTRFNRAY 275 + P + + Y ++ + ++ LG + + L+ + T + + + Sbjct: 509 IQVKPKFTDYYNLAYNKRG------KLQLTVTQQLGRTSTLYLSGSHQTYWGTSNVDEQF 562 Query: 276 TLLYSIPYGGFTFSSFGSYSEYQFHQKLQTRTVSLYGDTTQVGI-------RGDYAFSRS 328 + + ++ S T+ G + + + S+S Sbjct: 563 QAGLNTAFEDINWTLSYS----------LTKNAWQKGRDQMLALNVNIPFSHWLRSDSKS 612 Query: 329 QKQIDTLNIQVTH 341 Q + + + ++H Sbjct: 613 QWRHASASYSMSH 625
>PF05860#haemagglutination activity domain. Length = 117 Score = 86.8 bits (215), Expect = 3e-22 Identities = 27/131 (20%), Positives = 41/131 (31%), Gaps = 21/131 (16%) Query: 32 IVPDAGHQGPDVSAVNGGTQVINIVTPNNEGISHNQYQDFNVGKPGAVFNNALEAGQSQL 91 I PD G T++I T + H+ +Q+F+V G F N Sbjct: 3 ITPDTTLPINSNITTEGNTRIIERGTQAGSNLFHS-FQEFSVPTSGTAFFN--------- 52 Query: 92 AGHLNANSNLNGQAASLILNEVVSRNPSFLLGQQEVFGIAAEYVLSNPNGITCDGCGFIN 151 N I++ V + S + G A L NPNGI ++ Sbjct: 53 ----------NPTNIQNIISRVTGGSVSNIDGLIRANA-TANLFLINPNGIIFGQNARLD 101 Query: 152 TSRSSLVVGNP 162 S + Sbjct: 102 IGGSFVGSTAN 112
>SECA#SecA protein signature. Length = 901 Score = 1365 bits (3535), Expect = 0.0 Identities = 755/901 (83%), Positives = 823/901 (91%), Gaps = 1/901 (0%) Query: 1 MLGKIVTKIFGSRNERAIRRMRKVVAQINQLEPEFEKLTDDELKAKTDEFRERLKKGEKE 60 ML K++TK+FGSRN+R +RRMRKVV IN +EPE EKL+D+ELK KT EFR RL+KGE Sbjct: 1 MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVL 60 Query: 61 EDILPEAFATVREASKRVFGMRHFDVQLIGGMVLNDRCIAEMRTGEGKTLTATLPAYLNA 120 E+++PEAFA VREASKRVFGMRHFDVQL+GGMVLN+RCIAEMRTGEGKTLTATLPAYLNA Sbjct: 61 ENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNA 120 Query: 121 LSGKGVHVVTVNDYLAQRDAENNRPLFEFLGLSVGINLPNMAPPAKREAYNADITYGTNN 180 L+GKGVHVVTVNDYLAQRDAENNRPLFEFLGL+VGINLP M PAKREAY ADITYGTNN Sbjct: 121 LTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNN 180 Query: 181 EFGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSELYIKMN 240 E+GFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSE+Y ++N Sbjct: 181 EYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVN 240 Query: 241 KVIPHLVPQEKEDSDTFQGEGDYSVDEKTRQVNITERGLVKIEGLLAEAGMMKEGESLYS 300 K+IPHL+ QEKEDS+TFQGEG +SVDEK+RQVN+TERGLV IE LL + G+M EGESLYS Sbjct: 241 KIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYS 300 Query: 301 PANIMLMHHVTAALRAHALFTKDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAK 360 PANIMLMHHVTAALRAHALFT+DVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAK Sbjct: 301 PANIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAK 360 Query: 361 EGVKIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFNSIYRLETIVIPTNRPMVR 420 EGV+IQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEF+SIY+L+T+V+PTNRPM+R Sbjct: 361 EGVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIR 420 Query: 421 KDLPDLVYMNEKGKFAAIIEDIRERTKNGQPVLVGTISIEKSEEISQALTKANIHHNVLN 480 KDLPDLVYM E K AIIEDI+ERT GQPVLVGTISIEKSE +S LTKA I HNVLN Sbjct: 421 KDLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLN 480 Query: 481 AKFHAMEADIIANAGLPSAVTIATNMAGRGTDIVLGGSWQTEVAKLENPTEEQIEEIKAQ 540 AKFHA EA I+A AG P+AVTIATNMAGRGTDIVLGGSWQ EVA LENPT EQIE+IKA Sbjct: 481 AKFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKAD 540 Query: 541 WQKRHDAVLASGGLHIIGTERHESRRIDNQLRGRAGRQGDEGSSRFYLSMEDSLMRIFAS 600 WQ RHDAVL +GGLHIIGTERHESRRIDNQLRGR+GRQGD GSSRFYLSMED+LMRIFAS Sbjct: 541 WQVRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFAS 600 Query: 601 DKVSGMMRKLGMNETEAIEHPWVTKAIANAQRKVENRNFDIRKQLLEYDDVANDQRRAIY 660 D+VSGMMRKLGM EAIEHPWVTKAIANAQRKVE+RNFDIRKQLLEYDDVANDQRRAIY Sbjct: 601 DRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIY 660 Query: 661 TQRNELLDVADVSETIDSIRQDVFTSMIDNYIPPQSLEEMWDIEGLTACLQNDFDLNLPI 720 +QRNELLDV+DVSETI+SIR+DVF + ID YIPPQSLEEMWDI GL L+NDFDL+LPI Sbjct: 661 SQRNELLDVSDVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPI 720 Query: 721 KEWLDKEPELHEETLRERILEKSIEVYKAKEEIVSAEMMRNFEKGVMLQTLDSLWKEHLA 780 EWLDKEPELHEETLRERIL +SIEVY+ KEE+V AEMMR+FEKGVMLQTLDSLWKEHLA Sbjct: 721 AEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLA 780 Query: 781 AMDYLRQGIHLRGYAQKDPKQEYKRESFAMFANMLESLKYEVISTLSKVQVRLPEEVEEL 840 AMDYLRQGIHLRGYAQKDPKQEYKRESF+MFA MLESLKYEVISTLSKVQVR+PEEVEEL Sbjct: 781 AMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEEL 840 Query: 841 ERRRREEAERLAKQQQLSHEVTKESQMSAVDGQVASGKKVGRNEPCPCGSGKKYKHCHGK 900 E++RR EAERLA+ QQLSH+ + +A+ Q KVGRN+PCPCGSGKKYK CHG+ Sbjct: 841 EQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGER-KVGRNDPCPCGSGKKYKQCHGR 899 Query: 901 L 901 L Sbjct: 900 L 900
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 29.8 bits (67), Expect = 0.020 Identities = 17/59 (28%), Positives = 25/59 (42%), Gaps = 15/59 (25%) Query: 322 EITLVTNKQNQQNAME--NRYQQMQNSMSSFSTVEESKPAAKAVNEQSTQANKEPDYLD 378 +ITL NK QN +Y ++ K + +A NEQ Q +E +YL Sbjct: 370 KITLDENKTPSQNVQSYYKKYNKL-------------KKSEEAANEQLLQNEEELNYLY 415
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 52.8 bits (127), Expect = 1e-09 Identities = 50/223 (22%), Positives = 79/223 (35%), Gaps = 30/223 (13%) Query: 171 IVKAVERCGLKVDQLIFAGLASSFAVLTEDERELGVCVVDMGGGTMDIAIYTGGALRHTR 230 I ++ + G + LI +A++ G VVD+GGGT ++A+ + + ++ Sbjct: 126 IRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNGVVYSS 185 Query: 231 VIPYAGNVVTSDI------AYAFGTPPNDAEAIKVRHGCALGSLVGKDENVEVPSVGGRP 284 + G+ I Y AE IK G A + V V GR Sbjct: 186 SVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAY-----PGDEVREIEVRGRN 240 Query: 285 -----PRSLQRQTLAEVIEPRYTELLNLVNEEILSVQEQLRQQGIKHHLAAGIVLTGGAA 339 PR E++E E L + ++ EQ + G+VLTGG A Sbjct: 241 LAEGVPRGF-TLNSNEILEA-LQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGA 298 Query: 340 QIDGLVECAQRVFHTQVRIGKPLNITGLTDYAQDPFYSTAVGL 382 + L G P+ + A+DP A G Sbjct: 299 LLRNLDRLLMEE------TGIPVVV------AEDPLTCVARGG 329
>TETREPRESSOR#Tetracycline repressor protein signature. Length = 218 Score = 317 bits (813), Expect = e-113 Identities = 125/203 (61%), Positives = 156/203 (76%), Gaps = 2/203 (0%) Query: 1 MAKLDKEQVIDNALILLNEVGMEGLTTRKLAQKLGVEQPTLYWHVKNKRALLDALAETIL 60 MA+L++E VID AL LLNE G++GLTTRKLAQKLG+EQPTLYWHVKNKRALLDALA IL Sbjct: 1 MARLNRESVIDAALELLNETGIDGLTTRKLAQKLGIEQPTLYWHVKNKRALLDALAVEIL 60 Query: 61 QKHHHHVLPLANESWQDFLRNNAISFRQALLMYRDGGKIHAGTRPSANQFETSEQQLQFL 120 +HH + LP A ESWQ FLRNNA+SFR+ALL YRDG K+H GTRP Q++T E QL+F+ Sbjct: 61 ARHHDYSLPAAGESWQSFLRNNAMSFRRALLRYRDGAKVHLGTRPDEKQYDTVETQLRFM 120 Query: 121 CDAGFTLTQAVYALSSIAHFTLGSVLETQEHQESQKEREKVPKIEINYPPLLTQAIDIMD 180 + GF+L +YA+S+++HFTLG+VLE QEH + +R P + N PPLL +A+ IMD Sbjct: 121 TENGFSLRDGLYAISAVSHFTLGAVLEQQEHTAALTDRPAAP--DENLPPLLREALQIMD 178 Query: 181 SDNGEAAFLFVLDVMISGLETVL 203 SD+GE AFL L+ +I G E L Sbjct: 179 SDDGEQAFLHGLESLIRGFEVQL 201
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 429 bits (1104), Expect = e-152 Identities = 183/383 (47%), Positives = 249/383 (65%), Gaps = 3/383 (0%) Query: 2 NKLIIIILLVTVLDAIGIGLIMPVLPTLLNEFVSENRLANHYGILLALYATMQVIFAPIL 61 N+ +I+IL LDA+GIGLIMPVLP LL + V N + HYGILLALYA MQ AP+L Sbjct: 4 NRPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVL 63 Query: 62 GKLSDKYGRKPILLFSLLGAALDYLLMACSTSLWMLYIGRIIAGITGATGAVCASAMTDV 121 G LSD++GR+P+LL SL GAA+DY +MA + LW+LYIGRI+AGITGATGAV + + D+ Sbjct: 64 GALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADI 123 Query: 122 THSHERTRYFGFLGGAFGVGLIIGPMLGGLLGEISAHTPFIFAAISHSLLFIFSLLCFQE 181 T ER R+FGF+ FG G++ GP+LGGL+G S H PF AA + L F+ E Sbjct: 124 TDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPE 183 Query: 182 TQTTKISTE-ISALNQETAPHSATGFIKKSLCFWLIAYFIIQLIGQIPATIWVLFTQVRF 240 + + ALN + A G + + +FI+QL+GQ+PA +WV+F + RF Sbjct: 184 SHKGERRPLRREALNPLASFRWARGM--TVVAALMAVFFIMQLVGQVPAALWVIFGEDRF 241 Query: 241 AWHTTEVGLSLAFLGVLHIFFQAVLAGKLAQKWGERNTVIISMSIDAFGCLLLAWISHVW 300 W T +G+SLA G+LH QA++ G +A + GER +++ M D G +LLA+ + W Sbjct: 242 HWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGW 301 Query: 301 VMLPALICLAAGGMGQPALQGYLSKSVDHHVQGQLQGTLVSLTNITGIVGPLLFSFIYSY 360 + P ++ LA+GG+G PALQ LS+ VD QGQLQG+L +LT++T IVGPLLF+ IY+ Sbjct: 302 MAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAA 361 Query: 361 SVEYWDGLLWFIGAMLYSGLLVA 383 S+ W+G W GA LY L A Sbjct: 362 SITTWNGWAWIAGAALYLLCLPA 384
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 27.9 bits (62), Expect = 0.025 Identities = 12/58 (20%), Positives = 22/58 (37%), Gaps = 6/58 (10%) Query: 33 IGDAD----HGLNMNRGFKKVAEKLPEFADK--DIGFILKNTGMTLLSNIGGASGPLF 84 +AD +G+N+ G KL E A K + + + G+ ++ G Sbjct: 79 TSEADLIFYNGINLETGGNAWFTKLVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKE 136
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 157 bits (399), Expect = 3e-44 Identities = 51/217 (23%), Positives = 109/217 (50%), Gaps = 3/217 (1%) Query: 264 GPAFIWHELELAPIENLSAPLDSTIQIEQFNQAIKDTLNDLKHYAEKANHTLGEQIGAIF 323 AFI E + IE S D + +IE+ A++ + +L+ ++ ++G IF Sbjct: 17 AKAFIHLEPNVD-IEKTSI-TDVSTEIEKLTAALEKSKEELRAIKDQTEASMGADKAEIF 74 Query: 324 NGHIMMLDDEELLTNVIDRIKTDNVSAQQSWTNEMKERIQLYRTLSDPYLRARELDLRDL 383 H+++LDD EL+ + +I+ + ++A+ + + ++ ++ + Y++ R D+RD+ Sbjct: 75 AAHLLVLDDPELVDGIKGKIENEQMNAEYALKEVSDMFVSMFESMDNEYMKERAADIRDV 134 Query: 384 RNQVLYHLQ-QKTPPKFTPSQPSILVAKELFPSTLIQFDATQLLAITLAEGDSCSHSAII 442 +VL HL +T T ++ ++++A++L PS Q + + G SHSAI+ Sbjct: 135 SKRVLGHLIGVETGSLATIAEETVIIAEDLTPSDTAQLNKQFVKGFATDIGGRTSHSAIM 194 Query: 443 ATQMGLPMLVHLGDGLLKIKEAQELTLDLKSSELIIG 479 + + +P +V + KI+ + +D +I+ Sbjct: 195 SRSLEIPAVVGTKEVTEKIQHGDMVIVDGIEGIVIVN 231
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 268 bits (686), Expect = 2e-87 Identities = 118/477 (24%), Positives = 194/477 (40%), Gaps = 68/477 (14%) Query: 11 VLLIDDDEDILESYRHLLNLAGMVARVTDSPEKALSLLTPEYEGAVVLDIYMPAMNGMEV 70 +L+ DDD I L+ AG R+T + + VV D+ MP N ++ Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 71 LARIQQIDPRIPVIMITGHGDIPLAVEAVKKGAYDFIEKPINPPLFLELVAKAHKERKSL 130 L RI++ P +PV++++ A++A +KGAYD++ KP + + ++ +A E K Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRR 125 Query: 131 LSLRKTMITTTQERLVGDSAQITAIRQQVQQIADIDKDLMIEGEMGTGRHLLAQLLHELS 190 S + LVG SA + I + + ++ D LMI GE GTG+ L+A+ LH+ Sbjct: 126 PSKLEDDSQDGMP-LVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYG 184 Query: 191 PHSDKAVTTVDCQNLVD------------------IKPLIAQIEQEEVGTLILRSPYDLP 232 + ++ + + EQ E GTL L D+P Sbjct: 185 KRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMP 244 Query: 233 SGAQRWLSAYLLD--MERQGKRQ-----FRTIAILENNTQQLVTEGRLIPEFYYYFSQIT 285 AQ L L G R R +A + +Q + +G + YY + + Sbjct: 245 MDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVP 304 Query: 286 FSLPPLSARRPDIIPLFRAFLRQSAQRLGIAVPKIDRNYLDILKRYDWPGNIRELRNVAE 345 LPPL R DI L R F++Q+ + G+ V + D+ L+++K + WPGN+REL N+ Sbjct: 305 LRLPPLRDRAEDIPDLVRHFVQQAE-KEGLDVKRFDQEALELMKAHPWPGNVRELENLVR 363 Query: 346 LYAV-----GIVKMVDSEQHRAIIP----------------------------------- 365 I + + + R+ IP Sbjct: 364 RLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDAL 423 Query: 366 -PEGPLDNLVDDYERRLIEDALYLFAGRVSDVADYLGIPRKKLYLRMKKHELDKESY 421 P G D ++ + E LI AL G AD LG+ R L ++++ + Sbjct: 424 PPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVSVYRS 480
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 34.1 bits (78), Expect = 0.001 Identities = 28/126 (22%), Positives = 51/126 (40%), Gaps = 7/126 (5%) Query: 63 VTTAELGLMGSAFFFTYAFGKFSNGFLSDYANIGRFMSISLIASSFVCIFMGMSTASLFF 122 A + +AF T++ G G LSD I R + +I + F + +G S F Sbjct: 46 KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSV-IGFVGHSFFS 104 Query: 123 ILLWGINGWFQSVGSAP----SCVSIFQWFSPKQRGTVYSIWGGSRNIGEAITWILTATI 178 +L+ + Q G+A V + ++ + RG + + G +GE + + I Sbjct: 105 LLIMA--RFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMI 162 Query: 179 VSFFGW 184 + W Sbjct: 163 AHYIHW 168
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.0 bits (67), Expect = 0.011 Identities = 25/142 (17%), Positives = 51/142 (35%), Gaps = 12/142 (8%) Query: 47 SEALSQLGQRLQAIEMKMADSVTDDRMNAQLDVLRQGLTTLKQDVASQ----RDTLRTVT 102 +E Q + ++ E ++ +R A+ T +VA ++T T T Sbjct: 1041 AENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTET 1100 Query: 103 AQLAVAGKPDEQIAVLSDGLE--KRLAQLETRQAQWALALHQLQEQRQPEQKTVNPPVVR 160 + A K ++ E K +Q+ +Q Q Q + R+ + P V Sbjct: 1101 KETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPAREND------PTVN 1154 Query: 161 AKPATPETSRLGASVRPSRTVP 182 K +T+ + +P++ Sbjct: 1155 IKEPQSQTNTTADTEQPAKETS 1176
>SOPEPROTEIN#Salmonella type III secretion SopE effector protein signature. Length = 239 Score = 28.2 bits (62), Expect = 0.021 Identities = 12/40 (30%), Positives = 21/40 (52%) Query: 166 EYTPSAPDAGMSGASSVSVVTPLSAGSTPLPVPPVLNTST 205 E +A +AG+ G + V TP AG+ P P + + ++ Sbjct: 142 EIGEAAKNAGLPGTTKNDVFTPSGAGANPFITPLISSANS 181
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 45.4 bits (107), Expect = 2e-06 Identities = 18/65 (27%), Positives = 37/65 (56%) Query: 9 NIKELCSKQINIDKNKFSDKDNLIKLGLDSIGFMQCLYIFQKNGYAITLKDLYLNPTIKG 68 NI++ ++ + +D+++L+ GLDS+ M + +++ G +T +L PTI+ Sbjct: 234 NIRKQIAELLQETPEDITDQEDLLDRGLDSVRIMTLVEQWRREGAEVTFVELAERPTIEE 293 Query: 69 WYKIL 73 W K+L Sbjct: 294 WQKLL 298
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 47.7 bits (113), Expect = 3e-07 Identities = 49/198 (24%), Positives = 73/198 (36%), Gaps = 31/198 (15%) Query: 1464 ITGGFGGLGRITASWLVRQGAKRIAILAPRADSSALDWMNNLQKSNQLEIKW---LTCDC 1520 ITG G+G A L QGA A+ + + + S + E + D Sbjct: 13 ITGAAQGIGEAVARTLASQGAHIAAV------DYNPEKLEKVVSSLKAEARHAEAFPADV 66 Query: 1521 RDNAKCHAALTQLENE-GGIEGLIHSAGILDDALMTQLTPKRMSDVFSVKAI-------- 1571 RD+A ++E E G I+ L++ AG+L L+ L+ + FSV + Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 1572 SAKQFCDALEKTDASYLILYSSAAAT-------IGSEGQAAHSLACGYLDGLAEYARR-N 1623 +K D + S + + S+ A S AA LAEY R N Sbjct: 127 VSKYMMD---RRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 1624 I--KGLTVISIAWGAWQS 1639 I G T + W W Sbjct: 184 IVSPGSTETDMQWSLWAD 201
>cloacin#Cloacin signature. Length = 551 Score = 30.5 bits (68), Expect = 0.013 Identities = 17/48 (35%), Positives = 21/48 (43%), Gaps = 5/48 (10%) Query: 348 SGYSGSGGYSSSSYSSSSSS-----SSSSSSSSSGGGGGSSGGGGASG 390 +G GG S S SS ++ S S G G G+ GG G SG Sbjct: 25 TGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSG 72
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 49.7 bits (118), Expect = 4e-08 Identities = 49/319 (15%), Positives = 91/319 (28%), Gaps = 20/319 (6%) Query: 293 REENRMREVEVAQQNRTRAVAIEQERVNRARELEIVAREREVELQRIEKEKALEEERKNI 352 E R + V+ + + V E +AR E + E Sbjct: 984 EVEKRNQTVDTTNITTPNNIQADVPSVPSNNEE--IARVDEAPVPPPAPATPSETTETVA 1041 Query: 353 SNVIRERVAVEKTVAQEEERIKEVREVSEAERMR------QVTVINAQAEAEESLVRQVK 406 N +E VEK E + REV++ + V + +E +E+ + K Sbjct: 1042 ENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETK 1101 Query: 407 KAEADESSAKHKAEEISTMAKAELEASVK----QAEAKKRLAEGIEAEHAALGLAEARVR 462 + E K K E T ++ + V Q+E + AE + + E + + Sbjct: 1102 ETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQ 1161 Query: 463 QATAEAEEKEGLVQANITAEQLLAQARGLKEKGLSEAQVMEAKAQAQQQQGFAEAKILEE 522 T E+ ++ + + + E A Q + + Sbjct: 1162 TNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKN 1221 Query: 523 KLAAQARGEEQQANAKEKLGLADAKILEEKLAAQARGEGQLGSAQAEVIRQRLKAEADGL 582 + R A + A + + A + R KA+ L Sbjct: 1222 RHRRSVRSVPHNVE--------PATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVAL 1273 Query: 583 TDKFKSMDHLSDTARAHEE 601 H+S +E Sbjct: 1274 NVGKAVSQHISQLEMNNEG 1292 Score = 49.3 bits (117), Expect = 5e-08 Identities = 33/235 (14%), Positives = 80/235 (34%), Gaps = 17/235 (7%) Query: 215 IETNQKERDQELAIQKKNVETREASLALERQQADAEARQQREIDNIRARESSETLRVQEE 274 +E N+++ + A ++ + ++++ Q + A+ E + E+ ET V++E Sbjct: 1051 VEKNEQDATETTAQNREVAKEAKSNVKANTQTNEV-AQSGSETKETQTTETKETATVEKE 1109 Query: 275 ERLKAEQARIQ----TQQEIEIREENRMREVEVAQQNRTRAVAI-----------EQERV 319 E+ K E + Q ++ ++E A+ R + + Sbjct: 1110 EKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTE 1169 Query: 320 NRARELEIVAREREVELQRIEKEKALEEERKNISNVIRERVAVEKTVAQEEER-IKEVRE 378 A+E + E + ++ E +N + + ++ + + R + VR Sbjct: 1170 QPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRS 1229 Query: 379 VSEAERMRQVTVINAQAEAEESLVRQVKKAEADESSAKHKAEEISTMAKAELEAS 433 V + + A L A ++ AK + ++ S Sbjct: 1230 VPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHIS 1284 Score = 40.8 bits (95), Expect = 2e-05 Identities = 43/286 (15%), Positives = 80/286 (27%), Gaps = 24/286 (8%) Query: 199 DSEGIRKITEITAIHNIETNQKERDQELAIQKKNVETREASLALERQQADAEARQQREID 258 ++E I ++ E E + +A K ++ Q A Q RE+ Sbjct: 1013 NNEEIARVDEAPVPPPAPATPSETTETVAENSKQES---KTVEKNEQDATETTAQNREVA 1069 Query: 259 NIRARESSETLRVQEEERLKAEQARIQTQQ--EIEIREENRMREVEVAQQNRTRAVAIEQ 316 + E + +E QT + E E+ +VE + Sbjct: 1070 KEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKT---------- 1119 Query: 317 ERVNRARELEIVAREREVELQRIEKEKALEEERKNISNV-IRERVAVEKTVAQEEERIKE 375 ++ ++ + Q + E R+N V I+E + T A E+ KE Sbjct: 1120 -----QEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKE 1174 Query: 376 VREVSEAERMRQVTVINAQAEAEESLVRQVKKAEADESSAKHKAEEISTMAKAELEASVK 435 E TV + E + +S + + + + Sbjct: 1175 TSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPK--NRHRRSVRSVPH 1232 Query: 436 QAEAKKRLAEGIEAEHAALGLAEARVRQATAEAEEKEGLVQANITA 481 E + A L ++A K V N+ Sbjct: 1233 NVEPATTSSNDRSTV-ALCDLTSTNTNAVLSDARAKAQFVALNVGK 1277
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 35.4 bits (81), Expect = 0.002 Identities = 54/348 (15%), Positives = 111/348 (31%), Gaps = 36/348 (10%) Query: 514 EKVESIRQQSAKSMQEAINRQKSLLSLTLPDSWTDIQQFVDSLNSLNTHHGHLISLREFR 573 EK + + K+ QEA R+K + + L E Sbjct: 137 EKARKEAEAAEKAFQEAEQRRKEIEREK-------------------AETERQLKLAEAE 177 Query: 574 YMDLTQLNKMETEITEAQQRVSQATAQFLASDKALQPFKTQLTTFEQQIEKAQNSAQLDV 633 L L++ + AQ+++S A ++ + D ++ ++L++ + + L Sbjct: 178 EKRLAALSEEAKAVEIAQKKLSAAQSEVVKMDGEIKTLNSRLSSSIHARDAEMKT--LAG 235 Query: 634 PMNEMAQMS---EDLDMLSNLMASLTFEDVTQQTQIIDAISQIYAQLNQSRARLQQKRKS 690 NE+AQ S ++LD L ++ + + + ++ A + + Q Sbjct: 236 KRNELAQASAKYKELDELVKKLSPRANDPLQNRPFFEATRRRVGAGKIREEKQKQVTASE 295 Query: 691 QSSVETVAQFGAQFRLFSQGITNALSLATDPERCEEQLSRLLVQLEELESQFSQHDEFLD 750 A + SQ N + EE L + Q L SQ + Sbjct: 296 TRINRINADITQIQKAISQVSNNRNAGIARVHEAEENLKK--AQNNLLNSQIKDAVDATV 353 Query: 751 DILSK-REELLETFEAHKQSLLDDRQ----RRSQSLLTAANRLLENLQRRTTRLQSQDEL 805 E+ E + Q L D + L A + + L ++ ++ Sbjct: 354 SFYQTLTEKYGEKYSKMAQELADKSKGKKIGNVNEALAAFEKYKDVLNKKFSKADRDAIF 413 Query: 806 NAFFASDPLALKTREIIEKLREINDNVKADDIDARLKSSRDQAIRILR 853 NA ++K + + L + +K + ++I Sbjct: 414 NAL-----ASVKYDDWAKHLDQFAKYLKITGHVSFGYDVVSDILKIKD 456
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.8 bits (93), Expect = 2e-05 Identities = 61/316 (19%), Positives = 116/316 (36%), Gaps = 27/316 (8%) Query: 30 GYVLVIIGVALEQLTPILQLDTRWIGLLGAATLAGLFIGTSLFGYICDKVGRRKMFLVDI 89 G ++ ++ L L + + G+L A F + G + D+ GRR + LV + Sbjct: 22 GLIMPVLPGLLRDLVHSNDVTAHY-GILLALYALMQFACAPVLGALSDRFGRRPVLLVSL 80 Query: 90 VAIAVISIATMFVSTPIGLLVMRFLIGIVIGADYPIATSMITEFSNKKQRAFAVGFIAAM 149 A A + A M + + +L + ++ + GA +A + I + ++ +RA GF++A Sbjct: 81 -AGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGFMSAC 139 Query: 150 WYIGATCANLVGYLLYDVQDGWRWMLGSAFIPCVIILIGRFDLPESPLWLIRQGRIKECN 209 + G ++G L+ + +A + G F LPES +G + Sbjct: 140 FGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLT-GCFLLPES-----HKGERRPLR 193 Query: 210 EMMIKLFGEPVVFEAEDAKTTRFIELFNKRHFSFVLFVA-VIWTCQVIPMFAIYTFGPQI 268 + F + ++ V ++ +P FG Sbjct: 194 REALNPL-------------ASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDR 240 Query: 269 VGLLGWDTGRSAALGNVVISLFFMLGCIPAMFWLNQTGRRPLLIGSFAMMT---LALFTL 325 G S A ++ SL + P L + RR L++G A T L F Sbjct: 241 FHWDATTIGISLAAFGILHSLAQAMITGPVAARLGE--RRALMLGMIADGTGYILLAFAT 298 Query: 326 GIFPNLPILFVILAFA 341 + PI+ ++ + Sbjct: 299 RGWMAFPIMVLLASGG 314 Score = 29.8 bits (67), Expect = 0.020 Identities = 23/124 (18%), Positives = 53/124 (42%), Gaps = 7/124 (5%) Query: 71 LFGYICDKVGRRKMFLVDIVAIAVISIATMF-VSTPIGLLVMRFLIGIVIGADYPIATSM 129 + G + ++G R+ ++ ++A I F + +M L IG P +M Sbjct: 266 ITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGM--PALQAM 323 Query: 130 ITEFSNKKQRAFAVGFIAAMWYIGATCANLVGYLLYDVQ----DGWRWMLGSAFIPCVII 185 ++ +++++ G +AA+ + + L+ +Y +GW W+ G+A + Sbjct: 324 LSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASITTWNGWAWIAGAALYLLCLP 383 Query: 186 LIGR 189 + R Sbjct: 384 ALRR 387
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 128 bits (322), Expect = 2e-38 Identities = 78/230 (33%), Positives = 128/230 (55%), Gaps = 9/230 (3%) Query: 19 SAPHALAEETAKVPTLNSAFKTQDEQNAYALGASMGRYMEAALTEQKNIGINLDSKQLLA 78 +A LA TA T ++ T ++ +Y++GA +G+ KN GI+++ L Sbjct: 8 AAIMGLAMSTAMAATDATSLTTDKDKLSYSIGADLGKNF-------KNQGIDINPDVLAK 60 Query: 79 GVQDAFN-NKSKLSDAEIELTLAAFEDQVRTVATAKMEKEAAENKAAGDKFRTEFAAEKG 137 G+QD + + L++ +++ L+ F+ + +A+ K+A ENKA GD F + ++ G Sbjct: 61 GMQDGMSGAQLILTEEQMKDVLSKFQKDLMAKRSAEFNKKAEENKAKGDAFLSANKSKPG 120 Query: 138 VVKTKSGLLYLVENPGKGKTPTDADRVTVNYKGMLIDGKQFDSSYDRKEPLTISLKSVIP 197 +V SGL Y + + G G P +D VTV Y G LIDG FDS+ +P T + VIP Sbjct: 121 IVVLPSGLQYKIIDAGTGAKPGKSDTVTVEYTGTLIDGTVFDSTEKAGKPATFQVSQVIP 180 Query: 198 GWTEGMKYIKEGGKIKLVIPPELGYGQRATSG-IPANSTLVFEVELLSVE 246 GWTE ++ + G ++ +P +L YG R+ G I N TL+F++ L+SV+ Sbjct: 181 GWTEALQLMPAGSTWEVFVPADLAYGPRSVGGPIGPNETLIFKIHLISVK 230
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 24.7 bits (54), Expect = 0.032 Identities = 12/61 (19%), Positives = 25/61 (40%), Gaps = 7/61 (11%) Query: 6 IEELLIQLESKIAFQDATIEELNQVVTQQQIEISRFKEALKIVTERLKSSQSSMLARPED 65 I + I LE + + +I +++ EI + AL+ E L++ + A Sbjct: 16 IAKAFIHLEPNVDIEKTSITDVST-------EIEKLTAALEKSKEELRAIKDQTEASMGA 68 Query: 66 E 66 + Sbjct: 69 D 69
>cloacin#Cloacin signature. Length = 551 Score = 29.3 bits (65), Expect = 0.012 Identities = 15/45 (33%), Positives = 15/45 (33%) Query: 164 GHGHGEEGGCCGGGHGHGHDHDHGEEGGCCGGGHGKGGHGHGHGG 208 G G E GGG G G G G GG GG G Sbjct: 36 GSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGN 80
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.040 Identities = 14/55 (25%), Positives = 23/55 (41%), Gaps = 5/55 (9%) Query: 1 MIVFSSLQIRRGVRVLLDNASATI-NPGQK----IGLVGKNGCGKTTLLSLLKGD 50 ++ + +L A + PG K + L G G GK+TL++ L G Sbjct: 565 YKPRRLRYLQLVGKYILMGHVARVMEPGCKFDYSVVLEGTGGIGKSTLINTLVGL 619
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 30.4 bits (68), Expect = 0.019 Identities = 37/288 (12%), Positives = 87/288 (30%), Gaps = 4/288 (1%) Query: 253 LINGIQYMRSELSLIVNAIRGTSHHIYNGVQELSAGNNDLSSRTQEQASALEETASSMEQ 312 + + + L L + + + + + EL+ ++ + ++ +L E AS +++ Sbjct: 58 RADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQE 117 Query: 313 LTAT----VKNNTESAREVSHLINQTSNIASKGGDVTHRMVKTMNDIAQSSQKIGEITTV 368 L A K + + + + ++ + R + + + Sbjct: 118 LEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAK 177 Query: 369 INSIAFQTNILSLNAAVEAARAGEQGRGFSVVATEVRELAQRSAEAAKEIKELIDASINR 428 I ++ + L A + + +++ L A A +L A Sbjct: 178 IKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGA 237 Query: 429 VKQGNQLVEQVSTSMDEILTSVKHVESSMTEILSASEEQTRGISQVSLAVTEMDKATQQN 488 + ++ T E + A T +++ E + Sbjct: 238 MNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEK 297 Query: 489 AAMVEQSSAVASLLTEEAGDLEQIVEQFKTAESLFSKKSTLTKPVEKS 536 A + QS + + DL+ E K E+ K K E S Sbjct: 298 ADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEAS 345
>PF06580#Sensor histidine kinase Length = 349 Score = 30.6 bits (69), Expect = 0.013 Identities = 18/105 (17%), Positives = 36/105 (34%), Gaps = 28/105 (26%) Query: 357 IVRNALRY------SHSRIEVAFTEQNQGITIIVDDDGPGVSPEDREHIFRPFYRTDEAR 410 +V N +++ +I + T+ N +T+ V++ G +E Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE------------- 309 Query: 411 DRESGGTGLGLAIVETAISQHRG---HVKADDSPLGGLRVEIWLP 452 TG GL V + G +K + G + + +P Sbjct: 310 -----STGTGLQNVRERLQMLYGTEAQIKLSEKQ-GKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 92.6 bits (230), Expect = 7e-24 Identities = 33/117 (28%), Positives = 64/117 (54%), Gaps = 2/117 (1%) Query: 3 KILLVDDDRELTSLLKELLEMEGFNVVLATDGEQALKLL-DASIDLLLLDIMMPRKNGIE 61 IL+ DDD + ++L + L G++V + ++ + + DL++ D++MP +N + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 TLKELRQ-NFQTPVIMLTARGSDLDRVLGLELGADDYLPKPFNDRELVARIRAILRR 117 L +++ PV++++A+ + + + E GA DYLPKPF+ EL+ I L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 123 bits (309), Expect = 3e-36 Identities = 71/255 (27%), Positives = 115/255 (45%), Gaps = 16/255 (6%) Query: 4 LTGKIALVSGGAKGIGKGIVSALKNSGAQVIIADIDD-----VAGNATKEALGVDFMHLD 58 + GKIA ++G A+GIG+ + L + GA + D + V + EA + D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 59 VTSQAACEQVVNDIVKQYGKLDILCSNTGIFPQATIKEMSEADWDKMHTVNLKGMFFLVK 118 V AA +++ I ++ G +DIL + G+ I +S+ +W+ +VN G+F + Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 119 AALAVMEKQQYGRVIITSSITGAITGYPGWSHYGASKAGQLGFMRSAALEYARHGITINA 178 + M ++ G ++ S A + Y +SKA + F + LE A + I N Sbjct: 126 SVSKYMMDRRSGSIVTVGS-NPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184 Query: 179 VMPGNILTE----------GLQAQGETYLNQMKASIPTHTLGEPEDIGYAAAFFASNEAK 228 V PG+ T+ G + + L K IP L +P DI A F S +A Sbjct: 185 VSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAG 244 Query: 229 YITGQTIIVDGGQIL 243 +IT + VDGG L Sbjct: 245 HITMHNLCVDGGATL 259
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 30.4 bits (68), Expect = 0.009 Identities = 12/42 (28%), Positives = 21/42 (50%) Query: 275 QLINPLEYYYPAKISPVALKTLMDAQERCVQVSVNKLKELRK 316 Q++ P YY ++P+AL D + ++ N+ EL K Sbjct: 432 QILAPNNYYPSKNLAPIALNAQDDFSSTPITMNYNQFLELEK 473
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 65.6 bits (160), Expect = 1e-14 Identities = 29/114 (25%), Positives = 48/114 (42%), Gaps = 5/114 (4%) Query: 3 ILIVDDEPLARENLRCLLEEEKDIHIIGECSNAIEAIGEIHRKKPDVVFLDIQMPRITGL 62 IL+ DD+ R L L + + SNA I D+V D+ MP Sbjct: 6 ILVADDDAAIRTVLNQALSRAG--YDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 63 EMV-SMLDPEHRPYIVFLTAFE--EYAIQAFEEHAFDYLLKPLEQERLAKTLSR 113 +++ + ++ ++A AI+A E+ A+DYL KP + L + R Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>PF06580#Sensor histidine kinase Length = 349 Score = 199 bits (507), Expect = 7e-61 Identities = 60/201 (29%), Positives = 111/201 (55%), Gaps = 7/201 (3%) Query: 353 AQILAGQYERNKQSLLESEIKLLHAQVNPHFLFNALNTLQAVIRRDSDQAKQLVQFLSAF 412 A+I + Q E+++ L AQ+NPHF+FNALN ++A+I D +A++++ LS Sbjct: 147 AEIDQWKMASMAQ---EAQLMALKAQINPHFMFNALNNIRALILEDPTKAREMLTSLSEL 203 Query: 413 FRKNLKR-PEAIVTLSDEIEHVTAYLQIEKARFQESLQIDIQIPEHLATARLPAFSLQPM 471 R +L+ V+L+DE+ V +YLQ+ +F++ LQ + QI + ++P +Q + Sbjct: 204 MRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTL 263 Query: 472 VENAIKHGTSQLLGIGKITIRAHQEDHLIVIEISDNAGL-YHSQGASHQLGLGMRLVDKR 530 VEN IKHG +QL GKI ++ +++ + +E+ + L + S G G++ V +R Sbjct: 264 VENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKEST--GTGLQNVRER 321 Query: 531 IKLRYGDLYGVLVECQPDNYT 551 +++ YG + + + Sbjct: 322 LQMLYGTEAQIKLSEKQGKVN 342
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 52.5 bits (126), Expect = 8e-10 Identities = 37/267 (13%), Positives = 86/267 (32%), Gaps = 33/267 (12%) Query: 75 LNAQVAALEAAKAQAQAQLDLSIHGTREESIRNLQAILSQAQAQATNATKDYQRLSAVAN 134 + Q + + K Q + LD + + A +++ + + S++ + Sbjct: 191 IKEQFSTWQNQKYQKELNLD-----KKRAERLTVLARINRYENLSRVEKSRLDDFSSLLH 245 Query: 135 KGYVSAN--------------ELDSARSRRDVAVQQAKAAQAELDEAKNGDRIELREKYR 180 K ++ + EL +S+ + + +A+ E + E+ +K R Sbjct: 246 KQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLR 305 Query: 181 AA---LQQAEQQLIELKVQQQDLQVKAPVDGEVGPIPA-EVGELFNANSPLATLIRLPEA 236 + +L + + +QQ ++APV +V + G + L ++ + Sbjct: 306 QTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDT 365 Query: 237 YFVY-NLREDILADIRKGDRITITVPALGNKE---VEAEVRYIAP--MGDYATKRATRAT 290 V ++ + I G I V A + +V+ I + D Sbjct: 366 LEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVI 425 Query: 291 GDFDLKTFEVRLYPTAQIEGLRPGMSA 317 + + L GM+ Sbjct: 426 ISIEENCLSTGN----KNIPLSSGMAV 448 Score = 46.4 bits (110), Expect = 8e-08 Identities = 28/208 (13%), Positives = 66/208 (31%), Gaps = 17/208 (8%) Query: 4 RAIYLILLMLILIALAVLFRAH-NQYLLLQGEV--DAPEVIVASKAKGRVIERHIERGDD 60 R + ++ ++IA + G++ + V E ++ G+ Sbjct: 58 RLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGES 117 Query: 61 VKAGQLMITLDSPELNAQVAALEAAKAQA-------QAQLDLSIHGTREESIRNLQAILS 113 V+ G +++ L + A +++ QA Q E + Sbjct: 118 VRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQ 177 Query: 114 QAQAQATNATKDY--QRLSAVANKGYVSANELDSARSRRDVAVQ--QAKAAQAELDEAKN 169 + ++ S N+ Y LD R+ R + + +++++ Sbjct: 178 NVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRL 237 Query: 170 GDRIELREK---YRAALQQAEQQLIELK 194 D L K + A+ + E + +E Sbjct: 238 DDFSSLLHKQAIAKHAVLEQENKYVEAV 265
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 28.7 bits (64), Expect = 0.038 Identities = 15/62 (24%), Positives = 30/62 (48%) Query: 264 LAVLGLGKLITECLRSVEMIYLTLAFVTTPVFYISGTIWPLQAMPDWVLAISSALPSTWA 323 LA LG ++T S + V TP+ ++SG ++P+ +P + LP + + Sbjct: 159 LAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQTAARFLPLSHS 218 Query: 324 VN 325 ++ Sbjct: 219 ID 220
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 872 bits (2254), Expect = 0.0 Identities = 454/860 (52%), Positives = 623/860 (72%), Gaps = 21/860 (2%) Query: 20 LFIFILALLFSVDSKSEEEFYYNPYFLSDNPESVADLSSFEKGLEVPEGNYLVDIYLNDI 79 + +F+ + S E Y+NP FL+D+P++VADLS FE G E+P G Y VDIYLN+ Sbjct: 28 VRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNG 87 Query: 80 FLKTQYINFIE--NKGQLSPCITKAELKSWNVNLNLITDEQNKDKNNVEQKNELDEHCQS 137 ++ T+ + F ++ + PC+T+A+L S +N ++ D+ C Sbjct: 88 YMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLA----------DDACVP 137 Query: 138 LTSLISQATANFDVGSQKLNLTIPQVYLVNQSRGFIPPELWDDGIVAGFITYILNGSKTR 197 LTS+I ATA DVG Q+LNLTIPQ ++ N++RG+IPPELWD GI AG + Y +G+ + Sbjct: 138 LTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQ 197 Query: 198 NDGSPDTHFTHLNLQSGINLGPWRLRDNSIYSYDSINKSS-----WKHLNTYIERGINKL 252 N ++H+ +LNLQSG+N+G WRLRDN+ +SY+S + SS W+H+NT++ER I L Sbjct: 198 NRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPL 257 Query: 253 YSRLIIGDSYTQSEVFDSINFRGFQLSSDEVMLPDSQRGFAPIIRGVARTNAEVTIQQNG 312 SRL +GD YTQ ++FD INFRG QL+SD+ MLPDSQRGFAP+I G+AR A+VTI+QNG Sbjct: 258 RSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNG 317 Query: 313 YVIYRNSFPPGPFVIDDLYSTSNSGDLEVTITESDGSTQTFTVPYSSVPLLQREGHTKYS 372 Y IY ++ PPGPF I+D+Y+ NSGDL+VTI E+DGSTQ FTVPYSSVPLLQREGHT+YS Sbjct: 318 YDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYS 377 Query: 373 VTVGSYRSGNDEQERPYFLQGSVIHGLPAGWTIYGGTQLSKNYQAASIGVGKNIGRFGAL 432 +T G YRSGN +QE+P F Q +++HGLPAGWTIYGGTQL+ Y+A + G+GKN+G GAL Sbjct: 378 ITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGAL 437 Query: 433 SFDITEARSILPDDSTHRGQSIRILYNKSINELGTRVQLAGYKYATSGFYTLAETTYKKM 492 S D+T+A S LPDDS H GQS+R LYNKS+NE GT +QL GY+Y+TSG++ A+TTY +M Sbjct: 438 SVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRM 497 Query: 493 RGNYIQTEDGVVEVSGLPQSYYDLIYNKRQRIQLNITQKIGDQSTLYIIGTNQRYWNSKK 552 G I+T+DGV++V YY+L YNKR ++QL +TQ++G STLY+ G++Q YW + Sbjct: 498 NGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSN 557 Query: 553 QDNQLQIGLNTIIKGINLGLNYSLSKTSWNDSKDQMLAFNTSIPFSNFMRSDNDSIWQNA 612 D Q Q GLNT + IN L+YSL+K +W +DQMLA N +IPFS+++RSD+ S W++A Sbjct: 558 VDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHA 617 Query: 613 SLSTNSSHNMKKRFNNTIGLNGTLLEDKNLSYNIQTGYS--HEEESDSTGYASLSYNGSY 670 S S + SH++ R N G+ GTLLED NLSY++QTGY+ + S STGYA+L+Y G Y Sbjct: 618 SASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGY 677 Query: 671 MNSNIGYNYTDTSHQINYGMSGSILAHSGGITLSQPIYQTAVLVKVPEVKNIKLENNSGI 730 N+NIGY+++D Q+ YG+SG +LAH+ G+TL QP+ T VLVK P K+ K+EN +G+ Sbjct: 678 GNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGV 737 Query: 731 TTDSNGYAVLPYISEYKENRIALDTNSFSNNIEIDNAVKSVVPTRGAISAITFEPSVGIK 790 TD GYAVLPY +EY+ENR+ALDTN+ ++N+++DNAV +VVPTRGAI F+ VGIK Sbjct: 738 RTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIK 797 Query: 791 AITTLTHKGKPVPFGAIV--DSGNNTGIVADEGKVYLTGLSPSGQLKVNWGSKKEQQCLV 848 + TLTH KP+PFGA+V +S ++GIVAD G+VYL+G+ +G+++V WG ++ C+ Sbjct: 798 LLMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCVA 857 Query: 849 NYTLPPQDPDKLYVEYSAEC 868 NY LPP+ +L + SAEC Sbjct: 858 NYQLPPESQQQLLTQLSAEC 877