>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 40.6 bits (95), Expect = 9e-06 Identities = 28/195 (14%), Positives = 71/195 (36%), Gaps = 19/195 (9%) Query: 27 QIELENQSRF-LAQQKEFEKEVKEKRVQYQSHFKMLEQKEEALKEQEREQKAKFDDAVKQ 85 +++L ++ F ++E + + Q+ + QKE L ++ E+ + Sbjct: 167 ELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRY 226 Query: 86 ASVLALQDERAKIIEEARKNAFLEQQKGLELLQKELDEKSKQVQELHQKEAEIERLKREN 145 ++ ++ R + + LE + + E EL ++++E+++ E Sbjct: 227 ENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQ-ENKYVEAV---NELRVYKSQLEQIESEI 282 Query: 146 NEAESRLKAENEKKLNEKLETEREKIEKALHEKNELKFKQQEEQLEMLRNELKNAQRKAE 205 A+ + + NE L+ R+ +L + + +A Sbjct: 283 LSAKEEYQLVTQLFKNEILDKLRQ---------TTDNIGLLTLELAKNEERQQASVIRAP 333 Query: 206 LSSQQFQGEVQELAI 220 +S +VQ+L + Sbjct: 334 VS-----VKVQQLKV 343
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 32.2 bits (73), Expect = 0.002 Identities = 12/33 (36%), Positives = 20/33 (60%) Query: 70 EPEVQILKDLKPDFIVVVAYGKILPKEVLSIAP 102 EP +++L ++KP F+V A P+ + IAP Sbjct: 86 EPNLELLTEMKPSFMVWSAGYGPSPEMLARIAP 118
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 29.9 bits (67), Expect = 0.024 Identities = 20/68 (29%), Positives = 35/68 (51%), Gaps = 3/68 (4%) Query: 196 YVAIGQKESTVAQVVRKLEEYGAMEYSVVINASASDSAAMQYLAPYSGVAMGEYFR-DHA 254 Y+ +G K T Q+ +L YG EY+V N + + A ++G+ G+Y D+ Sbjct: 56 YMRVGFKGET--QINDQLTGYGQWEYNVQANTTEGEGANSWTRLAFAGLKFGDYGSFDYG 113 Query: 255 RHALIIYD 262 R+ ++YD Sbjct: 114 RNYGVLYD 121
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 28.1 bits (62), Expect = 0.041 Identities = 18/130 (13%), Positives = 33/130 (25%), Gaps = 6/130 (4%) Query: 33 EAEKILLDLGKKNEQIIDLNLEDLPSDEKKDEKVVEKNATDKEGDFIDPKEQEESLENIF 92 A+ L+ K + LE E + ++ LE Sbjct: 175 SAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKAL 234 Query: 93 SSL-NDFQEKTDTNAQKDEQKNEQEEEQRRLKEQQRLRKNQKNQEM-----LKGLQQNLD 146 N + + +K E Q L++ N + L+ + L+ Sbjct: 235 EGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALE 294 Query: 147 QFAQKLESVK 156 LE Sbjct: 295 AEKADLEHQS 304
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 143 bits (363), Expect = 2e-44 Identities = 45/168 (26%), Positives = 71/168 (42%), Gaps = 22/168 (13%) Query: 22 NMDKETVAGDVSAKAVQSAPVSTETVQEKQEPKQEPAPVVEEKPAVESGTIIASIYFDFD 81 D ++ VS + Q P PAP V+ K T+ + + F+F+ Sbjct: 177 RPDNGMLSLGVSYRFGQGEAAPVV------APAPAPAPEVQTK----HFTLKSDVLFNFN 226 Query: 82 KYEIKESDQETLDEIVQKAKE---NHMQVLLEGNTDEFGSSEYNQALGVKRTLSVKNALV 138 K +K Q LD++ + V++ G TD GS YNQ L +R SV + L+ Sbjct: 227 KATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLI 286 Query: 139 IKGVEKDMIKTISFGETKPKCTQ-----KTR----ECYKENRRVDVKL 177 KG+ D I GE+ P K R +C +RRV++++ Sbjct: 287 SKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEV 334
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 28.9 bits (64), Expect = 0.011 Identities = 13/33 (39%), Positives = 22/33 (66%) Query: 80 IENIFANEKEDTTYIITSYLNKEELFEKKPELK 112 + N+ A+EK D ++++ L+ E FEK PE+K Sbjct: 314 VGNLGASEKSDVFLVVSTLLHCIEGFEKNPEIK 346
>PF04605#Virulence-associated protein D (VapD) Length = 125 Score = 139 bits (352), Expect = 1e-46 Identities = 30/90 (33%), Positives = 43/90 (47%) Query: 3 AITFDLDANCLNENAVNLSKVYSDIHKFMEQHGFKWQQGSVYFGDETINAVTCVATVQIL 62 AI FDL L + + + YS I KFM ++GF+ +Q S Y E IN + V L Sbjct: 7 AINFDLSTKSLEKYFKDTREPYSLIKKFMLENGFEHRQYSGYTSKEPINERRVIRIVNKL 66 Query: 63 AKQIPSFAICVKDVRMLKIEENNDLMPAIK 92 K+ CVK+ + +I E L I+ Sbjct: 67 TKKFTWLGECVKEFDITEIGEQYSLKETIQ 96
>FLAGELLIN#Flagellin signature. Length = 507 Score = 31.2 bits (70), Expect = 0.019 Identities = 15/69 (21%), Positives = 29/69 (42%), Gaps = 12/69 (17%) Query: 453 LEEAAKEKENIISQR-----LQEYLEAQANNLSSLVANLLRELESEKNRIKDADLNKISE 507 ++ A + + R +Q ++ NL + V NL S ++RI+DAD Sbjct: 424 IDSALS---KVDAVRSSLGAIQNRFDSAITNLGNTVTNL----NSARSRIEDADYATEVS 476 Query: 508 QLKEYEKLS 516 + + + L Sbjct: 477 NMSKAQILQ 485
>SECA#SecA protein signature. Length = 901 Score = 31.4 bits (71), Expect = 7e-04 Identities = 16/78 (20%), Positives = 35/78 (44%), Gaps = 12/78 (15%) Query: 4 SPTKKDYTRYSEKQLFNLINQLEQKIKKMQNDRASFKEKMAKELDKRDQNFKDKIDALNE 63 S + R +++ N+IN +E +++K+ ++ EL + F+ +++ Sbjct: 12 SRNDRTLRRM--RKVVNIINAMEPEMEKLSDE----------ELKGKTAEFRARLEKGEV 59 Query: 64 LLQKISQAFDDKRDCCFR 81 L I +AF R+ R Sbjct: 60 LENLIPEAFAVVREASKR 77
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 87.8 bits (217), Expect = 1e-22 Identities = 57/241 (23%), Positives = 106/241 (43%), Gaps = 10/241 (4%) Query: 1 MGEKKESQKVAIITGASSGIGLECALMLLDQGYKVYALSRHATLCVALNHALC------E 54 M K K+A ITGA+ GIG A L QG + A+ + + +L E Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE 60 Query: 55 SIDVDVSDSNALKEAFLNISAKEDHCDVLINSAGYGVFGSVEDTPIDEVKKQFGVNFFAL 114 + DV DS A+ E I + D+L+N AG G + +E + F VN + Sbjct: 61 AFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGV 120 Query: 115 CEVVQFCLPLLKNKPCSKIFNLSSIAGRVSMLFLGHYSASKHALEAYSDALRLELKPFNI 174 + + ++ I + S V + Y++SK A ++ L LEL +NI Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNI 180 Query: 175 QVCLIEPGPVKSNWEKTAFENDERKDSLYALEVNAAKSFYSGV-YQKALSPKAVAQKIVF 233 + ++ PG +++ + + + ++ + + + ++F +G+ +K P +A ++F Sbjct: 181 RCNIVSPGSTETDMQWSLWADENGAEQVIK---GSLETFKTGIPLKKLAKPSDIADAVLF 237 Query: 234 L 234 L Sbjct: 238 L 238
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 2004 bits (5194), Expect = 0.0 Identities = 1176/1296 (90%), Positives = 1229/1296 (94%), Gaps = 5/1296 (0%) Query: 1 MELQQTHRKINRPLVSLALVGLLVSITPQKSHAAFFTTVIIPAIVGGIATGAAVGTVSGL 60 ME+QQTHRKINRPLVSLALVG LVSITPQ+SHAAFFTTVIIPAIVGGIATGAAVGTVSGL Sbjct: 1 MEIQQTHRKINRPLVSLALVGALVSITPQQSHAAFFTTVIIPAIVGGIATGAAVGTVSGL 60 Query: 61 LGWGLKQAEEANKTPDKPDKVWRIQAGRGFNEFPNKEYDLYKSLLSSKIDGGWDWGNAAR 120 LGWGLKQAEEANKTPDKPDKVWRIQAG+GFNEFPNKEYDLYKSLLSSKIDGGWDWGNAAR Sbjct: 61 LGWGLKQAEEANKTPDKPDKVWRIQAGKGFNEFPNKEYDLYKSLLSSKIDGGWDWGNAAR 120 Query: 121 HYWVKGGQWNKLEVDMKDAVGTYKLSGLRNYTGGDLDVNMQKATLRLGQFNGNSFTSFKD 180 HYWVK GQWNKLEVDM++AVGTY LSGL N+TGGDLDVNMQKATLRLGQFNGNSFTS+KD Sbjct: 121 HYWVKDGQWNKLEVDMQNAVGTYNLSGLINFTGGDLDVNMQKATLRLGQFNGNSFTSYKD 180 Query: 181 SADRTTRVDFNAKNISIDNFLEINNRVGSGAGRKASSTVLTLQASEGITSGKNAEISLYD 240 SADRTTRVDFNAKNI IDNFLEINNRVGSGAGRKASSTVLTLQASEGITS +NAEISLYD Sbjct: 181 SADRTTRVDFNAKNILIDNFLEINNRVGSGAGRKASSTVLTLQASEGITSRENAEISLYD 240 Query: 241 GATLNLASNSVKLMGNVWMGRLQYVGAYLAPSYSTINTSKVVGEVNFNHLTVGDRNAAQA 300 GATLNLASNSVKLMGNVWMGRLQYVGAYLAPSYSTINTSKV GEVNFNHLTVGD NAAQA Sbjct: 241 GATLNLASNSVKLMGNVWMGRLQYVGAYLAPSYSTINTSKVTGEVNFNHLTVGDHNAAQA 300 Query: 301 GIIASKKTYIGTLDLWQSAGLNIIAPPEGGYKDKPNNTNSQSGAKNDKNESAKNDKQESS 360 GIIAS KT+IGTLDLWQSAGLNIIAPPEGGYKDKPN+ S + N AKNDKQESS Sbjct: 301 GIIASNKTHIGTLDLWQSAGLNIIAPPEGGYKDKPNDKPSNTTQNN-----AKNDKQESS 355 Query: 361 QNNSNTQVINPPNSGQKTEIQPTQVIDGPFAGAKDTVVNINRINTNADGTIKVGGYTASL 420 QNNSNTQVINPPNS QKTEIQPTQVIDGPFAG K+TVVNINRINTNADGTI+VGG+ ASL Sbjct: 356 QNNSNTQVINPPNSAQKTEIQPTQVIDGPFAGGKNTVVNINRINTNADGTIRVGGFKASL 415 Query: 421 TTNAANLNIGKGGVNLSNQASGRSLLVENLTGNITVDGALMVNNQVGGYALAGSSANFEF 480 TTNAA+L+IGKGG+NLSNQASGRSLLVENLTGNITVDG L VNNQVGGYALAGSSANFEF Sbjct: 416 TTNAAHLHIGKGGINLSNQASGRSLLVENLTGNITVDGPLRVNNQVGGYALAGSSANFEF 475 Query: 481 KAGVDTKNGTIAFNNNISLGRFVNLKASAHTVNFKDIDTGNGGFNTLDFSGVTNKVNINK 540 KAG DTKNGT FNN+ISLGRFVNLK AHT NFK IDTGNGGFNTLDFSGVTNKVNINK Sbjct: 476 KAGTDTKNGTATFNNDISLGRFVNLKVDAHTANFKGIDTGNGGFNTLDFSGVTNKVNINK 535 Query: 541 LITASTNVAIKNFNINELLVKTNGISVGEYTNFSEDIGNQSRINTVRLETGTRSIYSGGV 600 LITASTNVA+KNFNINEL+VKTNG+SVGEYT+FSEDIG+QSRINTVRLETGTRSIYSGGV Sbjct: 536 LITASTNVAVKNFNINELVVKTNGVSVGEYTHFSEDIGSQSRINTVRLETGTRSIYSGGV 595 Query: 601 KFKSGEKLVINDFYYAPWNYFDARNIKNVEITNKLAFGPQGSPWGTAKLMFNNLTLGPNA 660 KFK GEKLVINDFYYAPWNYFDARNIKNVEITNKLAFGPQGSPWGTAKLMFNNLTLG NA Sbjct: 596 KFKGGEKLVINDFYYAPWNYFDARNIKNVEITNKLAFGPQGSPWGTAKLMFNNLTLGQNA 655 Query: 661 VMDYSQFSNVTIQGNFINNQGTINYLVRGGNIETLSVGNAAVMSFNNDIDSATGFYKPLI 720 VMDYSQFSN+TIQG+F+NNQGTINYLVRGG + TL+VGNAA M F+N++DSATGFY+PL+ Sbjct: 656 VMDYSQFSNLTIQGDFVNNQGTINYLVRGGQVATLNVGNAAAMFFSNNVDSATGFYQPLM 715 Query: 721 KINSAQDLIKNKEHVLLKAKIIGYENASLGTNSISNANLIEQFNERLALYNNNNRMDTCV 780 KINSAQDLIKNKEHVLLKAKIIGY N S GT+SI+N NLIEQF ERLALYNNNNRMD CV Sbjct: 716 KINSAQDLIKNKEHVLLKAKIIGYGNVSAGTDSIANVNLIEQFKERLALYNNNNRMDICV 775 Query: 781 VRNTDDIKACGMAIGDQAMVNNPDNYKYLIGKAWKNIGISKTANGSKISVRYLGNATPAE 840 VRNTDDIKACG AIG+Q+MVNNP+NYKYL GKAWKNIGISKTANGSKISV YLGN+TP E Sbjct: 776 VRNTDDIKACGTAIGNQSMVNNPENYKYLEGKAWKNIGISKTANGSKISVHYLGNSTPTE 835 Query: 841 NGGNTTNLPTNTTNNARFASYALIKNAPFAQTNATPSLVAINKHNFGTIESVFELANRSE 900 NGGNTTNLPTNTTN RFASYALIKNAPFA+ +ATP+LVAIN+H+FGTIESVFELANRS Sbjct: 836 NGGNTTNLPTNTTNKVRFASYALIKNAPFARYSATPNLVAINQHDFGTIESVFELANRSN 895 Query: 901 DIDTLYANSGAQGRDLLQTLLIDSHDAGYARTMIDATSTNEITKQLNEANSALNNIASLD 960 DIDTLYANSGAQGRDLLQTLLIDSHDAGYARTMIDATS NEITKQLN A + LNNIASL+ Sbjct: 896 DIDTLYANSGAQGRDLLQTLLIDSHDAGYARTMIDATSANEITKQLNTATTTLNNIASLE 955 Query: 961 HKTSGLQTLSLSNAMILNSRLVNLSRRHTNNIDSFAKRLQALKDQKFASLESAAEVLYQF 1020 HKTSGLQTLSLSNAMILNSRLVNLSRRHTN+IDSFAKRLQALKDQ+FASLESAAEVLYQF Sbjct: 956 HKTSGLQTLSLSNAMILNSRLVNLSRRHTNHIDSFAKRLQALKDQRFASLESAAEVLYQF 1015 Query: 1021 APKYEKPTNVWANAIGGASLNSGGNTSLYGTSAGVDAYLNGEVEAIVGGFGSYGYSSFSN 1080 APKYEKPTNVWANAIGG SLNSGGN SLYGTSAGVDAYLNGEVEAIVGGFGSYGYSSFSN Sbjct: 1016 APKYEKPTNVWANAIGGTSLNSGGNASLYGTSAGVDAYLNGEVEAIVGGFGSYGYSSFSN 1075 Query: 1081 QANSLNSGANNANFGVYSRIFANQHEFDFEAQGAVGSDQSSLNFKGALLRDLNQSYNYLA 1140 QANSLNSGANN NFGVYSRIFANQHEFDFEAQGA+GSDQSSLNFK ALLRDLNQSYNYLA Sbjct: 1076 QANSLNSGANNTNFGVYSRIFANQHEFDFEAQGALGSDQSSLNFKSALLRDLNQSYNYLA 1135 Query: 1141 YGASARASYGYDFAFFRNALVLKPSVGVNYNHLGSTNFESNSTHKAALKNGASSQHLFNA 1200 Y A+ RASYGYDFAFFRNALVLKPSVGV+YNHLGSTNF+SNS K ALKNGASSQHLFNA Sbjct: 1136 YSAATRASYGYDFAFFRNALVLKPSVGVSYNHLGSTNFKSNSNQKVALKNGASSQHLFNA 1195 Query: 1201 SANVEARYYYGDTSYFYMNAGVLQEFTNFGSSNAVSLNTFKVNAARNPLNTHARVMMGGE 1260 SANVEARYYYGDTSYFYMNAGVLQEF NFGSSNAVSLNTFKVNA RNPLNTHARVMMGGE Sbjct: 1196 SANVEARYYYGDTSYFYMNAGVLQEFANFGSSNAVSLNTFKVNATRNPLNTHARVMMGGE 1255 Query: 1261 LKLAKEVFLNLGFIYLHNLISNIGHFASNLGMRYSF 1296 LKLAKEVFLNLGF+YLHNLISNIGHFASNLGMRYSF Sbjct: 1256 LKLAKEVFLNLGFVYLHNLISNIGHFASNLGMRYSF 1291
>OMS28PORIN#OMS28 porin signature. Length = 257 Score = 29.8 bits (66), Expect = 0.019 Identities = 16/51 (31%), Positives = 32/51 (62%), Gaps = 4/51 (7%) Query: 309 EEDLLVSKKRLDKIYRLKQRVLGTLGGINPNFKKEILKCMQDDLNISKALS 359 +E L+ S++ LD+ + Q+VL + G+NP+ K ++L +++KA+S Sbjct: 188 KETLMASERALDETVQEAQKVLNMVNGLNPSNKDQVLA----KKDVAKAIS 234
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 362 bits (930), Expect = e-127 Identities = 118/359 (32%), Positives = 195/359 (54%), Gaps = 14/359 (3%) Query: 4 EEKTELPSAKKIQKAREEGNVPKSMEVVGVLGLLAGLLGIFVFFIWWVDGFSEMYRHVVK 63 EKTE P+ KKI+ AR++G V KS EVV ++A + ++ + FS++ + Sbjct: 3 GEKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLMLIPAE 62 Query: 64 DFSLDFSKESVQKLFNQLAKDTFLLLLPILIILVVVAFLSNVLQFGWLFAPKVIEPKFSK 123 L FS +++ + + + + F L P+L + ++A S+V+Q+G+L + + I+P K Sbjct: 63 QSYLPFS-QALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDIKK 121 Query: 124 INPINGVKNLFSLKKLLDGSLITLKVFLAFFLGFFIFSLFLGEL------NHAALLNLQG 177 INPI G K +FS+K L++ LKV L L + I L L + L G Sbjct: 122 INPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLLG 181 Query: 178 QLLWFKSKALLLISSLLFLFFVLAFIDLAIKRRQYTNSLKMTKQEVKDEYKQQEGNPEIK 237 Q+L + L++I ++ F+ V++ D A + QY LKM+K E+K EYK+ EG+PEIK Sbjct: 182 QIL----RQLMVICTVGFV--VISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIK 235 Query: 238 AKIRQMMLKNATNKMMQEIPKANVVVTNPTHYAVALKFD-EEHPVPVVVAKGMDYLAIRI 296 +K RQ + + M + + +++VVV NPTH A+ + + E P+P+V K D + Sbjct: 236 SKRRQFHQEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTV 295 Query: 297 KGIAREHDIEIIENKTLARELYRDVKLNATIPEELFEAVAIVFAQVAKLEQERQKQKII 355 + IA E + I++ LAR LY D ++ IP E EA A V + + E+Q +++ Sbjct: 296 RKIAEEEGVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQNIEKQHSEML 354
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 276 bits (708), Expect = 2e-96 Identities = 113/245 (46%), Positives = 162/245 (66%), Gaps = 2/245 (0%) Query: 1 MRFFIFLILICPLICPLMSADSALPSVNLSLNAPNDPKQLVTTLNVIALLTLLVLAPSLI 60 MR + + + L A + LP + S P + + + +T L P+++ Sbjct: 1 MRRLLSVAPVL-LWLITPLAFAQLPGIT-SQPLPGGGQSWSLPVQTLVFITSLTFIPAIL 58 Query: 61 LVMTSFTRLIVVFSFLRTALGTQQTPPTQILVSLSLILTFFIMEPSLKKAYDTGIKPYMD 120 L+MTSFTR+I+VF LR ALGT PP Q+L+ L+L LTFFIM P + K Y +P+ + Sbjct: 59 LMMTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSE 118 Query: 121 KKISYTEAFEKSALPFKEFMLKNTREKDLALFFRIRNLPNPKTPDEVSLSVLIPAFMISE 180 +KIS EA EK A P +EFML+ TRE DL LF R+ N + P+ V + +L+PA++ SE Sbjct: 119 EKISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSE 178 Query: 181 LKTAFQIGFLLYLPFLVIDMVISSILMAMGMMMLPPVMISLPFKILVFILVDGFNLLTEN 240 LKTAFQIGF +++PFL+ID+VI+S+LMA+GMMM+PP I+LPFK+++F+LVDG+ LL + Sbjct: 179 LKTAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGS 238 Query: 241 LVASF 245 L SF Sbjct: 239 LAQSF 243
>PF01206#SirA family protein Length = 76 Score = 26.6 bits (59), Expect = 0.004 Identities = 7/22 (31%), Positives = 12/22 (54%) Query: 19 SGKEIEVLSTKPEMRIDISSFC 40 +G+ + V++T P D SF Sbjct: 31 AGEVLYVMATDPGSVKDFESFS 52
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 1738 bits (4501), Expect = 0.0 Identities = 928/1189 (78%), Positives = 1020/1189 (85%), Gaps = 57/1189 (4%) Query: 1 MTNETIDQTITPDQTPNQTDFVPQRFINNLQVAFIKVDNAVASFDPDQKPIVDKNDRDNR 60 MTNETIDQ Q + F PQ+FINNLQVAF+KVDNAVAS+DPDQKPIVDKNDRDNR Sbjct: 1 MTNETIDQ-----QPQTEAAFNPQQFINNLQVAFLKVDNAVASYDPDQKPIVDKNDRDNR 55 Query: 61 QAFEKISQLREEYANKAIKNPTKKNQYFSDFINKSNDLINKDNLIAVDSSVESFRKFGDQ 120 QAFE ISQLREEY+NKAIKNPTKKNQYFSDFINKSNDLINKDNLI V+SS +SF+KFGDQ Sbjct: 56 QAFEGISQLREEYSNKAIKNPTKKNQYFSDFINKSNDLINKDNLIDVESSTKSFQKFGDQ 115 Query: 121 RYQIFTSWVSLQKDPSKINTQQIRNFMENIIQPPISDDKEKAEFLRSAKQSFAGIIIGNQ 180 RY+IFTSWVS Q DPSKINT+ IRNFMENIIQPPI DDKEKAEFL+SAKQSFAGIIIGNQ Sbjct: 116 RYRIFTSWVSHQNDPSKINTRSIRNFMENIIQPPILDDKEKAEFLKSAKQSFAGIIIGNQ 175 Query: 181 IRSDEKFMGVFDESLKARQEAEKNAEPAGGDWLDIFLSFVFNKKQSSDLKETLNQEPRPD 240 IR+D+KFMGVFDESLK RQEAEKN EP GGDWLDIFLSF+F+KKQSSD+KE +NQEP P Sbjct: 176 IRTDQKFMGVFDESLKERQEAEKNGEPTGGDWLDIFLSFIFDKKQSSDVKEAINQEPVPH 235 Query: 241 FEQNLATTTTDIQGLPPESRDLLDERGNFFKFTLGDMEMLDVEGVADKDPNYKFNQLLIH 300 + ++ATTTTDIQGLPPE+RDLLDERGNF KFTLGDMEMLDVEGVAD DPNYKFNQLLIH Sbjct: 236 VQPDIATTTTDIQGLPPEARDLLDERGNFSKFTLGDMEMLDVEGVADIDPNYKFNQLLIH 295 Query: 301 NNALSSVLMGGHSNIEPEKVSLLYGDNGGPEARHDWNATVGYKNQQGNNVATLINAHLRN 360 NNALSSVLMG H+ IEPEKVSLLYG NGGP ARHDWNATVGYK+QQGNNVAT+IN H++N Sbjct: 296 NNALSSVLMGSHNGIEPEKVSLLYGGNGGPGARHDWNATVGYKDQQGNNVATIINVHMKN 355 Query: 361 GSGLVIVGNEDGIKNPSFYLYKEDQLTGLKQALSQEEIQNKVDFMEFLAQNNAKLDNLSE 420 GSGLVI G E GI NPSFYLYKEDQLTG ++ALSQEEIQNK+DFMEFLAQNNAKLDNLSE Sbjct: 356 GSGLVIAGGEKGINNPSFYLYKEDQLTGSQRALSQEEIQNKIDFMEFLAQNNAKLDNLSE 415 Query: 421 KEKEKFQTEIEDFQKDRKAYLDALGNDRIAFVSKKDPKHLALVTEFGNGEVSYTLKDYGK 480 KEKEKF+TEI+DFQKD KAYLDALGNDRIAFVSKKD KH AL+TEFGNG++SYTLKDYGK Sbjct: 416 KEKEKFRTEIKDFQKDSKAYLDALGNDRIAFVSKKDTKHSALITEFGNGDLSYTLKDYGK 475 Query: 481 KQDKALDGETKTTLQGSLKYDGVMFVNYSNFKYTNASKSPDKGVGTTNGVSHLEANFSKV 540 K DKALD E TLQGSLK+DGVMFV+YSNFKYTNASK+P+KGVG TNGVSHLE F+KV Sbjct: 476 KADKALDREKNVTLQGSLKHDGVMFVDYSNFKYTNASKNPNKGVGVTNGVSHLEVGFNKV 535 Query: 541 AVFNLPNLNNLAITNYIRRDLEDKLLAKGLSPQEANKLIKDFLNSNKEMVGKVSNFNKAV 600 A+FNLP+LNNLAIT+++RR+LEDKL KGLSPQEANKLIKDFL+SNKE+VGK NFNKAV Sbjct: 536 AIFNLPDLNNLAITSFVRRNLEDKLTTKGLSPQEANKLIKDFLSSNKELVGKTLNFNKAV 595 Query: 601 AEAKNTGNYDEVKKAQKDLEKSLRKREHLEKEVAKKLESRNDNKNRMEAKAQANSQKDKI 660 A+AKNTGNYDEVKKAQKDLEKSLRKREHLEKEV KKLES++ NKN+MEAKAQANSQKD+I Sbjct: 596 ADAKNTGNYDEVKKAQKDLEKSLRKREHLEKEVEKKLESKSGNKNKMEAKAQANSQKDEI 655 Query: 661 FALINQEASKEARAAAFDPNLKGIRSELSDKLENINKNLKDFGKSVDELKNGKNNDFSKA 720 FALIN+EA+++ARA A+ NLKGI+ ELSDKLEN+NKNLKDF KS DE KNGKN DFSKA Sbjct: 656 FALINKEANRDARAIAYAQNLKGIKRELSDKLENVNKNLKDFDKSFDEFKNGKNKDFSKA 715 Query: 721 EETLKALKDSVKDLGINPEWISKIENLNAALNDFKNGKNKDFSKVTQAKSDLENSIKDVI 780 EETLKALK SVKDLGINPEWISK+ENLNAALN+FKNGKNKDFSKVTQAKSDLENS+KDVI Sbjct: 716 EETLKALKGSVKDLGINPEWISKVENLNAALNEFKNGKNKDFSKVTQAKSDLENSVKDVI 775 Query: 781 INQKITDKVDNLNQAVSETKLTGDFSKVEQALAELKSLS-------------LDLGKNSD 827 INQK+TDKVDNLNQAVS K TGDFS+VEQALA+LK+ S L+ K S+ Sbjct: 776 INQKVTDKVDNLNQAVSVAKATGDFSRVEQALADLKNFSKEQLAQQAQKNESLNARKKSE 835 Query: 828 LQKSVKNGVNGTLVGNGLSKTEATTLTKNFSDIRKELNEKLFGNSNNNNNGLKNEPIYAQ 887 + +SVKNGVNGTLVGNGLS+ EATTL+KNFSDI+KELN KL +NNNNNGLKNEPIYA+ Sbjct: 836 IYQSVKNGVNGTLVGNGLSQAEATTLSKNFSDIKKELNAKLGNFNNNNNNGLKNEPIYAK 895 Query: 888 VNKKKAGQVASPEEPIYAQVAKKVSAKIDQLNEATSAINRKIDRINKIASAGKGVGGFSG 947 VNKKKAGQ AS EEPIYAQVAKKV+AKID+LN+ S G GV G Sbjct: 896 VNKKKAGQAASLEEPIYAQVAKKVNAKIDRLNQIAS---------------GLGVVG--- 937 Query: 948 AGQSASPEPIYATIDFDDANQAGFPLRRSAAVNDLSKVGLSREQELTRRIGDLNQAVSEA 1007 AGFPL+R V+DLSKVGLSR QEL ++I +LNQAVSEA Sbjct: 938 -------------------QAAGFPLKRHDKVDDLSKVGLSRNQELAQKIDNLNQAVSEA 978 Query: 1008 KTGRFDNLEQKIDELKDSTKKNALKLWVESAKQVPIGLQAKLDNYATNSHTRINSNVQSG 1067 K G F NLEQ ID+LKDSTK N + LWVESAK+VP L AKLDNYATNSH RINSN+++G Sbjct: 979 KAGFFGNLEQTIDKLKDSTKHNPMNLWVESAKKVPASLSAKLDNYATNSHIRINSNIKNG 1038 Query: 1068 TINEKATGMLTQRNPEWLKLVNDKIVAHNVGSAHLSEYDKIGFNQKNMKDYSDSFKFSTK 1127 INEKATGMLTQ+NPEWLKLVNDKIVAHNVGS LSEYDKIGFNQKNMKDYSDSFKFSTK Sbjct: 1039 AINEKATGMLTQKNPEWLKLVNDKIVAHNVGSVPLSEYDKIGFNQKNMKDYSDSFKFSTK 1098 Query: 1128 LNNAVKDIKSSFVQFLTNTFSTGS-YSLMKANVEHGVKNT-TKSGFQKS 1174 LNNAVKD S F QFLTN FST S Y L + N EHG+KN TK GFQKS Sbjct: 1099 LNNAVKDTNSGFTQFLTNAFSTASYYCLARENAEHGIKNVNTKGGFQKS 1147
>SECETRNLCASE#Bacterial translocase SecE signature. Length = 127 Score = 30.6 bits (69), Expect = 0.011 Identities = 14/72 (19%), Positives = 27/72 (37%), Gaps = 12/72 (16%) Query: 46 DGGNRLFGFPETFIYSSIFILFVTIVLSVILFQA-YEPILIVAIVIVLVALGF------- 97 G L E + + L + ++ L++ P+ +A+VI++ A G Sbjct: 9 GSGRGL----EAMKWVVVVALLLVAIVGNYLYRDIMLPLRALAVVILIAAAGGVALLTTK 64 Query: 98 KKDYRLYQRMER 109 K + R R Sbjct: 65 GKATVAFAREAR 76
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 28.6 bits (63), Expect = 0.033 Identities = 28/119 (23%), Positives = 55/119 (46%), Gaps = 16/119 (13%) Query: 24 AINTALLPSEYKKLVALGFKKIKTFHQRHDDEEITKEEKEFATNALREKLRNDRARAEQI 83 A+N AL+ +Y++ + K K D +E+ +++K EK + + +A++ Sbjct: 112 AVNFALMTRDYQEFL----KTKKLIVDAPDPKELEEQKKAL------EKEKEAKEQAQKA 161 Query: 84 QKNIEAFEKKNNSSIQKKAAKHKGLQELNETNANPLNDNPNSNSSTETKSNKDDNFDEM 142 QK+ K +++A L+ L +NP N + N N S K +++ D+M Sbjct: 162 QKD------KREKRKEERAKNRANLENLTNAMSNPQNLSNNKNLSELIKQQRENELDQM 214
>PF04335#VirB8 type IV secretion protein Length = 227 Score = 119 bits (300), Expect = 3e-35 Identities = 44/205 (21%), Positives = 74/205 (36%), Gaps = 10/205 (4%) Query: 27 KLNKANRTFKRAFYL---SMALNIAAVASIVMMMPLKKTDIFVYGIDRYTGEFKIVKRSD 83 KL A R+ K A+ + + AL A V ++ + PLK + +V +DR TGE I + Sbjct: 24 KLAAAERSKKLAWVVAGVAGALATAGVVAVAALTPLKTVEPYVITVDRNTGEASIAAKLH 83 Query: 84 A-RQIVNSEAVVDSATSKFVSLLFGYSKNSLRDRKDQLMQYCDVSFQTQAMRMFNENIRQ 142 I EAV + +V G+ + + D +M Q + R + + Q Sbjct: 84 GDATITYDEAVRKYFLATYVRYREGWIAAAREEYFDAVMVMSARPEQDRWSRFYKTDNPQ 143 Query: 143 FVDKVRA-EAIISSNIQREKVKNSPLTRLTFFITIKITPDTMENYEYITKKQVTIYYDFA 201 + A + I + +F +T T TI Y Sbjct: 144 SPQNILANRTDVFVEI-KRVSFLGGNVAQVYFTKESVTGSNS----TKTDAVATIKYKVD 198 Query: 202 RGNSSQENLIINPFGFKVFDIQITD 226 S + + NP G++V + Sbjct: 199 GTPSKEVDRFKNPLGYQVESYRADV 223
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 864 bits (2232), Expect = 0.0 Identities = 512/522 (98%), Positives = 514/522 (98%), Gaps = 1/522 (0%) Query: 1 MEQAFFKKIVGCFCLGYLFLSGVIEAAP-DIKNFNRGRVKVVNKKIAYLGDEKPITIWTS 59 M QAFFKKIVGCFCLGYLFLS IEA DIKNFNRGRVKVVNKKIAYLGDEKPITIWTS Sbjct: 1 MGQAFFKKIVGCFCLGYLFLSSAIEAVALDIKNFNRGRVKVVNKKIAYLGDEKPITIWTS 60 Query: 60 LDNVTVIQLEKDETISYITTGFNKGWSIVPNSNHIFIQPKSVKSNLMFEKEAVNFALMTR 119 LDNVTVIQLEKDETISYITTGFNKGWSIVPNSNHIFIQPKSVKSNLMFEKEAVNFALMTR Sbjct: 61 LDNVTVIQLEKDETISYITTGFNKGWSIVPNSNHIFIQPKSVKSNLMFEKEAVNFALMTR 120 Query: 120 DYQEFLKTKKLIVDAPDPKELEEQKKALEKEKEAKEQAQKVQKDKREKRKEERAKNRANL 179 DYQEFLKTKKLIVDAPDPKELEEQKKALEKEKEAKEQAQK QKDKREKRKEERAKNRANL Sbjct: 121 DYQEFLKTKKLIVDAPDPKELEEQKKALEKEKEAKEQAQKAQKDKREKRKEERAKNRANL 180 Query: 180 ENLTNAMSNPQNLSNNKNLSEFIKQQRENELDQMERLEDMQEQAQANALKQIEELNKKQA 239 ENLTNAMSNPQNLSNNKNLSE IKQQRENELDQMERLEDMQEQAQANALKQIEELNKKQA Sbjct: 181 ENLTNAMSNPQNLSNNKNLSELIKQQRENELDQMERLEDMQEQAQANALKQIEELNKKQA 240 Query: 240 EEAVKQRAKDKINIKTDKSQKSPEDNSIELSPSDSAWRTNLVVRTNKALYQFILRIAQKD 299 EEAV+QRAKDKI+IKTDKSQKSPEDNSIELSPSDSAWRTNLVVRTNKALYQFILRIAQKD Sbjct: 241 EEAVRQRAKDKISIKTDKSQKSPEDNSIELSPSDSAWRTNLVVRTNKALYQFILRIAQKD 300 Query: 300 NFASAYLTVKLEYPQRHEVSSVIEEELKKREEAKRQRELIKQENLNTTAYINRVMMASNE 359 NFASAYLTVKLEYPQRHEVSSVIEEELKKREEAKRQRELIKQENLNTTAYINRVMMASNE Sbjct: 301 NFASAYLTVKLEYPQRHEVSSVIEEELKKREEAKRQRELIKQENLNTTAYINRVMMASNE 360 Query: 360 QIINKEKIREEKQKIILDQAKALETQYVHNALKRNPVPRNYNYYQAPEKRSKHIMPSEIF 419 QIINKEKIREEKQKIILDQAKALETQYVHNALKRNPVPRNYNYYQAPEKRSKHIMPSEIF Sbjct: 361 QIINKEKIREEKQKIILDQAKALETQYVHNALKRNPVPRNYNYYQAPEKRSKHIMPSEIF 420 Query: 420 DDGTFTYFGFKNITLQPAIFVVQPDGKLSMTDAAIDPNMTNSGLRWYRVNEIAEKFKLIK 479 DDGTFTYFGFKNITLQPAIFVVQPDGKLSMTDAAIDPNMTNSGLRWYRVNEIAEKFKLIK Sbjct: 421 DDGTFTYFGFKNITLQPAIFVVQPDGKLSMTDAAIDPNMTNSGLRWYRVNEIAEKFKLIK 480 Query: 480 DKALVTVINKGYGKNPLTKNYNIKNYGELERVIKKLPLVRDK 521 DKALVTVINKGYGKNPLTKNYNIKNYGELERVIKKLPLVRDK Sbjct: 481 DKALVTVINKGYGKNPLTKNYNIKNYGELERVIKKLPLVRDK 522
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 39.3 bits (91), Expect = 2e-04 Identities = 37/260 (14%), Positives = 90/260 (34%), Gaps = 33/260 (12%) Query: 712 TPEAKKLLEEEAKESVKAYLDCVSQAKTEAEKKECEKLLTPEAKKKLEEAKKSVKAYLDC 771 P ++ + + ++KT + ++ T + ++ +EAK +VKA Sbjct: 1023 APVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQT 1082 Query: 772 VSQAKTEAEKKECEKLLTPEAKKLLEQQALDCLKNAKTDGERKKCLKDLPKDLQKKVLAK 831 A++ +E KE + T E + +++ AK + E+ + Sbjct: 1083 NEVAQSGSETKETQTTETKETATVEKEE------KAKVETEKT---------------QE 1121 Query: 832 ESLKAYKDCVSRARNEKEKKECEKLLTPEAKKLLEEAKESLKAYKDCVSQAKTEAEKKEC 891 + + ++E + + E + ++E + SQ T A+ ++ Sbjct: 1122 VPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQ----------SQTNTTADTEQP 1171 Query: 892 EKLLTPEAKKLLEEEAKESIKAYLDCVSQAKTEAEKKECEKLLTPEAKKKLEEAKKSVKA 951 K + ++ + E + + + T A + + K ++SV++ Sbjct: 1172 AKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPK--NRHRRSVRS 1229 Query: 952 YLDCVSQAKTEAEKKECEKL 971 V A T + + L Sbjct: 1230 VPHNVEPATTSSNDRSTVAL 1249 Score = 35.4 bits (81), Expect = 0.003 Identities = 31/196 (15%), Positives = 70/196 (35%), Gaps = 4/196 (2%) Query: 855 KLLTPEAKKL--LEEAKESLKAYKDCVSQAKTEAEKKECEKLLT-PEAKKLLEEEAKESI 911 L PE +K + + +E ++ P ++ + Sbjct: 979 DLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTE 1038 Query: 912 KAYLDCVSQAKTEAEKKECEKLLTPEAKKKLEEAKKSVKAYLDCVSQAKTEAEKKECEKL 971 + ++KT + ++ T + ++ +EAK +VKA A++ +E KE + Sbjct: 1039 TVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTT 1098 Query: 972 LTPEAKKLLEQQALDCLKNAKTDGERKKCLKDLPKDLQKKVLAKESLKAYKDCVSRARNE 1031 T E + +++ KT K + PK Q + + ++ A ++ + E Sbjct: 1099 ETKETATVEKEEKAKVET-EKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKE 1157 Query: 1032 KEKKECEKLLTPEAKK 1047 + + T + K Sbjct: 1158 PQSQTNTTADTEQPAK 1173 Score = 35.4 bits (81), Expect = 0.003 Identities = 32/222 (14%), Positives = 86/222 (38%), Gaps = 7/222 (3%) Query: 989 KNAKTDGERKKCLKDLP-KDLQKKVLAKESLKAYKDCVSRARNEKEKKECEKLLTPEAKK 1047 + ++ E + + P ++ + ++ ++ ++ ++ T + ++ Sbjct: 1008 PSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNRE 1067 Query: 1048 LLEEAKESLKAYKDCLSQARNEEERRACEKLLTPEAKKLLEE--AKESLKAYKDCVSRAR 1105 + +EAK ++KA A++ E + + T E + +E AK + ++ Sbjct: 1068 VAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTS 1127 Query: 1106 NEKEKQECEKLLTPEAKKLLEQQALDCLKNAK----TEAEKKRCAKDLPKDLQKKVLAKE 1161 KQE + + P+A+ E +K + T A+ ++ AK+ ++++ V Sbjct: 1128 QVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTEST 1187 Query: 1162 SVKAYLDCVSRARNEKDKKECEKLLTPEAKKLLEEAKESLKA 1203 +V V N + + + K + S+++ Sbjct: 1188 TVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRS 1229 Score = 32.7 bits (74), Expect = 0.017 Identities = 26/177 (14%), Positives = 66/177 (37%), Gaps = 4/177 (2%) Query: 628 KARNEKEKKECEKLLTPEAKKKLEQQVLDCLKNAKTDEERKKCLKDLPKD--LQSDILAK 685 + NE+ + E + P A + +N+K + + + + + Q+ +AK Sbjct: 1011 PSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAK 1070 Query: 686 ESLKAYKDCVSQAKTEAEKKECEKLLTPEAKKLLEEEAKESVKAYLDCVSQAKTEAEKKE 745 E+ K + E ++ T E K+ E +E K + + + Sbjct: 1071 EAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVS 1130 Query: 746 CEKLLTPEAKKKLEEAKKSVKAYL--DCVSQAKTEAEKKECEKLLTPEAKKLLEQQA 800 ++ + + + E A+++ + SQ T A+ ++ K + ++ + + Sbjct: 1131 PKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTEST 1187 Score = 32.0 bits (72), Expect = 0.034 Identities = 29/183 (15%), Positives = 60/183 (32%), Gaps = 15/183 (8%) Query: 1065 QARNEEERRACEKLLTP--------EAKKLLEEAKESLKAYKDCVSRARNEKEKQECEKL 1116 + NEE R E + P + + E +K+ K + A E Q E Sbjct: 1011 PSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDAT-ETTAQNREVA 1069 Query: 1117 LTPEAKKLLEQQALDCLKNAKTEAEKKRCAKDLPKDLQKKVLAKESVKAYLDCVSRARNE 1176 ++ Q + ++ E + ++K+ AK + + Sbjct: 1070 KEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQV 1129 Query: 1177 KDKKECEKLLTPEAKKLLEEAKESLKAYKDCLSQARNEEERRACEKLLTPEARKLLEQEV 1236 K+E + + P+A+ E + + +++ A + E +EQ V Sbjct: 1130 SPKQEQSETVQPQAEPARENDPTVN------IKEPQSQTNTTADTEQPAKETSSNVEQPV 1183 Query: 1237 KKS 1239 +S Sbjct: 1184 TES 1186
>PF07201#Hypersensitivity response secretion protein HrpJ Length = 293 Score = 29.0 bits (65), Expect = 0.033 Identities = 14/76 (18%), Positives = 26/76 (34%), Gaps = 15/76 (19%) Query: 277 APENSKEKLIEELIANSQLIANEEEREKKLLVEKEKQ--------EAELAKY--KLKDLE 326 S + EE+ E +E L K E ++ +Y K+ +LE Sbjct: 44 GTLQSIADMAEEVTF-----VFSERKELSLDKRKLSDSQARVSDVEEQVNQYLSKVPELE 98 Query: 327 NQKKLKALEAELKKKN 342 ++ + L + L Sbjct: 99 QKQNVSELLSLLSNSP 114
>PF05211#Neuraminyllactose-binding hemagglutinin Length = 260 Score = 261 bits (669), Expect = 6e-90 Identities = 63/268 (23%), Positives = 118/268 (44%), Gaps = 39/268 (14%) Query: 18 KTLISLGISSVLVGCTIKPVAEVKPQNQQEKPIQVNEKIQTTQKVTPFNFNYSLHVAQAA 77 K L+ + ++LVGC+ I+T + N+ + A Sbjct: 14 KCLLGASVVALLVGCS-------------------PHIIETNEVALKLNY-HPASEKVQA 53 Query: 78 QNYRLIGILAPRIQVSDNL-KPYIDKFQDALINQIQTIFEKRGYQTLFF--KDESALTLQ 134 + + I +L P Q SDN+ K Y +KF++ +++ I + +GY+ + D+ + Sbjct: 54 LDEK-ILLLRPAFQYSDNIAKEYENKFKNQTTLKVEQILQNQGYKVINVDSSDKDDFSFA 112 Query: 135 DKRKLFAVLDVKGWVGVLEDLKVNLKDPNNPNL--GTLVDQ------SSGSVWFSFYEPE 186 K++ + + + G + + D K ++ + P L T +D+ +G V + EP Sbjct: 113 QKKEGYLAVAMNGEIVLRPDPKRTIQKKSEPGLLFSTGLDKMEGVLIPAGFVKVTILEPM 172 Query: 187 SNRVVHDFAVEVGTF---QAITYTYKQSNSGGFNSSNSIIHEDLEKNKEDAIHQILNKIY 243 S + F +++ + T S+SGG S+ N DAI LNKI+ Sbjct: 173 SGESLDSFTMDLSELDIQEKFLKTTHSSHSGGLVSTMV----KGTDNSNDAIKSALNKIF 228 Query: 244 ALIMKKAVTELTEKNISQYKEAIDRMKG 271 A IM++ +LT+KN+ Y++ +KG Sbjct: 229 ANIMQEIDKKLTQKNLESYQKDAKELKG 256
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 198 bits (504), Expect = 1e-57 Identities = 115/461 (24%), Positives = 190/461 (41%), Gaps = 67/461 (14%) Query: 3 NIRNIAVIAHVDHGKTTLVDGLLSQSGTFSEREKVDE--RVMDSNDLERERGITILSKNT 60 I NI V+AHVD GKTTL + LL SG +E VD+ D+ LER+RGITI + T Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 61 AIYYKDTKINIIDTPGHADFGGEVERVLKMVDGVLLLVDAQEGVMPQTKFVVKKALSFGI 120 + +++TK+NIIDTPGH DF EV R L ++DG +LL+ A++GV QT+ + GI Sbjct: 62 SFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGI 121 Query: 121 CPIVVVNKIDKPAAEPDRVVDEVFDLF---------VAMGASDKQLDFPV-----VYAAA 166 I +NKID+ + V ++ + V + + +F Sbjct: 122 PTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEG 181 Query: 167 RDGYAMKSLDDE----------------------------KKNL--EPLFETILEHVPSP 196 D K + + K N+ + L E I S Sbjct: 182 NDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSS 241 Query: 197 SGSVDEPLQMQIFTLDYDNYVGKIGIARVFNGSVKKNESVLLMKSDGSKENGRITKLIGF 256 + L ++F ++Y ++ R+++G + +SV + KE +IT++ Sbjct: 242 THRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRI----SEKEKIKITEMYTS 297 Query: 257 LGLARTEIENAYAGDIVAIAG--FSAMDV-GDSVVDPTNPMPLDPMHLEEPTMSVYFAVN 313 + +I+ AY+G+IV + V GD+ + P +P P + + Sbjct: 298 INGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLPQRERIENP----LPLLQTTVEPS 353 Query: 314 DSPLAGLEGKHVTANKLKDRLLKEMQTNIAMKCEEMGEGKFKVSGRGELQITILAENLRR 373 + + D LL+ + + +S G++Q+ + L+ Sbjct: 354 KPQQREMLLDALLEISDSDPLLRYYVDSAT--------HEIILSFLGKVQMEVTCALLQE 405 Query: 374 E-GFEFSISRPEVIIKEENGVKCEPFEHLVIDTPQDFSGAI 413 + E I P VI E K E H+ + P F +I Sbjct: 406 KYHVEIEIKEPTVIYMERPLKKAEYTIHIEVP-PNPFWASI 445 Score = 41.8 bits (98), Expect = 8e-06 Identities = 20/80 (25%), Positives = 30/80 (37%), Gaps = 1/80 (1%) Query: 396 EPFEHLVIDTPQDFSGAIIERLGKRKAEMKAMNPMSDGYTRLEFEIPARGLIGYRSEFLT 455 EP+ I PQ++ K A + + + L EIPAR + YRS+ Sbjct: 537 EPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQ-LKNNEVILSGEIPARCIQEYRSDLTF 595 Query: 456 DTKGEGVMNHSFLEFRPFSG 475 T G V + +G Sbjct: 596 FTNGRSVCLTELKGYHVTTG 615
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 27.5 bits (61), Expect = 0.033 Identities = 17/59 (28%), Positives = 25/59 (42%), Gaps = 8/59 (13%) Query: 32 FVIVAWLFRF--KSIAFSILITLLVILVDIWVYSDVRQFLL-DTASSPILLLVALLIKW 87 V VA ++A +L +LV L I D+ + LL D + P+L LL Sbjct: 121 SVAVAMTLAPGWGTLAALLLTWVLVALTFI----DLDKMLLPDQLTLPLLWG-GLLFNL 174
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 28.0 bits (62), Expect = 0.015 Identities = 15/49 (30%), Positives = 21/49 (42%), Gaps = 3/49 (6%) Query: 102 RGETILKALERIAFE---EFQLNSLHLEVMENNFKAIAFYEKNHYELEG 147 R + + AL A E E L LE + N A FY K+H+ + Sbjct: 102 RKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGA 150
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 190 bits (485), Expect = 4e-63 Identities = 51/172 (29%), Positives = 84/172 (48%), Gaps = 18/172 (10%) Query: 56 GERPLFADRRAMKPNDLITIIVSEKASANYSSS----KDYKSASGGNSTPPRLTYNGLDE 111 G +PLF DRR D +TI++ E SA+ SSS +D K+ G ++ P L GL Sbjct: 61 GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYL--QGLFG 118 Query: 112 RKKQEAQYLDDKNNYNFTKSSNNTNFKGGGSQKKSEDLEIVLSARIIKVLENGNYFIYGN 171 + + + S F G G S L+ + +VL NGN + G Sbjct: 119 NARADVEA------------SGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGE 166 Query: 172 KEVLVDGEKQILKVSGVIRPYDIERNNTIQSKFLADAKIEYTNLGHLSDSNK 223 K++ ++ + ++ SGV+ P I +NT+ S +ADA+IEY G+++++ Sbjct: 167 KQIAINQGTEFIRFSGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQN 218
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 74.3 bits (182), Expect = 7e-16 Identities = 50/262 (19%), Positives = 99/262 (37%), Gaps = 6/262 (2%) Query: 197 QEGETLKDEEVSKELETQEELEIPKEETQEQAKEQE-PIKEETQENKEEKQEKTQEEVKE 255 + +T+ ++ Q ++ +E A+ E P+ E E E K+ Sbjct: 987 KRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQ 1046 Query: 256 ETQEQAKEQEPIKEETQENKE-EKQEKTQEEVKEETQEQAK-EQEPIKEETQENKEEKQE 313 E++ K ++ E T +N+E K+ K+ + +T E A+ E + +T E KE Sbjct: 1047 ESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATV 1106 Query: 314 KTQEEVKEETQEQIKEQEPIKEETQEIKEEKQEKTQDSPSVQELEAMQELVKEIQENSNG 373 + +E+ K ET++ ++ P K+E+ E Q +KE Q +N Sbjct: 1107 EKEEKAKVETEKT--QEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNT 1164 Query: 374 QEDKKETQENTETPQELEKQELEKQEKTQESAETPQDVETPQEKETQENTETPQEKEIPQ 433 D ++ + T + E E E P+ TP + N+E+ + + Sbjct: 1165 TADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPE-NTTPATTQPTVNSESSNKPKNRH 1223 Query: 434 ELEKQELETPQEEIQENTETPQ 455 + + E ++ Sbjct: 1224 RRSVRSVPHNVEPATTSSNDRS 1245 Score = 72.0 bits (176), Expect = 3e-15 Identities = 48/272 (17%), Positives = 91/272 (33%), Gaps = 21/272 (7%) Query: 220 PKEETQEQAKEQEPIKEETQENKEEKQEKTQEEVKEETQEQA---------KEQEPIKEE 270 P+ E + Q + I + + E E E E Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAE 1042 Query: 271 TQENKEEKQEKTQEEVKEETQEQAKEQEPIKEETQENKEEKQEKTQEEVKEETQEQIKEQ 330 + + + EK +++ E T + + + K + N + + +ETQ ++ Sbjct: 1043 NSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKE 1102 Query: 331 EPIKEETQEIKEEKQEKTQDSPSVQELEAMQELVKEIQENSNGQEDKKETQENTETPQEL 390 E+ ++ K E EKTQ+ P V + ++ E + + + N + PQ Sbjct: 1103 TATVEKEEKAKVET-EKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQ 1161 Query: 391 EKQELEKQEKTQESAETPQDVETPQEKETQENTETPQEKEIPQELEKQELETPQEEIQEN 450 + Q + ET +VE P + T NT E P+ + N Sbjct: 1162 TNTT---ADTEQPAKETSSNVEQPVTESTTVNT-GNSVVENPENTTPATTQP-----TVN 1212 Query: 451 TETPQKLETQEDHYESIEDIPEPVMAQAMGEE 482 +E+ K + + H S+ +P V Sbjct: 1213 SESSNKPKNR--HRRSVRSVPHNVEPATTSSN 1242 Score = 63.5 bits (154), Expect = 1e-12 Identities = 39/261 (14%), Positives = 91/261 (34%), Gaps = 13/261 (4%) Query: 167 DQEEKEEVKEEEKEEVKETPQEEKP----KDDEIQEGETLKDEEVSKELETQE----ELE 218 + E++ + + Q + P ++EI + + ++ Sbjct: 984 EVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAEN 1043 Query: 219 IPKEETQEQAKEQEPIKEETQENKEEKQEKTQEEVKEETQEQAK-EQEPIKEETQENKEE 277 +E + EQ+ + Q + K+ K+ + +T E A+ E + +T E KE Sbjct: 1044 SKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKET 1103 Query: 278 KQEKTQEEVKEETQEQAKEQEPIKEET--QENKEEKQEKTQEEVKEETQEQIKEQEPIKE 335 + +E+ K ET++ + + + + QE E Q + + + + IKE + Sbjct: 1104 ATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTN 1163 Query: 336 ETQEIKEEKQEKTQDSPSVQELEAMQELVKEIQENS-NGQEDKKETQENTETPQELEKQE 394 T + ++ +E + + + EN N + N+E+ K Sbjct: 1164 TTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSES-SNKPKNR 1222 Query: 395 LEKQEKTQESAETPQDVETPQ 415 + ++ P + Sbjct: 1223 HRRSVRSVPHNVEPATTSSND 1243 Score = 58.2 bits (140), Expect = 7e-11 Identities = 34/221 (15%), Positives = 81/221 (36%), Gaps = 21/221 (9%) Query: 169 EEKEEVKEEEKEEVKETP-QEEKPKDDEIQEGETLKDEEVSKELETQEELEIPKEETQEQ 227 E E V E K+E K E+ + Q E K+ + + + TQ E+ + ++ + Sbjct: 1035 ETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQT-NEVAQSGSETK 1093 Query: 228 AKEQEPIKEETQENKEEKQEKTQEEVKEETQEQAKEQEPIKEETQENKEEKQEKTQEEVK 287 + KE KEEK + E+ +E + ++ K+E+ E Q + + Sbjct: 1094 ETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSP---------KQEQSETVQPQAE 1144 Query: 288 EETQEQAK---EQEPIKEETQENKEEKQEKTQEEVKEETQEQIK-------EQEPIKEET 337 + ++ + T + E+ ++T V++ E + P Sbjct: 1145 PARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTP 1204 Query: 338 QEIKEEKQEKTQDSPSVQELEAMQELVKEIQENSNGQEDKK 378 + ++ + P + +++ + ++ + D+ Sbjct: 1205 ATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRS 1245 Score = 56.2 bits (135), Expect = 2e-10 Identities = 47/260 (18%), Positives = 89/260 (34%), Gaps = 25/260 (9%) Query: 310 EKQEKTQEEVKEETQEQIKEQEPIKEETQEIKEEKQEKTQDSPSVQELEAMQELVKEIQE 369 EK+ +T + T I+ P E E P+ E V E + Sbjct: 986 EKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSK 1045 Query: 370 NSNGQEDKKETQENTETPQ-----ELEKQELEKQEKTQESAETPQDVETPQEKETQENTE 424 + +K E T Q + K ++ +T E A++ + + Q ET+E Sbjct: 1046 QESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKE--- 1102 Query: 425 TPQEKEIPQELEKQELETPQEEIQENTETPQKLE------------TQEDHYESIEDIPE 472 E +E K E E QE + ++ K E + D +I++ Sbjct: 1103 -TATVE-KEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQS 1160 Query: 473 PVMAQAMGEELPFLNEAVAKIPNNENDTETPKESVIKTPQEKEESDKTSSPLELRLNLQD 532 A E+ + + P E+ T SV++ P+ + + + Sbjct: 1161 QTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQP---TVNSESSN 1217 Query: 533 LLKSLNQESLKSLLENKTLS 552 K+ ++ S++S+ N + Sbjct: 1218 KPKNRHRRSVRSVPHNVEPA 1237 Score = 51.2 bits (122), Expect = 1e-08 Identities = 29/166 (17%), Positives = 57/166 (34%), Gaps = 7/166 (4%) Query: 150 LGQEEPNNEEQLLPTLNDQEEKEEVKEEEKEEVKETPQ---EEKPKDDEIQEGETLKDEE 206 G E + E++E+ K E E+ +E P+ + PK + Q E Sbjct: 1088 SGSETKETQTTETKETATVEKEEKAKVE-TEKTQEVPKVTSQVSPK--QEQSETVQPQAE 1144 Query: 207 VSKELETQEELEIPKEETQEQAKEQEPIKEETQENKEEKQEKTQEEVKEETQEQAKEQEP 266 ++E + ++ P+ +T A ++P KE + ++ E T E + P Sbjct: 1145 PARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTP 1204 Query: 267 IKEETQENKEEKQEKTQEEVKEETQEQAKEQEPIKEETQENKEEKQ 312 + N E K + + + EP + + Sbjct: 1205 ATTQPTVN-SESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVAL 1249 Score = 48.1 bits (114), Expect = 1e-07 Identities = 33/192 (17%), Positives = 69/192 (35%), Gaps = 11/192 (5%) Query: 142 ENLGDLEALGQEEPNNEEQLLPTLNDQEEKEEVKEEEKEEVKETPQEEKPKDDEIQEGET 201 E + +E +N + T + E KE + E KET EK + +++ +T Sbjct: 1060 ETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKT 1119 Query: 202 LKDEEVSKELETQEELEIPKEETQEQAKEQEPIKEETQENKEEKQEKTQEEVKEETQEQA 261 + +V+ ++ ++E + E A+E +P + + E+ +ET Sbjct: 1120 QEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNV 1179 Query: 262 KEQEPIKEETQEN---------KEEKQEKTQEEVKEETQEQAKEQEPIKEETQENKEEKQ 312 ++ P+ E T N + TQ V E+ + K + + + E Sbjct: 1180 EQ--PVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPA 1237 Query: 313 EKTQEEVKEETQ 324 + + Sbjct: 1238 TTSSNDRSTVAL 1249
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.011 Identities = 9/18 (50%), Positives = 11/18 (61%) Query: 8 LILSGPSGAGKSTLTKYL 25 ++L G G GKSTL L Sbjct: 599 VVLEGTGGIGKSTLINTL 616
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 46.0 bits (109), Expect = 1e-07 Identities = 56/271 (20%), Positives = 104/271 (38%), Gaps = 16/271 (5%) Query: 28 LILSGSLTPNQSFQLGIAVLMGYVFGSFLIQFLSPLMSLESIAKISFALIALSFLICYFD 87 L+ S +T + L + LM + L LS + +S A A+ + I Sbjct: 35 LVHSNDVTAHYGILLALYALMQFACAPVLGA-LSDRFGRRPVLLVSLAGAAVDYAI--MA 91 Query: 88 SIPFFW-LWIWRFIAGVASSALMILVAPLSLPYIKENKKALVGGFIFSAVGIGSVFSGFV 146 + PF W L+I R +AG+ + A + +++A GF+ + G G V + Sbjct: 92 TAPFLWVLYIGRIVAGI-TGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVL 150 Query: 147 LPWISSYNIKWAWIFLGGSCLIAFILSLIGLK-TRSLRRKSVKKEESAFKIPFHL----- 200 + ++ + + F+ L + R+ +++E F Sbjct: 151 GGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMT 210 Query: 201 ---WLLLVSCALNAIGFLPHTLFWVDYLIRHLNISPTIAGTSWALFG-FGATLGSLISGP 256 L+ V + +G +P L WV + + T G S A FG + ++I+GP Sbjct: 211 VVAALMAVFFIMQLVGQVPAAL-WVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGP 269 Query: 257 MAQKLGAKNANIFILILKSIACFLPIFFHQI 287 +A +LG + A + +I L F + Sbjct: 270 VAARLGERRALMLGMIADGTGYILLAFATRG 300
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 60.4 bits (146), Expect = 7e-13 Identities = 61/263 (23%), Positives = 109/263 (41%), Gaps = 29/263 (11%) Query: 4 LKGKKGLIVGVANNKSIAYGIAQSCFNQGATL-AFTYLNESLEKRVRPIAQELNSPYVYE 62 ++GK I G A + I +A++ +QGA + A Y E LEK V + E + Sbjct: 6 IEGKIAFITGAA--QGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP 63 Query: 63 LDVSQEEHFKPLYDSVKKDLGSLDFIVHSVAF--------APKEALEGSLLETSKSAFNT 114 DV + +++++G +D +V+ E E + S FN Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 115 AMEISVYSLIELTNTLKPLLNNGASVLTLSYLGSTKYMAHYNVMGLAKAALESAVRYLAV 174 + +S Y + + ++ + +N A V S MA Y +KAA + L + Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTS-------MAAY---ASSKAAAVMFTKCLGL 173 Query: 175 DLGKHNIRVNALSAGPIRT-----LASSGIADFRMILKWNE---INAPLRKNVSLEEVGN 226 +L ++NIR N +S G T L + ++I E PL+K ++ + Sbjct: 174 ELAEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIAD 233 Query: 227 AGMYLLSSLSSGVSGEVHFVDAG 249 A ++L+S + ++ VD G Sbjct: 234 AVLFLVSGQAGHITMHNLCVDGG 256
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 33.5 bits (76), Expect = 0.001 Identities = 37/133 (27%), Positives = 58/133 (43%), Gaps = 15/133 (11%) Query: 79 LNLDPSKQESDLDKVADNVKKQENDAFKMPIQTNQTQTEMKTTEETQEAKKELKAVEHTL 138 PS+ + VA+N K++ K + + T+T + E +EAK +KA T Sbjct: 1029 APATPSETT---ETVAENSKQESKTVEKN--EQDATETTAQNREVAKEAKSNVKANTQTN 1083 Query: 139 MSAQ-----KETQAVAKKETPHK----KPKV-TPKDKEAHKDKAKHAAKEPKAKKEAHKE 188 AQ KETQ KET K KV T K +E K ++ + K+ +++ + Sbjct: 1084 EVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQA 1143 Query: 189 VPKKANSKTNLAK 201 P + N T K Sbjct: 1144 EPARENDPTVNIK 1156 Score = 32.0 bits (72), Expect = 0.002 Identities = 26/147 (17%), Positives = 52/147 (35%), Gaps = 14/147 (9%) Query: 50 PKETFLQTDSGMQKIGNTKDEKKDDAFESLNLDPSKQESDLDKVADNVKKQENDAFKMPI 109 P ET ++ T ++ + DA E+ + + V N Q N+ + Sbjct: 1033 PSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKAN--TQTNEVAQSGS 1090 Query: 110 QTNQTQTEMKTTEETQEAKKELKAVEHTLMSAQKETQAVAKKETPHKKPKVTPKDKEAHK 169 +T +TQT T E +++ K + +E P +V+PK +++ Sbjct: 1091 ETKETQTTETKETATVEKEEKAKV------------ETEKTQEVPKVTSQVSPKQEQSET 1138 Query: 170 DKAKHAAKEPKAKKEAHKEVPKKANSK 196 + + KE + N+ Sbjct: 1139 VQPQAEPARENDPTVNIKEPQSQTNTT 1165
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.008 Identities = 14/59 (23%), Positives = 23/59 (38%), Gaps = 1/59 (1%) Query: 23 IKPQESLAILGVSGSGKSTLLSHLATMLKPDSGTISLLEHQDIY-ALNSKKLLELRRLK 80 K S+ + G G GKSTL++ L + + +D Y + EL + Sbjct: 593 CKFDYSVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIAGIVAYELSEMT 651
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 433 bits (1116), Expect = e-149 Identities = 168/570 (29%), Positives = 283/570 (49%), Gaps = 59/570 (10%) Query: 10 RLILAIALSFLFIALYSYFFQKPNQT--TTQTTKQETTNNHTATNSNTPNAFSAAQTIPQ 67 R +L IAL F+ ++ + Q N QTT+ TT +A + P + + Sbjct: 5 RNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAAGSAADQGVPASGQGKLISVK 64 Query: 68 ENLLSAISFEHARIEIDSLGR--IKQVYLKDKKYLTPKQKGFLEHVSHLFNPKANPQTPL 125 ++L + I++ G + + K L Q L S F +A Sbjct: 65 TDVL--------DLTINTRGGDVEQALLPAYPKELNSTQPFQLLETSPQFIYQAQSGLTG 116 Query: 126 KELPLLAADKLKPLEVRFLDPTLNNKAFNTPYSASKTTLGPNEQLV--LTQDLGALTIIK 183 ++ P A+ +PL +N A G NE V D T K Sbjct: 117 RDGPDNPANGPRPL-------------YNVEKDAYVLAEGQNELQVPMTYTDAAGNTFTK 163 Query: 184 TLTFYDDLHYDLQIAFKSPN--------NIIPSYVITNGYKPVADLDS-----YTFSGVL 230 T Y + + + N + + P D S +TF G Sbjct: 164 TFVLKRG-DYAVNVNYNVQNAGEKPLEISSFGQLKQSITLPPHLDTGSSNFALHTFRGAA 222 Query: 231 LENNDKKIEKIE---DKDAKEIKRFSNTLFLSSVDRYFTTLLFTKDPQGFEALIDSEIGT 287 D+K EK + D + + S +++ + +YF T + G + +G Sbjct: 223 YSTPDEKYEKYKFDTIADNENLNISSKGGWVAMLQQYFATAWIPHN-DGTNNFYTANLG- 280 Query: 288 KNPLGFISLKNEA-----------NLHGYIGPKDYRSLKAISPMLTDVIEYGLITFFAKG 336 N + I K++ N ++GP+ + A++P L ++YG + F ++ Sbjct: 281 -NGIAAIGYKSQPVLVQPGQTGAMNSTLWVGPEIQDKMAAVAPHLDLTVDYGWLWFISQP 339 Query: 337 VFVLLDYLYQFVGNWGWAIILLTIIVRLILYPLSYKGMVSMQKLKEIAPKMKELQEKYKG 396 +F LL +++ FVGNWG++II++T IVR I+YPL+ SM K++ + PK++ ++E+ Sbjct: 340 LFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGD 399 Query: 397 EPQKLQAHMMQLYKKHGANPLGGCLPLILQIPVFFAIYRVLYNAVELKSSEWILWIHDLS 456 + Q++ MM LYK NPLGGC PL++Q+P+F A+Y +L +VEL+ + + LWIHDLS Sbjct: 400 DKQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYYMLMGSVELRQAPFALWIHDLS 459 Query: 457 IMDPYFILPLLMGASMYWHQSVTPSSVTDPMQAKIFKFLPLLFTIFLITFPAGLVLYWTT 516 DPY+ILP+LMG +M++ Q ++P++VTDPMQ KI F+P++FT+F + FP+GLVLY+ Sbjct: 460 AQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIV 519 Query: 517 NNILSVLQQLIINKVLENKKRMHAQNKKES 546 +N+++++QQ +I + LE K+ +H++ KK+S Sbjct: 520 SNLVTIIQQQLIYRGLE-KRGLHSREKKKS 548
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 35.6 bits (82), Expect = 4e-04 Identities = 31/134 (23%), Positives = 52/134 (38%), Gaps = 25/134 (18%) Query: 216 LSIVGKPNAGKSSLLNAMLLEERA---LVSDIKGTTR-DTIEE-------------VIEL 258 + ++ +AGK++L ++L A L S KGTTR D + Sbjct: 6 IGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQW 65 Query: 259 QGHKVRLIDTAGIRESTDKIERLGIEKSLKSLESCDIVLGVFDLSKPLEKEDFNLIDTLN 318 + KV +IDT G + ++ R SL D + + ++ + L L Sbjct: 66 ENTKVNIIDTPGHMDFLAEVYR--------SLSVLDGAILLISAKDGVQAQTRILFHALR 117 Query: 319 RAKKPCIVVLNKND 332 + P I +NK D Sbjct: 118 KMGIPTIFFINKID 131
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 33.8 bits (77), Expect = 0.002 Identities = 13/27 (48%), Positives = 15/27 (55%) Query: 49 EQTIATTQEKPKPKPKPKPKPKPITPQ 75 + EKPKPKPKPKPKP + Sbjct: 82 PKEAPVVIEKPKPKPKPKPKPVKKVQE 108 Score = 31.1 bits (70), Expect = 0.011 Identities = 10/26 (38%), Positives = 10/26 (38%) Query: 46 QTQEQTIATTQEKPKPKPKPKPKPKP 71 KPKPKPKPKP Sbjct: 75 PEPIPEPPKEAPVVIEKPKPKPKPKP 100
>FLAGELLIN#Flagellin signature. Length = 507 Score = 28.5 bits (63), Expect = 0.036 Identities = 15/62 (24%), Positives = 29/62 (46%), Gaps = 7/62 (11%) Query: 156 KAIKNVNKVLDDENVEKFKHILASIDDLIANLDSRKA-------QFDSLIGNANNLVSNV 208 + + + + LASID ++ +D+ ++ +FDS I N N V+N+ Sbjct: 400 SGVSTLINEDAAAAKKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNL 459 Query: 209 NN 210 N+ Sbjct: 460 NS 461
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 221 bits (565), Expect = 2e-77 Identities = 66/148 (44%), Positives = 94/148 (63%) Query: 4 IGIYPGTFDPVTNGHIDIIHRSSELFEKLIVAVAHSSAKNPMFSLKERLEMIQLATKSFK 63 IYPG+FDP+T GH+DII R LF+++ VAV + K PMFS++ERLE I A Sbjct: 2 NAIYPGSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPMFSVQERLEQIAKAIAHLP 61 Query: 64 NVECVAFEGLLANLAKEYHCKVLVRGLRVVSDFEYELQMGYANKSLNHELETLYFMPTLQ 123 N + +FEGL N A++ ++RGLRV+SDFE ELQM NK+L +LET++ + + Sbjct: 62 NAQVDSFEGLTVNYARQRQAGAILRGLRVLSDFELELQMANTNKTLASDLETVFLTTSTE 121 Query: 124 NAFISSSIVRSIILHKGNASHLVPKEIH 151 +F+SSS+V+ + GN H VP + Sbjct: 122 YSFLSSSLVKEVARFGGNVEHFVPSHVA 149
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 34.1 bits (78), Expect = 6e-04 Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 1/67 (1%) Query: 297 PLIFMMGFVWPFESLPSYLQAFVQIVPAYHAISLLGRLNQMHAEFIDVSIHFYALIAIFI 356 P++F+ G V+P + LP Q + +P H+I L+ R + +DV H AL + Sbjct: 188 PILFLSGAVFPVDQLPIVFQTAARFLPLSHSIDLI-RPIMLGHPVVDVCQHVGALCIYIV 246 Query: 357 ASFIGSV 363 F S Sbjct: 247 IPFFLST 253
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 47.1 bits (112), Expect = 5e-08 Identities = 27/200 (13%), Positives = 64/200 (32%), Gaps = 29/200 (14%) Query: 8 KNKAILIGGGALLLGLIVLFYLAYRP--KAEVLQGFL--EAREYSVSSKVPGRIEKVFVK 63 + L+ + +I G L R + ++++ VK Sbjct: 54 SRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVK 113 Query: 64 KGDHIKKGDLVFSISSPELEAKLAQAEAGHKAAK-------ALSDEVKRGSRDETINSAR 116 +G+ ++KGD++ +++ EA + ++ A+ LS ++ E Sbjct: 114 EGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDE 173 Query: 117 DIWQAAKSQATLAKETYKRVQDLYDNGVASLQKRDEAYAAYESTKYNESAAYQKYKMALG 176 +Q ++E R+ L E ++ +++ KY + K + Sbjct: 174 PYFQNV------SEEEVLRLTSLI----------KEQFSTWQNQKYQKELNLDKKRAERL 217 Query: 177 GASSESKIAAKAKESAALGQ 196 ++I S Sbjct: 218 TV--LARINRYENLSRVEKS 235
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 29.0 bits (65), Expect = 0.050 Identities = 13/59 (22%), Positives = 26/59 (44%), Gaps = 2/59 (3%) Query: 56 IGGYMAMNIGANDVSNNVGPAVGSKAISMGGAILIAGVCEMLGAIIAGGEVVSTIKGRI 114 G ++M++ A D++ +G+ G I I V G + G E++ + R+ Sbjct: 295 TVGTVSMDMLAVDLTPCPQAGIGTPVELWGKEIKIDDVAAAAGTV--GYELMCALALRV 351
>INVEPROTEIN#Salmonella/Shigella invasion protein E (InvE) signature. Length = 372 Score = 28.5 bits (63), Expect = 0.039 Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 10/69 (14%) Query: 158 LLQKAQNIKVFRLKD----KTLESYAEAKEAFFEDKYWILHDTIIYEMP------LSFEL 207 LL++ +K+ R D TL SY+ K E+ W+L + + P L+ + Sbjct: 246 LLRRLTQLKMLRSADLLFVSTLLSYSFTKAFNAEESSWLLLMLSLLQQPHEVDSLLADII 305 Query: 208 GANALNATH 216 G NAL +H Sbjct: 306 GLNALLLSH 314
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 35.2 bits (81), Expect = 5e-04 Identities = 9/51 (17%), Positives = 24/51 (47%), Gaps = 4/51 (7%) Query: 125 TVYEIAKKVAQSDTPPYNPVLFYGGTGLGKTHILNAIGNHALEKHKKVVLV 175 +Y + ++ Q+D ++ G +G GK + A+ ++ ++ V + Sbjct: 148 EIYRVLARLMQTDLT----LMITGESGTGKELVARALHDYGKRRNGPFVAI 194
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 110 bits (276), Expect = 3e-28 Identities = 58/271 (21%), Positives = 112/271 (41%), Gaps = 21/271 (7%) Query: 180 ELEHKKNQIIKRLNMQKERLKEKLEKLEDPKNLQLEAKELQTQASLLLTYQHLINKHESC 239 L+ K + + K + R +K + L + + + LL + + K S Sbjct: 296 RLKSKSSDLQKIVMNNINRCTKKDKILNNTLKKCEDKDIFKLYGELLTANIYALKKGLSH 355 Query: 240 VVLKDFED---KECAIEIDKSMPLNAFINKKFALSKKKKQKSQFLYLEEENLKEKIAFKE 296 + L ++ I +D++ + + + K K+ + + +E++ + Sbjct: 356 IELANYYSENYDTVKITLDENKTPSQNVQSYYKKYNKLKKSEEAANEQLLQNEEELNYLY 415 Query: 297 NQINYVKEA---------KEESVLEMFM---PVKNSKTKRPMSGYEVLYYKDFKIGLGKN 344 + + + A K+E + ++ + SK + + I +GKN Sbjct: 416 SVLTNINNADNYDEIEEIKKELIETGYIKFKKIYKSKKSKTSKPMHFISKDGIDIYVGKN 475 Query: 345 QKENVKL-LQDARANDLWMHVRDIPGSHLIVFCQKNTPKDEIIMELAKMLIKMQKDVFNS 403 +N L L+ A +D+W H ++IPGSH+IV + P + ++E A + K +S Sbjct: 476 NIQNDYLTLKFANKHDIWFHTKNIPGSHVIVKNIMDIP-ESTLLEAANLAAYYSKSQNSS 534 Query: 404 -YEIDYTQRKFVKIIKGAN---VIYSKYRTI 430 +DYT+ K VK GA VIYS +TI Sbjct: 535 NVPVDYTEVKNVKKPNGAKPGMVIYSTNQTI 565 Score = 34.5 bits (79), Expect = 8e-04 Identities = 21/91 (23%), Positives = 47/91 (51%), Gaps = 3/91 (3%) Query: 46 NTPYIGLSKKPPESVLKNTLALDFCLNKFTKNAKILQANIIDNDRILEIT-GTKDLAYKS 104 N P I L+ + +K + L K+ NAKI+ + I+ DRI+ I + D + Sbjct: 55 NYPRIHLTDLTKPNPIKAPMFCMV-LRKYISNAKIVDIHQINQDRIVVIDFESTDELGFN 113 Query: 105 ENFILRLEMIPKKANLMILDK-EKCVIEAFR 134 + L +E++ + +N+ ++ K + ++++ + Sbjct: 114 SIYSLIIEIMGRHSNMTLIRKRDNIIMDSIK 144
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 40.6 bits (95), Expect = 9e-06 Identities = 24/116 (20%), Positives = 45/116 (38%), Gaps = 20/116 (17%) Query: 134 LEHLEEVELSKSNILLIGPTGSGKTLMAQTLAKHLD------IPI---AISDATSLTEAG 184 L + + +++ G +G+GK L+A+ L + + I AI L E+ Sbjct: 150 YRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPR--DLIESE 207 Query: 185 YVGEDVENILTRLLQASDWNVQKAQKGIVFIDEIDKIS--------RLSENRSITR 232 G + T S ++A+ G +F+DEI + R+ + T Sbjct: 208 LFGH-EKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTT 262
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 473 bits (1219), Expect = e-171 Identities = 178/347 (51%), Positives = 248/347 (71%), Gaps = 2/347 (0%) Query: 2 IFSKLIGLFSHDIAIDLGTANTIVLVKGQGIIINEPSIVAVRMGLFDSKAYDILAVGSEA 61 + K G+FS+D++IDLGTANT++ VKGQGI++NEPS+VA+R S + AVG +A Sbjct: 1 MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKS-VAAVGHDA 59 Query: 62 KEMLGKTPNSIRAIRPMKDGVIADYDITAKMIRYFIEKAHKRKTW-IRPRIMVCVPYGLT 120 K+MLG+TP +I AIRPMKDGVIAD+ +T KM+++FI++ H PR++VCVP G T Sbjct: 60 KQMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGAT 119 Query: 121 SVERNAVKESALSAGAREVFLIEEPMAAAIGAGLPVKEPQGSLIVDIGGGTTEIGVISLG 180 VER A++ESA AGAREVFLIEEPMAAAIGAGLPV E GS++VDIGGGTTE+ VISL Sbjct: 120 QVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLN 179 Query: 181 GLVISKSIRVAGDKLDQSIVEYIRKKFNLLIGERTGEEVKIEIGCAIKLDPPLTMEVSGR 240 G+V S S+R+ GD+ D++I+ Y+R+ + LIGE T E +K EIG A D +EV GR Sbjct: 180 GVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGR 239 Query: 241 DQVSGLLHTIELSSDDVFEAIKDQVREISSALRSVLEEVKPDLAKDIVQNGVVLTGGGAL 300 + G+ L+S+++ EA+++ + I SA+ LE+ P+LA DI + G+VLTGGGAL Sbjct: 240 NLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGAL 299 Query: 301 IKGLDKYLSDMVKLPVYVGDEPLLAVAKGTGEAIQDLDLLSRVGFSE 347 ++ LD+ L + +PV V ++PL VA+G G+A++ +D+ FSE Sbjct: 300 LRNLDRLLMEETGIPVVVAEDPLTCVARGGGKALEMIDMHGGDLFSE 346
>PRPHPHLPASEC#Prokaryotic zinc-dependent phospholipase C signature. Length = 398 Score = 32.3 bits (73), Expect = 0.010 Identities = 13/32 (40%), Positives = 19/32 (59%), Gaps = 2/32 (6%) Query: 903 GITYADYEHKADAYKLFKDKIFNPKNDPNFKI 934 G TY DY+ +AY L++D ++P D NF Sbjct: 79 GSTYPDYDK--NAYDLYQDHFWDPDTDNNFSK 108
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 90.7 bits (225), Expect = 2e-23 Identities = 37/118 (31%), Positives = 56/118 (47%), Gaps = 2/118 (1%) Query: 1 MQK-KIFLLEDDYLLSESVKEFLEHLGYEVFCAFNGKEAYERLSVERFNLLLLDVQVPEM 59 M I + +DD + + + L GY+V N + ++ +L++ DV +P+ Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 60 NSLELFRRIKNDFLISTPVIFITALQDNATLKNAFNLGASDYLKKPFDLDELEARIKR 117 N+ +L RIK PV+ ++A T A GA DYL KPFDL EL I R Sbjct: 61 NAFDLLPRIKKA-RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 639 bits (1650), Expect = 0.0 Identities = 178/671 (26%), Positives = 304/671 (45%), Gaps = 66/671 (9%) Query: 9 RIRNIGIAAHIDAGKTTTSERILFYTGVSHKIGEVHDGAATMDWMEQEKERGITITSAAT 68 +I NIG+ AH+DAGKTT +E +L+ +G ++G V G D E++RGITI + T Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 69 TCFWKDHQINLIDTPGHVDFTIEVERSMRVLDGAVSVFCSVGGVQPQSETVWRQANKYGV 128 + W++ ++N+IDTPGH+DF EV RS+ VLDGA+ + + GVQ Q+ ++ K G+ Sbjct: 62 SFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGI 121 Query: 129 PRIVFVNKMDRIGANFYNVENQIKLRLKANPVPINIPIGAEDTFIGVIDLVQMKAIVWNN 188 P I F+NK+D+ G + V IK +L A V Sbjct: 122 PTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVI--------------------------- 154 Query: 189 ETMGAKYDVEEIPSDLLEKAKQYREKLVEAVAEQDEALMEKYLGGEELSVEEIKKGIKTG 248 K VE P+ + + + + V E ++ L+EKY+ G+ L E+++ Sbjct: 155 -----KQKVELYPNMCVTNFTESEQ--WDTVIEGNDDLLEKYMSGKSLEALELEQEESIR 207 Query: 249 CLNMSLVPMLCGSSFKNKGVQTLLDAVIDYLPAPTEVVDIKGIDPKTEEEVFVKSSDDGE 308 N SL P+ GS+ N G+ L++ + + + T E Sbjct: 208 FHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSSTH-------------------RGQSE 248 Query: 309 FAGLAFKIMTDPFVGQLTFVRVYRGKLESGSYVYNSTKDKKERVGRLLKMHSNKREDIKE 368 G FKI +L ++R+Y G L V S K+K ++ + + + I + Sbjct: 249 LCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKI-KITEMYTSINGELCKIDK 307 Query: 369 VYAGEICAFVG----LKDTLTGDTLCDEKNAVVLERMEFPEPVIHIAVEPKTKADQEKMG 424 Y+GEI L L GDT + ER+E P P++ VEP +E + Sbjct: 308 AYSGEIVILQNEFLKLNSVL-GDTKLLPQR----ERIENPLPLLQTTVEPSKPQQREMLL 362 Query: 425 VALGKLAEEDPSFRVMTQEETGQTLIGGMGELHLEIIVDRLKREFKVEAEIGQPQVAFRE 484 AL ++++ DP R T + ++ +G++ +E+ L+ ++ VE EI +P V + E Sbjct: 363 DALLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIKEPTVIYME 422 Query: 485 TIRSSVSKEHKYAKQSGGRGQYGHVFIKLEPKEPGSGYEFVNEISGGVIPKEYIPAVDKG 544 R E+ + + + + + P GSG ++ + +S G + + + AV +G Sbjct: 423 --RPLKKAEYTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSFQNAVMEG 480 Query: 545 IQEAMQNGVLAGYPVVDFKVTLYDGSYHDVDSSEMAFKIAGSMAFKEASRAANPVLLEPM 604 I+ + G L G+ V D K+ G Y+ S+ F++ + ++ + A LLEP Sbjct: 481 IRYGCEQG-LYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPY 539 Query: 605 MKVEVEVPEEYMGDVIGDLNRRRGQINSMDDRLGLKIVNAFVPLVEMFGYSTDLRSATQG 664 + ++ P+EY+ D + I + I++ +P + Y +DL T G Sbjct: 540 LSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKNNEVILSGEIPARCIQEYRSDLTFFTNG 599 Query: 665 RGTYSMEFDHY 675 R E Y Sbjct: 600 RSVCLTELKGY 610
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 28.9 bits (64), Expect = 0.048 Identities = 20/58 (34%), Positives = 31/58 (53%), Gaps = 3/58 (5%) Query: 180 EALRIVDKLEKIGLNGVEEELKKECDLKPNTIKELLEMVQIKQNDL--SHAEFFEKIA 235 + ++KLEK G + E LKKE ++ + I L +K + L HA+ F+KIA Sbjct: 263 DMFEYMNKLEKGGFEKISESLKKE-GVEKDRIDVLKGEKALKASGLVPEHADAFKKIA 319
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 32.3 bits (73), Expect = 0.004 Identities = 32/146 (21%), Positives = 50/146 (34%), Gaps = 21/146 (14%) Query: 96 DDQSKKEVAETQKEAENARDRANKSGIELE-QEKQKTSNIETNNQIKVEQE---KQKTSN 151 + EVA++ E + + K +E +EK K +T KV + KQ+ S Sbjct: 1078 ANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSE 1137 Query: 152 IETNNQIKVEQEKQKTSNI-----ETNNQIKVEQEKQKTS-----------NIETNNQIK 195 Q + +E T NI +TN EQ ++TS + T N + Sbjct: 1138 -TVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVV 1196 Query: 196 VEQEQQKTEQEQQKTEQEKQKTIKTQ 221 E Q E K + Sbjct: 1197 ENPENTTPATTQPTVNSESSNKPKNR 1222
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 49.8 bits (119), Expect = 9e-09 Identities = 54/292 (18%), Positives = 102/292 (34%), Gaps = 22/292 (7%) Query: 35 ALLSDIAKSFEMESASVGLMITLYAWLVSLGSLPLMLFSAKIERKRLLLFLFALFILSHI 94 LL D+ S +A G+++ LYA + + L S + R+ +LL A + + Sbjct: 30 GLLRDLVHS-NDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYA 88 Query: 95 LSALAWNFWVLLISR--AGIALAHSVFWSITASLVIRVAPIGRKQQALGLLALGSSLAMI 152 + A A WVL I R AGI A ++ + + + + + G ++ M+ Sbjct: 89 IMATAPFLWVLYIGRIVAGITGATG---AVAGAYIADITDGDERARHFGFMSACFGFGMV 145 Query: 153 LGLPLGRIIGQILDWRSTFGVIGGVATLIALLMYKLLPP----------LPSKNAGTLSS 202 G LG ++G + F + L L LLP + N Sbjct: 146 AGPVLGGLMGGF-SPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFR 204 Query: 203 LPVLVKRPLLMGIYLLVIMVISGHFTTYSYIEPFIIQISQFSPDITTLMLFVFGLAG-VV 261 + + ++ ++ I F + + L FG+ + Sbjct: 205 WARGMTVVAALMAVFFIMQLVGQVPAALWVI--FGEDRFHWDATTIGISLAAFGILHSLA 262 Query: 262 GSFLFGRLYAK-NSRKFIAFAMVLVICPQLLLFVFKNSEWVVFLQIFLWGIG 312 + + G + A+ R+ + M+ +L F W+ F + L G Sbjct: 263 QAMITGPVAARLGERRALMLGMIADGT-GYILLAFATRGWMAFPIMVLLASG 313
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 28.5 bits (63), Expect = 0.015 Identities = 20/52 (38%), Positives = 30/52 (57%), Gaps = 5/52 (9%) Query: 60 GELVPLEIVVETILSAIKSSDKGIILIDGYPRSVEQMQALDKELSAQNEVVL 111 G+L+ I VE LS I + D L+ P++ E++ ALDKEL A+ + L Sbjct: 127 GKLIAYPIAVEA-LSLIYNKD----LLPNPPKTWEEIPALDKELKAKGKSAL 173
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 54.8 bits (132), Expect = 1e-10 Identities = 25/121 (20%), Positives = 52/121 (42%), Gaps = 7/121 (5%) Query: 194 ILIAEDSLSALKTLEKIVQTLELRYLAFPNGKELLDYLYEKEHYQQVGVVITDLEMPVIS 253 IL+A+D + L + + N L ++ +V+TD+ MP + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAA----GDGDLVVTDVVMPDEN 61 Query: 254 GFEVLKIIKADSRTEHLPVIINSSMSSDSNRQLAQSLEADGFVVKS-NILEIHEMLRKTL 312 F++L IK LPV++ S+ ++ A A ++ K ++ E+ ++ + L Sbjct: 62 AFDLLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119 Query: 313 S 313 + Sbjct: 120 A 120
>LCRVANTIGEN#Low calcium response V antigen signature. Length = 326 Score = 31.2 bits (70), Expect = 6e-04 Identities = 16/33 (48%), Positives = 20/33 (60%) Query: 16 KRKKLLTELAELEAEIKVSSERKSSFNISLSPS 48 R KL ELAEL AE+K+ S ++ N LS S Sbjct: 149 ARSKLREELAELTAELKIYSVIQAEINKHLSSS 181
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 274 bits (701), Expect = 3e-76 Identities = 106/407 (26%), Positives = 189/407 (46%), Gaps = 15/407 (3%) Query: 2785 SAGLNAIES-AGNNSLMWLNALFVAKGGNPLFAPYYLQDNSTEHIVTLMKDITSTLGMLS 2843 S ++ + + +G L L + + +A + S I + T+TL ++ Sbjct: 894 SNDIDTLYANSGAQGRDLLQTLLI-DSHDAGYARTMIDATSANEITKQLNTATTTLNNIA 952 Query: 2844 KSNLKNNSTDVLQLNTYTQQMGRLAKLSSFASFDSTDFSERLSSLKNQRFADAIPNAMDV 2903 K + L L+ RL LS + F++RL +LK+QRFA + +A +V Sbjct: 953 SLEHKTSGLQTLSLSNAMILNSRLVNLSRRHTNHIDSFAKRLQALKDQRFAS-LESAAEV 1011 Query: 2904 ILKYSQRDKLKNNLWATGVGGVSFVENGTGTLYGVNVGYDRFIKG---VIVGGYAAYGYS 2960 + +++ + + N+WA +GG S G +LYG + G D ++ G IVGG+ +YGYS Sbjct: 1012 LYQFAPKYEKPTNVWANAIGGTSLNSGGNASLYGTSAGVDAYLNGEVEAIVGGFGSYGYS 1071 Query: 2961 GFYER--ITSSKSDNVDVGLYARAFIKKSELTFSVNETWGANKTQISSNDTLLSMINQSY 3018 F + +S ++N + G+Y+R F + E F G++++ ++ LL +NQSY Sbjct: 1072 SFSNQANSLNSGANNTNFGVYSRIFANQHEFDFEAQGALGSDQSSLNFKSALLRDLNQSY 1131 Query: 3019 QYSTWTTNARVNYGYDFMFKNKSVIVKPQIGLRYYYIGMTGLDGVMNNALYNQFKANADP 3078 Y ++ R +YGYDF F ++++KP +G+ Y ++G T + Sbjct: 1132 NYLAYSAATRASYGYDFAFFRNALVLKPSVGVSYNHLGSTNFKS----NSNQKVALKNGA 1187 Query: 3079 SKKSVLMIDFAFENRHYFNKNSYFYAIGGIGRDLLVRSMGDKLVRFIGDNILSYRKGELY 3138 S + + E R+Y+ SYFY G+ ++ + V + + R Sbjct: 1188 SSQHLFNASANVEARYYYGDTSYFYMNAGVLQEFANFGSSNA-VSLNTFKVNATRNP--L 1244 Query: 3139 NTFANITTGGEIRLFKSFYVNAGVGARFGLDYKMINITGNIGMRLAF 3185 NT A + GGE++L K ++N G L + + N+GMR +F Sbjct: 1245 NTHARVMMGGELKLAKEVFLNLGFVYLHNLISNIGHFASNLGMRYSF 1291 Score = 33.1 bits (75), Expect = 0.027 Identities = 49/302 (16%), Positives = 88/302 (29%), Gaps = 51/302 (16%) Query: 210 NTDFGNQTPNGGFNVMGRKITYNGGIVNGGNFGFDNVDSNGTTTISGVTFNNNGALTYKG 269 + + G + + N G + D TT + + + Sbjct: 300 AGIIASNKTHIGTLDLWQSAGLNIIAPPEGGYKDKPNDKPSNTTQNNAKNDKQESSQNNS 359 Query: 270 GNGI-----------------------GGSITFTNSNINHYKLNLNANGVTFNNSALGSM 306 + GG T N N ++N NA+G S+ Sbjct: 360 NTQVINPPNSAQKTEIQPTQVIDGPFAGGKNTVVNIN----RINTNADGTIRVGGFKASL 415 Query: 307 PNGNANTVGNAYILNASNITFN----------NLTFNG--------GWFVFDRSNASVHF 348 A+ +N SN N+T +G G + S+A+ F Sbjct: 416 TTNAAHLHIGKGGINLSNQASGRSLLVENLTGNITVDGPLRVNNQVGGYALAGSSANFEF 475 Query: 349 QGTTTINNPTSPFVNMSAKVTINPNAVFNIQNYTPTIGSAYTLFSMKNGNITYNDVSNLW 408 + T N T+ F N + V I + F+ + ++ V+N Sbjct: 476 KAGTDTKNGTATFNNDISLGRFVNLKVDAHTANFKGIDTGNGGFNT----LDFSGVTNKV 531 Query: 409 NIIRLKNTQATKDNSKNATSNNNTHTYYVTYNLGGTLYNFRQIFSPDSIVLQSVYYGANN 468 NI +L A+ + + + N ++G + I S I + G + Sbjct: 532 NINKL--ITASTNVAVKNFNINELVVKTNGVSVGEYTHFSEDIGSQSRINTVRLETGTRS 589 Query: 469 IY 470 IY Sbjct: 590 IY 591 Score = 32.3 bits (73), Expect = 0.043 Identities = 14/100 (14%), Positives = 31/100 (31%), Gaps = 5/100 (5%) Query: 699 SYTFNGTNNTFNEDKFNGGSFNFNHAEQTDAFNNNSFNGGSFSFNAKQVDFSGNSFNGGV 758 SY+ T+ E FN + ++A Q +N + G+ + + + G Sbjct: 272 SYSTINTSKVTGEVNFNHLTVGDHNAAQAGIIASNKTHIGTLDLW-QSAGLNIIAPPEGG 330 Query: 759 FDF---NNTPKVSFTDDTFNANNQFKING-AQTTFTFNKG 794 + + + + + + N Q N Sbjct: 331 YKDKPNDKPSNTTQNNAKNDKQESSQNNSNTQVINPPNSA 370
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 901 bits (2331), Expect = 0.0 Identities = 284/1038 (27%), Positives = 515/1038 (49%), Gaps = 40/1038 (3%) Query: 1 MYKTAINRPITTLMFALAIVFFGTMGFKKLSVALFPKIDLPTVVVTTTYPGASAEIIESK 60 M I RPI + A+ ++ G + +L VA +P I P V V+ YPGA A+ ++ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTDKIEEAVMGIDGIKKVTSTSSKNVSIVV-IEFELEKPNEEALNDVVNKISSVR-FDDS 118 VT IE+ + GID + ++STS S+ + + F+ + A V NK+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 119 NIKKPSINKFDTDSQAIISLFVSSSSVPAT--TLNDYAKKTIKPMLQKIDGVGGVQLNGF 176 +++ I+ + S ++ S + T ++DY +K L +++GVG VQL G Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG- 179 Query: 177 RERQIRIYADPTLMNKYNLTYADLFSTLKAENVEIDGGRIVNS------QRELSILVNAN 230 + +RI+ D L+NKY LT D+ + LK +N +I G++ + Q SI+ Sbjct: 180 AQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 231 SYSVADVEKIQV-----GNHVRLGDIAKIEIGLEEDNTFASFKDKPGVILEIQKIAGANE 285 + + K+ + G+ VRL D+A++E+G E N A KP L I+ GAN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 286 IEIVDRVYEALKHIQAISP-NYEIRPFLDTTGYIRTSIEDVKFDLVLGAVLAVLVVFAFL 344 ++ + L +Q P ++ DTT +++ SI +V L +L LV++ FL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 345 RNGTITLVSAISIPISVMGTFALIQWMGFSLNMLTMVALTLAIGIIIDDAIVVIENIHK- 403 +N TL+ I++P+ ++GTFA++ G+S+N LTM + LAIG+++DDAIVV+EN+ + Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 404 KLEMGMNKRKASYEGVREIGFALVAISAMLLSVFVPIGNMKGIIGRFFQSFGITVALAIA 463 +E + ++A+ + + +I ALV I+ +L +VF+P+ G G ++ F IT+ A+A Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 464 LSYVVVVTIIPMISSVVVNPRHS-------RFYVWSEPFFKALESRYTKLLQWVLNHKLI 516 LS +V + + P + + ++ P + F+ W F + YT + +L Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 517 IFIAVVLVFVGSLFVASKLGMEFMLKEDRGRFLVWLKAKPGVSIDY----MTQKSKIFQK 572 + L+ G + + +L F+ +ED+G FL ++ G + + + Q + + K Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 573 AIEKHAEVEFTTLQVGY-GTTQNPFKAKIFVQLKPLKERKKEHELGQFELMSALRKELKS 631 + + E FT + G QN FV LKP +ER E ++ + EL Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNA--GMAFVSLKPWEERNG-DENSAEAVIHRAKMELGK 656 Query: 632 MPEAKGLENINLSEVSLIGGGGDSSPFQTFVFSHSQEAVDKSVANLKKFLLESPELKGKI 691 + + + N+ + G ++ F + + D + L + + + Sbjct: 657 IRDGF-VIPFNMPAIV---ELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASL 712 Query: 692 EGYHTSTSESQPQLQLKILRQNANKYGVSAQTIGSVVSSAFSGTSQASVFKEDGKEYDMI 751 + E Q +L++ ++ A GVS I +S+A G + + F + G+ + Sbjct: 713 VSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGG-TYVNDFIDRGRVKKLY 771 Query: 752 IRVPDNKRVSVEDIKRLQVRNKYDKLMFLDALVEITETKSPSSISRYNRQRSVTVLAQPK 811 ++ R+ ED+ +L VR+ +++ A + RYN S+ + + Sbjct: 772 VQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAA 831 Query: 812 AGISLGEILTQVSKNTKEWLVEGANYRFTGEADNAKETNGEFLIALATAFVLIYMILAAL 871 G S G+ + + +N L G Y +TG + + + + +A +FV++++ LAAL Sbjct: 832 PGTSSGDAMALM-ENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAAL 890 Query: 872 YESILEPFIIMVTMPLSFSGAFFALGLVHQPLSMFSMIGLILLIGMVGKNATLLIDVANE 931 YES P +M+ +PL G A L +Q ++ M+GL+ IG+ KNA L+++ A + Sbjct: 891 YESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKD 950 Query: 932 -ERKKGLNIQEAILFAGKTRLRPILMTTIAMVCGMLPLALASGDGAAMKSPIGIAMSGGL 990 K+G + EA L A + RLRPILMT++A + G+LPLA+++G G+ ++ +GI + GG+ Sbjct: 951 LMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGM 1010 Query: 991 MISMVLSLLIVPVFYRLL 1008 + + +L++ VPVF+ ++ Sbjct: 1011 VSATLLAIFFVPVFFVVI 1028
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 51.0 bits (122), Expect = 1e-09 Identities = 22/69 (31%), Positives = 34/69 (49%) Query: 40 STGIVDSIKVTEGSVVKKGDVLLLLYNQDKQAQSDSTEQQLIFAKKQYQRYSKIGGAVDK 99 IV I V EG V+KGDVLL L +A + T+ L+ A+ + RY + +++ Sbjct: 103 ENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIEL 162 Query: 100 NTLESYEFN 108 N L + Sbjct: 163 NKLPELKLP 171 Score = 31.7 bits (72), Expect = 0.003 Identities = 21/152 (13%), Positives = 48/152 (31%), Gaps = 25/152 (16%) Query: 70 QAQSDSTEQQLIFAKKQYQR--YSKIGGAVDKNTLESYEFNYRRLESDYAYSIALLNKTI 127 +++ S +++ + ++ K+ D + + E ++ Sbjct: 279 ESEILSAKEEYQLVTQLFKNEILDKLRQTTDN--IGLLTLELAKNEER-------QQASV 329 Query: 128 LRAPFDGVIASKNIQVGEGVSANNTVLLRLVSHARKLVIE--FDSKYINAVKVG------ 179 +RAP + + GV L+ +V L + +K I + VG Sbjct: 330 IRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIK 389 Query: 180 -DTYTYSIDGDSNQHEAKITKIYP--TVDENT 208 + + Y+ G K+ I D+ Sbjct: 390 VEAFPYTRYGYL---VGKVKNINLDAIEDQRL 418
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.7 bits (66), Expect = 0.009 Identities = 13/95 (13%), Positives = 25/95 (26%), Gaps = 20/95 (21%) Query: 60 ILENDDETNLKKIAYAEFSKLAECVRPSGFYNQKAKRLINLSENILKDFQSFENFKQEVT 119 L + +A+ E + VR + +KA E+ Sbjct: 458 ALRSAPALA-GCVAFDELREQPVAVRAFPW--RKAPGP-------------LEDADVLRL 501 Query: 120 REWLLDQKGIGKESADAILCYVCAKEVMVVDKYSY 154 +++ G G+ SA + D Sbjct: 502 ADYVETTYGTGEASAQTTEQAINV----AADMNRV 532
>FLAGELLIN#Flagellin signature. Length = 507 Score = 245 bits (627), Expect = 2e-77 Identities = 126/518 (24%), Positives = 209/518 (40%), Gaps = 22/518 (4%) Query: 2 AFRVNTNINAMNAHVQSALTQNALKTSLERLSSGLRINKAADDASGMTVADSLRSQANSL 61 A +NTN ++ +Q++L +++ERLSSGLRIN A DDA+G +A+ S L Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 GQAIANTNDGMGIIQVADKAMDEQLKILDTVKVKATQAAQDGQTTESRKAIQSDIVRLIQ 121 QA N NDG+ I Q + A++E L V+ + QA + K+IQ +I + ++ Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 GLDNIGNTTTYNGQALLSGQFTNKEFQVGAYSNQSIKASIGSTTSDKIGQVRI-ATGALI 180 +D + N T +NG +LS + QVGA ++I + +G G Sbjct: 121 EIDRVSNQTQFNGVKVLSQDN-QMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKE 179 Query: 181 TASGDISLTFKQVDGVNDVTLESVKISSSAGTGIGVLAEVINKNSNQTGVKAYASVITTS 240 GD+ +FK V G + + + K +G V ++ V A +TT Sbjct: 180 ATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTD 239 Query: 241 DVAVQSGSLSNLTLNGIHLGNIADIKKNDSDGRLVAAINAVTSETGVEAYTDQNGRLNLR 300 D N + K A A+ + + + + Sbjct: 240 DAE-----------NNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTID 288 Query: 301 SLDGRGIEIKTDSVSNGPSALTMVNGGQDLTKGSTNYGRLSLTRLDAKSINV------VS 354 + G K + NG V S + +N + Sbjct: 289 TKTGNDGNGKVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKT 348 Query: 355 ASDSQHLGFTAIGFGESQVAETTVNLRDVTGNFNANVKSASGANYNAVIASGNQSL---G 411 ++S L ++ TVN + T N + + +G + S Sbjct: 349 KNESAKLSDLEANNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINE 408 Query: 412 AGVTTLRGAMVVIDIAESAMKMLDKVRSDLGSVQNQMISTVNNISITQVNVKAAESQIRD 471 + + +SA+ +D VRS LG++QN+ S + N+ T N+ +A S+I D Sbjct: 409 DAAAAKKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIED 468 Query: 472 VDFAEESANFNKNNILAQSGSYAMSQANTVQQNILRLL 509 D+A E +N +K IL Q+G+ ++QAN V QN+L LL Sbjct: 469 ADYATEVSNMSKAQILQQAGTSVLAQANQVPQNVLSLL 506
>OMS28PORIN#OMS28 porin signature. Length = 257 Score = 29.4 bits (65), Expect = 0.009 Identities = 26/109 (23%), Positives = 52/109 (47%), Gaps = 5/109 (4%) Query: 27 NQTTELHHKNPYELLVATILSAQCTDARVNKITPKLFEKYPSVKDLALASLE--EVKEII 84 N+ E+ K E A ++ + T +I + K P+ K+L L E +V+++ Sbjct: 132 NKVVEMSKKAVQETQKAVSVAGEATFLIEKQI---MLNKSPNNKELELTKEEFAKVEQVK 188 Query: 85 KSVSYSNNKSKHLISMAQKVVRDFKGVIPSTQKELMSLDGVGQKTANVV 133 +++ S + AQKV+ G+ PS + ++++ V + +NVV Sbjct: 189 ETLMASERALDETVQEAQKVLNMVNGLNPSNKDQVLAKKDVAKAISNVV 237
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 99 bits (249), Expect = 2e-30 Identities = 25/77 (32%), Positives = 47/77 (61%) Query: 34 LICDYKNLLDMEIVFSAELGSTQIPLLQILRFEKGSVIDLQKPAGESVDTFVNGRVIGKG 93 + D ++D+ + + ELG T++ + ++LR +GSV+ L AGE +D +NG +I +G Sbjct: 50 AMQDIDLIMDIPVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQG 109 Query: 94 EVMVFERNLAIRLNEIL 110 EV+V +R+ +I+ Sbjct: 110 EVVVVADKYGVRITDII 126
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 46.9 bits (111), Expect = 3e-08 Identities = 30/208 (14%), Positives = 66/208 (31%), Gaps = 13/208 (6%) Query: 104 PTPPTPPKPIEKPKPKPKPKPEPKKPNHKHKALKKVEKVEEKKVVEEKKEEKVVEQKVEQ 163 P P +PI P P+ + + + E E K+ V+E+ Sbjct: 41 IELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEK---- 96 Query: 164 KKIEEKKPVKKEFDPNQLSFLPKEVAPPRQENNKGLDNQTRRDIDELYGEEFGDLGTAEK 223 + KP K ++ ++V P +N Sbjct: 97 ---PKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSV 153 Query: 224 DFIRNNLRDIGRITQKYLEYPQVAAYLGQDGTNAVEFYLHPNGDISDLKIIIGSEYKMLD 283 +++ +YP A L +G V+F + P+G + +++I+ M + Sbjct: 154 A------SGPRALSRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFE 207 Query: 284 DNTLKTIQIAYKDYPRPKTKTLIRIRVR 311 ++ + +P + ++ I + Sbjct: 208 REVKNAMRRWRYEPGKPGSGIVVNILFK 235
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 30.5 bits (69), Expect = 0.003 Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 4/64 (6%) Query: 88 LQSYSVMLFFNLLLLIDILGFLPFSIYHYFMASLIVSALFCSSLFLSSPLLGMIALVALS 147 L Y F L+L+ +LPFS S +V + +L PLL + AL+A++ Sbjct: 45 LSDYYFEHFSKLMLIPAEQSYLPFSQ----ALSYVVDNVLLEFFYLCFPLLTVAALMAIA 100 Query: 148 SSLL 151 S ++ Sbjct: 101 SHVV 104
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 86.0 bits (213), Expect = 5e-23 Identities = 30/109 (27%), Positives = 57/109 (52%), Gaps = 4/109 (3%) Query: 2 KLLVVDDSSTMRRIIKNTLSRLGYEDVLEAEHGVEAWEKLNANADTKVLITDWNMPEMNG 61 +LV DD + +R ++ LSR GY DV + W + A D +++TD MP+ N Sbjct: 5 TILVADDDAAIRTVLNQALSRAGY-DVRITSNAATLWRWI-AAGDGDLVVTDVVMPDENA 62 Query: 62 LDLVIKVRADERFKEIPIIMITTEGGKAEVITALKAGVNNYIVKPFTPQ 110 DL+ +++ + ++P+++++ + I A + G +Y+ KPF Sbjct: 63 FDLLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLT 109
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 34.4 bits (79), Expect = 0.001 Identities = 26/131 (19%), Positives = 49/131 (37%), Gaps = 28/131 (21%) Query: 157 KKLINAEKPNVRFNDMAGNEEAKEEVVEIVDFLKYPERYANLGAKIPKGVLLVGPPGTGK 216 ++ E + + G A +E+ ++ R +++ G GTGK Sbjct: 124 RRPSKLEDDSQDGMPLVGRSAAMQEIYRVLA------RLMQTDLT----LMITGESGTGK 173 Query: 217 TLLAKAV---AGEAHVPFFSMGGSSF------IEMF-----VGLGASRVRD-LFETAKKQ 261 L+A+A+ + PF ++ ++ E+F GA FE A+ Sbjct: 174 ELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGG 233 Query: 262 APSIIFIDEID 272 +F+DEI Sbjct: 234 T---LFLDEIG 241
>SECYTRNLCASE#Preprotein translocase SecY subunit signature. Length = 437 Score = 31.6 bits (72), Expect = 0.010 Identities = 25/123 (20%), Positives = 47/123 (38%), Gaps = 11/123 (8%) Query: 84 LALAVIFTLFVVYLSMGAMLSPSLLPKSLLTID-NHSNFLNACLQL-IGTLIVMHLGRDF 141 +ALA++ +V + A L + D + + + + GT +VM LG Sbjct: 122 VALAILQGTGLVATARSAPLFGRCSVGGQIVPDQSIFTTITMVICMTAGTCVVMWLGELI 181 Query: 142 YIQGFKALWHRQPNMSSLIAIGTSAALISSLWPLYLVYTNQWSSYGHYYFESVCVILMFV 201 +G MS L+ I +A S+LW + + G F +V + + + Sbjct: 182 TDRGIGN------GMSILMFISIAATFPSALW---AIKKQGTLAGGWIEFGTVIAVGLIM 232 Query: 202 MVG 204 + Sbjct: 233 VAL 235
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 26.2 bits (57), Expect = 0.023 Identities = 19/64 (29%), Positives = 32/64 (50%) Query: 2 RSSHSFLAREHRILERMHEIIQKSMDSLTQRLDNDLKDDDSRILVPIGYIKGLCKVGNMK 61 R++ + A E + E E+I S + L +D D++ S +V I +GL +V N + Sbjct: 629 RNNIAVGADESVVKEAHREVINSSTEGLLLNIDKDIRKILSGYIVEIEDTEGLKEVINDR 688 Query: 62 PDEL 65 D L Sbjct: 689 YDML 692
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 39.9 bits (93), Expect = 2e-05 Identities = 59/311 (18%), Positives = 104/311 (33%), Gaps = 59/311 (18%) Query: 37 APYFAKEFTHTNDPTLALISAFLVFMLGFFMRPLGSLFFGKLGDKKGRKTSMVYSIILMA 96 P A +F T + +AF++ G+ +GKL D+ G K +++ II+ Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSI------GTAVYGKLSDQLGIKRLLLFGIIINC 90 Query: 97 LGSFLLALLPTKEIVGEWAFLFLLLARLLQGFSVGGE------YGVVATYLSELGKNGKK 150 GS + VG F L++AR +QG G VVA Y+ + + Sbjct: 91 FGSVIGF-------VGHSFFSLLIMARFIQG--AGAAAFPALVMVVVARYIPKENRGKAF 141 Query: 151 GFYGSFQYVTLVGGQLLAIFSLFIVENIYTHEQISAFAWRYLFALGGILALLSLFLRNIM 210 G GS + +G + I I+ W YL + I + FL ++ Sbjct: 142 GLIGS---IVAMGEGVGPAIGGMIAHYIH---------WSYLLLIPMITIITVPFLMKLL 189 Query: 211 EETMDSETTSKTTIKEKTQRGSLK---ELLNHKKALIIVFGLTMGGSLCFYTFTVYLKIF 267 ++ E +G +L + + T + IF Sbjct: 190 KK-------------EVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIF 236 Query: 268 LTNSSSFSPK-------ESSFIMLLALSYFIFLQPLCG---MLADKIKRTQMLMVFAIAG 317 + + + ++ M+ L I + G M+ +K L I Sbjct: 237 VKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGS 296 Query: 318 LIVTPVVFYGI 328 +I+ P I Sbjct: 297 VIIFPGTMSVI 307
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 29.5 bits (66), Expect = 0.013 Identities = 10/40 (25%), Positives = 17/40 (42%) Query: 3 NGYYAATGAMAAQFNRLDLISNNLANLNTNGFKRDDAITG 42 + A + A L+ SNN+++ N G+ R I Sbjct: 2 SLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMA 41
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 139 bits (353), Expect = 3e-37 Identities = 99/437 (22%), Positives = 174/437 (39%), Gaps = 85/437 (19%) Query: 9 NIRNFSIIAHIDHGKSTLADCLIAECNAIS---NREMTSQVMDTMDIEKERGITIKAQSV 65 I N ++AH+D GK+TL + L+ AI+ + + + D +E++RGITI+ Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 66 RLNYTLKGEDYVLNLIDTPGHVDFSYEVSRSLCSCEGALLVVDATQGVEAQTIANTYIAL 125 + E+ +N+IDTPGH+DF EV RSL +GA+L++ A GV+AQT + Sbjct: 62 SFQW----ENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALR 117 Query: 126 DNHLEILPVINKIDLPNANVVEVKQDIEDTIGIDCSNANEVSAKARLGIKD--------- 176 + + INKID ++ V QDI++ + + +V + + + Sbjct: 118 KMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDT 177 Query: 177 -------LLEKIITTIPAPSGDFNAPLKALIYD-------------------------SW 204 LLEK ++ + + ++ + Sbjct: 178 VIEGNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNK 237 Query: 205 F--------------------DNYLGALALVRIMDGSINTEQEILVMGTGKKHGVLGLYY 244 F LA +R+ G ++ + + K + +Y Sbjct: 238 FYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKI-KITEMYT 296 Query: 245 PNPLKKIPTKSLECGEIGIV---SLGLKSVTDIAVGDTLTDAKNPTPKPIEGFMPAKPFV 301 + GEI I+ L L SV +GDT P + IE P + Sbjct: 297 SINGELCKIDKAYSGEIVILQNEFLKLNSV----LGDTKLL---PQRERIEN---PLPLL 346 Query: 302 FAGLYPIETDRFEDLREALLKLQLNDCALNFEPESSVALGFGFRVGFLGLLHMEVIKERL 361 + P + + E L +ALL++ +D L + +S+ + FLG + MEV L Sbjct: 347 QTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATH---EIILSFLGKVQMEVTCALL 403 Query: 362 EREFGLNLIATAPTVVY 378 + ++ + + PTV+Y Sbjct: 404 QEKYHVEIEIKEPTVIY 420 Score = 31.0 bits (70), Expect = 0.015 Identities = 15/75 (20%), Positives = 28/75 (37%), Gaps = 2/75 (2%) Query: 405 IKEPFVRATIITPSEFLGNLMQLLNNKRGIQEKMEYLNQSRVMLTYSLPSNEIVMDFYDK 464 + EP++ I P E+L + L + V+L+ +P+ I ++ Sbjct: 535 LLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQ-LKNNEVILSGEIPARCI-QEYRSD 592 Query: 465 LKSCTKGYASFDYEP 479 L T G + E Sbjct: 593 LTFFTNGRSVCLTEL 607
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 37.5 bits (86), Expect = 3e-05 Identities = 46/212 (21%), Positives = 96/212 (45%), Gaps = 17/212 (8%) Query: 43 PNPEEPLEKKAIENDLIDCLLKKTDELSSHLVKLQMQFEKAQEES-KALIENAKNDGYKI 101 P E + E +I+ + L L +LQMQ A E+ +A I + G+K Sbjct: 17 PPQAEFVPIVEPEETIIE---EAEPSLEQQLAQLQMQ---AHEQGYQAGIAEGRQQGHKQ 70 Query: 102 GFKEGEEKMRNELTHSVNEEKNQLLHAISALDEKMKKSEDHLMALE----KELSAIAIDI 157 G++EG + L + E K+Q + + + + + + L AL+ L +A++ Sbjct: 71 GYQEG---LAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRLMQMALEA 127 Query: 158 AKEVILKEVEDNSQKVALALAEELLKNVLDATDIHLKVNPLDYPYLNERLQNASKI---K 214 A++VI + ++ + + + L + L + L+V+P D +++ L + + Sbjct: 128 ARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGATLSLHGWR 187 Query: 215 LESNEAISKGGVMITSSNGSLDGNLMERFKTL 246 L + + GG +++ G LD ++ R++ L Sbjct: 188 LRGDPTLHPGGCKVSADEGDLDASVATRWQEL 219
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 349 bits (896), Expect = e-122 Identities = 122/338 (36%), Positives = 209/338 (61%), Gaps = 4/338 (1%) Query: 8 KQKAQLDELSMSEKIAILLIQVGEDATGEILRHLDIDSITEISKQIVQLNGTDKQIGAAV 67 K+ + L+ +K AILL+ +G + + ++ ++L + I ++ +I +L ++ V Sbjct: 7 KEILDVSALTGKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKLETITSELKDNV 66 Query: 68 LEEFFAIFQSNQYINTGGLEYARELLTRTLGSEEARKVMDKLTKSLQTQKNFAYLGKIKP 127 L EF + + ++I GG++YARELL ++LG+++A +++ L +LQ+ + F ++ + P Sbjct: 67 LLEFKELMMAQEFIQKGGIDYARELLEKSLGTQKAVDIINNLGSALQS-RPFEFVRRADP 125 Query: 128 QQLADFIINEHPQTIALILAHMEAPNAAETLSYFPDEMKAEISIRMANLGEISPQVVKRV 187 + +FI EHPQTIALIL++++ A+ LS P E++ ++ R+A + SP+VV+ V Sbjct: 126 ANILNFIQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVVREV 185 Query: 188 STVLENKLESLTSYK-IEVGGLRAVAEIFNRLGQKSAKTTLARIESVDNKLAGAIKEMMF 246 VLE KL SL+S GG+ V EI N +K+ K + +E D +LA IK+ MF Sbjct: 186 ERVLEKKLASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPELAEEIKKKMF 245 Query: 247 TFEDIVKLDNFAIREILKVADKKDLSLALKTSTQDLTDKFLNNMSSRAAEQFVEEMQYLG 306 FEDIV LD+ +I+ +L+ D ++L+ ALK+ + +K NMS RAA E+M++LG Sbjct: 246 VFEDIVLLDDRSIQRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRAASMLKEDMEFLG 305 Query: 307 AVKIKDVDVAQRKIIEIVQSLQEKG--VIQTGEEEDVI 342 + KDV+ +Q+KI+ +++ L+E+G VI G EEDV+ Sbjct: 306 PTRRKDVEESQQKIVSLIRKLEEQGEIVISRGGEEDVL 343 Score = 30.9 bits (70), Expect = 0.006 Identities = 20/103 (19%), Positives = 41/103 (39%), Gaps = 3/103 (2%) Query: 4 KLTPKQKAQLDELSMSEKIAILLIQVGEDATGEILRHLDIDSITEISKQIVQLNGTDKQI 63 + P + + IA++L + IL L + T ++++I ++ T ++ Sbjct: 122 RADPANILNFIQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEV 181 Query: 64 GAA---VLEEFFAIFQSNQYINTGGLEYARELLTRTLGSEEAR 103 VLE+ A S Y + GG++ E++ E Sbjct: 182 VREVERVLEKKLASLSSEDYTSAGGVDNVVEIINMADRKTEKF 224
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 551 bits (1420), Expect = 0.0 Identities = 179/582 (30%), Positives = 294/582 (50%), Gaps = 66/582 (11%) Query: 11 VDFFIKLNKKQKIALIAAGVLITALLVFLLLYPFKEKDYAQGGYGVLFERLDSSDNALIL 70 +++ +L +I LI AG A++V ++L+ K DY LF L D I+ Sbjct: 13 LEWLNRLRANPRIPLIVAGSAAVAIVVAMVLWA-KTPDYR-----TLFSNLSDQDGGAIV 66 Query: 71 QHLQQNQIPYKILKDD-TILIPKDKVYEERITLASQGIPKTSKVGFEIFDTKDFGATDFD 129 L Q IPY+ I +P DKV+E R+ LA QG+PK VGFE+ D + FG + F Sbjct: 67 AQLTQMNIPYRFANGSGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQFS 126 Query: 130 QNIKLIRAIEGELSRTIESLNPILKANVHIAIPKDSVFVAKEVPPSASVMLKLKPDMKLS 189 + + RA+EGEL+RTIE+L P+ A VH+A+PK S+FV ++ PSASV + L+P L Sbjct: 127 EQVNYQRALEGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLEPGRALD 186 Query: 190 PTQILGIKNLIAAAVPKLTTENVKIVNENGESIGEGDILENSKELALEQLRYKQNFENIL 249 QI + +L+++AV L NV +V+++G + + + + ++L QL++ + E+ + Sbjct: 187 EGQISAVVHLVSSAVAGLPPGNVTLVDQSGHLLTQSNT--SGRDLNDAQLKFANDVESRI 244 Query: 250 ENKIVNILAPIVGGKNKVVARVNAEFDFSQKKSTKETFDPNN-----VVRSEQNLEEKKE 304 + +I IL+PIVG N V A+V A+ DF+ K+ T+E + PN +RS Q ++ Sbjct: 245 QRRIEAILSPIVGNGN-VHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQV 303 Query: 305 GAPKKQVGGVPGVVSN-IGPVQGLKDNKEPEKYEKSQN---------------------- 341 GA GGVPG +SN P P + +QN Sbjct: 304 GAGYP--GGVPGALSNQPAPPNEAPIATPPTNQQNAQNTPQTSTSTNSNSAGPRSTQRNE 361 Query: 342 TTNYEVGKTISEIKGEFGTLVRLNAAVVVDGKYKIALKDGANTLEYEPLSDESLKKINAL 401 T+NYEV +TI K G + RL+ AVVV+ K L DG + PL+ + +K+I L Sbjct: 362 TSNYEVDRTIRHTKMNVGDIERLSVAVVVNYK---TLADG----KPLPLTADQMKQIEDL 414 Query: 402 VKQAIGYNQNRGDDVAVSNFEFNPMAPMLDNATLSEKIMHKTQKVLGSFTPLIKYILVFI 461 ++A+G++ RGD + V N F+ + T E + Q + +++LV + Sbjct: 415 TREAMGFSDKRGDTLNVVNSPFSAVDN-----TGGELPFWQQQSFIDQLLAAGRWLLVLV 469 Query: 462 VLFIFYKKVIVPFSERMLEVVPDEDKEVKSMFEEMDEEEDELNKLGDLRKKVEDQLGLNA 521 V +I ++K + P R +E ++ + E + E L+K L+++ +Q Sbjct: 470 VAWILWRKAVRPQLTRRVEEAKAAQEQAQVRQETEEAVEVRLSKDEQLQQRRANQ----- 524 Query: 522 TFSEEEVRYEIVLEKIRGTLKERPDEIAMLFKLLIKDEISSD 563 + E++ ++IR E D + L+I+ +S+D Sbjct: 525 -----RLGAEVMSQRIR----EMSDNDPRVVALVIRQWMSND 557
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 284 bits (727), Expect = 1e-90 Identities = 68/233 (29%), Positives = 120/233 (51%), Gaps = 9/233 (3%) Query: 5 GSVTLIGFN--GNIMHSLANNVDVGMYARAFLKRNEFTLSANEIYGGNASNINSSNSLLS 62 GS F+ N ++S ANN + G+Y+R F ++EF A G + S++N ++LL Sbjct: 1066 GSYGYSSFSNQANSLNSGANNTNFGVYSRIFANQHEFDFEAQGALGSDQSSLNFKSALLR 1125 Query: 63 VLNQRYSYNTWTTSVNGNYGYDFMFKQKSVVLKPQVGLSYHFIGLSAMKGRMNDAAYKQF 122 LNQ Y+Y ++ + +YGYDF F + ++VLKP VG+SY+ +G + K + ++ Sbjct: 1126 DLNQSYNYLAYSAATRASYGYDFAFFRNALVLKPSVGVSYNHLGSTNFKSN----SNQKV 1181 Query: 123 LMHSNPSNESVLTLNMGLESRKYFGKNSYYFVTARLGRDLLIKSKGNNVVRFVGEDTLLY 182 + + S++ + + +E+R Y+G SY+++ A + ++ +N V Sbjct: 1182 ALKNGASSQHLFNASANVEARYYYGDTSYFYMNAGVLQE-FANFGSSNAVSLNTFKVNAT 1240 Query: 183 RKGEVFNTFASVITGGEMHLWRLMHVNAGVGLKMGLQYQDINITGNVGMRVAF 235 R NT A V+ GGE+ L + + +N G L + N+GMR +F Sbjct: 1241 RNP--LNTHARVMMGGELKLAKEVFLNLGFVYLHNLISNIGHFASNLGMRYSF 1291
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 34.2 bits (78), Expect = 9e-06 Identities = 9/59 (15%), Positives = 18/59 (30%), Gaps = 4/59 (6%) Query: 2 GGAFTFNKDFSATNNTAFNSGNFNFKGASSFNGANFSNTGKITIEKEASFNDTTFNTSI 60 G + + N A G + K + +N +K+ S + + I Sbjct: 310 IGTLDLWQS-AGLNIIAPPEGGYKDKPNDKPSNTTQNNAKN---DKQESSQNNSNTQVI 364 Score = 24.6 bits (53), Expect = 0.025 Identities = 5/33 (15%), Positives = 12/33 (36%), Gaps = 1/33 (3%) Query: 29 ASSFNGANFSNTGKITIEKEA-SFNDTTFNTSI 60 F + +N + I K + ++ S+ Sbjct: 408 VGGFKASLTTNAAHLHIGKGGINLSNQASGRSL 440
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 191 bits (487), Expect = 1e-57 Identities = 65/215 (30%), Positives = 98/215 (45%), Gaps = 19/215 (8%) Query: 47 GYDAGNAAN--YLSSQNYQAISVGSGNETGTYSLSGFTNYVGGDLTINLGNSVV-LDLSD 103 G+D GNAA ++ + + V N GTY+LSG N+ GGDL +N+ + + L + Sbjct: 112 GWDWGNAARHYWVKDGQWNKLEVDMQNAVGTYNLSGLINFTGGDLDVNMQKATLRLGQFN 171 Query: 104 SNSFTSYQGYNQGKDDVSFNVGAINLNGALEVGNRVGSGAGTHTGTATLNLNANK---VN 160 NSFTSY+ V FN I ++ LE+ NRVGSGAG + L L A++ Sbjct: 172 GNSFTSYKDSADRTTRVDFNAKNILIDNFLEINNRVGSGAGRKASSTVLTLQASEGITSR 231 Query: 161 INSNISTFKTSQVNIGNANSVITIGSVSLSGDTCSSLASVGVGANCSTSGPSYSFKGATN 220 N+ IS + + +N+ + NSV +G+V L VG + PSYS + Sbjct: 232 ENAEISLYDGATLNLAS-NSVKLMGNVW-----MGRLQYVG-----AYLAPSYSTINTSK 280 Query: 221 ATNTAFSN--ASGSFTFEENATFSGAKWNGGGIHF 253 T N G + + K + G + Sbjct: 281 VTGEVNFNHLTVGDHNAAQAGIIASNKTHIGTLDL 315
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 39.4 bits (92), Expect = 3e-05 Identities = 44/259 (16%), Positives = 87/259 (33%), Gaps = 60/259 (23%) Query: 118 ISSMLFGIFWRLPK--RLDTKMNLENAHKNELENSFQRYDALGVRFEDIAGVNEVKEELL 175 I + G + LPK L + + E + + + + G + +E+ Sbjct: 91 IKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIY 150 Query: 176 EVIDYLKNPKKYQDLGIFLPKGVLLIGPPGVGKTMIAKALASEARVPFFYESGSAFSQIY 235 V+ L L +++ G G GK ++A+AL + F I Sbjct: 151 RVLARLMQTD--------LT--LMITGESGTGKELVARALHDYGK-----RRNGPFVAIN 195 Query: 236 VGAGAKKV--HELFMHAK---------------RHAPSIIFIDEIDALGKARGGHRSDER 278 + A + + ELF H K + +F+DEI + + Sbjct: 196 MAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDM--------PMDA 247 Query: 279 EATLNQLLTEM------DGFLQNDEVVVIGATNQMEVMD-EALLRSKRFDRRIF------ 325 + L ++L + +V ++ ATN+ D + + F ++ Sbjct: 248 QTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNK----DLKQSINQGLFREDLYYRLNVV 303 Query: 326 -ISLPDLSERQSILEKLLE 343 + LP L +R + L+ Sbjct: 304 PLRLPPLRDRAEDIPDLVR 322
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.7 bits (72), Expect = 0.008 Identities = 16/50 (32%), Positives = 21/50 (42%), Gaps = 7/50 (14%) Query: 30 VAIVGESGSGKSSIANIIMRLNPR----FKPHNGEVLFETTNLLQESEEF 75 + I GESG+GK +A + R F N + L ESE F Sbjct: 163 LMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRD---LIESELF 209
>SECA#SecA protein signature. Length = 901 Score = 29.8 bits (67), Expect = 0.030 Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 2/63 (3%) Query: 261 IVFTRTKKEADELHQFLASKNYKSTALHGDMDQRDRRASIMAFKKNDADVLVATDVASRG 320 +V T + ++++ + L K L+ + A+I+A A V +AT++A RG Sbjct: 453 LVGTISIEKSELVSNELTKAGIKHNVLNAKFHANE--AAIVAQAGYPAAVTIATNMAGRG 510 Query: 321 LDI 323 DI Sbjct: 511 TDI 513
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 361 bits (929), Expect = e-126 Identities = 119/345 (34%), Positives = 191/345 (55%), Gaps = 26/345 (7%) Query: 19 AEKIGDIASVVGVRDNQLIGYGLVIGLNGTGDK-SGSKFTMQSISNMLESVNVKISADDI 77 +I DIAS+ RDNQLIGYGLV+GL GTGD S FT QS+ ML+++ + Sbjct: 28 TSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFTEQSMRAMLQNLGITTQGGQS 87 Query: 78 KSKNVAAVMITASLPPFARQGDKIDVQISSIGDAKSIQGGTLVMTPLNAVDGNIYALAQG 137 +KN+AAVM+TA+LPPFA G ++DV +SS+GDA S++GG L+MT L+ DG IYA+AQG Sbjct: 88 NAKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRGGNLIMTSLSGADGQIYAVAQG 147 Query: 138 AITSGN-----------SNNLLSANIINGATIEREVSYDLFHKNAMVLSLKNPNFKNAIQ 186 A+ SA + NGA IERE+ +VL L+NP+F A++ Sbjct: 148 ALIVNGFSAQGDAATLTQGVTTSARVPNGAIIERELPSKFKDSVNLVLQLRNPDFSTAVR 207 Query: 187 VQNTLNKV----FGNKVAIALDPKTIQITRPERFSMVEFLALVQEIPINYSAKNKIIVDE 242 V + +N +G+ +A D + I + +P + +A ++ + + K++++E Sbjct: 208 VADVVNAFARARYGDPIAEPRDSQEIAVQKPRVADLTRLMAEIENLTVETDTPAKVVINE 267 Query: 243 KSGTIVSGVDIMVHPIVVTSQDITLKITKDPLDN--------SKNAQDLDNNMSLDTAHN 294 ++GTIV G D+ + + V+ +T+++T+ P Q + M++ Sbjct: 268 RTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQPAPFSRGQTAVQPQTDIMAMQEGSK 327 Query: 295 TLSSNGKNITIAGVVKALQKIGVSAKGMVSILQALKKSGAISAEM 339 G ++ +V L IG+ A G+++ILQ +K +GA+ AE+ Sbjct: 328 VAIVEGPDLR--TLVAGLNSIGLKADGIIAILQGIKSAGALQAEL 370
>PF06580#Sensor histidine kinase Length = 349 Score = 30.2 bits (68), Expect = 0.015 Identities = 10/71 (14%), Positives = 25/71 (35%), Gaps = 13/71 (18%) Query: 281 IVLQNFLYNAIDAIEALEESEQ-GQVKIEAFIQNEFIVFTIIDNGKEVENKSALFEPFET 339 +++Q + N I + + Q G++ ++ N + + + G + Sbjct: 258 MLVQTLVENGI--KHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTK------- 308 Query: 340 TKLKGNGLGLA 350 + G GL Sbjct: 309 ---ESTGTGLQ 316
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 149 bits (377), Expect = 3e-49 Identities = 40/140 (28%), Positives = 75/140 (53%), Gaps = 1/140 (0%) Query: 5 EILKHLQADAIVLFMKVHNFHWNVKGTDFFNVHKATEEIYEEFADMFDDLAERIVQLGHH 64 L ++ +L+ K+H FHW VKG FF +H+ EE+Y+ A+ D +AER++ +G Sbjct: 15 NSLNTQLSNWFLLYSKLHRFHWYVKGPHFFTLHEKFEELYDHAAETVDTIAERLLAIGGQ 74 Query: 65 PLVTLTEALKLTRIKEETKTSFHSKDIFKEILEDYKHLEKEFKELSNTAEKEGDKVTVTY 124 P+ T+ E + I + + + ++ + ++ DYK + E K + AE+ D T Sbjct: 75 PVATVKEYTEHASITDGGNET-SASEMVQALVNDYKQISSESKFVIGLAEENQDNATADL 133 Query: 125 ADDQLAKLQKSIWMLQAHLA 144 + +++K +WML ++L Sbjct: 134 FVGLIEEVEKQVWMLSSYLG 153
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 50.6 bits (121), Expect = 3e-09 Identities = 51/346 (14%), Positives = 106/346 (30%), Gaps = 54/346 (15%) Query: 5 VLITGAYGMVGQNTALYFKKNKPDV-----------TLLTPKKNELY-----------LL 42 L+TGA G +G + + + V L + EL L Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDLA 62 Query: 43 DKDNVQAYLKEYKPTGIIHCAGRVGGIVANMSDLSTYMVENLLMGLYLFSSALDLGVKKA 102 D++ + + R + ++ + Y NL L + ++ Sbjct: 63 DREGMTDLFASGHFERVFISPHR-LAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 103 INLASSCAYPKFAPNPLKESDLLNGSLEPTNEGYALAKLSVMKYCEYVSTEKGVFYKTLV 162 + +SS Y P D ++ + YA K + S G+ L Sbjct: 122 LYASSSSVYGLNRKMPFSTDDSVDHPVSL----YAATKKANELMAHTYSHLYGLPATGLR 177 Query: 163 PCNLYGEFDKFEEKIAHMIPGLIARMHTAKLKNEKEFVMWGDGTARREYLNAKDLARFIS 222 +YG + + P + T + K ++ G +R++ D+A I Sbjct: 178 FFTVYGPWGR---------PDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAII 228 Query: 223 LAYENIASIPS-----------------VMNVGSGVDYSIEEYYKMIAQVLDYKGAFVKD 265 + I + V N+G+ + +Y + + L + Sbjct: 229 RLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNML 288 Query: 266 LSKPVGMQQKLMDISK-QKALKWELEIPLEQGIKEAYEYYLKLLEV 310 +P + + D + + + E ++ G+K +Y +V Sbjct: 289 PLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDFYKV 334
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 87.5 bits (217), Expect = 2e-21 Identities = 46/180 (25%), Positives = 72/180 (40%), Gaps = 19/180 (10%) Query: 7 LITGITGQDGSYLAEYLLNLGYEVHGLKRRSSSINTSRIDHLYEDLHSEHKRRFFLHYGD 66 L+TG G G ++++ LL G++V G+ + + S E L F H D Sbjct: 4 LVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQP---GFQFHKID 60 Query: 67 MTDSSNLIHLIATTKPTEIYNLAAQSHVKVSFETPEYTANADGIGTLRILEAMRILGLEK 126 + D + L A+ ++ + V+ S E P A+++ G L ILE R ++ Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ- 119 Query: 127 KTRFYQASTSELYGEVLETPQNENTPF-------NPRSPYAVAKMYAFYITKNYREAYNL 179 AS+S +YG N PF +P S YA K + Y Y L Sbjct: 120 --HLLYASSSSVYGL------NRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGL 171
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 32.1 bits (72), Expect = 0.003 Identities = 26/72 (36%), Positives = 37/72 (51%), Gaps = 8/72 (11%) Query: 190 KEETKEEETITIGDNTNAMKIVKKDIQKGYRALKSSQ--RKWYCLGICSKKSKLSLMPEE 247 KE+ +EE+ I D A+ + Q + ALK + R + K+SK +MP E Sbjct: 365 KEKIREEKQKIILDQAKAL-----ETQYVHNALKRNPVPRNYNYYQAPEKRSK-HIMPSE 418 Query: 248 IFNDKQFTYFKF 259 IF+D FTYF F Sbjct: 419 IFDDGTFTYFGF 430
>PF04335#VirB8 type IV secretion protein Length = 227 Score = 134 bits (338), Expect = 8e-41 Identities = 39/202 (19%), Positives = 74/202 (36%), Gaps = 4/202 (1%) Query: 40 QSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISVLPLQKTEHHF--VDFLNQDKHYAII 97 + K+A+ + G+ +A + + ++ PL+ E + VD + A Sbjct: 22 RDKLAAAERSKKLAWVVAGVAGALATAGVVAVAALTPLKTVEPYVITVDRNTGEASIAAK 81 Query: 98 QRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQN 157 D +I+ +EA+ + + YV RE + ++ V + S+ R+ KT N Sbjct: 82 LHGDATITYDEAVRKYFLATYVRYREGWIAAAREEYFDAVMVMSARPEQDRWSRFYKTDN 141 Query: 158 SIYVQSHLEREVHI-VNIAIYQQDNNPIASVSIAAKLMNENNLVYEKRYKIVLSYLFDTP 216 Q+ L + V I +A V + + +N + + Y D Sbjct: 142 PQSPQNILANRTDVFVEIKRVSFLGGNVAQVYFTKESVTGSNST-KTDAVATIKYKVDGT 200 Query: 217 DFDYASMPKNPTGFKVTRYSIT 238 KNP G++V Y Sbjct: 201 PSKEVDRFKNPLGYQVESYRAD 222
>LIPOLPP20#LPP20 lipoprotein precursor signature. Length = 175 Score = 293 bits (752), Expect = e-105 Identities = 174/175 (99%), Positives = 175/175 (100%) Query: 1 MKNQVKKILGMSVIAAMVIVGCSHAPKSGISKSNKAYKEATKGAPDWVVGDLEKVAKYEK 60 MKNQVKKILGMSV+AAMVIVGCSHAPKSGISKSNKAYKEATKGAPDWVVGDLEKVAKYEK Sbjct: 1 MKNQVKKILGMSVVAAMVIVGCSHAPKSGISKSNKAYKEATKGAPDWVVGDLEKVAKYEK 60 Query: 61 YSGVFLGRAEDLITNNDVDYSTNQATAKARANLAANLKSTLQKDLENEKTRTVDASGKRS 120 YSGVFLGRAEDLITNNDVDYSTNQATAKARANLAANLKSTLQKDLENEKTRTVDASGKRS Sbjct: 61 YSGVFLGRAEDLITNNDVDYSTNQATAKARANLAANLKSTLQKDLENEKTRTVDASGKRS 120 Query: 121 ISGTDTEKISQLVDKELIASKMLARYVGKDRVFVLVGLDKQIVDKVREELGMVKK 175 ISGTDTEKISQLVDKELIASKMLARYVGKDRVFVLVGLDKQIVDKVREELGMVKK Sbjct: 121 ISGTDTEKISQLVDKELIASKMLARYVGKDRVFVLVGLDKQIVDKVREELGMVKK 175
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 76.6 bits (188), Expect = 8e-22 Identities = 19/77 (24%), Positives = 40/77 (51%), Gaps = 1/77 (1%) Query: 34 EQKGGEFSKLLKQSINELNNTQEQSDKALADMVTGQIK-DLHQAAIAIGKAETSMKLMLE 92 Q F+ L +++ +++TQ + G+ L+ + KA SM++ ++ Sbjct: 27 PQPTISFAGQLHAALDRISDTQTAARTQAEKFTLGEPGVALNDVMTDMQKASVSMQMGIQ 86 Query: 93 VRNKAISAYKELLRTQI 109 VRNK ++AY+E++ Q+ Sbjct: 87 VRNKLVAAYQEVMSMQV 103
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 28.8 bits (64), Expect = 0.011 Identities = 10/38 (26%), Positives = 15/38 (39%) Query: 121 NVNAVVEMADLVEATRAYQANVAAFQSAKNMAQNAIGM 158 VN E +L + Y AN Q+A + I + Sbjct: 508 GVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 32.2 bits (73), Expect = 0.002 Identities = 30/183 (16%), Positives = 73/183 (39%), Gaps = 10/183 (5%) Query: 106 NVELLKKLSPDLVVTFVGNPKAVEHAKKF--GISFLSFQEKTIAEVMEDID---AQAKAL 160 N+ELL ++ P +V G + E + G F K + A L Sbjct: 88 NLELLTEMKPSFMVWSAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNL 147 Query: 161 EIDASKKFAKMQETLDFIKERL-KDVKKKKGVELFHKAN--KISGHQALDSDILEKGGID 217 + A A+ ++ + +K R K + + + G +L +IL++ GI Sbjct: 148 QSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYGIP 207 Query: 218 N-FGLKYVKFGRADVSVEKIVK-ENPEIIFIWWISPLTPEDVLNNPKFSTIKAIKNKQVY 275 N + + +G VS++++ ++ +++ + + ++ P + + ++ + Sbjct: 208 NAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNSKDMDALMATPLWQAMPFVRAGRFQ 267 Query: 276 KLP 278 ++P Sbjct: 268 RVP 270
>TYPE3IMPPROT#Type III secretion system inner membrane P protein family signature. Length = 224 Score = 29.4 bits (66), Expect = 0.029 Identities = 9/23 (39%), Positives = 12/23 (52%) Query: 4 LRYKLLLFVFIGFWGLLVLNLFI 26 KL+LFV + W LL L + Sbjct: 195 TPIKLVLFVALDGWTLLSKGLIL 217