>PF08280#M protein trans-acting positive regulator Length = 530 Score = 46.0 bits (109), Expect = 2e-07 Identities = 65/325 (20%), Positives = 128/325 (39%), Gaps = 29/325 (8%) Query: 19 KILNAFERRNELTTAELSDITEATTRTVVSDISSIKSYFGDSMLIESRNSGYRF-IELLP 77 +++ F + + L E+++ T T + + ++F DS+ + + Sbjct: 48 QLVVLFFKTSSLPITEVAEKTGLTFLQLNHYCEELNAFFPDSLSMTIQKRMISCQFTHPS 107 Query: 78 EEYTIKKRGILDDEPLFTIITAIFL--GEKRRSL-DWADKLYRSNKSMIIILKKLQEIVK 134 +E + + L + A + G R L D+A + SN S + + L +++ Sbjct: 108 KETYLYQ---LYASSNVLQLLAFLIKNGSHSRPLTDFARSHFLSNSSAYRMREALIPLLR 164 Query: 135 EYGFKLTYNPVDFVGSEQNIRKF--FLDFFYEGDVTPHTLTPSISIQNIVREFSVIYEQD 192 + KL+ N + VG E IR L + V T I + + S + Sbjct: 165 NFELKLSKNKI--VGEEYRIRYLIALLYSKFGIKVYDLTQQDKNIIHSFLSHSSTHLKTS 222 Query: 193 KQIVIQFSKFCYLLLIMFKRRQYKDDVTFSKEIR--KKVMEDIDFKHVEKLNEIILKTEK 250 + FS + LL + +KR Q+ + ++ + KK+ K + +II + Sbjct: 223 PWLSESFSFYDILLALSWKRHQFSVTIPQTRIFQQLKKLFVYDSLKKSSR--DIIETYCQ 280 Query: 251 FTLSENELIYLMLLWITNRN-IEDVKANEQYIQN----YMNNP---MLLEFSNDYCKMAE 302 S +L YL L++IT N ++ ++I+ + N +LL Sbjct: 281 LNFSAGDLDYLYLIYITANNSFASLQWTPEHIRQCCQLFEENDTFRLLLNPIITLLP--- 337 Query: 303 IELEDNQALFIRA--FFLSYYLKNL 325 L++ +A ++A FF +L NL Sbjct: 338 -NLKEQKASLVKALMFFSKSFLFNL 361
>PF05043#Transcriptional activator Length = 493 Score = 129 bits (326), Expect = 9e-35 Identities = 116/459 (25%), Positives = 199/459 (43%), Gaps = 10/459 (2%) Query: 1 MRELLSASDLRQLEIIEFLYATHSS-TLNKLSLAIRTSEKTLRQDIEKLNIMIAPSKIKV 59 MR+LLS RQLE++E L+ ++L+ + +E+ ++ D+ + P I Sbjct: 1 MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKDDLSHVKSAF-PDLIFH 59 Query: 60 SPKLGLMLQFSPQMSIESIYSLFLFSSTEFLIIESIFFHKSRTLDSLSESLFISKSTLRR 119 S G+ + + IE +Y F ST F I+E IFF++ +S+ + +IS S+L R Sbjct: 60 SSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQAESICKEFYISSSSLYR 119 Query: 120 TITTLNKNL-LPLNFQIDSQKLDLVGNESQICNFMIHYFQEKYKNSAAISPQIQLKVLDK 178 I+ +NK + F++ + ++GNE I F YF EKY + L + Sbjct: 120 IISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSEKYYFLEWPFENFSSEPLSQ 179 Query: 179 LFLLAMTNQKAEPNYPDLEKLRIGTIVILTRIKTDHKMVYSKKE----LSKIPPHMLNNV 234 L L N L++ + L RIK H M K Sbjct: 180 LLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFMEVDKDSFNDQSLDFLMQAEGIE 239 Query: 235 LVQRLFEATFSIPLTAETVYQLFYFFFNNNYCYDLDDLTRLSKKDSETAEFVTALYLFLE 294 V + FE+ ++I L E V QLF +F + D + KKDS + L F++ Sbjct: 240 GVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESLFMKCVKKDSYVEKSYHLLSDFID 299 Query: 295 NISKKLAINLTNQDELVLNLYNLDSLYYGK---TYILYDKYQAFIESVTHDYSDFYQFIQ 351 IS K I + N+D L+ +L+N LY + +IL+D+ I + + + F ++ Sbjct: 300 QISVKYQIEIENKDNLIWHLHNTAHLYRQELFTEFILFDQKGNTIRNFQNIFPKFVSDVK 359 Query: 352 NEINLDPYIKKKNWSQDAINSFFYMLITHWPDLANEIEKSIKVFSVGVFFSSDIEHTKML 411 E++ + S +N Y ITH L + ++ V V + D H K + Sbjct: 360 KELSHYLETLEVCSSSMMVNHLSYTFITHTKHLVINLLQNQPKLKVLVMSNFDQYHAKFV 419 Query: 412 YDQLSHLFQDKLNFTIINALTINELKKQAQNYDILITDL 450 + LS+ + + L +++ + YDI+I++ Sbjct: 420 AETLSYYCSNNFELEVWTELELSKESLEDSPYDIIISNF 458
>PF05043#Transcriptional activator Length = 493 Score = 57.6 bits (139), Expect = 5e-12 Identities = 50/239 (20%), Positives = 92/239 (38%), Gaps = 32/239 (13%) Query: 1 MLSFIDRDYSRQIQVLYFIKNSFRPVTIDEIADHIGSSTKTVLAILPVIKNDISMLN--- 57 M + + RQ+++L + R E+A+ + + + +K+D+S + Sbjct: 1 MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTER-------AVKDDLSHVKSAF 53 Query: 58 --FNLKKTKDRKYYLKSEIKDSQIYLDEYILFCGKRSLVFSIIEELFHKEKINTIEFCNK 115 + + + ++ D ++ + F K S FSI+E +F E C + Sbjct: 54 PDLIFHSSTNGIRIINTDDSDIEMVY--HHFF--KHSTHFSILEFIFFNEGCQAESICKE 109 Query: 116 RYISQATFSRGKKKIIELL-ATCDLKLPTYLTGGIIGNENKIRIFYLNFFSSFYSSVEWP 174 YIS ++ R +I +++ ++ IIGNE IR F+ +FS Y +EWP Sbjct: 110 FYISSSSLYRIISQINKVIKRQFQFEVSLT-PVQIIGNERDIRYFFAQYFSEKYYFLEWP 168 Query: 175 FEENITNNFERFFELKLGE--------------LFISINSKEKKNLLSRLYNKKKSNQR 219 FE + + EL E L + N K +K N + Sbjct: 169 FENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFMEVDKDSFNDQ 227
>PF05043#Transcriptional activator Length = 493 Score = 31.5 bits (71), Expect = 0.001 Identities = 14/61 (22%), Positives = 27/61 (44%), Gaps = 5/61 (8%) Query: 49 EQLFALGYSACFNSALEL--VMGQEKVSGKSQVTATVELLSDPSDNGFKLAVELDVAIEG 106 E++ + + F + + + V S V + LLSD D +++V+ + IE Sbjct: 255 EEVVCQLFVSYFQKMFFIDESLFMKCVKKDSYVEKSYHLLSDFID---QISVKYQIEIEN 311 Query: 107 K 107 K Sbjct: 312 K 312
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 35.3 bits (81), Expect = 4e-05 Identities = 24/136 (17%), Positives = 47/136 (34%), Gaps = 3/136 (2%) Query: 24 LKELIAQHPDNAELLYQCAWSHDTAGLEIEAVPYYEKAIQLGLEESDLSEAYVGLGSIYR 83 + L D E LY A++ +G +A ++ L +S ++GLG+ + Sbjct: 25 IAMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRF---FLGLGACRQ 81 Query: 84 TIGAYQKSKQLYLEALKKFPENKVYPIFLAMTYYNLAEYSQAMELLLRTISEIETDSEIK 143 +G Y + Y + +P A E ++A L I +E K Sbjct: 82 AMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQELIADKTEFK 141 Query: 144 TYQKAIAFYADKLDQI 159 ++ + + Sbjct: 142 ELSTRVSSMLEAIKLK 157
>PF07212#Hyaluronoglucosaminidase Length = 336 Score = 25.8 bits (56), Expect = 0.034 Identities = 14/34 (41%), Positives = 21/34 (61%) Query: 16 QTTKVESGISDKDIRFLKAKGLIINDRKLEYTDG 49 + TK+ES +DK+ +LKA+ I D+KL G Sbjct: 72 KITKLESSKADKNAVYLKAESKIELDKKLNLKGG 105
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.8 bits (69), Expect = 0.009 Identities = 16/83 (19%), Positives = 33/83 (39%), Gaps = 3/83 (3%) Query: 209 AAQIITEIQAAEKRKKEREEQRKKEEEARIARELEQEQLRAKCEEEARLAAERAELEKAN 268 AQ +E + + + + +KEE+A++ E QE + + + +A Sbjct: 1085 VAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAE 1144 Query: 269 EQQE---TYLEDDVLTEENYTED 288 +E T + ++ N T D Sbjct: 1145 PARENDPTVNIKEPQSQTNTTAD 1167
>BINARYTOXINA#Clostridial binary toxin A signature. Length = 454 Score = 28.5 bits (63), Expect = 0.010 Identities = 25/114 (21%), Positives = 50/114 (43%), Gaps = 7/114 (6%) Query: 6 PDVDVEATKKNARRVLRQYSRLEREAGKNYSQRLTVEISDMPRGSASIKSTPIEDMVIKK 65 + ++ KK A RV + LE+EA + Y + + +IS+ + IE Sbjct: 54 KENAIQWEKKEAERVEKNLDTLEKEALELYKKD-SEQISNYSQTRQYFYDYQIES----- 107 Query: 66 VTAEKKVWEILEAIYLLPRLSKEILWYSYIDKDHWSVTKIARALDYSDKAIEKY 119 EK+ + AI ++ K I Y + + ++ K R + ++ ++EK+ Sbjct: 108 NPREKEYKNLRNAI-SKNKIDKPINVYYFESPEKFAFNKEIRTENQNEISLEKF 160
>INTIMIN#Intimin signature. Length = 939 Score = 30.4 bits (68), Expect = 5e-04 Identities = 16/50 (32%), Positives = 28/50 (56%) Query: 21 LPANATDKTVQYSSNDVAIATVTPVQGKVTGVKAGSTTITATTVNGKTTT 70 L A+ + + S + AIA+V G+VT + G+TTI+ + + +T T Sbjct: 784 LKASGGNGKYTWRSANPAIASVDASSGQVTLKEKGTTTISVISSDNQTAT 833
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 86.4 bits (214), Expect = 1e-20 Identities = 56/306 (18%), Positives = 101/306 (33%), Gaps = 59/306 (19%) Query: 283 TVLVSGAGGSIGSEICRQIMKFHPSRLILLGHGE------NSIY---LIHKELGQIFGSD 333 LV+GA G IG + + RL+ GH N Y L L + + Sbjct: 2 KYLVTGAAGFIGFHVSK--------RLLEAGHQVVGIDNLNDYYDVSLKQARLELL--AQ 51 Query: 334 TDIIPVIADIQDRERIFEIMKEYRPDRVYHAAAHKHVPMMECNPKEAVKNNIYGTKNMAE 393 D+ DRE + ++ +RV+ + V NP +N+ G N+ E Sbjct: 52 PGFQFHKIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILE 111 Query: 394 AAKSADVGSFVMIST---------------DKAVNPPNVMGATKRIAEMIVTGLNEPGKT 438 + + + S+ D +P ++ ATK+ E++ + Sbjct: 112 GCRHNKIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGL 171 Query: 439 KFAAVRFGNVLGSRGS---VVPLFKEQIENGGPITV-TDFRMTRYFMTI----------- 483 +RF V G G + F + + G I V +M R F I Sbjct: 172 PATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQ 231 Query: 484 -------PEASRLVIQAGALAKGGEIFILDMGEPVKIVDLAKKVIKLSGYTEKEIAIIET 536 + + A ++ + PV+++D + + G E Sbjct: 232 DVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALG---IEAKKNML 288 Query: 537 GIRPGE 542 ++PG+ Sbjct: 289 PLQPGD 294
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 265 bits (679), Expect = 1e-89 Identities = 96/333 (28%), Positives = 153/333 (45%), Gaps = 27/333 (8%) Query: 14 FLITGGAGFIGSNLCEALLRMGYKVRCLDDLSTGKLENIQP----FFENENFEFIEGSIV 69 +L+TG AGFIG ++ + LL G++V +D+L+ +++ F+F + + Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDLA 62 Query: 70 DFDICDS--ACKGVNYVSNQAAWGSVPRSIEMPLKYEKINIKGTLNMMEAARQNNVKKVV 127 D + A V +V S+E P Y N+ G LN++E R N ++ ++ Sbjct: 63 DREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHLL 122 Query: 128 YASSSSVYGDEPNLPKKE-GIEGNVLSPYALTKKVAEEYGRLYSNLYGLETIGLRYFNVF 186 YASSSSVYG +P + +S YA TKK E YS+LYGL GLR+F V+ Sbjct: 123 YASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFFTVY 182 Query: 187 GRRQDPYGYYAAVIPKFVKALLNDEAPIFNGDGSQSRDFTYIENVIEANLKAM------- 239 G P + KF KA+L ++ G RDFTYI+++ EA ++ Sbjct: 183 GPWGRP----DMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHAD 238 Query: 240 ---------ISSSDVQGEAFNIAYGGQVSLIELYEELKVLLNKDVSPIFGPERVGDVKHS 290 ++S +NI V L++ + L+ L + P + GDV + Sbjct: 239 TQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQPGDVLET 298 Query: 291 NADISKAKEKLSYLPEFDFYMGIREAVNWYKHN 323 +AD E + + PE G++ VNWY+ Sbjct: 299 SADTKALYEVIGFTPETTVKDGVKNFVNWYRDF 331
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 40.2 bits (94), Expect = 9e-06 Identities = 66/365 (18%), Positives = 132/365 (36%), Gaps = 24/365 (6%) Query: 8 TAIGLYINYFVHGMGVIILAQNMDALGKQW---GTDSAGVAIVISSLGIGRLIVLMASGA 64 I + + +G+ ++ + L + +A I+++ + + GA Sbjct: 6 PLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGA 65 Query: 65 LSDKFGRRPFVYLGMFTYALFFAGILFSPSIAIAYIFGILAGIANSFLDSGTYPALMESF 124 LSD+FGRRP + + + A+ +A + +P + + YI I+AGI + + + + Sbjct: 66 LSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATG-AVAGAYIADIT 124 Query: 125 PESPGTANI-IIKAFISAGQFALPLMVGLI--VSTNMWYGWTFILAIIIFVVNGIYLFNK 181 + + A G A P++ GL+ S + + L + F+ G +L + Sbjct: 125 DGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLT-GCFLLPE 183 Query: 182 PFPDKEASISDK---PEESTNLAQPVRKVK-FAVEGVCFILYGYIAQATFYLVSQWLTKY 237 + + + P S A+ + V L G + A + + + + Sbjct: 184 SHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHW 243 Query: 238 GNEIAGMGDAASRALISYYSIGSLVCVFFTSALVKKKYKPVQFLVIYTFISFVALLILWL 297 G+ AA L SL T + + + + ++ I+ IL Sbjct: 244 DATTIGISLAAFGIL------HSLAQAMITGPVAARLGE--RRALMLGMIADGTGYILLA 295 Query: 298 FPTPLVCIIAAFVIGFSAAGGVLQLGLTVMAEMFPAG--KGKVTGIFYTAGSIASFTIPL 355 F T V A+GG+ L M +G++ G S+ S PL Sbjct: 296 FATRGWMAFPIMV--LLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPL 353 Query: 356 ITGQL 360 + + Sbjct: 354 LFTAI 358
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 46.7 bits (111), Expect = 8e-08 Identities = 58/369 (15%), Positives = 130/369 (35%), Gaps = 31/369 (8%) Query: 8 STVMALYINYILQGMAAIIVAQNMVPLMGQL---NTNAAGISIVISGIGFGRILILYFAG 64 ++ + L + ++ + L+ L N A I+++ + G Sbjct: 5 RPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLG 64 Query: 65 RMSDRYGRKKIVWLGMFSYVIFFGGILISQNMWMATFFTLFAGFANALLDTGTYPALM-- 122 +SDR+GR+ ++ + + + + + + +W+ + AG A TG Sbjct: 65 ALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGA---TGAVAGAYIA 121 Query: 123 -----EAYPEANGFMSVLNKAFISLGQLILPIVVGFL--IANNLYFGYSFILCLVALFAN 175 + GFMS A G + P++ G + + + F + L + Sbjct: 122 DITDGDERARHFGFMS----ACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTG 177 Query: 176 IFFMQKRRFPKLSQTSLAVEKEQKATKFNQKPVFLAEGLALTLFGFTSVSTFNII--VLW 233 F + + + + +E + + +A + F + + LW Sbjct: 178 CFLLPE---SHKGERR-PLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALW 233 Query: 234 LPRYAEELAGMAKSSSLMLVSLYSVGSMISVFITAFLIKKWMQPITMIVSCSIASLIVLI 293 + + A + + L + + S+ IT + + + ++ IA I Sbjct: 234 VIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGE-RRALMLGMIADGTGYI 292 Query: 294 LVILFPTPLGCSIAAFGIGIFSSGGIWQLALAILLEFF--PENKGRMTSYYTLMTSFSVM 351 L + F T + + +SGGI AL +L E +G++ +TS + + Sbjct: 293 L-LAFATRGWMAFPIM--VLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSI 349 Query: 352 LIPLITGNL 360 + PL+ + Sbjct: 350 VGPLLFTAI 358 Score = 35.6 bits (82), Expect = 3e-04 Identities = 25/127 (19%), Positives = 48/127 (37%), Gaps = 13/127 (10%) Query: 37 QLNTNAAGISIVISGIG-FGRILILYFAGRMSDRYGRKKIVWLGMFSYVIFFGGILISQN 95 + + +A I I ++ G + G ++ R G ++ + LGM + + + + Sbjct: 240 RFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATR 299 Query: 96 MWMA-TFFTLFAGFANALLDTGTYPAL-----MEAYPEANGFMSVLNKAFISLGQLILPI 149 WMA L A + PAL + E G + A SL ++ P+ Sbjct: 300 GWMAFPIMVLLASGGIGM------PALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPL 353 Query: 150 VVGFLIA 156 + + A Sbjct: 354 LFTAIYA 360
>SECYTRNLCASE#Preprotein translocase SecY subunit signature. Length = 437 Score = 30.9 bits (70), Expect = 0.016 Identities = 15/60 (25%), Positives = 28/60 (46%), Gaps = 4/60 (6%) Query: 27 GVISFLFVQSLILN--FILQYFQLHSSFNDTIQYALDKSS--LYLFSTLLIFIFLLFLYA 82 GVI +F SL+ + Q+ +S + ++ L K +Y+ + L+ +F F Y Sbjct: 275 GVIPVIFASSLLYIPALVAQFAGGNSGWKSWVEQNLTKGDHPIYIVTYFLLIVFFAFFYV 334
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 53.9 bits (129), Expect = 1e-09 Identities = 54/242 (22%), Positives = 99/242 (40%), Gaps = 26/242 (10%) Query: 51 QNPMLDSNHLESQVTSSSDPNNSTVVDETVTDRADSNSEASVEQE-QTPIQ--EEDANDT 107 ++ L ++ + Q+ + E + + E P++ E Sbjct: 65 EHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEESTPAAPMKFPLETVVRY 124 Query: 108 IQQQMNTRIFDELDTNPSKT---EAENFILSIVDPIKELSSTNDLYTSIMIAQAILESNY 164 Q ++ + + N + +++ F+ + P + S + + +++AQA LES + Sbjct: 125 QNQALSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQAALESGW 184 Query: 165 GKSDLAQP---GINNLFGMK----WKNIGEFYEKITTEQDQNGNEVLVSAKFKKFDSQYS 217 G+ + + NLFG+K WK G E TTE +NG V AKF+ + S Sbjct: 185 GQRQIRRENGEPSYNLFGVKASGNWK--GPVTEITTTEY-ENGEAKKVKAKFRVYSSYLE 241 Query: 218 GMVYYVDRLKKGPGFESGSTWNPYTGAWKSTTSNYLEAVNCISTSYATDGKYAEKLNNLI 277 + YV L + P + + +T ++ +A+ YATD YA KL N+I Sbjct: 242 ALSDYVGLLTRNPRYAAVTT--------AASAEQGAQALQ--DAGYATDPHYARKLTNMI 291 Query: 278 NQ 279 Q Sbjct: 292 QQ 293
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 176 bits (449), Expect = 4e-55 Identities = 74/341 (21%), Positives = 140/341 (41%), Gaps = 38/341 (11%) Query: 1 MNVLVTGGAGFIGSNYVHYMLENHPDYKIINLDLLTYAGNIHNLDDV---------IDNP 51 M LVTG AGFIG + +LE ++++ +D N+++ DV + P Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEA--GHQVVGID------NLNDYYDVSLKQARLELLAQP 52 Query: 52 NHVFVEGNICNRELVRNLVKTHSITHFVNFAAESHVDRSILNPEIFVETNIQGTLALLDV 111 F + ++ +RE + +L + V S+ NP + ++N+ G L +L+ Sbjct: 53 GFQFHKIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEG 112 Query: 112 AKELSIEKYLQVSTDEVYGSLGAEGYFTEETPLA-PNSPYSASKTGADLLVRAYFETYGM 170 + I+ L S+ VYG L + F+ + + P S Y+A+K +L+ Y YG+ Sbjct: 113 CRHNKIQHLLYASSSSVYG-LNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGL 171 Query: 171 NVNITRCSNNYGPYHFPEKLIPLMISNGMDNKELPIYGDGLNIRDWLHVQDHCQAIDLVL 230 R YGP+ P+ + ++ K + +Y G RD+ ++ D +AI + Sbjct: 172 PATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQ 231 Query: 231 HKGRK------------------GEVYNVGGHNERTNNEIVEIVIEKLGLSRDLIKYVDD 272 VYN+G + + ++ + + LG+ + Sbjct: 232 DVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAK-KNMLPL 290 Query: 273 RLGHDKRYAIDPTKLETELGWKPKYTFDTGIVETIEWYQAN 313 + G + D L +G+ P+ T G+ + WY+ Sbjct: 291 QPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDF 331
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 58.3 bits (141), Expect = 6e-12 Identities = 38/197 (19%), Positives = 68/197 (34%), Gaps = 35/197 (17%) Query: 1 MTVLITGSNGQLGTELKKLLAEQNIEYIAADA------------------------NSMD 36 M L+TG+ G +G + K L E + + D + +D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 37 ITDEAKVNSFVKEVRPSIIYHCAAYTAVDKAEDEGKELNQLINVDGTRYVAKAAEEND-A 95 + D + ++ AV + + N+ G + + N Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADS-NLTGFLNILEGCRHNKIQ 119 Query: 96 VIVYISTDYVFDGNKNDEYKVEDIPN-PQNEYGRAKYEGELEVQKYASKYYI----IRTS 150 ++Y S+ V+ N+ + +D + P + Y K EL Y+ Y + +R Sbjct: 120 HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFF 179 Query: 151 WVYGEFG----ANFVFT 163 VYG +G A F FT Sbjct: 180 TVYGPWGRPDMALFKFT 196
>SECA#SecA protein signature. Length = 901 Score = 1117 bits (2890), Expect = 0.0 Identities = 425/904 (47%), Positives = 584/904 (64%), Gaps = 73/904 (8%) Query: 1 MANFLKQLIEN-DKKEIKSLEKVADKIDAYGDRMAALSDEELQAKTPEFKKRYQAGETLD 59 + L ++ + + + ++ + KV + I+A M LSDEEL+ KT EF+ R + GE L+ Sbjct: 2 LIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVLE 61 Query: 60 DLLPEAFAVVREAAKRVLGLYPYRVQLMGGMTLHKGNIPEMKTGEGKTLTATMPVYLNAL 119 +L+PEAFAVVREA+KRV G+ + VQL+GGM L++ I EM+TGEGKTLTAT+P YLNAL Sbjct: 62 NLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNAL 121 Query: 120 AGEGVHVVTVNEYLASRDATEMGELYTFLGLTVGLNLNSKSSEEKREAYNADITYSTNNE 179 G+GVHVVTVN+YLA RDA L+ FLGLTVG+NL + KREAY ADITY TNNE Sbjct: 122 TGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNNE 181 Query: 180 LGFDYLRDNMVVYREQMVQRPLNYAIVDEVDSILIDEARTPLIISGQAEKSTALYTRADF 239 GFDYLRDNM E+ VQR L+YA+VDEVDSILIDEARTPLIISG AE S+ +Y R + Sbjct: 182 YGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVNK 241 Query: 240 FVKSLT-----------AEADYTIDVQSKTIALTEEGMVKAEKTF-------KVENLYDI 281 + L E +++D +S+ + LTE G+V E+ + E+LY Sbjct: 242 IIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYSP 301 Query: 282 DNTALIHHIDQALRANYIMLRDIDYVVQEGEVLIVDQFTGRIMDGRRYSDGLHQAIEAKE 341 N L+HH+ ALRA+ + RD+DY+V++GEV+IVD+ TGR M GRR+SDGLHQA+EAKE Sbjct: 302 ANIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKE 361 Query: 342 GVEIENESKTMANVTFQNFFRMYKKLSGMTGTAKTEQEEFREIYNIQVVEIPTNKPIIRD 401 GV+I+NE++T+A++TFQN+FR+Y+KL+GMTGTA TE EF IY + V +PTN+P+IR Sbjct: 362 GVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIRK 421 Query: 402 DRPDLLYPTLTSKFNAVVEDIKTRHAKGQPILVGTVAVETSELLSDLLTKAKIHHEVLNA 461 D PDL+Y T K A++EDIK R AKGQP+LVGT+++E SEL+S+ LTKA I H VLNA Sbjct: 422 DLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNA 481 Query: 462 KNHFKEAEIIMSAGQKGAVTIATNMAGRGTDIKLGA------------------------ 497 K H EA I+ AG AVTIATNMAGRGTDI LG Sbjct: 482 KFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKADW 541 Query: 498 -----GVIEAGGLCVIGTERHESRRIDNQLRGRAGRQGDPGVTQFYLSLEDELMKRFGSE 552 V+EAGGL +IGTERHESRRIDNQLRGR+GRQGD G ++FYLS+ED LM+ F S+ Sbjct: 542 QVRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASD 601 Query: 553 RIQAILERLRVQEEDAVIQSKMISRQVESAQKRVEGNNYDTRKNVLEYDDVMREQREIMY 612 R+ ++ +L ++ +A I+ +++ + +AQ++VE N+D RK +LEYDDV +QR +Y Sbjct: 602 RVSGMMRKLGMKPGEA-IEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIY 660 Query: 613 GQRLEVIMATESLKKITMAMIQRTVNRMVS--VNTQGNKEEWNLQGIHDFATSAIVHEDS 670 QR E ++ + + ++ + + + Q +E W++ G+ + + + Sbjct: 661 SQRNE-LLDVSDVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLD-- 717 Query: 671 LTVQDLENKTPEEIEALLMKRV----EDIYTTKEQQF-NEQMLEFEKVVILRVVDSKWTD 725 L + + +K PE E L +R+ ++Y KE+ E M FEK V+L+ +DS W + Sbjct: 718 LPIAEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKE 777 Query: 726 HIDTMDQLRQGIGLRAYAQTNPLVEYQAEGFKLFEEMIAAIEYDVTRLLMKSEIR----- 780 H+ MD LRQGI LR YAQ +P EY+ E F +F M+ +++Y+V L K ++R Sbjct: 778 HLAAMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEV 837 Query: 781 ------QNLQREQVAQGSPARSTGDGDVVEAAKHKPVKNDD-KIGRNDPCPCGSGKKYKN 833 + ++ E++AQ D AA + + K+GRNDPCPCGSGKKYK Sbjct: 838 EELEQQRRMEAERLAQMQQLSHQDDDS--AAAAALAAQTGERKVGRNDPCPCGSGKKYKQ 895 Query: 834 CHGK 837 CHG+ Sbjct: 896 CHGR 899
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 39.7 bits (92), Expect = 2e-05 Identities = 38/193 (19%), Positives = 63/193 (32%), Gaps = 10/193 (5%) Query: 77 ATQETLKTLTTEVTALNEKIAQREDKLKEQARTIQVNGDTQNYIDFVLSAKSFGDVVGRV 136 A + L+ + N ++ +R + I + Q V S S + + RV Sbjct: 966 AWKYKLRNVNGRYDLYNPEVEKRNQTVD--TTNITTPNNIQAD---VPSVPSNNEEIARV 1020 Query: 137 DVVSQMVSANQDLVKEQKSDKEEVASKQKETETKSQEQALLAAKLEATKADLEQQKLEKE 196 D V + ++ SKQ+ + EQ + + ++ K + Sbjct: 1021 D--EAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVA-KEAKSNVK 1077 Query: 197 AIVATLASEQSGAESEKASFLAKKE--DAEKAAKAIATANAAPVVAVQTSTTAPAATPVA 254 A T QSG+E+++ KE EK KA V TS +P Sbjct: 1078 ANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSE 1137 Query: 255 ENNAPATPAAPPV 267 A PA Sbjct: 1138 TVQPQAEPAREND 1150 Score = 33.9 bits (77), Expect = 0.001 Identities = 35/182 (19%), Positives = 60/182 (32%), Gaps = 17/182 (9%) Query: 86 TTEVTALNEKIAQREDKLKEQ------ARTIQVNGDTQNYIDFVLSAKSFGDVVGRVDVV 139 TTE A N K + + EQ A+ +V + ++ + Sbjct: 1036 TTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKET 1095 Query: 140 SQMVSANQDLVKEQKSDKEEVASKQKETETKSQEQALLAAKLEATKADLEQQKLEKEAIV 199 + V++++ K E Q+ + SQ + K E ++ Q + +E Sbjct: 1096 QTTETKETATVEKEEKAKVETEKTQEVPKVTSQV----SPKQEQSETVQPQAEPARENDP 1151 Query: 200 ATLASEQSGAESEKASFLAKKEDAEKAAKAIATANAAPVVAVQTSTTAPAATPVAENNAP 259 E + A D E+ AK ++ PV T T + EN P Sbjct: 1152 TVNIKEPQSQTNTTA-------DTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTP 1204 Query: 260 AT 261 AT Sbjct: 1205 AT 1206
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 93.0 bits (231), Expect = 6e-24 Identities = 34/151 (22%), Positives = 78/151 (51%), Gaps = 4/151 (2%) Query: 3 KVLIVDDEESILTLLAFNLEKAGYEVQTAMDGLIGYQLALENQYDFIILDLMMPSMDGME 62 +L+ DD+ +I T+L L +AGY+V+ + ++ D ++ D++MP + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 63 VCKKLRQEKIETPIMILTAKDDELEKIIGLELGADDYMTKPFSPREVLARMKAIMRRIKP 122 + ++++ + + P+++++A++ + I E GA DY+ KPF E++ + R Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGI----IGRALA 120 Query: 123 ESKEKMAESHETSPEEEVVIGELQIFPELYE 153 E K + ++ + S + ++G E+Y Sbjct: 121 EPKRRPSKLEDDSQDGMPLVGRSAAMQEIYR 151
>PF06580#Sensor histidine kinase Length = 349 Score = 32.9 bits (75), Expect = 0.003 Identities = 27/170 (15%), Positives = 62/170 (36%), Gaps = 38/170 (22%) Query: 427 LSKLEQKQVPLEQELIEVQ-----EAVRSSFRL-VKHKADEKNMNLLLNDADPIYLLGDS 480 L +QV L EL V +++ RL +++ + M++ + P L+ Sbjct: 208 LRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQV----PPMLV--- 260 Query: 481 GRLKQIITNLLTNAVSYTEADGKVEVFVEQSETEATIKISDNGMGIPEAELDRIFERFYR 540 + ++ N + + ++ GK+ + + T+++ + G + Sbjct: 261 ---QTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALK------------ 305 Query: 541 VDKARSRNSGGTGLGLSIVKYLVENFNG---TIQVESKLGLGTTFTIILP 587 TG GL V+ ++ G I++ K G +++P Sbjct: 306 ------NTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQG-KVNAMVLIP 348