>PF02370#M protein repeat Length = 168 Score = 43.6 bits (102), Expect = 4e-07 Identities = 24/153 (15%), Positives = 56/153 (36%), Gaps = 18/153 (11%) Query: 428 ATRGAQAAVHDALAANNQDLEMQQERMQDAQDALQEAREQLASLGPELA-----QAKQDA 482 ++ G ++ L N L+ Q E D+ D+ +E Q +L E + + Sbjct: 10 SSNGKLITEYNKLVEENSKLQKQLEEYLDSSDSKRENDPQYRALMGENQDLRKREGQYQD 69 Query: 483 QQQAREAEQQIREVAQQHRQAQYAYAAAVRQAAALSRQQAEMGKQAARQARIEAARGQQQ 542 + + E E++ ++ + R+ + Q E + A + ++ + Q Sbjct: 70 KIEELEKERKEKQERPERREKFERQHQDKHYQEQQKKHQQEQQQLEAEKQKLAKEK---Q 126 Query: 543 AAQAQRE----------AAQAQADAEQAQAEAE 565 + A R+ AA+ + + + + E Sbjct: 127 ISDASRQGLNRDLEASRAAKKELEPKHQKLGTE 159 Score = 40.9 bits (95), Expect = 3e-06 Identities = 29/120 (24%), Positives = 57/120 (47%), Gaps = 5/120 (4%) Query: 438 DALAANNQDLEMQQERMQDAQDALQEAREQLASLGPELAQAKQDAQQQAREAEQQIREVA 497 AL NQDL ++ + QD + L++ R++ + K + Q Q + ++Q ++ Sbjct: 51 RALMGENQDLRKREGQYQDKIEELEKERKEKQE--RPERREKFERQHQDKHYQEQQKKHQ 108 Query: 498 QQHRQ--AQYAYAAAVRQAAALSRQQAEMGKQAARQARIE-AARGQQQAAQAQREAAQAQ 554 Q+ +Q A+ A +Q + SRQ +A+R A+ E + Q+ + Q+ + Q Sbjct: 109 QEQQQLEAEKQKLAKEKQISDASRQGLNRDLEASRAAKKELEPKHQKLGTEHQKLKEEKQ 168
>THERMOLYSIN#Thermolysin metalloprotease (M4) family signature. Length = 544 Score = 283 bits (724), Expect = 2e-93 Identities = 118/288 (40%), Positives = 165/288 (57%), Gaps = 23/288 (7%) Query: 74 YDARQGTALPGVLVRE--EGAPPTDDVAVTEAYDYLGATHAFFQQVYARNSIDDAGMPLL 131 YD R T LPG L + + D A +A+ Y G + +++ V+ R S D + + Sbjct: 270 YDGRNRTVLPGSLWADGDNQFFASYDAAAVDAHYYAGVVYDYYKNVHGRLSYDGSNAAIR 329 Query: 132 GTVHYERNYDNAFWTGEQMVFGDGDGEIFTRFTIAIDVVAHELTHGVIERTANLIYQGQS 191 TVHY R Y+NAFW G QMV+GDGDG+ F F+ IDVV HELTH V + TA L+YQ +S Sbjct: 330 STVHYGRGYNNAFWNGSQMVYGDGDGQTFLPFSGGIDVVGHELTHAVTDYTAGLVYQNES 389 Query: 192 GALNESVSDVFGVLVKQYALRQDAAQADWLVGAGMFLPGVQGVALRSMQAPGTAYDDPAL 251 GA+NE++SD+FG LV+ YA R DW +G ++ PGV G ALRSM P Sbjct: 390 GAINEAMSDIFGTLVEFYANRNP----DWEIGEDIYTPGVAGDALRSMSDP--------- 436 Query: 252 GKDPQPAHMDAYVDTQEDDGGVHYNSGIPNRAFQRAA-------VAIGGYAWEKAGRIWY 304 K P H +D+GGVH NSGI N+A + V++ G +K G+I+Y Sbjct: 437 AKYGDPDHYSKRYTGTQDNGGVHTNSGIINKAAYLLSQGGVHYGVSVTGIGRDKMGKIFY 496 Query: 305 RALTGGALSASADFATFAALTVRVASTDYGAGSAEASAVEQAWRDVGV 352 RAL L+ +++F+ A V+ A+ YG+ S E ++V+QA+ VGV Sbjct: 497 RALV-YYLTPTSNFSQLRAACVQAAADLYGSTSQEVNSVKQAFNAVGV 543
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 41.3 bits (97), Expect = 7e-06 Identities = 55/307 (17%), Positives = 103/307 (33%), Gaps = 39/307 (12%) Query: 71 PTAQLIATFATFTVAF-LVRPIGGMVFGPLGDRYGRQKVLAATMILMALGTFSIGLIPSY 129 + + A + + L++ V G L DR+GR+ VL ++ A+ + P Sbjct: 37 HSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPF- 95 Query: 130 AQIGLWAPALLLLARLLQGFSTGGEYGGAATFIAEYATDRNR----GLMGSWLEFGTLGG 185 LW +L + R++ G TG A +IA+ R G M + FG + G Sbjct: 96 ----LW---VLYIGRIVAGI-TGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAG 147 Query: 186 YIAGAATVTALHMALSQAQMLDWGWRVPFLVAGPLGLLGLYMRMKLEETPAFRAYTEQSE 245 + G M + PF A L L L Sbjct: 148 PVLGGL-------------MGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRR 194 Query: 246 QRERETAGQGLMTLLRLHWPQLLKCVGLVLVFNVTDYMLLTYMPS---YLSVTMGYAESK 302 + A + + + + LV V + + + + + T+G + + Sbjct: 195 EALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAA 254 Query: 303 GLLLIILVMLVMMPLNVVGGMFSDKLGRRPMIIGACAALFALAIPCLLLIGSGSDVLIFT 362 +L L ++ G + +LG R ++ + A +LL + + F Sbjct: 255 FGILHSLAQAMIT------GPVAARLGERRALM---LGMIADGTGYILLAFATRGWMAFP 305 Query: 363 GLMLLGL 369 ++LL Sbjct: 306 IMVLLAS 312 Score = 29.8 bits (67), Expect = 0.027 Identities = 22/103 (21%), Positives = 44/103 (42%), Gaps = 9/103 (8%) Query: 267 LLKCVGLVLVFNVTDYMLLTYMPSYLSVTMGYAESKGLLLIILVMLVMMPLNVVGGMFSD 326 L VG+ L+ V +L + S + +L+ L L+ V G SD Sbjct: 15 ALDAVGIGLIMPVLPGLLRDLVHS------NDVTAHYGILLALYALMQFACAPVLGALSD 68 Query: 327 KLGRRPMIIGACAALFALAIPCLLLIGSGSDVLIFTGLMLLGL 369 + GRRP++ +L A+ ++ + +++ G ++ G+ Sbjct: 69 RFGRRPVL---LVSLAGAAVDYAIMATAPFLWVLYIGRIVAGI 108
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 36.8 bits (85), Expect = 9e-05 Identities = 20/102 (19%), Positives = 32/102 (31%), Gaps = 3/102 (2%) Query: 96 DPNQFNAYVMQAHLAVARGDLDEAERLSRTAARLAPEHPQLLAVDGVVEMRRGQSDRALS 155 Q + + + G ++A ++ + L + G GQ D A+ Sbjct: 35 TLEQLYSLAFNQYQS---GKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIH 91 Query: 156 LLTRAAEQLPDDARVMFALGFAYLQKEHFAFAERAFERVVEL 197 + A + R F LQK A AE EL Sbjct: 92 SYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQEL 133
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 495 bits (1277), Expect = e-175 Identities = 206/470 (43%), Positives = 279/470 (59%), Gaps = 14/470 (2%) Query: 10 RIWVVDDDRSVRFVLSTALRDAGYAVDGFDSAAAALQALAMRPTPDLLFTDVRMPGEDGL 69 I V DDD ++R VL+ AL AGY V +AA + +A DL+ TDV MP E+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIA-AGDGDLVVTDVVMPDENAF 63 Query: 70 TLLDKLKSKHPQLPVIVMSAYTDVASTAGAFRGGAHEFLSKPFDLDDAVALAARALPDAD 129 LL ++K P LPV+VMSA + A GA+++L KPFDL + + + RAL + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 130 AAVEDTLGTPVAEGSAALIGDTPAMQALFRAIGRLAQAPLSVLINGETGTGKELVARALH 189 ++ L+G + AMQ ++R + RL Q L+++I GE+GTGKELVARALH Sbjct: 124 RRPSKLEDD--SQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALH 181 Query: 190 NESPRSRKPFVALNTAAIPAELLESELFGHETGAFTGATKRHIGRFEQADGGTLFLDEIG 249 + R PFVA+N AAIP +L+ESELFGHE GAFTGA R GRFEQA+GGTLFLDEIG Sbjct: 182 DYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIG 241 Query: 250 DMPLPLQTRLLRVLAENEFFRVGGRELIRVDVRVIAATHQDLEALVEQGRFRADLLHRLD 309 DMP+ QTRLLRVL + E+ VGGR IR DVR++AAT++DL+ + QG FR DL +RL+ Sbjct: 242 DMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLN 301 Query: 310 VVRLQLPPLRERRGDIAQLAENFLAMAGRKLDMLPKRLSSAALEALRQYDWPGNVRELEN 369 VV L+LPPLR+R DI L +F+ A K + KR ALE ++ + WPGNVRELEN Sbjct: 302 VVPLRLPPLRDRAEDIPDLVRHFVQQA-EKEGLDVKRFDQEALELMKAHPWPGNVRELEN 360 Query: 370 VCWRLAALATADTIDVVDV---------DAALARGGRRVRAGRSDGQWDEMLSSWAAQRL 420 + RL AL D I + D+ + + R + +E + + A Sbjct: 361 LVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFG 420 Query: 421 SE-GAQGLHAEARERLDKTLLEAALQLTQGRRAEAAARLGLGRNTVTRKL 469 GL+ ++ L+ AAL T+G + +AA LGL RNT+ +K+ Sbjct: 421 DALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKI 470
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 143 bits (363), Expect = 2e-42 Identities = 80/362 (22%), Positives = 135/362 (37%), Gaps = 78/362 (21%) Query: 1 MKILVTGGGGFLGQALCRGLVARGHEVV-----------SFQRGDYPVLHTLGVGQIRGD 49 MK LVTG GF+G + + L+ GH+VV S ++ +L G + D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 50 LADPQAVRHALA--GIDAVFHNAAKAG---AWGSYDSYHQANVVGTQNVLDACRANGVPR 104 LAD + + A + VF + + + + +Y +N+ G N+L+ CR N + Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 105 LIYTSTPSVTHRATNPVEGLGADE-VPYGEDLRA-----PYAATKAIAERAVLAANDA-Q 157 L+Y S+ SV G + +P+ D YAATK E + Sbjct: 121 LLYASSSSV----------YGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYG 170 Query: 158 LATVALRPRLIWGP-GD-NHLLPRLAARARAGR-LRMVGDGSNLVDSTYIDNAAQAHFDA 214 L LR ++GP G + L + G+ + + G D TYID+ A+A Sbjct: 171 LPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRL 230 Query: 215 ------------FAHLAPGAACA-GKAYFISNGEPLPMRELLNRLLAAVDAPAVTRSLSF 261 P A+ A + Y I N P+ + + + L A+ A L Sbjct: 231 QDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPL 290 Query: 262 KTAYRIGAVCETLWPLLRLPGEVPLTRFLVEQLCTPHWYSMEPARRDFGYVPQISIEEGL 321 + PG+V T + G+ P+ ++++G+ Sbjct: 291 Q------------------PGDVLET-----------SADTKALYEVIGFTPETTVKDGV 321 Query: 322 QR 323 + Sbjct: 322 KN 323
>PF04335#VirB8 type IV secretion protein Length = 227 Score = 24.0 bits (52), Expect = 0.029 Identities = 5/20 (25%), Positives = 9/20 (45%) Query: 28 TNIAWILFVVFLILAVISMF 47 +AW++ V LA + Sbjct: 32 KKLAWVVAGVAGALATAGVV 51
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 28.1 bits (62), Expect = 0.004 Identities = 24/97 (24%), Positives = 37/97 (38%), Gaps = 7/97 (7%) Query: 1 AVEILSVYLARELEPRSITANTVARGAIATGFP-------GGAVRDTPAYTKAFADMTAL 53 A + + L EL +I N V+ G+ T GA + + F L Sbjct: 163 AAVMFTKCLGLELAEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPL 222 Query: 54 GRVGVPDDIGPMVASLLSEDNRWVTGQRIEVSGGQTI 90 ++ P DI V L+S +T + V GG T+ Sbjct: 223 KKLAKPSDIADAVLFLVSGQAGHITMHNLCVDGGATL 259
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 38.7 bits (90), Expect = 4e-05 Identities = 28/143 (19%), Positives = 53/143 (37%), Gaps = 1/143 (0%) Query: 46 LTPIAADLHATAGMAGQAISISGLFAVLASLLIAPLTSRFN-RRHVLISLSAVMLLSLLL 104 L IA D + + L + + + L+ + +R +L + S++ Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 105 IANAHSFGMLMAARALLGITIGGFWALATATVMRMMPEEAVPKALGIVYIGNAVATAFAA 164 F +L+ AR + G F AL V R +P+E KA G++ A+ Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 165 PLGSYLGAVIGWRGVFWGMVPLV 187 +G + I W + + + Sbjct: 157 AIGGMIAHYIHWSYLLLIPMITI 179
>SALSPVBPROT#Salmonella virulence plasmid 65kDa B protein signature. Length = 591 Score = 32.0 bits (72), Expect = 0.006 Identities = 12/30 (40%), Positives = 18/30 (60%), Gaps = 3/30 (10%) Query: 56 GDGFWLIHEPDGRVHAIDACGRAAQAATLD 85 GD FWL+H+ +G +H + G+ A A D Sbjct: 155 GDDFWLLHDSNGILHLL---GKTAAARLSD 181
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 99.0 bits (246), Expect = 5e-27 Identities = 65/240 (27%), Positives = 99/240 (41%), Gaps = 14/240 (5%) Query: 2 QTVLITGCSSGFGLATAHYFLERDWNVVATMRTPREDLFPVSPRL------KVLQLDVTD 55 + ITG + G G A A + ++ A P + VS + DV D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 56 AASI----QAAIAAAGTVDTLVNNAGFGAPAPLELTSLQAVRDLFETNTFGTLAVTQAVL 111 +A+I G +D LVN AG P + S + F N+ G +++V Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 112 PQMRARRAGVIVNVSSSATLKPLPLIGAYRAAKAAVNALSESLAAELEAFGIRVRVISPG 171 M RR+G IV V S+ P + AY ++KAA ++ L EL + IR ++SPG Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 172 SCGETDFRATARAGLRGADDEIYGAFMQQTLARMSASTGPGTRSIDVAQAVWRAATDPAA 231 S ETD + + A GA+ I G+ + + D+A AV + A Sbjct: 189 ST-ETDMQWSLWADENGAEQVIKGSLET---FKTGIPLKKLAKPSDIADAVLFLVSGQAG 244
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 38.6 bits (90), Expect = 2e-05 Identities = 27/130 (20%), Positives = 41/130 (31%), Gaps = 35/130 (26%) Query: 8 ILVTGASGHLGALIVDALLERVPAGRIVA---------TARETASLSAFAKRDISVRRAD 58 LVTGA+G +G + LLE ++V + + A L A+ + D Sbjct: 3 YLVTGAAGFIGFHVSKRLLEA--GHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 59 YADPASLD--------------AAFAGVGTVL-----LVSSNAVGARVEQHRNVIEAAKR 99 AD + V L SN G N++E + Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTG-----FLNILEGCRH 115 Query: 100 AGVGLLAYTS 109 + L Y S Sbjct: 116 NKIQHLLYAS 125
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 30.7 bits (69), Expect = 0.002 Identities = 12/58 (20%), Positives = 24/58 (41%), Gaps = 3/58 (5%) Query: 71 VVDIAVLPAHQGRGLGKTVMGEIASYIEREVPASAYVSLIADG--AAYKLYQQFGFAL 126 + DIAV ++ +G+G ++ A +E + D +A Y + F + Sbjct: 92 IEDIAVAKDYRKKGVGTALLH-KAIEWAKENHFCGLMLETQDINISACHFYAKHHFII 148
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 35.8 bits (82), Expect = 1e-04 Identities = 29/184 (15%), Positives = 53/184 (28%), Gaps = 24/184 (13%) Query: 37 GGVQLLGTAFALDKPGLFATASHVAGTEGQNLV-LAFKPLAALHDYQDTGDTSIRSFPVQ 95 + + + T HV + L P A D G + Q Sbjct: 98 PTGTFIASGVVVG-KDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAE----Q 152 Query: 96 IHALDPFHDLAVLKADVISTSS--------VVVGGADDATVGTQVASFGFPHADHCRMVL 147 I DLA++K + + + V + G+P V Sbjct: 153 ITKYSGEGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKP---VA 209 Query: 148 TQQDAEIGARVLIASGGIKAKHLVLNTQARPGQSGSPIFRKTDGRLVGVLVGSYAPGGGG 207 T +++ L + + G SGSP+F + ++G+ G G Sbjct: 210 TMWESKGKITYLKGEA------MQYDLSTTGGNSGSPVFNE-KNEVIGIHWGGVPNEFNG 262 Query: 208 GISL 211 + + Sbjct: 263 AVFI 266
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 33.0 bits (75), Expect = 0.002 Identities = 16/40 (40%), Positives = 19/40 (47%), Gaps = 1/40 (2%) Query: 172 IGQDEVAEAPFEVVHGDRTVTVSRWMHNIDPPPFWAGQIA 211 IG D V + V +G TV V+ I P PF GQ A Sbjct: 274 IGAD-VRISRVAVSYGTLTVQVTESPQVIQPAPFSRGQTA 312
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 37.0 bits (85), Expect = 2e-05 Identities = 12/55 (21%), Positives = 22/55 (40%), Gaps = 7/55 (12%) Query: 102 PNGRPNGPRPQRPNPPPATGAPPRPAQPPRIGAPPRVIREIQRQTAPRNTRQQIP 156 G+ + Q P+ P A P + AP + Q + + T++Q+P Sbjct: 459 RAGKASDS--QTPDAKPG-----NKAVPGKGQAPQAGTKPNQNKAPMKETKRQLP 506
>DPTHRIATOXIN#Diphtheria toxin signature. Length = 567 Score = 29.3 bits (65), Expect = 0.017 Identities = 18/69 (26%), Positives = 31/69 (44%), Gaps = 1/69 (1%) Query: 37 ESLDYLGDTAPKVVLDVGAGPGHASATIKKRWPKAQVIALDQALPM-LRQARKTAGWWKP 95 E + GD A +VVL + G +S W +A+ ++++ + R R ++ Sbjct: 154 EFIKRFGDGASRVVLSLPFAEGSSSVEYINNWEQAKALSVELEINFETRGKRGQDAMYEY 213 Query: 96 FAQVCADAR 104 AQ CA R Sbjct: 214 MAQACAGNR 222
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 90.1 bits (223), Expect = 1e-23 Identities = 73/258 (28%), Positives = 106/258 (41%), Gaps = 5/258 (1%) Query: 4 GIAGRWALVCAASKGLGLGCAQALAREGANVVIVARGREALEQSASNLRALPGAGEVRSV 63 GI G+ A + A++G+G A+ LA +GA++ V E LE+ S+L+A E Sbjct: 5 GIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPA 64 Query: 64 -VADITTSEGRAAALAA-CPQVDILINNAGGPPPGDFRQWERADWLRALDANMLAPIELI 121 V D + A + +DIL+N AG PG +W N Sbjct: 65 DVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNAS 124 Query: 122 RATVDAMRARRFGRIVNITSSAVKAPIDILGLSNGARAGLTGFVAGLARSTVADNVTLNN 181 R+ M RR G IV + S+ P + ++A F L N+ N Sbjct: 125 RSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184 Query: 182 LLPGQFATDRLRGNFAA-IAEQQGTSAEAVAAHKRAGIPAGRFGEPDEFGAACAFLCSAQ 240 + PG TD +A +Q + GIP + +P + A FL S Q Sbjct: 185 VSPGSTETDMQWSLWADENGAEQVIKGS--LETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 241 AGYITGQNLLIDGGAYPG 258 AG+IT NL +DGGA G Sbjct: 243 AGHITMHNLCVDGGATLG 260
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 26.3 bits (57), Expect = 0.009 Identities = 15/54 (27%), Positives = 26/54 (48%) Query: 3 ADDHGRQESNRQSVLGELDFRYFPQQQRRERRLIRPQYEERTFALADYFQSPLE 56 + ++G QE + +G RY P Q + +RR I Q+ + L Q+ L+ Sbjct: 45 STENGWQEFESYADVGVDPRRYVPLQVKEKRREIELQFRDAEKKLEASVQAELD 98
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 119 bits (300), Expect = 7e-35 Identities = 79/251 (31%), Positives = 113/251 (45%), Gaps = 9/251 (3%) Query: 11 VLIAGGSRGIGLAIAQAFVQSGAQVSLCARNPEGLANAAAQLAADGAPVHTFACDLADAA 70 I G ++GIG A+A+ GA ++ NPE L + L A+ F D+ D+A Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSA 70 Query: 71 QIERYVHAAAQAFGGLDVVVNNAS----GYGHGNDDESWQAGLDVDLMAAVRCNRAAVPY 126 I+ + G +D++VN A G H DE W+A V+ +R+ Y Sbjct: 71 AIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSKY 130 Query: 127 LRQSGNAVILNISSINGQRPTPRAIAYSTAKAALNYYTTTLAAELARERIRVNAIAPGSI 186 + + I+ + S P AY+++KAA +T L ELA IR N ++PGS Sbjct: 131 MMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGST 190 Query: 187 E--FPGGLWEQRSRDEPALY---ARIRDSIPFGGFGQVQHIADAALFLASPQARWITGQV 241 E LW + E + + IP + IADA LFL S QA IT Sbjct: 191 ETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITMHN 250 Query: 242 LAVDGGQSLGV 252 L VDGG +LGV Sbjct: 251 LCVDGGATLGV 261
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 29.8 bits (67), Expect = 0.003 Identities = 20/103 (19%), Positives = 42/103 (40%), Gaps = 10/103 (9%) Query: 44 EYKESIDEMKHADKLSDRILFLEGLPNF---QALGKLRIGENP-----TEMFRCDLALER 95 E + E D +++R+L + G P + I + +EM + + + Sbjct: 52 ELYDHAAE--TVDTIAERLLAIGGQPVATVKEYTEHASITDGGNETSASEMVQALVNDYK 109 Query: 96 EAVVVLREAVAYAETVKDYVSRQLFVDILESEEEHIDWLETQL 138 + + + AE +D + LFV ++E E+ + L + L Sbjct: 110 QISSESKFVIGLAEENQDNATADLFVGLIEEVEKQVWMLSSYL 152
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 59.5 bits (144), Expect = 3e-11 Identities = 25/134 (18%), Positives = 47/134 (35%), Gaps = 5/134 (3%) Query: 498 RILLVEDNPVNLLVAQKLLGVLGFEADTATDGEAALSSMESTRYDMVFMDCQMPVLDGYA 557 IL+ +D+ V + L G++ ++ + + D+V D MP + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 558 ATRRWRAMETESGGRPIPIVAMTANAMAGDRERCLAAGMDDYLSKPVAREQLNACLQRWL 617 R + + +P++ M+A + G DYL KP +L + R L Sbjct: 65 LLPRIKKARPD-----LPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119 Query: 618 PRQALLPGPSTGAP 631 P Sbjct: 120 AEPKRRPSKLEDDS 133
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 67.5 bits (165), Expect = 6e-14 Identities = 28/133 (21%), Positives = 56/133 (42%), Gaps = 4/133 (3%) Query: 107 RVLIVEDDRSQALFAQSVLHGAGMHAQVEMTAASVPQAIQDYHPDLILMDLHMPELDGIR 166 +L+ +DD + L AG ++ AA++ + I DL++ D+ MP+ + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 167 LTTLIRQQPGQQLLPIVFLTGDPDPERQFEVLDSGADDFLTKPIRPRHLIAAVSN--RIR 224 L I++ + LP++ ++ + + GA D+L KP LI + Sbjct: 65 LLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 225 RARQQALQQAGEQ 237 + R L+ + Sbjct: 123 KRRPSKLEDDSQD 135
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 41.4 bits (97), Expect = 5e-06 Identities = 32/137 (23%), Positives = 60/137 (43%), Gaps = 7/137 (5%) Query: 37 LETLAQAFQIQVRTAGAVVTAAQLAYAAGLLLLVPLGDRLERRGLIVGLFVLSALGLLVS 96 L +A F + V TA L ++ G + L D+L + L++ +++ G ++ Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 97 AASHS-FGMLLAGTIVTGASSVAAQILVPFA-ATLAAPQERGRVIGTVMSGLLLGILLAR 154 HS F +L+ + GA + A LV A + RG+ G + S + +G + Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 155 TAAGLLAGVGGWHTVYW 171 G++A H ++W Sbjct: 157 AIGGMIA-----HYIHW 168
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 29.0 bits (65), Expect = 0.048 Identities = 16/65 (24%), Positives = 24/65 (36%), Gaps = 10/65 (15%) Query: 354 PASLRAAAQAIEAARAHG-PVLVCCALGYSRSAASVVTWLV------LSQRAASISEAMA 406 PA LR I+AA + G V +C + + L+ S A SI A + Sbjct: 480 PAILRLVDMVIKAAHSEGKWVGMCGEMA---GDEVAIPLLLGLGLDEFSMSATSILPARS 536 Query: 407 CVRAA 411 + Sbjct: 537 QLLKL 541
>cloacin#Cloacin signature. Length = 551 Score = 34.7 bits (79), Expect = 8e-04 Identities = 17/49 (34%), Positives = 21/49 (42%), Gaps = 3/49 (6%) Query: 448 GTPWASYHEIRAPNTHHHDSTGSSCGGGGDGGDGGGGDSGGDGGGGCGG 496 G+ W+S + P S GG G G GG G+SGG G G Sbjct: 36 GSGWSSENN---PWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNL 81 Score = 32.8 bits (74), Expect = 0.003 Identities = 14/41 (34%), Positives = 20/41 (48%) Query: 461 NTHHHDSTGSSCGGGGDGGDGGGGDSGGDGGGGCGGCGGGG 501 ++ ++ G S G GG G G+ GG+G G G GG Sbjct: 40 SSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGN 80 Score = 31.2 bits (70), Expect = 0.009 Identities = 14/38 (36%), Positives = 18/38 (47%) Query: 465 HDSTGSSCGGGGDGGDGGGGDSGGDGGGGCGGCGGGGD 502 ++ G G G G G G +GG G GG G GG+ Sbjct: 43 NNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGN 80 Score = 30.8 bits (69), Expect = 0.015 Identities = 19/62 (30%), Positives = 22/62 (35%), Gaps = 18/62 (29%) Query: 458 RAPNTHHHDSTGSSCGGGGDGGDGGGGDSG------------------GDGGGGCGGCGG 499 R NT H ++G+ GG G GGG G GGG G GG Sbjct: 7 RGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGG 66 Query: 500 GG 501 G Sbjct: 67 GN 68
>ICENUCLEATIN#Ice nucleation protein signature. Length = 1258 Score = 994 bits (2571), Expect = 0.0 Identities = 942/1306 (72%), Positives = 1056/1306 (80%), Gaps = 48/1306 (3%) Query: 1 MNREKVLALRTCTNNMSDHCGLIWPLSGIVECRHWQPSIKQENGLTGLLWGQGTNAHLNM 60 M +KVL LRTC NNM+DH G+IWPLSGIVEC++W+P ENGLTGL+WG+G+++ L++ Sbjct: 1 MKEDKVLILRTCANNMADHGGIIWPLSGIVECKYWKPVKGFENGLTGLIWGKGSDSPLSL 60 Query: 61 HADAHWVVCMVDTADIIWLGEEGMIKFPRAEVVYAGNRAGAMSCIAAGIEQHSPPKPEPP 120 HADA WVV VD + I + G IKFPRAEV++ G + AM I + Sbjct: 61 HADARWVVAEVDADECIAIETHGWIKFPRAEVLHVGTKTSAMQFILHHRADYV------- 113 Query: 121 ADSVIAAEFTPKAAHAQFTAPIVESGAHSTAPLPSPPNGIGPQAAQPSNAILRTREIATY 180 + + P + + T + + Q Q T EIATY Sbjct: 114 --ACTEMQAGPGSPDVTSEVKVGNRSLPVTDDIDATIESGSTQPTQ-------TIEIATY 164 Query: 181 GSTLTGADQSQLIAGYGSTETAGNGSELIAGYGSTGVAGSDSTIVAGYGSSQTAGGGSTL 240 GSTL+G QSQLIAGYGSTETAG+ S LIAGYGSTG AG+DST+VAGYGS+QTAG S+ Sbjct: 165 GSTLSGTHQSQLIAGYGSTETAGDSSTLIAGYGSTGTAGADSTLVAGYGSTQTAGEESSQ 224 Query: 241 TAGYGSTQTARNGSELTAGYGSTETAGADSSLIAGYGSTQTSGGDSSLTAGYGSTQTAQN 300 AGYGSTQT GS+LTAGYGST TAG DSSLIAGYGSTQT+G DSSLTAGYGSTQTAQ Sbjct: 225 MAGYGSTQTGMKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQK 284 Query: 301 GSDLTAGYGSTSTAGTDSSLIAGYGSTQTSGGESSLTAGYGSTQTAQDGSDLTAGYGSTG 360 GSDLTAGYGST TAG DSSLIAGYGSTQT+G ES+ TAGYGSTQTAQ GSDLTAGYGSTG Sbjct: 285 GSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTG 344 Query: 361 TAGADSSLIAGYGSTQTSGNDSSLTAGYGSTQTARTGSDLTAGYGSTSTAGADSTLIAGY 420 TAG DSSLIAGYGSTQT+G DSSLTAGYGSTQTA+ GSDLTAGYGST TAGADS+LIAGY Sbjct: 345 TAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGY 404 Query: 421 GSTQTSGGDSSLTAGYGSTQTARKGSDLTTGYGSTSTAGADSTLIAGYGSTQTSGSESSL 480 GSTQT+G +S+ TAGYGSTQTA+KGSDLT GYGST TAG DS+LIAGYGSTQT+G +SSL Sbjct: 405 GSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSL 464 Query: 481 TAGYGSTQTARKGSDLTAGYGSTSTAGADSTLIAGYGSTQTSGGESSLTAGYGSTQTARK 540 TAGYGSTQTA+KGSDLTAGYGSTSTAG +S+LIAGYGSTQT+G S+LTAGYGSTQTA+ Sbjct: 465 TAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGSTQTAQN 524 Query: 541 GSDLTAGYGSTSTAGGDSTLVAGYGSTQTSGGDSSLTAGYGSTQTARSGSDLTTGYGSTS 600 SDL GYGSTSTAG +S+L+AGYGSTQT+ +S LTAGYGSTQTAR GSDLT GYGST Sbjct: 525 ESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLTAGYGSTG 584 Query: 601 TAGGESTLIAGYGSTQTSGNASSLTAGYGSTQTARSGSDLTTGYGSTSTAGADSTLIAGY 660 TAG +S++IAGYGSTQT+ SSLTAGYGSTQTAR S LTTGYGSTSTAGADS+LIAGY Sbjct: 585 TAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGY 644 Query: 661 GSTQTSGGESSLTAGYGSTQTARKGSDLTTGYGSTSTAGADSTLIAGYGSTQTAGGESSL 720 GSTQT+G S LTAGYGSTQTA++GSDLT GYGSTSTAGADS+LIAGYGSTQTAG S L Sbjct: 645 GSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQTAGYNSIL 704 Query: 721 TAGYGSTQTARKGSDLTAGYGSTSTAGSDSSLIAGYGSTQTAGFKSILTTGYGSTQTAQE 780 TAGYGSTQTA++GSDLT+GYGSTSTAG+DSSLIAGYGSTQTA + S LT GYGSTQTA+E Sbjct: 705 TAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHSSLTAGYGSTQTARE 764 Query: 781 GSLLTAGYGSSSTAGSDSSLIAGYGSTQTAGFKSILTAGYGSTQTAQERSTLTTGYGSTS 840 S+LT GYGS+STAG+DSSLIAGYGSTQTAG+ SILTAGYGSTQTAQERS LTTGYGSTS Sbjct: 765 QSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTAGYGSTQTAQERSDLTTGYGSTS 824 Query: 841 TAGHDSTLIAGYGSTQTAGYKSILTTGYGSTQTAQESSSLIAGYGSSSMAGPDSSLIAGY 900 TAG DS+LIAGYGSTQTAGY SILT GYGSTQTAQE+S L GYGS+S AG DSSLIAGY Sbjct: 825 TAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYDSSLIAGY 884 Query: 901 GSTQTAGYDSFLTAGYGSTQTAQSSSWLITGYGSTSTASFQSSLIAGYGSTQTAGYESTL 960 GSTQTAGY+S LTAGYGSTQTAQ +S L TGYGSTSTA ++SSLIAGYGSTQTA ++STL Sbjct: 885 GSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYESSLIAGYGSTQTASFKSTL 944 Query: 961 TAGYGSTQTAQEISWLTTGYGSTQTAGHGSILTAGYGSNSTAGYESTLIAGYGSTQTAGY 1020 AGYGS+QTA+E S LT GYGST AG+ S L AGYGS TAGY+STL AGYGSTQTA + Sbjct: 945 MAGYGSSQTAREQSSLTAGYGSTSMAGYDSSLIAGYGSTQTAGYQSTLTAGYGSTQTAEH 1004 Query: 1021 ESTLTAGYGSTLTALENSSLTAGYGSTEIAGFSSTLIAGYGSSQTAGGDSTLTAGYGSTL 1080 STLTAGYGST TAG DS+L AGYGS+L Sbjct: 1005 SSTLTAGYGST--------------------------------ATAGADSSLIAGYGSSL 1032 Query: 1081 MALDNSTLTAGYGSTETAGQDSSLIAGYGSNLTSGVRSYLTAGYGSNQIASYGSSLIAGH 1140 + S LTAGYGST +G S L AGYGS+L SG RS LTAGYGSNQIAS+ SSLIAG Sbjct: 1033 TSGIRSFLTAGYGSTLISGLRSVLTAGYGSSLISGRRSSLTAGYGSNQIASHRSSLIAGP 1092 Query: 1141 ESTQIAGHRSMLIAGKLSSQTAGSRSTLIAGRGSIQTAGDRSKLIAGADSTQIAGDRSKL 1200 ESTQI G+RSMLIAGK SSQTAG RSTLI+G S+Q AG+R KLIAGADSTQ AGDRSKL Sbjct: 1093 ESTQITGNRSMLIAGKGSSQTAGYRSTLISGADSVQMAGERGKLIAGADSTQTAGDRSKL 1152 Query: 1201 LAGSNSFLTAGDRSKLTAGDDCTLMAGDRSKLTAGKNSILTAGANSRLIGSLGSTLTGGE 1260 LAG+NS+LTAGDRSKLTAG+DC LMAGDRSKLTAG NSILTAG S+LIGS GSTLT GE Sbjct: 1153 LAGNNSYLTAGDRSKLTAGNDCILMAGDRSKLTAGINSILTAGCRSKLIGSNGSTLTAGE 1212 Query: 1261 DSVLIFRCWDGKRYTNIIAKTGEEGVEADIAYQVDDDKNVVEKFDD 1306 +SVLIFRCWDGKRYTN++AKTG+ G+EAD+ YQ+D+D N+V K ++ Sbjct: 1213 NSVLIFRCWDGKRYTNVVAKTGKGGIEADMPYQMDEDNNIVNKPEE 1258
>DNABINDNGFIS#DNA-binding protein FIS signature. Length = 98 Score = 114 bits (287), Expect = 3e-37 Identities = 38/74 (51%), Positives = 55/74 (74%) Query: 16 KSPLREHVAQSVRRYLRDLDGSDADDVYEIVLREMEIPLFVEVLNHCEGNQSRAAAMLGI 75 + PLR+ V Q+++ Y L+G D +D+YE+VL E+E PL V+ + GNQ+RAA M+GI Sbjct: 24 QKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGI 83 Query: 76 HRATLRKKLKEYGL 89 +R TLRKKLK+YG+ Sbjct: 84 NRGTLRKKLKKYGM 97
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 41.0 bits (96), Expect = 2e-05 Identities = 29/201 (14%), Positives = 66/201 (32%), Gaps = 19/201 (9%) Query: 467 QRARRQLSAQQNLLAQWQSDLESMRPVVEDSDLFRRIEFEGFDQAT-GDEAEFIGLVEQV 525 + + L + ++Q S+ + F + + L+++ Sbjct: 137 LKTQSSLLQARLEQTRYQILSRSIELNKLPELKLP--DEPYFQNVSEEEVLRLTSLIKEQ 194 Query: 526 ESELRGHYEQIRTAVSQIEATLATTPARFAALRLQVAITQAQ-ADYQALLER---LKSQG 581 S + Q + + A T AR + +++ D+ +LL + K Sbjct: 195 FSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAV 254 Query: 582 VESPDQYAALVARRDELQKELKRLDAGLHEQAGYIQQAEQ-----VLEELTQLRHEISES 636 +E ++Y V + +L+++++ + Q Q +L++L Q I Sbjct: 255 LEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLL 314 Query: 637 RKDFITEINQRAGNRIRLSLS 657 + A N R S Sbjct: 315 T-------LELAKNEERQQAS 328 Score = 36.0 bits (83), Expect = 7e-04 Identities = 30/187 (16%), Positives = 57/187 (30%), Gaps = 13/187 (6%) Query: 371 RNRFPVTVLSQKQIYALAEQRGYLLELLDRQPQVDKAQWQRRFDAMRQRFLGLRAQARQL 430 N+ P L + + + L + Q + WQ + L + + Sbjct: 162 LNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQ--FSTWQNQKYQKELN---LDKKRAER 216 Query: 431 APDLSQRPALEAELRDTERKLKALE--LSHHASSLQAYQRARRQLSAQQNLLAQWQSDLE 488 L++ E R + +L L A + A + N L ++S LE Sbjct: 217 LTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLE 276 Query: 489 SMRPVVEDSDLFRRIEFEGFDQATGDE-AEFIGLVEQVESEL-----RGHYEQIRTAVSQ 542 + + + ++ + F D+ + + + EL R IR VS Sbjct: 277 QIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSV 336 Query: 543 IEATLAT 549 L Sbjct: 337 KVQQLKV 343
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 34.0 bits (77), Expect = 0.002 Identities = 25/122 (20%), Positives = 42/122 (34%), Gaps = 1/122 (0%) Query: 125 LPGAVVVSP-APASSSATATASSATATATTTNGVSAPRTSQADGMPVDPAATNAANASNA 183 LPG A S+ T T T+ ++ + A G P P A A + Sbjct: 138 LPGFDNTPKVTDAPSTVLPTEKPTLFTKLTSEQLTTAQPDDAPGTPAQPLTPLVAEAQSK 197 Query: 184 AAGEAPPVATAATAPNAAATATTQPAARSTRSQTHSPAWTLQFDRIVAEQVQALTLRQLQ 243 A + P A A TQP +P + ++ + +++ + T + Q Sbjct: 198 AEVISTPSPVTAAASPLITPHQTQPLPTVAAPVLSAPLGSHEWQQSLSQHISLFTRQGQQ 257 Query: 244 IA 245 A Sbjct: 258 SA 259
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 38.1 bits (88), Expect = 6e-05 Identities = 15/91 (16%), Positives = 33/91 (36%), Gaps = 3/91 (3%) Query: 171 LRGRVALLTGGRVKIGYQAGLKLLRAGAELIVTTRFPRDSAARYAEEPDFAEWGHRLQVF 230 + G++A +TG IG L GA + + + F Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHI---AAVDYNPEKLEKVVSSLKAEARHAEAF 62 Query: 231 GLDLRHTPSVEAFCSQLLATRTRLDFIINNA 261 D+R + +++ +++ +D ++N A Sbjct: 63 PADVRDSAAIDEITARIEREMGPIDILVNVA 93
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 38.7 bits (90), Expect = 1e-06 Identities = 9/35 (25%), Positives = 15/35 (42%) Query: 20 PGTQLYGFKVLGDAGNGRDSWMIKAVQHVANLHAR 54 P L KVL G+G+ W+I+ + + Sbjct: 108 PEADLLIIKVLNKQGSGQYDWIIQGIYYAIEQKVD 142
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 30.2 bits (68), Expect = 0.008 Identities = 9/16 (56%), Positives = 9/16 (56%) Query: 6 IERETGPNPQWAVIWL 21 I E PNP WA I L Sbjct: 432 IHIEVPPNPFWASIGL 447
>PF06580#Sensor histidine kinase Length = 349 Score = 157 bits (398), Expect = 4e-47 Identities = 70/303 (23%), Positives = 128/303 (42%), Gaps = 17/303 (5%) Query: 59 LWLALAVSVLLCVLRPSLSRLPPRLGGLAALSIAAVVAMLGAGIVHGLYAVLDQAPLGPL 118 + L L + + R +L L L V+ M+ ++ +L P+ Sbjct: 51 MGLVLTHAYRSFIKRQGWLKLNMGQIILRVLPACVVIGMVWFVANTSIWRLLAFINTKPV 110 Query: 119 VGFWRFTLGSAATVVLIT-ALALRYFYVS----------DRWEAQVQANARAEADALQAR 167 L VV++T +L YF D+W+ A A+ AL+A+ Sbjct: 111 AFTLPLALSIIFNVVVVTFMWSLLYFGWHFFKNYKQAEIDQWKMASMAQ-EAQLMALKAQ 169 Query: 168 IRPHFLFNSMNLIASLLRRDPVVAEQAVLDLSDLFRAALGAGEG-VSTLRAECELAERYL 226 I PHF+FN++N I +L+ DP A + + LS+L R +L +L E + + YL Sbjct: 170 INPHFMFNALNNIRALILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYL 229 Query: 227 AIESLRLGDRLQVRWHKQEPLPWALPMPRLVLQPLVENAVLHGVSRMPEGGTLYLSLRQR 286 + S++ DRLQ + + +P +++Q LVEN + HG++++P+GG + L + Sbjct: 230 QLASIQFEDRLQFENQINPAI-MDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKD 288 Query: 287 GSQLQIRIVNPAPQPGTQAPLVVAGAGHAQASISHRLAFQFGAGARMAAGWSEGYYACEI 346 + + + N G ++ RL +G A++ +G + Sbjct: 289 NGTVTLEVENTGSLALKNTKE---STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMV 345 Query: 347 TLP 349 +P Sbjct: 346 LIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.9 bits (158), Expect = 3e-14 Identities = 30/137 (21%), Positives = 51/137 (37%), Gaps = 6/137 (4%) Query: 1 MTATQVRVLIADDEPLARERLRLLLGEHLHVQVVGEAENGEQVLQLCEQQQPDLVLLDIA 60 MT +L+ADD+ R L L + + N + + DLV+ D+ Sbjct: 1 MTGA--TILVADDDAAIRTVLNQALSRAGYDVRI--TSNAATLWRWIAAGDGDLVVTDVV 56 Query: 61 MPGVDGLETARLLRQRPQPPAVVFCTAYD--QHALSAFDAAALDYLMKPVRPERLAAALQ 118 MP + + +++ V+ +A + A+ A + A DYL KP L + Sbjct: 57 MPDENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116 Query: 119 RVATYLAGRTPSLAPAA 135 R R L + Sbjct: 117 RALAEPKRRPSKLEDDS 133
>BCTLIPOCALIN#Bacterial lipocalin signature. Length = 171 Score = 50.4 bits (120), Expect = 3e-10 Identities = 29/117 (24%), Positives = 52/117 (44%), Gaps = 1/117 (0%) Query: 33 DLSKIMGTWYVIARMPNPVERGHVASRDEYTLVEDGKVAVRYRYREGFEEPEKEVNARAS 92 +L+ +G WY +AR+ + ERG EY + DG ++V R + KE +A Sbjct: 30 ELNNYLGKWYEVARLDHSFERGLSQVTAEYRVRNDGGISVLNRGYSEEKGEWKEAEGKAY 89 Query: 93 VDADSGNRDWRVWFYKVIPAKQRILEIAPDG-SWMLISYPGRDLAWIFARKPDMSRD 148 S + +V F+ + E+ + S+ +S P + W+ +R P + R Sbjct: 90 FVNGSTDGYLKVSFFGPFYGSYVVFELDRENYSYAFVSGPNTEYLWLLSRTPTVERG 146
>BICOMPNTOXIN#Staphylococcal bi-component toxin signature. Length = 315 Score = 31.0 bits (70), Expect = 0.005 Identities = 11/44 (25%), Positives = 21/44 (47%) Query: 231 QIVYAPREQQDANDYSDMLGYTTVRKKNKSQTSGKQSSVSYSET 274 I Y P+ + ++ + S LGY + + G S +YS++ Sbjct: 122 LINYLPKNKIESTNVSQTLGYNIGGNFQSAPSLGGNGSFNYSKS 165
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 115 bits (288), Expect = 4e-33 Identities = 77/253 (30%), Positives = 122/253 (48%), Gaps = 16/253 (6%) Query: 6 KVVLITGAARRIGAQIATTLHGAGYRVALHAHRSGDALAARVAALCAQRAGSACALQADL 65 K+ ITGAA+ IG +A TL G +A + + L V++L A+ A A A AD+ Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIA-AVDYNPEKLEKVVSSLKAE-ARHAEAFPADV 66 Query: 66 RTPEAPAQLVDACVAAFGRLDAVVNNASAFYPTVLGEATPAQWDELFAVNARAPFFIAQA 125 R A ++ G +D +VN A P ++ + +W+ F+VN+ F +++ Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 126 AAAQLRAHH-GAIVNLTDLHAEQPMRQHPLYGASKSALEMLTRSLALELAPQ-VRVNAVA 183 + + G+IV + A P Y +SK+A M T+ L LELA +R N V+ Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 184 PGAI-------LWPEDGKADAAKQALLAR----TPLARIGTPEEVAEAVRWLLDD-ASFI 231 PG+ LW ++ A+ + L PL ++ P ++A+AV +L+ A I Sbjct: 187 PGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHI 246 Query: 232 TGHTLRVDGGRRL 244 T H L VDGG L Sbjct: 247 TMHNLCVDGGATL 259
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 33.5 bits (76), Expect = 0.002 Identities = 9/35 (25%), Positives = 12/35 (34%) Query: 27 ADRVASPGEGAFPPAPTPAPTPAPTPAPTPAPAPT 61 A+ +A G + TP P P AP Sbjct: 452 AEELAKLRAGKASDSQTPDAKPGNKAVPGKGQAPQ 486
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 45.0 bits (106), Expect = 1e-07 Identities = 54/273 (19%), Positives = 89/273 (32%), Gaps = 44/273 (16%) Query: 15 MSARAVRTAAVCVLLVLLAVQGVRLVWLLVTPLG----------------PLGTAQG--- 55 +S +R +L++L Q + W + P P+ Sbjct: 9 LSPSVIRRILFYLLMLLFCQQLAMIFWRIGLPDNAPVSSVQITPAQARQQPVTLNDFTLF 68 Query: 56 --ATTAAPLPALQRDVFFRAPADSGDLGLVLHGVRVGG--ADSAAYLSTGDGRQGAYRIG 111 + AL P + L L L GV G + S A +S D Q + + Sbjct: 69 GVSPEKNKAGALDASQMSNLPPST--LNLSLTGVMAGDDDSRSIAIISK-DNEQFSRGVN 125 Query: 112 DAV-GPGLTLQAIATDHVMVRAGSALRRLPLIEHAAASAAITAPLPASGAPAAAAAVASN 170 + V G + +I D V+++ L L SG+ A Sbjct: 126 EEVPGYNAKIVSIRPDRVVLQYQGRYEVLGLYSQ-----------EDSGSDGVPGA---Q 171 Query: 171 VGARTAAAGTTAVDPQQLLRTTGLRANADGGGFTVMPRGDDALLRQAGLAPGDVLTQLNG 230 V + +T + + + + + G+ + P + GL D+ LNG Sbjct: 172 VNEQLQQRASTTM--SDYVSFSPIMNDNKLQGYRLNPGPKSDSFYRVGLQDNDMAVALNG 229 Query: 231 RTL-DAEHLHELQDELRDGQTATLTYRRDGQTH 262 L DAE + + + D TLT RDGQ Sbjct: 230 LDLRDAEQAKKAMERMADVHNFTLTVERDGQRQ 262
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 376 bits (967), Expect = e-123 Identities = 208/684 (30%), Positives = 329/684 (48%), Gaps = 58/684 (8%) Query: 4 VRRPWLLSATLLLALPSLTMLPLHAADAPAVRMQDVDLRAFIQDVSRATGITFIVDTRVQ 63 V R + L+ LL +L P A + + D++ FI VS+ T I+D V+ Sbjct: 6 VIRSFSLT---LLIFAALLFRPAAAEEFS-ASFKGTDIQEFINTVSKNLNKTVIIDPSVR 61 Query: 64 GSVNVARAQAMSEADLLGMLLAVLRANGLIAVSSGPSTYRIIPDDTAAQQPG-----SAA 118 G++ V ++E L+VL G ++ +++ A +A Sbjct: 62 GTITVRSYDMLNEEQYYQFFLSVLDVYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAP 121 Query: 119 SGNLGFATQVFTLQRVDARSAAEILKPLVGRGGVIMAM--PQGNSLLIADYADNLRRIRG 176 T+V L V AR A +L+ L GV + N LL+ A ++R+ Sbjct: 122 GIGDEVVTRVVPLTNVAARDLAPLLRQLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLT 181 Query: 177 LVAQIDTDR-AAIDTVTLRNSSAQELARTLTTLF----GQAGERSAVLSVLPVESSNSLI 231 +V ++D ++ TV L +SA ++ + +T L A S V +V+ E +N+++ Sbjct: 182 IVERVDNAGDRSVVTVPLSWASAADVVKLVTELNKDTSKSALPGSMVANVVADERTNAVL 241 Query: 232 VRGDPALVQRVVRTALDLDGRAERRGDVSVVRLQHASAEQLLPVLQQLVGQTPGNEAEPG 291 V G+P QR++ LD + +G+ V+ L++A A L+ VL + T +E + Sbjct: 242 VSGEPNSRQRIIAMIKQLDRQQATQGNTKVIYLKYAKASDLVEVLTG-ISSTMQSEKQAA 300 Query: 292 QETRPTAVDVAASAGAAQAQVIAPAAGKRPVIVRYPGSNALIINADPETQRALMDVIRQL 351 + ++ A +NALI+ A P+ L VI QL Sbjct: 301 KPVAALDKNIIIKAH--------------------GQTNALIVTAAPDVMNDLERVIAQL 340 Query: 352 DVHREQVLVEAIVVEISDTAAKRLGVQLLLAGRNGTVPLLATQYSGAAPGIVPLAAAAAG 411 D+ R QVLVEAI+ E+ D LG+Q A +N + TQ++ + I A A Sbjct: 341 DIRRPQVLVEAIIAEVQDADGLNLGIQW--ANKNAGM----TQFTNSGLPISTAIAGANQ 394 Query: 412 TRSNNGEDDSVLEQARNVAAQSLLGLSGGLIGLAGQSNDAVFGMIIDAVKSDTGSNLLST 471 + S+ S L G+ Q N + M++ A+ S T +++L+T Sbjct: 395 YNKDGTVSSSLA---------SALSSFNGIAAGFYQGN---WAMLLTALSSSTKNDILAT 442 Query: 472 PSIMTLDNEQARILVGQEVPITTGEVLGAANDNPFRTIQRQDVGVELEVRPQINTAGGIT 531 PSI+TLDN +A VGQEVP+ TG + DN F T++R+ VG++L+V+PQIN + Sbjct: 443 PSIVTLDNMEATFNVGQEVPVLTGSQTTS-GDNIFNTVERKTVGIKLKVKPQINEGDSVL 501 Query: 532 LAIKQEVSAIAGPVSTQSSEL--VFNKRQIETRVVVENGAIVALGGLLDQNDRQTVEKVP 589 L I+QEVS++A S+ SS+L FN R + V+V +G V +GGLLD++ T +KVP Sbjct: 502 LEIEQEVSSVADAASSTSSDLGATFNTRTVNNAVLVGSGETVVVGGLLDKSVSDTADKVP 561 Query: 590 LLGDVPGLGALFRHKSRNRDKTNLMVFIRPTIIRDAADAQRMTAPRYNYLRDRQLADGDP 649 LLGD+P +GALFR S+ K NLM+FIRPT+IRD + ++ ++ +Y D Q Sbjct: 562 LLGDIPVIGALFRSTSKKVSKRNLMLFIRPTVIRDRDEYRQASSGQYTAFNDAQSKQRGK 621 Query: 650 EAALDALVRDYLRAQPPQLPASAP 673 E L +D L P Q A+ Sbjct: 622 ENNDAMLNQDLLEIYPRQDTAAFR 645
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 342 bits (878), Expect = e-117 Identities = 170/405 (41%), Positives = 238/405 (58%), Gaps = 10/405 (2%) Query: 1 MAKFDYTVLDLHGRNRHGVISADSVRSARSLLEQRQWVPLRVEPAAATTP---------M 51 MA++ Y LD G+ G ADS R AR LL +R VPL V+ Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 52 RAARFSGKDLVLFTRQLATLVDTA-PLEEALRTIGTQSERRGVRAVTGQTHALVVEGFRL 110 R R S DL L TRQLATLV + PLEEAL + QSE+ + + + V+EG L Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 111 SDAMARQGTAFPPLYRAMVAAGESAGALPQVLERLADLLERQAQVRSKLQSALVYPAALA 170 +DAM +F LY AMVAAGE++G L VL RLAD E++ Q+RS++Q A++YP L Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 171 MTAGVVVIVLMTFVVPKVVDQFDSMGRALPWLTRAVIALSQFLLHAGIPLLVAGVIAAVV 230 + A VV +L++ VVPKVV+QF M +ALP TR ++ +S + G +L+A + + Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMA 240 Query: 231 AVQVRKRPPVRLAIDRAILRAPLLGRLLRDLHAARMARTLAIMVNSGLPLMEGLMIAART 290 + ++ R++ R +L PL+GR+ R L+ AR ARTL+I+ S +PL++ + I+ Sbjct: 241 FRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 291 VDNHALRLATDSMVTAIREGGSLGAAMKRAGVFPPTLLYMASSGENSGRLAPMLERAADY 350 + N R A+REG SL A+++ +FPP + +M +SGE SG L MLERAAD Sbjct: 301 MSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADN 360 Query: 351 LEREFESFTTAAMSLLEPLIIVLLGGVVAVIVLSILLPILQFNTL 395 +REF S T A+ L EPL++V + VV IVL+IL PILQ NTL Sbjct: 361 QDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTL 405
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 182 bits (462), Expect = 3e-62 Identities = 65/134 (48%), Positives = 91/134 (67%), Gaps = 3/134 (2%) Query: 17 RGFTLVELMVVIVIIGLLATVVMINVMPSQDRAMVEKARADVAVLEQALETYRLDNLTYP 76 RGFTL+E+MVVIVIIG+LA++V+ N+M ++++A +KA +D+ LE AL+ Y+LDN YP Sbjct: 8 RGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDNHHYP 67 Query: 77 STEQGLQALLSAPGGLSRPERYRQGGYIRRLPEDPWGHAYQYRRPGRSGGFDVYSFGADG 136 +T QGL++L+ AP Y + GYI+RLP DPWG+ Y PG G +D+ S G DG Sbjct: 68 TTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDLLSAGPDG 127 Query: 137 AEGGDADNADIGNW 150 G + DI NW Sbjct: 128 EMGTE---DDITNW 138
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 40.7 bits (95), Expect = 5e-07 Identities = 14/74 (18%), Positives = 31/74 (41%), Gaps = 1/74 (1%) Query: 13 GFTLLEVLAVLVITALASTVVLLTLPDT-QRTLPDQADALATALSHARDEAILSLRMTEV 71 GFTLLE++ +L++ +++ +VLL P + + L + + + + V Sbjct: 5 GFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQTLARFEAQLRFVQQRGLQTGQFFGV 64 Query: 72 VLSAGGYAFRRQAR 85 + + F Sbjct: 65 SVHPDRWQFLVLEA 78
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 31.4 bits (71), Expect = 5e-04 Identities = 19/59 (32%), Positives = 34/59 (57%), Gaps = 4/59 (6%) Query: 3 RRADTQAGFSLLELLVALAIFG-MAVVGLLNLSGESTRTAVILEERALAAVVAENQAIE 60 R D Q GF+LLE++V + I G +A + + NL G + ++A++ +VA A++ Sbjct: 2 RATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADK---QKAVSDIVALENALD 57
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 32.2 bits (73), Expect = 5e-04 Identities = 12/48 (25%), Positives = 24/48 (50%) Query: 1 MMRLRRAAGFTLIELLVALAVFALVAAAAVGVLRQSIEQRAAVQARLQ 48 M + GFTL+E++V + + ++A+ V L + E+ +A Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSD 48
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 30.6 bits (69), Expect = 0.009 Identities = 22/94 (23%), Positives = 30/94 (31%), Gaps = 13/94 (13%) Query: 22 DAQGH-VHVHGTAASTPPAARTVLVVPGTQVH-LRWLALPGRSPAQSLAAARLQLAEHLA 79 D GH HV GT A+T V V P + ++ L G + E Sbjct: 82 DYNGHGTHVAGTIAATENENGVVGVAPEADLLIIKVLNKQGSGQYDWIIQGIYYAIEQKV 141 Query: 80 ----------SDVSTLHVVIAANAQADGTRLVAA 103 DV LH + A A ++ A Sbjct: 142 DIISMSLGGPEDVPELHEAV-KKAVASQILVMCA 174
>BONTOXILYSIN#Bontoxilysin signature. Length = 1196 Score = 28.7 bits (64), Expect = 0.027 Identities = 17/73 (23%), Positives = 29/73 (39%), Gaps = 8/73 (10%) Query: 163 DHNSWPIGTLTASKV----ITAGGRTFDLWEGFNSGAGYYVYTFIPTGTAGQATLKTSGS 218 H + I L A T + D + +S VY+F+ + T+K G Sbjct: 495 THTALSINYLQAQITNNENFTL---SSDFSKVVSSKDKSLVYSFLDNLMSYLETIKNDGP 551 Query: 219 LNVDAKPFLNWLQ 231 ++ D K + WL+ Sbjct: 552 IDTDKK-YYLWLK 563
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 40.1 bits (94), Expect = 2e-05 Identities = 17/33 (51%), Positives = 22/33 (66%) Query: 348 LAGLTRVPAEIFGVGDRIGSIAVGKQADLVLWD 380 +A T PA G+ IGS+ VGK+ADLVLW+ Sbjct: 406 IAKYTINPAIAHGLSHEIGSLEVGKRADLVLWN 438
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 36.3 bits (84), Expect = 2e-04 Identities = 23/72 (31%), Positives = 34/72 (47%), Gaps = 12/72 (16%) Query: 41 VLIQHATVLTGTGQRLDDADVLLRDGKVAAVGRG----------LEVPADARRIDGTGKW 90 +I +A +L G AD+ L+DG++AA+G+ + V I G GK Sbjct: 70 TVITNALILDHWGIV--KADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKI 127 Query: 91 VTPGIIDVHSHL 102 VT G +D H H Sbjct: 128 VTAGGMDSHIHF 139 Score = 33.6 bits (77), Expect = 0.002 Identities = 16/35 (45%), Positives = 21/35 (60%) Query: 389 RAIRWLTSNAAKALGIEQQTGALEPGKMGDMVVWN 423 R I T N A A G+ + G+LE GK D+V+WN Sbjct: 404 RYIAKYTINPAIAHGLSHEIGSLEVGKRADLVLWN 438
>PF06580#Sensor histidine kinase Length = 349 Score = 31.8 bits (72), Expect = 0.005 Identities = 20/101 (19%), Positives = 36/101 (35%), Gaps = 23/101 (22%) Query: 304 LVGNAVKY-----TERGQVLVGCRRRPGHAVVEVIDSGIGLNLEHPEDVFQAFRQADPGS 358 LV N +K+ + G++L+ + G +EV ++G Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSL--------------ALKNTK 308 Query: 359 DGLGIGLWIVHRTAETL---GCQVEVRPRPSGGTRFSVTIP 396 + G GL V + L Q+++ + G V IP Sbjct: 309 ESTGTGLQNVRERLQMLYGTEAQIKLSEKQ-GKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.3 bits (71), Expect = 0.003 Identities = 26/162 (16%), Positives = 50/162 (30%), Gaps = 26/162 (16%) Query: 105 TKLEVLGDERTLYPDVVQTLKAAEQLVADGFEVMVYTSDDPILAKRLEEIGCVAVMPLAA 164 + V D+ + + Q L A G++V + ++ + G + V + Sbjct: 4 ATILVADDDAAIRTVLNQALSRA------GYDVRITSNAATLWRWIAAGDGDLVVTDVVM 57 Query: 165 PIGSGLGIQNKYNLLEII--ENAKVPIIVDAGVGTASDAAIAMELGCDGVLMNTAIAGAR 222 P + LL I +P++V + T A A E GA Sbjct: 58 PDENAFD------LLPRIKKARPDLPVLVMSAQNTFMTAIKASE------------KGAY 99 Query: 223 DPILMASAMRKAIEAGREAFLAGRIPRKRYASASSPVDGVIG 264 D + + + I A + + S ++G Sbjct: 100 DYLPKPFDLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVG 141
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 330 bits (849), Expect = e-116 Identities = 130/282 (46%), Positives = 175/282 (62%), Gaps = 1/282 (0%) Query: 1 MAFLDQHPGLGFPAAAGLGLLIGSFLNVVILRLPKRMEWQWRRDAREILELPDI-YEPPP 59 + P L F L+IGSFLNVVI RLP +E +W+ + R D + PP Sbjct: 5 LELAHGLPWLYFSLVFLFSLMIGSFLNVVIHRLPIMLEREWQAEYRSYFNPDDEGVDEPP 64 Query: 60 PGIVVEPSHDPVTGDKLKWWENIPLFSWLMLRGKSRYSGKPISIQYPLVELLTSILCVAS 119 ++V S P + ENIPL SWL LRG+ R PIS +YPLVELLT++L VA Sbjct: 65 YNLMVPRSCCPHCNHPITALENIPLLSWLWLRGRCRGCQAPISARYPLVELLTALLSVAV 124 Query: 120 VWRFGFGWQGFGAIVLSCFLVAMSGIDLRHKLLPDQLTLPLMWLGLVGSMDNLYMPAKPA 179 GW A++L+ LVA++ IDL LLPDQLTLPL+W GL+ ++ ++ A Sbjct: 125 AMTLAPGWGTLAALLLTWVLVALTFIDLDKMLLPDQLTLPLLWGGLLFNLLGGFVSLGDA 184 Query: 180 LLGAAVGYVSLWTVWWLFKQLTGKEGMGHGDFKLLAALGAWCGLKGILPIILISSLVGAV 239 ++GA GY+ LW+++W FK LTGKEGMG+GDFKLLAALGAW G + + ++L+SSLVGA Sbjct: 185 VIGAMAGYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALPIVLLLSSLVGAF 244 Query: 240 LGSIWLFAKGRDRATPIPFGPYLAIAGWVVFFWGNDLVDGYL 281 +G + + ++ PIPFGPYLAIAGW+ WG+ + YL Sbjct: 245 MGIGLILLRNHHQSKPIPFGPYLAIAGWIALLWGDSITRWYL 286
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 380 bits (978), Expect = e-132 Identities = 118/407 (28%), Positives = 219/407 (53%), Gaps = 9/407 (2%) Query: 20 MVPFVWEGTDKRGIKMKGEQPARNANMLRAELRRQGITPLVV-----KTKPKPLFGAA-- 72 M + ++ D +G K +G Q A +A R LR +G+ PL V + G + Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 73 -GKKISSKDIAFFSRQMATMMKSGVPIVGSLEIIGEGHKNPRMKKMVGQIRTDIEGGSSL 131 ++S+ D+A +RQ+AT++ + +P+ +L+ + + + P + +++ +R+ + G SL Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 132 HEAISRHPVQFDDLYRNLVRAGEGAGVLETVLDTVANYKENIEALKGKIKKALFYPAMVM 191 +A+ P F+ LY +V AGE +G L+ VL+ +A+Y E + ++ +I++A+ YP ++ Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 192 AVAIIVSGILLVFVVPQFEDVFKGFGAELPAFTQMIVAASRFMVSYWWLMLLGSIAAIAG 251 VAI V ILL VVP+ + F LP T++++ S + ++ MLL +A Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMA 240 Query: 252 FIFAYKRSPRMRHGMDRLVLKVPVIGQIMHNSSIARFARTTAVTFKAGVPLVEALSIVAG 311 F R + R R +L +P+IG+I + AR+ART ++ + VPL++A+ I Sbjct: 241 FRVML-RQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGD 299 Query: 312 ATGNKVYEEAVLRMRDDVSVGYPVNMAMKQVNLFPHMVVQMTSIGEEAGALDAMLFKVAE 371 N + D V G ++ A++Q LFP M+ M + GE +G LD+ML + A+ Sbjct: 300 VMSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAAD 359 Query: 372 YFEQEVNNAVDALSSLLEPLIMVFIGTIVGGMVIGMYLPIFKLGSVV 418 ++E ++ + L EPL++V + +V +V+ + PI +L +++ Sbjct: 360 NQDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 46.0 bits (109), Expect = 3e-09 Identities = 22/74 (29%), Positives = 39/74 (52%), Gaps = 2/74 (2%) Query: 1 MKKQNGFTLIELMIVVAIIAILAAIALPAYQDYLARSQVSEGLSLASGAKTAVAETYANT 60 KQ GFTL+E+M+V+ II +LA++ +P ++ + +S + A+ + Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDN 63 Query: 61 GAFPATNAAAGLEA 74 +P TN GLE+ Sbjct: 64 HHYPTTN--QGLES 75
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 44.5 bits (105), Expect = 1e-08 Identities = 20/72 (27%), Positives = 38/72 (52%), Gaps = 2/72 (2%) Query: 2 RVRGFTLIELMIVVAVIAILAAIALPAYQDYLVRAQVSEGLSLASGAKVAVEEFHWAKSA 61 + RGFTL+E+M+V+ +I +LA++ +P +A + +S + A++ + Sbjct: 6 KQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDNHH 65 Query: 62 SPSTNIEAGLGS 73 P+T GL S Sbjct: 66 YPTT--NQGLES 75
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 507 bits (1308), Expect = e-180 Identities = 166/474 (35%), Positives = 257/474 (54%), Gaps = 17/474 (3%) Query: 6 SALVVDDERDIRELLVLTLGRMGLRISTAANLAEARELLASNPYDLCLTDMRLPDGNGIE 65 + LV DD+ IR +L L R G + +N A +A+ DL +TD+ +PD N + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 66 LVTEIARQYPQTPVAMITAFGSMDLAVEALKAGAFDFVSKPVDISVLRGLVKHALELNNR 125 L+ I + P PV +++A + A++A + GA+D++ KP D++ L G++ AL R Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 126 DRPAPPPPPLEQASRLLGDSTAMESLRSTIGKVARSQAPVYIVGESGVGKELVARTIHEQ 185 RP+ + L+G S AM+ + + ++ ++ + I GESG GKELVAR +H+ Sbjct: 125 -RPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDY 183 Query: 186 GARAAGPFIPVNCGAIPAELMESEFFGHKKGSFTGAHADKPGLFQAAHGGTLFLDEVAEL 245 G R GPF+ +N AIP +L+ESE FGH+KG+FTGA G F+ A GGTLFLDE+ ++ Sbjct: 184 GKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDM 243 Query: 246 PLQMQVKLLRAIQEKSVRPVGASGETLVDVRILSATHKDLGDLVSDGRFRHDLYYRINVI 305 P+ Q +LLR +Q+ VG DVRI++AT+KDL ++ G FR DLYYR+NV+ Sbjct: 244 PMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVV 303 Query: 306 ELRVPPLRERSGDLPQLAAAIIARLARSHGRPIPLLTQSALDALDTYGFPGNVRELENIL 365 LR+PPLR+R+ D+P L + + + G + Q AL+ + + +PGNVRELEN++ Sbjct: 304 PLRLPPLRDRAEDIPDLVRHFVQQAEK-EGLDVKRFDQEALELMKAHPWPGNVRELENLV 362 Query: 366 ERALALAEDDQISASDLRLPAH---------------GGHRLAASPGSAAIEPREAVVDI 410 R AL D I+ + G ++ + + + D Sbjct: 363 RRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDA 422 Query: 411 DPASSALPSYIEQLERAAIQKALEENRWNKTKTAAQLGITFRALRYKLKKLGME 464 P S + ++E I AL R N+ K A LG+ LR K+++LG+ Sbjct: 423 LPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>BICOMPNTOXIN#Staphylococcal bi-component toxin signature. Length = 315 Score = 32.2 bits (73), Expect = 0.004 Identities = 11/36 (30%), Positives = 17/36 (47%), Gaps = 1/36 (2%) Query: 30 IYQTVAYAF-DDTQHGADLFDLKVQGNIYSRIMNPT 64 + Q + + F D ++ D LK+QG I SR Sbjct: 58 VTQNIQFDFVKDKKYNKDALILKMQGFISSRTTYYN 93
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 31.3 bits (71), Expect = 0.007 Identities = 47/230 (20%), Positives = 76/230 (33%), Gaps = 40/230 (17%) Query: 31 DLAALDAHAAWMRAQLPPGCTLFYAAKANA----EPQILQTLAPYVDGFEAASGGE-LAW 85 DL AL + + +R Q ++ KANA +I + DGF + E + Sbjct: 10 DLQALKQNLSIVR-QAATHARVWSVVKANAYGHGIERIWSAI-GATDGFALLNLEEAITL 67 Query: 86 LHQQQPDAALLFGGPGKLES-ELAQAVRLPDCTVHVESLGELQRLAAIARQIAQPDRRRI 144 + L+ G + E+ RL C VH + AR + + Sbjct: 68 RERGWKGPILMLEGFFHAQDLEIYDQHRLTTC-VHSN---WQLKALQNARL-----KAPL 118 Query: 145 PVFLRMNIAVPGAQTTRLMMGGQPSPFGLDPDDLDAALLQLRASPALELRGFHFHLMSHQ 204 ++L++N + RL G PD + QLRA + H Sbjct: 119 DIYLKVNSGM-----NRL---------GFQPDRVLTVWQQLRAMANVGEMTLMSHFAE-- 162 Query: 205 RDAAAQLHLIAAYLRTVQHWRQRHGLGPLLVNAGGGFGVDYLTPEASFDW 254 A I+ + ++ + L N+ PEA FDW Sbjct: 163 ---AEHPDGISGAMARIEQAAEGLECRRSLSNSAATL----WHPEAHFDW 205
>PF04183#IucA / IucC family Length = 580 Score = 278 bits (712), Expect = 4e-88 Identities = 109/523 (20%), Positives = 190/523 (36%), Gaps = 51/523 (9%) Query: 100 DGHALARSLLQALGSTHAVNPELLAQSDNSVAIT----AALL--RQAQAATPTGDTLIDA 153 D LA++LL L +++ +A+ + T LL R+ +A+ + D Sbjct: 69 DEPVLAQTLLMQLKQVLSMSDATVAEHMQDLYATLLGDLQLLKARRGLSASDLINLNADR 128 Query: 154 EQALLWGHALHPTPKSREGVALAQVLACAPEARAAFALYWFRIDRRLLRVQ---GRDVRA 210 Q LL GH K R G + APE F L+W + R + + D+ Sbjct: 129 LQCLLSGHPKFVFNKGRRGWGKEALERYAPEYANTFRLHWLAVKREHMIWRCDNEMDIHQ 188 Query: 211 TLQ---------------QLSGHDDFY---PCHPWEVQRLRDDPLLQELQARGAITPVGV 252 L Q +G D + P HPW+ Q+ + + A G + +G Sbjct: 189 LLTAAMDPQEFARFSQVWQENGLDHNWLPLPVHPWQWQQKIATDFIADF-AEGRMVSLGE 247 Query: 253 LGEPLRPTSSVRTLYHP--ALAYFLKCSVHVRLTNCVRKNAWYELESAVALTHLLAPSWQ 310 G+ S+RTL + +K + + T+C R + + + L + Sbjct: 248 FGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLASRWLQQVFA 307 Query: 311 ALAAQV-PGFDVMLEPAATSLDVTQFDPALAAADPLATRALAESFGILYRQAPTAAQRAR 369 A V G ++ EPAA + + AA A E G+++R+ P + Sbjct: 308 TDATLVQSGAVILGEPAAGYVSHEGY-----AALARAPYRYQEMLGVIWRENPCRWLKPD 362 Query: 370 WRPQVAAALFTCDAQGHSVAAAALRAHSVRRLDRRTATVLWFRAYAGLLLDGVWSALFQH 429 P + A L CD +A A + R T W +++ ++ L ++ Sbjct: 363 ESPVLMATLMECDENNQPLAGA-----YIDRSGLDAET--WLTQLFRVVVVPLYHLLCRY 415 Query: 430 GIALEPHLQNTVIGFSDGWPTRVWIRDLEGT-KLLAQRWPAARLHGVGERARQSLYYTPE 488 G+AL H QN + +G P RV ++D +G +L+ + +P + + + R Sbjct: 416 GVALIAHGQNITLAMKEGVPQRVLLKDFQGDMRLVKEEFPE--MDSLPQEVRDVTSRLSA 473 Query: 489 QAWNRVAYCALVNNLAEAIFHLSDGDAVLEARLWQCVAEIAARWQQRNGAQPALQGLID- 547 + I L V E R +Q +A + + + +++ L Sbjct: 474 DYLIHDLQTGHFVTVLRFISPLMVRLGVPERRFYQLLAAVLSDYMKKHPQMSERFALFSL 533 Query: 548 GAPLPGKNNLGTRLLQRADRQSDYTALPNPIA----PMHAVQQ 586 P + L L D LPN + P+ V Q Sbjct: 534 FRPQIIRVVLNPVKLTWPDLDGGSRMLPNYLEDLQNPLWLVTQ 576
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 60.6 bits (147), Expect = 3e-12 Identities = 52/156 (33%), Positives = 70/156 (44%), Gaps = 3/156 (1%) Query: 20 LGMPLFLPQVLAELAPSAAI-GWSGVLYVLPTLCTALTASTWGRLADRYGRKRSLLRAQL 78 L MP+ LP +L +L S + G+L L L A G L+DR+GR+ LL + Sbjct: 23 LIMPV-LPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLA 81 Query: 79 GLALGFAIAGFAPTLPWLVVGLIVQGTCGGSLAAANAYLASQPQAGPLARALDWTQYSAR 138 G A+ +AI AP L L +G IV G G + A A AY+A AR + Sbjct: 82 GAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFG 141 Query: 139 LAMVSAPALLGLAVALGPAQALYRALALLPLVAFAL 174 MV+ P L GL P + A A L + F Sbjct: 142 FGMVAGPVLGGLMGGFSPHAPFFAA-AALNGLNFLT 176
>PF04183#IucA / IucC family Length = 580 Score = 151 bits (384), Expect = 2e-41 Identities = 90/384 (23%), Positives = 139/384 (36%), Gaps = 49/384 (12%) Query: 121 DEAACAAAHRGLARDAYA-AQAPHLAQALRAADAAERAYRCDQLASYRD-HPFYPTARAK 178 +A A + L Q + L A+D D+L HP + + + Sbjct: 88 SDATVAEHMQDLYATLLGDLQLLKARRGLSASDLINLNA--DRLQCLLSGHPKFVFNKGR 145 Query: 179 AGLAPAELRAYAPEFAPTFALQWLAIPQAQVSCTSTPPAELWPDLARVGLPAELAQTHQL 238 G L YAPE+A TF L WLA+ + + ++ L P E A+ Q+ Sbjct: 146 RGWGKEALERYAPEYANTFRLHWLAVKREHMIWRCDNEMDIHQLLTAAMDPQEFARFSQV 205 Query: 239 W------------PVHPLVWARLEQDGFALPAGSVRAPLTYLP-----VRPTLSVRTLVP 281 W PVHP W + F A + L S+RTL Sbjct: 206 WQENGLDHNWLPLPVHPWQWQQKIATDFI--ADFAEGRMVSLGEFGDQWLAQQSLRTLTN 263 Query: 282 LQHPH-LHLKLPIPMRTLGALNLRLIKPSTLYDGHWLEQALRRIDAHDAALRGRCVFV-D 339 L +KLP+ + R I + G + L+++ A DA L + Sbjct: 264 ASRRGGLDIKLPLTIYNTSC--YRGIPGRYIAAGPLASRWLQQVFATDATLVQSGAVILG 321 Query: 340 ESHGGHV-------------GQTRHLAYLLRRYPPLDTA---TLVPVAALCALMPDGRPM 383 E G+V L + R P + V +A L + +P+ Sbjct: 322 EPAAGYVSHEGYAALARAPYRYQEMLGVIWRENPCRWLKPDESPVLMATLMECDENNQPL 381 Query: 384 AIHLAETFSGGDLLAWWRDYTELLLAVHLRLWLRYGIALEANQQNSVLVYAPGQPTRLLM 443 A + SG D W +++ L RYG+AL A+ QN L G P R+L+ Sbjct: 382 AGAYIDR-SGLDAETWLTQLFRVVVVPLYHLLCRYGVALIAHGQNITLAMKEGVPQRVLL 440 Query: 444 KDN-DAARIALPQLRAQLPEIDTL 466 KD R+ ++ + PE+D+L Sbjct: 441 KDFQGDMRL----VKEEFPEMDSL 460
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.6 bits (69), Expect = 0.016 Identities = 33/210 (15%), Positives = 61/210 (29%), Gaps = 15/210 (7%) Query: 144 LRLRQLQARRAGLDALVAQAVAAQQQGRLDGTPDSA--LPLYQRVLSLAPDRTDALEGRE 201 L+L L A L + A +Q R S L + L P + E Sbjct: 125 LKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEV 184 Query: 202 DALTDLLAQARHALARDALAEAAALLAAAKRYDAGHADVPSTEGQYHRLMDQRRQRADTL 261 LT L+ + + L A + E R+ R +L Sbjct: 185 LRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLS-RVEKSRLDDFSSL 243 Query: 262 LRRGRLA-PAVRDFTAVLAAEPGDAQAQRG----VERVAAEYAGQATRQAGDFQFDAATQ 316 L + +A AV + + + + +E + F+ + + Sbjct: 244 LHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDK 303 Query: 317 SLQQARALVPSGPSIAAAEQAIARARDAQR 346 L+Q +I +A+ + Q+ Sbjct: 304 -LRQTTD------NIGLLTLELAKNEERQQ 326
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.036 Identities = 19/95 (20%), Positives = 27/95 (28%), Gaps = 8/95 (8%) Query: 470 EAQRQVGSLLKPFVY--LLALASPDRWALSSWVDDSPVTVQLARGKTWSPGNSDNRSHGT 527 + + LLKP + AL S A D+ R W Sbjct: 439 RLRLRGRWLLKPRRAALIEALRSAPALAGCVAFDELREQPVAVRAFPWRKAPGPLEDADV 498 Query: 528 VRLIDALAHSYNQATVRVGMQVGPERVAQLIQVLA 562 +RL D + +Y + Q I V A Sbjct: 499 LRLADYVETTYGTGEAS------AQTTEQAINVAA 527
>BACINVASINC#Salmonella/Shigella invasin protein C signature. Length = 409 Score = 29.1 bits (64), Expect = 0.008 Identities = 24/97 (24%), Positives = 39/97 (40%), Gaps = 6/97 (6%) Query: 69 RETAKAKRQIGDLAAAAAALDQALGLVSGDPAILQERAEVAVLQGDWNASERFAKQAIEL 128 R A+ + GDL + + S A QER+E + Q + + + +A E Sbjct: 315 RIDARKMQMTGDLIMKNSVTVGGIAGASRQYAATQERSEQQISQVNNRVASTASDEARES 374 Query: 129 GSKTGPLCRRHWATIEQARLARGEKENAASAKAQIVG 165 K+ L + T+E ++ ASA A I G Sbjct: 375 SRKSTSLIQEMLKTMESI------NQSKASALAAIAG 405
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 118 bits (298), Expect = 2e-34 Identities = 41/262 (15%), Positives = 86/262 (32%), Gaps = 37/262 (14%) Query: 11 MDERQRLTATLVISLLLHGLLILGVGFAVSEDAPLVPTLDVIFSQTSTPLTPKQADFLAQ 70 +D +R ++S+ +HG ++ G+ + +P P P +A Sbjct: 8 LDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPA----------PAQPISVTMVAP 57 Query: 71 ANQQGGGNHDTAQRPRDSQPGVVPQDRNGLAPQAQRATTVQAPLPTQTRVVSSRRGEQAV 130 A D P P+ P+ + P + Sbjct: 58 A--------DLEPPQAVQPP---PEPVVEPEPEPEPIPEPPKEAPVV------------I 94 Query: 131 PTPQPNPQTDPLSPADAQRVQRDAEMARLAAEVHLRSEQYAKRPNRKFVSASTREYAYAN 190 P+P P+ P ++ +RD + + A+ + +A+++ Sbjct: 95 EKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVA 154 Query: 191 YLRAWVDRAERVGNLNYPDEARRRRLGGKVVITVGVRRDGSVESSRVLVSSGTPVLDAAA 250 + R YP A+ R+ G+V + V DG V++ ++L + + + Sbjct: 155 SGPRALSRN----QPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREV 210 Query: 251 LRVVQLAQPFPPLPRSKDDVDI 272 ++ + P P S V+I Sbjct: 211 KNAMRRWRYEPGKPGSGIVVNI 232
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 73.3 bits (180), Expect = 2e-18 Identities = 28/115 (24%), Positives = 49/115 (42%), Gaps = 2/115 (1%) Query: 15 KVMVIDDSKTIRRTAETLLKREGCEVVTATDGFEALAKIADQQPQIIFVDIMMPRLDGYQ 74 ++V DD IR L R G +V ++ IA ++ D++MP + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 75 TCALIKGNQLFKSTPVIMLSSKDGLFDKARGRIVGSEQYLTKPFTREELLSAIRT 129 IK + PV+++S+++ + G+ YL KPF EL+ I Sbjct: 65 LLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 88.3 bits (219), Expect = 6e-24 Identities = 36/116 (31%), Positives = 57/116 (49%), Gaps = 2/116 (1%) Query: 2 ARIILIEDSPTDRAVFSQWLEKAGHTVVATDNAEEGLELIRSQAPDLVLMDVVLPGMSGF 61 A I++ +D R V +Q L +AG+ V T NA I + DLV+ DVV+P + F Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 QATRALARDQATKDIPVLLVSTKGMETDKAWGLRQGASDYIVKPPREDDLIARIKQ 117 + + + D+PVL++S + +GA DY+ KP +LI I + Sbjct: 64 DLLPRIKKAR--PDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 46.3 bits (110), Expect = 2e-08 Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 3/68 (4%) Query: 84 YGGTFDPIHRGHLAIACAARDALGAQVHLVPAADPPHRPAPGATAAQRTRMLELALADLP 143 Y G+FDPI GHL I L QV++ +P +P + +R + A+A LP Sbjct: 5 YPGSFDPITFGHLDIIERGC-RLFDQVYVAVLRNPNKQPMF--SVQERLEQIAKAIAHLP 61 Query: 144 GLLLDTRE 151 +D+ E Sbjct: 62 NAQVDSFE 69
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 66.2 bits (161), Expect = 3e-15 Identities = 48/212 (22%), Positives = 74/212 (34%), Gaps = 30/212 (14%) Query: 39 LIPLSHHQVMQPPTPKERWLMPITVPATPPPPPLV-----------FPVEVTFKAPSTHT 87 L+ S HQV++ P P + + + PA PP V E + P Sbjct: 32 LLYTSVHQVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAP 91 Query: 88 PVI----ADPVVKQPSVTQTAVVDTAHVALEAVSDTAPTISAPAAPPSSG---------P 134 VI P K V + +E+ + +APA P SS Sbjct: 92 VVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVT 151 Query: 135 VDAGQLHYLSAPAPSYPVAALRAGQQGTVMLRVLVGTDGRPAEVSVQTSSGHRALDLAAR 194 A LS P YP A +G V ++ V DGR V + ++ + + Sbjct: 152 SVASGPRALSRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVK 211 Query: 195 SQVLRSWRFQPAMQNGQAVQAYGLVPVSFSLN 226 + + R WR++P V V + F +N Sbjct: 212 NAM-RRWRYEPGKPGSGIV-----VNILFKIN 237
>PF06580#Sensor histidine kinase Length = 349 Score = 36.0 bits (83), Expect = 4e-04 Identities = 22/102 (21%), Positives = 45/102 (44%), Gaps = 22/102 (21%) Query: 553 LIENAVQHA----PAGSRVVITARTLDENGRASVECRVQDAGSGFAPDDLPRIFDPFFTR 608 L+EN ++H P G ++++ +NG ++E V++ GS + Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGT--KDNGTVTLE--VENTGSLALKNT----------- 307 Query: 609 RRKGTGLGLAIVQRIVEEHKGTIAG--HNSPEGGAVMVMRLP 648 ++ TG GL V+ ++ GT A + +G ++ +P Sbjct: 308 -KESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 46.7 bits (111), Expect = 8e-10 Identities = 17/60 (28%), Positives = 28/60 (46%) Query: 15 FESTSAQDAHAGDLNLTLQQIERQHIKRVLHDVGGKVEQASLRLGVPRSTLYQKIKLHGI 74 F S +G + L ++E I L G +A+ LG+ R+TL +KI+ G+ Sbjct: 416 FASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGV 475
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 374 bits (962), Expect = e-129 Identities = 127/358 (35%), Positives = 203/358 (56%), Gaps = 4/358 (1%) Query: 7 RTRILIVDDEDSIRFGMRDFLESRGYGVVDADSCQRARELFQASPPDVAVIDYRLHDGSA 66 IL+ DD+ +IR + L GY V + A D+ V D + D +A Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 67 IDLLRDFRQIDADVPMIVLTAYGSIDLAVQAVKEGAEQFLTKPIEMPALHVILKRLLATR 126 DLL ++ D+P++V++A + A++A ++GA +L KP ++ L I+ R LA Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 127 RLQRQQQVVATRDRRERVNPLSGGSPAIRDLAEQASKVMHTDSPILILGETGTGKSLLAK 186 + + + D + PL G S A++++ +++M TD ++I GE+GTGK L+A+ Sbjct: 123 KRRPSK----LEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVAR 178 Query: 187 WLHHHGMRADEAFVDLNCAGLSPDFLETELFGHEKGAFTGATASKQGMLEIADGGTVFLD 246 LH +G R + FV +N A + D +E+ELFGHEKGAFTGA G E A+GGT+FLD Sbjct: 179 ALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLD 238 Query: 247 EIGDVDPRVQPKLLKVLEEKRFRRLGAVREREVDIRLIAATHHDLASKVKEGTFRSDLYF 306 EIGD+ Q +LL+VL++ + +G D+R++AAT+ DL + +G FR DLY+ Sbjct: 239 EIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYY 298 Query: 307 RISSIPLTMPALRDRKEDIVPLARTLLARSLADPSRTPQLTDDAALALREYAWPGNIR 364 R++ +PL +P LRDR EDI L R + ++ + + +A ++ + WPGN+R Sbjct: 299 RLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVR 356
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 29.3 bits (65), Expect = 0.023 Identities = 13/64 (20%), Positives = 21/64 (32%), Gaps = 8/64 (12%) Query: 143 GVQYKRLRDGTLPLAIGARDDHGTDVYLSAARLLLQGAGGYQLLLNGTVRATRANQTGLL 202 G Q+ + L + + G ++ L Y + GT GL+ Sbjct: 207 GSQFIYKKGDNYSLILNNHEVGGNNLKLVG--------DAYTYGIAGTPYKVNHENNGLI 258 Query: 203 GFGG 206 GFG Sbjct: 259 GFGN 262
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 66.2 bits (161), Expect = 7e-15 Identities = 52/179 (29%), Positives = 82/179 (45%), Gaps = 2/179 (1%) Query: 8 ALITGASSGIGREIARAYAARGMPLILTARRVDRLEALAAELGAQVRV-EILPEDLGDPA 66 A ITGA+ GIG +AR A++G + ++LE + + L A+ R E P D+ D A Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSA 70 Query: 67 APARLVAEIQRQGWTVGTLVNNAGYGMPGRYLQNDWQTHARFLQVMVTAVCELTWRLLPM 126 A + A I+R+ + LVN AG PG + V T V + + Sbjct: 71 AIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSKY 130 Query: 127 IRASGQGRILNVASFAALTPSADGQTLYAAAKSFMLRFSESLALENADCAVKVCALCPG 185 + G I+ V S A P YA++K+ + F++ L LE A+ ++ + PG Sbjct: 131 MMDRRSGSIVTVGSNPAGVPRT-SMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188
>SECGEXPORT#Protein-export SecG membrane protein signature. Length = 110 Score = 95.8 bits (238), Expect = 2e-28 Identities = 41/111 (36%), Positives = 63/111 (56%), Gaps = 9/111 (8%) Query: 5 ILNVVYVLVALAMIALILMQRGAGAAAGSGFGAGASGTVFGSQGASNFLSKSTKWLAVVF 64 L VV+++VA+ ++ LI++Q+G GA G+ FGAGAS T+FGS G+ NF+++ T LA +F Sbjct: 4 ALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFGSSGSGNFMTRMTALLATLF 63 Query: 65 FSISLFMAWYATHGARPTDQNLGVMSQSATPAPAAAGELTQPLPQAPAAGA 115 F ISL + ++ + + APA + Q P APA Sbjct: 64 FIISLVLGNINSNKTNKGSEWENL------SAPA---KTEQTQPAAPAKPT 105
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 77.6 bits (191), Expect = 1e-16 Identities = 47/181 (25%), Positives = 76/181 (41%), Gaps = 29/181 (16%) Query: 408 IMGHVDHGKTSLLDYI-----RRTKIASGEAG-------------GITQHIGAYHVETGR 449 ++ HVD GKT+L + + T++ S + G GIT G + Sbjct: 8 VLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWEN 67 Query: 450 GVISFLDTPGHAAFTSMRARGAKITDIVVLVVAADDGVMPQTKEAVAHAKAAGVPLIVAV 509 ++ +DTPGH F + R + D +L+++A DGV QT+ + G+P I + Sbjct: 68 TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFI 127 Query: 510 NKIDKAGADPLRVKNEL---LAENVVA--------EDFGGDTQFIEVSAKVGTGVDTLLD 558 NKID+ G D V ++ L+ +V + E V G D LL+ Sbjct: 128 NKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGNDDLLE 187 Query: 559 A 559 Sbjct: 188 K 188
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 74.3 bits (182), Expect = 6e-18 Identities = 43/203 (21%), Positives = 86/203 (42%), Gaps = 3/203 (1%) Query: 9 AAALAGRVVLVTGAAGGLGAAAAQACAQAGATVVLLGRKLRPLERVYDALAGQGAAPLLY 68 A + G++ +TGAA G+G A A+ A GA + + LE+V +L + + Sbjct: 3 AKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAF 62 Query: 69 PLDLAGATPDDYAALAQRLQSELGGLSGVLHCAAEFAGLTPAELAAPAEFARSIHVNLTA 128 P D+ + R++ E+G + +L A + E+ + VN T Sbjct: 63 PADV--RDSAAIDEITARIEREMGPID-ILVNVAGVLRPGLIHSLSDEEWEATFSVNSTG 119 Query: 129 RAWLTQACLPLLRQQQDAALVFVVDDPARVGQAYWGAYGAAQHAQRGLIASLHHETAAGS 188 +++ + ++ ++V V +PA V + AY +++ A L E A + Sbjct: 120 VFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYN 179 Query: 189 VRVSGLQPGPMRTALRARAFTHQ 211 +R + + PG T ++ + + Sbjct: 180 IRCNIVSPGSTETDMQWSLWADE 202
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 33.7 bits (77), Expect = 1e-04 Identities = 14/49 (28%), Positives = 28/49 (57%) Query: 5 RARGFTLVELMTTVAVVAIVAAIGYPSFQGVIRSNRAVTANNEVVGLLN 53 + RGFTL+E+M + ++ ++A++ P+ G A +++V L N Sbjct: 6 KQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALEN 54
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 28.3 bits (63), Expect = 0.008 Identities = 8/23 (34%), Positives = 17/23 (73%), Gaps = 2/23 (8%) Query: 8 REASGFTLIEVLIAIIVLAFGLL 30 + GFTL+E+++ I+++ G+L Sbjct: 5 DKQRGFTLLEIMVVIVII--GVL 25
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 29.1 bits (65), Expect = 0.019 Identities = 23/67 (34%), Positives = 31/67 (46%), Gaps = 9/67 (13%) Query: 6 RAAGLSLIEMMIALVIGLVLLLGVIQVFSASRTAFQLSEGASRAQENARF--ALDFLARD 63 R G +L+EMM+ L++ V V+ F ASR S AQ ARF L F+ + Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGMVLLAFPASR-------DDSAAQTLARFEAQLRFVQQR 54 Query: 64 IRMAGHF 70 G F Sbjct: 55 GLQTGQF 61
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 34.5 bits (79), Expect = 4e-05 Identities = 10/39 (25%), Positives = 26/39 (66%) Query: 1 MIELMIVVAVIAILSAIAYPSYAEYVRKSRRAQAKADLV 39 ++E+M+V+ +I +L+++ P+ K+ + +A +D+V Sbjct: 12 LLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIV 50
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 34.1 bits (78), Expect = 1e-04 Identities = 10/38 (26%), Positives = 24/38 (63%) Query: 8 PAKGYTATELLIVMAVLGLLAAIALPSFSSLIERQRLQ 45 +G+T E+++V+ ++G+LA++ +P+ E+ Q Sbjct: 6 KQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQ 43
>PF04335#VirB8 type IV secretion protein Length = 227 Score = 219 bits (560), Expect = 6e-73 Identities = 53/230 (23%), Positives = 104/230 (45%), Gaps = 12/230 (5%) Query: 14 QVGAAVQKAVNYEVSIADLARRSERRAWLVATVSMLITVITAGGYYYMLPLKEKVPYLVM 73 ++ A ++A ++E A RS++ AW+VA V+ + + PLK PY++ Sbjct: 9 ELKAYFEEAASWERDKLAAAERSKKLAWVVAGVAGALATAGVVAVAALTPLKTVEPYVIT 68 Query: 74 ADAYSGTSTIAKLEANYGGRTISTSEALARSNIARFILARESFDVSTIGDRDWNTVAAMA 133 D +G ++I +G TI+ EA+ + +A ++ RE + + + ++ V M+ Sbjct: 69 VDRNTGEASI--AAKLHGDATITYDEAVRKYFLATYVRYREGWIAAAR-EEYFDAVMVMS 125 Query: 134 ATNVLAEYRTLHAGNNPLRPFNTYGRSRAIRINILSITLVGGKGKAYTGATVRFQRNVYD 193 A + + +NP P N + + I ++ +GG A V F + Sbjct: 126 ARPEQDRWSRFYKTDNPQSPQNILANRTDVFVEIKRVSFLGGN-----VAQVYFTKESVT 180 Query: 194 KTSTVTTLLDNKIATMGFAYQDNLQMSDSLRVENPLGFRVTDYRVDSDYS 243 +++ T + +AT+ + D + R +NPLG++V YR D + Sbjct: 181 GSNSTKT---DAVATIKYKV-DGTPSKEVDRFKNPLGYQVESYRADVEVP 226
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 36.3 bits (83), Expect = 8e-05 Identities = 27/89 (30%), Positives = 42/89 (47%), Gaps = 10/89 (11%) Query: 44 TGLGITTQIELSPNEKILDYSTGFTGGWELTRRENVFYLKPKNVDVD-------TNMMIR 96 T L T I+L +E I +TGF GW + N +++PK+V + N + Sbjct: 59 TSLDNVTVIQLEKDETISYITTGFNKGWSIVPNSNHIFIQPKSVKSNLMFEKEAVNFALM 118 Query: 97 TATHSYILELK---VVATDWQRLEQAKQA 122 T + L+ K V A D + LE+ K+A Sbjct: 119 TRDYQEFLKTKKLIVDAPDPKELEEQKKA 147 Score = 29.8 bits (66), Expect = 0.011 Identities = 11/27 (40%), Positives = 17/27 (62%) Query: 165 YDYDYATRTKKSWLVPSRVYDDGKFTY 191 Y+Y A + ++PS ++DDG FTY Sbjct: 401 YNYYQAPEKRSKHIMPSEIFDDGTFTY 427
>MYCMG045#Hypothetical mycoplasma lipoprotein (MG045) signature. Length = 483 Score = 33.9 bits (77), Expect = 0.001 Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 19/105 (18%) Query: 119 LPSKHTKTLEQYTSDGFFDEVLEQAADVSEQDRELLELRRSKQYSEFFKKSVLYKKNVVV 178 L K + Q T D +E+L A Q+ L+ + R ++ SE +++V + Sbjct: 119 LFIDSIKEISQQTKDSKNNELLHWAVPYFLQN--LVFVYRGEKISELEQENVSW------ 170 Query: 179 AGATGSGKTTFMKALVNHIP--NEERLVTIEDARELFISQPNSVH 221 T +KA+V H N+ RLV I+DAR +F S N V+ Sbjct: 171 --------TDVIKAIVKHKDRFNDNRLVFIDDARTIF-SLANIVN 206
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 117 bits (295), Expect = 3e-38 Identities = 35/89 (39%), Positives = 55/89 (61%) Query: 4 TKAEMAERLFDEVGLNKREAKEFVDAFFDVLRDALEQGRQVKLSGFGNFDLRRKNQRPGR 63 K ++ ++ + L K+++ VDA F + L +G +V+L GFGNF++R + R GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 64 NPKTGEEIPISARTVVTFRPGQKLKERVE 92 NP+TGEEI I A V F+ G+ LK+ V+ Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAVK 91
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 40.3 bits (94), Expect = 1e-05 Identities = 19/111 (17%), Positives = 30/111 (27%) Query: 99 AAVPSAPTPAPAAAPSALQALPDPVAPSAPATATPVVVVPTPQPLPQAAPAAPLQAPTPA 158 A + P P P P A V+ P P+P P+ P ++ P Sbjct: 58 ADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRD 117 Query: 159 VTPAAQVATPQVAVPPVVPAPAAPAVPAATPPAAYAPAPAAPVVTTPVAAP 209 V P ++ A A + P + + P Sbjct: 118 VKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQYP 168 Score = 36.1 bits (83), Expect = 2e-04 Identities = 23/124 (18%), Positives = 35/124 (28%), Gaps = 6/124 (4%) Query: 97 SIAAVPSAPTP------APAAAPSALQALPDPVAPSAPATATPVVVVPTPQPLPQAAPAA 150 + +P+ P APA P P P + P + Sbjct: 39 QVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPK 98 Query: 151 PLQAPTPAVTPAAQVATPQVAVPPVVPAPAAPAVPAATPPAAYAPAPAAPVVTTPVAAPT 210 P P P + V PA A P ++ A A + VT+ + P Sbjct: 99 PKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGPR 158 Query: 211 HLVQ 214 L + Sbjct: 159 ALSR 162 Score = 34.6 bits (79), Expect = 6e-04 Identities = 25/144 (17%), Positives = 38/144 (26%), Gaps = 5/144 (3%) Query: 21 YSLEELAAAFPTAPSAATPAAPPAPTQTPPASAPTTPVAPVAAPSTPAAETPTPTAPAAP 80 Y+ P + AP P A P PV P P P A Sbjct: 34 YTSVHQVIELPAPAQPIS-VTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPV 92 Query: 81 AEQLAQDIAARTGQAQSIAAVPSAPTPAPAAAPSALQALPDPVAPSAPATATPVVVVPTP 140 + + + P + P+ + + AP+ P ++T P Sbjct: 93 VIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPA---SPFENTAPARPTSSTATAATSKP 149 Query: 141 QPLPQAAPAAPLQAPTPAVTPAAQ 164 A+ L P AQ Sbjct: 150 VTSV-ASGPRALSRNQPQYPARAQ 172 Score = 31.1 bits (70), Expect = 0.009 Identities = 17/123 (13%), Positives = 26/123 (21%), Gaps = 1/123 (0%) Query: 120 PDPVAPSAPATATPVVVVPTPQPLPQAAPAAPLQAPTPAVTPAA-QVATPQVAVPPVVPA 178 + AP+ P + T V P P P+ P P P V + P Sbjct: 41 IELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPK 100 Query: 179 PAAPAVPAATPPAAYAPAPAAPVVTTPVAAPTHLVQDSGIDTHDSLPAAPAGKPGWRERL 238 P P T + + + L Sbjct: 101 PKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRAL 160 Query: 239 RNS 241 + Sbjct: 161 SRN 163
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 284 bits (729), Expect = 4e-97 Identities = 74/207 (35%), Positives = 113/207 (54%), Gaps = 7/207 (3%) Query: 209 PLVELHAPGS---DRLVVLLSGDGGWREMDKGIAARLQQQGVSVVGFNSLRYFWGSRTPQ 265 P +++A S LV+ LSGDGGW +DK + LQQQG VVG++SL+Y+W + P+ Sbjct: 38 PSTQVNAASSHTKPPLVIFLSGDGGWATLDKAVGGILQQQGWPVVGWSSLKYYWKQKDPK 97 Query: 266 QVGVDLDRIIATYQQRWHAHHVALVGYSFGADVLPFAFPELPAARRDAVQFVGLLGLAHQ 325 V D II YQ + V L+GYSFGA+V+PF E+PA R V LL + Sbjct: 98 DVTQDTLAIIDKYQAEFGTQKVILIGYSFGAEVIPFVLNEMPARYRKNVLGAVLLSPSQS 157 Query: 326 ADFKVRVGGWLGWHNEAER-PIAPALQALDAHRLQCIYGEQEKDT--LCPELRARGVEVI 382 +DF++ V + N++ R P + + C+YG+++ LCPE++ V V+ Sbjct: 158 SDFEIHVSEMVTSDNQSARYLTLPEVNKQTTVPMLCLYGKEDDAPLHLCPEVKQPNVTVM 217 Query: 383 ARPGGHHFDRDPGALADILLQGWQRAA 409 GGH FD D + + ++GW + + Sbjct: 218 ELSGGHSFDDDYDKVVKL-IKGWLKPS 243
>FLGFLIJ#Flagellar FliJ protein signature. Length = 147 Score = 28.2 bits (62), Expect = 0.037 Identities = 22/78 (28%), Positives = 34/78 (43%), Gaps = 7/78 (8%) Query: 250 QQLAQQYSPMID---KYRDDVASMRLGATLGTRSMQ----AMTLADGIDQLRGTLAPGAG 302 QQ +Q +ID +YR+++ S R + TL I Q R L Sbjct: 33 QQAEEQLKMLIDYQNEYRNNLNSDMSAGITSNRWINYQQFIQTLEKAITQHRQQLNQWTQ 92 Query: 303 RADMAAARWEEVQQRMQS 320 + D+A W E +QR+Q+ Sbjct: 93 KVDIALNSWREKKQRLQA 110
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.4 bits (68), Expect = 0.029 Identities = 18/168 (10%), Positives = 48/168 (28%), Gaps = 13/168 (7%) Query: 368 AGERPAAYAGTVLVEAAQGAETTG-------ESAPDLLDSAMQDTADDRANPPLESKPSL 420 E + TV ETT E+ ++ + + + E++ + Sbjct: 1040 VAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTE 1099 Query: 421 STQPVAKNAPDMMDELL------AMIGAPDPPKADDQGSSSSQPMPEAPGKPHQVSESVP 474 + + + + + PK + + Q P P + Sbjct: 1100 TKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQ 1159 Query: 475 AKKNPMSTSTQPSRDESNGTSTQMSADHFVTWLQQAIASRRLVINDAK 522 ++ N + + QP+++ S+ ++ V + + Sbjct: 1160 SQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATT 1207
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 26.0 bits (57), Expect = 0.045 Identities = 8/25 (32%), Positives = 11/25 (44%), Gaps = 3/25 (12%) Query: 20 GWRAYARGERRLSSWLASKGVPVVG 44 GW + + L +G PVVG Sbjct: 62 GWATLDKA---VGGILQQQGWPVVG 83
>PF02370#M protein repeat Length = 168 Score = 31.2 bits (70), Expect = 0.006 Identities = 13/64 (20%), Positives = 25/64 (39%), Gaps = 4/64 (6%) Query: 84 KSQREENQRLRQRENSIDQRINSAL----ETERSNLRRDQQQAASERQQTEGLLADLQQR 139 ++ ENQ LR+RE +I E + RR++ + + + + QQ Sbjct: 51 RALMGENQDLRKREGQYQDKIEELEKERKEKQERPERREKFERQHQDKHYQEQQKKHQQE 110 Query: 140 LDSI 143 + Sbjct: 111 QQQL 114
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 27.5 bits (60), Expect = 0.048 Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 4/41 (9%) Query: 124 ATPARASRPAKPAPVQASADPLVDTTPFGVDAQPLDTSAAP 164 ++A + P+PV A+A PL+ QPL T AAP Sbjct: 193 EAQSKAEVISTPSPVTAAASPLITPH----QTQPLPTVAAP 229
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 31.4 bits (71), Expect = 0.004 Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 12/46 (26%) Query: 168 SQSELARRLVADGYPVQQSHISRMAD---AVR---------YLLPA 201 +Q EL L DGY V Q+ +SR V+ Y LPA Sbjct: 21 TQDELVDILKKDGYNVTQATVSRDIKELHLVKVPTNNGSYKYSLPA 66
>BONTOXILYSIN#Bontoxilysin signature. Length = 1196 Score = 32.6 bits (74), Expect = 0.004 Identities = 16/74 (21%), Positives = 36/74 (48%), Gaps = 1/74 (1%) Query: 303 VYDCFVYEVIYKKKTYVLFSGEWYC-IESKFFDAVEKDYQALLGVSFHLKTKAKNEQELI 361 +Y+ + ++Y KK Y F +W+ S++F+ + Q++L +K +N+ + Sbjct: 650 LYEIYSKNIVYFKKIYFSFLDQWWTEYYSQYFELICMAKQSILAQESLVKQIVQNKFTDL 709 Query: 362 SELDKNSNLLNLDK 375 S+ + L L + Sbjct: 710 SKASIPPDTLKLIR 723
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 50.1 bits (119), Expect = 3e-08 Identities = 43/273 (15%), Positives = 81/273 (29%), Gaps = 21/273 (7%) Query: 156 DAAPATAASGAQQAAASAVAASSAAASPASTSSTVAEPAEPAADVPDVAPEPAVAAAAEP 215 D T + Q S + + A PA P+ VA + Sbjct: 993 DTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTV- 1051 Query: 216 STPDIPQVRVQVPQVTLESPLQVTETPVPTTDFVVPPPPTITVAPRAIEPAAPQVRQREI 275 + Q T +V + + E A +E Sbjct: 1052 ------EKNEQDATETTAQNREVAKEAKSNVKA----------NTQTNEVAQSGSETKET 1095 Query: 276 QT-VTERPQVRELQQPTAAVAVRAAAAPTVREREIVVPEQARVTAPTVR-AREVVPTVRM 333 QT T+ E ++ + P V + EQ+ P ARE PTV + Sbjct: 1096 QTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNI 1155 Query: 334 PELAVRAAELPNVPDPAPQPTPAQTPPAQPAVVQTPSAAAVSISPAAPAPSSA-PSPANQ 392 E + + PA + T + + +V +P P++ P+ ++ Sbjct: 1156 KEPQSQTNTTADTEQPA-KETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSE 1214 Query: 393 TNQQTAAQSAKPASAAAASSKPAASSGAGPKPV 425 ++ + + + + + +PA +S V Sbjct: 1215 SSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTV 1247 Score = 37.0 bits (85), Expect = 3e-04 Identities = 19/141 (13%), Positives = 39/141 (27%), Gaps = 9/141 (6%) Query: 144 AEQGGGEGEPAADAAPATAASGAQQAAASAV---AASSAAASPASTSSTVAEPAEPAADV 200 E+ + + +P S Q A + P S ++T A+ +PA + Sbjct: 1116 TEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKET 1175 Query: 201 PDVAPEPAVAAAAEPSTPDIPQVRVQVPQVTLESPLQVTETPVPTTDFVVPPPPTITVAP 260 +P + + + + P+ T + Q T + +V Sbjct: 1176 SSNVEQPVTESTTVNTGNSVV----ENPENTTPATTQPTVN--SESSNKPKNRHRRSVRS 1229 Query: 261 RAIEPAAPQVRQREIQTVTER 281 + TV Sbjct: 1230 VPHNVEPATTSSNDRSTVALC 1250 Score = 32.7 bits (74), Expect = 0.005 Identities = 19/98 (19%), Positives = 36/98 (36%), Gaps = 2/98 (2%) Query: 339 RAAELPNVPDPAPQPTPAQTPPAQPAVVQTPSAAAVSISPAAPAPSSAPSPANQTNQQTA 398 + D TP P+V + ++ AP P AP+ ++T + A Sbjct: 984 EVEKRNQTVDTTNITTPNNIQADVPSVPS--NNEEIARVDEAPVPPPAPATPSETTETVA 1041 Query: 399 AQSAKPASAAAASSKPAASSGAGPKPVDRSGGWDVAAN 436 S + + + + A + A + V + +V AN Sbjct: 1042 ENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKAN 1079
>AEROLYSIN#Aerolysin signature. Length = 493 Score = 26.9 bits (59), Expect = 0.020 Identities = 14/66 (21%), Positives = 24/66 (36%), Gaps = 3/66 (4%) Query: 5 TYDHVDLTGPWAGFGFQGYRFFTPEGREVRPEEMRWWSLTCTIAREWALMMAEERERVWH 64 ++H + GP+ + + P E++WW TI + M RV Sbjct: 361 NWNHTFVIGPYKD---KASSIRYQWDKRYIPGEVKWWDWNWTIQQNGLSTMQNNLARVLR 417 Query: 65 PRPAEV 70 P A + Sbjct: 418 PVRAGI 423
>PF06580#Sensor histidine kinase Length = 349 Score = 32.1 bits (73), Expect = 5e-04 Identities = 12/54 (22%), Positives = 24/54 (44%), Gaps = 9/54 (16%) Query: 2 FVLLQALGWALF----LAIAYVARPSEDSVPELLQLAGVVAMSICGLLGSLALR 51 + Q +GW ++ A + P+L + +A+S+ GL+ + A R Sbjct: 12 YWYCQGIGWGVYTLTGFGFASLYGS-----PKLHSMIFNIAISLMGLVLTHAYR 60
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 111 bits (278), Expect = 1e-28 Identities = 62/318 (19%), Positives = 111/318 (34%), Gaps = 39/318 (12%) Query: 106 NADLAQQAGARGQGVKIGVMDDNLVQTYAPVAGKVDAFTDYTAVPGAAESTSNRLRGHGS 165 A G+GVK+ V+D + + ++ ++T GHG+ Sbjct: 30 QAPAVWNQTR-GRGVKVAVLDTGCDADHPDLKARIIGGRNFTDDDEGDPEIFKDYNGHGT 88 Query: 166 VVSALVLGSAQDGFAGGVAPDADLIYGRICAENSCGTQQARRAAVDMAAA-GVRIANLSI 224 V+ + + + GVAP+ADL+ ++ + G + A V I ++S+ Sbjct: 89 HVAGTIAATENENGVVGVAPEADLLIIKVLNKQGSGQYDWIIQGIYYAIEQKVDIISMSL 148 Query: 225 GASYADAASSANAALAWRFALTPLVQADALIVASTGNDGAAEAS-----YPAAAPVQEAS 279 G A V + L++ + GN+G + YP Sbjct: 149 GGPEDVPELHEAVKKA--------VASQILVMCAAGNEGDGDDRTDELGYPGCYN----- 195 Query: 280 LRNNWLAVGAVEIDSAGNPAGLSSYSNHCGSAAQWCLVAPGMYAAPALAGTELQGQIAGT 339 ++VGA+ D S +SN LVAPG + G + +GT Sbjct: 196 ---EVISVGAINFDR-----HASEFSNSNNE---VDLVAPGEDILSTVPGGKYA-TFSGT 243 Query: 340 SFSTAAVSGVAAQVLGVYPW-----MSASNLQQTLLTTATDLGDPGVDALYGWGMVNAAK 394 S +T V+G A + + ++ L L+ LG + G G++ Sbjct: 244 SMATPHVAGALALIKQLANASFERDLTEPELYAQLIKRTIPLG--NSPKMEGNGLLYLTA 301 Query: 395 AIKGPGQFASNWAANVTS 412 + F + A + S Sbjct: 302 VEELSRIFDTQRVAGILS 319
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 35.4 bits (81), Expect = 0.006 Identities = 46/213 (21%), Positives = 70/213 (32%), Gaps = 38/213 (17%) Query: 2096 FGGSLSDAGNLE-----KVGTGVFQLTGTSSIGGTTLVSAGTLDVDGTLASAGGLTVANG 2150 + GNL K F LTG +++ G V GTL G + Sbjct: 657 GEEEGKNNGNLNVTFKGKSEQNRFLLTGGTNLNGDLTVEKGTL-------FLSGRPTPHA 709 Query: 2151 GALSGSGVVDAAVTVADGGRVVVSS---GALLTTGTLSLAPNATIDAFLGIPSQTGVLAV 2207 ++G A+ VVV T+++ NA + G V + Sbjct: 710 RDIAGISSTKKDPHFAENNEVVVEDDWINRNFKATTMNVTGNA--SLYSGRN----VANI 763 Query: 2208 NGDLTLDGTLNITDIGGFGNGVYRLIDYTG-------GLSDNGLAFGTIPGSVDPTQLAL 2260 ++T + G+ V DYTG LSD L S +PT L Sbjct: 764 TSNITASNKAQVHIGYKTGDTVCVRSDYTGYVTCTTDKLSDKALN------SFNPTNLRG 817 Query: 2261 QTALAQQVNVVVSAPGSNVQFWDGAQTVGNAQI 2293 L + N V+ + Q+ GN+Q+ Sbjct: 818 NVNLTESANFVL----GKANLFGTIQSRGNSQV 846
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 89.1 bits (221), Expect = 3e-22 Identities = 58/260 (22%), Positives = 101/260 (38%), Gaps = 29/260 (11%) Query: 1 MRILITGNMGYIGPVVARHLRQQYPDAWLVGLD--RGWFAHCLSDPRQLPEVVLDQQWF- 57 M+ L+TG G+IG V++ L + +VG+D ++ L R E++ + Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQ--VVGIDNLNDYYDVSLKQARL--ELLAQPGFQF 56 Query: 58 --GDVRDLTA----QQLSGFDGVVHLAAISNDAMGKRFE----QVTDAINCRASVAVAQA 107 D+ D F+ V + R+ N + + + Sbjct: 57 HKIDLADREGMTDLFASGHFERVFISPH----RLAVRYSLENPHAYADSNLTGFLNILEG 112 Query: 108 AAQAGVKHFVFASSCSVYGAAADGTPRSESSAVA-PLTAYAHSKIDTERALAQLET---D 163 ++H ++ASS SVYG P S +V P++ YA +K E +A + Sbjct: 113 CRHNKIQHLLYASSSSVYGLNRK-MPFSTDDSVDHPVSLYAATKKANEL-MAHTYSHLYG 170 Query: 164 MVITCLRFATACGASPRLRLDLVLNDFVASAVANGTVEVLSDGSPWRPLIHVRDMARAID 223 + T LRF T G P R D+ L F + + +++V + G R ++ D+A AI Sbjct: 171 LPATGLRFFTVYG--PWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAII 228 Query: 224 WALGRTPLAGGRFLAVNAGA 243 P A ++ Sbjct: 229 RLQDVIPHADTQWTVETGTP 248
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 34.1 bits (78), Expect = 0.001 Identities = 29/130 (22%), Positives = 57/130 (43%), Gaps = 10/130 (7%) Query: 61 AVLRLVLGMLADRIGAKRAGVVA-QLAVIASLFGAWQLGVHSMGQVLLLG-VLLGIAGAS 118 ++ V G L+D++G KR + + S+ G HS +L++ + G A+ Sbjct: 63 SIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVG---HSFFSLLIMARFIQGAGAAA 119 Query: 119 F-AVALPLASRWYPPEHQCTAMG-IAGAGNSGTVLAALFAPMLALAFGYQNVFGLACIPL 176 F A+ + + +R+ P E++ A G I G + M+A + + IP+ Sbjct: 120 FPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLL---LIPM 176 Query: 177 VLTLLVFVLI 186 + + V L+ Sbjct: 177 ITIITVPFLM 186
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 59.1 bits (143), Expect = 1e-12 Identities = 35/142 (24%), Positives = 57/142 (40%), Gaps = 8/142 (5%) Query: 2 RVLLVNDTEKPIGELRQALSRAGYTVLDDVASVSALLHAVQSQQPDVVVIDVDSPSRDTL 61 +L+ +D L QALSRAGY V ++ + L + + D+VV DV P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 EQLSMLHAHAPR-PVVMFSGDGDDALIHAAVGAGVTAYVVDGLAPARLAPIVQVALARFA 120 + L + P PV++ S A G Y+ L I+ ALA Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE-- 121 Query: 121 HENSMRKRLDEVQQALQDRKQI 142 ++R +++ QD + Sbjct: 122 ----PKRRPSKLEDDSQDGMPL 139
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 61.2 bits (148), Expect = 1e-15 Identities = 28/84 (33%), Positives = 48/84 (57%) Query: 40 AGAQGTPATQAPSFSETLRGAIGGVNEAQQKSGALAKAFEMGDPSADLARVMVASQQSQV 99 A AQ + SF+ L A+ +++ Q + A+ F +G+P L VM Q++ V Sbjct: 20 ARAQESLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTLGEPGVALNDVMTDMQKASV 79 Query: 100 AFRATVEVRNRLVQAYQDVMNMPL 123 + + ++VRN+LV AYQ+VM+M + Sbjct: 80 SMQMGIQVRNKLVAAYQEVMSMQV 103
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 347 bits (891), Expect = e-115 Identities = 184/576 (31%), Positives = 295/576 (51%), Gaps = 48/576 (8%) Query: 16 KAGQWFDRIRSMQITRKLTMMAMIALAVAAGLAVFFWSQKPGYQALYTGLDDKGNAEAAD 75 K +W +R+R+ ++ ++ + AVA +A+ W++ P Y+ L++ L D+ Sbjct: 11 KPLEWLNRLRANP---RIPLIVAGSAAVAIVVAMVLWAKTPDYRTLFSNLSDQDGGAIVA 67 Query: 76 LLRTAQIPFKIDQSTGAISVPQDRLYDARLKLAGSGLTGQQTGGGFELMEKDPGFGVSQF 135 L IP++ +GAI VP D++++ RL+LA GL + GFEL++++ FG+SQF Sbjct: 68 QLTQMNIPYRFANGSGAIEVPADKVHELRLRLAQQGLP-KGGAVGFELLDQEK-FGISQF 125 Query: 136 VENARYQHALETELSRTIGTLRPVREARVHLAIPKPSAFTRQRDVASASVVLELRGGQGL 195 E YQ ALE EL+RTI TL PV+ ARVHLA+PKPS F R++ SASV + L G+ L Sbjct: 126 SEQVNYQRALEGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLEPGRAL 185 Query: 196 ERNQVDAIVNLVASSIPDMTPERVTVVDQSGRMLSIADPNSDAAQHAAQFEQVRRQESSY 255 + Q+ A+V+LV+S++ + P VT+VDQSG +L+ ++ + AQ + ES Sbjct: 186 DEGQISAVVHLVSSAVAGLPPGNVTLVDQSGHLLTQSNTSGRDLN-DAQLKFANDVESRI 244 Query: 256 NQRIRELLEPMTGAGRVNPEVSVDMDFSVVEEARELYN----GEPAKLRSEQVSDSS-TS 310 +RI +L P+ G G V+ +V+ +DF+ E+ E Y+ A LRS Q++ S Sbjct: 245 QRRIEAILSPIVGNGNVHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQVG 304 Query: 311 ATGPQGPPGATSNSPGQPPAPAATAGAPGAPAAGQAATPAAPTES----------SKSAT 360 A P G PGA SN P P A P TP T + ++ T Sbjct: 305 AGYPGGVPGALSNQP--APPNEAPIATPPTNQQNAQNTPQTSTSTNSNSAGPRSTQRNET 362 Query: 361 RNYELDRTLQHTRQPAGRIKRVSVAVLLDNVPRPGAKGKIVEQPLTAAELTRIEGLVKQA 420 NYE+DRT++HT+ G I+R+SVAV+++ K PLTA ++ +IE L ++A Sbjct: 363 SNYEVDRTIRHTKMNVGDIERLSVAVVVNYKTLADGKP----LPLTADQMKQIEDLTREA 418 Query: 421 VGFDAARGDTVSVMNAPFVREAVAGEEGPKWWEDPRVQNGLRLLVGAVVVLALLF----G 476 +GF RGDT++V+N+PF G E P W + + L ++VL + + Sbjct: 419 MGFSDKRGDTLNVVNSPFSAVDNTGGELPFWQQQSFIDQLLAAG-RWLLVLVVAWILWRK 477 Query: 477 VVRPTLRQLTGTAAVKEKHKKGGNDGTPQSADVRMVDEDDDLMPRLEEDTAQIGQDKKLP 536 VRP L + A ++ + + + L +E Q +++L Sbjct: 478 AVRPQLTRRVEEAKAAQEQAQVRQET--------EEAVEVRLSK--DEQLQQRRANQRLG 527 Query: 537 IALPDAYEERVRLAREAVKADSKRVAQVVKGWVASE 572 E + RE D + VA V++ W++++ Sbjct: 528 ------AEVMSQRIREMSDNDPRVVALVIRQWMSND 557
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 307 bits (789), Expect = e-106 Identities = 105/329 (31%), Positives = 199/329 (60%) Query: 1 MSGVQRAAVLLLSLGETDAAEVLKHMDPKEVQKIGIAMATMSGISRDQVEKVMDDFNGEL 60 ++G Q+AA+LL+S+G +++V K++ +E++ + +A + I+ + + V+ +F + Sbjct: 15 LTGKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKLETITSELKDNVLLEFKELM 74 Query: 61 AGKTSLGVGADDYIRNVLIQALGADKAGGLIDRILLGRNTTGLDTLKWMDPRAVADLVRN 120 + + G DY R +L ++LG KA +I+ + + + ++ DP + + ++ Sbjct: 75 MAQEFIQKGGIDYARELLEKSLGTQKAVDIINNLGSALQSRPFEFVRRADPANILNFIQQ 134 Query: 121 EHPQIIAIVMAHLDSDQAAEALKLLPERTRADVLLRIATLDGIPPNALSELNDIMERQFA 180 EHPQ IA+++++LD +A+ L LP + +V RIA +D P + E+ ++E++ A Sbjct: 135 EHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVVREVERVLEKKLA 194 Query: 181 GNQNLKSSNVGGIKVAANILNFLDTGPEQGVLGEIGKIDADLASKIQDLMFVFDNLVDLD 240 + ++ GG+ I+N D E+ ++ + + D +LA +I+ MFVF+++V LD Sbjct: 195 SLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPELAEEIKKKMFVFEDIVLLD 254 Query: 241 DRGLQTLLREVSGERLGLALRGADVKVREKITRNMSQRAAEILLEDMEARGPVRLADVEA 300 DR +Q +LRE+ G+ L AL+ D+ V+EKI +NMS+RAA +L EDME GP R DVE Sbjct: 255 DRSIQRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRAASMLKEDMEFLGPTRRKDVEE 314 Query: 301 AQKEILTIVRRLADEGAISLGGAGAEAMV 329 +Q++I++++R+L ++G I + G E ++ Sbjct: 315 SQQKIVSLIRKLEEQGEIVISRGGEEDVL 343
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 44.4 bits (104), Expect = 7e-08 Identities = 36/159 (22%), Positives = 76/159 (47%), Gaps = 7/159 (4%) Query: 51 QEGFARGHAEGFAQGQSEVRRLTAQIDGILDNFTRPLARLENEVVGALGELTVRIAGSLV 110 QEG A+G +G A+ +S+ + A++ ++ F L L++ + L ++ + A ++ Sbjct: 73 QEGLAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRLMQMALEAARQVI 132 Query: 111 GRAYQAEPQLLADLVQEAIDAVGSAGREVEVRLHPDDITALLPHLATSSTT---RVAPDL 167 G+ + L +Q+ + + ++R+HPDD+ + L + + R+ D Sbjct: 133 GQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGATLSLHGWRLRGDP 192 Query: 168 TLSRGDLRVHAESVRVDGTLDARLRAALETVMRKSGAGL 206 TL G +V A+ +G LDA + + + R + G+ Sbjct: 193 TLHPGGCKVSAD----EGDLDASVATRWQELCRLAAPGV 227
>FLGFLIJ#Flagellar FliJ protein signature. Length = 147 Score = 27.5 bits (60), Expect = 0.017 Identities = 34/140 (24%), Positives = 57/140 (40%), Gaps = 4/140 (2%) Query: 1 MMQSKRIDPLLRRAQEQEDKVARDLAERQRALDTHQSRLEELRRYAEEYASSQMSGTSAV 60 M + + L A+++ + AR L E +R + +L+ L Y EY ++ S SA Sbjct: 1 MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAG 60 Query: 61 ALSNR----RAFLDRLDSAVLQQAQTVESNRAKVEAERTRLLLASREKQVLEQLAASYRA 116 SNR + F+ L+ A+ Q Q + KV+ + Q + L Sbjct: 61 ITSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQST 120 Query: 117 QENKVIERRDQREMDDLGAR 136 R DQ++MD+ R Sbjct: 121 AALLAENRLDQKKMDEFAQR 140
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 46.4 bits (109), Expect = 1e-07 Identities = 55/241 (22%), Positives = 96/241 (39%), Gaps = 17/241 (7%) Query: 178 ASMSAATTATTATPTLPTDAAAPATTATAATALPSLGALAPAAATAKPAAATALSGEPQA 237 AS+SA P AP+T + TA+P A +P Sbjct: 129 ASLSALFAMLPGFDNTPKVTDAPSTVLPTEKPTLFTKLTSEQLTTAQPDDAPGTPAQP-- 186 Query: 238 AALMSLATAALDSPADDLKTDAPDAPAFVLPTTTASALNRLQDAPAVFSASPTPTPEMGS 297 ++ A S A+ + T +P A T P A+P + +GS Sbjct: 187 ---LTPLVAEAQSKAEVISTPSPVTAAASPLITPHQT------QPLPTVAAPVLSAPLGS 237 Query: 298 DTFDDAIGARLSWLADQKIGHAHIKVTPNEMGPVEVRLHLEGDKVNASFTAANADVRQAL 357 + ++ +S Q A +++ P ++G V++ L ++ ++ + + VR AL Sbjct: 238 HEWQQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMVSPHQHVRAAL 297 Query: 358 EQSLPRLRDMLGQQGFQLGQADVS------QQQQNPSGNRNGAGTDGNGLSLEDSPPVGI 411 E +LP LR L + G QLGQ+++S QQQ ++ + L+ ED + + Sbjct: 298 EAALPVLRTQLAESGIQLGQSNISGESFSGQQQAASQQQQSQRTANHEPLAGEDDDTLPV 357 Query: 412 P 412 P Sbjct: 358 P 358
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 115 bits (289), Expect = 1e-36 Identities = 54/103 (52%), Positives = 78/103 (75%), Gaps = 1/103 (0%) Query: 9 AAPATFESLHAERDQDATDLNLDVILDVPVTLSLEVGRARIPIRNLLQLNQGSVVELERG 68 AA A F+ L D ++D+I+D+PV L++E+GR R+ I+ LL+L QGSVV L+ Sbjct: 34 AADAVFQQL-GGGDVSGAMQDIDLIMDIPVKLTVELGRTRMTIKELLRLTQGSVVALDGL 92 Query: 69 AGEPLDVYVNGTLIAHGEVVVINDRFGIRLTDVVSPSERIRRL 111 AGEPLD+ +NG LIA GEVVV+ D++G+R+TD+++PSER+RRL Sbjct: 93 AGEPLDILINGYLIAQGEVVVVADKYGVRITDIITPSERMRRL 135
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 241 bits (616), Expect = 4e-82 Identities = 123/229 (53%), Positives = 162/229 (70%), Gaps = 1/229 (0%) Query: 49 APATGNQIPTLPNVSVGRIGDQPVSLPLQTLLLMTAITLLPSMLLVLTAFTRITIVLGLL 108 P Q+P + + + G Q SLP+QTL+ +T++T +P++LL++T+FTRI IV GLL Sbjct: 16 TPLAFAQLPGITSQPL-PGGGQSWSLPVQTLVFITSLTFIPAILLMMTSFTRIIIVFGLL 74 Query: 109 RQALGTGQTPSNQVLLGLAMFLTALVMMPVWQKMWGAGLQPYLNNQIDFSTAWTLTTQPL 168 R ALGT P NQVLLGLA+FLT +M PV K++ QP+ +I A QPL Sbjct: 75 RNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEKISMQEALEKGAQPL 134 Query: 169 RAFMLAQIRETDLMTFAGMAGDGKYAGPDAVPFPVLVASFVTSELKTAFEIGFLIFIPFV 228 R FML Q RE DL FA +A G GP+AVP +L+ ++VTSELKTAF+IGF IFIPF+ Sbjct: 135 REFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELKTAFQIGFTIFIPFL 194 Query: 229 IIDLVVASVLMSMGMMMLSPMLISAPFKILLFILVDGWVLVVGTLAASF 277 IIDLV+ASVLM++GMMM+ P I+ PFK++LF+LVDGW L+VG+LA SF Sbjct: 195 IIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLAQSF 243
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 45.9 bits (109), Expect = 2e-10 Identities = 17/69 (24%), Positives = 33/69 (47%) Query: 13 GLVTVLWIAGPMLLAVLVVGVVIGVVQAATQLNEPTIGFVAKAVALTATLFATGSMLLGH 72 L VL ++G + ++G+++G+ Q TQL E T+ F K + + LF Sbjct: 11 ALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLFLLSGWYGEV 70 Query: 73 LVEFTIELF 81 L+ + ++ Sbjct: 71 LLSYGRQVI 79
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 121 bits (305), Expect = 2e-35 Identities = 80/239 (33%), Positives = 130/239 (54%), Gaps = 2/239 (0%) Query: 23 WTMLRTGALLTAMPLIGTRAVPGRVRVMLTGTLAMALAPILPPVPEWDGFNATAVLSIAR 82 W +LR AL++ P++ R+VP RV++ L + A+AP LP F+ A+ + Sbjct: 18 WPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPANDVPV-FSFFALWLAVQ 76 Query: 83 ELAVGASMGFMLRLIFEAGALAGELVSQATGLSFAQMSDPLRGVTSGVIAQWFYIGFGLL 142 ++ +G ++GF ++ F A AGE++ GLSFA DP + V+A+ + LL Sbjct: 77 QILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHLNMPVLARIMDMLALLL 136 Query: 143 FFAANGHLAVIALLVDSYKALPIGTAVPDAAAFAEVAPTLLLQVLRGGLTLALPMMVAML 202 F NGHL +I+LLVD++ LPIG ++ AF + + GL LALP++ +L Sbjct: 137 FLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALT-KAGSLIFLNGLMLALPLITLLL 195 Query: 203 AVNLAFGALAKAAPALNPMQLGLPLTVLLGLFLLSSFASEFAPPVQRLFDSAFDAARAL 261 +NLA G L + AP L+ +G PLT+ +G+ L+++ AP + LF F+ + Sbjct: 196 TLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFCEHLFSEIFNLLADI 254
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 35.0 bits (80), Expect = 0.002 Identities = 21/59 (35%), Positives = 29/59 (49%), Gaps = 6/59 (10%) Query: 783 KLLARKQELEHL--IAERTAELEQDKRDLEAARAALTHKATHDELTGLLNRAGILEALR 839 +L A Q+LE I+E A + +RDL+A+R A K E L + I EA R Sbjct: 327 QLEAEHQKLEEQNKISE--ASRQSLRRDLDASREA--KKQLEAEHQKLEEQNKISEASR 381 Score = 33.9 bits (77), Expect = 0.003 Identities = 31/112 (27%), Positives = 43/112 (38%), Gaps = 20/112 (17%) Query: 783 KLLARKQELEHLIAERTAELEQDKRDLEAARAALTHKATHDELTGLLNRAGILEALRGML 842 L A K +LEH A + +RDL+A+R A K E L + I EA R L Sbjct: 292 ALEAEKADLEHQSQVLNANRQSLRRDLDASREAK--KQLEAEHQKLEEQNKISEASRQSL 349 Query: 843 --DSAPLREQPLAVVLIDLDYFKQVNDQHGHL-----AGDAVLAGVGKRLNA 887 D RE KQ+ +H L +A + + L+A Sbjct: 350 RRDLDASREA-----------KKQLEAEHQKLEEQNKISEASRQSLRRDLDA 390
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 340 bits (875), Expect = e-118 Identities = 103/344 (29%), Positives = 181/344 (52%), Gaps = 2/344 (0%) Query: 8 GERTELPTEKRLREAREQGNIPQSRELSTAAVFGTGVFALMLMARGIGDGASVWMKTALS 67 GE+TE PT K++R+AR++G + +S+E+ + A+ LM ++ + S M + Sbjct: 3 GEKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLM--LIP 60 Query: 68 PDPKMRENPMALFGHFGDLLLQLLWVMVPLIGICLAAGLVGPLLMSGLHFSGKAIMPDLN 127 + AL ++LL+ ++ PL+ + + ++ G SG+AI PD+ Sbjct: 61 AEQSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDIK 120 Query: 128 KLNPMNGIKRMWGSNSLAELVKSILRLLFVGLAASLCISKGLHGLRSLVNRPLEQAVGNG 187 K+NP+ G KR++ SL E +KSIL+++ + + + I L L L +E Sbjct: 121 KINPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLL 180 Query: 188 LDFTKSLLFYTAGALVLLAAFDAPYQKWNWLRKLKMTREEIKREMKESEGSPEVKGRIRQ 247 + L+ V+++ D ++ + ++++LKM+++EIKRE KE EGSPE+K + RQ Sbjct: 181 GQILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKRRQ 240 Query: 248 MQMQMSQRRMMEALPTADVVLMNPTHYAVALKYEGGKMRAPVVVAKGVDEMAFRIREACE 307 ++ R M E + + VV+ NPTH A+ + Y+ G+ P+V K D +R+ E Sbjct: 241 FHQEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIAE 300 Query: 308 QHRVAIVTAPPLARALYREAQLGKEIPVRLYSVVAQVLSYVYQL 351 + V I+ PLARALY +A + IP A+VL ++ + Sbjct: 301 EEGVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQ 344
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 92.6 bits (230), Expect = 3e-25 Identities = 31/105 (29%), Positives = 51/105 (48%), Gaps = 3/105 (2%) Query: 6 RILIVDDFSTMRRIVKNLLADLGFTNTAEAEDGNSALAALRAGPFDFVVTDWNMPGMTGI 65 IL+ DD + +R ++ L+ G+ + + + AG D VVTD MP Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 66 DLLRNIRADAKLKHLPVMMVTAEAKREQIIEAAQCGVNGYIIKPF 110 DLL I+ LPV++++A+ I+A++ G Y+ KPF Sbjct: 64 DLLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPF 106
>PF06580#Sensor histidine kinase Length = 349 Score = 44.1 bits (104), Expect = 1e-06 Identities = 24/136 (17%), Positives = 44/136 (32%), Gaps = 53/136 (38%) Query: 283 LVRNAIDHGIESPALREATGKPRSGHVRLSAQQEGDYVSIEIQDDGAGIDPERLREIARN 342 LV N I HGI P+ G + L ++ V++E+++ G+ Sbjct: 263 LVENGIKHGIA--------QLPQGGKILLKGTKDNGTVTLEVENTGSLALKN-------- 306 Query: 343 KGLIDAEAAARLSTDECLHLIFMPGFSTKAEVTDISGRGVGMDVVQSRIRELSG---QIQ 399 G G+ V+ R++ L G QI+ Sbjct: 307 ---------------------------------TKESTGTGLQNVRERLQMLYGTEAQIK 333 Query: 400 IQSELGRGSRFMIRVP 415 + + G+ M+ +P Sbjct: 334 LSEKQGKV-NAMVLIP 348
>PF05860#haemagglutination activity domain. Length = 117 Score = 76.8 bits (189), Expect = 2e-18 Identities = 23/134 (17%), Positives = 40/134 (29%), Gaps = 23/134 (17%) Query: 42 TPNPGGQQPGQQVAANGVPVVDIVAPNARGISHNRYSNFNVGPNGLILNNSAQISKTELG 101 TP+ +++ + H+ + F+V +G N+ Sbjct: 4 TPDTTLPINSNITTEGNTRIIERGTQAGSNLFHS-FQEFSVPTSGTAFFNNP-------- 54 Query: 102 GYVAGNNNLQRSGAASLILNEVTSAS-SRLQGYTEIAGAKAQLVIANPNGISCDGCGFLN 160 I++ VT S S + G A L + NPNGI L+ Sbjct: 55 ------------TNIQNIISRVTGGSVSNIDGLIRANA-TANLFLINPNGIIFGQNARLD 101 Query: 161 TSRVTLTTGAPNLG 174 + + A L Sbjct: 102 IGGSFVGSTANRLK 115
>RTXTOXINC#Gram-negative bacterial RTX toxin-activating protein C signature. Length = 170 Score = 54.9 bits (132), Expect = 2e-12 Identities = 30/124 (24%), Positives = 44/124 (35%), Gaps = 21/124 (16%) Query: 24 KKFSIAAAYVWLW-------------------PAIRLGQLVTIEDEDGVWTGYALWAYLT 64 K I WLW PAI+ Q V + D Y WA L+ Sbjct: 5 KPLEILGHVSWLWASSPLHRNWPVSLFAINVLPAIQANQYVLLTR-DDYPVAYCSWANLS 63 Query: 65 PETASHLVLQDPPFLPISDWNEGDQLWILDFVAMPGHHRRLARALRHRLRPHFKQAHRLV 124 E + D L DW GD+ W +D++A G + L + +R + +A R+ Sbjct: 64 LENEIKYL-NDVTSLVAEDWTSGDRKWFIDWIAPFGDNGALYKYMRKKFPDELFRAIRVD 122 Query: 125 RDKT 128 Sbjct: 123 PKTH 126
>PERTACTIN#Pertactin signature. Length = 922 Score = 37.8 bits (87), Expect = 3e-05 Identities = 33/100 (33%), Positives = 41/100 (41%), Gaps = 3/100 (3%) Query: 21 VDPSEPPTEIPPIVVNPPPSPPPTIPPSPPVEQPGPITPPGGGGGVPTPLPPLVSGLGAG 80 V PP P P P P P PP PP + P P PP P P PP L A Sbjct: 563 VGAKAPPAPKPAPQPGPQPGPQPPQPPQPP-QPPQPPQPPQRQPEAPAPQPPAGRELSAA 621 Query: 81 ADAYLNKSDEVKSLLSKYLAGGADVEFKDLGTVKGEVDAG 120 A+A +N V + + A + K LG ++ DAG Sbjct: 622 ANAAVNTGG-VGLASTLWYAESNALS-KRLGELRLNPDAG 659
>PF05272#Virulence-associated E family protein Length = 892 Score = 32.4 bits (73), Expect = 0.008 Identities = 19/65 (29%), Positives = 26/65 (40%), Gaps = 11/65 (16%) Query: 515 KWIMSALQLRA-----PAGQVIAIVGNSGVGKTTLIRVLAGLEDLQVGDFLVNGEDLRKV 569 K+I+ R + + G G+GK+TLI L GL DF + Sbjct: 578 KYILMGHVARVMEPGCKFDYSVVLEGTGGIGKSTLINTLVGL------DFFSDTHFDIGT 631 Query: 570 GKSSY 574 GK SY Sbjct: 632 GKDSY 636
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 127 bits (320), Expect = 2e-34 Identities = 67/423 (15%), Positives = 152/423 (35%), Gaps = 52/423 (12%) Query: 48 ALFLLLATFVLTASYSKREHVSGQIISTHGRVDIRSGTPGLILSTTLKPNALVKKGQVLA 107 + +L+ +G++ + +I+ ++ +K V+KG VL Sbjct: 69 VIAFILSVL---GQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLL 125 Query: 108 ELSADITD---------------EAGR----------------SLSDETIKRALTRSEEL 136 +L+A + E R L DE + ++ E L Sbjct: 126 KLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVL 185 Query: 137 TKEQLQTHDFS--GQRERELTRQVEETTGAMQEVARKISILEKKYAKNKELLKTIEPLLA 194 L FS ++ + +++ V +I+ E K L LL Sbjct: 186 RLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLH 245 Query: 195 EKYVSKYTYLTYENALLDAEAEIQDARAQQSTLRNQ----RAALLGEITEIKTTASRQAS 250 ++ ++K+ L EN ++A E++ ++Q + ++ + K + Sbjct: 246 KQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLR 305 Query: 251 EIEREKSTIEDQVARAKSD-RLQTITSPLSGTVAAIYA-SQGQRIGTDSIIASITPSESV 308 + + ++A+ + + I +P+S V + ++G + T + I P + Sbjct: 306 QTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDT 365 Query: 309 FEAEILIPSRAIGHVNVGTEVLLNIAAFPKAKYGAIQGRIASLSTQTSPIGELERRYGRQ 368 E L+ ++ IG +NVG ++ + AFP +YG + G++ +++ Sbjct: 366 LEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIE----------D 415 Query: 369 SPTEPVYTAKVALPSQTIGVAQEAKSFLPGMEVDAELILEGRKIWEWMFDPFQTMGSRLT 428 V+ +++ + + GM V AE+ R + ++ P + + Sbjct: 416 QRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGMRSVISYLLSPLEESVTESL 475 Query: 429 GEK 431 E+ Sbjct: 476 RER 478
>BICOMPNTOXIN#Staphylococcal bi-component toxin signature. Length = 315 Score = 31.8 bits (72), Expect = 0.006 Identities = 11/44 (25%), Positives = 21/44 (47%) Query: 460 QIVYAPREQQDANDYSDMLGYTTVRKKNKSHTSGKQSSVSYSET 503 I Y P+ + ++ + S LGY + + G S +YS++ Sbjct: 122 LINYLPKNKIESTNVSQTLGYNIGGNFQSAPSLGGNGSFNYSKS 165
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 40.8 bits (95), Expect = 3e-05 Identities = 36/167 (21%), Positives = 66/167 (39%), Gaps = 12/167 (7%) Query: 585 QQTKQNFQTRSAQVSKRLAELEALRQALSALPSLRQRE-EHASRQRADAEQSASTTMETW 643 + + A + R AELE + + + + ++A E + Sbjct: 245 SAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQS 304 Query: 644 QTAQSISTNARSQLEGSREALSQHERDRPGLFALKRLFGSISVKQWEAAHTPLAREHDQA 703 Q + + R L+ SREA Q E + L + IS EA+ L R+ D + Sbjct: 305 QVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNK----IS----EASRQSLRRDLDAS 356 Query: 704 QVAYRKLKSEEDAA---LQASEQARKAAHDTAASHVTAKDALDKALA 747 + A ++L++E + SE +R++ + AK ++KAL Sbjct: 357 REAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALE 403
>PERTACTIN#Pertactin signature. Length = 922 Score = 28.1 bits (62), Expect = 0.040 Identities = 27/104 (25%), Positives = 36/104 (34%), Gaps = 6/104 (5%) Query: 14 GPMIPPWADAPPAGGGDTPAPPPGTPPEPDAPSPQAQPQRWTGVRRNLGDFARNGDGRSL 73 G PP P G PP P P P P PQ R+ + GR L Sbjct: 564 GAKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQ-----RQPEAPAPQPPAGREL 618 Query: 74 RRAVKHYVRSGYGGAATASRRMSSTGSTANALGNALAGLGAGGF 117 A V +G G A+ + + + + + LG AGG Sbjct: 619 SAAANAAVNTGGVGLAS-TLWYAESNALSKRLGELRLNPDAGGA 661
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 33.6 bits (77), Expect = 0.001 Identities = 31/130 (23%), Positives = 44/130 (33%), Gaps = 9/130 (6%) Query: 72 FGMSDQAAFAAATFLGLF-----VGAALLSPFADRFGRRLVFTVALVWYTAATVAMGLQS 126 S+ L L+ A +L +DRFGRR V V+L M Sbjct: 35 LVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAP 94 Query: 127 TATAVIVLRFVVGIGLGIELVTIDTYLSELVPRHMRGAAFAF---AFFLQFLAVPSVALS 183 + + R V GI G Y++++ R F F F +A P + Sbjct: 95 FLWVLYIGRIVAGIT-GATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGL 153 Query: 184 AWLLVPHAPL 193 PHAP Sbjct: 154 MGGFSPHAPF 163
>TRNSINTIMINR#Translocated intimin receptor (Tir) signature. Length = 549 Score = 29.3 bits (65), Expect = 0.022 Identities = 16/61 (26%), Positives = 28/61 (45%) Query: 85 SGAAHVTHTLVTAPHQGAPGLFAVALDQPGIRIDASAWQALGMRAIETANVTFSATPAQL 144 SG+ VT L+ P QG +A+ + G+R+ + G A+ + N + P + Sbjct: 489 SGSGPVTGRLIGTPGQGIQSTYALLANSGGLRLGMGGLTSGGETAVSSVNAAPTPGPVRF 548 Query: 145 V 145 V Sbjct: 549 V 549
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 30.2 bits (68), Expect = 0.018 Identities = 18/67 (26%), Positives = 29/67 (43%), Gaps = 5/67 (7%) Query: 25 VVTDYSYDARGRLTASIVRGQDSGSETDDRIT--RYSYWPTGLVKQVALPGGDVSDFTYD 82 V++D+ + + A+ + S ET T YS+ + LVK+VA GG+V F Sbjct: 90 VLSDFELELQM---ANTNKTLASDLETVFLTTSTEYSFLSSSLVKEVARFGGNVEHFVPS 146 Query: 83 SAFRLTK 89 Sbjct: 147 HVAAALY 153
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 31.6 bits (71), Expect = 0.021 Identities = 19/66 (28%), Positives = 33/66 (50%), Gaps = 3/66 (4%) Query: 519 KEAQDRWERARKHFKQLSSACSTRLSQLENLRRALIQL---PKLREEEKAKRQQHLEASS 575 + + + +R+ KQ+ A S+L L + +L KL E+EKA+ Q LEA + Sbjct: 382 QSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEA 441 Query: 576 HANQAQ 581 A + + Sbjct: 442 KALKEK 447
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 55.5 bits (133), Expect = 2e-09 Identities = 35/263 (13%), Positives = 76/263 (28%), Gaps = 15/263 (5%) Query: 729 QASVAAQARQEREQQDRLAQEQHAAQVREHLHQAQPEREDQSQSEQAVQAHAMLEGQRQA 788 QA + + A P ++ +E + Q + + Sbjct: 998 TTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQ-------ESKT 1050 Query: 789 EQQREQ---EDHQQQERQAHTNQQRELQEREGREVQQRQAQERQSEDNQQREQQDRQAQE 845 ++ EQ E Q A + + EV Q ++ ++++ + +E + +E Sbjct: 1051 VEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEE 1110 Query: 846 TRQVEVQEAQAQQTHDQQQQTQGLEPRQASPQLDTQPHAPDAALVQQTPRPESQQED--- 902 +VE ++ Q Q + + PQ + +++ + D Sbjct: 1111 KAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQ 1170 Query: 903 -ARQQPQMRNQQAHEHLAPDAPDPLKQTHSPGDARPHQAQEAERALEMSAVESRAAARLQ 961 A++ Q E + + + + Q + R + R Sbjct: 1171 PAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSV 1230 Query: 962 VSSSEGP-ESGNQFSQGAEADAV 983 + E S N S A D Sbjct: 1231 PHNVEPATTSSNDRSTVALCDLT 1253 Score = 53.5 bits (128), Expect = 6e-09 Identities = 45/296 (15%), Positives = 95/296 (32%), Gaps = 22/296 (7%) Query: 647 RNESGQYGYDSPIVHLQRGSDGVARVVAVTSSDDIRQALNEAQGNRRELPPLARAPEATG 706 RN +G+Y +P V + +T+ ++I+ + N E+ + AP Sbjct: 972 RNVNGRYDLYNPEVEKRNQ---TVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPP 1028 Query: 707 ETDTSTSDSSNPQQVLYIQARMQASVAAQARQEREQQDRLAQEQHAAQVREHLHQAQPER 766 T + A + Q + E+ ++ A E AQ RE +A+ Sbjct: 1029 APATPSE-----------TTETVAENSKQESKTVEKNEQDATET-TAQNREVAKEAKSNV 1076 Query: 767 EDQ-SQSEQAVQAHAMLEGQRQAEQQREQEDHQQQERQAHTNQQRELQEREGREVQQRQA 825 + +E A E Q ++ + +++ + Q + +Q Q+ Sbjct: 1077 KANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQS 1136 Query: 826 QERQSEDNQQREQ------QDRQAQETRQVEVQEAQAQQTHDQQQQTQGLEPRQASPQLD 879 + Q + RE ++ Q+Q + ++ + + + +Q + Sbjct: 1137 ETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVV 1196 Query: 880 TQPHAPDAALVQQTPRPESQQEDARQQPQMRNQQAHEHLAPDAPDPLKQTHSPGDA 935 P A Q T ES + + + H + T + D Sbjct: 1197 ENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDL 1252 Score = 44.7 bits (105), Expect = 3e-06 Identities = 44/280 (15%), Positives = 85/280 (30%), Gaps = 34/280 (12%) Query: 571 QMRQPSLERSQEALTAIQALPAPTATQMEHNELLHRYRAAGVDLNVNPQTQQAVELASQR 630 Q PS+ + E + + P P +E V N Q + VE Q Sbjct: 1004 QADVPSVPSNNEEIARVDEAPVPPPAPATPSE-----TTETVAENS-KQESKTVEKNEQD 1057 Query: 631 TRDASGIAGPTMQQLQRNESGQYGYDSPIVHLQRGSDGVARVVAVTSSDDIRQALNEAQG 690 + + ++ + N V A T ++++ Q+ +E + Sbjct: 1058 ATETTAQNREVAKEAKSN-----------------------VKANTQTNEVAQSGSETKE 1094 Query: 691 NRR----ELPPLARAPEATGETDTSTSDSSNPQQVLYIQARMQASVAAQARQEREQQDRL 746 + E + + +A ET+ + QV Q + + V QA RE + Sbjct: 1095 TQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSET-VQPQAEPARENDPTV 1153 Query: 747 AQEQHAAQVREHLHQAQPEREDQSQSEQAVQAHAMLEGQRQAEQQREQEDHQQQERQAHT 806 ++ +Q QP +E S EQ V + + E + ++ Sbjct: 1154 NIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNS 1213 Query: 807 NQQRELQEREGREVQQRQAQERQSEDNQQREQQDRQAQET 846 + + R R V+ + + T Sbjct: 1214 ESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLT 1253 Score = 43.1 bits (101), Expect = 1e-05 Identities = 25/220 (11%), Positives = 64/220 (29%), Gaps = 7/220 (3%) Query: 682 RQALNEAQGNRRELPPLARAPEATGETDTSTSDSSNPQQVLYIQARMQASVAAQARQERE 741 Q E RE+ A+ ++ + +T T++ + + A +E + Sbjct: 1055 EQDATETTAQNREV---AKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEK 1111 Query: 742 QQDRLAQEQHAAQVREHL--HQAQPEREDQSQSEQAVQAHAMLEGQRQAEQQREQEDHQQ 799 + + Q +V + Q Q E + + Q++ D +Q Sbjct: 1112 AKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNT-TADTEQ 1170 Query: 800 QERQAHTNQQRELQEREGREVQQRQAQERQSEDNQQREQQDRQA-QETRQVEVQEAQAQQ 858 ++ +N ++ + E + ++ + + + + Sbjct: 1171 PAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSV 1230 Query: 859 THDQQQQTQGLEPRQASPQLDTQPHAPDAALVQQTPRPES 898 H+ + T R D +A L + + Sbjct: 1231 PHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQF 1270 Score = 35.8 bits (82), Expect = 0.001 Identities = 39/302 (12%), Positives = 91/302 (30%), Gaps = 10/302 (3%) Query: 981 DAVPPALPPSVQTQQAEMEQASVRQQDVARKQEAEQVRVMAQTAPATAEPLIASQPPAPT 1040 V + QA++ +++AR EA T T E + + Sbjct: 990 QTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESK 1049 Query: 1041 TLERAAEARQASPSDVSPIDHGAAVLPAINLAQAHGQSLGGSAENRFPT---EPADAESQ 1097 T+E+ + + + + A N G + T E A E + Sbjct: 1050 TVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKE 1109 Query: 1098 QAQSTPAQDRSAADPGGALFLEETMRSLRQLQQEIEAADREDERFHQEWKEYRERGEPYP 1157 + +++ P + +Q + E A D + KE + + Sbjct: 1110 EKAKVET-EKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNI--KEPQSQTNTTA 1166 Query: 1158 FVRDGARDQESGSIDAFSAHQPSRRSPSEAAEQTDAFPSLAQRFAGPGGGDAPNDSSKDE 1217 A++ S + S + P+ Q + P + + Sbjct: 1167 DTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRS 1226 Query: 1218 RKSITGDPDVDEVLYALDSKNELAIEQALNRVANSAATQALLKKGNDFLEAQAQQEAQEH 1277 +S+ + + + + ++ +A+ + N+ + A K F+ + +H Sbjct: 1227 VRSVPHNVEPATT--SSNDRSTVALCDLTSTNTNAVLSDARAKA--QFVALNVGKAVSQH 1282 Query: 1278 VA 1279 ++ Sbjct: 1283 IS 1284
>cloacin#Cloacin signature. Length = 551 Score = 34.3 bits (78), Expect = 7e-04 Identities = 25/129 (19%), Positives = 57/129 (44%), Gaps = 20/129 (15%) Query: 4 DQRRRDVERHQKEIARLQTEKSREETKAVGEKKKAFDASAAATRTKSVSTQQSKLREAQR 63 ++ R ++ + +++AR Q E+ + + +K DA+ K+++ +++++ R Sbjct: 324 ERARAELNQANEDVARNQ-ERQAKAVQVYNSRKSELDAA-----NKTLADAIAEIKQFNR 377 Query: 64 YEGNAVA--------IQKKIADLETKIAREHERLGNANRQLSAAQV-----QEQKKQVQE 110 + + +A K +T + + A ++ S A E +K+ +E Sbjct: 378 FAHDPMAGGHRMWQMAGLKAQRAQTDVNNKQAAFDAAAKEKSDADAALSSAMESRKK-KE 436 Query: 111 DKKRDAERK 119 DKKR AE Sbjct: 437 DKKRSAENN 445
>adhesinb#Adhesin B signature. Length = 310 Score = 27.9 bits (62), Expect = 0.008 Identities = 10/32 (31%), Positives = 15/32 (46%) Query: 1 MKHARIGLVALTMALGLTACGGKPSSDNAKEA 32 MK R ++ L +GL AC + SS + Sbjct: 1 MKKCRFLVLLLLAFVGLAACSSQKSSTETGSS 32
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 62.8 bits (152), Expect = 5e-12 Identities = 58/355 (16%), Positives = 124/355 (34%), Gaps = 16/355 (4%) Query: 150 SQIIEARPEDLRVYLEEAAG-ISKYKERRKETETRIRHTRENLDRLGDLREEITKQLAHL 208 + + + L+ + +E +S KE+ ++ + + + L + ++ K L Sbjct: 73 NSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGA 132 Query: 209 QRQARQAE-QYQALQEERRIKDAEWKALEY--RGLDGRLQGLREKLNQEETRLQQLIAEQ 265 + + + L+ E+ A LE G K+ E L A Q Sbjct: 133 MNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQ 192 Query: 266 RDAEARIETGRVRREEAAEAVAKAQADVYQVGGALARIEQQIQHQRELSHRLHKARDEAQ 325 + E +E + + +A+ + A +E+ ++ S + Sbjct: 193 AELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLE 252 Query: 326 SQLQELTQHISGDSAKLAVLREAVADAEPQLEQLREDHEFRQDALREAEARLADWQQRWE 385 ++ L + L +++ L + + + E + + Sbjct: 253 AEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQ 312 Query: 386 THNRDTGEASRAGEVERTRVDYLDRQSLEADRRREALVNERAGLDLDALAEAFEQIELRH 445 + RD + A + L+ Q+ ++ R++L DLDA EA +Q+E Sbjct: 313 SLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRR-----DLDASREAKKQLE--- 364 Query: 446 ETQKASLDGLTEQVEARKHALGGLQEQQRASQGELAEVRKQAQAARGRLSSLETL 500 A L EQ + + + L+ AS+ +V K + A +L++LE L Sbjct: 365 ----AEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKL 415 Score = 40.4 bits (94), Expect = 4e-05 Identities = 36/190 (18%), Positives = 76/190 (40%), Gaps = 13/190 (6%) Query: 657 EREIQELRSQIDTLQEREGDLEEQLASFREQLLAAEQQREDAQRQLYMAHRSVSELAGQL 716 E E L ++ L++ + ++ E ++ + + L Sbjct: 252 EAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANR 311 Query: 717 QSQQGKVDAARGRIERIEAELGQLLETLDTSR----------EQAREARAKLEDAVVRMG 766 QS + +DA+R +++EAE +L E S + +REA+ +LE + Sbjct: 312 QSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQK-- 369 Query: 767 DLQGTREALESERRQLTDARDQARDAARGVRDAMHALALTLESQRTQITSLSQTLERMDS 826 L+ + E+ R+ L D +R+A + V A+ L + L ++ + + Sbjct: 370 -LEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEK 428 Query: 827 QRGQLDTRLE 836 ++ +L +LE Sbjct: 429 EKAELQAKLE 438 Score = 36.6 bits (84), Expect = 5e-04 Identities = 33/197 (16%), Positives = 74/197 (37%), Gaps = 7/197 (3%) Query: 657 EREIQELRSQIDTLQEREGDLEEQLASFREQLLAAEQQREDAQRQLYMAHRSVSELAGQL 716 E+ ++ + + LE + A+ + E+ E A + L + Sbjct: 231 EKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEK 290 Query: 717 QSQQGKVDAARGRIERIEAELGQLLETLDTSREQAREARAKLEDAVVRMGDLQGTREALE 776 + + + + + + A L LD SRE ++ A+ + L+ + E Sbjct: 291 AALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQ-------KLEEQNKISE 343 Query: 777 SERRQLTDARDQARDAARGVRDAMHALALTLESQRTQITSLSQTLERMDSQRGQLDTRLE 836 + R+ L D +R+A + + L + SL + L+ + Q++ LE Sbjct: 344 ASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALE 403 Query: 837 DLVAQLSEGDSPVETLE 853 + ++L+ + + LE Sbjct: 404 EANSKLAALEKLNKELE 420 Score = 36.6 bits (84), Expect = 7e-04 Identities = 43/294 (14%), Positives = 99/294 (33%), Gaps = 13/294 (4%) Query: 715 QLQSQQGKVDAARGRIERIEAELGQLLETLDTSREQAREARAKLEDAVVRMGDLQGTREA 774 L+ Q + D ++ + L ++ E +L +A ++ + Sbjct: 51 TLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSE 110 Query: 775 LESERRQLTDARDQARDAARGVRDAMHALALTLESQRTQITSLSQTLERMDSQRGQLDTR 834 S+ ++L + A + + ++ + + L +++ L+ Sbjct: 111 KASKIQELEARKADLEKA----LEGAMNFSTADSAKIKTLEAEKAALA---ARKADLEKA 163 Query: 835 LEDLVAQLSEGDSPVETLEHEHQAALSERVRTERVLGEARTMLDSIDGELRSFEQTRQQR 894 LE + + + ++TLE E A + + E+ L A + + +T + Sbjct: 164 LEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGA----MNFSTADSAKIKTLEAE 219 Query: 895 DEQALAQRERISQRKLDQQALVLNAEQLAAAVVKAGFVLEDVVNGLEEAANPAEWDAAVG 954 A++ + + + LE LE+A A Sbjct: 220 KAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAM--NFST 277 Query: 955 QIDARMRRLEPVNLAAIQEYGEAAQRSEYLDAQNVDLTTALETLEEAIRKIDRE 1008 A+++ LE A E + +S+ L+A L L+ EA ++++ E Sbjct: 278 ADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAE 331
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 45.3 bits (107), Expect = 7e-08 Identities = 26/77 (33%), Positives = 35/77 (45%), Gaps = 6/77 (7%) Query: 83 ADQRISFPTVGTFGFNSYRLPAEADGALAQLVPAVLNAADGELGKKWLKQVVVEGYTDTK 142 + + + F FN L E AL QL + L+ D + G VVV GYTD Sbjct: 211 QTKHFTLKSDVLFNFNKATLKPEGQAALDQLY-SQLSNLDPKDGS-----VVVLGYTDRI 264 Query: 143 GGYLYNLHLSLQRSEWV 159 G YN LS +R++ V Sbjct: 265 GSDAYNQGLSERRAQSV 281
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 277 bits (711), Expect = 8e-94 Identities = 72/225 (32%), Positives = 113/225 (50%), Gaps = 8/225 (3%) Query: 227 AAARSLGEQKGVALPPPPGGLEDLPVVELPARGDGDNDDDTFAIFVSGDGGWAGLDEEVA 286 + A + ++ L +E V + IF+SGDGGWA LD+ V Sbjct: 16 STANAFADEFADNLGLTLLPVEPSTQVNAASSHTKP----PLVIFLSGDGGWATLDKAVG 71 Query: 287 DALVAQGIPVVGLDSLRYFWSERTPQGFATDLDRIARFYAQRWQRRRVVLIGFSQGADVL 346 L QG PVVG SL+Y+W ++ P+ D I Y + ++V+LIG+S GA+V+ Sbjct: 72 GILQQQGWPVVGWSSLKYYWKQKDPKDVTQDTLAIIDKYQAEFGTQKVILIGYSFGAEVI 131 Query: 347 PAAINKLPAPTKQNLRMTALLSVGKLADYEFHVSNWLGSDDDG--LPIAPEVQRLPPGIT 404 P +N++PA ++N+ LLS + +D+E HVS + SD+ PEV + Sbjct: 132 PFVLNEMPARYRKNVLGAVLLSPSQSSDFEIHVSEMVTSDNQSARYLTLPEVNKQTTVPM 191 Query: 405 VCIYGQDDEDA--LCPSLPAETAKRVVLPGDHHFKGDYATLAKVI 447 +C+YG++D+ LCP + + L G H F DY + K+I Sbjct: 192 LCLYGKEDDAPLHLCPEVKQPNVTVMELSGGHSFDDDYDKVVKLI 236
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 324 bits (831), Expect = e-105 Identities = 103/309 (33%), Positives = 159/309 (51%), Gaps = 16/309 (5%) Query: 300 ASVWPEMSQARRDAPLAVDAGS---GGELASDAPVIEADPRTNGILIRDRPERMAAYGTL 356 A++ + + VD AS +EADP N I++RD PERM Y L Sbjct: 212 ATILQRVLSDATIQQVTVDNQRIPQAATRASAQARVEADPSLNAIIVRDSPERMPMYQRL 271 Query: 357 IQQLDNRPKLLQIDATIIEIRDGALQDLGVDWRFHSRRVDVQTGDGRGGQLGYDGSLSGA 416 I LD +++ +I++I L +LGVDWR V ++TG+ + G S Sbjct: 272 IHALDKPSARIEVALSIVDINADQLTELGVDWR-----VGIRTGNNHQVVIKTTGDQSNI 326 Query: 417 AAAGAAAPLGGTLTAVLGDAGRYLMTRVSALEQTNKAKIVSTPQVATLDNVEAVMDHKQQ 476 A+ GA G+L G YL+ RV+ LE A++VS P + T +N +AV+DH + Sbjct: 327 ASNGAL----GSLVDARGL--DYLLARVNLLENEGSAQVVSRPTLLTQENAQAVIDHSET 380 Query: 477 AFVRVSGYASADLYNLSAGVSLRVLPSVVPGSPNGQMRLDVRIEDGQLGANT--VDGIPV 534 +V+V+G A+L ++ G LR+ P V+ ++ L++ IEDG N+ ++GIP Sbjct: 381 YYVKVTGKEVAELKGITYGTMLRMTPRVLTQGDKSEISLNLHIEDGNQKPNSSGIEGIPT 440 Query: 535 ITSSEITTQAFVNEGQSLLIAGYASDTDQTDLNNVPGLSRIPLVGNLFKHRQQSGSRLQR 594 I+ + + T A V GQSL+I G D L+ VP L IP +G LF+ + + R R Sbjct: 441 ISRTVVDTVARVGHGQSLIIGGIYRDELSVALSKVPLLGDIPYIGALFRRKSELTRRTVR 500 Query: 595 LFLLTPHIV 603 LF++ P I+ Sbjct: 501 LFIIEPRII 509 Score = 236 bits (604), Expect = 5e-72 Identities = 68/230 (29%), Positives = 113/230 (49%), Gaps = 5/230 (2%) Query: 16 LAAALLLGLLPLLPPHANAASVPWHSRSFKYVADRKDLKEVLRDLSASQSITTWISPEVT 75 +L G L LL ++ A + W + YVA + L+++L D A+ T +S ++ Sbjct: 8 FFKRVLTGTLLLLSSYSWAQELDWLPIPYVYVAKGESLRDLLTDFGANYDATVVVSDKIN 67 Query: 76 GTLSGKFEA-TPQKFLDDLSGTFGFVWYYDGSVLRIWGANETKNATLSLGAASTSALRDA 134 +SG+FE PQ FL ++ + VWYYDG+VL I+ +E + + L + + L+ A Sbjct: 68 DKVSGQFEHDNPQDFLQHIASLYNLVWYYDGNVLYIFKNSEVASRLIRLQESEAAELKQA 127 Query: 135 LARMRLDDPRFPVRYDETAHLAVVSGPPGYVDTVAAIAKQVEQVARQR----DATEVQVF 190 L R + +PRF R D + L VSGPP Y++ V A +EQ + R A +++F Sbjct: 128 LQRSGIWEPRFGWRPDASNRLVYVSGPPRYLELVEQTAAALEQQTQIRSEKTGALAIEIF 187 Query: 191 QLHYAQAADHTTRIGGQDIQVPGMASLLRNIYGVRGAPTAALPGPGANFG 240 L YA A+D T ++ PG+A++L+ + + Sbjct: 188 PLKYASASDRTIHYRDDEVAAPGVATILQRVLSDATIQQVTVDNQRIPQA 237
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 169 bits (431), Expect = 6e-54 Identities = 51/240 (21%), Positives = 104/240 (43%), Gaps = 3/240 (1%) Query: 8 LLALSSQGVSLLTLLALCGVRVFVLFFVLPATAQDSLPGMTRNGVIYVLSSFIAYGQPAD 67 L S Q +S L L +RV L P ++ S+P + G+ +++ IA PA+ Sbjct: 2 LQVTSEQWLSWLNLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPAN 61 Query: 68 ALARIEAAGLVGLVFKEAFIGLLIGFAASTVFWVAESVGLLIDDVSGYNNVQMINPLSGE 127 + L L ++ IG+ +GF F + G +I G + ++P S Sbjct: 62 DVPVFSFFAL-WLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHL 120 Query: 128 QSTPVSTVLMQLAIVSFYALGGMLMLLGALFESFRWWPLSQLMPDMGAIGESFVIQQTDG 187 ++ ++ LA++ F G L L+ L ++F P+ + + + + Sbjct: 121 NMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGG--EPLNSNAFLALTKAGSL 178 Query: 188 MMAAIVKLSAPVMLVLVLVDLAIGFVARAADKLDPSNLSQPIRGVLALLLLALLTSVFIA 247 + + L+ P++ +L+ ++LA+G + R A +L + P+ + + L+A L + Sbjct: 179 IFLNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAP 238
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 29.8 bits (66), Expect = 0.008 Identities = 31/109 (28%), Positives = 43/109 (39%), Gaps = 9/109 (8%) Query: 114 RLAEIVAHACEQVLHGHDPA----ALYARAAQALDGALDEANALQVSVHPDALDDARRAF 169 RL ++ A QV+ G P AL + Q L + Q+ VHPD L Sbjct: 119 RLMQMALEAARQVI-GQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDML 177 Query: 170 DAAAAAGGWSMPVELCGDTTLALGACVCEWDTGVFETDLRDQLRSLRRV 218 A + GW L GD TL G C D G + + + + L R+ Sbjct: 178 GATLSLHGW----RLRGDPTLHPGGCKVSADEGDLDASVATRWQELCRL 222
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 81.2 bits (200), Expect = 1e-19 Identities = 37/165 (22%), Positives = 71/165 (43%), Gaps = 8/165 (4%) Query: 23 LYSGLTENDANDMLAVLLTAGVDAEKLTPDDGKTWAVNAPHDQVAYALNVLRTHGMPHER 82 L+S L++ D ++A L + G A+ P D+V L G+P + Sbjct: 53 LFSNLSDQDGGAIVAQLTQMNIPYR-FANGSG---AIEVPADKVHELRLRLAQQGLP--K 106 Query: 83 HANLG-EMFKKDGLISTPTEERVRFIYGVSQQLSQTLSNIDGVIAADVQIVLPNNDPLSA 141 +G E+ ++ + E+V + + +L++T+ + V +A V + +P Sbjct: 107 GGAVGFELLDQEKFGISQFSEQVNYQRALEGELARTIETLGPVKSARVHLAMPKPSLFVR 166 Query: 142 SVKPSSAAVFIKFRVGSDLT-SLVPSIKTLVMHSVEGLTYENVSV 185 K SA+V + G L + ++ LV +V GL NV++ Sbjct: 167 EQKSPSASVTVTLEPGRALDEGQISAVVHLVSSAVAGLPPGNVTL 211
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 332 bits (854), Expect = e-115 Identities = 110/349 (31%), Positives = 190/349 (54%), Gaps = 2/349 (0%) Query: 1 MSDEKTEKPTEKKLQDARRDGEVPISPDVTAAAVLLAALLVMKLAGSYFVEHLRALMSIG 60 MS EKTE+PT KK++DAR+ G+V S +V + A+++A ++ Y+ EH LM I Sbjct: 1 MSGEKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLMLIP 60 Query: 61 FDFTTNTRDATALHRALGRIGIQGVLLTLPFVTACLAAGLIGTFVQTGLNASLKPVTPKF 120 + + + AL + + ++ L P +T + VQ G S + + P Sbjct: 61 AE-QSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDI 119 Query: 121 DSLNPVNGVKKLFSLRSLINLLKLGIKAAVIGVVLWYGLRALMPTIIGLAYQPPADIAQI 180 +NP+ G K++FS++SL+ LK +K ++ +++W ++ + T++ L I + Sbjct: 120 KKINPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPL 179 Query: 181 GWRALGILCALAVLVFVLVGAADWSVQHWLFIRDKRMSKDEQKREHKESEGDPEVKGKRK 240 + L L + + FV++ AD++ +++ +I++ +MSKDE KRE+KE EG PE+K KR+ Sbjct: 180 LGQILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKRR 239 Query: 241 EFAKELVFGDPRERVAKAKVMVVNPTHYAVALAYEPDGFGLPQVVAKGVDEGALELRAYA 300 +F +E+ + RE V ++ V+V NPTH A+ + Y+ LP V K D +R A Sbjct: 240 QFHQEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIA 299 Query: 301 HNQGIPIVANPPLARAL-HEVELGEAVPESLFETVAVVLRWVDELGRDN 348 +G+PI+ PLARAL + + +P E A VLRW++ + Sbjct: 300 EEEGVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQNIEK 348
>TYPE3OMOPROT#Type III secretion system outer membrane O protein family signature. Length = 303 Score = 53.5 bits (128), Expect = 3e-10 Identities = 41/177 (23%), Positives = 77/177 (43%), Gaps = 15/177 (8%) Query: 144 PSPLPAWLSALRVTTRLRIGQRTATAALLQSLRPGDVLLHALATAPVRSGELLWGIPGGA 203 P+ LR R IG +LL + GDVLL + A V G Sbjct: 138 PAVGGGRPKMLRWPLRFVIGSSDTQRSLLGRIGIGDVLLIRTSRAEVYCYAKKLG----- 192 Query: 204 VLRAPVRLTLQQMILETAPTMQHDMPASDSSSSATDVAAL-ELPVQLEVD--QLALSLSV 260 ++ I+ +QH ++++ +A + L +LPV+LE + ++L+ Sbjct: 193 -----HFNRVEGGIIVETLDIQHIEEENNTTETAETLPGLNQLPVKLEFVLYRKNVTLAE 247 Query: 261 LSGLQPGQILELSVPVDQADIRLVVYGQTIGIGRLLAVGEHLGVQILS-MSETAHAD 316 L + Q+L L + ++ ++ G +G G L+ + + LGV+I +SE+ + + Sbjct: 248 LEAMGQQQLLSLPTNAEL-NVEIMANGVLLGNGELVQMNDTLGVEIHEWLSESGNGE 303
>TYPE3IMPPROT#Type III secretion system inner membrane P protein family signature. Length = 224 Score = 245 bits (626), Expect = 7e-85 Identities = 80/219 (36%), Positives = 132/219 (60%), Gaps = 8/219 (3%) Query: 3 MPDVGSLLLVVIMLGLLPFAAMVVTSYTKIVVVLGLLRNAIGVQQVPPNMVLNGVALLVS 62 M + SL+ ++ LLPF T + K +V ++RNA+G+QQ+P NM LNGVALL+S Sbjct: 1 MGNDISLIALLAFSTLLPFIIASGTCFVKFSIVFVMVRNALGLQQIPSNMTLNGVALLLS 60 Query: 63 CFVMAPVGMEAFKAAQNYSPGADN-SRVVVLLDACREPFRQFLLKHTREREKAFFIRSAQ 121 FVM P+ +A+ ++ ++ S + +D + +R +L+K++ FF + Sbjct: 61 MFVMWPIMHDAYVYFEDEDVTFNDISSLSKHVDEGLDGYRDYLIKYSDRELVQFFENAQL 120 Query: 122 QIWPKDKA-------DTLKPDDLLVLAPAFTLSELTEAFRIGFLLYLVFIVIDLVVANAL 174 + ++ D ++ + L PA+ LSE+ AF+IGF LYL F+V+DLVV++ L Sbjct: 121 KRQYGEETETVKRDKDEIEKPSIFALLPAYALSEIKSAFKIGFYLYLPFVVVDLVVSSVL 180 Query: 175 MAMGLSQVTPTNVAIPFKLLLFVALDGWSMLIHGLVLSY 213 +A+G+ ++P ++ P KL+LFVALDGW++L GL+L Y Sbjct: 181 LALGMMMMSPVTISTPIKLVLFVALDGWTLLSKGLILQY 219
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 62.5 bits (152), Expect = 9e-17 Identities = 24/78 (30%), Positives = 43/78 (55%) Query: 4 DDLVRFTSEALLLCLKVSLPVVGVAAVAGLLIAFIQAVMSLQDASISFALKLVVVVAAIA 63 DDLV ++AL L L +S VA + GLL+ Q V LQ+ ++ F +KL+ V + Sbjct: 2 DDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLF 61 Query: 64 VTAPWGASAIMQFGQALM 81 + + W ++ +G+ ++ Sbjct: 62 LLSGWYGEVLLSYGRQVI 79
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 29.7 bits (66), Expect = 0.018 Identities = 17/48 (35%), Positives = 21/48 (43%), Gaps = 8/48 (16%) Query: 14 LQPQDQPFSDGQPPTNPNPTPPMPPSRPPCSTNPGGQHGSGTGDGSGG 61 L P P +DGQP T P+ P P R P G+H +G G Sbjct: 359 LNPDANPDTDGQPGTRPD--SPAVPDR------PNGRHRKERKEGEDG 398
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 69.3 bits (169), Expect = 8e-17 Identities = 30/94 (31%), Positives = 49/94 (52%), Gaps = 3/94 (3%) Query: 21 PRPPRADAQRNKTHILEVASDAFAEEGI-NVSMDSIAKRAGVGPGTLYRHFPSREALLAA 79 R + +AQ + HIL+VA F+++G+ + S+ IAK AGV G +Y HF + L + Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 80 LLETHHANIEQVRMAITAEEHDPGCALQRWIEAL 113 + E +NI + + + + PG L E L Sbjct: 62 IWELSESNIGE--LELEYQAKFPGDPLSVLREIL 93
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 83.9 bits (207), Expect = 3e-21 Identities = 69/269 (25%), Positives = 105/269 (39%), Gaps = 20/269 (7%) Query: 1 MKQPGFEDKHVLITGGAGGIGIELIRVFANASCRVT-FTHRPGEDSRRRALDLVAAFGDD 59 M G E K ITG A GIG + R A+ + + P + + + A + Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE 60 Query: 60 RVHAHALDVGDRRSHAAFMQALTMPVDIVIHNAGVGTKTVERAAATY---KEQDEAFFRV 116 A D A ++ P+DI+++ AGV R + E+ EA F V Sbjct: 61 AFPADVRDSAAIDEITARIEREMGPIDILVNVAGV-----LRPGLIHSLSDEEWEATFSV 115 Query: 117 NTIGPLWLSEDLIPGMQARGQGKILFMSSVDGGITHFPRFR-AADGMSKAAVAFLGRQLA 175 N+ G S + M R G I+ + S PR AA SKAA + L Sbjct: 116 NSTGVFNASRSVSKYMMDRRSGSIVTVGS---NPAGVPRTSMAAYASSKAAAVMFTKCLG 172 Query: 176 ATLACTGIDVFTVCPGATDTPMFQASTLNALSPQQR-----QELEASLPGGRLIEPREIA 230 LA I V PG+T+T M + + +Q + + +P +L +P +IA Sbjct: 173 LELAEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIA 232 Query: 231 DLCFYLCRDEAR--ILRGAVIDASLGLGV 257 D +L +A + +D LGV Sbjct: 233 DAVLFLVSGQAGHITMHNLCVDGGATLGV 261
>PERTACTIN#Pertactin signature. Length = 922 Score = 28.5 bits (63), Expect = 0.039 Identities = 40/148 (27%), Positives = 54/148 (36%), Gaps = 10/148 (6%) Query: 30 GRVLIVGGSARVP-GAVMLAGEAALRAGAGKLQLA---TAASVAPGMAL-----AMPEAL 80 RV + GGS P G V+ G A R L+ A + A G AL P L Sbjct: 322 ARVTVSGGSLSAPHGNVIETGGGARRFPPPASPLSITLQAGARAQGRALLYRVLPEPVKL 381 Query: 81 VLGLGENGQGEIVR-GHRALDAAMSACDAAVIGPGMASTNTTAALVKRAIDQAVCTLVLD 139 L G GQG+IV + A S + T T A+ +ID A + + Sbjct: 382 TLAGGAQGQGDIVATELPPIPGASSGPLDVALASQARWTGATRAVDSLSIDNATWVMTDN 441 Query: 140 AGALSPRLRAPLGRPFVLTPHAGEMAAL 167 + + RL + F AG L Sbjct: 442 SNVGALRLASDGSVDFQQPAEAGRFKVL 469
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 44.2 bits (104), Expect = 9e-08 Identities = 20/68 (29%), Positives = 32/68 (47%) Query: 8 RTAKQREELLVDEVLDAAERCIDEIGLSATSFELIAERARLSCGTLLQRFEDKDALVRAL 67 R KQ + +LD A R + G+S+TS IA+ A ++ G + F+DK L + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 68 LERNYMRA 75 E + Sbjct: 63 WELSESNI 70
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 322 bits (828), Expect = e-107 Identities = 139/415 (33%), Positives = 202/415 (48%), Gaps = 34/415 (8%) Query: 142 EDARDCIADLRA--SGIQVIVGTGMA-IDFAEQAGLPGVLLYSADSVRLALDQAIALATA 198 E+A D + ++ + V+V + A +A G Y L + I + Sbjct: 60 ENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKP--FDLTELIGIIGR 117 Query: 199 PSSAAPALRNATRRTRNQPAALLGEDTAMVQVRALVQLYAPHASTVLISGETGTGKELVA 258 + + L+G AM ++ ++ T++I+GE+GTGKELVA Sbjct: 118 ALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVA 177 Query: 259 RQLHAGSRRRGR-FVAINCGAITESLLEAELFGYSDGAFTGARRGGHTGLIEAAQDGTLF 317 R LH +RR FVAIN AI L+E+ELFG+ GAFTGA+ TG E A+ GTLF Sbjct: 178 RALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTR-STGRFEQAEGGTLF 236 Query: 318 LDEIGELPLPLQTRLLRVLEEREVLRVGATVPVPVDVRVVAASLQPLQTLVDQGRFRRDL 377 LDEIG++P+ QTRLLRVL++ E VG P+ DVR+VAA+ + L+ ++QG FR DL Sbjct: 237 LDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDL 296 Query: 378 FYRLAALRIDLPPLRNRPDDIALLLTHYAQHGSETALP---LSPAALQRLQQHAWPGNVR 434 +YRL + + LPPLR+R +DI L+ H+ Q + L AL+ ++ H WPGNVR Sbjct: 297 YYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVR 356 Query: 435 ELRNLVERLCI---------------------HWKAQAQGQVSLAQLEAWAPELADASTP 473 EL NLV RL + S + + A E Sbjct: 357 ELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYF 416 Query: 474 AGYDSTSADAASSRAHLTAT---LVRAALERAQGNRASAAKALGVSRTTLWRWMQ 525 A + + L L+ AAL +GN+ AA LG++R TL + ++ Sbjct: 417 ASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIR 471
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 29.5 bits (66), Expect = 0.019 Identities = 13/34 (38%), Positives = 20/34 (58%) Query: 122 FTLVEGWNFRQLRAALGTATPLQQTIAGLDDAAL 155 ++LV+G RQL A +A P + T+A +D A Sbjct: 232 YSLVQGSTARQLAAVPSSADPSRTTVAYVDGTAG 265
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 117 bits (294), Expect = 2e-38 Identities = 54/88 (61%), Positives = 67/88 (76%) Query: 2 NKTELIDGVAAAADISKAEAGRAVDAVVSEITKALKKGDAVTLVGFGTFQVRERAERTGR 61 NK +LI VA A +++K ++ AVDAV S ++ L KG+ V L+GFG F+VRERA R GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 62 NPKTGDSIKIAASKNPAFKAGKALKDAV 89 NP+TG+ IKI ASK PAFKAGKALKDAV Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAV 90
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 32.1 bits (73), Expect = 0.009 Identities = 31/124 (25%), Positives = 51/124 (41%), Gaps = 21/124 (16%) Query: 333 ERILEYLAVQSRVKQMKGPILCLVGPPGVGKTSLGQSIAKATNRK---FVRMSLGGVRD- 388 + E V +R+ Q ++ + G G GK + +++ R+ FV +++ + Sbjct: 144 AAMQEIYRVLARLMQTDLTLM-ITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRD 202 Query: 389 --EAEIRGHRRTY----VGSMPGRLVQNLNKVGSKNPLFLLDEIDKMSMDFRGDPSSALL 442 E+E+ GH + GR Q LFL DEI M MD + + LL Sbjct: 203 LIESELFGHEKGAFTGAQTRSTGRFEQ-----AEGGTLFL-DEIGDMPMDAQ----TRLL 252 Query: 443 EVLD 446 VL Sbjct: 253 RVLQ 256
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 32.1 bits (73), Expect = 0.005 Identities = 15/85 (17%), Positives = 32/85 (37%), Gaps = 10/85 (11%) Query: 60 QSARSSLPKPREILEVLDQY----VIGQLRAKRTLAVAVYNHYKRIESRSKNDEVELAK- 114 + A LPKP ++ E++ + R + + S + + + Sbjct: 96 KGAYDYLPKPFDLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLAR 155 Query: 115 -----SNILLVGPTGSGKTLLAETL 134 +++ G +G+GK L+A L Sbjct: 156 LMQTDLTLMITGESGTGKELVARAL 180
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 200 bits (511), Expect = 9e-62 Identities = 101/339 (29%), Positives = 139/339 (41%), Gaps = 57/339 (16%) Query: 134 DPGLPQQWAMGTTTASL---NVRPAWDRTTGKGIVVAVIDTGI-TAHPDLAANVLPGYDF 189 + Q+ + + W++T G+G+ VAV+DTG HPDL A ++ G +F Sbjct: 10 YQVIKQEQQVNEIPRGVEMIQAPAVWNQTRGRGVKVAVLDTGCDADHPDLKARIIGGRNF 69 Query: 190 ITDPTVAGDGNGRDNNAADQGDWSAANACGAGASASNSSWHGTHVAGIVAAVGNNAAGVV 249 D G + + HGTHVAG +AA N GVV Sbjct: 70 TDDDE------------------------GDPEIFKDYNGHGTHVAGTIAATENEN-GVV 104 Query: 250 GTAFNAKLLPLRVLGKCG-GYMSDIADAIVWASGGKVTGVPANPNPATVINLSLGGYGSC 308 G A A LL ++VL K G G I I +A +I++SLGG Sbjct: 105 GVAPEADLLIIKVLNKQGSGQYDWIIQGIYYA----------IEQKVDIISMSLGGPEDV 154 Query: 309 STIIGNAITGAVTRGTAVVVAAGNSNMDVAT----SMPANCANVIAVAATTSAGAKASFS 364 + A+ AV V+ AAGN P VI+V A + FS Sbjct: 155 PEL-HEAVKKAVASQILVMCAAGNEGDGDDRTDELGYPGCYNEVISVGAINFDRHASEFS 213 Query: 365 NFGKGVDIAAPGQAIISTLNSGTTVPANPAYAVYSGTSMAAPHVAGVVALMQSVALN--- 421 N VD+ APG+ I+ST+ G YA +SGTSMA PHVAG +AL++ +A Sbjct: 214 NSNNEVDLVAPGEDILSTVPGGK-------YATFSGTSMATPHVAGALALIKQLANASFE 266 Query: 422 -PLTPATVEALLKSSARPLPVACAPGCGAGLVNADGAVA 459 LT + A L PL + G GL+ Sbjct: 267 RDLTEPELYAQLIKRTIPLGNS-PKMEGNGLLYLTAVEE 304
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 192 bits (490), Expect = 4e-61 Identities = 103/348 (29%), Positives = 139/348 (39%), Gaps = 58/348 (16%) Query: 2 EIDQIMYPTLTPNDTRLSEQWGFGTTASGINVRPAWDTATGTGVVVAVIDTGI-TSHPDL 60 ++ I Y + G I W+ G GV VAV+DTG HPDL Sbjct: 4 KVHIIPYQVIKQEQQVNEIPRGVEM----IQAPAVWNQTRGRGVKVAVLDTGCDADHPDL 59 Query: 61 NANVLPGYDFISDAARARDNNGRDSNAADQGDWRTANQCGTGVAAANSSWHGTHVAGTIA 120 A ++ G +F D++ D + HGTHVAGTIA Sbjct: 60 KARIIGGRNFT-------DDDEGDPEIFKDYNG-----------------HGTHVAGTIA 95 Query: 121 AVTNNSTGVAGTAFNARIVPIRALGLCG-GSSSDIADAIVWASGGTVSGVPANANPAEVI 179 A T N GV G A A ++ I+ L G G I I +A ++I Sbjct: 96 A-TENENGVVGVAPEADLLIIKVLNKQGSGQYDWIIQGIYYA----------IEQKVDII 144 Query: 180 NMSLGGNGTCSNTYQNAINGAVSRGTTVVVAAGNSNANVAN----FTPASCANVISVASI 235 +MSLGG A+ AV+ V+ AAGN P VISV +I Sbjct: 145 SMSLGGPED-VPELHEAVKKAVASQILVMCAAGNEGDGDDRTDELGYPGCYNEVISVGAI 203 Query: 236 TSAGARSSFSNFGTTIDISGPGSAILSTLNSGTTTPGSASYASYNGTSMAAPHVAGVVAL 295 S FSN +D+ PG ILST+ G YA+++GTSMA PHVAG +AL Sbjct: 204 NFDRHASEFSNSNNEVDLVAPGEDILSTVPGGK-------YATFSGTSMATPHVAGALAL 256 Query: 296 VQSAAS----RPLTPAAVETLLKNTARPLPGACSGGCGAGIVNAAGAV 339 ++ A+ R LT + L PL + G G++ Sbjct: 257 IKQLANASFERDLTEPELYAQLIKRTIPLGNS-PKMEGNGLLYLTAVE 303
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 194 bits (494), Expect = 4e-59 Identities = 99/335 (29%), Positives = 141/335 (42%), Gaps = 57/335 (17%) Query: 147 QWAFGTTNAGL---NIRPAWDKATGSGTVVAVIDTGI-TSHADLNANILAGYDFISDATT 202 + G+ W++ G G VAV+DTG H DL A I+ G +F D Sbjct: 16 EQQVNEIPRGVEMIQAPAVWNQTRGRGVKVAVLDTGCDADHPDLKARIIGGRNFTDD--- 72 Query: 203 ARDGNGRDSNAADEGDWYAANECGAGIPAASSSWHGTHVAGTVAAVTNNTTGVAGTAYGA 262 DEGD + HGTHVAGT+AA T N GV G A A Sbjct: 73 ------------DEGDPE---------IFKDYNGHGTHVAGTIAA-TENENGVVGVAPEA 110 Query: 263 KVVPVRVLGKCG-GSLSDIADAIVWASGGTVSGIPANANPAEVINMSLGGGGSCSTTMQN 321 ++ ++VL K G G I I +A ++I+MSLGG + Sbjct: 111 DLLIIKVLNKQGSGQYDWIIQGIYYA----------IEQKVDIISMSLGGPED-VPELHE 159 Query: 322 AINGAVSRGTTVVVAAGNDASNVSG----SLPANCANVIAVAATTSAGAKASYSNFGTGI 377 A+ AV+ V+ AAGN+ P VI+V A + +SN + Sbjct: 160 AVKKAVASQILVMCAAGNEGDGDDRTDELGYPGCYNEVISVGAINFDRHASEFSNSNNEV 219 Query: 378 DVSAPGSSILSTLNSGTTTPGSASYASYNGTSMASPHVAGVVALVQSVAPTA----LTPA 433 D+ APG ILST+ G YA+++GTSMA+PHVAG +AL++ +A + LT Sbjct: 220 DLVAPGEDILSTVPGGK-------YATFSGTSMATPHVAGALALIKQLANASFERDLTEP 272 Query: 434 AVETLLKNTARALPGACSGGCGAGIVNADAAVTAA 468 + L L + G G++ A + Sbjct: 273 ELYAQLIKRTIPLGNS-PKMEGNGLLYLTAVEELS 306
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 47.7 bits (113), Expect = 5e-09 Identities = 19/120 (15%), Positives = 41/120 (34%), Gaps = 3/120 (2%) Query: 37 AALRRAAWEIVAESGARALTLRACARRAGVSHAAPAHHFGSLNGLVAEMVADGYERMVAR 96 + A + ++ G + +L A+ AGV+ A HF + L +E+ + Sbjct: 14 QHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGEL 73 Query: 97 IAATQQDVSD---PVMGCGLGYIRFAIEFPQHFRLMLSLDLRAHPLPRLAQASEAARACL 153 Q V+ L ++ + + RL++ + + A+ L Sbjct: 74 ELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRNL 133
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 408 bits (1050), Expect = e-135 Identities = 175/703 (24%), Positives = 298/703 (42%), Gaps = 115/703 (16%) Query: 65 VIRRGSGTMINQSAAAAPSPTLGMASSGSATFNFEGESVQAVVKAILGDMLGQNYVIAPG 124 VIR S T++ +A A++ + +F+G +Q + + + L + +I P Sbjct: 6 VIRSFSLTLLIFAALLFRP-----AAAEEFSASFKGTDIQEFINTVSKN-LNKTVIIDPS 59 Query: 125 VQGTVTLATPNPVSPAQALNLLEMVLG-WNNARMVFSGGRYNIVPA-DQALAGTVAPSTA 182 V+GT+T+ + + ++ Q VL + A + + G +V + D A S A Sbjct: 60 VRGTITVRSYDMLNEEQYYQFFLSVLDVYGFAVINMNNGVLKVVRSKDAKTAAVPVASDA 119 Query: 183 SPSAARGFEVRVVPLKYISASEMKKVLEPYARPNAIVGTDA---SRNVITLGGTRAELEN 239 +P RVVPL ++A ++ +L NA VG+ NV+ + G A ++ Sbjct: 120 APGIGDEVVTRVVPLTNVAARDLAPLLRQL-NDNAGVGSVVHYEPSNVLLMTGRAAVIKR 178 Query: 240 YLRTVQIFDVDWLSGMSVGVFPIQSGKAEKISADLEKVFGEQSKT--PSAGMFRFMPLEN 297 L V+ VD SV P+ A + + ++ + SK+ P + + + E Sbjct: 179 LLTIVE--RVDNAGDRSVVTVPLSWASAADVVKLVTELNKDTSKSALPGSMVANVVADER 236 Query: 298 ANAVLVI---TPQPRYLDQIQQWLDRIDSAGGGVRLFSYELKYIKAKDLADRLSEVFGGR 354 NAVLV + R + I+Q LDR + G ++ LKY KA DL + L+ + Sbjct: 237 TNAVLVSGEPNSRQRIIAMIKQ-LDRQQATQGNTKVIY--LKYAKASDLVEVLTGI---- 289 Query: 355 GNGGNSGPSLVPGGVVNMLGNNSGGADRDESLGSSSGATGGDIGGTSNGSSQSGTSGSFG 414 +S S+ + Sbjct: 290 ---------------------------------------------SSTMQSEKQAAKPVA 304 Query: 415 GSSGSGMLQLPPSTNQNGSVTLEVEGDKVGVSAVAETNTLLVRTSAQAWKSIRDVIEKLD 474 + +++ TN L V ++ + VI +LD Sbjct: 305 ALDKNIIIKAHGQTN-----ALIVTAAPDVMNDLER------------------VIAQLD 341 Query: 475 VMPMQVHIEAQIAEVTLTGRLQYGVNWYFENAVTTPSNADGSGGPNLPSAAGRGIW---G 531 + QV +EA IAEV L G+ W +NA T SG P + AG + G Sbjct: 342 IRRPQVLVEAIIAEVQDADGLNLGIQWANKNAGMT--QFTNSGLPISTAIAGANQYNKDG 399 Query: 532 DVSGSVTS-----NGVAWTFLGKNAAAIISALDQVTNLRLLQTPSVFVRNNAEATLNVGS 586 VS S+ S NG+A F N A +++AL T +L TPS+ +N EAT NVG Sbjct: 400 TVSSSLASALSSFNGIAAGFYQGNWAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQ 459 Query: 587 RIPINSTSINTGLGSDSSFSSVQYIDTGVILKVRPRVTKDGMVFLDIVQEVSTPGARPAA 646 +P+ + S T D+ F++V+ G+ LKV+P++ + V L+I QEVS+ Sbjct: 460 EVPVLTGSQTT--SGDNIFNTVERKTVGIKLKVKPQINEGDSVLLEIEQEVSSV------ 511 Query: 647 CTAAATTTVNSAACNVDINTRRVKTEAAVQNGDTIMLAGLIDDSTTDGSNGIPFLSKLPV 706 A + S+ NTR V V +G+T+++ GL+D S +D ++ +P L +PV Sbjct: 512 ---ADAASSTSSDLGATFNTRTVNNAVLVGSGETVVVGGLLDKSVSDTADKVPLLGDIPV 568 Query: 707 VGALFGRKTQNSDRREVIVLITPSIVRNPQDARDLTDEYGSKF 749 +GALF ++ +R +++ I P+++R+ + R + + F Sbjct: 569 IGALFRSTSKKVSKRNLMLFIRPTVIRDRDEYRQASSGQYTAF 611
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 33.8 bits (77), Expect = 5e-04 Identities = 20/84 (23%), Positives = 27/84 (32%), Gaps = 7/84 (8%) Query: 145 IEGPGGTQTLELQVFNGQGGQPPTAIGGRPQAPGAVPPLPPNVPPAPATPAPPPAEVPQQ 204 IE P Q + + + +PP QA P P P PP E P Sbjct: 36 IELPAPAQPISVTMVTPADLEPP-------QAVQPPPEPVVEPEPEPEPIPEPPKEAPVV 88 Query: 205 QPGGQAPPTVPPQRSDGAQEAPRP 228 + P P+ QE P+ Sbjct: 89 IEKPKPKPKPKPKPVKKVQEQPKR 112
>PilS_PF08805#PilS N terminal Length = 185 Score = 34.1 bits (78), Expect = 9e-05 Identities = 7/55 (12%), Positives = 22/55 (40%), Gaps = 4/55 (7%) Query: 1 MKHQRGYSLIEVIVAFALLALALTLLLGSLSGAARQVRGADDSTRATLHAQSLLA 55 + +G +L+EV++ ++ + S + S+ + +++A Sbjct: 22 KEQDKGATLMEVLLVVGVIVVLAASAYKLYSMV----QSNIQSSNEQNNVLTVIA 72
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 30.7 bits (69), Expect = 0.002 Identities = 24/108 (22%), Positives = 49/108 (45%), Gaps = 1/108 (0%) Query: 21 QLRGSSLLEMLLVIALIALAGVLAAAALTGGIDGMRLRSAGKAIAAQLRYTRTQAIATGT 80 + RG +LLEM+L++ L+ ++ + A D ++ + AQLR+ + + + TG Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQTLAR-FEAQLRFVQQRGLQTGQ 60 Query: 81 PQRFLIDPQQRRWEAPGGHHGDLPAALEVRFTGARQVQSRQDQGAIQF 128 + P + ++ G PA + ++G R + R + A Sbjct: 61 FFGVSVHPDRWQFLVLEARDGADPAPADDGWSGYRWLPLRAGRVATSG 108
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 141 bits (358), Expect = 2e-46 Identities = 41/132 (31%), Positives = 61/132 (46%), Gaps = 18/132 (13%) Query: 15 QAGMSLLEIIIVIVLIGAVLTLVGSRVLGGADRGKANLAKSQIQTLAGKIENFQLDTGKL 74 Q G +LLEI++VIV+IG + +LV ++G ++ A S I L ++ ++LD Sbjct: 7 QRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDNHHY 66 Query: 75 PSKLDDLVTQPGGSSGWLGPYAKPVELN------------DPWGHTIEYRVPGDGQAFDL 122 P+ T G S P P+ N DPWG+ PG+ A+DL Sbjct: 67 PT------TNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDL 120 Query: 123 ISLGKDGRPGGS 134 +S G DG G Sbjct: 121 LSAGPDGEMGTE 132
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 436 bits (1122), Expect = e-154 Identities = 135/411 (32%), Positives = 215/411 (52%), Gaps = 12/411 (2%) Query: 1 MPLYRYKALDAHGEMLDGQMEAANDAEVALRLQEQGHLPV---ETRLATGENGSPSLRML 57 M Y Y+ALDA G+ G EA + + L+E+G +P+ E R ++GS L L Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLS-L 59 Query: 58 LRKKPFDNAALVQFTQQLATLIGAGQPLDRALSILMDLPEDDKSRRVIADIRDTVRGGAP 117 RK + L T+QLATL+ A PL+ AL + E +++A +R V G Sbjct: 60 RRKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHS 119 Query: 118 LSVALERQHGLFSKLYINMVRAGEAGGSMQDTLQRLADYLERSRALKGKVINALIYPAIL 177 L+ A++ G F +LY MV AGE G + L RLADY E+ + ++ ++ A+IYP +L Sbjct: 120 LADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVL 179 Query: 178 LAVVGCALLFLLGYVVPQFAQMYESLDVALPWFTQAVLSVGLLVRDW--WLVLVVIPGVL 235 V + LL VVP+ + + + ALP T+ ++ + VR + W++L ++ G + Sbjct: 180 TVVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFM 239 Query: 236 G--LWLDRKRRNAAFRAALDAWLLRQKVIGSLIARLETARLTRTLGTLLRNGVPLLAAIG 293 + L +++R R + LL +IG + L TAR RTL L + VPLL A+ Sbjct: 240 AFRVMLRQEKR----RVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMR 295 Query: 294 IARNVMSNTALVEDVAAAADDVKNGHGLSMSLARGKRFPRLALQMIQVGEESGALDTMLL 353 I+ +VMSN ++ A D V+ G L +L + FP + MI GE SG LD+ML Sbjct: 296 ISGDVMSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLE 355 Query: 354 KTADTFELETAQAIDRALAALVPLITLVLASVVGLVIISVLVPLYDLTNAI 404 + AD + E + + AL PL+ + +A+VV +++++L P+ L + Sbjct: 356 RAADNQDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 204 bits (521), Expect = 1e-62 Identities = 103/362 (28%), Positives = 152/362 (41%), Gaps = 68/362 (18%) Query: 156 PQLVPNDPLYAQYQWHLSNPNGGINAPAAWDLSQGAGVVVAVLDTGILPGHPDFAGNLLQ 215 Q++ + + + I APA W+ ++G GV VAVLDTG HPD ++ Sbjct: 10 YQVIKQEQQVNEIPRGV----EMIQAPAVWNQTRGRGVKVAVLDTGCDADHPDLKARIIG 65 Query: 216 GYDFITDAEVSRRPTDARVPGALDYGDWEEADNVCYDGSVAQESSWHGTHVSGTVAEATH 275 G +F D+ D + ++ + HGTHV+GT+A AT Sbjct: 66 GRNF--------------------------TDDDEGDPEIFKDYNGHGTHVAGTIA-ATE 98 Query: 276 NGVGMAGVAPKATILPVRVLGRCG-GYTSDIADAIVWASGGTVDGVPANTNPAEVINMSL 334 N G+ GVAP+A +L ++VL + G G I I +A VD +I+MSL Sbjct: 99 NENGVVGVAPEADLLIIKVLNKQGSGQYDWIIQGIYYAIEQKVD----------IISMSL 148 Query: 335 GGGEPCDPATQVAINGAVSRGTTVVVAAGNSGEDAAN----HSPASCNNTITVGATRITG 390 GG E A+ AV+ V+ AAGN G+ P N I+VGA Sbjct: 149 GGPEDVP-ELHEAVKKAVASQILVMCAAGNEGDGDDRTDELGYPGCYNEVISVGAINFDR 207 Query: 391 GIIYYSNYGSQVDLSGPGGGSVDGNPGGYIWQAGYDGATTPTSGSYSYMGIGGTSMASPH 450 +SN ++VDL PG I G Y GTSMA+PH Sbjct: 208 HASEFSNSNNEVDLVAPGED---------ILSTVPGG---------KYATFSGTSMATPH 249 Query: 451 VAGVVALVQSASIGLGDGPLTPAAMEALLKQTSRRFPVTPPTSTPIGSGIVDAKAALEAV 510 VAG +AL++ + + LT + A L + + +P G+G++ A E Sbjct: 250 VAGALALIKQLANASFERDLTEPELYAQLIKRTIPLGNSPKME---GNGLLYLTAVEELS 306 Query: 511 LV 512 + Sbjct: 307 RI 308
>OMADHESIN#Yersinia outer membrane adhesin signature. Length = 455 Score = 55.7 bits (133), Expect = 2e-09 Identities = 71/241 (29%), Positives = 108/241 (44%), Gaps = 24/241 (9%) Query: 1270 GAESVADGTSAAAFGFGAEATSNYSTALGGYSTASGFNSTALGNFSTASGSSSVAVGGDA 1329 G + A G + A G AEA + A+G S A+G NS A+G S A G S+V G + Sbjct: 62 GLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGAAS 121 Query: 1330 TASGAYSIAAGQASVASGYNSVAVGGALLGLLPTEASGDFSTALGGAAWAPGLNSTALGN 1389 TA + VA+G ++ D A+G + A NS A+G+ Sbjct: 122 TAQK---------------DGVAIGA-------RASTSDTGVAVGFNSKADAKNSVAIGH 159 Query: 1390 FAESTGES--SVALGADSVADRDFAVSVGSAGNERQITNVAAGTQGTDAVNLDQLTAVAE 1447 + S+A+G S DR+ +VS+G RQ+T++AAGT+ TDAVN+ QL E Sbjct: 160 SSHVAANHGYSIAIGDRSKTDRENSVSIGHESLNRQLTHLAAGTKDTDAVNVAQLKKEIE 219 Query: 1448 TAQGTSKYFKASGSDDSDAGAYIEGDNALAAGEGANASSDNSTAVGAGAQAVAENATAVG 1507 Q + A +++A A + + L S T A +A A++ + Sbjct: 220 KTQENTNKRSAELLANANAYADNKSSSVLGIANNYTDSKSAETLENARKEAFAQSKDVLN 279 Query: 1508 M 1508 M Sbjct: 280 M 280 Score = 55.7 bits (133), Expect = 2e-09 Identities = 65/193 (33%), Positives = 94/193 (48%), Gaps = 22/193 (11%) Query: 72 GRGASAPAAHATAIGAGSNASATGAVATGADSSASGVNSSAIGRQTNAIGENAVAIGYNS 131 G ASA H+ AIGA + A+ AVA GA S A+GVNS AIG + A+G++AV G S Sbjct: 62 GLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGAAS 121 Query: 132 FVRQAG----------ENGVALGANAGVTGANSVALGAGSRTHEDDVVSVGSGNGRGG-- 179 ++ G + GVA+G N+ NSVA+G S + S+ G+ Sbjct: 122 TAQKDGVAIGARASTSDTGVAVGFNSKADAKNSVAIGHSSHVAANHGYSIAIGDRSKTDR 181 Query: 180 ---------PATRRITNVSAGVNANDAVNVAQLQAVSEVAEDTATFFKAQPGDDSIGAYA 230 R++T+++AG DAVNVAQL+ E ++ A+ ++ AYA Sbjct: 182 ENSVSIGHESLNRQLTHLAAGTKDTDAVNVAQLKKEIEKTQENTNKRSAELLANA-NAYA 240 Query: 231 DGAGAVAAGDAAN 243 D + G A N Sbjct: 241 DNKSSSVLGIANN 253 Score = 50.3 bits (119), Expect = 8e-08 Identities = 54/164 (32%), Positives = 81/164 (49%), Gaps = 5/164 (3%) Query: 2104 AATSTAVGNAAVANHITGTAIGGSAYAHGPNDTAIGSNARVNADGSTAVGANTQIAAVAT 2163 AT+ A AAVA A G ++ A GP A+G +A STA I A A+ Sbjct: 76 GATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGAASTAQKDGVAIGARAS 135 Query: 2164 NA---VAMGEGAQVSAASGTAIGQGARASAQG--AVALGQGSVADRANTVSVGSVGGERQ 2218 + VA+G ++ A + AIG + +A ++A+G S DR N+VS+G RQ Sbjct: 136 TSDTGVAVGFNSKADAKNSVAIGHSSHVAANHGYSIAIGDRSKTDRENSVSIGHESLNRQ 195 Query: 2219 VANVAAGTRATDAVNKGQLDSGVAAANSYTDSRYSAMADSFETY 2262 + ++AAGT+ TDAVN QL + T+ R + + + Y Sbjct: 196 LTHLAAGTKDTDAVNVAQLKKEIEKTQENTNKRSAELLANANAY 239 Score = 49.5 bits (117), Expect = 1e-07 Identities = 51/144 (35%), Positives = 72/144 (50%), Gaps = 3/144 (2%) Query: 834 GANAYAADTGSIAVGTYANAYGPRAISLGGQSNAAGDESIALGWEAQAEGDQGIALGAGS 893 G NA A SIA+G A A A+++G S A G S+A+G ++A GD + GA S Sbjct: 62 GLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGAAS 121 Query: 894 QADAYSTAIGGYATASGASATAVGNNSRAVDGYATALGSDSMASGN--FSTTVGGASVAS 951 A AIG A+ S + AVG NS+A + A+G S + N +S +G S Sbjct: 122 TAQKDGVAIGARASTSD-TGVAVGFNSKADAKNSVAIGHSSHVAANHGYSIAIGDRSKTD 180 Query: 952 GRGATAIGAESVARMDRDTAIGTE 975 + +IG ES+ R A GT+ Sbjct: 181 RENSVSIGHESLNRQLTHLAAGTK 204 Score = 49.5 bits (117), Expect = 1e-07 Identities = 59/165 (35%), Positives = 82/165 (49%), Gaps = 26/165 (15%) Query: 371 GTQTSASGTSSTAVGGPVDLIPGLGFFVQTQASGEAASALGAGAIASGTYTTAVGTLSEA 430 G SA G S A+G +A+ AA A+GAG+IA+G + A+G LS+A Sbjct: 62 GLNASAKGIHSIAIGA------------TAEAAKGAAVAVGAGSIATGVNSVAIGPLSKA 109 Query: 431 SGTEATAVGYFAYAPGEG------------ATAVGPESWASGELSTALGYYS--TARGAN 476 G A G + A +G AVG S A + S A+G+ S A Sbjct: 110 LGDSAVTYGAASTAQKDGVAIGARASTSDTGVAVGFNSKADAKNSVAIGHSSHVAANHGY 169 Query: 477 SVALGANSVATRADTVSVGAAGAERQITSVAAGTEGTDAVNLNQL 521 S+A+G S R ++VS+G RQ+T +AAGT+ TDAVN+ QL Sbjct: 170 SIAIGDRSKTDRENSVSIGHESLNRQLTHLAAGTKDTDAVNVAQL 214 Score = 46.8 bits (110), Expect = 9e-07 Identities = 56/159 (35%), Positives = 79/159 (49%), Gaps = 4/159 (2%) Query: 650 ALGVGSVAFGGTSTAVGGASVAFGTDSAAFGANAAAGGTASTAIGANSNAFGERTVALGG 709 ALG+ A G + A G S A GA A A A+ A+GA S A G +VA+G Sbjct: 46 ALGLEYPVRPPVPGAGGLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGP 105 Query: 710 ASNASGDESIALGVSSLASALGTTAVGSNANASIANATAVGFNSSAGDDYATALGGDSN- 768 S A GD ++ G +S A G A+G+ A+ S AVGFNS A + A+G S+ Sbjct: 106 LSKALGDSAVTYGAASTAQKDG-VAIGARASTS-DTGVAVGFNSKADAKNSVAIGHSSHV 163 Query: 769 -ASGYFSTAVGGTSIANGRGATAIGYESIGNGAASTALG 806 A+ +S A+G S + + +IG+ES+ A G Sbjct: 164 AANHGYSIAIGDRSKTDRENSVSIGHESLNRQLTHLAAG 202 Score = 45.3 bits (106), Expect = 2e-06 Identities = 64/211 (30%), Positives = 95/211 (45%), Gaps = 60/211 (28%) Query: 903 GGYATASGASATAVGNNSRAVDGYATALGSDSMASGNFSTTVGGASVASGRGATAIGAES 962 G A+A G + A+G + A G A A+G+ S+A+G S +G S A G A GA S Sbjct: 62 GLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGAAS 121 Query: 963 VARMDRDTAIGTESVADGGDSTALGANARASYDSSVALGANANSSNYYSVALGTYAVATG 1022 A+ D VA+GA A++S Sbjct: 122 TAQKD-----------------------------GVAIGARASTS--------------- 137 Query: 1023 GSATSIGGQSYAPGNESVALGWQSNASGTRSVSLGSGAYTPADDG--VALGAGSIADRDN 1080 + VA+G+ S A SV++G ++ A+ G +A+G S DR+N Sbjct: 138 --------------DTGVAVGFNSKADAKNSVAIGHSSHVAANHGYSIAIGDRSKTDREN 183 Query: 1081 TVSVGSVGSERQITNVAAGTEGTDAVNLDQL 1111 +VS+G RQ+T++AAGT+ TDAVN+ QL Sbjct: 184 SVSIGHESLNRQLTHLAAGTKDTDAVNVAQL 214 Score = 44.9 bits (105), Expect = 3e-06 Identities = 58/199 (29%), Positives = 94/199 (47%), Gaps = 8/199 (4%) Query: 820 GTESVAYGDDSTALGANAYAADTGSIAVGTYANAYGPRAISLGGQSNAAGDESIALGWEA 879 G + A G S A+GA A AA ++AVG + A G ++++G S A GD ++ G + Sbjct: 62 GLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGAAS 121 Query: 880 QAEGDQGIALGAGSQADAYSTAIGGYATASGASATAVGNNSR--AVDGYATALGSDSMAS 937 A+ D G+A+GA + A+G + A ++ A+G++S A GY+ A+G S Sbjct: 122 TAQKD-GVAIGARASTSDTGVAVGFNSKADAKNSVAIGHSSHVAANHGYSIAIGDRSKTD 180 Query: 938 GNFSTTVGGASVASGRGATAIG-----AESVARMDRDTAIGTESVADGGDSTALGANARA 992 S ++G S+ A G A +VA++ ++ E+ ANA A Sbjct: 181 RENSVSIGHESLNRQLTHLAAGTKDTDAVNVAQLKKEIEKTQENTNKRSAELLANANAYA 240 Query: 993 SYDSSVALGANANSSNYYS 1011 SS LG N ++ S Sbjct: 241 DNKSSSVLGIANNYTDSKS 259 Score = 44.5 bits (104), Expect = 4e-06 Identities = 54/159 (33%), Positives = 80/159 (50%), Gaps = 4/159 (2%) Query: 1170 AIGSGASATAQYANASGYNAAASGYGSVSTGAFSQASGDYGVALGGESEASGAQSTAVGA 1229 A+G A G NA+A G S++ GA ++A+ VA+G S A+G S A+G Sbjct: 46 ALGLEYPVRPPVPGAGGLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGP 105 Query: 1230 AAGASGDGAFAGGALSVAEGTESTALGYFASATGESATAVGAESVADGTSAAAFGFGAEA 1289 + A GD A GA S A+ + A+G AS T ++ AVG S AD ++ A G + Sbjct: 106 LSKALGDSAVTYGAASTAQ-KDGVAIGARAS-TSDTGVAVGFNSKADAKNSVAIGHSSHV 163 Query: 1290 TSN--YSTALGGYSTASGFNSTALGNFSTASGSSSVAVG 1326 +N YS A+G S NS ++G+ S + +A G Sbjct: 164 AANHGYSIAIGDRSKTDRENSVSIGHESLNRQLTHLAAG 202 Score = 42.6 bits (99), Expect = 2e-05 Identities = 44/132 (33%), Positives = 70/132 (53%), Gaps = 4/132 (3%) Query: 764 GGDSNASGYFSTAVGGTSIANGRGATAIGYESIGNGAASTALGFASVAWGEGGTAIGTES 823 G +++A G S A+G T+ A A A+G SI G S A+G S A G+ G S Sbjct: 62 GLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGAAS 121 Query: 824 VAYGDDSTALGANAYAADTGSIAVGTYANAYGPRAISLGGQSNAAGDE--SIALGWEAQA 881 A D A+GA A +DTG +AVG + A ++++G S+ A + SIA+G ++ Sbjct: 122 TAQ-KDGVAIGARASTSDTG-VAVGFNSKADAKNSVAIGHSSHVAANHGYSIAIGDRSKT 179 Query: 882 EGDQGIALGAGS 893 + + +++G S Sbjct: 180 DRENSVSIGHES 191 Score = 42.6 bits (99), Expect = 2e-05 Identities = 57/210 (27%), Positives = 89/210 (42%), Gaps = 21/210 (10%) Query: 1653 GFIPARASGTGAAAFGGGAWATADYTTAIGWNSYADGVNASALGQSAAALADNALAIGGN 1712 G + A A G + A G A A A+G S A GVN+ A+G + AL D+A+ G Sbjct: 61 GGLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGAA 120 Query: 1713 SRADAIGASVVGVDASATGINSTGVGRQVNVIGENAVSVGYNSFVRESAVNGVALGANAG 1772 S A G + +G AS + + V+VG+NS + ++ Sbjct: 121 STAQKDGVA-IGARASTS---------------DTGVAVGFNSKADAKNSVAIGHSSHVA 164 Query: 1773 ATGADSVALGSGSRTYEANTVSVGSGNGRGGPATRRIVNVSDGEVATDAVNKGQLDALAA 1832 A S+A+G S+T N+VS+G + R++ +++ G TDAVN QL Sbjct: 165 ANHGYSIAIGDRSKTDRENSVSIGHES-----LNRQLTHLAAGTKDTDAVNVAQLKKEIE 219 Query: 1833 DVQTTSGMVQTTGEGVARATGDRATAAGAG 1862 Q + A A D +++ G Sbjct: 220 KTQENTNKRSAELLANANAYADNKSSSVLG 249 Score = 40.3 bits (93), Expect = 9e-05 Identities = 38/103 (36%), Positives = 58/103 (56%), Gaps = 4/103 (3%) Query: 1858 AAGAGATASGARSVAVAAGSTASATGASAMGVDSSASGVNSTAMGRQTNSIGENGVALGY 1917 A G A+A G S+A+ A + A+ A A+G S A+GVNS A+G + ++G++ V G Sbjct: 60 AGGLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGA 119 Query: 1918 NSFVRQSGANAVALGANAGASGADSVALGSGSRTYEANVVSVG 1960 S ++ G VA+GA A S VA+G S+ N V++G Sbjct: 120 ASTAQKDG---VAIGARASTSDT-GVAVGFNSKADAKNSVAIG 158 Score = 40.3 bits (93), Expect = 9e-05 Identities = 45/131 (34%), Positives = 70/131 (53%), Gaps = 4/131 (3%) Query: 552 AAGSNAAAFNDYSTALGSSSVASAQGATAVGSGANATTDNATAVGFNSTAVAENTTALGG 611 A G NA+A +S A+G+++ A+ A AVG+G+ AT N+ A+G S A+ ++ G Sbjct: 60 AGGLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGA 119 Query: 612 NSSASGDGSTAVGGATRATASGATALGYESIANGADSTALGVGS--VAFGGTSTAVGGAS 669 S+A DG GA +T+ A+G+ S A+ +S A+G S A G S A+G S Sbjct: 120 ASTAQKDGVAI--GARASTSDTGVAVGFNSKADAKNSVAIGHSSHVAANHGYSIAIGDRS 177 Query: 670 VAFGTDSAAFG 680 +S + G Sbjct: 178 KTDRENSVSIG 188 Score = 39.5 bits (91), Expect = 2e-04 Identities = 42/123 (34%), Positives = 61/123 (49%), Gaps = 12/123 (9%) Query: 610 GGNSSASGDGSTAVGGATRATASGATALGYESIANGADSTALGVGSVAFGGTSTAVGGAS 669 G N+SA G S A+G A A A+G A S A GV SVA G S A+G ++ Sbjct: 62 GLNASAKGIHSIAIGATAEAAKGAAVAVG-------AGSIATGVNSVAIGPLSKALGDSA 114 Query: 670 VAFGTDSAAFGANAAAGGTAST-----AIGANSNAFGERTVALGGASNASGDESIALGVS 724 V +G S A A G AST A+G NS A + +VA+G +S+ + + ++ + Sbjct: 115 VTYGAASTAQKDGVAIGARASTSDTGVAVGFNSKADAKNSVAIGHSSHVAANHGYSIAIG 174 Query: 725 SLA 727 + Sbjct: 175 DRS 177 Score = 38.0 bits (87), Expect = 5e-04 Identities = 37/130 (28%), Positives = 67/130 (51%) Query: 1477 AAGEGANASSDNSTAVGAGAQAVAENATAVGMDALASGIGAAALGNNAQALGENSSAVGS 1536 A G A+A +S A+GA A+A A AVG ++A+G+ + A+G ++ALG+++ G+ Sbjct: 60 AGGLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGA 119 Query: 1537 NALASDIGATANGAGAQAISTYATALGSEAVASDNQATAVGFRSAASNVGSAAFGGYSES 1596 + A G + + + A S+A A ++ A AA++ S A G S++ Sbjct: 120 ASTAQKDGVAIGARASTSDTGVAVGFNSKADAKNSVAIGHSSHVAANHGYSIAIGDRSKT 179 Query: 1597 SGRLSSALGY 1606 S ++G+ Sbjct: 180 DRENSVSIGH 189 Score = 37.2 bits (85), Expect = 8e-04 Identities = 38/141 (26%), Positives = 67/141 (47%) Query: 1200 GAFSQASGDYGVALGGESEASGAQSTAVGAAAGASGDGAFAGGALSVAEGTESTALGYFA 1259 G + A G + +A+G +EA+ + AVGA + A+G + A G LS A G + G + Sbjct: 62 GLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGAAS 121 Query: 1260 SATGESATAVGAESVADGTSAAAFGFGAEATSNYSTALGGYSTASGFNSTALGNFSTASG 1319 +A + S +D A F A+A ++ + + A+ S A+G+ S Sbjct: 122 TAQKDGVAIGARASTSDTGVAVGFNSKADAKNSVAIGHSSHVAANHGYSIAIGDRSKTDR 181 Query: 1320 SSSVAVGGDATASGAYSIAAG 1340 +SV++G ++ +AAG Sbjct: 182 ENSVSIGHESLNRQLTHLAAG 202 Score = 35.6 bits (81), Expect = 0.002 Identities = 59/189 (31%), Positives = 85/189 (44%), Gaps = 25/189 (13%) Query: 1538 ALASDIGATANGAGAQAISTYATALGSEAVASDNQATAVGFRSAASNVGSAAFGGYSESS 1597 A A D N Q ALG E A G ++A + S A G +E++ Sbjct: 23 AFADDYDGIPNLTAVQISPNADPALGLEYPVRPPVPGAGGLNASAKGIHSIAIGATAEAA 82 Query: 1598 GRLSSALGYGAVASSDYSTAVGAASLASGASAVAVGEFSEATGDESVAVGGSTFFGFIPA 1657 + A+G G++A+ S A+G S A G SAV G S A D VA+G A Sbjct: 83 KGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGAASTAQKD-GVAIG---------A 132 Query: 1658 RASGTGAAAFGGGAWATADYTTAIGWNSYADGVNASALGQSAAALADN--ALAIGGNSRA 1715 RAS T+D A+G+NS AD N+ A+G S+ A++ ++AIG S+ Sbjct: 133 RAS-------------TSDTGVAVGFNSKADAKNSVAIGHSSHVAANHGYSIAIGDRSKT 179 Query: 1716 DAIGASVVG 1724 D + +G Sbjct: 180 DRENSVSIG 188 Score = 35.6 bits (81), Expect = 0.003 Identities = 47/142 (33%), Positives = 71/142 (50%), Gaps = 4/142 (2%) Query: 1135 AQGEDATAAGSNATADADYSSAFGASSQATAIGAVAIGSGASATAQYANASGYNAAASGY 1194 + A G NA+A +S A GA+++A AVA+G+G+ AT + A G + A G Sbjct: 53 VRPPVPGAGGLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGD 112 Query: 1195 GSVSTGAFSQASGDYGVALGGESEASGAQSTAVGAAAGASGDGAFAGGALS--VAEGTES 1252 +V+ GA S A D GVA+G + S AVG + A + A G S A S Sbjct: 113 SAVTYGAASTAQKD-GVAIGARASTSDT-GVAVGFNSKADAKNSVAIGHSSHVAANHGYS 170 Query: 1253 TALGYFASATGESATAVGAESV 1274 A+G + E++ ++G ES+ Sbjct: 171 IAIGDRSKTDRENSVSIGHESL 192 Score = 34.9 bits (79), Expect = 0.004 Identities = 45/147 (30%), Positives = 73/147 (49%), Gaps = 4/147 (2%) Query: 1518 AALGNNAQALGENSSAVGSNALASDIGATANGAGAQAISTYATALGSEAVASDNQATAVG 1577 A G NA A G +S A+G+ A A+ A A GAG+ A + A+G + A + A G Sbjct: 59 GAGGLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYG 118 Query: 1578 FRSAASNVGSAAFGGYSESSGRLSSALGYGAVASSDYSTAVGAAS--LASGASAVAVGEF 1635 S A G A G S+ A+G+ + A + S A+G +S A+ ++A+G+ Sbjct: 119 AASTAQKDGVAI--GARASTSDTGVAVGFNSKADAKNSVAIGHSSHVAANHGYSIAIGDR 176 Query: 1636 SEATGDESVAVGGSTFFGFIPARASGT 1662 S+ + SV++G + + A+GT Sbjct: 177 SKTDRENSVSIGHESLNRQLTHLAAGT 203 Score = 34.1 bits (77), Expect = 0.007 Identities = 43/137 (31%), Positives = 57/137 (41%), Gaps = 1/137 (0%) Query: 393 GLGFFVQTQASGEAASALGAGAIASGTYTTAVGTLSEASGTEATAVGYFAYAPGEGATAV 452 G+ Q S A ALG A G + A G + A+G A A A AV Sbjct: 30 GIPNLTAVQISPNADPALGLEYPVRPPVPGAGGLNASAKGIHSIAIGATAEAAKGAAVAV 89 Query: 453 GPESWASGELSTALGYYSTARGANSVALGANSVATRADTVSVGAAGAERQITSVAAGTEG 512 G S A+G S A+G S A G ++V GA S A + D V++GA + Sbjct: 90 GAGSIATGVNSVAIGPLSKALGDSAVTYGAASTAQK-DGVAIGARASTSDTGVAVGFNSK 148 Query: 513 TDAVNLNQLTAVSDVAS 529 DA N + S VA+ Sbjct: 149 ADAKNSVAIGHSSHVAA 165 Score = 33.7 bits (76), Expect = 0.010 Identities = 38/114 (33%), Positives = 57/114 (50%), Gaps = 2/114 (1%) Query: 1127 GTGDGTAFAQGEDATAAGSNATADADYSSAFGASSQATAIGAVAIGSGASATAQYANASG 1186 G G A A+G + A G+ A A + A GA S AT + +VAIG + A A G Sbjct: 59 GAGGLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYG 118 Query: 1187 YNAAASGYGSVSTGAFSQASGDYGVALGGESEASGAQSTAVGAAAGASGDGAFA 1240 + A G V+ GA + S D GVA+G S+A S A+G ++ + + ++ Sbjct: 119 AASTAQKDG-VAIGARASTS-DTGVAVGFNSKADAKNSVAIGHSSHVAANHGYS 170 Score = 33.3 bits (75), Expect = 0.013 Identities = 38/130 (29%), Positives = 61/130 (46%), Gaps = 3/130 (2%) Query: 1043 GWQSNASGTRSVSLGSGAYTPADDGVALGAGSIADRDNTVSVGSVGSERQITNVAAGTEG 1102 G ++A G S+++G+ A VA+GAGSIA N+V++G + + V G Sbjct: 62 GLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGAAS 121 Query: 1103 TDAVNLDQLNAVAGTAETTARLYAGTGDGTAFAQGEDATAAGSNATADADYSSAFGASSQ 1162 T + + A A T++T A + A A+ A S+ A+ YS A G S+ Sbjct: 122 TAQKDGVAIGARASTSDTGV---AVGFNSKADAKNSVAIGHSSHVAANHGYSIAIGDRSK 178 Query: 1163 ATAIGAVAIG 1172 +V+IG Sbjct: 179 TDRENSVSIG 188
>BACYPHPHTASE#Salmonella/Yersinia modular tyrosine phosphatase signature. Length = 468 Score = 30.5 bits (68), Expect = 0.012 Identities = 23/72 (31%), Positives = 28/72 (38%), Gaps = 13/72 (18%) Query: 135 RPYPFLRLHHGVGKVWAGEEAVETSSGEEDRAQEDVELTDLRQLGIATLGTLKEHPR--- 191 R P HHG G+ A + + G E RA+ LT LR TL PR Sbjct: 164 RERPHTSGHHGAGEARATAPSTVSPYGPEARAELSSRLTTLRN----TLAPATNDPRYLQ 219 Query: 192 ------IKRFRD 197 + RFRD Sbjct: 220 ACGGEKLNRFRD 231
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.8 bits (85), Expect = 1e-05 Identities = 15/59 (25%), Positives = 25/59 (42%) Query: 70 DEAHVLNVCIAPEAQSQGHGRVLLRALIKAACDRGARRAFLEVRPSNPSAIALYHSEGF 128 A + ++ +A + + +G G LL I+ A + LE + N SA Y F Sbjct: 88 GYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 28.6 bits (63), Expect = 0.013 Identities = 23/71 (32%), Positives = 30/71 (42%), Gaps = 11/71 (15%) Query: 34 PEPAPAVAEAP--APVREPTRPQHAA--PAPSAAPAARRNAPAAPSEPP-------ADVS 82 P+ P AEAP P+ E + ++ A PAP+ P R N P P Sbjct: 313 PDLTPGSAEAPNAQPLPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTDGQPG 372 Query: 83 VRPSAPAAPRR 93 RP +PA P R Sbjct: 373 TRPDSPAVPDR 383
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 187 bits (477), Expect = 5e-59 Identities = 91/349 (26%), Positives = 140/349 (40%), Gaps = 48/349 (13%) Query: 5 LVTGGAGFIGGNFVLEAVSRGIRVVNLDALT--YAGNLNTL-ASLEGNADHIFVKGDIGD 61 LVTG AGFIG + + G +VV +D L Y +L L F K D+ D Sbjct: 4 LVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDLAD 63 Query: 62 GALVTRLLQEHQPDAVLNFAAESHVDRSIEGPGAFIQTNVVGTLALLEAVRDYWKALPDT 121 +T L + V V S+E P A+ +N+ G L +LE R Sbjct: 64 REGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHN------- 116 Query: 122 RRDAFRFLHVSTDEVYGTLGETGKFTETTPYA-PNSPYSASKAASDHLVRAFHHTYGLPV 180 L+ S+ VYG L F+ P S Y+A+K A++ + + H YGLP Sbjct: 117 --KIQHLLYASSSSVYG-LNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPA 173 Query: 181 LTTNCSNNYGPYHFPEKLIPLVIAKALAGEPLPVYGDGKQVRDWLFVSDHCEAI------ 234 YGP+ P+ + L G+ + VY GK RD+ ++ D EAI Sbjct: 174 TGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDV 233 Query: 235 ---------------RTVLAKGRVGETYNVGGNSERQNIEVVQAICALLDQHRPREDGKP 279 +A RV YN+G +S + ++ +QA+ L Sbjct: 234 IPHADTQWTVETGTPAASIAPYRV---YNIGNSSPVELMDYIQALEDALG---------- 280 Query: 280 RESQIAYVTDRPGHDRRYAIDASKLKDELGWEPAYTFEQGIAQTVDWYL 328 E++ + +PG + D L + +G+ P T + G+ V+WY Sbjct: 281 IEAKKNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYR 329
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 112 bits (282), Expect = 7e-31 Identities = 68/326 (20%), Positives = 122/326 (37%), Gaps = 39/326 (11%) Query: 11 RVLVSGASGFTGRYMSQQLKEQGCTVIGVGTRCDGAGTSATDE-----------FWPMDL 59 + LV+GA+GF G ++S++L E G V+G+ D S F +DL Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 60 RDAADVARVVAQAQADYVVHLAAVAFVGH--GDADDFYRVNLLGTRNLLQALAASQHRPE 117 D + + A + V V + + + NL G N+L+ ++ + Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILE--GCRHNKIQ 119 Query: 118 RVLIASSANVYG-NATEGVIDESVTPSPANDYAVSKLAMEYVASLWHE--RLPLVIARPF 174 +L ASS++VYG N + P + YA +K A E +A + LP R F Sbjct: 120 HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFF 179 Query: 175 NYTGVGQATNFLIPKIVSHFASRASSIEL-GNTEVWRDFGDVRSVVLAYRKLLQAPA--- 230 G + + K SI++ ++ RDF + + A +L Sbjct: 180 TVYGPWGRPDMALFKFTKAMLE-GKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHAD 238 Query: 231 --------------AEGQIVNVCSGVASSLSDIIRICSKITGHDIDVQVNPAFVRQNEVR 276 A ++ N+ + L D I+ G + + P ++ +V Sbjct: 239 TQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLP--LQPGDVL 296 Query: 277 KLLGSNARLQELIGDWQSLALEDTLR 302 + L E+IG ++D ++ Sbjct: 297 ETSADTKALYEVIGFTPETTVKDGVK 322
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 85.6 bits (212), Expect = 5e-21 Identities = 66/343 (19%), Positives = 115/343 (33%), Gaps = 35/343 (10%) Query: 5 LITGISGQDGAYLAQLLLDKGYRVFG-----TYRRTSSVNFWRIEELGIAAHPNLNLIEY 59 L+TG +G G ++++ LL+ G++V G Y S + L + A P + Sbjct: 4 LVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVS----LKQARLELLAQPGFQFHKI 59 Query: 60 DLTDLGSSIRMLESTGATEVYNLAAQSFVGVSFDQPTTTAQITGIGPVHLLEAIRQVNRD 119 DL D + S V+ + V S + P A G +++LE R Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ 119 Query: 120 IRFYQASTSEMFGKVQAVPQIESTPF-YPRSPYGVAKLYAHWMTVNYRESYDIFGCSGIL 178 AS+S ++G + +P +P S Y K M Y Y + Sbjct: 120 -HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRF 178 Query: 179 FNHESPLRGRE-----FVTRKITDSVAKIKLGLLDCMELGNLDAKRDWGFAREYVEGMWR 233 F P GR T+ + + + I + KRD+ + + E + R Sbjct: 179 FTVYGP-WGRPDMALFKFTKAMLEGKS-IDV-------YNYGKMKRDFTYIDDIAEAIIR 229 Query: 234 MLQA-DEPDTFVLATNRTETVRDFVSMAFK-GAGIDVEFRGKDAEETAVDTATGKVVMRI 291 + DT T + G VE + + + Sbjct: 230 LQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVEL------MDYIQALEDALGIEA 283 Query: 292 NPKF--HRPAEVELLIGDPEKATRILGWKPETTLEQLCQMMVE 332 +P +V D + ++G+ PETT++ + V Sbjct: 284 KKNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVN 326
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 62.0 bits (150), Expect = 4e-12 Identities = 47/235 (20%), Positives = 83/235 (35%), Gaps = 6/235 (2%) Query: 459 YQRLQKALLGYNARLSAVHIETEHHRVELAARGAAIEHLRDSTLQDQERTQAFEQGVAAA 518 + L + + + L+ + + I+ L ++ + A Sbjct: 83 LKDHNDELTEELSNAKE---KLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTAD 139 Query: 519 EERYKRLEEESEKLAAWAKGLEAQTIESNRDKEALAALNAELESDKAALATRIASLGQEL 578 + K LE E LAA LE + A +A LE++KAAL R A L + L Sbjct: 140 SAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKAL 199 Query: 579 EERQRARELAELLAADVGRLTEERDAARSDLLDTQSVVEQHQATITALEARVAVQQQQIS 638 E A + +A + L E+ A + D + +E TA A++ + + + Sbjct: 200 EG---AMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKA 256 Query: 639 GLESSRDQERNRLRELQVDLSRSMDGTASAREYIRELEMAVDALEGQINSLHGSR 693 LE+ + + L + + LE LE Q L+ +R Sbjct: 257 ALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANR 311 Score = 50.8 bits (121), Expect = 1e-08 Identities = 39/239 (16%), Positives = 78/239 (32%), Gaps = 4/239 (1%) Query: 459 YQRLQKALLGYNARLSAVHIETEHHRVELAARGAAIEHLRDSTLQDQERTQAFEQGVAAA 518 + AR + + E A A I+ L R E+ + A Sbjct: 108 LSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGA 167 Query: 519 EERYKRLEEESEKLAAWAKGLEAQTIESNRDKEALAALNAELESDKAALATRIASLGQEL 578 + + L A LEA+ E + E + + L A+L Sbjct: 168 MNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARK 227 Query: 579 EERQRARELAELLAADVGRLTEERDAARSDLLDTQSVVEQHQATITALEARVAVQQQQIS 638 + ++A E A + + +A ++ L Q+ +E+ + + + + Sbjct: 228 ADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLE 287 Query: 639 GLESSRDQERNRLRELQVDLSRSMDGT----ASAREYIRELEMAVDALEGQINSLHGSR 693 +++ + E+ L L+ + ++RE ++LE LE Q SR Sbjct: 288 AEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASR 346 Score = 38.9 bits (90), Expect = 8e-05 Identities = 45/221 (20%), Positives = 77/221 (34%), Gaps = 7/221 (3%) Query: 442 LQQADATPHSAPEWVTIYQRLQKALLGYNARLSAVHIETEHHRVELAARGAAIEHLRDST 501 A + + A L A E + EL A+E + + Sbjct: 220 KAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEK---ALEGAMNFS 276 Query: 502 LQDQERTQAFEQGVAAAEERYKRLEEESEKLAAWAKGLEAQTIESNRDKEALAALNAELE 561 D + + E AA E LE +S+ L A + L S K+ L A + +LE Sbjct: 277 TADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLE 336 Query: 562 SDKAALATRIASLGQELEERQRARELAEL----LAADVGRLTEERDAARSDLLDTQSVVE 617 SL ++L+ + A++ E L R + R DL ++ + Sbjct: 337 EQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKK 396 Query: 618 QHQATITALEARVAVQQQQISGLESSRDQERNRLRELQVDL 658 Q + + +++A ++ LE S+ ELQ L Sbjct: 397 QVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKL 437 Score = 30.0 bits (67), Expect = 0.043 Identities = 26/91 (28%), Positives = 36/91 (39%), Gaps = 16/91 (17%) Query: 516 AAAEERYKRLEEESEKLAAWAKGL--------------EAQTIESNRDKEALAALNAELE 561 E +++LEE+++ A + L E E+N AL LN ELE Sbjct: 361 KQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELE 420 Query: 562 SDKAALATRIASLGQELEERQRARELAELLA 592 K A L +LE A+ L E LA Sbjct: 421 ESKKLTEKEKAELQAKLE--AEAKALKEKLA 449
>INTIMIN#Intimin signature. Length = 939 Score = 32.3 bits (73), Expect = 0.002 Identities = 32/113 (28%), Positives = 45/113 (39%), Gaps = 20/113 (17%) Query: 23 AEDTDDRFQIRLGAMNIDNDNTLRGNTVVAGNEISLDQDFD-------FGGKEW----EP 71 A D RF LGA + G + +DQDF GG+ W + Sbjct: 248 ARYIDSRFTANLGA----GQRFFLPEN-MLGYNVFIDQDFSGDNTRLGIGGEYWRDYFKS 302 Query: 72 RIDGVFRMSTRQRLIFDYFKYDKDRRETLGEDVSAGGFTVPSGSFIKGELKYQ 124 ++G FRMS Y K D D R G D+ G+ +PS + +L Y+ Sbjct: 303 SVNGYFRMSGWHE---SYNKKDYDERPANGFDIRFNGY-LPSYPALGAKLMYE 351
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 29.3 bits (66), Expect = 0.028 Identities = 23/86 (26%), Positives = 36/86 (41%), Gaps = 12/86 (13%) Query: 14 GCACTSLSAHAQTTVITAARLLDVQAGRYVERPQIDVVAGRITRVGRQGDPLPPQAQRID 73 G + + A TVIT A +LD + + I + GRI +G+ G+P I Sbjct: 57 GQSQVTREGGAVDTVITNALILDHWG---IVKADIGLKDGRIAAIGKAGNPDMQPGVTII 113 Query: 74 LGERT---------LLPGLIDMHVHL 90 +G T + G +D H+H Sbjct: 114 VGPGTEVIAGEGKIVTAGGMDSHIHF 139
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.8 bits (67), Expect = 0.031 Identities = 12/37 (32%), Positives = 21/37 (56%) Query: 48 EVPSSVAGVVKEIKVKVGDSLSQGALVALIEVADADA 84 E+ +VKEI VK G+S+ +G ++ + A+A Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEA 134
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 33.9 bits (77), Expect = 0.003 Identities = 58/310 (18%), Positives = 108/310 (34%), Gaps = 19/310 (6%) Query: 319 EGISTGFAHSASAASAHWSTAMTAQERAQQ-AQTEQLQHALAQMAQQTTALQDSVGQAVQ 377 +G S + +A A+A WSTA + +A+Q A+ + A A+ AL + V Sbjct: 40 KGGSKSESSAAIHATAKWSTAQLKKTQAEQAARAKAAAEAQAKAKANRDALTQRLKDIVN 99 Query: 378 QQLGVLTDGFERSTSAAAANWQAALTAQEQAQQALTQQLQSTLAQLAAQTTALQD--NLG 435 + L +T A AN A E + L + + + A A Q+ Sbjct: 100 EALRHNASRTPSATELAHANNAA--MQAEDERLRLAKAEEKARKEAEAAEKAFQEAEQRR 157 Query: 436 QAVQQQLAALNDGVAHSTAAAAAGWAAVLAEHQQST---QALSAQLQRTVEQIAEHSTTL 492 + ++++ A + A A A L+E ++ Q + Q V ++ TL Sbjct: 158 KEIEREKAETERQL--KLAEAEEKRLAALSEEAKAVEIAQKKLSAAQSEVVKMDGEIKTL 215 Query: 493 QDGVGQAVQQQ------LDGLSTGFAASTATAAQTWTAAASEQQRANQSLTDALHTTLTH 546 + ++ + L G A ++A + RAN L + T Sbjct: 216 NSRLSSSIHARDAEMKTLAGKRNELAQASAKYKELDELVKKLSPRANDPLQNRPFFEATR 275 Query: 547 -FASTFEARSEAL--VDAVSARLEQSSSQTADAWNAALAQQQQASAELAAQHQGALSAAT 603 + R E V A R+ + ++ A +A +A H+ + Sbjct: 276 RRVGAGKIREEKQKQVTASETRINRINADITQIQKAISQVSNNRNAGIARVHEAEENLKK 335 Query: 604 ASSEAHAAAL 613 A + + + Sbjct: 336 AQNNLLNSQI 345
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 76.5 bits (188), Expect = 1e-18 Identities = 41/143 (28%), Positives = 62/143 (43%), Gaps = 16/143 (11%) Query: 68 ALAAPLAAGRVTLVNGRIGIRGSVLFALNSDQLQPEGREVLKSLAAPLSEYLVSREEILM 127 + AP A + ++ VLF N L+PEG+ L L + LS + + Sbjct: 198 PVVAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSV-V 256 Query: 128 ISGFTDDRPVLDSNRRYADNWELSAQRALTVTRALIAEGVPASSVFAAAFGSQQPVDSNA 187 + G+TD + Y N LS +RA +V LI++G+PA + A G PV N Sbjct: 257 VLGYTDRI----GSDAY--NQGLSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNT 310 Query: 188 DETRR---------AKNRRVEIA 201 + + A +RRVEI Sbjct: 311 CDNVKQRAALIDCLAPDRRVEIE 333
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 70.5 bits (172), Expect = 2e-16 Identities = 41/186 (22%), Positives = 77/186 (41%), Gaps = 5/186 (2%) Query: 2 KTVLISGSGSGMGLLTAQTLMRAGYVVYAGVRDPDGRSKERRHALEDYARAHAAQVRVVD 61 K I+G+ G+G A+TL G + A +P E+ + +A A Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNP-----EKLEKVVSSLKAEARHAEAFP 63 Query: 62 MDIHSEASCQRAVEQVVAEHGHLDVVIHNAAHLYIGMAEGFTAEQLADSFNTNAVGAHRL 121 D+ A+ ++ E G +D++++ A L G+ + E+ +F+ N+ G Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 122 NRAALPQLRKQGHGTLLYVGSTITRIVAPFMMPYVAGKYALDAVAETTAYEVQPLGIETV 181 +R+ + + G+++ VGS + M Y + K A + E+ I Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 182 IVMPGT 187 IV PG+ Sbjct: 184 IVSPGS 189
>PF05844#YopD protein Length = 295 Score = 27.3 bits (60), Expect = 0.033 Identities = 16/49 (32%), Positives = 24/49 (48%), Gaps = 7/49 (14%) Query: 9 STHTALPAVLLAAVLWLPGAQAASVAAPAAAAQHDTPHMAAHNKQLVDI 57 +T A+P+ +A PGA SV P AAA + P + A V++ Sbjct: 10 ATQAAIPSEPIA-----PGAAGRSVGTPQAAA--ELPQVPAARADRVEL 51
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 41.1 bits (96), Expect = 5e-07 Identities = 15/61 (24%), Positives = 26/61 (42%), Gaps = 1/61 (1%) Query: 82 SVEHSIYVHRDHRGKGLGRTLLQLLIDAAQARGVHVLVGGIDASNAASIALHEQFGFTHA 141 +E I V +D+R KG+G LL I+ A+ L+ N ++ + + F Sbjct: 91 LIED-IAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIG 149 Query: 142 G 142 Sbjct: 150 A 150
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 35.0 bits (80), Expect = 2e-04 Identities = 26/155 (16%), Positives = 43/155 (27%), Gaps = 9/155 (5%) Query: 43 VQQQKKLMTAPAAMPLPSSAAAPVSARPAPARAATQAPPVAAPAPQAPAAVPTATTA--- 99 V+ +K + + +P A P V PQ+ T Sbjct: 1114 VETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAK 1173 Query: 100 -TSSLPPPPLFECTAHDNGRYFTE--ESEPATRCLPMQVTNLAGGPAQGGGSACEVVTDR 156 TSS P+ E T + G E E+ P + + P + V Sbjct: 1174 ETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRS---VRSV 1230 Query: 157 CAPVPDQSLCAAWRQRAEQAEAAWRFSDEAQSAAR 191 V + + R + ++ S AR Sbjct: 1231 PHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDAR 1265 Score = 29.6 bits (66), Expect = 0.009 Identities = 30/176 (17%), Positives = 52/176 (29%), Gaps = 11/176 (6%) Query: 40 PKGVQQQKKLMTAPAAMPLPSSAAAPVSARPAPARAATQAPPVAAPAPQAPAAVPTATTA 99 P+ ++ + + T P A P A PV PAP A P+ TT Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAP----ATPSETTE 1038 Query: 100 TSSLPPPPLFECTAHDNGRYFTEESEPATRCLPMQVTNLAGGPAQGGGSACEVVTDRCAP 159 T + + + E+ R +V A + EV Sbjct: 1039 TVAENSKQESKTVEKNEQD--ATETTAQNR----EVAKEAKSNVKANTQTNEVAQSGSET 1092 Query: 160 VPDQSLCAAWRQRAEQAEAAWRFSDEAQSAARKQRYDQARRVMDES-RCAGTPATP 214 Q+ E+ E A +++ Q + ++ E+ + PA Sbjct: 1093 KETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARE 1148
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 112 bits (282), Expect = 3e-32 Identities = 75/253 (29%), Positives = 112/253 (44%), Gaps = 10/253 (3%) Query: 8 LDGQTALITGASAGIGLAIARELLGFGADLLMVARDADALAQARDELAEEFPERELHGLA 67 ++G+ A ITGA+ GIG A+AR L GA + A D + + + + R Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIA--AVDYNPEKLEKVVSSLKAEARHAEAFP 63 Query: 68 ADVSDDEERRAILDWVEDHADGLHLLINNAGGNITRAAIDYTEDEWRGIFETNVFSAFEL 127 ADV D I +E + +L+N AG +++EW F N F Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 128 SRYAHPLLTRHAASAIVNVGSVSGITHVRSGAPYGMTKAALQQMTRNLAVEWAEDGIRVN 187 SR + + +IV VGS S A Y +KAA T+ L +E AE IR N Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 188 AVAPWYIRTRRTSGPLSDPDYYEQVIERT--------PMRRIGEPEEVAAAVGFLCLPAG 239 V+P T +D + EQVI+ + P++++ +P ++A AV FL Sbjct: 184 IVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 240 SYITGECIAVDGG 252 +IT + VDGG Sbjct: 244 GHITMHNLCVDGG 256
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.4 bits (68), Expect = 0.004 Identities = 21/98 (21%), Positives = 35/98 (35%), Gaps = 17/98 (17%) Query: 31 PASPVATPAAPAAPARSIPSAAQQRARWDAL--------TPAQRTELRARYAAWKALTA- 81 + + TP A S+PS ++ AR D TP++ TE A + ++ T Sbjct: 993 DTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVE 1052 Query: 82 --------TDKVVLRQARERLQALPDDQQRALRTQFGA 111 T A+E + + Q Q G+ Sbjct: 1053 KNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGS 1090
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 50.2 bits (120), Expect = 8e-09 Identities = 30/158 (18%), Positives = 60/158 (37%), Gaps = 22/158 (13%) Query: 55 AATQDVPVYATALGTVTAL-NTVTVNPQVSGQLMSLNFQEGQEVKKGALLAQIDPRT--- 110 + V + ATA G +T + + P + + + +EG+ V+KG +L ++ Sbjct: 75 SVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEA 134 Query: 111 ----LQASYDQALAAKRQNQALLATA---RVNYQRSNDPAYKQYVS-----------RTD 152 Q+S QA + + Q L + ++ + D Y Q VS + Sbjct: 135 DTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQ 194 Query: 153 LDTQRNQVAQYEAAVAANDAQMRSAQVQLQFTRVTAPI 190 T +NQ Q E + A+ + ++ + + Sbjct: 195 FSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRV 232 Score = 34.4 bits (79), Expect = 9e-04 Identities = 22/178 (12%), Positives = 62/178 (34%), Gaps = 29/178 (16%) Query: 93 EGQEVKKGALLAQIDPRTLQASYDQ-------ALAAKR----------QNQALLATARVN 135 + + ++ +LA+I+ + ++ +L K+ +N+ + A + Sbjct: 210 DKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELR 269 Query: 136 YQRSNDPAYKQYVSRTDLD-TQRNQVAQYEAAVAANDAQMRSAQV---------QLQFTR 185 +S + + + Q+ + E + + Q + Sbjct: 270 VYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASV 329 Query: 186 VTAPIDGIAGIRGV-DVGNIVSTTSTIVTLT-QIRPIYVSFSLPERELPAVRSGQAAT 241 + AP+ V G +V+T T++ + + + V+ + +++ + GQ A Sbjct: 330 IRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAI 387 Score = 31.7 bits (72), Expect = 0.005 Identities = 11/104 (10%), Positives = 35/104 (33%), Gaps = 1/104 (0%) Query: 79 NPQVSGQLMSLNFQEGQEVKKGALLAQIDPRTLQASYDQALAAKRQNQALLATARVNYQR 138 +V + Q + +++ +A LA + + L + Sbjct: 181 EEEVLRLTSLIKEQFSTW-QNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDD 239 Query: 139 SNDPAYKQYVSRTDLDTQRNQVAQYEAAVAANDAQMRSAQVQLQ 182 + +KQ +++ + Q N+ + + +Q+ + ++ Sbjct: 240 FSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEIL 283
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 731 bits (1888), Expect = 0.0 Identities = 300/1072 (27%), Positives = 503/1072 (46%), Gaps = 65/1072 (6%) Query: 4 STIFIRRPIATSLLMAGILLLGILGYRQLPVSALPEIDAPSLVVSTQYPGANATTMASLV 63 + FIRRPI +L +++ G L QLPV+ P I P++ VS YPGA+A T+ V Sbjct: 2 ANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTV 61 Query: 64 TTPLERQLGQISGLQMMTSDS-SAGLSTIILQFSMDRDIDIAAQDVQAAIRQAT--LPSS 120 T +E+ + I L M+S S SAG TI L F D DIA VQ ++ AT LP Sbjct: 62 TQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE 121 Query: 121 LPYQPVYNRVNPADAAILTLKLTSDT--LPLREVNRYADAILAQRLSQVPGVGLVSIAGN 178 + Q + + + ++ SD +++ Y + + LS++ GVG V + G Sbjct: 122 VQQQGIS-VEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 179 VRPAVRIQVNPAQLSNMGLTMESLRSALTQTNVSAPKGSLN------GKTQSYSIGTNDQ 232 A+RI ++ L+ LT + + L N G L G+ + SI + Sbjct: 181 QY-AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 233 LTDAAQYRETIISYN-NGAPVRLADVAKVVDGVENDQLAAWADGKPAVLLEIRRQPGANI 291 + ++ + + N +G+ VRL DVA+V G EN + A +GKPA L I+ GAN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 292 VQTVEQIRSILPQLQGVLPADVHLDVFSDRTETIRASVHEVKFTLVLTIFLVVAVIFVFL 351 + T + I++ L +LQ P + + D T ++ S+HEV TL I LV V+++FL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 352 RRLWATIIPSVAVPLSLAGTFGVMAFAGMSLDNLSLMALVVATGFVVDDAIVMIENIVRY 411 + + AT+IP++AVP+ L GTF ++A G S++ L++ +V+A G +VDDAIV++EN+ R Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 412 IEQGKSGP-EAAEIGARQIGFTVLSLTVSLVAVFLPLLLMPGVTGRLFHEFAWVLSIAVV 470 + + K P EA E QI ++ + + L AVF+P+ G TG ++ +F+ + A+ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 471 ISMLVSLTLTPMMCAYLLKPDALPEGEDAHERAAAEGKTNLWTRTVGVYERSLDWVLDHQ 530 +S+LV+L LTP +CA LLKP + E ++ + +V Y S+ +L Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHE--NKGGFFGWFNTTFDHSVNHYTNSVGKILGST 537 Query: 531 PLTLAVAIGAVALTVVLYVAIPKGLLPEQDTGLITGVVQVDQNVAFPQMEQRTQAVAAAL 590 L + VA VVL++ +P LPE+D G+ ++Q+ + ++ V Sbjct: 538 GRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYY 597 Query: 591 RKDPA--VTGVAAFIGAGSMNPTLNQGQLSIVLKTRGDRD----DLETVVARLQKAVSGI 644 K+ V V G N G + LK +R+ E V+ R + + I Sbjct: 598 LKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKI 657 Query: 645 PGVALFLKPVQDV-TLDTRVAATEYQYSMADVDSTELASWA-TRMTEAMRKLPELADVDN 702 + + + L T A + L + A + L V Sbjct: 658 RDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRP 717 Query: 703 NLANQGRALELSIDRDKASMLGVPMQTIDDTLYDAFGQRQISTIFTELNQYRVVLEVAPE 762 N +L +D++KA LGV + I+ T+ A G ++ ++ ++ + Sbjct: 718 NGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAK 777 Query: 763 FRSSTALMNQLAVASNGSGALTGTNATSFGQVTSSNSSTATGVGNQNTGIVVGAGSIIPL 822 FR +++L V S G ++P Sbjct: 778 FRMLPEDVDKLYVRSA-------------------------------------NGEMVPF 800 Query: 823 AALAEAKVTNTPLVVSHQQQLPAVTISFNLAPGHSLSQAVAAIEQARADLKIPTQVHAEF 882 +A + + LP++ I APG S A+A +E + K+P + ++ Sbjct: 801 SAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMALMENLAS--KLPAGIGYDW 858 Query: 883 VGKAAEFTGSQTDIVWLLLASIVVIYIVLGVLYESYIHPLTIISTLPPAGVGALLALMVC 942 G + + S L+ S VV+++ L LYES+ P++++ +P VG LLA + Sbjct: 859 TGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLF 918 Query: 943 GLSLSVDGIVGIVLLIGIVKKNAIMMIDFAIEA-RRTGVNAHEAIRRACLLRFRPIMMTT 1001 V +VG++ IG+ KNAI++++FA + + G EA A +R RPI+MT+ Sbjct: 919 NQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTS 978 Query: 1002 AAAMLGALPLALGTGIGSELRRPLGIAIVGGLLLSQLVTLYTTPVIYLYMER 1053 A +LG LPLA+ G GS + +GI ++GG++ + L+ ++ PV ++ + R Sbjct: 979 LAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRR 1030 Score = 73.3 bits (180), Expect = 3e-15 Identities = 72/454 (15%), Positives = 156/454 (34%), Gaps = 48/454 (10%) Query: 614 QGQLSIVLKTRGDRDD-LETVVARLQKAVSGIPGVALFLKPVQDVTLDTRVAATEYQYSM 672 +++ ++ D D V +LQ A +P + + + + + Sbjct: 87 SVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQQQGISVEKSSSSYLMVAGFVSDN 146 Query: 673 ADVDSTELASWATR-MTEAMRKLPELADVDNNLANQGRALELSIDRDKASMLGVPMQTID 731 +++ + + + + +L + DV L A+ + +D D Sbjct: 147 PGTTQDDISDYVASNVKDTLSRLNGVGDV--QLFGAQYAMRIWLDADL------------ 192 Query: 732 DTLYDAFGQRQISTIFTELNQYRVVLEVAPEFRSSTALMNQLAVASNGS-GALTGTNATS 790 LN+Y++ L Q + G G Sbjct: 193 ------------------LNKYKLTPV-----DVINQLKVQNDQIAAGQLGGTPALPGQQ 229 Query: 791 FGQVTSSNSSTATGVGNQNTGIVVGA-GSIIPLAALAEAKVT--NTPLVVSHQQQLPAVT 847 + + + V + GS++ L +A ++ N ++ + PA Sbjct: 230 LNASIIAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGK-PAAG 288 Query: 848 ISFNLAPGHSLSQAVAAIEQARADLK--IPTQVHAEFVGKAAEF-TGSQTDIVWLLLASI 904 + LA G + AI+ A+L+ P + + F S ++V L +I Sbjct: 289 LGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAI 348 Query: 905 VVIYIVLGVLYESYIHPLTIISTLPPAGVGALLALMVCGLSLSVDGIVGIVLLIGIVKKN 964 +++++V+ + ++ L +P +G L G S++ + G+VL IG++ + Sbjct: 349 MLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDD 408 Query: 965 AIMMIDFAIEARR-TGVNAHEAIRRACLLRFRPIMMTTAAAMLGALPLALGTGIGSELRR 1023 AI++++ + EA ++ ++ +P+A G + R Sbjct: 409 AIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYR 468 Query: 1024 PLGIAIVGGLLLSQLVTLYTTPVIYLYMERAGER 1057 I IV + LS LV L TP + + + Sbjct: 469 QFSITIVSAMALSVLVALILTPALCATLLKPVSA 502
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 752 bits (1943), Expect = 0.0 Identities = 287/1034 (27%), Positives = 488/1034 (47%), Gaps = 26/1034 (2%) Query: 3 ISAPFIKRPIGTSLLAIGLFVIGLMCYLRLGVAALPNIQIPVIFVHATQSGADASTMAST 62 ++ FI+RPI +LAI L + G + L+L VA P I P + V A GADA T+ T Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 63 VTAPLERHLGQLPGIDRMRSSS-SESSSMVFMIFQSNRDIDSAAQDVQTAINSAQSDLPS 121 VT +E+++ + + M S+S S S + + FQS D D A VQ + A LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 122 GLGTPMYQKANPNDDPVIAIALTSDT--QSADELYNVADSLLAQRLRQITGISSVDIAGA 179 + + ++ SD + D++ + S + L ++ G+ V + GA Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 180 STPAVRVDVDLRALNALGLTPDDLRNAVRAANVTSPTGFL------SDGNTTMAIIANDS 233 A+R+ +D LN LTP D+ N ++ N G L +IIA Sbjct: 181 QY-AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 234 VAKAADFAQLAISTQSNGRIVRLGDVATVYDGQQDAYQAAWFNGKPAVVMYAFTRAGANI 293 +F ++ + S+G +VRL DVA V G ++ A NGKPA + GAN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 294 VETVDQVKAQIPELRAYLQPGTTLTPYFDRTPTIRASLHEVQATLMISLAMVVLTMALFL 353 ++T +KA++ EL+ + G + +D TP ++ S+HEV TL ++ +V L M LFL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 354 RRLAPTLIAAVTVPLSLAGSALVMYVLGFTLNNLSLLALVIAIGFVVDDAIVVIENIMRH 413 + + TLI + VP+ L G+ ++ G+++N L++ +V+AIG +VDDAIVV+EN+ R Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 414 L-DEGMPRLQAALTGAREIGFTIVSITASLVAVFIPMLFASGMVGAFFREFTVTLVAAIV 472 + ++ +P +A +I +V I L AVFIPM F G GA +R+F++T+V+A+ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 473 VSMLVSLTLTPALCSRFLSAHTAP--ETPSRFGAWLDRMHDRMLAVYTVALDFSLRHALL 530 +S+LV+L LTPALC+ L +A E F W + D + YT ++ L Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 531 LSLTPLVLIAATIFLGGAVKKGSFPPQDTGLIWGRANSSATVSFADMVSRQRRITDMLMA 590 L +++A + L + P +D G+ A + ++TD + Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 591 DP-----AVKTVGARLGSGRQGSSASLNIELKKRDE--GRRETTAQVVARLSAKADRYPD 643 + +V TV SG+ ++ + LK +E G + V+ R + + Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIR- 658 Query: 644 LDLRLRAIQDLPSDGGGGTSQGAQYRVSLQGNDLAQLQEWLPKVQAALKKNP-RLRDVGT 702 D + G + + G L + ++ ++P L V Sbjct: 659 -DGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRP 717 Query: 703 DVDTSGLRQNIVIDRAKAARLGISVGAIDGALYGAFGQRSISTIYSDLNQYSVVVNALPS 762 + + + +D+ KA LG+S+ I+ + A G ++ + V A Sbjct: 718 NGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAK 777 Query: 763 QTATPKALDEVFVPNRAGQMAPITAVATQVPGLAPPQITHDNQYSTMDLSYNLAPGVSTG 822 P+ +D+++V + G+M P +A T P++ N +M++ APG S+G Sbjct: 778 FRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSG 837 Query: 823 EADLIIKTTVEGLRMPGDIRISDGGGF-NVQLNPNSMGVLLLAAVLTVYIVLGMLYESLI 881 +A +++ ++P I G +L+ N L+ + + V++ L LYES Sbjct: 838 DAMALMENLAS--KLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWS 895 Query: 882 HPVTILSTLPAAGVGALLALFITNTELSVISMIALVLLIGIVKKNAIMMIDFALVAQREH 941 PV+++ +P VG LLA + N + V M+ L+ IG+ KNAI++++FA + Sbjct: 896 IPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKE 955 Query: 942 GKDARAAAREASIVRFRPIMMTTMVAILAAVPLAVGLGEGSELRRPLGIAMIGGLVFSQG 1001 GK A A +R RPI+MT++ IL +PLA+ G GS + +GI ++GG+V + Sbjct: 956 GKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATL 1015 Query: 1002 LTLLSTPALYVIFS 1015 L + P +V+ Sbjct: 1016 LAIFFVPVFFVVIR 1029 Score = 112 bits (281), Expect = 4e-27 Identities = 80/506 (15%), Positives = 170/506 (33%), Gaps = 31/506 (6%) Query: 2 NISAPFIKRPIGTSLLAIGLFVIGLMCYLRLGVAALPNIQIPVIFVHA-TQSGADASTMA 60 N + L+ + ++ +LRL + LP V +GA Sbjct: 528 NSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQ 587 Query: 61 STVTAPLERHLGQLPGID--------RMRSSSSESSSMVFMIFQSNRDIDSAAQDVQTAI 112 + + +L S ++++ M F+ + + + + I Sbjct: 588 KVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVI 647 Query: 113 NSAQSDL---PSGLGTPMYQKANPNDDPVIAIALTSDTQSA-----DELYNVADSLLAQR 164 + A+ +L G P + A + D L + LL Sbjct: 648 HRAKMELGKIRDGFVIPF--NMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMA 705 Query: 165 LRQITGISSVDIAG-ASTPAVRVDVDLRALNALGLTPDDLRNAVRAANVTSPTGFLSDGN 223 + + SV G T +++VD ALG++ D+ + A + D Sbjct: 706 AQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRG 765 Query: 224 TTMAIIA---NDSVAKAADFAQLAISTQSNGRIVRLGDVATVYDGQQDAYQAAWFNGKPA 280 + D +L + + +NG +V T + + + +NG P+ Sbjct: 766 RVKKLYVQADAKFRMLPEDVDKLYVRS-ANGEMVPFSAFTTSHWVYG-SPRLERYNGLPS 823 Query: 281 VVMYAFTRAGANIVETVDQVKAQIPELRAYLQPGTTLTPYFDRTPTIRASLHEVQATLMI 340 + + G + A + L + L G + + R S ++ A + I Sbjct: 824 MEIQGEAAPGTS----SGDAMALMENLASKLPAGIGYD-WTGMSYQERLSGNQAPALVAI 878 Query: 341 SLAMVVLTMALFLRRLAPTLIAAVTVPLSLAGSALVMYVLGFTLNNLSLLALVIAIGFVV 400 S +V L +A + + + VPL + G L + + ++ L+ IG Sbjct: 879 SFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSA 938 Query: 401 DDAIVVIENIM-RHLDEGMPRLQAALTGAREIGFTIVSITASLVAVFIPMLFASGMVGAF 459 +AI+++E EG ++A L R I+ + + + +P+ ++G Sbjct: 939 KNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGA 998 Query: 460 FREFTVTLVAAIVVSMLVSLTLTPAL 485 + ++ +V + L+++ P Sbjct: 999 QNAVGIGVMGGMVSATLLAIFFVPVF 1024
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 29.2 bits (65), Expect = 0.005 Identities = 22/92 (23%), Positives = 27/92 (29%), Gaps = 11/92 (11%) Query: 46 FTDGAQIHYDTEAHALQATLPSGGTATITADGGITLNGPLTVN----GETMLNGDATITG 101 T+ A +H L G IT++GPL VN G + A Sbjct: 416 TTNAAHLHIGKGGINLSNQASGRSLLVENLTGNITVDGPLRVNNQVGGYALAGSSANFEF 475 Query: 102 TATATTD----VLGGGISLKH---HKTTGVTA 126 A T ISL K TA Sbjct: 476 KAGTDTKNGTATFNNDISLGRFVNLKVDAHTA 507
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 39.4 bits (92), Expect = 9e-06 Identities = 16/27 (59%), Positives = 18/27 (66%) Query: 1 MHLLITGGTGFIGQALCPALLEAGHQV 27 M L+TG GFIG + LLEAGHQV Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQV 27
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 82.2 bits (203), Expect = 2e-20 Identities = 26/155 (16%), Positives = 61/155 (39%), Gaps = 5/155 (3%) Query: 2 HLLLVEDDTMLADAIYDGVRQQSWTIDHVGTAAAARTALVEHHYTAVLLDIGLPGDSGLT 61 +L+ +DD + + + + + + AA + V+ D+ +P ++ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VIRYMRGHYDATPVIALTARGQLTDRIRGLDAGADDYLVKPFQFDELMARVRAIARRSQG 121 ++ ++ PV+ ++A+ I+ + GA DYL KPF EL+ + + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 RVVPLLTQGE-----VSVDPSSRKVTRNGKWVALS 151 R L + V + +++ R + + Sbjct: 125 RPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQT 159
>PF06580#Sensor histidine kinase Length = 349 Score = 35.6 bits (82), Expect = 2e-04 Identities = 36/206 (17%), Positives = 74/206 (35%), Gaps = 49/206 (23%) Query: 203 TLESKDAALQRLLETARRSNRLAEQLLDLARLDAGISSAAYHQVEMAELITHVLDEFSVQ 262 L + A +LE ++ + L +L R S+A QV +A+ +T V + Sbjct: 178 ALNNIRA---LILEDPTKAREMLTSLSELMRYSLRYSNA--RQVSLADELTVVDSYLQLA 232 Query: 263 AEARH---INLQVEAAPCVLRCDVDAVGILIRNLVDNAIRYG----RLHGTVEVSCGYCL 315 + + + + P ++ V +L++ LV+N I++G G + + Sbjct: 233 -SIQFEDRLQFENQINPAIMDVQVPP--MLVQTLVENGIKHGIAQLPQGGKILLK----G 285 Query: 316 RADQLHPFVQVSDDGPGVPEDARAAIFERFYRVSGNAVQGSGIGLSLVAGIARLHEARIE 375 D ++V + G ++ + + +G GL V E R++ Sbjct: 286 TKDNGTVTLEVENTGSLALKNTK---------------ESTGTGLQNV------RE-RLQ 323 Query: 376 TYEGGDGR--------GLCVRVLFPA 393 G + + + VL P Sbjct: 324 MLYGTEAQIKLSEKQGKVNAMVLIPG 349
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 82.7 bits (204), Expect = 2e-19 Identities = 31/193 (16%), Positives = 70/193 (36%), Gaps = 40/193 (20%) Query: 110 LGSGVIIDAQKGYVLTNHHVIENADDVQVTL------------GDGRTVKADFIGSDADT 157 + SGV++ K +LTN HV++ L +G + Sbjct: 103 IASGVVVG--KDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEG 160 Query: 158 DIALIRIKAD--------NLTDIKLADSNALRVGDFVVAIGNPFG---FTQTVTSGIVSA 206 D+A+++ + + ++++ +V + G P T + G ++ Sbjct: 161 DLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKPVATMWESKGKITY 220 Query: 207 VGRSGIRGLGYQNFIQTDASINPGNSGGALVNLQGQLVGINTASFNPQGSMAGNIGLGLA 266 + +Q D S GNSG + N + +++GI+ + N + + Sbjct: 221 L---------KGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHWGGVPNE----FNGAVFIN 267 Query: 267 --IPSNLARNVVE 277 + + L +N+ + Sbjct: 268 ENVRNFLKQNIED 280
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 758 bits (1960), Expect = 0.0 Identities = 245/1075 (22%), Positives = 420/1075 (39%), Gaps = 72/1075 (6%) Query: 5 IIRFAIAQRWLMLALTGVLIAIGAWSFSRLPIDATPDITNVQVQVNTAAPGYSPLESEQR 64 + F I + L +L+ GA + +LP+ P I V V+ PG + Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 65 VTFPLETVLAGLPGLESTRSLS-RYGLSQVTAVFADGTDLYFARQQVAERLQQVKSQLPP 123 VT +E + G+ L S S G +T F GTD A+ QV +LQ LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 124 ELEPQLGPIATGLGEIFMYTVEAKPNARKADGSAWTATDLRTLQDWVVRPQLRNVPGVTE 183 E++ Q + M +D T D+ V+ L + GV + Sbjct: 121 EVQQQGISVEKSSSSYLMVA------GFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGD 174 Query: 184 VNTIGGHARQIHITPDPARLVALGFTLDDVAQAVEANNRNVGAGYIER----SGQQF--L 237 V G + I D L T DV ++ N + AG + GQQ Sbjct: 175 VQLFGAQ-YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNAS 233 Query: 238 VRVPGQVDDIAQIGAIVLD-RREGVPIRVRDVAQVGEGRELRNGAATQDGTEVVLGTVFM 296 + + + + G + L +G +R++DVA+V G E N A +G + + Sbjct: 234 IIAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKL 293 Query: 297 LVGANSRTVAQAAAQRLELANASLPAGVRAVPVYDRTALVDRTIVTVAKNLIEGALLVIV 356 GAN+ A+A +L P G++ + YD T V +I V K L E +LV + Sbjct: 294 ATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFL 353 Query: 357 VLFLMLGNVRAALITAAVIPLAMLFTLTGMVRGGVSGNLMSLG--ALDFGLIVDGAVIIV 414 V++L L N+RA LI +P+ +L T + G S N +++ L GL+VD A+++V Sbjct: 354 VMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVV 413 Query: 415 ENCLRRFGEAQARLGRVLERDERFALTAEATAEVIRPSLFGVGIIAAVYLPVFALTGIEG 474 EN R E ++ T ++ +++ + +++AV++P+ G G Sbjct: 414 ENVERVMME---------DKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTG 464 Query: 475 KMFHPMAVTVVLALTGAMLLSLTFVPAAIALLLGGKVAEHE----------NRAMRWARG 524 ++ ++T+V A+ ++L++L PA A LL AEH N + Sbjct: 465 AIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVN 524 Query: 525 VYAPLLDRVLRHARWVGIGALTTVVLCAALATRLGSEFIPNLDEGDIALHAMRIPGTSLE 584 Y + ++L + V L RL S F+P D+G G + E Sbjct: 525 HYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQE 584 Query: 585 --QAISMQATLERRIKQFPEVAHVFGKLGTAEVATDPMPPSVADTFLIMHPREQWPDPRK 642 Q + Q T + V VF G + + F+ + P E+ Sbjct: 585 RTQKVLDQVTDYYLKNEKANVESVFTVNG---FSFSGQAQNAGMAFVSLKPWEERNGDEN 641 Query: 643 PKAQLVAEIEAAVRQLPGNNYEFTQPIQM-RMNELISGVRADVA-IKLYGDDLDTLVTVG 700 ++ + + ++ F P M + EL + D I G D L Sbjct: 642 SAEAVIHRAKMELGKIRDG---FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQAR 698 Query: 701 RRIEAIARSVPGA-ADVGLEQSTGLPMLAVVPDRDALAGYGLNPGVVQDTVAAAVGGQPA 759 ++ +A P + V + D++ G++ + T++ A+GG Sbjct: 699 NQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYV 758 Query: 760 GQLFDGDRRFDIVVRLPEALRQDPTALADLPIPLQGDGERNDADESSRAAGWRSGAPTTV 819 D R + V+ R P + L + +G V Sbjct: 759 NDFIDRGRVKKLYVQADAKFRMLPEDVDKLYVRS------------------ANG--EMV 798 Query: 820 PLREVARIESVLGPNQINREDGKRRIVITANVRDRDLGSFVAEVQQRVQ-AEVALPTGYW 878 P V G ++ R +G + I G+ + ++ LP G Sbjct: 799 PFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAP---GTSSGDAMALMENLASKLPAGIG 855 Query: 879 IGYGGTFEQLISAGQRLAWVVPATLLLIFALLYWSFGSLRDAVVVFSGVPLALTGGVVAL 938 + G Q +G + +V + +++F L + S V V VPL + G ++A Sbjct: 856 YDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAA 915 Query: 939 ALRGLSLSISAGVGFIALSGVAVLNGLVMIAFIRGLRDA-GMPLEQALREGALARLRPVL 997 L + VG + G++ N ++++ F + L + G + +A RLRP+L Sbjct: 916 TLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPIL 975 Query: 998 MTALVAALGFVPMAFNVGAGAEVQRPLATVVIGGIVSSTLLTLLVLPVLYRWLHR 1052 MT+L LG +P+A + GAG+ Q + V+GG+VS+TLL + +PV + + R Sbjct: 976 MTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRR 1030 Score = 81.0 bits (200), Expect = 2e-17 Identities = 86/436 (19%), Positives = 164/436 (37%), Gaps = 48/436 (11%) Query: 639 DPRKPKAQLVAEIEAAVRQLPGNNYEFTQPIQMRMNELISGVRADVAIKLYGDDLDTLVT 698 DP + Q+ +++ A LP E Q S + + D+ T Sbjct: 99 DPDIAQVQVQNKLQLATPLLPQ---EVQQQGISVEKSSSSYL---MVAGFVSDNPGTTQD 152 Query: 699 -----VGRRIEAIARSVPGAADVGLEQSTGLPMLAVVPDRDALAGYGLNPGVVQDTVAAA 753 V ++ + G DV L + + D D L Y L P V + + Sbjct: 153 DISDYVASNVKDTLSRLNGVGDVQL--FGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQ 210 Query: 754 VGGQPAGQLFDGDRRFDIVVRLPEALRQDPTALADLPIPLQGDGERNDADESSRAAGWRS 813 AGQL P Q A + + +E + + Sbjct: 211 NDQIAAGQL----------GGTPALPGQQLNAS------IIAQTRFKNPEEFGKVTLRVN 254 Query: 814 GAPTTVPLREVARIESVLGP---NQINREDGKRRIVITANVRDRDLGSFVAEVQQRVQAE 870 + V L++VAR+E LG N I R +GK + + G+ + + ++A+ Sbjct: 255 SDGSVVRLKDVARVE--LGGENYNVIARINGKPAAGLGIKLAT---GANALDTAKAIKAK 309 Query: 871 VA-----LPTGYWIGYGGTFEQLISAGQRLAWVVPATL---LLIFALLYWSFGSLRDAVV 922 +A P G + Y ++ + VV +L+F ++Y ++R ++ Sbjct: 310 LAELQPFFPQGMKVLY--PYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLI 367 Query: 923 VFSGVPLALTGGVVALALRGLSLSISAGVGFIALSGVAVLNGLVMIAFI-RGLRDAGMPL 981 VP+ L G LA G S++ G + G+ V + +V++ + R + + +P Sbjct: 368 PTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPP 427 Query: 982 EQALREGALARLRPVLMTALVAALGFVPMAFNVGAGAEVQRPLATVVIGGIVSSTLLTLL 1041 ++A + ++ A+V + F+PMAF G+ + R + ++ + S L+ L+ Sbjct: 428 KEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALI 487 Query: 1042 VLPVLYRWLHRERAPR 1057 + P L L + + Sbjct: 488 LTPALCATLLKPVSAE 503
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 36.7 bits (85), Expect = 1e-04 Identities = 29/179 (16%), Positives = 51/179 (28%), Gaps = 21/179 (11%) Query: 180 EVQGLLTPAEGGQAQATARFPGPVRSLRANVGDQVRA-GQVLATVESNLSLTTYSVSAPI 238 +++ + A+ T F + D + LA E + + AP+ Sbjct: 277 QIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASV--IRAPV 334 Query: 239 SGTVLARNA-SVGSNAGEGQALFEIA-DLSTLWVDLHIFGADAGHITAGAPVTVTRIS-- 294 S V + G + L I + TL V + D G I G + ++ Sbjct: 335 SVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAII-KVEAF 393 Query: 295 --------DGVVAQTTLERVLPGT----ATASQSTVARAVLRNTDGLW-RPGSAVKARV 340 G V L+ + S + + G AV A + Sbjct: 394 PYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEI 452
>SECA#SecA protein signature. Length = 901 Score = 33.3 bits (76), Expect = 2e-04 Identities = 10/17 (58%), Positives = 11/17 (64%) Query: 8 DPCPCGRAAGYAQCCGQ 24 DPCPCG Y QC G+ Sbjct: 883 DPCPCGSGKKYKQCHGR 899
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 37.9 bits (88), Expect = 2e-04 Identities = 20/147 (13%), Positives = 44/147 (29%), Gaps = 10/147 (6%) Query: 314 REQQRLALLEARLQEVDSQDRGLAGEEGQRRESLDNHEQKLAGLER--EQRAAGGEQIEE 371 Q + E L + ++ + + + +L ++A + E Sbjct: 197 TWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLE 256 Query: 372 LERERVRVERERDERLRRRAQIEQACRQLGTALAAGASGFAAQVAHAQGVLDGGKQHAST 431 E + V E + QIE F + +LD +Q Sbjct: 257 QENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNE------ILDKLRQTTDN 310 Query: 432 LDEAIAERMGERRDDERRFAEIRAELD 458 + E + ++ ++ + IRA + Sbjct: 311 IGLLTLEL--AKNEERQQASVIRAPVS 335 Score = 32.1 bits (73), Expect = 0.015 Identities = 35/240 (14%), Positives = 82/240 (34%), Gaps = 40/240 (16%) Query: 596 AALRNADRAITREGQVKHPGDRYEKDDRHAVNDRKRWLLGHDNRDKLKVFEREAQALAQR 655 + L + T G++ H G K+ + N + ++ + + ++ + L + Sbjct: 75 SVLGQVEIVATANGKLTHSGRS--KEIKPIENSIVKEIIVKEG-ESVR----KGDVLLKL 127 Query: 656 IAS-CDADVAALRKQREQ---DQEKRLAAHTLVERDWDEIDVGPKLQRLSDIDEQ-LQQL 710 A +AD + Q +Q + +E + KL L DE Q + Sbjct: 128 TALGAEADTLKTQSSLLQARLEQTRYQILSRSIELN--------KLPELKLPDEPYFQNV 179 Query: 711 REGDSGLRALGQAIDTARTLRDQAKRTYEDVRLERAQLARERVRLEQQQAACAGRAGTAA 770 E + + +L + T+ + Q ++ + L++++A Sbjct: 180 SEEE---------VLRLTSLIKEQFSTW------QNQKYQKELNLDKKRAERLTVLARIN 224 Query: 771 LTPTQLQGLQERLAALAPLSLDTLEAHFRVV--ERGLAE---QLAESQGRDSRLSAQLLE 825 + + RL + L A V+ E E +L + + ++ +++L Sbjct: 225 RYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILS 284
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 49.8 bits (119), Expect = 5e-09 Identities = 19/142 (13%), Positives = 50/142 (35%), Gaps = 2/142 (1%) Query: 86 ALEQARAALAERQATLTQLRREIARDRSLQDLVAAEDAEVRRSNVQKAQAAVATAQSAVD 145 +A L ++ L Q+ EI + LV +++ + + Sbjct: 260 KYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELA 319 Query: 146 LAQLNLDRTEVRSPADGHISDRTVR-VGDYVSAGRPVVAVL-DTGSFRVDGYFEETRLQG 203 + + +R+P + V G V+ ++ ++ + + V + + Sbjct: 320 KNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGF 379 Query: 204 VHPGQRVDVHLMGEPVTLHGHV 225 ++ GQ + + P T +G++ Sbjct: 380 INVGQNAIIKVEAFPYTRYGYL 401 Score = 42.5 bits (100), Expect = 1e-06 Identities = 21/168 (12%), Positives = 58/168 (34%), Gaps = 19/168 (11%) Query: 10 PALLTLAMVVVAAVVLQHLWRYYMDAPWTRDAHVGADVV------QVAPDVSGLVEQVAV 63 +A ++ +V+ + A + ++ P + +V+++ V Sbjct: 55 RRPRLVAYFIMGFLVIAFILSVL--GQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIV 112 Query: 64 ADNQAVTRGQLLFVVDRARYAIALEQARAALAERQATLTQLRREIARD----RSLQDLVA 119 + ++V +G +L + + +++L QA L Q R +I L +L Sbjct: 113 KEGESVRKGDVLLKLTALGAEADTLKTQSSLL--QARLEQTRYQILSRSIELNKLPELKL 170 Query: 120 AEDAEVRRSNVQKAQAAVATAQSAVD-----LAQLNLDRTEVRSPADG 162 ++ + + ++ + + Q L+ + R+ Sbjct: 171 PDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLT 218
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.2 bits (68), Expect = 0.021 Identities = 14/117 (11%), Positives = 36/117 (30%), Gaps = 5/117 (4%) Query: 357 TLPSSGAHARVRATEAGADAAVAQFDHTVLQA-LREVQTTLSRYAQDLDRLRLLEQA-QQ 414 LP V E ++ + + Q + + L + + + + Sbjct: 169 KLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYEN 228 Query: 415 QAELASSQN---RRLYQGGRTPYLSSLDAERTLATADMTLADAQAQVSKDQIQLFLA 468 + + S+ L + L+ E A L ++Q+ + + ++ A Sbjct: 229 LSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSA 285
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 35.6 bits (82), Expect = 3e-04 Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 14/86 (16%) Query: 69 AIFA-MTFLMRPIGAWYFGRFADRYGRRLALTISVSMMALCSFVIAITPTVSTIGIAAPI 127 A++A M F P+ G +DR+GRR L +S++ A+ ++A P + Sbjct: 50 ALYALMQFACAPVL----GALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLW-------- 97 Query: 128 ILLLARLLQGFATGGEYGTSATYMSE 153 +L + R++ G TG + Y+++ Sbjct: 98 VLYIGRIVAGI-TGATGAVAGAYIAD 122
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 77.0 bits (189), Expect = 1e-18 Identities = 43/187 (22%), Positives = 83/187 (44%), Gaps = 3/187 (1%) Query: 6 LITGASSGFGRGLTQTLLARGDRVAA---TVRRADALADLQAAHGNALTVLQLDVRDTAA 62 ITGA+ G G + +TL ++G +AA + + + A DVRD+AA Sbjct: 12 FITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSAA 71 Query: 63 VQAVVAQAFAALGRIDVVISNAGYGTLGAAEAATDAQVRALIDTNLIGSISVIQAALPHL 122 + + A+ +G ID++++ AG G + +D + A N G + ++ ++ Sbjct: 72 IDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSKYM 131 Query: 123 RRQGGGHVVQVSSEGGQIAYPGFSLYHASKWGIEGYVEAVRQEVAGFGIQFTLAEPGPAR 182 + G +V V S + + Y +SK + + + E+A + I+ + PG Sbjct: 132 MDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGSTE 191 Query: 183 TNFGAAL 189 T+ +L Sbjct: 192 TDMQWSL 198
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 30.4 bits (68), Expect = 0.004 Identities = 30/138 (21%), Positives = 49/138 (35%), Gaps = 18/138 (13%) Query: 32 RQPWKPVAATLRTALLLVATAALGYAAYG----LPGVAPGVALGAVVGAGLGVVSLRYTH 87 R+ +P+ + L+ T +AA+ +P + G+A GA VG G++ Sbjct: 8 RKINRPLVSLALVGALVSITPQQSHAAFFTTVIIPAIVGGIATGAAVGTVSGLLGWGLKQ 67 Query: 88 AEWVDGRGWYTPNPWIGGALMLV---------LLGRLAWRWTDGAFSGGAA-----VAGS 133 AE + W A L L DG + G A V Sbjct: 68 AEEANKTPDKPDKVWRIQAGKGFNEFPNKEYDLYKSLLSSKIDGGWDWGNAARHYWVKDG 127 Query: 134 QASPLTLGIAAALVLYSL 151 Q + L + + A+ Y+L Sbjct: 128 QWNKLEVDMQNAVGTYNL 145
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 35.5 bits (81), Expect = 3e-04 Identities = 33/117 (28%), Positives = 44/117 (37%), Gaps = 6/117 (5%) Query: 132 PPQGSASGGRTKVDFVGDTSQPDQPVPSPTPVPPSPTPTPVQPPPAASPVQSTLVQQAKN 191 P Q A+ GR D G+T+ Q +P P P S QP P SP ++ A N Sbjct: 288 PVQVVATFGR---DSQGNTTVDVQVIPRPDLTPGSAEAPNAQPLPEVSPAENPANNPAPN 344 Query: 192 PVP---PQGDTAPGSLAERRRQTRRQTRPTPPQPPAPPAASTQRRPETWTGRPPGML 245 P P + P + T Q P P P + + R E G G+L Sbjct: 345 ENPGTRPNPEPDPDLNPDANPDTDGQPGTRPDSPAVPDRPNGRHRKERKEGEDGGLL 401
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 31.7 bits (71), Expect = 0.007 Identities = 18/64 (28%), Positives = 31/64 (48%) Query: 382 NVFVVQGALDNPAHLMAHMKTSDAIAQPVEQSLSQLQTLSETQRQQQAQQQSQQQDQQQL 441 N+ + A+ NP +L + S+ I Q E L Q++ L + Q Q QA Q ++ + Sbjct: 179 NLENLTNAMSNPQNLSNNKNLSELIKQQRENELDQMERLEDMQEQAQANALKQIEELNKK 238 Query: 442 SAPQ 445 A + Sbjct: 239 QAEE 242
>INTIMIN#Intimin signature. Length = 939 Score = 35.8 bits (82), Expect = 0.002 Identities = 73/389 (18%), Positives = 118/389 (30%), Gaps = 52/389 (13%) Query: 236 QGQGTIVNDDALPSLSIDDVSVNEGNSGTTTATFTVTL--SAASGQTVSVNYASADGTAT 293 G +V+ + + D S + T T TV A + VS N S + Sbjct: 549 LSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKNGVAQANVPVSFNIVSGTAVLS 608 Query: 294 AGSDYVARSGTLTFAPGTTAQGVAI----TVNGDTALEPNETFSVGLSGASNASI----- 344 A S SG T + G + T +AL N V + AS I Sbjct: 609 ANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQTKASITEIKADKT 668 Query: 345 -ARATGAGTILNDDVVVTVGPASLPAATAGSAYSQNLSASGGTAPYSFAVTAGALPAGLT 403 A A G I V V P + ++ L + + G LT Sbjct: 669 TAVANGQDAI---TYTVKVMKGDKPVSNQEVTFTTTLGKLSNSTEKTDT--NGYAKVTLT 723 Query: 404 LSAAGVLSGTPTATG-SFNFTATATDSGGSPTSGNRAYTLTVAGATVTLPATSLPAGTAG 462 + G + + + + A + + T + + G LP L G Sbjct: 724 STTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGTGVKGKLPTVWLQYGQVN 783 Query: 463 QAYSGALNPATGGIPPYTYAVTAGALPAGITLNGSSGALTGTPGSVGSFAFSVTATDSTS 522 A+GG YT+ A+ +++ SSG + T G+ SV ++D+ + Sbjct: 784 L-------KASGGNGKYTWRSANPAIA---SVDASSGQV--TLKEKGTTTISVISSDNQT 831 Query: 523 GTPSQGTRGYTLNIAAPPIVVAPSTLPAATRGTAYSQTLSAS---------------GGT 567 T YT+ IV S + G Sbjct: 832 AT-------YTIATPNSLIVPNMSKRVTYNDAVNTCKNFGGKLPSSQNELENVFKAWGAA 884 Query: 568 APYTYALASGALPAGLTLASNGTLSGTAT 596 Y Y +S + + + + SG A+ Sbjct: 885 NKYEYYKSSQTIISWVQQTAQDAKSGVAS 913 Score = 33.5 bits (76), Expect = 0.011 Identities = 70/402 (17%), Positives = 116/402 (28%), Gaps = 54/402 (13%) Query: 547 TLPAATRGTAYSQTLSASG----GTAPYTYALASGALPAGLTLASNGTLSGTATVEGS-- 600 LPA +G + ++A G + L L G + G TA + Sbjct: 513 ILPAYVQGGSNVYKVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKA 572 Query: 601 -----FNFTVTATDAGSFTANQAYSLTVAGPNLVLPASSLPAGTAGQAYSASITPATGGT 655 +T T G AN S + +G A ++ + T G+ Sbjct: 573 DGTEAITYTATVKKNGVAQANVPVSFNI---------------VSGTAVLSANSANTNGS 617 Query: 656 APYSYALTAGALPTGVVVDVATGGLSGTPTVAGTFNFTLTVSDSTPSPAAQASRSYTLTI 715 + L + VV S A F S + + + Sbjct: 618 GKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQTKASITEIKADKTTAVANGQDA 677 Query: 716 AAPVIVVAPTALPAATRGTVYSQTLSASGGTAPYTYAVSAGNVPAGLTLASNGTLSGTAT 775 + V P + + ++ TL + T G LT + G +A Sbjct: 678 ITYTVKVMKGDKPVSNQEVTFTTTLGKLSNSTEKTDT--NGYAKVTLTSTTPGKSLVSAR 735 Query: 776 VEGSFNFTVTATDANTFTAS--QAYAVTVAGPNL--ALPASSLPAGTAGQAYAATIAPAT 831 V V A + FT + + G + LP L G A+ Sbjct: 736 VSDV-AVDVKAPEVEFFTTLTIDDGNIEIVGTGVKGKLPTVWLQYGQVNL-------KAS 787 Query: 832 GGTAPYSYALSAGVLPNGVVLDTATGGLSGMPTLSGTFNFTLTVTDSTPSPAAQASQSYT 891 GG Y++ + + + SG TL T++V S +Q+ T Sbjct: 788 GGNGKYTWRSANPAI-------ASVDASSGQVTLKEKGTTTISVISSD-------NQTAT 833 Query: 892 LSIAAPVIVVAPTALPAATRGTAYSQVLTASGGTAPYTYEVN 933 +IA P ++ P T A + G E+ Sbjct: 834 YTIATPNSLIVPNMSKRVTYNDAVNTCKNFGGKLPSSQNELE 875
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 44.6 bits (105), Expect = 3e-08 Identities = 28/124 (22%), Positives = 51/124 (41%), Gaps = 23/124 (18%) Query: 59 YRQHYRDADFLI------------VQTPDERIGRLYLQRAAVQHVLV-DISLLPHWRGRG 105 Y + Y D D + + IGR+ ++ + L+ DI++ +R +G Sbjct: 46 YFKQYEDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKG 105 Query: 106 VGTALIMHAQALAQAAG-CGVALHVFHANPAARRLYTRLGFL---------AGDASSTHL 155 VGTAL+ A A+ CG+ L N +A Y + F+ + ++ + Sbjct: 106 VGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGAVDTMLYSNFPTANEI 165 Query: 156 AMHW 159 A+ W Sbjct: 166 AIFW 169
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 27.9 bits (62), Expect = 0.047 Identities = 22/117 (18%), Positives = 40/117 (34%), Gaps = 21/117 (17%) Query: 7 PVVQLSGVRIDRGGRAILRDVS-----------------LDVPRGSITAVLGPSGSGKST 49 V +GVR D G A+L + +D+ V G+ Sbjct: 730 KVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPT-RGAIVRA 788 Query: 50 LLAALTGELRPVAGRVTLFGQEIPRGSRALLEMRRNVGVLLQ-GNGLLTDLSVADNV 105 A G + +T + +P G+ E ++ G++ G L+ + +A V Sbjct: 789 EFKARVG--IKLLMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKV 843
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 235 bits (602), Expect = 8e-79 Identities = 76/216 (35%), Positives = 104/216 (48%), Gaps = 13/216 (6%) Query: 108 GGAAAGPALPGGAPAYDPWERYNRGMHRFNLAV-DRGVARPLATGYTKVVPRPARLGVTN 166 G A+ G DP E +NR M+ FN V D + RP+A + VP+PAR G++N Sbjct: 16 VGCASSGTDQQGR--SDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWRDYVPQPARNGLSN 73 Query: 167 FFDNLGSPLTMVNQLLQGHPVYAVQTLGRFVMNSTLGVAGLFDPASAAGIPRR---SEDF 223 F NL P MVN LQG P + RF +N+ LG+ G D A A + F Sbjct: 74 FTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGMANPKLQRTEPHRF 133 Query: 224 GQTLGVWGWRNSRYFELPLFGPRTVRDTLGLGGDI---PLSWVRQVNDGGARFALQGLQL 280 G TLG +G Y +LP +G T+RD G D LSW L+ Sbjct: 134 GSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMADALYPVLSW----LTWPMSVGKWTLEG 189 Query: 281 VDTRAQLMSLDSLRDQAPDEYALTRDAWMQRRNYQI 316 ++TRAQL+ D L Q+ D Y + R+A+ QR ++ Sbjct: 190 IETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIA 225
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.8 bits (67), Expect = 0.018 Identities = 11/49 (22%), Positives = 21/49 (42%), Gaps = 3/49 (6%) Query: 308 PLQALLTQDRRSQLLQTLSCWFANGMRMTPTAKALGIHRNTLDYRMQRI 356 +L + +L L+ A A LG++RNTL +++ + Sbjct: 428 LYDRVLAEMEYPLILAALT---ATRGNQIKAADLLGLNRNTLRKKIREL 473
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 28.5 bits (63), Expect = 0.040 Identities = 13/47 (27%), Positives = 23/47 (48%), Gaps = 2/47 (4%) Query: 268 TPAKKTTAAADTAPAKKTATKKAAKKATKKTA--TKATKKAAPRRKA 312 TP++ T A+ + + +K + AT+ TA + K+A KA Sbjct: 1032 TPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKA 1078
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 33.5 bits (76), Expect = 0.006 Identities = 36/225 (16%), Positives = 64/225 (28%), Gaps = 10/225 (4%) Query: 530 RQAAFKRLREDKPMSDLGGDR--ATPGKSRGARTRTAAAAAGKASRAAATRTAAVSAGGS 587 +++ E +R A KS A S T+T + Sbjct: 1046 QESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETAT 1105 Query: 588 AAKPGKAGKSSTAADVSTPSRVA----KQRVTPAASSAAKPGKPGKSSAAATGTASPRAA 643 K KA K T P + KQ + A+P + + S Sbjct: 1106 VEKEEKA-KVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQT-- 1162 Query: 644 KRGAVSTASASSTPKSGKRSVSSGSAASGKPAAPSKAASSKTARTPATSSARKTSTATAA 703 A + A T + ++ V+ + + + ++ A T T ++ ++S Sbjct: 1163 NTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNS-ESSNKPKN 1221 Query: 704 SSIRKARASASNAPDGVAITHPERVVFPAAGISKGDVAAYYRAVA 748 R R+ N ++ V S A A A Sbjct: 1222 RHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARA 1266
>PF06580#Sensor histidine kinase Length = 349 Score = 41.8 bits (98), Expect = 3e-06 Identities = 68/370 (18%), Positives = 133/370 (35%), Gaps = 79/370 (21%) Query: 79 WRWATVIGFTALFLFRALLPPRPLPQHAAL-------LLQALLAVALIWLEPRTGTSPVL 131 W T+ GF L+ + P+ ++ L+ +L A R Sbjct: 20 WGVYTLTGFGFASLYGS-------PKLHSMIFNIAISLMGLVLTHAYRSFIKR----QGW 68 Query: 132 LVLVAAQAAMRWPPPQVL--ALMLVLNAAMYAVFVLAGV-PRPFLM-------VAIYTSF 181 L L Q +R P V+ + V N +++ + P F + + Sbjct: 69 LKLNMGQIILRVLPACVVIGMVWFVANTSIWRLLAFINTKPVAFTLPLALSIIFNVVVVT 128 Query: 182 QAFAALT--ANYARSAERARDALVYVNADLLATRALLADSARDAERLRLARELHDVAGH- 238 ++ L ++ ++ ++A +A A++A+ + L +++ H Sbjct: 129 FMWSLLYFGWHFFKNYKQAEIDQWK-----------MASMAQEAQLMALKAQINP---HF 174 Query: 239 ---KLTAMRIHLRLLRAEPALAPREDLRMLEQLSGEL---LGDIRSVVQSLRDDAGLDLH 292 L +R L+ +P A ML LS + L + SL D+ L + Sbjct: 175 MFNALNNIR---ALILEDPTKA----REMLTSLSELMRYSLRYSNARQVSLADE--LTVV 225 Query: 293 TA-LHALAAPFPRPALRLQIDAQVRVSDPQVAEALVR--LVQEALTNAARHG-----DAD 344 + L + F RLQ + Q+ +P + + V LVQ + N +HG Sbjct: 226 DSYLQLASIQFED---RLQFENQI---NPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGG 279 Query: 345 TVTVAVRCDAGALCVDIQDDGR-CAEQIHEGNGI--AGMRERLAALSG-QLDLR-RAAHG 399 + + D G + +++++ G + E G +RERL L G + ++ G Sbjct: 280 KILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQG 339 Query: 400 GLHLTARLPA 409 ++ +P Sbjct: 340 KVNAMVLIPG 349
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 85.3 bits (211), Expect = 1e-21 Identities = 30/118 (25%), Positives = 53/118 (44%), Gaps = 1/118 (0%) Query: 1 MSALRIALADDQVLVRAALRALLQQQGITVVCEADDGQALLDALATHNVDVVLSDIRMPG 60 M+ I +ADD +R L L + G V + L +A + D+V++D+ MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPD 59 Query: 61 LDGIAALEQLRARGDRTPVLLLTTFDDSELLLRACEAGAQGFLLKDAAPDDLHEAIAR 118 + L +++ PVL+++ + ++A E GA +L K +L I R Sbjct: 60 ENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>SURFACELAYER#Lactobacillus surface layer protein signature. Length = 439 Score = 27.3 bits (60), Expect = 0.024 Identities = 15/45 (33%), Positives = 26/45 (57%) Query: 5 ASIAVTAALCACALPALASETLNSRTDVLAALEAGYDVSVSTDLS 49 A++ A + A A+P A+ T+N+ + + A A YDV V+ +S Sbjct: 13 AALLAVAPIAATAMPVNAATTINADSAINANTNAKYDVDVTPSIS 57
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 60.8 bits (147), Expect = 1e-13 Identities = 28/194 (14%), Positives = 60/194 (30%), Gaps = 6/194 (3%) Query: 18 DVRDQIVNAATEHFRRYGYEKTAVSDLAKSIGFSKAYIYKFFESKQAIGEMICTNCLRQI 77 + R I++ A F + G T++ ++AK+ G ++ IY F+ K + I I Sbjct: 11 ETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNI 70 Query: 78 -EDEVRAAVDETDSPPEKFRRMFKVIVDASL-----RLFFEDRKLYEIAASAATERWQSV 131 E E+ P R + ++++++ RL E Q+ Sbjct: 71 GELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQ 130 Query: 132 LAYEERVLALLQEILQQGRQGGDFERKTPLDEATRALYVLIRPYTNPVLMQHSLDVIDEV 191 +++ L+ + A + I L + + Sbjct: 131 RNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLKKE 190 Query: 192 PGLLSGLVLRSLSP 205 ++L Sbjct: 191 ARDYVAILLEMYLL 204
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 43.7 bits (103), Expect = 8e-07 Identities = 18/104 (17%), Positives = 35/104 (33%), Gaps = 7/104 (6%) Query: 68 VSGKVSERLVDAGQRVTRGQPLLRIDPVD-----LKLAAQAQQEAVTAARARA--QQAGE 120 + V E +V G+ V +G LL++ + LK + Q + R + + Sbjct: 103 ENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIEL 162 Query: 121 DEARYRDLRGTGAISASAYDQIKAAADAAKAQLSAAQAQADVAR 164 ++ L + +++ K Q S Q Q Sbjct: 163 NKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKE 206 Score = 33.6 bits (77), Expect = 0.001 Identities = 11/112 (9%), Positives = 31/112 (27%), Gaps = 5/112 (4%) Query: 88 PLLRIDPVDLKLAAQAQQEAVTAARARAQQAGEDEARYRDLRGTGAISASAYDQIKAAAD 147 + + K + V ++ ++ A+ T D+++ Sbjct: 250 AKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQT-- 307 Query: 148 AAKAQLSAAQAQADVARNANRYTDLLADADGVVMETLV-EPGQVVAAGQPVV 198 + + + + + A V + V G VV + ++ Sbjct: 308 --TDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLM 357 Score = 30.6 bits (69), Expect = 0.012 Identities = 15/84 (17%), Positives = 29/84 (34%), Gaps = 2/84 (2%) Query: 178 GVVMETLVEPGQVVAAGQPVVRLAHAGRREAIIQLPETLQPVVGSTAQATLFGNAGVTEP 237 +V E +V+ G+ V G +++L G ++ +L Q + E Sbjct: 105 SIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLL--QARLEQTRYQILSRSIEL 162 Query: 238 ATLRQLSDSADRLTRTFEARYVLG 261 L +L + + VL Sbjct: 163 NKLPELKLPDEPYFQNVSEEEVLR 186
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 438 bits (1127), Expect = e-139 Identities = 230/1047 (21%), Positives = 434/1047 (41%), Gaps = 63/1047 (6%) Query: 8 LSALAVRERSITLFLIVLISLAGLVAFLKLGRAEDPAFTVKVMTIITAWPGATPQEMQEQ 67 ++ +R L +++ +AG +A L+L A+ P +++ +PGA Q +Q+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 68 VAEKLEKRMQELRWYDRTETYT-RPGLAFTTLTLLDSTPP----GEVQEQFYQARKKVGD 122 V + +E+ M + + + G TLT T P +VQ + A Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPL--- 117 Query: 123 EAGNLPAGVIGPMVNDEYADVTFAL---FALKAKGEPQRLLARDAE-TMRQRLLHVPGVK 178 LP V ++ E + ++ + F G Q ++ ++ L + GV Sbjct: 118 ----LPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVG 173 Query: 179 KVNIIGEQPERIFVEFSHDRLATLGVSPQDVFAALNAQNALTAAGSVETRGP------DV 232 V + G Q + + D L ++P DV L QN AAG + + Sbjct: 174 DVQLFGAQ-YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNA 232 Query: 233 FIRLDGALDNLQKIRDTPLVVQ--GRSLKLSDIATVKRGYEDPSTFMIRSGGEPALLLGI 290 I N ++ L V G ++L D+A V+ G E+ + R G+PA LGI Sbjct: 233 SIIAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVI-ARINGKPAAGLGI 291 Query: 291 IMRDGWNGLDLGKSLDAEVGAINAELPLGMQLSKVTDQAVNIDASVGEFMTKFFVALLVV 350 + G N LD K++ A++ + P GM++ D + S+ E + F A+++V Sbjct: 292 KLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLV 351 Query: 351 MLVCFVSMG-WRVGIVVAAAVPLTLAAVFVVMLATGKNFDRITLGSLILALGLLVDDAII 409 LV ++ + R ++ AVP+ L F ++ A G + + +T+ ++LA+GLLVDDAI+ Sbjct: 352 FLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIV 411 Query: 410 AIEMMV-VKMEEGYGRVAASAYAWSHTAAPMLSGTLVTAVGFMPNGFAASTAGEYTSNMF 468 +E + V ME+ A+ + S ++ +V + F+P F + G Sbjct: 412 VVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFS 471 Query: 469 WIVGIALIVSWAVAVVFTPYLGVKML----PDMKKIEGGHAAIYNT---PRYNRFRQALG 521 + A+ +S VA++ TP L +L + + +GG +NT N + ++G Sbjct: 472 ITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVG 531 Query: 522 RVIARKWLVAGSVVGLFVLAVVGMGIVKKQFFPISDRPEVLVEVQLPYGTSINQTSTAAA 581 +++ + VV + F P D+ L +QLP G + +T Sbjct: 532 KILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLD 591 Query: 582 KVEAWLSKQKEAKIVTAYIGQGAPRFFLAMGPELPDPSFAKIVV-----RTDDQHERDAL 636 +V + K ++A + + + G + + + A + + R D++ +A+ Sbjct: 592 QVTDYYLKNEKANVESVFTVNG-----FSFSGQAQNAGMAFVSLKPWEERNGDENSAEAV 646 Query: 637 KLRLREAIAQGLAPEARVRA----TQLTFGPYSKFPVA-YRVSGPDPTVLRGIAAQVMQV 691 R + + + + V + G + F +G L Q++ + Sbjct: 647 IHRAKMELGK--IRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGM 704 Query: 692 MQDSP-MLRTVNTDWGVRTPTLHFSLDQDRLQAVGLTSAAVAQQLQFLLSGVPITLVRED 750 P L +V + T +DQ++ QA+G++ + + Q + L G + + Sbjct: 705 AAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDR 764 Query: 751 IRSVQVVARSAGDTRLDPARIADFTLAGGNGQRVPLSQVGKVDVRMEEPVMRRRDRVPTI 810 R ++ ++ R+ P + + NG+ VP S P + R + +P++ Sbjct: 765 GRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSM 824 Query: 811 TVGGDVDDTLQPPDVSAAITRQLQPIIDKLPSGYQIKEAGSIEESGKATAAMLPLFPIML 870 + G+ P S ++ + KLP+G G + + L I Sbjct: 825 EIQGEA----APGTSSGDAMALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISF 880 Query: 871 AATLLIIILQVRSISAMVMVFLTSPLGLIGVVPTLILFQQPFGINALVGLIALSGILMRN 930 L + S S V V L PLG++GV+ LF Q + +VGL+ G+ +N Sbjct: 881 VVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKN 940 Query: 931 TLILIGQIHH-NEAEGLDPFHALVGATVQRARPVILTALAAILAFIPLTHSVFWGT---- 985 ++++ E EG A + A R RP+++T+LA IL +PL S G+ Sbjct: 941 AILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQN 1000 Query: 986 -LAYTLIGGTLAGTVLTLVFLPAMYSI 1011 + ++GG ++ T+L + F+P + + Sbjct: 1001 AVGIGVMGGMVSATLLAIFFVPVFFVV 1027 Score = 71.4 bits (175), Expect = 1e-14 Identities = 59/330 (17%), Positives = 122/330 (36%), Gaps = 24/330 (7%) Query: 712 LHFSLDQDRLQAVGLTSA----AVAQQLQFLLSGVPITLVREDIRSVQVVARSAGDTRLD 767 + LD D L LT + Q + +G + + + + + Sbjct: 184 MRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK-N 242 Query: 768 PARIADFTL-AGGNGQRVPLSQVGKVDVRMEE-PVMRRRDRVPTITVGGDVDDTLQPPDV 825 P TL +G V L V +V++ E V+ R + P +G + D Sbjct: 243 PEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDT 302 Query: 826 SAAITRQLQPIIDKLPSGYQIKEA----GSIEESGKATAAMLPLFPIMLAATLLIIILQV 881 + AI +L + P G ++ ++ S L IML L++ L + Sbjct: 303 AKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTL-FEAIMLVF--LVMYLFL 359 Query: 882 RSISAMVMVFLTSPLGLIGVVPTLILFQQPFGINA--LVGLIALSGILMRNTLILIGQIH 939 +++ A ++ + P+ L+G IL + IN + G++ G+L+ + ++++ + Sbjct: 360 QNMRATLIPTIAVPVVLLGTF--AILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVE 417 Query: 940 -HNEAEGLDPFHALVGATVQRARPVILTALAAILAFIPL-----THSVFWGTLAYTLIGG 993 + L P A + Q ++ A+ FIP+ + + + T++ Sbjct: 418 RVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSA 477 Query: 994 TLAGTVLTLVFLPAMYSIWFKIRPDPGKGN 1023 ++ L+ PA+ + K N Sbjct: 478 MALSVLVALILTPALCATLLKPVSAEHHEN 507
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 102 bits (256), Expect = 3e-28 Identities = 56/185 (30%), Positives = 82/185 (44%), Gaps = 8/185 (4%) Query: 6 VVLITGVSSGIGRAAAEHFARAGCLVYGSVRHLAGATPLTAVELVE--------MDIRDA 57 + ITG + GIG A A A G + + + + E D+RD+ Sbjct: 10 IAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDS 69 Query: 58 ASVQRAVDGIIARAGRIDVLVNNAGTNLVGAIEETSVDEAAALFDINLLGILRTVQAVLP 117 A++ I G ID+LVN AG G I S +E A F +N G+ ++V Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSK 129 Query: 118 HMRARGQGRIVNVSSVLGFLPAPYMGVYAASKHAVEGLSETLDHELRQFGIRVTLVEPAY 177 +M R G IV V S +P M YA+SK A ++ L EL ++ IR +V P Sbjct: 130 YMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGS 189 Query: 178 TKTSL 182 T+T + Sbjct: 190 TETDM 194
>SECA#SecA protein signature. Length = 901 Score = 30.2 bits (68), Expect = 0.019 Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 6/66 (9%) Query: 252 LLVFVTSRHGADKVAEKLSKTGIAALPLHGELSQGRRERTLRAFKQADVQ--VLVATDLA 309 +LV S ++ V+ +L+K GI H L+ QA V +AT++A Sbjct: 452 VLVGTISIEKSELVSNELTKAGIK----HNVLNAKFHANEAAIVAQAGYPAAVTIATNMA 507 Query: 310 GRGIDI 315 GRG DI Sbjct: 508 GRGTDI 513
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 40.0 bits (93), Expect = 5e-06 Identities = 21/79 (26%), Positives = 30/79 (37%), Gaps = 1/79 (1%) Query: 55 EAGLQQAQRAQAAQRRQIEQLQQRQVNLAMSDKISRAANTEVQASLAERDEQIAALRADV 114 A Q +R A R +QL+ L +KIS A+ ++ L E L A+ Sbjct: 308 NANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEH 367 Query: 115 AFYERLVG-STAQRKGLNA 132 E S A R+ L Sbjct: 368 QKLEEQNKISEASRQSLRR 386
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 52.5 bits (126), Expect = 5e-11 Identities = 25/124 (20%), Positives = 51/124 (41%), Gaps = 14/124 (11%) Query: 1 MTAIRTILLAEDSPADAEMAVDALRDARLANPIVHVEDGVETMDYLLRRGAFANREEGLP 60 MT IL+A+D A + AL A + + ++ G Sbjct: 1 MTGAT-ILVADDDAAIRTVLNQALSRAGY--DVRITSNAATLWRWI---------AAGDG 48 Query: 61 AVLLLDIKMPRLDGLEVLKQIRNEESLKRLPVVILSSSREESDLARSWDLGVNAYVVKPV 120 +++ D+ MP + ++L +I+ LPV+++S+ ++ + G Y+ KP Sbjct: 49 DLVVTDVVMPDENAFDLLPRIKKAR--PDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPF 106 Query: 121 DVDQ 124 D+ + Sbjct: 107 DLTE 110
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 69.9 bits (171), Expect = 6e-15 Identities = 35/147 (23%), Positives = 63/147 (42%), Gaps = 4/147 (2%) Query: 12 KILLVEDSPEDAELLSDQLLDAGIDAAFERVDSEPSLRAAMERFQPDIVLSDLSMPGFSG 71 IL+ +D +L+ L AG D + +L + D+V++D+ MP + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDV--RITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 72 HQALRLVRQSGA-TPFIFVSGTMGEETAVKALQDGANDYIIKH-NPTRLPSAVLRAIREA 129 L ++++ P + +S TA+KA + GA DY+ K + T L + RA+ E Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 130 RAEIERQRVESELMRAQRLESLAMLAA 156 + + +S+ S AM Sbjct: 123 KRRPSKLEDDSQDGMPLVGRSAAMQEI 149 Score = 41.7 bits (98), Expect = 5e-06 Identities = 27/126 (21%), Positives = 53/126 (42%), Gaps = 15/126 (11%) Query: 380 GQRILLVDGEATRLSLLGNALSSQGYQPQLATDGAAALQLVQQHAMPDLVIIDSDIILLS 439 G IL+ D +A ++L ALS GY ++ ++ A + + DLV+ D + + Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGD-GDLVVTDVVMPDEN 61 Query: 440 AVSVLLSMQELGYQGPAIVLED-------VGAPLQRAHLPHDIPVHVLRKPLEMRRVFRA 492 A +L +++ P +V+ + A + A+ L KP ++ + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAY-------DYLPKPFDLTELIGI 114 Query: 493 VAHALE 498 + AL Sbjct: 115 IGRALA 120
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 102 bits (256), Expect = 2e-28 Identities = 68/257 (26%), Positives = 116/257 (45%), Gaps = 19/257 (7%) Query: 4 RIAYVTSGMGSVGTAICQKLARTGHTVVAGCGPNSPRKSAWLREQRELGFDFVASEGNAA 63 +IA++T +G A+ + LA G +A N + + + A + Sbjct: 9 KIAFITGAAQGIGEAVARTLASQG-AHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVR 67 Query: 64 DWDSTMAAFAKVKAEVGEIDVLVNNAGGSRDTLFRQMSRDDWNAVIASNLHSLFNITKQV 123 D + A+++ E+G ID+LVN AG R L +S ++W A + N +FN ++ V Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 124 VDGMTSRGWGRIVNIGSVSAHKGQIGQINFATAKAAMHGFSRALAQEVASRGVTVNTISP 183 M R G IV +GS A + +A++KAA F++ L E+A + N +SP Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 184 G--------------YIASASISNFPPDVLDRLATSVPVRRLGKPAEVAGLCAWLASDDA 229 G A I L+ T +P+++L KP+++A +L S A Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGS----LETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 230 AYVTGADYAVNGGLYMG 246 ++T + V+GG +G Sbjct: 244 GHITMHNLCVDGGATLG 260
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 76.8 bits (189), Expect = 2e-18 Identities = 31/123 (25%), Positives = 59/123 (47%), Gaps = 1/123 (0%) Query: 2 RLLLVEDNADLADAIVRRMRRSGHAVDWQQDGLAAASVLRYQSFDLVVLDIGLPKLDGLR 61 +L+ +D+A + + + + R+G+ V + + DLVV D+ +P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VLAGMRERGDTTPVLMLTARDGIEDRVQALDVGADDYLGKPFDFREF-EARCRVLLRRNR 120 +L +++ PVL+++A++ ++A + GA DYL KPFD E R L R Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 121 GQA 123 + Sbjct: 125 RPS 127
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.7 bits (72), Expect = 0.004 Identities = 15/107 (14%), Positives = 29/107 (27%), Gaps = 12/107 (11%) Query: 49 AVIQDYQRLHPGTEVI----YEDVIAWDIYEQYLHPAANAPQADLLISASMDLQTKLVND 104 ++ ++ P V+ + A+ A + DL + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTA--------IKASEKGAYDYLPKPFDLTELIGII 115 Query: 105 GHALTHRSAQTEALPAWAQWRHEVFGISYEPVAIVYNTRKLAAARVP 151 G AL + L +Q + G S I +L + Sbjct: 116 GRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLT 162
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 61.0 bits (148), Expect = 3e-13 Identities = 33/108 (30%), Positives = 53/108 (49%), Gaps = 3/108 (2%) Query: 1 MADLTILVADDHPLFRAAVIHVLHQTLPTAEVVEASSATTLSAMLRSHPQAELVLLDLAM 60 M TILVADD R + L + +V S+A TL + + +LV+ D+ M Sbjct: 1 MTGATILVADDDAAIRTVLNQAL--SRAGYDVRITSNAATLWRWIAAGDG-DLVVTDVVM 57 Query: 61 PGARGFSALLHVRGEHPDIPVVVISSNDHPRVIRRAQQFGAAGFIPKS 108 P F L ++ PD+PV+V+S+ + +A + GA ++PK Sbjct: 58 PDENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKP 105
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 62.2 bits (151), Expect = 5e-12 Identities = 24/120 (20%), Positives = 44/120 (36%), Gaps = 3/120 (2%) Query: 762 RVWCVDDDPRVCEATRALLERWECRVDFAGGPDDALAAASPDDAPELLLLDVRMGNHYGP 821 + DDD + L R V + +L++ DV M + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIA-AGDGDLVVTDVVMPDENAF 63 Query: 822 MLLPQLVAQWQREPRVILVTAEPSPALREHALEAG-WGFLSKPVRPPALRALVTQMLLRR 880 LLP++ P V++++A+ + A E G + +L KP L ++ + L Sbjct: 64 DLLPRIKKARPDLP-VLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 29.2 bits (65), Expect = 0.038 Identities = 21/140 (15%), Positives = 35/140 (25%), Gaps = 5/140 (3%) Query: 299 IVVEASARGATQAQFPELPTPSVPDAQVFAEPAQYEERFVDGSPQLRLTRRYSIVPNRAG 358 V A + Q ELP P+ P + PA E P + P Sbjct: 26 GAVVAGLLYTSVHQVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEP-EPEPEPI- 83 Query: 359 PLLIPGLQVAWWDVGAAAAKTASLPDLTLDVAARSAAFAAPAAAPSPASQPAGEAVAPAP 418 P V + K P V + P+ + A + Sbjct: 84 PEPPKEAPV---VIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSS 140 Query: 419 AASTLRLQGAPAASRPWGWI 438 A+ + + + + Sbjct: 141 TATAATSKPVTSVASGPRAL 160
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 36.2 bits (83), Expect = 5e-04 Identities = 19/168 (11%), Positives = 47/168 (27%), Gaps = 22/168 (13%) Query: 414 ALRQQPQLQDAIANRAAVEAARKRQQQNKDGKGKPQQ------DQNKGDKQQDQNKDGQG 467 R Q I ++A N + + + + + + Sbjct: 986 EKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSK 1045 Query: 468 KPEQTAGKDGKDGKGGQDGKPSSQPPKDGQTPGQPSPARQGEQKQPDSPPQTPDAQAQQQ 527 + +T K + Q + T A++ + + AQ+ + Sbjct: 1046 QESKTVEK-------------NEQDATE-TTAQNREVAKEAKSNVKANTQTNEVAQSGSE 1091 Query: 528 ADAAQRR--KMEQAMAQAGAKGVPSKEQQAAAAAAAETPEQREQRQAV 573 Q K + + V +++ Q ++ ++EQ + V Sbjct: 1092 TKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETV 1139 Score = 32.0 bits (72), Expect = 0.008 Identities = 24/157 (15%), Positives = 43/157 (27%), Gaps = 12/157 (7%) Query: 416 RQQPQLQDAIANRAAVEAARK----RQQQNKDGKGKPQQDQNKGDKQQDQNKDGQGKPEQ 471 Q A A EA Q G ++ + ++ + + K + Sbjct: 1055 EQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKV 1114 Query: 472 TAGKDGKDGKGGQDGKPSSQPPKDGQTPGQPSPARQGEQKQPDSPPQTPDAQAQQQADAA 531 K + K P + + Q +P+ + P + P +Q AD Sbjct: 1115 ETEKTQEVPKVTSQVSPKQEQSETVQPQAEPAR-----ENDPTVNIKEPQSQTNTTADTE 1169 Query: 532 QRRKMEQAMAQAGAKGVPSKEQQAAAAAAAETPEQRE 568 Q K + + V + E PE Sbjct: 1170 QPAKETSSN---VEQPVTESTTVNTGNSVVENPENTT 1203
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 35.2 bits (81), Expect = 3e-04 Identities = 40/158 (25%), Positives = 60/158 (37%), Gaps = 24/158 (15%) Query: 35 IVGQS----ALVERLLIALLADGHLLVEGAPGLAKTT---AIRALASRLETDFARVQ--- 84 +VG+S + L + D L++ G G K A+ R F + Sbjct: 139 LVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAA 198 Query: 85 FTPDLLPADLTG------TEIWRPQEGRFEFMPGPIFHPILLADEINRAPAKVQSALLEA 138 DL+ ++L G T GRFE G L DEI P Q+ LL Sbjct: 199 IPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGT----LFLDEIGDMPMDAQTRLLRV 254 Query: 139 MGERQVT-VGRHTYALPQLFLVMATQNPIEQ---EGTF 172 + + + T VG T + +V AT ++Q +G F Sbjct: 255 LQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLF 292
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 217 bits (553), Expect = 7e-64 Identities = 113/528 (21%), Positives = 195/528 (36%), Gaps = 63/528 (11%) Query: 141 DSLAYQTGNEYVVEITPRKGQPAVGGVSVSAVTQAAAQIAARGYSGRPVTFNFQDVPVRT 200 A G+E V + P + V+ + Q+ G V Sbjct: 117 SDAAPGIGDEVVTRVVP------LTNVAARDLAPLLRQLNDNAGVGSVV-----HYEPSN 165 Query: 201 VLQLIAEESNLN----IVASDTVQGNVTLRLMNVPWDQALDIVLRAKGLDKRRDGGVVWV 256 VL + + + IV G+ ++ + + W A D+V L+K + Sbjct: 166 VLLMTGRAAVIKRLLTIVERVDNAGDRSVVTVPLSWASAADVVKLVTELNKDTSKSALPG 225 Query: 257 APQPELAKFEQDKEDARIAIENREDLITDYVQ----------------INYHNAAVIFKA 300 + + E+ N I ++ + Y A+ + + Sbjct: 226 SMVANVVADERTNAVLVSGEPNSRQRIIAMIKQLDRQQATQGNTKVIYLKYAKASDLVEV 285 Query: 301 LTEAKGIGGGGGGGGQGGQGGAGQQDNGFLSPRGRLVADERTNTLMISDIPKKVAQMREL 360 L GI Q + A N + A +TN L+++ P + + + Sbjct: 286 L---TGISSTMQSEKQAAKPVAALDKNIIIK------AHGQTNALIVTAAPDVMNDLERV 336 Query: 361 ISHIDRPVDQVLIESRIVIATDTFARDLGARFGVTGATGRGILSGSLESNVNYLNTSAQS 420 I+ +D QVL+E+ I D +LG ++ A + L + T+ Sbjct: 337 IAQLDIRRPQVLVEAIIAEVQDADGLNLGIQWANKNAGMTQFTNSGLPIS-----TAIAG 391 Query: 421 RLEQANGGQVTTLPAHLFPSGLNVDLGAGGFTNSGAAGLAYTLLGSHFNLDIELSAMQEE 480 + G V++ S L+ G G N + L+A+ Sbjct: 392 ANQYNKDGTVSSS----LASALSSFNGIAAGFYQG-------------NWAMLLTALSSS 434 Query: 481 GRGEVVSNPRIVTANQREGVIKQGREIGYVTISGAGVAGGGSQANVQFKEVLLELKVTPT 540 + ++++ P IVT + E G+E+ +T S +G V+ K V ++LKV P Sbjct: 435 TKNDILATPSIVTLDNMEATFNVGQEVPVLTGSQTT-SGDNIFNTVERKTVGIKLKVKPQ 493 Query: 541 ITNDNRVFLNMNVKKDEVARFITLPQYGTVPEINRREVNTAVLVADGETVVIGGVYEFTD 600 I + V L + + VA + N R VN AVLV GETVV+GG+ + + Sbjct: 494 INEGDSVLLEIEQEVSSVADAASSTSSDLGATFNTRTVNNAVLVGSGETVVVGGLLDKSV 553 Query: 601 RESVAKVPFLGDIPFLGNLFKKRGRSKEKAELLVFVTPKVLRVASAAR 648 ++ KVP LGDIP +G LF+ + K L++F+ P V+R R Sbjct: 554 SDTADKVPLLGDIPVIGALFRSTSKKVSKRNLMLFIRPTVIRDRDEYR 601 Score = 51.1 bits (122), Expect = 9e-09 Identities = 31/208 (14%), Positives = 75/208 (36%), Gaps = 29/208 (13%) Query: 175 AAAQIAARGYSGRPVTFNFQDVPVRTVLQLIAEESNLNIVASDTVQGNVTLR----LMNV 230 A + R + + +F+ ++ + +++ N ++ +V+G +T+R L Sbjct: 16 IFAALLFRPAAAEEFSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRSYDMLNEE 75 Query: 231 PWDQALDIVLRAKGLDK-RRDGGVVWVAPQPELAKFEQDKEDARIAIENREDLITDYVQI 289 + Q VL G + GV+ V + AK + A ++++T V + Sbjct: 76 QYYQFFLSVLDVYGFAVINMNNGVLKVVRSKD-AKTAAVPVASDAAPGIGDEVVTRVVPL 134 Query: 290 NYHNAAVIFKALTEAKGIGGGGGGGGQGGQGGAGQQDNGFLSPRGRLVADERTNTLMISD 349 A + L + G G +V E +N L+++ Sbjct: 135 TNVAARDLAPLLRQLNDNAGV-----------------------GSVVHYEPSNVLLMTG 171 Query: 350 IPKKVAQMRELISHIDRPVDQVLIESRI 377 + ++ ++ +D D+ ++ + Sbjct: 172 RAAVIKRLLTIVERVDNAGDRSVVTVPL 199
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 29.1 bits (65), Expect = 0.005 Identities = 15/63 (23%), Positives = 26/63 (41%), Gaps = 2/63 (3%) Query: 89 LAVDQSLHGRGFGRALMQDAGKRILHAADTIGIRGLLVHALSADAKAFYERIGFEPSPLD 148 +AV + +G G AL+ A + G+ L ++ A FY + F +D Sbjct: 95 IAVAKDYRKKGVGTALLHKAIEWAKE-NHFCGLM-LETQDINISACHFYAKHHFIIGAVD 152 Query: 149 PMV 151 M+ Sbjct: 153 TML 155
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 108 bits (272), Expect = 4e-31 Identities = 36/112 (32%), Positives = 51/112 (45%), Gaps = 11/112 (9%) Query: 67 VYFDLDQDSLKPEFQAIMACHAKYLR--DRPSSRITLQGNADERGSREYNMGLGERRGNA 124 V F+ ++ +LKPE QA + L D + + G D GS YN GL ERR + Sbjct: 221 VLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQS 280 Query: 125 VSSALQAAGGSASQLTVVSYGEERPVCTETSE---------SCWSQNRRVEI 167 V L + G A +++ GE PV T + C + +RRVEI Sbjct: 281 VVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEI 332
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.3 bits (71), Expect = 0.004 Identities = 20/72 (27%), Positives = 35/72 (48%), Gaps = 7/72 (9%) Query: 30 RVAVLEQQQANSQANNDL---LNQLQQARSDLQALRATVEQLQHD--NEQLKQ--QSKDQ 82 + AVLEQ+ +A N+L +QL+Q S++ + + + + NE L + Q+ D Sbjct: 251 KHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDN 310 Query: 83 YLDLDGRLNRLE 94 L L + E Sbjct: 311 IGLLTLELAKNE 322
>PF06580#Sensor histidine kinase Length = 349 Score = 32.5 bits (74), Expect = 0.002 Identities = 35/212 (16%), Positives = 71/212 (33%), Gaps = 26/212 (12%) Query: 126 ERKQHEQHLQLLINELN-HRVKNSLVMVQSLARQSLKNAESLDDANEKIDARLMALSS-A 183 E L L ++N H + N+L +++L + A + L +LS Sbjct: 155 ASMAQEAQLMALKAQINPHFMFNALNNIRALILEDPTKAREM----------LTSLSELM 204 Query: 184 HNTLTREN--WVS-ADIAELTRDAVELCESHQGQRFELHGSSCRLDP--RRALALAMALH 238 +L N VS AD + ++L R + +++P M + Sbjct: 205 RYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFE---NQINPAIMDVQVPPMLVQ 261 Query: 239 ELCTNAVKHG-ALSSAEGRVRIAWECTMREGENRLELLWQESGGPEVQP-PQRKGFGSRL 296 L N +KHG A G++ + + + L + +G ++ + G G + Sbjct: 262 TLVENGIKHGIAQLPQGGKILL----KGTKDNGTVTLEVENTGSLALKNTKESTGTGLQN 317 Query: 297 LERGLKHDLNGDVSWVFDTAGVSYRVSLALPA 328 + L+ + + +P Sbjct: 318 VRERLQMLYGTEAQIKLSEKQGKVNAMVLIPG 349
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 51.0 bits (122), Expect = 8e-11 Identities = 23/119 (19%), Positives = 52/119 (43%), Gaps = 9/119 (7%) Query: 3 ARVLVVEDESLVAMLLEDCLAELGYEVAGTVGDVSTALEAVKKGNLDMAVLDVNLGGTMS 62 A +LV +D++ + +L L+ GY+V + +T + G+ D+ V DV + + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVR-ITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 63 FPIAEELDAR--GVPYIFVTGYASSG-IPEKFRHR--HGVQKPFRFRDLQDALALLQKA 116 F + + +P + ++ + + + KPF DL + + ++ +A Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPF---DLTELIGIIGRA 118
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 67.5 bits (165), Expect = 3e-13 Identities = 24/116 (20%), Positives = 53/116 (45%), Gaps = 2/116 (1%) Query: 2202 QVPLVMVVDDSLTMRKVTSRVLERHNLDVTTARDGVEALELLEERVPDLMLLDIEMPRMD 2261 ++V DD +R V ++ L R DV + + DL++ D+ MP + Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 2262 GYELATAMRADPRFKAVPIVMITSRSGEKHRQRAFEIGVQRYLGKPYQELDLMRNV 2317 ++L ++ +P++++++++ +A E G YL KP+ +L+ + Sbjct: 62 AFDLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGII 115
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 68.3 bits (167), Expect = 8e-14 Identities = 22/116 (18%), Positives = 50/116 (43%), Gaps = 4/116 (3%) Query: 1059 LLLVEDDVTVAQVIVGLLQGRGHHVTHVLHGLAALAEVSARSFDAGLCDLDLPGLDGAAL 1118 +L+ +DD + V+ L G+ V + ++A D + D+ +P + L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 1119 VAQLRARGVCFPIVAVTARADADAEPQALAAGCNGFLRKPL----TGDLLAQALAQ 1170 + +++ P++ ++A+ +A G +L KP ++ +ALA+ Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 75.6 bits (186), Expect = 4e-16 Identities = 28/129 (21%), Positives = 58/129 (44%), Gaps = 2/129 (1%) Query: 1052 RILLVEDDPTVAEVISGLLAGRGHRVVHAAHGLAALSEAVDGEFDVALLDLDLPGLDGFA 1111 IL+ +DD + V++ L+ G+ V ++ G+ D+ + D+ +P + F Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 1112 LAAQLRRLGHAFPLLAVTARADGDAQTQAQAAGFDGFLRKPVTADMLVEAIAAVQAVARE 1171 L ++++ P+L ++A+ +A G +L KP L+ I +A+A Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG--RALAEP 122 Query: 1172 RDRATPLLG 1180 + R + L Sbjct: 123 KRRPSKLED 131
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 77.2 bits (190), Expect = 1e-16 Identities = 28/123 (22%), Positives = 51/123 (41%) Query: 1071 RILLVEDEPTIAEVIVGLLRAQGHSVVHAPHGLAALTEAADNAFDLALLDLDLPGLDGFA 1130 IL+ +D+ I V+ L G+ V + A DL + D+ +P + F Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 1131 LARQLRVFGYDMPLIAVTARSDEAAEPTAQQAGFDSFLRKPLTGDMLADTIAEALRRVRP 1190 L +++ D+P++ ++A++ A + G +L KP L I AL + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 1191 REE 1193 R Sbjct: 125 RPS 127
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 119 bits (301), Expect = 1e-31 Identities = 84/408 (20%), Positives = 172/408 (42%), Gaps = 17/408 (4%) Query: 17 LLWLVSLAIFMQMLDATIVNTALPSMARSLRESPLQMQSVVFSYALAVAMFIPASGWIAD 76 L+WL L+ F +L+ ++N +LP +A + P V ++ L ++ G ++D Sbjct: 16 LIWLCILS-FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSD 74 Query: 77 RFGTRRTFLAAIIVFTLGSLLCAAAQQ-LPQLVAARVVQGIGGAMLLPVGRLAVLKTVAR 135 + G +R L II+ GS++ L+ AR +QG G A + + V + + + Sbjct: 75 QLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPK 134 Query: 136 ADFLRAMSFIAIPALIGPLIGPTLGGWLVEIASWHWVFLINLP-IGVIGFIAALKIMPDH 194 + +A I +G +GP +GG + HW +L+ +P I +I +K++ Sbjct: 135 ENRGKAFGLIGSIVAMGEGVGPAIGGMIAH--YIHWSYLLLIPMITIITVPFLMKLLKKE 192 Query: 195 YGDARKRFDLVGYLMLAFGMVALSLALDGIAELGLRHAFVMLLAIGGLAALAGYWLHAAS 254 + FD+ G ++++ G+V L + V+ I + H Sbjct: 193 -VRIKGHFDIKGIILMSVGIVFFMLFTT-SYSISFLIVSVLSFLI--------FVKHIRK 242 Query: 255 APAALFPLALFKVASYRIGILGNLFARVGSGSMPFLIPLLLQVGLGMSPMNAG-LMMVPV 313 L K + IG+L ++P +++ +S G +++ P Sbjct: 243 VTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPG 302 Query: 314 ALAGMAAKRAAVKLVGRFGYRRILMLNTVLVGLAMASFALISAGQPLWLRVLQLACFGAV 373 ++ + LV R G +L + + ++ + + + ++ ++ + G + Sbjct: 303 TMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGL 362 Query: 374 NSLQFTVMNTVTLRDLDRDQASPGNSLLSMVMMLATGFGAAAAGSLLA 421 + + TV++T+ L + +A G SLL+ L+ G G A G LL+ Sbjct: 363 SFTK-TVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>PF06580#Sensor histidine kinase Length = 349 Score = 36.0 bits (83), Expect = 4e-04 Identities = 20/134 (14%), Positives = 38/134 (28%), Gaps = 51/134 (38%) Query: 399 LVRNAMDHGIEPADVRVANGKPARGTVGLNAFHDSGSIVIQITDDGGGLNRDKILAKALE 458 LV N + HGI P G + L D+G++ +++ + G ++ Sbjct: 263 LVENGIKHGIAQ--------LPQGGKILLKGTKDNGTVTLEVENTGSLALKNTK------ 308 Query: 459 RGLVEPGRQLSDREVFAMIFEPGFSTAEKVTNLSGRGVGMDVVKRNITALRGC---VDID 515 G G+ V+ + L G + + Sbjct: 309 ---------------------------------ESTGTGLQNVRERLQMLYGTEAQIKLS 335 Query: 516 STAGVGTTISVRLP 529 G + V +P Sbjct: 336 EKQGKVNAM-VLIP 348
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 35.3 bits (81), Expect = 5e-05 Identities = 11/53 (20%), Positives = 21/53 (39%) Query: 109 ILVSSFVAGQGLGRQLMRKLVKWARRKYLDCLYGDVLQSNLPMLQLAESLGFK 161 I V+ +G+G L+ K ++WA+ + L + N+ F Sbjct: 95 IAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFI 147
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 83.0 bits (205), Expect = 1e-20 Identities = 37/136 (27%), Positives = 60/136 (44%), Gaps = 1/136 (0%) Query: 6 ARVLVVEDETAIADTVLYALRSEGYVPEHCLLGREALERLRNDPADLVVLDVGLPDINGF 65 A +LV +D+ AI + AL GY + DLVV DV +PD N F Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 66 EVCRTLRS-FSEVPVIFLTARNDEIDRVLGLELGADDYMAKPFSPRELVARVRARLRRRS 124 ++ ++ ++PV+ ++A+N + + E GA DY+ KPF EL+ + L Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 125 VAVAQAEPGWQPHGAF 140 ++ E Q Sbjct: 124 RRPSKLEDDSQDGMPL 139
>PF06580#Sensor histidine kinase Length = 349 Score = 38.7 bits (90), Expect = 4e-05 Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 24/96 (25%) Query: 384 LLENA----IAFSPDGGTVQLRTQREDGQVQLLVEDRGSGVPDYAIERVFERFYSLARPQ 439 L+EN IA P GG + L+ +++G V L VE+ GS E Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE------------- 309 Query: 440 TGQRSSGLGLPFVRE-VARLHGGD--VRLRNRDGGG 472 S+G GL VRE + L+G + ++L + G Sbjct: 310 ----STGTGLQNVRERLQMLYGTEAQIKLSEKQGKV 341
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 30.0 bits (67), Expect = 0.021 Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 10/74 (13%) Query: 367 PLETYDEAAVIKHLKLGAEVPLGKAREMLAALNEWSVEN------VSAALHAAAAALELG 420 PL + AVI L A G + A++ W EN V A + AAAA Sbjct: 269 PLPAEGKFAVIGGLGSVA----GFEKNTREAVDRWIQENPNAAETVEAVFNVAAAAKVAK 324 Query: 421 MGKVAQPLRVAITG 434 + K A+P + A++G Sbjct: 325 LAKAAKPGKAAVSG 338
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 72.0 bits (176), Expect = 9e-18 Identities = 31/211 (14%), Positives = 64/211 (30%), Gaps = 18/211 (8%) Query: 1 MRVRTEEKRDTIVQAASEVFLELGFEGASMSQIAARVGGSKRTLYGYFGSKEELFVAVAK 60 + +E R I+ A +F + G S+ +IA G ++ +Y +F K +LF + Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIW- 63 Query: 61 DMSDRYFDPLLDALSRSSGPI-ADALQRFGEDVLTFLCAPPNITSWQTIIGVSGRSDVGA 119 + + + D L E ++ L + + ++ + Sbjct: 64 ---ELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 120 LFFSAGQEEGLKRFAEYLQTQVDCGQLRCDDTMLAAQQFAALVEAETLMPCLFGALK--- 176 + +R L+ + A+ A + + G + Sbjct: 121 --GEMAVVQQAQRNLCLESYDRIEQTLK---HCIEAKMLPADLMTRRAAIIMRGYISGLM 175 Query: 177 -----NPSPEYLRDATRRAVELFLVGYACKP 202 P L+ R V + L Y P Sbjct: 176 ENWLFAPQSFDLKKEARDYVAILLEMYLLCP 206
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 40.2 bits (94), Expect = 1e-05 Identities = 24/109 (22%), Positives = 41/109 (37%), Gaps = 10/109 (9%) Query: 66 EVRPQVGGIVQTRQFTEGGDVKAGQTLYQIDPATYRASYASAQATLAKAQANLRTARLKA 125 E++P IV+ EG V+ G L ++ A+A K Q++L ARL+ Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALG-------AEADTLKTQSSLLQARLEQ 150 Query: 126 DRYK-ELVQIKAISQQEGD--DTAATLGQAEADVAAGKASVETARINLA 171 RY+ I+ E D +E +V + ++ Sbjct: 151 TRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQ 199 Score = 37.5 bits (87), Expect = 8e-05 Identities = 17/102 (16%), Positives = 37/102 (36%), Gaps = 3/102 (2%) Query: 99 TYRASYASAQATLAKAQANLRTARLKADRYKELVQIKAISQQEGDDTAATLGQAEADVAA 158 Y A L ++ L + KE + + ++Q ++ L Q ++ Sbjct: 256 EQENKYVEAVNELRVYKSQLEQIESEILSAKE--EYQLVTQLFKNEILDKLRQTTDNIGL 313 Query: 159 GKASVETARINLAFARMDAPISGRIGRSSV-TPGALVTANQA 199 + + + AP+S ++ + V T G +VT + Sbjct: 314 LTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAET 355 Score = 30.2 bits (68), Expect = 0.015 Identities = 13/34 (38%), Positives = 17/34 (50%), Gaps = 1/34 (2%) Query: 65 AEVRPQVGGIVQTRQ-FTEGGDVKAGQTLYQIDP 97 + +R V VQ + TEGG V +TL I P Sbjct: 328 SVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVP 361
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1210 bits (3133), Expect = 0.0 Identities = 665/1034 (64%), Positives = 808/1034 (78%), Gaps = 6/1034 (0%) Query: 1 MARFFIDRPIFAWVLAIIVMLAGILSIATLPIAQYPSIAPPAVAITANYPGASAQTLEDT 60 MA FFI RPIFAWVLAII+M+AG L+I LP+AQYP+IAPPAV+++ANYPGA AQT++DT Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQVIEQKMKGLDNLSYMASTSESSGAVTITLTFENGTDPDTAQVQVQNKLSLATALLPQ 120 VTQVIEQ M G+DNL YM+STS+S+G+VTITLTF++GTDPD AQVQVQNKL LAT LLPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVQQQGVTVTKSATNFLNVLAFTSEDGSMSDSDLSDYVAANVQETISRVQGVGDTTLFGS 180 EVQQQG++V KS++++L V F S++ + D+SDYVA+NV++T+SR+ GVGD LFG+ Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QYSMRIWLDPDKLNNFNLTPVDVRAAIQAQNAQVSAGQLGALPAVANQQLNATITAQTRL 240 QY+MRIWLD D LN + LTPVDV ++ QN Q++AGQLG PA+ QQLNA+I AQTR Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 KTAEEFENILLRTRTDGSQVRLRDVARIELGSESYNTVGRYNGKPAAGLAIKLATGANAL 300 K EEF + LR +DGS VRL+DVAR+ELG E+YN + R NGKPAAGL IKLATGANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 DTVRAIDKSLEEQEKFFPPGMKVQKPYDTTPFVRISIEQVVHTLVEAVVLVFLVMYLFLQ 360 DT +AI L E + FFP GMKV PYDTTPFV++SI +VV TL EA++LVFLVMYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NFRATLIPTIAVPVVLLGTFGVLAVFGFTINTLTMFAMVLAIGLLVDDAIVVVENVERVM 420 N RATLIPTIAVPVVLLGTF +LA FG++INTLTMF MVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 AEEQLSPKEATRKSMDQITGALVGVALVLAAVFVPMAFFGGSTGVIYRQFSITIVSAMTL 480 E++L PKEAT KSM QI GALVG+A+VL+AVF+PMAFFGGSTG IYRQFSITIVSAM L Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLVAMVLTPALCATLLKP---GHGMATTGFFGWFNRVFDRSNGRYQGVVRHMLGKGWRY 537 SVLVA++LTPALCATLLKP H GFFGWFN FD S Y V +LG RY Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 Query: 538 MIAYVVIVALVVVGFMKTPVGFLPDEDQGTLFVLVQLPPGATDARTGAVLKQVEHHFLVD 597 ++ Y +IVA +VV F++ P FLP+EDQG ++QLP GAT RT VL QV ++L + Sbjct: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 Query: 598 QKDSVAGIFAVSGFSFAGTGQNVGFAFVKLRPWDERTGKGQSVTDVAAKAGAFFATLRDA 657 +K +V +F V+GFSF+G QN G AFV L+PW+ER G S V +A +RD Sbjct: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG 660 Query: 658 QVFAVAPPAVSELGNATGFDLMLQDRANLGHAALMQARNQLLAELSQD-KRLVAVRPNGQ 716 V PA+ ELG ATGFD L D+A LGH AL QARNQLL +Q LV+VRPNG Sbjct: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 Query: 717 EDTPEFKLEIDPHKAEAMGVSIADINNTFSSAWGSTYVNDFIDKGRVKKVMLQADAPYRM 776 EDT +FKLE+D KA+A+GVS++DIN T S+A G TYVNDFID+GRVKK+ +QADA +RM Sbjct: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM 780 Query: 777 NPQDIDRWFVRNSAGTMVPFNAFATARWTQGSPRLERYNSLPSVEILGMALPGAASSGQA 836 P+D+D+ +VR++ G MVPF+AF T+ W GSPRLERYN LPS+EI G A PG SSG A Sbjct: 781 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPG-TSSGDA 839 Query: 837 MQIVEAAAAKLPAGIGFEWTGLSRQEKASTGQTGLLYGLSILIVFLCLAALYESWSIPFS 896 M ++E A+KLPAGIG++WTG+S QE+ S Q L +S ++VFLCLAALYESWSIP S Sbjct: 840 MALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVS 899 Query: 897 VILVVPLGVFGTLVAAVLTWKMNDVYFQVGLLTTIGLASKNAILIVEFAKELHE-GGKSL 955 V+LVVPLG+ G L+AA L + NDVYF VGLLTTIGL++KNAILIVEFAK+L E GK + Sbjct: 900 VMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGV 959 Query: 956 VAAALEAARMRLRPILMTSLAFILGVVPLVLTSGAGAGAQHALGTAVIGGMISGTVLAIF 1015 V A L A RMRLRPILMTSLAFILGV+PL +++GAG+GAQ+A+G V+GGM+S T+LAIF Sbjct: 960 VEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIF 1019 Query: 1016 FVPLFFVLVRGLFE 1029 FVP+FFV++R F+ Sbjct: 1020 FVPVFFVVIRRCFK 1033 Score = 62.9 bits (153), Expect = 5e-12 Identities = 48/334 (14%), Positives = 106/334 (31%), Gaps = 18/334 (5%) Query: 711 VRPNGQEDTPEFKLEIDPHKAEAMGVSIADINNTFSSA----WGSTYVNDFIDKGRVKKV 766 V+ G + ++ +D ++ D+ N G+ Sbjct: 175 VQLFGAQY--AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNA 232 Query: 767 MLQADAPYRMNPQDIDRWFVR-NSAGTMVPFNAFATARWTQGSPR-LERYNSLPSVEILG 824 + A ++ NP++ + +R NS G++V A + + R N P+ + Sbjct: 233 SIIAQTRFK-NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGI 291 Query: 825 MALPGA---ASSGQAMQIVEAAAAKLPAGIGFEW---TGLSRQEKASTGQTGLLYGLSIL 878 GA ++ + P G+ + T Q L I+ Sbjct: 292 KLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEA--IM 349 Query: 879 IVFLCLAALYESWSIPFSVILVVPLGVFGTLVAAVLTWKMNDVYFQVGLLTTIGLASKNA 938 +VFL + ++ + VP+ + GT + G++ IGL +A Sbjct: 350 LVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDA 409 Query: 939 ILIVE-FAKELHEGGKSLVAAALEAARMRLRPILMTSLAFILGVVPLVLTSGAGAGAQHA 997 I++VE + + E A ++ ++ ++ +P+ G+ Sbjct: 410 IVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQ 469 Query: 998 LGTAVIGGMISGTVLAIFFVPLFFVLVRGLFERR 1031 ++ M ++A+ P + Sbjct: 470 FSITIVSAMALSVLVALILTPALCATLLKPVSAE 503
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 42.9 bits (101), Expect = 2e-06 Identities = 28/210 (13%), Positives = 62/210 (29%), Gaps = 9/210 (4%) Query: 227 QLTLRQAQTTVESARVDVERYTAQVAQDRNALVLLVGTQLPESLLPRALPDGASVEGNVL 286 +LT A+ + + + + + + + +LPE LP P +V + Sbjct: 126 KLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLP-DEPYFQNVSEEEV 184 Query: 287 AAVPAGVPSQLLQRRPDILEAERNLRAANANIGAARAAFFPSISLTATLGSSSSSLSGLF 346 + + + Q + + E NL A A +L+ S S L Sbjct: 185 LRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLL 244 Query: 347 ESGTRAWSFVPQLTLPLFNAGRNRANLDMAKANRDIEVARYEKSIQTAFREVSDALAQRD 406 + + + A ++ +E E ++ L + + Sbjct: 245 HKQ-----AIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNE 299 Query: 407 TLGRQLQAQQALVDATADSYRLSQARFERG 436 L + Q + T L++ + Sbjct: 300 ILDKLRQTTDNIGLLTL---ELAKNEERQQ 326
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 64.3 bits (156), Expect = 1e-14 Identities = 40/209 (19%), Positives = 66/209 (31%), Gaps = 8/209 (3%) Query: 1 MPAPGRRVPHAKRGATLAAAQQLFTQQGFERTSMDRIAEDAGVSKATVYAYFASKEVLFR 60 M ++ R L A +LF+QQG TS+ IA+ AGV++ +Y +F K LF Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 TTLEAMAHAASNRWDGLL-TLPGPVAQRLAAVASVLLQVWTNAARQDAAYGLVRPPSLPS 119 E PG L + +L+ R+ ++ Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 120 ---QIREEMWTLCFERYDSTMRALLAREVAQGALVIDNLPD-ASVQFFGLITAVPTEVPA 175 + ++ + L + L D + A++ G I+ + Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180 Query: 176 PGMPPDAATAQRYIDGAVAAFLRAYRPVP 204 D R VA L Y P Sbjct: 181 APQSFDLKKEARD---YVAILLEMYLLCP 206
>cloacin#Cloacin signature. Length = 551 Score = 33.5 bits (76), Expect = 8e-04 Identities = 21/77 (27%), Positives = 34/77 (44%), Gaps = 8/77 (10%) Query: 105 GGSTPTTPGWTSGGGSSGAGRSGTGGARVSSGLSEGDV-------LPDLIDGDAGLPVLA 157 GG + + W G G G +G G +G + V P L AG ++ Sbjct: 47 GGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGGLAVS 106 Query: 158 IVA-LLAASVAALVAAV 173 I A L+A++A ++AA+ Sbjct: 107 ISAGALSAAIADIMAAL 123
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 88.7 bits (220), Expect = 3e-21 Identities = 37/175 (21%), Positives = 83/175 (47%), Gaps = 3/175 (1%) Query: 439 VIGPSLGAENVERGVTAVVFSFVFTLVFFTVYYRMFGAITSV-ALLFNLLIVIAVMSLFG 497 +GP + E V V +++ + V + + V + A+ +V AL+ ++L+ + + ++ Sbjct: 142 SVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGAVVALVHDVLLTVGLFAVLQ 201 Query: 498 ATMTLPGFAGLALSVGLSVDANVLINERIREELRL--GVPPKSAIVAGYEKAGGTILDAN 555 L A L G S++ V++ +R+RE L +P + + + + Sbjct: 202 LKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRDVMNLSVNETLSRTVMTG 261 Query: 556 LTGLIVGVALYAFGTGPLKGFALTMIIGIFASMFTAITVSRALAVLIYGSRKKLK 610 +T L+ V + +G ++GF M+ G+F ++++ V++ + + I R K K Sbjct: 262 MTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAKNIVLFIGLDRNKEK 316
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 282 bits (722), Expect = 3e-96 Identities = 97/320 (30%), Positives = 161/320 (50%), Gaps = 10/320 (3%) Query: 4 FPLHLIPNDTKIDFMRLRKPVLILMLVLAIASIGIIVGKGFNYALEFTGGTLVQTSFQKT 63 F L L+P T DF R + +V+ IAS+ + + G N+ ++F GGT ++T Sbjct: 3 FRLKLVPEKTNFDFFRWQWATFGAAIVMMIASVILPLVIGLNFGIDFKGGTTIRTESTTA 62 Query: 64 VDVDQVREQLAKAGFENAQVQNAR------GGNEVMIRLQAREQHNNRDDAAT---TVAE 114 +DV R L + + R + MIR+Q +E + + Sbjct: 63 IDVGVYRAALEPLELGDVIISEVRDPSFREDQHVAMIRIQMQEDGQGAEGQGAQGQELVN 122 Query: 115 EVRKAVSTEQNPATVQPGEFVGPQVGKDLALNGVYATVFMLVGFLIYIAFRFEWKFAVVA 174 +V A++ + E VGP+V +L V++ + V + YI RFEW+FA+ A Sbjct: 123 KVETALTAVDPALKITSFESVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGA 182 Query: 175 SLTALFDLLVTVAFVSLTGREFDLTVLAGLLSVMGFAINDIIVVFDRVRENFRALRVEPL 234 + + D+L+TV ++ +FDLT +A LL++ G++IND +VVFDR+REN + PL Sbjct: 183 VVALVHDVLLTVGLFAVLQLKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPL 242 Query: 235 -EVLNRSINQTLSRTVITAVMFFLSALALYIYGGESMEGLAETHMIGAVIVVISSIIVAV 293 +V+N S+N+TLSRTV+T + L+ + + I+GG+ + G + G SS+ VA Sbjct: 243 RDVMNLSVNETLSRTVMTGMTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAK 302 Query: 294 PMLSIGPFAVTKQDLLPKAK 313 ++ K+ P K Sbjct: 303 NIVLFIGLDRNKEKKDPSDK 322
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 31.9 bits (72), Expect = 0.010 Identities = 26/104 (25%), Positives = 43/104 (41%), Gaps = 8/104 (7%) Query: 53 LTNGAAHVLIVGDADADTARFGDAQLLHLSLGAVLDDPAAAVSQLAATTAPASTSATTDA 112 + + + I+ +ADADT A + L+ VL + +SQ A +T+ A Sbjct: 248 ILSAISASFILSNADADTRTKAAAG-VELTT-KVLGNVGKGISQYIIAQRAAQGLSTSAA 305 Query: 113 SGAGGKRIVAITSCP---TGIAHTFMAAEGLQQAA---KKLGYQ 150 + V + P IA F A +++ + KKLGY Sbjct: 306 AAGLIASAVTLAISPLSFLSIADKFKRANKIEEYSQRFKKLGYD 349
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 587 bits (1516), Expect = 0.0 Identities = 210/568 (36%), Positives = 323/568 (56%), Gaps = 11/568 (1%) Query: 274 AIVGIGASPGVAIGIVHRLRAAQTEVADQPIGLGDGGV-LLHDALTRTRQQLAAIQDDTQ 332 I GI AS GVAI ++ I + L AL +++++L AI+D T+ Sbjct: 4 KITGIAASSGVAIAKAFIHLEPNVDIEKTSITDVSTEIEKLTAALEKSKEELRAIKDQTE 63 Query: 333 RRLGASDAAIFKAQAELLNDTDLITR-TCQLMVEGHGVAWSWHQAVEQIASGLAALGNPV 391 +GA A IF A +L+D +L+ ++ E ++ + + S ++ N Sbjct: 64 ASMGADKAEIFAAHLLVLDDPELVDGIKGKIENEQMNAEYALKEVSDMFVSMFESMDNEY 123 Query: 392 LAGRAADLRDVGRRVLAQLDPAAAGAGLTDLPEQPCILLAGDLSPSDTANLDTDCVLGLA 451 + RAAD+RDV +RVL L G+ L + E +++A DL+PSDTA L+ V G A Sbjct: 124 MKERAADIRDVSKRVLGHLIGVETGS-LATIAE-ETVIIAEDLTPSDTAQLNKQFVKGFA 181 Query: 452 TAQGGPTSHTAILSRTLGLPALVAAGGQLLDIEDGVTAIIDGSSGRLYINPSEQDLDAAR 511 T GG TSH+AI+SR+L +PA+V I+ G I+DG G + +NP+E+++ A Sbjct: 182 TDIGGRTSHSAIMSRSLEIPAVVGTKEVTEKIQHGDMVIVDGIEGIVIVNPTEEEVKAYE 241 Query: 512 THIAEQQAIREREAAQRALPAETTDGHHIDIGANVNLPEQVAMALTQGAEGVGLMRTEFL 571 A + ++ A P+ T DG H+++ AN+ P+ V L G EG+GL RTEFL Sbjct: 242 EKRAAFEKQKQEWAKLVGEPSTTKDGAHVELAANIGTPKDVDGVLANGGEGIGLYRTEFL 301 Query: 572 FLERGSTPTEDEQYQTYLAMARALDGRPLIVRALDIGGDKQVAHLELPHEENPFLGVRGA 631 +++R PTE+EQ++ Y + + +DG+P+++R LDIGGDK++++L+LP E NPFLG R Sbjct: 302 YMDRDQLPTEEEQFEAYKEVVQRMDGKPVVIRTLDIGGDKELSYLQLPKELNPFLGFRAI 361 Query: 632 RLLLRRPDLLEPQLRALYRAAKDGARLSIMFPMITSVPELISLREICARIRAELDA---- 687 RL L + D+ QLRAL RA+ G L +MFPMI ++ EL + I + +L + Sbjct: 362 RLCLEKQDIFRTQLRALLRASTYG-NLKVMFPMIATLEELRQAKAIMQEEKDKLLSEGVD 420 Query: 688 --PELPIGIMIEVPAAAAQADVLARHADFFSIGTNDLTQYVLAIDRQNPELAAEADSLHP 745 + +GIM+E+P+ A A++ A+ DFFSIGTNDL QY +A DR N ++ HP Sbjct: 421 VSDSIEVGIMVEIPSTAVAANLFAKEVDFFSIGTNDLIQYTMAADRMNERVSYLYQPYHP 480 Query: 746 AVLRMIRSTIDGARKHDRWVGVCGGLAGDPFGASLLAGLGVQELSMTPNDIPAVKARLRG 805 A+LR++ I A +WVG+CG +AGD LL GLG+ E SM+ I +++L Sbjct: 481 AILRLVDMVIKAAHSEGKWVGMCGEMAGDEVAIPLLLGLGLDEFSMSATSILPARSQLLK 540 Query: 806 RALSALQQLAEQALQCETAEQVRALEAQ 833 + L+ A++AL +TAE+V L + Sbjct: 541 LSKEELKPFAQKALMLDTAEEVEQLVKK 568
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1089 bits (2817), Expect = 0.0 Identities = 525/1038 (50%), Positives = 710/1038 (68%), Gaps = 17/1038 (1%) Query: 1 MPKFFIEHPVFAWVVAILISLAGVISILNLGIESYPTIAPPQVTVTANFPGASADTAEKA 60 M FFI P+FAWV+AI++ +AG ++IL L + YPTIAPP V+V+AN+PGA A T + Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQVIEQQLTGIDHLLYFNSSSASNGRVTITLTFETGTDADIAQVQVQNKVSLATPRLPS 120 VTQVIEQ + GID+L+Y +S+S S G VTITLTF++GTD DIAQVQVQNK+ LATP LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVTQQGVVVAKANAGFLMVAALRSDNPSIDRDALNDIVGSRVLEQISRVPGVGSTNQFGA 180 EV QQG+ V K+++ +LMVA SDNP +D ++D V S V + +SR+ GVG FGA Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 EYAMNIWLNPEKLQGYNLSATQVLTAVRNQNVQFAAGSVGADPTPQGISFTATVSAEGRF 240 +YAM IWL+ + L Y L+ V+ ++ QN Q AAG +G P G A++ A+ RF Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 SSPQEFENIILRTDNNGATVRLKDVARVTVGPSNYGFDTQYNGKPTGAFGIQLLPGANAL 300 +P+EF + LR +++G+ VRLKDVARV +G NY + NGKP GI+L GANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 NVSEAVGAKLDELQPTFPQGVTWFAPYESTTFVRISIEEVVHTLVEAIVLVFLVMLLFLQ 360 + ++A+ AKL ELQP FPQG+ PY++T FV++SI EVV TL EAI+LVFLVM LFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NFRATVIPTLVIPVALLGTFFGMYVIGFTINQLTLFAMVLAIGIVVDDAIVVIENVERIM 420 N RAT+IPT+ +PV LLGTF + G++IN LT+F MVLAIG++VDDAIVV+ENVER+M Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 SEEHLEPKAATQKAMTQITGAVVAITVVLAAVFIPSAMQPGASGAIYKQFALTIAMAMAF 480 E+ L PK AT+K+M+QI GA+V I +VL+AVFIP A G++GAIY+QF++TI AMA Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SAFLALSFTPALCAAFLK---STHSDKKNWIYRTFDKYYDKLAHRYVGVVGNTLKRSPAW 537 S +AL TPALCA LK + H + K + F+ +D + Y VG L + + Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 Query: 538 MVVFVVLVVLCGFLFTRMPGSFLPEEDQGFAVAIVQLPPGATKIRTNEAFAQMRAVLEKQ 597 ++++ ++V LF R+P SFLPEEDQG + ++QLP GAT+ RT + Q+ K Sbjct: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 Query: 598 PA--VEGMLQIAGFSFLGSGENVGMGFIRLKPWEERDV---TAEQLIQQLNGAFYGIKGA 652 VE + + GFSF G +N GM F+ LKPWEER+ +AE +I + I+ Sbjct: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG 660 Query: 653 QIFVVNLPTVQGLGQFGGFDMWLQDRSGAGQEALTQARNIVLGKAAQKQDTVVGVRPNGL 712 + N+P + LG GFD L D++G G +ALTQARN +LG AAQ ++V VRPNGL Sbjct: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 Query: 713 ENSPQLQLHVDRVQAQSMGLEVSDIYSSIQLMLAPVYVNDYFSEGRIKRVNIRADDQFRT 772 E++ Q +L VD+ +AQ++G+ +SDI +I L YVND+ GR+K++ ++AD +FR Sbjct: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM 780 Query: 773 GPESLRNFFTPSSTATGADGQPGMIPLSNVVKAEWTYASPALNRYNGYSAVNIVGNPAPG 832 PE + + S A+G+ M+P S + W Y SP L RYNG ++ I G APG Sbjct: 781 LPEDVDKLYVRS-----ANGE--MVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPG 833 Query: 833 GSSGQAMQAMEEIVNNDLPPGFGFDWSGMSYQEIIAGNAATLLLALSVVVVFLCLAALYE 892 SSG AM ME + + LP G G+DW+GMSYQE ++GN A L+A+S VVVFLCLAALYE Sbjct: 834 TSSGDAMALMENLASK-LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYE 892 Query: 893 SWSIPVAVLLVVPIGVLGAITFSMLRGLPNDLYFKIGMITVIGLAAKNAILIVEFAVE-Q 951 SWSIPV+V+LVVP+G++G + + L ND+YF +G++T IGL+AKNAILIVEFA + Sbjct: 893 SWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLM 952 Query: 952 RAAGKTLREATLEAAHLRFRPILMTSFAFILGVLPLAISTGAGANSRHSIGTGVIGGMVF 1011 GK + EATL A +R RPILMTS AFILGVLPLAIS GAG+ +++++G GV+GGMV Sbjct: 953 EKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVS 1012 Query: 1012 ATVLGVIFIPLFFVVVRR 1029 AT+L + F+P+FFVV+RR Sbjct: 1013 ATLLAIFFVPVFFVVIRR 1030 Score = 77.2 bits (190), Expect = 2e-16 Identities = 86/536 (16%), Positives = 188/536 (35%), Gaps = 47/536 (8%) Query: 533 RSPAWMVVFVVLVVLCGFL-FTRMPGSFLPEEDQGFAVAIVQLP-PGATKIRTNEAFAQM 590 R P + V +++++ G L ++P + P V PGA + Sbjct: 7 RRPIFAWVLAIILMMAGALAILQLPVAQYPTIA--PPAVSVSANYPGAD---AQTVQDTV 61 Query: 591 RAVLEKQ-PAVEGMLQIAGFSFLGSGENVGMGFIRLKPWEERDVTAEQLIQQLNGAFY-- 647 V+E+ ++ ++ ++ S + + F + + D+ Q+ +L A Sbjct: 62 TQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTF---QSGTDPDIAQVQVQNKLQLATPLL 118 Query: 648 --GIKGAQIFVVNLPTVQGLGQFGGFDMWLQDRSGAGQEALTQARNIVLGKAAQKQDTVV 705 ++ I V + + ++ D G Q+ ++ + + + V Sbjct: 119 PQEVQQQGISVEKSSSSYLM-----VAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVG 173 Query: 706 GVRPNGLENSPQLQLHVDRVQAQSMGLEVSDIYSSIQLMLAPV----YVNDYFSEGRIKR 761 V+ G + + ++ L D + L D+ + +++ + G+ Sbjct: 174 DVQLFGAQYAMRIWLDADLLNKY--KLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLN 231 Query: 762 VNIRADDQFRTGPESLRNFFTPSSTATGADGQPGMIPLSNVVKAEWTYASPA-LNRYNGY 820 +I A +F+ PE + +DG + L +V + E + + R NG Sbjct: 232 ASIIAQTRFKN-PEEFGK----VTLRVNSDGSV--VRLKDVARVELGGENYNVIARINGK 284 Query: 821 SAVNIVGNPAPGGS----SGQAMQAMEEIVNNDLPPGFG----FDWSGMSYQEIIAGNAA 872 A + A G + + + E+ P G +D + Q I Sbjct: 285 PAAGLGIKLATGANALDTAKAIKAKLAEL-QPFFPQGMKVLYPYDTTPF-VQLSIHEVVK 342 Query: 873 TLLLALSVVVVFLCLAALYESWSIPVAVLLVVPIGVLGAITFSMLRGLPNDLYFKIGMIT 932 TL A +++VFL + ++ + + VP+ +LG G + GM+ Sbjct: 343 TLFEA--IMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVL 400 Query: 933 VIGLAAKNAILIVEFAVEQRAAGKTL-REATLEAAHLRFRPILMTSFAFILGVLPLAIST 991 IGL +AI++VE K +EAT ++ ++ + +P+A Sbjct: 401 AIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFG 460 Query: 992 GAGANSRHSIGTGVIGGMVFATVLGVIFIPLFFVVVRRMLGDKLDEPPKEYLAVQN 1047 G+ ++ M + ++ +I P + + + + E + N Sbjct: 461 GSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFN 516
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 42.5 bits (100), Expect = 2e-06 Identities = 15/109 (13%), Positives = 41/109 (37%), Gaps = 7/109 (6%) Query: 59 RSADVRARVDGVLLKRLYTEGTDVKEGQPLFEIDPMPLRATLLQAQGQLAAAEATYANAK 118 RS +++ + ++ + + EG V++G L ++ L A+ +++ A+ Sbjct: 95 RSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTA-------LGAEADTLKTQSSLLQAR 147 Query: 119 IAAQRARSLAPQQYVSRADIDTAEATERSSGASVQQARGVVESASIQLS 167 + R + L+ +++ S ++ + Q S Sbjct: 148 LEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFS 196
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 57.7 bits (139), Expect = 2e-12 Identities = 29/172 (16%), Positives = 57/172 (33%), Gaps = 9/172 (5%) Query: 5 SPRAARRSDCDRRIHAAVHALLAERGMR-VSMTAVAERAGCSKQTLYSHYGCKENLLRDV 63 + + I L +++G+ S+ +A+ AG ++ +Y H+ K +L ++ Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 64 LQEHV----QLATVPLGTATGDLREDLLAFALAHLDRLNRPDV---LQTCRLVEAESHRF 116 + +L GD L + L+ + L + E Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 117 PGQSQQIFHEGVVGMQERLASRFAQAIDAGQLRHD-DPHFMAELLLSMIVGL 167 QQ + +R+ I+A L D A ++ I GL Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGL 174
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 116 bits (292), Expect = 2e-30 Identities = 80/411 (19%), Positives = 161/411 (39%), Gaps = 17/411 (4%) Query: 24 LILACAI-FMEQMDATVLATALPTLARDFGVAAPAMSIAMTSYLLALAVLIPASGAIADR 82 LI C + F ++ VL +LP +A DF + + T+++L ++ G ++D+ Sbjct: 16 LIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQ 75 Query: 83 FGLRRVFSASIWVFIGGSILCSLADS-LPTMVAARVLQGAGGAMMAPLGRLILLRTVERR 141 G++R+ I + GS++ + S ++ AR +QGAG A L +++ R + + Sbjct: 76 LGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKE 135 Query: 142 HLVSAMAWTLVPAFIGPMLGPPLGGFFVSYLDWRWIFYINVPIGITGFLLVRRFIPDIPS 201 + A +G +GP +GG Y+ W ++ I + IT L + + Sbjct: 136 NRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFL-MKLLK--KE 192 Query: 202 ESAPARFDLRGFVLCGTALGCLLFGLEMVSQEDGIPRASWLLAIGGATALG-YLWHARQH 260 FD++G +L + + S I + ++ H R+ Sbjct: 193 VRIKGHFDIKGIILMSVGIVFFMLFTTS---------YSISFLIVSVLSFLIFVKHIRKV 243 Query: 261 PAPLLDLSLLRIDSFRLSVIGGALMRITQGAHPFLLPLLFQISFGFSAARSGRLILATAL 320 P +D L + F + V+ G ++ T ++P + + S A G +I+ Sbjct: 244 TDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGT 303 Query: 321 GALLMRS-ITPQLLRRFGYRNSLIGNGVLASLGYMVCALFRPDWPPALMFGLLLCCGAFM 379 ++++ I L+ R G L S+ ++ + + ++ G + Sbjct: 304 MSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLG-GL 362 Query: 380 SFQFAAYNTIAYENVPAARMGRASSLYTTLQQLMLSVGVCAGAMILKLAML 430 SF +TI ++ G SL L G+ +L + +L Sbjct: 363 SFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLL 413
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 63.3 bits (154), Expect = 3e-13 Identities = 33/146 (22%), Positives = 63/146 (43%), Gaps = 6/146 (4%) Query: 1 MPARPLLCVDDESSNLATLRQLL-RDDYPLVFAKSGGEALDAVARHAPALILLDVELPDM 59 M +L DD+++ L Q L R Y + + +A L++ DV +PD Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 60 DGYAVARTLKQ-DPDSTAIPILFVTSRSTEHDERTGLEAGAADYVSRPYSAALLKARIAT 118 + + + +K+ PD +P+L +++++T E GA DY+ +P+ L I Sbjct: 61 NAFDLLPRIKKARPD---LPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117 Query: 119 HLTLAENARLAQQYRDAIHLLGTAGQ 144 L R ++ D+ + G+ Sbjct: 118 ALAE-PKRRPSKLEDDSQDGMPLVGR 142
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 73.3 bits (180), Expect = 2e-15 Identities = 35/142 (24%), Positives = 58/142 (40%), Gaps = 4/142 (2%) Query: 1029 LEGAQLLLVDDSEINCEVAQRILEGEGAMVTVAHDGEQAVNTLKRAPDLFHLVLMDVQMP 1088 + GA +L+ DD V + L G V + + + LV+ DV MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGD--GDLVVTDVVMP 58 Query: 1089 VVDGYEATRRLRQIPSLASLPVIALTAGAFRPQQEKALEAGMNGFIAKPFNVEELVTAIR 1148 + ++ R+++ LPV+ ++A KA E G ++ KPF++ EL+ I Sbjct: 59 DENAFDLLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116 Query: 1149 HFLQPGSRRVSSLPHERAPAAG 1170 L RR S L + Sbjct: 117 RALAEPKRRPSKLEDDSQDGMP 138 Score = 62.9 bits (153), Expect = 5e-12 Identities = 23/115 (20%), Positives = 46/115 (40%), Gaps = 13/115 (11%) Query: 889 SMPRVLIADDHDAALNNLVRIATELGWRVDAVASGQAAMQAIEDATEPYDIFLLDWRMPD 948 + +L+ADD A L + + G+ V ++ + I D+ + D MPD Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAA--GDGDLVVTDVVMPD 59 Query: 949 IDGVAIARQVRARATPGRHPVIVM---------VTAYERRLLEQHPEQQDLDAVM 994 + + +++ PV+VM + A E+ + P+ DL ++ Sbjct: 60 ENAFDLLPRIKKARP--DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELI 112
>TRNSINTIMINR#Translocated intimin receptor (Tir) signature. Length = 549 Score = 29.7 bits (66), Expect = 0.027 Identities = 21/112 (18%), Positives = 46/112 (41%), Gaps = 5/112 (4%) Query: 318 SEIREALRNDLAKEDSSMAAHMERSMQSLGQSLSQDPS--LRDALNVHMLDAADKLTTRL 375 + A ++ L +E + + ++ + G ++ PS L+D + + A + Sbjct: 276 NAAESATKDQLTQEAFKNPENQKVNIDANGNAI---PSGELKDDIVEQIAQQAKEAGEVA 332 Query: 376 RASVTEHIASTMKSWDERHLVEQLELGVGRDLQYIRFNGTLVGGLIGLALHA 427 R E A + ++++H Q EL + + Y + +V G IG + Sbjct: 333 RQQAVESNAQAQQRYEDQHARRQEELQLSSGIGYGLSSALIVAGGIGAGVTT 384
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 36.2 bits (83), Expect = 1e-04 Identities = 31/181 (17%), Positives = 56/181 (30%), Gaps = 42/181 (23%) Query: 122 PEASDAELSVDT-------------------SDAAARPAEALDSPPWEETSTPVSRAELA 162 PE +VDT ++ AR EA PP +TP E Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAP--ATPSETTETV 1040 Query: 163 REARLSSNQVTMIERIHKQAAPEVVQAVRAGEISISAAAAVATLSEDEQRAAAQAGKAEL 222 E ++ E+ + A Q + E + A E+ Sbjct: 1041 AENSKQESKTV--EKNEQDATETTAQNREVAK-------------EAKSNVKANTQTNEV 1085 Query: 223 KQAAKRVRDAKRKPKPDEAEGGEAERRDVKALQRRVTELENENAALQTKVAALQAQLERL 282 Q+ ++ + + A + E+ + TE E + ++V+ Q Q E + Sbjct: 1086 AQSGSETKETQTTETKETATVEKEEK------AKVETEKTQEVPKVTSQVSPKQEQSETV 1139 Query: 283 R 283 + Sbjct: 1140 Q 1140
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 30.4 bits (68), Expect = 0.014 Identities = 35/167 (20%), Positives = 57/167 (34%), Gaps = 25/167 (14%) Query: 13 KQPESALRRWLKERHITEVECLVPDITGNARG--KIIPADKFSHDYGTRLPEGIFATTVT 70 K A+ RW++E P+ + A K + P V+ Sbjct: 290 KNTREAVDRWIQEN---------PNAAETVEAVFNVAAAAKVAKLAKAAKPG---KAAVS 337 Query: 71 GDFPDDYYALTSPSDSDMHLRPDASTVRMVPWAADPTAQVIHDCYTKDGQPHEL-APRNV 129 GDF D Y + SDS L +A + + + D +K E+ A N Sbjct: 338 GDFADSYKKKLALSDSARQLYQNAKYREALDIHYEDLIRRKTDGSSKFINGREIDAVTN- 396 Query: 130 LRRVLEAYAEVK--LQPVVAPELEFFLVQKNTDPDFPLLPPAGRSGR 174 +A + K + + P + FL QKN + A + G+ Sbjct: 397 -----DALIQAKRTISAIDKP--KNFLNQKNRKQIKATIEAANQQGK 436
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 96.8 bits (241), Expect = 5e-24 Identities = 54/370 (14%), Positives = 115/370 (31%), Gaps = 81/370 (21%) Query: 80 SVAVAPRVSGYVTQVMVGDNQIVDAGQPLLQIDD------------RTYQATLQQA---- 123 S + P + V +++V + + V G LL++ QA L+Q Sbjct: 96 SKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQI 155 Query: 124 ------------------------------------EAAIAAREADIAAATANVAAQESS 147 + + + N+ + + Sbjct: 156 LSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAE 215 Query: 148 LVQARTQVASAAASLRFAQAEVKRFAPLAASGA-DTHEHQE------SLQHDLERARAQY 200 + ++ R ++ + F+ L A H E ++L ++Q Sbjct: 216 RLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQL 275 Query: 201 EAAQAQAKGAQSQIQASSA--------QLEQAKAGVKQATADADQARVAVEDTRLTSRIH 252 E +++ A+ + Q + +L Q + T + + + + + + + Sbjct: 276 EQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVS 335 Query: 253 GRVGD-KTVQVGQFLAAGTRTMTIVPQQSLYLV-ANFKETQVGLMRPGQPAEIEVDALSG 310 +V K G + M IVP+ V A + +G + GQ A I+V+A Sbjct: 336 VKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPY 395 Query: 311 VK---LHGKVESLSPGTGSQFALLPPENATGNFTKVVQRVPVRIRVLAGEEARKVLVPGM 367 + L GKV++++ + G V+ + + L GM Sbjct: 396 TRYGYLVGKVKNINLDA-------IEDQRLGLVFNVIISIEENCLSTGNKNIP--LSSGM 446 Query: 368 SVEVTVDTRS 377 +V + T Sbjct: 447 AVTAEIKTGM 456
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 102 bits (255), Expect = 2e-25 Identities = 83/407 (20%), Positives = 164/407 (40%), Gaps = 20/407 (4%) Query: 25 WLAVLAGTIGSFMATLDISIVNAALPTIQGEVGASGTEGTWISTAYLVAEIIMIPLTGWF 84 WL +L SF + L+ ++N +LP I + W++TA+++ I + G Sbjct: 18 WLCIL-----SFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKL 72 Query: 85 VRTLGLRNFLLICAVMFTAFSVVCGLSTS-LTMMIIGRVGQGLAGGALIPTALTIVATRL 143 LG++ LL ++ SV+ + S +++I+ R QG A + +VA + Sbjct: 73 SDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYI 132 Query: 144 PPSQQTMGTALFGMTVIMGPVIGPLLGGWLTENVSWHYAFFINVPICVGLVALLLLGLKH 203 P + L G V MG +GP +GG + + W Y + +P+ + L+ L Sbjct: 133 PKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSY--LLLIPMITIITVPFLMKLLK 190 Query: 204 EKGNWAGLLDADWLGIYGLTAGLGGLTVVLEEGQRERWFESSEINTLSVFALSGFLALVI 263 ++ G D GI ++ G+ + +L F +S + + ++ FL V Sbjct: 191 KEVRIKGHF--DIKGIILMSVGI--VFFML--------FTTSYSISFLIVSVLSFLIFVK 238 Query: 264 SQFGQRAPVIRLSLLLHRSFGAVFIMIMAVGMILFGVMYMIPQFLSVISGYNTEQAGYVL 323 P + L + F + + + G + M+P + + +T + G V+ Sbjct: 239 HIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVI 298 Query: 324 LLSGLPTVLLMPMMPKLLEVVDVRILVIAGLLCFAAACFVNLSLTADTVGMHFVAGQLLQ 383 + G +V++ + +L + V+ + F + F+ S +T + Sbjct: 299 IFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFV 358 Query: 384 GCGLALAMMSLNQAAISSVPPELAGDASGLFNAGRNLGGSVGLALIS 430 GL+ ++ SS+ + AG L N L G+A++ Sbjct: 359 LGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVG 405
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 29.8 bits (67), Expect = 0.012 Identities = 11/50 (22%), Positives = 21/50 (42%), Gaps = 7/50 (14%) Query: 99 LLIGYP-----MAYVIARLPLATRN--VAMMLVVLPSWTSFLIRVYAWIG 141 +LIGY + +V+ +P R + +L+ + F I V + Sbjct: 120 ILIGYSFGAEVIPFVLNEMPARYRKNVLGAVLLSPSQSSDFEIHVSEMVT 169
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 28.6 bits (64), Expect = 0.031 Identities = 9/25 (36%), Positives = 14/25 (56%) Query: 229 LSRIDVKVGDRVEQGQVIAAVGATG 253 + I VK G+ V +G V+ + A G Sbjct: 107 VKEIIVKEGESVRKGDVLLKLTALG 131
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 34.3 bits (79), Expect = 9e-04 Identities = 25/97 (25%), Positives = 38/97 (39%), Gaps = 19/97 (19%) Query: 4 TVIVNARLVNEGKEFDADLLIEGGRIARI----------DSHIAPAAGDTVVDAAGRWLL 53 TVI NA +++ AD+ ++ GRIA I I G V+ G+ + Sbjct: 70 TVITNALILDHWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIVT 129 Query: 54 PGMIDDQVHFREPGLTHKGDIATESGAAVAGGLTSFM 90 G +D +HF P A+ GLT + Sbjct: 130 AGGMDSHIHFICPQQIE---------EALMSGLTCML 157
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 25.8 bits (56), Expect = 0.028 Identities = 15/79 (18%), Positives = 28/79 (35%), Gaps = 3/79 (3%) Query: 2 AAKKTAQKAVQAAKKS-AKPVAKKAAAPAAAKPAAKKATPA--AKQPVAKKAPATKTAAK 58 + +V + + A+ PA A P+ T A +KQ + A + Sbjct: 1001 NNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATE 1060 Query: 59 PAPASKPAAPNARETLSAN 77 ++ A A+ + AN Sbjct: 1061 TTAQNREVAKEAKSNVKAN 1079 Score = 25.4 bits (55), Expect = 0.038 Identities = 14/83 (16%), Positives = 29/83 (34%), Gaps = 3/83 (3%) Query: 3 AKKTAQKAVQAAKKSAKPVAKKAAAPAAAKPAAKKATPAAKQPVAK---KAPATKTAAKP 59 +KT + ++ S K + P A T K+P ++ A + A + Sbjct: 1116 TEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKET 1175 Query: 60 APASKPAAPNARETLSANDVLAN 82 + + + + N V+ N Sbjct: 1176 SSNVEQPVTESTTVNTGNSVVEN 1198
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 40.6 bits (95), Expect = 9e-06 Identities = 46/202 (22%), Positives = 71/202 (35%), Gaps = 9/202 (4%) Query: 68 FCIAPFAGYLVDHLPRRRLGMTAALGLVATALILTAITHGWLPVNGVWPIYAAIALTGAA 127 F AP G L D RR + + +L A + A +W +Y + G Sbjct: 57 FACAPVLGALSDRFGRRPV-LLVSLAGAAVDYAIMATAPF------LWVLYIGRIVAGIT 109 Query: 128 RSFLSPVYNALFARALPREAFARGASIGSVTFQAGMVIGPALGGVLVAWGGKGLAYGVAA 187 + V A A + AR S F GMV GP LGG++ + + AA Sbjct: 110 GA-TGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAA 168 Query: 188 SVALVAILALFLLRVTEPVNAGPRAPIFRSIAEGAQFVLSNQIMLGAMALDMFSVLLGGA 247 L + FLL + P + ++ ++ MA+ L+G Sbjct: 169 LNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQV 228 Query: 248 VSMLPA-FIHDILHYGPEGLGI 268 + L F D H+ +GI Sbjct: 229 PAALWVIFGEDRFHWDATTIGI 250
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 280 bits (719), Expect = 4e-87 Identities = 141/574 (24%), Positives = 236/574 (41%), Gaps = 89/574 (15%) Query: 260 KAIRMVYSDVPGERVRIEDTPVE---LRNTFSISDEDVQELSKQAL---------VIEKH 307 KA + +V E+ I D E L S E+++ + Q + H Sbjct: 18 KAFIHLEPNVDIEKTSITDVSTEIEKLTAALEKSKEELRAIKDQTEASMGADKAEIFAAH 77 Query: 308 YGRPMDIEWAKDGVSGKLFIVQARPETVKSRSHATQIERFSLEAKDAKILVEGRAVGAKI 367 D E + GK+ Q E + F E+ D + + E RA A I Sbjct: 78 LLVLDDPELVDG-IKGKIENEQMNAEYALKEVSDMFVSMF--ESMDNEYMKE-RA--ADI 131 Query: 368 GSGVARVVRSL-----EDMNRVQAGDVLIA-DMTDPDWEPVMK-RASAIVTNRGGRTCHA 420 RV+ L + + V+IA D+T D + K T+ GGRT H+ Sbjct: 132 RDVSKRVLGHLIGVETGSLATIAEETVIIAEDLTPSDTAQLNKQFVKGFATDIGGRTSHS 191 Query: 421 AIIARELGVPAVVGSGNATDVISDGQEVTVSCAEG---------DTGFIYEGLLPFERTT 471 AI++R L +PAVVG+ T+ I G V V EG + E FE+ Sbjct: 192 AIMSRSLEIPAVVGTKEVTEKIQHGDMVIVDGIEGIVIVNPTEEEVKAYEEKRAAFEKQK 251 Query: 472 TDLGNMPPAP--------LKIMMNVANPERAFDFGQLPNAGIGLARLEMIIAAHIGIHPN 523 + + P +++ N+ P+ GIGL R E + + Sbjct: 252 QEWAKLVGEPSTTKDGAHVELAANIGTPKDVDGVLANGGEGIGLYRTEFLYMDR-----D 306 Query: 524 ALLEYDKQDADVRKKIDAKIAGYGDPVSFYINRLAEGIATLTASVAPNTVIVRLSDFKSN 583 L ++Q ++ + G PV ++R D + Sbjct: 307 QLPTEEEQFEAYKEVVQRM---DGKPV-----------------------VIRTLDIGGD 340 Query: 584 EYANLIGGSRYEPHEENPMIGFRGASRYVDPSFTKAFSLECKAVLKVRNEMGLDNLWVMI 643 + + + P E NP +GFR ++ F + +A+L+ NL VM Sbjct: 341 KELSYL----QLPKELNPFLGFRAIRLCLE--KQDIFRTQLRALLRAS---TYGNLKVMF 391 Query: 644 PFVRTLEEGRKVIEVLEQNGLKQGENG------LKIIMMCELPSNALLADEFLEIFDGFS 697 P + TLEE R+ ++++ K G +++ +M E+PS A+ A+ F + D FS Sbjct: 392 PMIATLEELRQAKAIMQEEKDKLLSEGVDVSDSIEVGIMVEIPSTAVAANLFAKEVDFFS 451 Query: 698 IGSNDLTQLTLGLDRDSSIVAHLFDERNPAVKKLLSMAIKSARAKGKYVGICGQGPSDHP 757 IG+NDL Q T+ DR + V++L+ +PA+ +L+ M IK+A ++GK+VG+CG+ D Sbjct: 452 IGTNDLIQYTMAADRMNERVSYLYQPYHPAILRLVDMVIKAAHSEGKWVGMCGEMAGD-E 510 Query: 758 ELAEWLMQEGIESVSLNPDTVVDTWLRLAKLKSE 791 L+ G++ S++ +++ +L KL E Sbjct: 511 VAIPLLLGLGLDEFSMSATSILPARSQLLKLSKE 544
>BACTRLTOXIN#Bacterial toxin signature. Length = 266 Score = 28.3 bits (63), Expect = 0.012 Identities = 7/30 (23%), Positives = 14/30 (46%) Query: 73 YDLCDPVTGEPDPSAYVRLYRDARQAETTH 102 YD+ + D S Y+ +Y D + ++ Sbjct: 225 YDMMPAPGDKFDQSKYLMMYNDNKTVDSKS 254
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 101 bits (253), Expect = 4e-28 Identities = 72/255 (28%), Positives = 110/255 (43%), Gaps = 11/255 (4%) Query: 2 RSILITGAGSGIGAGLATVLAADGHHLLVSDADLAAAEQTTQQVRAAGGSAEALVLDVTD 61 + ITGA GIG +A LA+ G H+ D + E+ ++A AEA DV D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 62 EHSIAQALAAAARAPE---VLVNNAGLQHVAPLEEFPMQRWALLVDVMLTGAARLSRAVL 118 +I + A R +LVN AG+ + + W V TG SR+V Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 119 PGMRAGGYGRIVNIGSIHSLVASPYKSAYVAAKHGLIGLSKVLALETADCDITANTLCPS 178 M G IV +GS + V +AY ++K + +K L LE A+ +I N + P Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 179 YVRTPLVERQIADQARTRGIAEDAVIR---EVMLKPMPKGAFIEYDELAGTVAFLMSHAA 235 T + AD+ + VI+ E +P + ++A V FL+S A Sbjct: 189 STETDMQWSLWADEN-----GAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 236 RNLTGQAIAIDGGWT 250 ++T + +DGG T Sbjct: 244 GHITMHNLCVDGGAT 258
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 33.0 bits (75), Expect = 0.001 Identities = 12/88 (13%), Positives = 20/88 (22%) Query: 300 RGAQAKPAAASAPKPDAGPAPVAAASAPPRAAAQPTTPPEAAPAKRATRQTAAAPETSRP 359 + +P P+P V P P + + Sbjct: 72 PVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFEN 131 Query: 360 KASNTRPAAKKATKTSKSPARAPSGGKP 387 A ++ TSK SG + Sbjct: 132 TAPARPTSSTATAATSKPVTSVASGPRA 159 Score = 32.3 bits (73), Expect = 0.003 Identities = 14/77 (18%), Positives = 21/77 (27%), Gaps = 4/77 (5%) Query: 303 QAKPAAASAPKPDAGPAPVAAASAPPR----AAAQPTTPPEAAPAKRATRQTAAAPETSR 358 Q P P+P+ P P AP P ++ R Sbjct: 67 QPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPA 126 Query: 359 PKASNTRPAAKKATKTS 375 NT PA ++ + Sbjct: 127 SPFENTAPARPTSSTAT 143 Score = 28.4 bits (63), Expect = 0.046 Identities = 18/94 (19%), Positives = 28/94 (29%), Gaps = 5/94 (5%) Query: 297 RMLRGAQAKPAAASAPKPDAGPAPVAAASAPPRAAAQPTTPPEAAPAKRA----TRQTAA 352 + A A+P + + P P A PP +P PE P + Sbjct: 40 VIELPAPAQPISVTMVAPADLE-PPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPK 98 Query: 353 APETSRPKASNTRPAAKKATKTSKSPARAPSGGK 386 +PK K+ K +S +P Sbjct: 99 PKPKPKPKPVKKVEQPKRDVKPVESRPASPFENT 132
>PF04183#IucA / IucC family Length = 580 Score = 31.8 bits (72), Expect = 0.014 Identities = 23/129 (17%), Positives = 36/129 (27%), Gaps = 9/129 (6%) Query: 166 ARAILMERWGEDAALVGELRSWLNDNGVIRARVAEGKEEAGAKYR-DYFDHAESLARIPS 224 A L RW + V + L +G + E A + + Sbjct: 293 AAGPLASRWLQQ---VFATDATLVQSGAVILG-----EPAAGYVSHEGYAALARAPYRYQ 344 Query: 225 HRLLALFRARREEFLYLDLDPGTDADAGHQYAEGRVARSAGISNEGRPADRWLLDACRLT 284 L ++R +L D P A + A I G A+ WL R+ Sbjct: 345 EMLGVIWRENPCRWLKPDESPVLMATLMECDENNQPLAGAYIDRSGLDAETWLTQLFRVV 404 Query: 285 WRAKLHMHL 293 H+ Sbjct: 405 VVPLYHLLC 413
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 84.1 bits (208), Expect = 8e-19 Identities = 32/121 (26%), Positives = 57/121 (47%), Gaps = 4/121 (3%) Query: 1012 LDGVRLLLVDDDQDSREAVMHFLMLAGAQVQAAGSVDAAEAHLAAAHYDVLVSDIAMPLR 1071 + G +L+ DDD R + L AG V+ + +AA D++V+D+ MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 1072 DGYDLIRSVRSGRPELPRHIRAIALTAYVREEDRDRAIVAGFDAHMGKPVEPPGLIDLIE 1131 + +DL+ ++ RP+LP + ++A +A G ++ KP + LI +I Sbjct: 61 NAFDLLPRIKKARPDLPV----LVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116 Query: 1132 R 1132 R Sbjct: 117 R 117
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 41.4 bits (97), Expect = 2e-07 Identities = 23/119 (19%), Positives = 46/119 (38%), Gaps = 7/119 (5%) Query: 8 RVLVVENDDMNAMLLEMQLIQAGAAVVGPVGEVDDALQLIEADAPDTAVLDYRLGNGQTS 67 +LV ++D +L L +AG V + I A D V D + + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMP-DENA 62 Query: 68 EPVARRLTER--GIPFVLATGVAS-ASIPHGFERGVI--LTKPYMSDELVDALAKARQR 121 + R+ + +P ++ + + + E+G L KP+ EL+ + +A Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 55.6 bits (134), Expect = 1e-10 Identities = 41/242 (16%), Positives = 80/242 (33%), Gaps = 33/242 (13%) Query: 50 VETAKAARRAVAASYTGTAALEPRAEAQVVAKTSGVALAVMVEEGQKVSAGQALVRLDPD 109 + + Q +AK AV+ +E + V A L Sbjct: 220 LARINRYENLSRVEKSRLDDFSSLLHKQAIAK-----HAVLEQENKYVEAVNELRVYKSQ 274 Query: 110 RAHL--AVAQSEAQLRKLENSYRRATQLVGQQLVSA-ADVDQLKFDVENSRAQHRLASLE 166 + + ++ + + + ++ + +L ++ L + Sbjct: 275 LEQIESEILSAKEEYQLVTQLFKN---EILDKLRQTTDNIGLL-------TLELAKNEER 324 Query: 167 LSYTTVQAPISGVIASRSIKT-GNFVQINTPIFRIV-DDSQLEATLNVPERELATLKSGQ 224 + ++AP+S + + T G V + IV +D LE T V +++ + GQ Sbjct: 325 QQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQ 384 Query: 225 PVTLLADALPGQQF---VGKVDRIAP--VVDSGSGT-FRVVCAF-------GAGAEALQP 271 + +A P ++ VGKV I + D G F V+ + G L Sbjct: 385 NAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCLSTGNKNIPLSS 444 Query: 272 GM 273 GM Sbjct: 445 GM 446 Score = 44.4 bits (105), Expect = 5e-07 Identities = 16/74 (21%), Positives = 33/74 (44%), Gaps = 9/74 (12%) Query: 78 VVAKTSGVALAVMVEEGQKVSAGQALVRLDPDRAHLAVAQSEAQLRKLENSYR--RATQL 135 + + + ++V+EG+ V G L++L +EA K ++S R Q Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTA-------LGAEADTLKTQSSLLQARLEQT 151 Query: 136 VGQQLVSAADVDQL 149 Q L + ++++L Sbjct: 152 RYQILSRSIELNKL 165
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 651 bits (1680), Expect = 0.0 Identities = 259/1143 (22%), Positives = 479/1143 (41%), Gaps = 138/1143 (12%) Query: 22 LVAFATRRRVTIAMITVTMLLFGLIALRSLKVNLLPDLSYPTLTVRTEYTGAAPAEIETL 81 + F RR + ++ + +++ G +A+ L V P ++ P ++V Y GA ++ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 82 VTEPVEEAVGVVKNLRKLKSIS-RTGQSDVVLEFAWGTNMDQAGLEVRDKMEAL--SLPL 138 VT+ +E+ + + NL + S S G + L F GT+ D A ++V++K++ LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 139 EAKPPVLLRFNPSTEPIMRLVLSPKQAPASDTDAIRQLTGLRRYADEDLKKKLEPVAGVA 198 E + + S+ +M + + Y ++K L + GV Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFV-------SDNPGTTQDDISDYVASNVKDTLSRLNGVG 173 Query: 199 AVKVGGGLEDEIQVDIDQQKLAQLSLPIDNVITRLKEENVNISGGRL------EEGSQRY 252 V++ G + +++ +D L + L +VI +LK +N I+ G+L Sbjct: 174 DVQLFGA-QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNA 232 Query: 253 LVRTVNQFVDLDEIRNMLVTTQSSSSSAADAAMQQMYAIAASTGSQAALAAAAEVQSTSA 312 + +F + +E + + S Sbjct: 233 SIIAQTRFKNPEEFGKVTLRVNSD------------------------------------ 256 Query: 313 SSTSSIAGGMPVRLKDVAQVRQGYKEREAIIRLGGKEAVELAIYKEGDANTVSTAASLRK 372 G VRLKDVA+V G + I R+ GK A L I AN + TA +++ Sbjct: 257 --------GSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDTAKAIKA 308 Query: 373 RLEQIKATVPGDVEITTIEDQSHFIEHAISDVKKDAVIGGVLAILIIFLFLRDGWSTFVI 432 +L +++ P +++ D + F++ +I +V K +L L+++LFL++ +T + Sbjct: 309 KLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIP 368 Query: 433 SLSLPVSIITTFFFMGQLGLSLNVMSLGGLALATGLVVDDSIVVLESIAKA-RERGLSVL 491 ++++PV ++ TF + G S+N +++ G+ LA GL+VDD+IVV+E++ + E L Sbjct: 369 TIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPK 428 Query: 492 DAAMVGTREVSMAVMASTLTTIAVFLPLVFVEGIAGQLFRDQALTVAIAIAISLVVSMTL 551 +A ++ A++ + AVF+P+ F G G ++R ++T+ A+A+S++V++ L Sbjct: 429 EATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALIL 488 Query: 552 IPMLSSLKGAPPMAFPDEPSHPQWQPQQRWLKPVAAGRRGAGASVRYAFFGAAWAVVKAW 611 P L + LKPV+A + FFG Sbjct: 489 TPALCA----------------------TLLKPVSAEHHEN----KGGFFGWFNTT---- 518 Query: 612 RGATRVVAPVMRKASDIAMAPYGRAERGYLTMLPAALRRPWLVLGLAGAAFVGTVLLVPM 671 + + Y + L L + G V+L Sbjct: 519 ---------------------FDHSVNHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLR 557 Query: 672 LGADLIPQLAQDRFEMTVKLPSGTPLAQTDALVRELQ--LAHDKDPGIASLYGVSGAGTR 729 L + +P+ Q F ++LP+G +T ++ ++ ++ + S++ V+G Sbjct: 558 LPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNEKANVESVFTVNGFSF- 616 Query: 730 LDANPTESGENIGKLTVVMAG-----GGSPAVEAAATERLRSSMTAHPGAQV-DFARPAL 783 + +N G V + G + EA R + + V F PA+ Sbjct: 617 -----SGQAQNAGMAFVSLKPWEERNGDENSAEAVI-HRAKMELGKIRDGFVIPFNMPAI 670 Query: 784 FSF--STPLEVEL---RGQDLGELEQAGQKLAQMLRAN-GHYADVKSTVEEGFPEIQIRF 837 +T + EL G L QA +L M + V+ E + ++ Sbjct: 671 VELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEV 730 Query: 838 DQERAGALGLTTRQIADVIVKKVRGDVATRYSFRDRKIDVLVRAQHSDRASVDAIRQLIV 897 DQE+A ALG++ I I + G + R R + V+A R + + +L V Sbjct: 731 DQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRMLPEDVDKLYV 790 Query: 898 NPGSSRPVRLAAVAEVVATTGPSEIHRADQTRVAIVSASLR-DIDLGGAVREVETLVRND 956 + V +A G + R + + G A+ +E L Sbjct: 791 RSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASKL 850 Query: 957 PLAAGVGMHIGGQGEELAQSVKSLLFAFGLAIFLVYLVMASQFESLLHPFVILFTIPLAM 1016 P AG+G G + S ++ +V+L +A+ +ES P ++ +PL + Sbjct: 851 P--AGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGI 908 Query: 1017 VGAVLALLMTGKPVSVVVFIGLILLVGLVTKNAIILIDKVNQLRE-EGVAKREALIEGAR 1075 VG +LA + + V +GL+ +GL KNAI++++ L E EG EA + R Sbjct: 909 VGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVR 968 Query: 1076 SRLRPIIMTTLCTLFGFLPLAVAMGEGAEVRAPMAITVIGGLLVSTLLTLLVIPVVYDLL 1135 RLRPI+MT+L + G LPLA++ G G+ + + I V+GG++ +TLL + +PV + ++ Sbjct: 969 MRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVI 1028 Query: 1136 DRR 1138 R Sbjct: 1029 RRC 1031
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 547 bits (1412), Expect = 0.0 Identities = 228/1047 (21%), Positives = 441/1047 (42%), Gaps = 67/1047 (6%) Query: 3 VAAFSIRRPVTTIMCFVSLVVVGLIAAFRLPLEALPDISAPFLFVQLPYTGSTPDEVERN 62 +A F IRRP+ + + L++ G +A +LP+ P I+ P + V Y G+ V+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 63 LVRPAEEALATMTGIKRMRSTATADG-ANIFIEFSDWDRDIAIAASDARERLDAIRDDFP 121 + + E+ + + + M ST+ + G I + F D IA + +L P Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQS-GTDPDIAQVQVQNKLQLATPLLP 119 Query: 122 EDLQRFHIFKWSSSDEPVLKVRLAS---QADLTGAYDMLDREFKRRIERIPGVAKVEISG 178 +++Q+ I SS ++ S D + K + R+ GV V++ G Sbjct: 120 QEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG 179 Query: 179 APPNEVEIAIAPDRLTAHDLSLNDLSERLGKLNFSVSAGQI------DDNGQRIRVQPVG 232 A + I + D L + L+ D+ +L N ++AGQ+ + Sbjct: 180 AQ-YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQT 238 Query: 233 ELRDLQELRDLVLNAKG----LRLGDIAQVRLKPTRMNYGRRLDGRPAIGLDIYKERSAN 288 ++ +E + L +RL D+A+V L N R++G+PA GL I AN Sbjct: 239 RFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGAN 298 Query: 289 LVEVSKAALKEVEDIRAE-PAMRDVQVKVIDNQGKAVTSSLAELAEAGAVGLLLSITVLF 347 ++ +KA ++ +++ P ++V + V S+ E+ + ++L V++ Sbjct: 299 ALDTAKAIKAKLAELQPFFPQ--GMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMY 356 Query: 348 FFLRHWPSTLMVTLAIPICFAITLGFMYFVGVTLNILTMMGLLLAVGMLVDNAVVVVESI 407 FL++ +TL+ T+A+P+ T + G ++N LTM G++LA+G+LVD+A+VVVE++ Sbjct: 357 LFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENV 416 Query: 408 YQERERMPGQPQLAALLGTRSVAIALSAGTLCHCIVFVPNLFGETNNISIFMAQIAITIS 467 + P+ A + AL + VF+P + + Q +ITI Sbjct: 417 ERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIP-MAFFGGSTGAIYRQFSITIV 475 Query: 468 VSLLASWLVAISLIPMLSARMKTP----------PLVTSERGVIARLQRRYAKVLAWTLA 517 ++ S LVA+ L P L A + P Y + L Sbjct: 476 SAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILG 535 Query: 518 HRG-WSVAGILLVSAISLVPMKLTKVDMFGGDGGNEGYIQY--QWKGSYTREQLGDEIAR 574 G + + L+V+ + ++ ++L + D +G Q T+E + Sbjct: 536 STGRYLLIYALIVAGMVVLFLRLPSSFLPEED---QGVFLTMIQLPAGATQE----RTQK 588 Query: 575 VENHLEANRAKYHITQIYSWFSEV------EGSNTVVTFDATKVKDLPPLLEQIRKELPR 628 V + + K + S F+ + N + F + K + E + + Sbjct: 589 VLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIH 648 Query: 629 SARADYS---IGN---------QGDGGSGNQGVQVQ-LVGDSTQALQELADEVVPLLAQR 675 A+ + G G + ++ G AL + ++++ + AQ Sbjct: 649 RAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQH 708 Query: 676 -KELRDVRVDTGDRTSELAIRVDRERAAAFGFSAEQVASFVGLALRGTPLREFRRGDNEV 734 L VR + + T++ + VD+E+A A G S + + AL GT + +F Sbjct: 709 PASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVK 768 Query: 735 PVWVRFAGAEQSKPEDLAGFTVRTKDGRSVPLLSLVDVKIRPAATQIGRTNRQTTLTIKA 794 ++V+ + PED+ VR+ +G VP + + ++ R N ++ I+ Sbjct: 769 KLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQG 828 Query: 795 NLGTKVTVPEARAAMEQPLKAMQFPAGYSYTFDGGDYQDDGEAMGQMVFNLVIALVMIYV 854 + +A A ME + PAG Y + G + + Q + I+ V++++ Sbjct: 829 EAAPGTSSGDAMALMENLASKL--PAGIGYDW-TGMSYQERLSGNQAPALVAISFVVVFL 885 Query: 855 VMAAVFESLLFPAAIMSGVLFSIFGVFWLFWITGTSFGIMSFIGILVLMGVVVNNGIVMI 914 +AA++ES P ++M V I GV + + +G+L +G+ N I+++ Sbjct: 886 CLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIV 945 Query: 915 EHINNLRRR-GMGRTQALIEGSRERLRPIMMTMGTAILAMVPISLTSTTMFSDGPPYFPM 973 E +L + G G +A + R RLRPI+MT IL ++P+++++ + Sbjct: 946 EFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGA---GSGAQNAV 1002 Query: 974 ARAIAGGLAFSTVVSLLFLPTIYAILD 1000 + GG+ +T++++ F+P + ++ Sbjct: 1003 GIGVMGGMVSATLLAIFFVPVFFVVIR 1029
>PF06580#Sensor histidine kinase Length = 349 Score = 26.4 bits (58), Expect = 0.048 Identities = 15/120 (12%), Positives = 44/120 (36%), Gaps = 17/120 (14%) Query: 10 TWAIHPFHAAVLGGVLPLFLGALLSDYAYWSSYQIQWSNFASWLLVGAMVFTSIALLCGI 69 + P +++ + +G +L+ + W ++ + C + Sbjct: 32 SLYGSPKLHSMIFNIAISLMGLVLTHAYRSFIKRQGWLKLNMGQII-----LRVLPACVV 86 Query: 70 VGLVRGSRHVLYVVALVATWVIGFWNALHHARDAWAIMPMALVLSVIVTLLALLATWAGF 129 +G+ ++ VA + W + + ++ A+ + L LS+I ++ + W+ Sbjct: 87 IGM-------VWFVANTSIWRLLAF--INTKPVAFT---LPLALSIIFNVVVVTFMWSLL 134
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 37.5 bits (87), Expect = 5e-05 Identities = 15/75 (20%), Positives = 29/75 (38%), Gaps = 9/75 (12%) Query: 184 VLVVDDSRVARQQIRSVLDQLGVAATLLSDGRQALDHLLQVAASGENPAERYAMVISDIE 243 +LV DD R + L + G + S+ + A +V++D+ Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIA---------AGDGDLVVTDVV 56 Query: 244 MPAMDGYTLTTEIRR 258 MP + + L I++ Sbjct: 57 MPDENAFDLLPRIKK 71
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 45.3 bits (107), Expect = 3e-07 Identities = 25/67 (37%), Positives = 37/67 (55%), Gaps = 3/67 (4%) Query: 4 NTSLSGINAANADLNVTSNNIANVNTTGFKESRAEFADMFQSTSYGLSRNAVGSGVRVSN 63 N ++SG+NAA A LN SNNI++ N G+ A Q+ S + VG+GV VS Sbjct: 5 NNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMA---QANSTLGAGGWVGNGVYVSG 61 Query: 64 VAQQFSQ 70 V +++ Sbjct: 62 VQREYDA 68 Score = 42.6 bits (100), Expect = 2e-06 Identities = 17/65 (26%), Positives = 33/65 (50%) Query: 343 TSGAARVGAPDTSDLGQIESGSLEASTVDLTEQLVNMIVAQRNFQANSQMISTQDQVTQT 402 T+ A + + Q+ + S V+L E+ N+ Q+ + AN+Q++ T + + Sbjct: 482 TATLKTSSATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDA 541 Query: 403 IINIR 407 +INIR Sbjct: 542 LINIR 546
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 30.3 bits (68), Expect = 0.008 Identities = 9/31 (29%), Positives = 19/31 (61%) Query: 5 LYVAMTGARASLQAQSTVSHNLANVDTVGFK 35 + AM+G A+ A +T S+N+++ + G+ Sbjct: 4 INNAMSGLNAAQAALNTASNNISSYNVAGYT 34
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 39.2 bits (91), Expect = 1e-05 Identities = 12/41 (29%), Positives = 20/41 (48%) Query: 219 LEGSNVNTVEELVSMIETQRAYEMNAKAISTTDSMLGYLNN 259 S VN EE ++ Q+ Y NA+ + T +++ L N Sbjct: 504 QSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALIN 544 Score = 37.6 bits (87), Expect = 3e-05 Identities = 19/82 (23%), Positives = 31/82 (37%), Gaps = 20/82 (24%) Query: 5 LWVAKTGLDAQQTRMSVISNNLANTNTTGFKRDRAAFEDLLYQQVRAPGGSTSAQTQLPT 64 + A +GL+A Q ++ SNN+++ N G+ R T T Sbjct: 4 INNAMSGLNAAQAALNTASNNISSYNVAGYTRQT-----------------TIMAQANST 46 Query: 65 ---GLQLGTGVRVVSTFKGFDQ 83 G +G GV V + +D Sbjct: 47 LGAGGWVGNGVYVSGVQREYDA 68
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 142 bits (359), Expect = 3e-44 Identities = 76/196 (38%), Positives = 111/196 (56%), Gaps = 9/196 (4%) Query: 39 VPVVAPVAQPTAGAIYAAGPSLN-----LYGDRRARDVGDLLTVNLVENTTASSTANTSI 93 VP PVA G+I+ + +N L+ DRR R++GD LT+ L EN +AS +++ + Sbjct: 40 VPGPTPVA---NGSIFQSAQPINYGYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANA 96 Query: 94 SKADTVDMSTPTLLGVPLTVNGIDVLRNSTSGDRSFDGKGNTAQSNRMQGSVTVTVMQRL 153 S+ + T+ + G SG +F+GKG SN G++TVTV Q L Sbjct: 97 SRDGKTNFGFDTVPRYLQGLFGNARADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVL 156 Query: 154 PNGNLVIQGQKNLRLTQGDELVQVQGIVRAADIAPDNSVPSSKVADARIAYGGRGAIAQS 213 NGNL + G+K + + QG E ++ G+V I+ N+VPS++VADARI Y G G I ++ Sbjct: 157 VNGNLHVVGEKQIAINQGTEFIRFSGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEA 216 Query: 214 NAMGWLSRFFNSRLSP 229 MGWL RFF + LSP Sbjct: 217 QNMGWLQRFFLN-LSP 231
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 366 bits (940), Expect = e-128 Identities = 157/364 (43%), Positives = 221/364 (60%), Gaps = 9/364 (2%) Query: 10 LLAAAVALCAIAAPASAERIKDLAQVGGVRGNALVGYGLVVGLDGSGDRTSQAPFTVQSL 69 + +A L A A RIKD+A + R N L+GYGLVVGL G+GD +PFT QS+ Sbjct: 12 VFSALPFLSTPPAQADTSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFTEQSM 71 Query: 70 KNLLGELGVNVPANVNPQLKNVAAVAIHAELPPFAKPGQPIDITVSSIANAVSLRGGSLL 129 + +L LG+ KN+AAV + A LPPFA PG +D+TVSS+ +A SLRGG+L+ Sbjct: 72 RAMLQNLGITTQGG-QSNAKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRGGNLI 130 Query: 130 MAPLKGADGQVYAMAQGNLVVGGFGAQGKDGSRVSVNIPSVGRIPNGATVERALPDVFAG 189 M L GADGQ+YA+AQG L+V GF AQG D + ++ + + R+PNGA +ER LP F Sbjct: 131 MTSLSGADGQIYAVAQGALIVNGFSAQG-DAATLTQGVTTSARVPNGAIIERELPSKFKD 189 Query: 190 SGEITLNLHQNDFTTVSRMVAAIDN----SFGAGTARAVDGVTVSVRSPTDPSARIGLLA 245 S + L L DF+T R+ ++ +G A D ++V+ P + L+A Sbjct: 190 SVNLVLQLRNPDFSTAVRVADVVNAFARARYGDPIAEPRDSQEIAVQKP-RVADLTRLMA 248 Query: 246 RLENVELSPGDAPAKVVVNARTGTVVIGQLVRVMPAAIAHGSLTVTISENTNVSQPGAFS 305 +EN+ + D PAKVV+N RTGT+VIG VR+ A+++G+LTV ++E+ V QP FS Sbjct: 249 EIENLTVET-DTPAKVVINERTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQPAPFS 307 Query: 306 GGRTAVTPQSTIKATSEGSRMFKFEGGTTLDQIVRAVNEVGAAPGDLVAILEALKQAGAL 365 G+TAV PQ+ I A EGS++ E G L +V +N +G ++AIL+ +K AGAL Sbjct: 308 RGQTAVQPQTDIMAMQEGSKVAIVE-GPDLRTLVAGLNSIGLKADGIIAILQGIKSAGAL 366 Query: 366 TAEL 369 AEL Sbjct: 367 QAEL 370
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 130 bits (327), Expect = 7e-37 Identities = 63/140 (45%), Positives = 82/140 (58%), Gaps = 4/140 (2%) Query: 221 FVAKIWTHAQKAARELGVDPRALVAQAALETGWGRRGI--GNGGDSNNLFGIKATG-WNG 277 F+A++ AQ A+++ GV ++AQAALE+GWG+R I NG S NLFG+KA+G W G Sbjct: 152 FLAQLSLPAQLASQQSGVPHHLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKG 211 Query: 278 AKVTTGTHEYVNGVKTTETADFRAYGSAEESFADYVRLLKNNSRYQTALQAGTDIKGFAR 337 T EY NG A FR Y S E+ +DYV LL N RY A+ + A+ Sbjct: 212 PVTEITTTEYENGEAKKVKAKFRVYSSYLEALSDYVGLLTRNPRY-AAVTTAASAEQGAQ 270 Query: 338 GLQQAGYATDPGYAAKIAAI 357 LQ AGYATDP YA K+ + Sbjct: 271 ALQDAGYATDPHYARKLTNM 290 Score = 72.1 bits (176), Expect = 3e-16 Identities = 44/121 (36%), Positives = 65/121 (53%), Gaps = 15/121 (12%) Query: 19 AKIDKVSRQLEGQFAQMLVKSMRDASSGDPMFPGENQ-MFREMYDQQMAKALTDGKGLGL 77 A I V+RQ+EG F QM++KSMRDA D +F E+ ++ MYDQQ+A+ +T GKGLGL Sbjct: 31 ANIRPVARQVEGMFVQMMLKSMRDALPKDGLFSSEHTRLYTSMYDQQIAQQMTAGKGLGL 90 Query: 78 SAMISKQLSGDTGGPA-------LNTSLSTADAAKAYALVAGKR-------DASLPLPAR 123 + M+ KQ++ + P + L T + AL + D SLP ++ Sbjct: 91 AEMMVKQMTPEQPLPEESTPAAPMKFPLETVVRYQNQALSQLVQKAVPRNYDDSLPGDSK 150 Query: 124 D 124 Sbjct: 151 A 151
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 229 bits (585), Expect = 1e-69 Identities = 150/441 (34%), Positives = 223/441 (50%), Gaps = 16/441 (3%) Query: 2 SIMSTGTSALIAFQRALSTVSHNVANINTEGYSRQRVEFATRTPTDMGYAFVGNGAKISD 61 S+++ S L A Q AL+T S+N+++ N GY+RQ A T +VGNG +S Sbjct: 2 SLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVSG 61 Query: 62 VGRVADQLAISRLL----DSGGELSRLQQLSSLSNRVDSLYSNTATNVAGLWSNFFDSAS 117 V R D ++L S G +R +Q+S + N + + S+ AT + +FF S Sbjct: 62 VQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQM----QDFFTSLQ 117 Query: 118 ALSSNASSTAERQSMLDSGNSLATRFKQLNGQMDSLSNEVNSGLTSSVDEVNRLTQQIAK 177 L SNA A RQ+++ L +FK + + +VN + +SVD++N +QIA Sbjct: 118 TLVSNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIAS 177 Query: 178 INGTI----GNSIDNASADLLDQRDALVSKLVGYTGGTAVIQDGGFMNVFTAGGQALVVG 233 +N I G + +LLDQRD LVS+L G +QDGG N+ A G +LV G Sbjct: 178 LNDQISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQG 237 Query: 234 TTAAKLTTVADPYQPTKLQVAMQTQGQNVSLSPSSL--GGQIGGLLEFRSNVLEPTQAEL 291 +TA +L V P++ VA P L G +GG+L FRS L+ T+ L Sbjct: 238 STARQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTL 297 Query: 292 GRLAVGMASSFNTAHSQGMDLYGALGGNFFNIGSPTTAANPKNTGTAALTASFSNLGAVD 351 G+LA+ A +FNT H G D G G +FF IG P N KN G A+ A+ ++ AV Sbjct: 298 GQLALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGDVAIGATVTDASAVL 357 Query: 352 GQNVTLSFDAGSWKATRTDTGSTVPLTGTGTAADPLVVNGVSMVVGGAPANGDKFLLQPT 411 + +SFD W+ TR + +T T T A + +G+ + G PA D F L+P Sbjct: 358 ATDYKISFDNNQWQVTRLASNTT--FTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPV 415 Query: 412 AGLAGSLSVAITDPSRIAAAT 432 + ++ V ITD ++IA A+ Sbjct: 416 SDAIVNMDVLITDEAKIAMAS 436 Score = 79.6 bits (196), Expect = 9e-18 Identities = 36/105 (34%), Positives = 56/105 (53%) Query: 517 AGSSDNGNAKLLAKVEDAKALNGGTVTLNGALSGLTTSVGSAARAANYAADAQEVINDQA 576 AG SDN N + L ++ GG + N A + L + +G+ ++ Q + Q Sbjct: 440 AGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGNKTATLKTSSATQGNVVTQL 499 Query: 577 QASRDSISGVNLDEEAADMLKLQQAYQAAAQMISTADTIFQAILG 621 + SISGVNLDEE ++ + QQ Y A AQ++ TA+ IF A++ Sbjct: 500 SNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALIN 544
>FLAGELLIN#Flagellin signature. Length = 507 Score = 52.7 bits (126), Expect = 1e-09 Identities = 59/350 (16%), Positives = 110/350 (31%), Gaps = 8/350 (2%) Query: 4 RISTSMMYSQSVSAMTAKQSRLNQLEAQLSSGQRLVTAKDDPVAAGTAVGLDRALAAITR 63 I+T+ + + + + QS L+ +LSSG R+ +AKDD A + +T+ Sbjct: 3 VINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQ 62 Query: 64 FGENANNVQNRLGLQENALAQAGDKMARVTELAVQSNNSSLSPDDRKAIASELTALRDSM 123 NAN+ + E AL + + + RV EL+VQ+ N + S D K+I E+ + + Sbjct: 63 ASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEEI 122 Query: 124 VSLANSTDGTGRYLFAGTADGNAPFIKSNGN----VLYNGDQTQRQVEVAPDTFVSDTLP 179 ++N T G + + + +N + + + Sbjct: 123 DRVSNQTQFNGVKVLSQDN-QMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKEAT 181 Query: 180 GSEIFMRIRTGDGSVDAHANATNTGTGLLLDFSRDASSGSWNGGSYSVQFTAADTYEVRD 239 ++ + G A + ++ V Sbjct: 182 VGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTDDA 241 Query: 240 STNALVSTGTYKDG--GDINAAGVRMRISGAPAVGDSFQIGASGTKDVFSTID-DMVAAL 296 N V G A + I G G + T D + D + + Sbjct: 242 ENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGNGKVST 301 Query: 297 NSDTQTPTQKAAMINTLQSSMRDIAQASSKMIDARASGGAQLSAIDNANS 346 + + T A I +++ SSK + G N Sbjct: 302 TINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNE 351 Score = 31.2 bits (70), Expect = 0.007 Identities = 48/269 (17%), Positives = 80/269 (29%), Gaps = 1/269 (0%) Query: 127 ANSTDGTGRYLFAGTADGNAPFIKSNGNVLYNGDQTQRQVEVAPDTFVSDTLPGSEIFMR 186 AN T D + G + DTF + + Sbjct: 232 ANGQLTTDDAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKT 291 Query: 187 IRTGDGSVDAHANATNTGTGLLLDFSRDASSGSWNGGSYSVQFTAADTYEVRDSTNALVS 246 G+G V N + + A+ + S +T+ + Sbjct: 292 GNDGNGKVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNE 351 Query: 247 TGTYKDGGDINAAGVRMRISGAPAVGDSFQIGASGTKDVFSTIDDMVAALNSDTQTPTQK 306 + D NA +I+ A + G T + D A T Sbjct: 352 SAKLSDLEANNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFID-KTASGVSTLINEDA 410 Query: 307 AAMINTLQSSMRDIAQASSKMIDARASGGAQLSAIDNANSLLESNEVTLKTTLSSIRDLD 366 AA + + + I A SK+ R+S GA + D+A + L + L + S I D D Sbjct: 411 AAAKKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDAD 470 Query: 367 YASAIGQYELERASLQAAQTIFQQMQSSS 395 YA+ + + QA ++ Q Sbjct: 471 YATEVSNMSKAQILQQAGTSVLAQANQVP 499
>FLAGELLIN#Flagellin signature. Length = 507 Score = 126 bits (318), Expect = 3e-34 Identities = 117/412 (28%), Positives = 168/412 (40%), Gaps = 18/412 (4%) Query: 2 AQVINTNVMSLNAQRNLNTNSSSMALSIQQLSSGKRITSASVDAAGLAISERFTTQIRGL 61 AQVINTN +SL Q NLN + SS++ +I++LSSG RI SA DAAG AI+ RFT+ I+GL Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 DVASRNANDGISLAQTAEGAMVEIGNNLQRIRELSVQSANATNSATDREALNSEVKQLTS 121 ASRNANDGIS+AQT EGA+ EI NNLQR+RELSVQ+ N TNS +D +++ E++Q Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 EIDRVANQTSFNGTKLLNGDFSGALFQVGADAGQTIGI-----------------NSIVD 164 EIDRV+NQT FNG K+L+ D QVGA+ G+TI I N + Sbjct: 121 EIDRVSNQTQFNGVKVLSQDNQ-MKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKE 179 Query: 165 ANVDSLGKANFAASVSGAGVTGAATASGSLSGITLAFKDASGAAKSVAVADIKIASGDTA 224 A V L + + GA ++ + + + T Sbjct: 180 ATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTD 239 Query: 225 ADINKKVASAINDKLDQTGMYASIDTSGNVKLESLKAGQDFTSLSGGTSGAAGITAGAGI 284 N G + +G +K D+ ++ G + Sbjct: 240 DAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGNGKV 299 Query: 285 QTASAASGSTASTLSSLDISTFSGAQKALEIVDKALTSVNSSRADMGAVQNRFTSTIANL 344 T T + + A + + VN +N Sbjct: 300 STTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSDLE 359 Query: 345 AATSENLTASRSRIADTDYAKTTAELTRTRTQILQQAGTAMLAQAKSVPQNV 396 A + + + A + + + TA Sbjct: 360 ANNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINEDAA 411 Score = 87.8 bits (217), Expect = 6e-21 Identities = 71/342 (20%), Positives = 126/342 (36%), Gaps = 5/342 (1%) Query: 60 GLDVASRNANDGISLAQTAEGAMVEIGNNLQRIRELSVQSANATNSATDREALNSEVKQL 119 G +V L + + + + ++ A + T + +V Sbjct: 171 GFNVNGPKEATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVN 230 Query: 120 TSEIDRVANQTSFNGTKLLNGDFSGALFQVGADAGQTIGINSIVDANVDSLGKANFAASV 179 + + N L A A D G + Sbjct: 231 AANGQLTTDDAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTK 290 Query: 180 SGAGVTGAATASGSLSGITLAFKDASGAAKSVAVADIKIASGDTAADINKKVASAINDKL 239 +G G + + + +TL D + A +V A ++ + + +N + K Sbjct: 291 TGNDGNGKVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKN 350 Query: 240 DQTGMYASIDTSGNVKLESLKAGQDFTSLSGGTSGAAGITAGAGIQTASAASGSTASTLS 299 + + + + + + +T + ++ ++ Sbjct: 351 ESAKLSDLEANNAVKGESKITVN---GAEYTANAAGDKVTLAGKTMFIDKTASGVSTLIN 407 Query: 300 SLDISTFSGAQKALEIVDKALTSVNSSRADMGAVQNRFTSTIANLAATSENLTASRSRIA 359 + L +D AL+ V++ R+ +GA+QNRF S I NL T NL ++RSRI Sbjct: 408 EDAAAAKKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIE 467 Query: 360 DTDYAKTTAELTRTRTQILQQAGTAMLAQAKSVPQNVLSLLQ 401 D DYA + + ++ QILQQAGT++LAQA VPQNVLSLL+ Sbjct: 468 DADYATEVSNM--SKAQILQQAGTSVLAQANQVPQNVLSLLR 507
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 70.6 bits (173), Expect = 2e-16 Identities = 34/160 (21%), Positives = 66/160 (41%), Gaps = 9/160 (5%) Query: 2 RVIIVDDHTLVRAGLSRLLQTFSGIDVVGEASNAQQALDMTSLHRPDLVLMDLSLPGRSG 61 +++ DD +R L++ L + +G DV SNA + DLV+ D+ +P + Sbjct: 5 TILVADDDAAIRTVLNQAL-SRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 62 LDAMTDVLRAAPRTHVVMMSMHDDPVHVRDALDRGAVGFVVKDAAPLELELALRAAAAGQ 121 D + + +A P V++MS + + A ++GA ++ K EL + A Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA---- 118 Query: 122 VFLSPQISSKMIAPMLGREKPVGIAALSPRQREILREIGR 161 + + + + + S +EI R + R Sbjct: 119 ---LAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLAR 155
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 71.0 bits (174), Expect = 1e-15 Identities = 32/175 (18%), Positives = 64/175 (36%), Gaps = 20/175 (11%) Query: 104 LTRLASERAQVQAEIAAIQQSRAVAGIDVERSRQLLAEGLAGRRDYELTQIKVAEADAKL 163 +E ++++ I+ A + + QL K+ + + Sbjct: 261 YVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLF---------KNEILDKLRQTTDNI 311 Query: 164 AESRAKLTRIDIQLNRQSAQLVRAPRDGRVQQLNAASGSAMVSPGTVLAVIAPERVERAV 223 +L + + + ++RAP +VQQL + +V+ L VI PE V Sbjct: 312 GLLTLELAKNEERQQAS---VIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEV 368 Query: 224 ELYIDGRDVPLIRPGRPVRLEFEGWPAIQFSGWPSVAHGMFDGRVRAIDPNAAPD 278 + +D+ I G+ I+ +P +G G+V+ I+ +A D Sbjct: 369 TALVQNKDIGFINVGQNAI--------IKVEAFPYTRYGYLVGKVKNINLDAIED 415 Score = 67.5 bits (165), Expect = 2e-14 Identities = 29/207 (14%), Positives = 73/207 (35%), Gaps = 20/207 (9%) Query: 5 ADRNAHFPT-LAAMRPPSIAKA--LAWMLLIGVAIAAAILALAPWVQTASGKGQVVSLDP 61 D N P L + P + +A+ ++ + IA + L A+ G++ Sbjct: 36 KDENEFLPAHLELIETPVSRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLT---H 92 Query: 62 GDRQQQVTAFVPGRVETWYVHDGQHVSRGDPIARVGDLDPDLLTRLASERAQVQAEIAAI 121 R +++ V+ V +G+ V +GD + ++ L + + Q A + Sbjct: 93 SGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALG----AEADTLKTQSSLLQARL 148 Query: 122 QQSRAVAGIDVERSRQLLAEGLAGRRDYELTQIKVAEADAKLAES-----RAKLTRIDIQ 176 +Q+R +L L ++ + L + + + + ++ Sbjct: 149 EQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELN 208 Query: 177 LNRQSAQLVRAPRDGRVQQLNAASGSA 203 L+++ A+ + ++N + Sbjct: 209 LDKKRAER-----LTVLARINRYENLS 230
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 37.1 bits (86), Expect = 1e-04 Identities = 27/197 (13%), Positives = 62/197 (31%), Gaps = 24/197 (12%) Query: 287 RAVLTRIDQATARLMLAQNDLKPRLDVSFEVSKDLGAPGVGGPNRSPTDAIIGFRFSVPL 346 + R++Q +++ +L ++ + V ++I +FS Sbjct: 142 SLLQARLEQTRYQILSRSIELNKLPELKL--PDEPYFQNVSEEEVLRLTSLIKEQFST-W 198 Query: 347 ENRSAKGRV--AEARAEIEALDQRSRFLRDQISVEVESIVISLNAAQRLAG--------I 396 +N+ + + + RAE + R + VE L+ L + Sbjct: 199 QNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSR----LDDFSSLLHKQAIAKHAV 254 Query: 397 ADEERSLAD---RLAAAERRRFELGSG----DFFLVNQREETANDARVRLIDAQARIASA 449 ++E + L + + ++ S + N+ +L I Sbjct: 255 LEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLL 314 Query: 450 RAELAAATADRDALMLR 466 ELA + A ++R Sbjct: 315 TLELAKNEERQQASVIR 331
>PF04183#IucA / IucC family Length = 580 Score = 32.5 bits (74), Expect = 0.002 Identities = 18/95 (18%), Positives = 30/95 (31%), Gaps = 11/95 (11%) Query: 106 SLANGEAFADWLEQTLPQAPQLRYCLDPVIGDTHTGPYVEPGLERVFAERLLPHAWLVTP 165 +A G + WL+Q L ++G+ G G A P+ + Sbjct: 291 YIAAGPLASRWLQQVFATDATLVQSGAVILGEPAAGYVSHEGYA---ALARAPYRY---- 343 Query: 166 NAFELG---RLTGLPSLEQDDAIVAARALLARGPQ 197 LG R L+ D++ V L+ Sbjct: 344 -QEMLGVIWRENPCRWLKPDESPVLMATLMECDEN 377
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 139 bits (351), Expect = 2e-38 Identities = 81/392 (20%), Positives = 145/392 (36%), Gaps = 91/392 (23%) Query: 5 IGIDLGTTNSCVAIMDGGKARVIENSEGDRTTPSIVAYTKDGE------VLVGASAKRQA 58 + IDLGT N+ + + G + E PS+VA +D VG AK+ Sbjct: 13 LSIDLGTANTLIYVKGQGIV-LNE--------PSVVAIRQDRAGSPKSVAAVGHDAKQML 63 Query: 59 VTNPKNTFYAVKRLIGRKFTDGEVQKDISHVPYGILAHDNGDAWVQTSDSKRMAPQEISA 118 P N A++ + KD + + +++ Sbjct: 64 GRTPGN-IAAIRPM-----------KDGVIADFFV-------------------TEKMLQ 92 Query: 119 RVLEKMKKTAEDFLGEKVTEAVITVPAYFNDSQRQATKDAGRIAGLDVKRIINEPTAAAL 178 ++++ + ++ VP +R+A +++ + AG +I EP AAA+ Sbjct: 93 HFIKQVHS---NSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAI 149 Query: 179 AYGLDKNGGDRKIAVYDLGGGTFDVSIIEIAEVDGEKQFEVLATNGDTFLGGEDFDNRVI 238 GL + V D+GGGT +V++I + V + +GG+ FD +I Sbjct: 150 GAGLPVS-EATGSMVVDIGGGTTEVAVISLNGV---------VYSSSVRIGGDRFDEAII 199 Query: 239 EYLVDEFNKDQGIDLRKDPLALQRLKDAAERAKIELSTS----QQTEVNLPYVTADASGP 294 Y+ + G + AER K E+ ++ + E+ + P Sbjct: 200 NYVRRNYGSLIG-------------EATAERIKHEIGSAYPGDEVREIEVRGRNLAEGVP 246 Query: 295 KHLNIKLTRAKLEALVE------DLVKKSIEPCRTALNDAGLRASDINE--VILVGGQTR 346 + + + LEAL E V ++E C L ASDI+E ++L GG Sbjct: 247 RGFTLN-SNEILEALQEPLTGIVSAVMVALEQCPPEL------ASDISERGMVLTGGGAL 299 Query: 347 MPKVQQAVADFFGKEPRKDVNPDEAVAVGAAI 378 + + + + + G +P VA G Sbjct: 300 LRNLDRLLMEETGIPVVVAEDPLTCVARGGGK 331
>AEROLYSIN#Aerolysin signature. Length = 493 Score = 25.4 bits (55), Expect = 0.026 Identities = 14/36 (38%), Positives = 18/36 (50%), Gaps = 1/36 (2%) Query: 7 RYQLSCNALPHPAQGWRADWRIQQVGASKAGD-LAR 41 RYQ +P + W +W IQQ G S + LAR Sbjct: 379 RYQWDKRYIPGEVKWWDWNWTIQQNGLSTMQNNLAR 414
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 93.2 bits (231), Expect = 6e-25 Identities = 60/200 (30%), Positives = 88/200 (44%), Gaps = 15/200 (7%) Query: 5 KIALVTGGTRGIGLETVRQLAQAGVHTLLAGRKRDDAVAAALKLQAEGLPVEAIQLDVND 64 KIA +TG +GIG R LA G H + L+AE EA DV D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 65 DISIAAAVGTVEQRHGHLDILINNAGIMIEDMQRKPSEQ-SLDTWKRTFDTNLFAVVGVT 123 +I +E+ G +DIL+N AG+ ++ S + W+ TF N V + Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGV----LRPGLIHSLSDEEWEATFSVNSTGVFNAS 124 Query: 124 KAFLPLLRRSLAGRIVNVSSILGSLTLHTQQGSPIYDFKIPAYDASKSALNSWTVHLAHE 183 ++ + +G IV +GS + S + AY +SK+A +T L E Sbjct: 125 RSVSKYMMDRRSGSIV----TVGSNPAGVPRTS------MAAYASSKAAAVMFTKCLGLE 174 Query: 184 LRESAIKVNMVHPGYVKTDM 203 L E I+ N+V PG +TDM Sbjct: 175 LAEYNIRCNIVSPGSTETDM 194
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1037 bits (2684), Expect = 0.0 Identities = 437/1041 (41%), Positives = 637/1041 (61%), Gaps = 20/1041 (1%) Query: 4 SRFFIDRPIFAAVLSIIIFAAGLIAMPLLPISEYPEVVPPSVQVRAVYPGANPKVIAETV 63 + FFI RPIFA VL+II+ AG +A+ LP+++YP + PP+V V A YPGA+ + + +TV Sbjct: 2 ANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTV 61 Query: 64 ATPLEEAINGVENMMYMKSVAGSDGVLVVTVTFKPGTDPDQAQVQVQNRVSQAQARLPED 123 +E+ +NG++N+MYM S + S G + +T+TF+ GTDPD AQVQVQN++ A LP++ Sbjct: 62 TQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE 121 Query: 124 VRRQGVTTQKQSPTLTMVVHLTSPKGKYDSLYLSNYATLKVKDELSRLPGVGQIQIFGAG 183 V++QG++ +K S + MV S +S+Y VKD LSRL GVG +Q+FG Sbjct: 122 VQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG-A 180 Query: 184 DYAMRIWLDPDKVAARGLTASDVVAAIREQNVQVSAGQLGAEPMPNKSEFLLSINAQGRL 243 YAMRIWLD D + LT DV+ ++ QN Q++AGQLG P + SI AQ R Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 244 TTEEEFGNIVIRSGTSGEIVRLSDVARLELGAGKYTLRSQLDSKSAVGMGVFQSPGANAI 303 EEFG + +R + G +VRL DVAR+ELG Y + ++++ K A G+G+ + GANA+ Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 304 ELSDAVRAKMAELEKQFPQDMAWSAAYDPTIFVRDSIKAVVSTLLEAVLLVVLVVILFLQ 363 + + A++AK+AEL+ FPQ M YD T FV+ SI VV TL EA++LV LV+ LFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 364 TWRASIIPLLAVPVSVVGTFAALYVLGFSINTLTLFGLVLAIGIVVDDAIVVVENVER-N 422 RA++IP +AVPV ++GTFA L G+SINTLT+FG+VLAIG++VDDAIVVVENVER Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 423 IEEGLSPLAAAHQAMREVSGPIIAIALVLCAVFVPMAFLSGVTGQFYKQFAVTIAISTVI 482 +E+ L P A ++M ++ G ++ IA+VL AVF+PMAF G TG Y+QF++TI + + Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 483 SAINSLTLSPALAAMLLKAHDAPKDGPTRLIDRLFGWIFRPFNRFFNTSSHKYQGAVSRA 542 S + +L L+PAL A LLK FGW FN F+ S + Y +V + Sbjct: 481 SVLVALILTPALCATLLKPV---SAEHHENKGGFFGW----FNTTFDHSVNHYTNSVGKI 533 Query: 543 LGKRGMVFMVYLLLLVGTGVMFKLVPGGFIPTQDKLYLIAGAKLPEGASLERTSEVISQI 602 LG G ++Y L++ G V+F +P F+P +D+ + +LP GA+ ERT +V+ Q+ Sbjct: 534 LGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQV 593 Query: 603 SDIALQTE--GVAHAVAFPGLNPLQFTNTPNTGTLFLTLKPFSERSR---TAAQINAEIN 657 +D L+ E V G + N G F++LKP+ ER+ +A + Sbjct: 594 TDYYLKNEKANVESVFTVNGFSFS--GQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAK 651 Query: 658 ARISQIEKGFAFAFMPPPILGLGQGSGYSLYIQDRAGLGYGQLQTAVTAMSGAISQTPG- 716 + +I GF F P I+ LG +G+ + D+AGLG+ L A + G +Q P Sbjct: 652 MELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPAS 711 Query: 717 MQFPIGTYQANVPQLDAKVDRDKAKAQGVPLTNVFDTLQTYLGSAYINDFNRFGRTYQVI 776 + + Q +VD++KA+A GV L+++ T+ T LG Y+NDF GR ++ Sbjct: 712 LVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLY 771 Query: 777 AQADGQFRDSVEDIANLRTRNDRGQMVPIGSMVTLGQTYGPDPVIRYNGYPAADLIGEAD 836 QAD +FR ED+ L R+ G+MVP + T YG + RYNG P+ ++ GEA Sbjct: 772 VQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAA 831 Query: 837 TRVLSSAQAMQTLAGMAPKVLPNGMNIEWTDLSYQQSIQGNSALIVFPMAVLLAFLVLAA 896 SS AM + +A K LP G+ +WT +SYQ+ + GN A + ++ ++ FL LAA Sbjct: 832 PGT-SSGDAMALMENLASK-LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAA 889 Query: 897 LYESWTLPLAVILIVPMTLLSALFGVWLTGGDNNVFVQVGLVVLMGLACKNAILIVEFAR 956 LYESW++P++V+L+VP+ ++ L L N+V+ VGL+ +GL+ KNAILIVEFA+ Sbjct: 890 LYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAK 949 Query: 957 EL-EMHGKGIVEAALEACRLRLRPIVMTSIAFIAGTVPLVFGHGAGAEVRSVTGITVFAG 1015 +L E GKG+VEA L A R+RLRPI+MTS+AFI G +PL +GAG+ ++ GI V G Sbjct: 950 DLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGG 1009 Query: 1016 MLGVTLFGLFLTPVFYVALRK 1036 M+ TL +F PVF+V +R+ Sbjct: 1010 MVSATLLAIFFVPVFFVVIRR 1030 Score = 86.8 bits (215), Expect = 2e-19 Identities = 72/328 (21%), Positives = 124/328 (37%), Gaps = 19/328 (5%) Query: 735 VDRDKAKAQGVPLTNVFDTLQTY---LGSAYIND-FNRFGRTYQVIAQADGQFRDSVEDI 790 +D D + +V + L+ + + + G+ A +F+ + E+ Sbjct: 188 LDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK-NPEEF 246 Query: 791 ANLRTR-NDRGQMVPIGSMVTLGQTYGPDPVI-RYNGYPAADLI----GEADTRVLSSAQ 844 + R N G +V + + + VI R NG PAA L A+ + A Sbjct: 247 GKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDTAKA- 305 Query: 845 AMQTLAGMAPKVLPNGMNIEWT-DLSY--QQSIQGNSALIVFPMAVLLAFLVLAALYESW 901 LA + P P GM + + D + Q SI + A++L FLV+ ++ Sbjct: 306 IKAKLAELQP-FFPQGMKVLYPYDTTPFVQLSIHEVVKTLF--EAIMLVFLVMYLFLQNM 362 Query: 902 TLPLAVILIVPMTLLSALFGVWLTGGDNNVFVQVGLVVLMGLACKNAILIVE-FARELEM 960 L + VP+ LL + G N G+V+ +GL +AI++VE R + Sbjct: 363 RATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMME 422 Query: 961 HGKGIVEAALEACRLRLRPIVMTSIAFIAGTVPLVFGHGAGAEVRSVTGITVFAGMLGVT 1020 EA ++ +V ++ A +P+ F G+ + IT+ + M Sbjct: 423 DKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSV 482 Query: 1021 LFGLFLTPVFYVALRKWVTRGEPAAPAA 1048 L L LTP L K V+ Sbjct: 483 LVALILTPALCATLLKPVSAEHHENKGG 510
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 44.0 bits (104), Expect = 8e-07 Identities = 26/172 (15%), Positives = 61/172 (35%), Gaps = 23/172 (13%) Query: 1 MTPNATPFRFPLRTVLTGAVLAVVLAGCGSKAAETGAPPPPSVSVAPVLLKEISQWDEFS 60 TP + R ++ V+A +L+ G VA + Sbjct: 50 ETPVSRRPRLVAYFIMGFLVIAFILSVLG-----------QVEIVATA-----------N 87 Query: 61 GRIEPV-ESVELRPRVSGYIDKVNYAEGTEVKKGDVLFSIDDRSYRAEFARANAALVRAR 119 G++ S E++P + + ++ EG V+KGDVL + A+ + ++L++AR Sbjct: 88 GKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQAR 147 Query: 120 TQASLARSEATRARKLSEQQAISTETWEQRRAAADQADAEVLAAQAAVDTAK 171 + + + + + + + + ++ + T + Sbjct: 148 LEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQ 199 Score = 34.8 bits (80), Expect = 6e-04 Identities = 18/102 (17%), Positives = 37/102 (36%), Gaps = 7/102 (6%) Query: 104 YRAEFARANAALVRARTQASLARSEATRARKLSEQ--QAISTETWEQRRAAADQADAEVL 161 ++ A L ++Q SE A++ + Q E ++ R Q + Sbjct: 257 QENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLR----QTTDNIG 312 Query: 162 AAQAAVDTAKLNMDWTRVRAPIDGRAGRAMV-TAGNLVTAGD 202 + + + +RAP+ + + V T G +VT + Sbjct: 313 LLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAE 354 Score = 29.4 bits (66), Expect = 0.024 Identities = 12/70 (17%), Positives = 27/70 (38%) Query: 102 RSYRAEFARANAALVRARTQASLARSEATRARKLSEQQAISTETWEQRRAAADQADAEVL 161 RAE A + R + + +S L +QAI+ ++ +A E+ Sbjct: 210 DKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELR 269 Query: 162 AAQAAVDTAK 171 ++ ++ + Sbjct: 270 VYKSQLEQIE 279
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 116 bits (291), Expect = 5e-33 Identities = 42/126 (33%), Positives = 67/126 (53%), Gaps = 11/126 (8%) Query: 117 TLNLPDGITFDFGKSALKPQFYTALNGVASTLREYN--QTMVEVVGHTDSVGSDAVNQRL 174 L + F+F K+ LKP+ AL+ + S L + V V+G+TD +GSDA NQ L Sbjct: 214 HFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGL 273 Query: 175 SEERANAVAQYLTAQGVQRERMETMGAGKRYPIADNSTDAGR---------AQNRRVEIR 225 SE RA +V YL ++G+ +++ G G+ P+ N+ D + A +RRVEI Sbjct: 274 SERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIE 333 Query: 226 LIPLRQ 231 + ++ Sbjct: 334 VKGIKD 339
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 35.1 bits (80), Expect = 7e-04 Identities = 30/121 (24%), Positives = 52/121 (42%), Gaps = 22/121 (18%) Query: 448 DTATFAARSNEGHQGLAVSGQW---RAETRAVPVGALFVPI-----AQPKARLVMAILEP 499 D + A N+G + ++G W +T V G +P ++P ++ A + Sbjct: 235 DYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINA 294 Query: 500 QAPDSLLQWGLFNLAFERKEYMEDYVAEDVAREMLARDPALKA----QFEQRLASDPAFA 555 +P+ L KE++E+Y+ D E + +D L A +E+ LA DP A Sbjct: 295 ASPNKELA----------KEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIA 344 Query: 556 A 556 A Sbjct: 345 A 345
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 33.6 bits (76), Expect = 0.003 Identities = 64/344 (18%), Positives = 107/344 (31%), Gaps = 34/344 (9%) Query: 336 FDDMVTRILRSLFAHGAFDHPTQRQPIDGKAGQRAAQ--RVAEEGSVLLRNEQATLPLSK 393 F + ++ + + A + + Q AA+ R AEE + +A + Sbjct: 193 FTEAISSLQIRMNTLTAAKASIEAAAANKAREQAAAEAKRKAEEQARQQAAIRAANTYAM 252 Query: 394 DVRRIAVIGGYADKGVMSGGGSSRVDYTINGGNAVPGLTPTTWPGPVIIHPSSPLQALRA 453 V + G++ + I+ AV G + P + + +S + R Sbjct: 253 PANGSVVATAAGRGLIQVAQGAASLAQAISDAIAVLGRVLASAPSVMAVGFASLTYSSRT 312 Query: 454 A--LPDVQIDYVDGKDRAAAARAAKAADVAIVFATQWAAESVDLPDMQLPDGQDALIEAV 511 A D D V A AA + + + A + + LP + Sbjct: 313 AEQWQDQTPDSVR------YALGMDAAKLGLPPSVNLNAVAKASGTVDLP----MRLTNE 362 Query: 512 AKANPKTTVVLETNG-------PVRMPWAEHVPAVLQAWYPGIGGGEAIANLLTGAVNPS 564 A+ N T V+ T+G PVRM + + P L +P Sbjct: 363 ARGNTTTLSVVSTDGVSVPKAVPVRMAAYNATTGLYEVTVPSTTAEAPPLILTWTPASPP 422 Query: 565 GHLPVTWPVDESQLPRPSIPGLGFKPAKPGEDTIDYAIEGANVGYKWFAARNLTPRYPFG 624 G+ + P P G P K +T I +L +P Sbjct: 423 GNQNPSSTTPVVPKPVPVYEGATLTPVKATPETYPGVITLPE---------DLIIGFPAD 473 Query: 625 HGLS--YTQFRMGGLRVEAA--NGQLTANFEVENTGQRDGAAVP 664 G+ Y FR AA GQ + + Q +GA +P Sbjct: 474 SGIKPIYVMFRDPRDVPGAATGKGQPVSGNWLGAASQGEGAPIP 517
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 117 bits (295), Expect = 1e-30 Identities = 94/400 (23%), Positives = 166/400 (41%), Gaps = 26/400 (6%) Query: 33 LAMASFMQVLDTTIANVSLPTIAGNLGASSQQATWVITSFAVSTAIALPLTGWLSRRFGE 92 L + SF VL+ + NVSLP IA + WV T+F ++ +I + G LS + G Sbjct: 19 LCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGI 78 Query: 93 TKLFVWSTLAFTIASLLCGLAQSM-GMLVVARALQGFVAGPMYPITQSLLVSIY-PREKR 150 +L ++ + S++ + S +L++AR +QG +P ++V+ Y P+E R Sbjct: 79 KRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQG-AGAAAFPALVMVVVARYIPKENR 137 Query: 151 GQALALLAMITVVAPIAGPILGGWITDNYSWEWIFLINVPLGIIASSIVGSQLRHRPEQL 210 G+A L+ I + GP +GG I W +L+ +P + + I L ++ Sbjct: 138 GKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIP---MITIITVPFLMKLLKKE 192 Query: 211 ERPR--MDYIGLILLVVGVGALQLVLDLGNDEDWFSSDKIVVLACVAAVALVVFVIWELT 268 R + D G+IL+ VG+ L F++ + V+ ++ ++FV Sbjct: 193 VRIKGHFDIKGIILMSVGIVFFML----------FTTSYSISFLIVSVLSFLIFVKHIRK 242 Query: 269 DKDPIVDLKLFRHRNFRAGTLAMVVAYAAFFSVSLLIPQWLQRDMGYTAIWAGLATAPIG 328 DP VD L ++ F G L + + ++P ++ + G G Sbjct: 243 VTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPG 302 Query: 329 ILPVLMT-PFVGKYALRFDLRMLATIAFIFMSFTSFFRSNFNLQVDFAHVATIQLVMGVG 387 + V++ G R + I F+S SF ++F L + +++ V Sbjct: 303 TMSVIIFGYIGGILVDRRGPLYVLNIGVTFLS-VSFLTASFLL--ETTSWFMTIIIVFVL 359 Query: 388 VALFFMPVL--QILLSDLDGREIAAGSGLATFLRTLGGSF 425 L F + I+ S L +E AG L F L Sbjct: 360 GGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGT 399
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 72.2 bits (177), Expect = 6e-16 Identities = 49/296 (16%), Positives = 89/296 (30%), Gaps = 42/296 (14%) Query: 82 VERGQLLVQLDPSDTAVALQQAEANLAKTVRQVRGLYRSVEGAQAELSAREVTLRSARAD 141 V R L++ S Q E NL K + A ++ E R ++ Sbjct: 184 VLRLTSLIKEQFSTWQNQKYQKELNLDKKRAER-------LTVLARINRYENLSRVEKSR 236 Query: 142 FARRKDLAASGAIS--------------NEELAHARDELAAAEAAVSGSRESFERNRALI 187 L AI+ EL + +L E+ + ++E ++ L Sbjct: 237 LDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLF 296 Query: 188 DDTEVATQ-PDVQAAAAQLRQ----AFLNHARTGVVAPVSGYVARRSAQ-VGQRVQPGTV 241 E+ + L + + APVS V + G V Sbjct: 297 -KNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAET 355 Query: 242 LMAVVPPEQ-MWVEANFKETQLKHMRLGQTVELHSDLYGGGVDYT--GRIESLGLGTGSA 298 LM +VP + + V A + + + +GQ + + + YT G + G Sbjct: 356 LMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAF----PYTRYGYLV----GK--- 404 Query: 299 FSLLPAQNASGNWIKIVQRVPVRIAIEPKQLAANPLRLGLSMKADVNLRDQQGSVL 354 + + +V V + I + L M ++ SV+ Sbjct: 405 VKNINLDAIEDQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGMRSVI 460 Score = 52.5 bits (126), Expect = 1e-09 Identities = 28/183 (15%), Positives = 64/183 (34%), Gaps = 14/183 (7%) Query: 16 PSKRRTLLRIVAILVILAVIGLVVWYFLIGRWAEDTDDAYVQG------NQVQITPMVGG 69 P RR R+VA ++ ++ + + A G +I P+ Sbjct: 52 PVSRR--PRLVAYFIMGFLVIAFILSV----LGQVEIVATANGKLTHSGRSKEIKPIENS 105 Query: 70 TVVSIGAEDGMRVERGQLLVQLDPSDTAVALQQAEANLAKTVRQVRGLYRSVEGAQAELS 129 V I ++G V +G +L++L + +++L R + Y+ + + Sbjct: 106 IVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLL-QARLEQTRYQILSRSIELNK 164 Query: 130 AREVTLRS-ARADFARRKDLAASGAISNEELAHARDELAAAEAAVSGSRESFERNRALID 188 E+ L +++ ++ E+ + +++ E + R A I+ Sbjct: 165 LPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARIN 224 Query: 189 DTE 191 E Sbjct: 225 RYE 227
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 31.0 bits (70), Expect = 0.015 Identities = 14/40 (35%), Positives = 19/40 (47%), Gaps = 7/40 (17%) Query: 15 AVRRLRPILVTTLA-------LALAACASSRGLAPQGTVL 47 RLRPIL+T+LA LA++ A S G + Sbjct: 967 VRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGV 1006
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 43.3 bits (102), Expect = 4e-08 Identities = 22/108 (20%), Positives = 43/108 (39%), Gaps = 15/108 (13%) Query: 46 HEMQEE-----TEHADALLRRILFLEGDPDMRPAEF---------SPGKTVVEMLERDLV 91 HE EE E D + R+L + G P E+ + EM++ + Sbjct: 47 HEKFEELYDHAAETVDTIAERLLAIGGQPVATVKEYTEHASITDGGNETSASEMVQALVN 106 Query: 92 VEYEVRAALAAGMKLCEDHGDYVSRDMLLKQLQDTEEDHAWWLEQQLG 139 ++ + + L E++ D + D+ + +++ E+ W L LG Sbjct: 107 DYKQISSESKFVIGLAEENQDNATADLFVGLIEEVEK-QVWMLSSYLG 153
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 67.2 bits (164), Expect = 4e-15 Identities = 30/118 (25%), Positives = 45/118 (38%) Query: 11 PRVLLVEDDPISRGFLQAVLESLPAQVDWADSLSSALDRARARRHDLWLIDVNLPDGTGS 70 +L+ +DD R L L V + ++ A DL + DV +PD Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 71 DLLRALRLLHPDVPALAHTADGNAAMQRGLQSDGFLEMLVKPLTSERLLQAVRRGLAR 128 DLL ++ PD+P L +A G + L KP L+ + R LA Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 31.7 bits (72), Expect = 0.004 Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 10/70 (14%) Query: 61 LVDTPGLHREQKRAMNRVMNRAARGSLEGVDAAVLVIEAGRWDEEDT-LAFRVLSDADVP 119 ++DTPG H + + R SL +D A+L+I A + T + F L +P Sbjct: 72 IIDTPG-HMDFLAEVYR--------SLSVLDGAILLISAKDGVQAQTRILFHALRKMGIP 122 Query: 120 VVLVVNKVDR 129 + +NK+D+ Sbjct: 123 TIFFINKIDQ 132
>PF05272#Virulence-associated E family protein Length = 892 Score = 27.3 bits (60), Expect = 0.019 Identities = 19/89 (21%), Positives = 33/89 (37%), Gaps = 4/89 (4%) Query: 33 MYQEYYAVRTSMKGLANEAGSADMDPSKLQDMFFKRLD--INSSESVKPGDVKFERIEGG 90 Q+ Y+V T+ +A+ + DP K M ++ +N + + +R G Sbjct: 786 AAQKGYSVNTTFVTIADLVQALGADPGKSSPMLEGQVRDWLNENGWEYLRETSGQRRRGY 845 Query: 91 WRMKVNYEVRRELV--GNLDVVGKFDTEQ 117 R +V V E G D +Q Sbjct: 846 MRPQVWPPVIAEDKEADQAHAPGDQDQQQ 874
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 144 bits (366), Expect = 7e-39 Identities = 95/455 (20%), Positives = 179/455 (39%), Gaps = 85/455 (18%) Query: 3 NIRNFSIIAHVDHGKSTLADRIIQLCGG---LQAREMEAQVLDSNPIERERGITIKAQSV 59 I N ++AHVD GK+TL + ++ G L + + D+ +ER+RGITI+ Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 60 SLPYTAKDGQTYFLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAAQGVEAQSVANCYTA 119 S + +N IDTPGH+DF EV RSL+ +GA+L++ A GV+AQ+ + Sbjct: 62 SFQWENTK-----VNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHAL 116 Query: 120 VEQGLEVVPVLNK-----IDLP----------TADIERAKA----------------EIE 148 + G+ + +NK IDL +A+I + + + Sbjct: 117 RKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWD 176 Query: 149 AVIG--------------IDAEDAVAV----------------SAKTGLNIDLVLEAIVH 178 VI ++A + SAK + ID ++E I + Sbjct: 177 TVIEGNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITN 236 Query: 179 RIPPPKPRDTDKLQALIIDSWFDNYLGVVSLVRVMQGEIKPGSKIQVMSTGRTHLVDKVG 238 + R +L + + ++ +R+ G + +++ + + + Sbjct: 237 KFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKIKITEMYT 296 Query: 239 VFTPKRKELVALGAGEVGWINASIKDVHGAPVGDTLTLAADPAPHALPGFQEMQPRVFAG 298 + ++ +GE+ + + + +GDT L + P + Sbjct: 297 SINGELCKIDKAYSGEIVILQNEFLKL-NSVLGDTKLLPQRERI------ENPLPLLQTT 349 Query: 299 LFPVDAEDYPDLREALDKLRLNDAALRFE--PESSEAMGFGFRCGFLGMLHMEIVQERLE 356 + P + L +AL ++ +D LR+ + E + FLG + ME+ L+ Sbjct: 350 VEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEII-----LSFLGKVQMEVTCALLQ 404 Query: 357 REYNLNLISTAPTVVY--EVLKTDGTIIPMDNPSK 389 +Y++ + PTV+Y LK I ++ P Sbjct: 405 EKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPN 439
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 72.0 bits (176), Expect = 8e-16 Identities = 33/163 (20%), Positives = 58/163 (35%), Gaps = 28/163 (17%) Query: 133 AGKSMGSGFIISADGYVLTNHHVVDGASEVTVKLTDRR-----------EFKA-KVVGSD 180 G + SG ++ +LTN HVVD L F A ++ Sbjct: 99 TGTFIASGVVV-GKDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYS 157 Query: 181 EQFDVALLKIEA--------KGLPTVRIGDSNTLKPGQWVVAIGSPFGLDHSVTAGIVSA 232 + D+A++K + + + ++ + Q + G P V+ Sbjct: 158 GEGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKP-------VAT 210 Query: 233 TGRSNPYADQRYVPFIQTDVAINQGNSGGPLLNTRGEVVGINS 275 S +Q D++ GNSG P+ N + EV+GI+ Sbjct: 211 MWESKGKITYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHW 253
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 29.6 bits (66), Expect = 0.016 Identities = 29/208 (13%), Positives = 49/208 (23%), Gaps = 15/208 (7%) Query: 74 TAKVRAAVAEEPAPAAAPAARPAARWRWGGGAALAASVAAIALFVSRERLPEVAAPAPAE 133 T + A E A+ A VA + E A E Sbjct: 1050 TVEKNEQDATETTAQNREVAKEAKSNV--KANTQTNEVAQSGSETKETQTTETKETATVE 1107 Query: 134 -----QVFATTAQLPASTPAPQAPKAPDAPDDVVALAAAVPAAALASARRGAATRNQQVA 188 +V Q + +PK + A + + + N Sbjct: 1108 KEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTAD 1167 Query: 189 RSVAARNQQAPARMVASAAAPAATPAVASPAAANPFTHPEATLQARPWPRAALAGSGESP 248 + PA+ +S T + + +PE T A P S + Sbjct: 1168 -------TEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPK 1220 Query: 249 LNASFS-QSRQAPAFYPFEPAPQAAAAA 275 S +S + + A Sbjct: 1221 NRHRRSVRSVPHNVEPATTSSNDRSTVA 1248
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 69.5 bits (170), Expect = 3e-17 Identities = 27/114 (23%), Positives = 54/114 (47%), Gaps = 5/114 (4%) Query: 6 RLLMVEDQQELRDLIGEALRDAGITVDTADDGHCALRMLRENGPYDVVFSDIRMPNGMSG 65 +L+ +D +R ++ +AL AG V + R + G D+V +D+ MP + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAA-GDGDLVVTDVVMP-DENA 62 Query: 66 IELSEQVSQLLPQARIILASGFAKAQLPPLPAQ---VDFLPKPYRLRQLIGLLK 116 +L ++ + P +++ S ++ D+LPKP+ L +LIG++ Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>PF06580#Sensor histidine kinase Length = 349 Score = 33.3 bits (76), Expect = 0.002 Identities = 45/256 (17%), Positives = 84/256 (32%), Gaps = 63/256 (24%) Query: 132 ERHEAQQLLQHAQQALLQSQKVEALGRLTLGLAHDFNNLLTVMVTSLDLIALRAGEDART 191 ++ + + Q AQ L++Q + H N +L+ I ED Sbjct: 150 DQWKMASMAQEAQLMALKAQ-INP---------HFMFN-------ALNNIRALILEDP-- 190 Query: 192 RMLVEAAQTAVDRGTLLTRQLLAFARGQR--LVPERHAPAAVVERSLELLRRACPAGISL 249 A+ + + L R L ++ ++ L E VV+ L+L + Sbjct: 191 ----TKAREMLTSLSELMRYSLRYSNARQVSLADE----LTVVDSYLQLASIQFEDRLQF 242 Query: 250 RVDFADALPDVRVDPGQLEAALLNLVFNSCDAMPAGGSIVLSASTQQRAPLDDPHGSARA 309 A+ DV+V P ++ + N + + +P GG I+L + Sbjct: 243 ENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDN------------G 290 Query: 310 YVGIAVSDTGPGMSAQVAQRASEPFFTTKEVGKGSGLGLSQVHG-----FAAQSGGFVDL 364 V + V +TG K + +G GL V + ++ + L Sbjct: 291 TVTLEVENTGSLA--------------LKNTKESTGTGLQNVRERLQMLYGTEAQ--IKL 334 Query: 365 QTAPGRGTTVTLLLPA 380 G +L+P Sbjct: 335 SEKQG-KVNAMVLIPG 349
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 85.7 bits (212), Expect = 2e-19 Identities = 32/118 (27%), Positives = 60/118 (50%), Gaps = 2/118 (1%) Query: 923 LDGATVLLAEDDVRNIFALSSVLEPLGVTLQIARNGREALEHLAKHEVDLVLMDIMMPEM 982 + GAT+L+A+DD L+ L G ++I N +A + DLV+ D++MP+ Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 983 DGITAMRQIRANRQWQDLPIIALTAKAMADDREHCLQAGANDYIAKPIDVDKLVSLCR 1040 + + +I+ DLP++ ++A+ + GA DY+ KP D+ +L+ + Sbjct: 61 NAFDLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116 Score = 67.5 bits (165), Expect = 1e-13 Identities = 37/151 (24%), Positives = 58/151 (38%), Gaps = 15/151 (9%) Query: 660 ILAVEDETRFAQALVDLAHELDFDCVVAPNAEEALRLAAELRPSGILLDIGLPDASGLSV 719 IL +D+ L +D + NA R A ++ D+ +PD + + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 720 LERLK-RNPATRHIPVHVVSA---LERSQIALELGAVGYLIKPATRELLAGAIRQLEETN 775 L R+K P +PV V+SA + A E GA YL KP L G I + Sbjct: 66 LPRIKKARP---DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 776 ARALRRLL--------IVEDDSALRANLELL 798 R +L +V +A++ +L Sbjct: 123 KRRPSKLEDDSQDGMPLVGRSAAMQEIYRVL 153 Score = 65.2 bits (159), Expect = 6e-13 Identities = 28/143 (19%), Positives = 59/143 (41%), Gaps = 7/143 (4%) Query: 781 RLLIVEDDSALRANLELLLARDQLEIVAVGTIAEAMDQLGSATFDCMVTDLALPDGSGYD 840 +L+ +DD+A+R L L+R ++ A + + D +VTD+ +PD + +D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 841 LLERMAGNDAVAFPPVIVYTGRALTRDEEQRLRRYSKSIIIKGVRSPERLLDEVTLFLHS 900 LL R+ A PV+V + + + + + + K L E+ + Sbjct: 65 LLPRI--KKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFD-----LTELIGIIGR 117 Query: 901 VEASLPSDQQRLLREARRRDAVL 923 A +L +++ ++ Sbjct: 118 ALAEPKRRPSKLEDDSQDGMPLV 140
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 79.1 bits (195), Expect = 3e-18 Identities = 33/151 (21%), Positives = 59/151 (39%), Gaps = 12/151 (7%) Query: 16 AKILIVDDVPQNLVAMEALLQREGIQVLCAASGAQALELLLEHDVALALLDVHMPEMDGF 75 A IL+ DD + L R G V ++ A + D L + DV MP+ + F Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 76 SLAELMRGSQRSRHVPIIFLTASPNDPMRAFQGYETGAVDFLHKPIEPHVILSKVNVFIE 135 L ++ + +P++ ++A N M A + E GA D+L KP + ++ Sbjct: 64 DLLPRIK--KARPDLPVLVMSAQ-NTFMTAIKASEKGAYDYLPKPFDLTELIG------- 113 Query: 136 LYQQRRLLKARNASLERALTLNETMMAVLTH 166 R L + ++ M ++ Sbjct: 114 --IIGRALAEPKRRPSKLEDDSQDGMPLVGR 142
>PF07201#Hypersensitivity response secretion protein HrpJ Length = 293 Score = 27.5 bits (61), Expect = 0.043 Identities = 9/36 (25%), Positives = 13/36 (36%), Gaps = 7/36 (19%) Query: 13 RGGPVDVEALRGLYRDGVI-------ALDSLVWREG 41 + G ++ LR YRD V+ L R Sbjct: 189 QSGVNPLQPLRDTYRDAVMGYQGIYAIWSDLQKRFP 224
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 29.6 bits (66), Expect = 0.017 Identities = 21/103 (20%), Positives = 30/103 (29%), Gaps = 1/103 (0%) Query: 60 PAATPETASVFTPAPITADPSPGAATSAEQVPEAGFTPVTPQ-TTQPDSVSAAHISTPVD 118 PA +V P +P P E EA P+ +P + P Sbjct: 57 PADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKR 116 Query: 119 AGSVASSAPSPGAWSARTAAEPSEHQPATTASPATPAQATPLP 161 S P+ + A S A T+ P T + P Sbjct: 117 DVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRA 159
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 57.9 bits (140), Expect = 9e-12 Identities = 31/115 (26%), Positives = 46/115 (40%), Gaps = 12/115 (10%) Query: 140 GATVLYIEDSRVVAEATKRMLERQSLKVVHVLTAEDAFALLTAESLGRTERRIDVVLTDV 199 GAT+L +D + + L R V A + + A D+V+TDV Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGD-------GDLVVTDV 55 Query: 200 TLKGELNGRDVVERIRIDFAYGKRRLPVLVMTGDTNPRNQSELLRAGANDLVQKP 254 + E N D++ RI+ LPVLVM+ + GA D + KP Sbjct: 56 VMPDE-NAFDLLPRIKKARP----DLPVLVMSAQNTFMTAIKASEKGAYDYLPKP 105 Score = 52.1 bits (125), Expect = 8e-10 Identities = 21/88 (23%), Positives = 39/88 (44%), Gaps = 4/88 (4%) Query: 12 DAPRVMVVDGSKLVRKLIADVLKRDLPNVQVIGCASIAEARDALEAGAVDLVTTSLSLPD 71 ++V D +R ++ L R V ++ A + AG DLV T + +PD Sbjct: 2 TGATILVADDDAAIRTVLNQALSRA--GYDVRITSNAATLWRWIAAGDGDLVVTDVVMPD 59 Query: 72 GDGLTLARSVREAAGQAYVPVIVVSGDA 99 + L +++A + +PV+V+S Sbjct: 60 ENAFDLLPRIKKA--RPDLPVLVMSAQN 85
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 32.0 bits (72), Expect = 0.008 Identities = 33/181 (18%), Positives = 54/181 (29%), Gaps = 24/181 (13%) Query: 378 QKIPVEPVTTELLTPLPRTPRATVE--GEEVDDDAGDSVGTIFREAREQRAADEARRGGG 435 + PV P P P TP T E E ++ E EQ A + + Sbjct: 1021 DEAPVPP-------PAPATPSETTETVAENSKQESKTV------EKNEQDATETTAQNRE 1067 Query: 436 RSGPGGASRSGSGGGRRDGAGADGKPRPPRRKPRVEGEADPAAAPSETPVVVAAAAETPA 495 + ++S + A + E + V E P Sbjct: 1068 VAK---EAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPK 1124 Query: 496 VTAAEGERAPRKRRRRRNGRPVEGAEPVVASTPVPAPAAPRKPTQVVAKPVRAAAKPSGS 555 VT+ + K+ + +P AEP + P P+ T A + A + S + Sbjct: 1125 VTS----QVSPKQEQSETVQP--QAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSN 1178 Query: 556 P 556 Sbjct: 1179 V 1179
>cdtoxina#Cytolethal distending toxin A signature. Length = 258 Score = 29.7 bits (66), Expect = 0.031 Identities = 15/43 (34%), Positives = 18/43 (41%), Gaps = 2/43 (4%) Query: 17 GSQQPNLPLPSSPAPEAPRPAQTPSPAAESAPAQS-SGDGGAA 58 +P LPLP P P P P P +APA S G+ Sbjct: 48 SPDEPGLPLPG-PGPALPTNGAIPIPEPGTAPAVSLMNMDGSV 89
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 36.5 bits (84), Expect = 7e-05 Identities = 23/131 (17%), Positives = 36/131 (27%), Gaps = 24/131 (18%) Query: 100 AKPGEKNQYLVSIRSAHFGGEASDGSSVRAKDMTP-----PSYPKAAFQDGATGIVYLLL 154 +N S+ S + A P YP A G V + Sbjct: 125 PASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKF 184 Query: 155 KIGRDGKVADLVAEQVNLTVSIPAAKRERVRKTLADASIAKARTWTFDPPSDGPEHTAPY 214 + DG+V + V + + PA R W ++P G Sbjct: 185 DVTPDGRV-----DNVQILSAKPA-------NMFEREVKNAMRRWRYEPGKPGSG----- 227 Query: 215 WTMRVPVSFDI 225 + V + F I Sbjct: 228 --IVVNILFKI 236
>PF09025#YopR Core Length = 143 Score = 27.7 bits (61), Expect = 0.036 Identities = 18/68 (26%), Positives = 26/68 (38%), Gaps = 12/68 (17%) Query: 38 QVRSLEQRLG--YPLLQRHARGVSATLQGQQLLDRIAPHLDAIA----------EAFQPF 85 QV + EQ LG P R G+ G++LL R A L + A P Sbjct: 28 QVLAFEQALGGEPPAAGRRLAGLENGALGERLLQRFAQPLQGLEADRLELKAMLRAELPL 87 Query: 86 AARREDTL 93 +++ L Sbjct: 88 GRQQQTFL 95
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 29.0 bits (64), Expect = 0.038 Identities = 18/61 (29%), Positives = 29/61 (47%), Gaps = 4/61 (6%) Query: 13 ALPTLAAAQAAPRPEVQAA--AAPLQAKVVQWRRDFHQHPELSNREERTAATVAAQLRKL 70 A P + Q P P V A +APL + +W++ QH L R+ + +A + + L Sbjct: 211 ASPLITPHQTQPLPTVAAPVLSAPLGSH--EWQQSLSQHISLFTRQGQQSAELRLHPQDL 268 Query: 71 G 71 G Sbjct: 269 G 269
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 30.7 bits (69), Expect = 0.023 Identities = 25/100 (25%), Positives = 40/100 (40%), Gaps = 6/100 (6%) Query: 306 IANIVSKDVAEVAKGYERVIRPRFADAKFFFDEDLKQGLEAMGAGLASVTYQAKLGTVAD 365 IA I D + +G +VI ++A A DL + L + + + S AK D Sbjct: 253 IAMIKQLDRQQATQGNTKVIYLKYAKAS-----DLVEVLTGISSTMQSEKQAAKPVAALD 307 Query: 366 KVARVAALAEAIAPQVGADPVQARRAAEL-AKNDLQSRMV 404 K + A + A V A P + A+ D++ V Sbjct: 308 KNIIIKAHGQTNALIVTAAPDVMNDLERVIAQLDIRRPQV 347
>PF04335#VirB8 type IV secretion protein Length = 227 Score = 31.3 bits (71), Expect = 0.003 Identities = 14/70 (20%), Positives = 28/70 (40%), Gaps = 11/70 (15%) Query: 168 LLWLLLMVATFAAL--TLALFVM-------PPQVMFDRSTGGHALRESLRASLHNLP--A 216 L W++ VA A +A+ + P + DR+TG ++ L A Sbjct: 34 LAWVVAGVAGALATAGVVAVAALTPLKTVEPYVITVDRNTGEASIAAKLHGDATITYDEA 93 Query: 217 MLVFFVLAFI 226 + +F+ ++ Sbjct: 94 VRKYFLATYV 103
>TATBPROTEIN#Bacterial sec-independent translocation TatB protein signature. Length = 171 Score = 86.2 bits (213), Expect = 1e-23 Identities = 37/89 (41%), Positives = 56/89 (62%), Gaps = 1/89 (1%) Query: 1 MFDIGFSELALIAVVALVVLGPERLPKAARFAGLWVRRARMQWDSVKQELERELEAEELK 60 MFDIGFSEL L+ ++ LVVLGP+RLP A + W+R R +V+ EL +EL+ +E + Sbjct: 1 MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNELTQELKLQEFQ 60 Query: 61 RSLQDVQ-ASLREAEGQLRNTQQQVEDGA 88 SL+ V+ ASL +L+ + ++ A Sbjct: 61 DSLKKVEKASLTNLTPELKASMDELRQAA 89
>TATBPROTEIN#Bacterial sec-independent translocation TatB protein signature. Length = 171 Score = 29.6 bits (66), Expect = 7e-04 Identities = 10/41 (24%), Positives = 18/41 (43%) Query: 1 MGSFSIWHWLIVLVIVLLVFGTKRLTSGAKDLGSAVKEFKK 41 M L+V +I L+V G +RL K + ++ + Sbjct: 1 MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRS 41
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 29.3 bits (65), Expect = 0.021 Identities = 17/54 (31%), Positives = 24/54 (44%), Gaps = 2/54 (3%) Query: 236 GDTPPPAPRPVSQ-SPAQAPATPPPPSNEASTMPIQPSATPPQQQGFQPVSDGE 288 G P +P+ + SPA+ PA P P+ T P P P P +DG+ Sbjct: 318 GSAEAPNAQPLPEVSPAENPANNPAPNENPGTRP-NPEPDPDLNPDANPDTDGQ 370