>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 28.8 bits (64), Expect = 0.026 Identities = 24/156 (15%), Positives = 51/156 (32%), Gaps = 9/156 (5%) Query: 3 TSRDVARAAGVSQATV-----SRALNRPETVSQKTRERVQAAVQTLGYHPHSGAIAMKTQ 57 + ++A+AAGV++ + ++ E + ++ P ++ Sbjct: 33 SLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPGDPLSVLREI 92 Query: 58 RTKTIGVVVSELSNPFFQEIFETLSQEFAKAGSRVIVWDSALHE--RDAIRALQERSVDG 115 + V+E EI EF + V L D I + ++ Sbjct: 93 LIHVLESTVTEERRRLLMEIIFH-KCEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEA 151 Query: 116 VIMSAWDEDAQEMRDILETGLPVVLLNRTAPKGSFD 151 ++ A D + I+ + ++ N SFD Sbjct: 152 KMLPA-DLMTRRAAIIMRGYISGLMENWLFAPQSFD 186
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 83.7 bits (207), Expect = 1e-20 Identities = 32/128 (25%), Positives = 59/128 (46%), Gaps = 1/128 (0%) Query: 13 GRVLVVDDEQPLAQMVASYLIRAGFDTRQAHTGTQAVDEARRFSPDVVVLDLGLPELDGL 72 +LV DD+ + ++ L RAG+D R D+VV D+ +P+ + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 73 EVCRRIRT-FSDCYILMLTARGSEDDKISGLTLGADDYITKPFSVRELVTRVHAVLRRPR 131 ++ RI+ D +L+++A+ + I GA DY+ KPF + EL+ + L P+ Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 132 TSTTPPQV 139 + + Sbjct: 124 RRPSKLED 131
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 31.1 bits (70), Expect = 0.007 Identities = 21/77 (27%), Positives = 24/77 (31%), Gaps = 15/77 (19%) Query: 66 LITLAVALPTALISALLASLWLSRRLRTPL------QDLTRAATSLTAGN--YR------ 111 I L VA A+ + LW L QD LT N YR Sbjct: 24 RIPLIVAGSAAVAIVVAMVLWAKTPDYRTLFSNLSDQDGGAIVAQLTQMNIPYRFANGSG 83 Query: 112 -IRVPAGEAGPEVTTLA 127 I VPA + LA Sbjct: 84 AIEVPADKVHELRLRLA 100
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 25.2 bits (55), Expect = 0.033 Identities = 7/48 (14%), Positives = 22/48 (45%), Gaps = 5/48 (10%) Query: 26 IENKLNGLDGVENAEVKFSSGRILITHDPQK-----VSVRDLVTAVAE 68 +++ L+ L+GV + ++ + + I D ++ D++ + Sbjct: 162 VKDTLSRLNGVGDVQLFGAQYAMRIWLDADLLNKYKLTPVDVINQLKV 209
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.8 bits (67), Expect = 0.016 Identities = 19/111 (17%), Positives = 39/111 (35%), Gaps = 11/111 (9%) Query: 30 TTQDLALRSRIVLECATGASNSEVARRLGISLPTVGKWRARFIDKRLDGLVDEPRPGRPA 89 T + + R + + + + L IS R F D P Sbjct: 375 TREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYF-----ASFGDALPPSGLY 429 Query: 90 TIGIDRVE-QVIIDTLESTPANATHWSRASMAEKSGLSKSTVGRIWKAFGL 139 + +E +I+ L AT ++ A+ GL+++T+ + + G+ Sbjct: 430 DRVLAEMEYPLILAALT-----ATRGNQIKAADLLGLNRNTLRKKIRELGV 475
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 26.9 bits (59), Expect = 0.021 Identities = 21/97 (21%), Positives = 33/97 (34%), Gaps = 8/97 (8%) Query: 11 MNRLGRAMADPTRSRIL---LSLLEAPGYPA----QLARELELTRPNVSNHLACLRDCGI 63 M R + A TR IL L L G + ++A+ +TR + H D Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 64 IVAEPEGRQTRYEIVDAHLAQALNALLDVTLAVDEHA 100 + E E+ + A+ L V + H Sbjct: 61 EIWELSESNIG-ELELEYQAKFPGDPLSVLREILIHV 96
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 27.7 bits (61), Expect = 0.032 Identities = 7/24 (29%), Positives = 13/24 (54%) Query: 166 EGYSMSKIVEKTGITRSSLYRHLP 189 S+ +I + G+TR ++Y H Sbjct: 30 SSTSLGEIAKAAGVTRGAIYWHFK 53
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 26.0 bits (57), Expect = 0.047 Identities = 17/60 (28%), Positives = 27/60 (45%), Gaps = 1/60 (1%) Query: 62 TIAVFIIAVGMIIAAGAAVRWMNVERAMRKQKPLPVPAIIPFLSIAALVASAAVLVLIIV 121 T+ ++A+G+++ A V NVER M + K P A +S +VL V Sbjct: 394 TMFGMVLAIGLLVD-DAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAV 452
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 36.0 bits (83), Expect = 2e-04 Identities = 25/122 (20%), Positives = 42/122 (34%), Gaps = 14/122 (11%) Query: 286 FGSFGDRHGWARTVFWSGSIGGAVTLALVYFIPMFGVQAGMSNGVVFGITIAAGALFGVS 345 +G D+ G R + + I FG G F + I A + G Sbjct: 69 YGKLSDQLGIKRLLLFGIIINC------------FGSVIGFVGHSFFSLLIMARFIQGAG 116 Query: 346 LAGFVPLSAIAVS--LDPKHPGAAMATYNLGVGGAVAVGPLLVAVFHPLIGPTGLILVMI 403 A F L + V+ + ++ G A V VGP + + I + L+L+ + Sbjct: 117 AAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPM 176 Query: 404 AL 405 Sbjct: 177 IT 178 Score = 30.2 bits (68), Expect = 0.018 Identities = 29/184 (15%), Positives = 72/184 (39%), Gaps = 6/184 (3%) Query: 25 LTIFMIGDGVETNILEPFLSSEHGFSVSLAGTLVTVYGVAVAIAAFFAAALSDLWGPRKV 84 L+ F + + + N+ P ++++ + + T + + +I LSD G +++ Sbjct: 22 LSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRL 81 Query: 85 MILGASIWIVFELIFLTVALTTDHTWLIFLAYGLRGFGYPFFAYGFLVWITATASPKQLG 144 ++ G I +I + L+ +A ++G G F +V + + G Sbjct: 82 LLFGIIINCFGSVI---GFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRG 138 Query: 145 TGVGWFYVAFSAGLPTLGALVATISMQYVNLTFYETLWVSLVLVVIGSLIALLGVKERRG 204 G + A +G + + Y++ ++ L + ++ ++ + L KE R Sbjct: 139 KAFG-LIGSIVAMGEGVGPAIGGMIAHYIHWSYL--LLIPMITIITVPFLMKLLKKEVRI 195 Query: 205 RHPL 208 + Sbjct: 196 KGHF 199
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 28.9 bits (64), Expect = 0.043 Identities = 15/45 (33%), Positives = 28/45 (62%), Gaps = 2/45 (4%) Query: 311 GVTLQPYLEGERTPNRPAARGVLAGLNSATTREDFARATVEGLLL 355 GVT+ P +G+ P++P + AG+N+A+ ++ A+ +E LL Sbjct: 269 GVTVLPTFKGQ--PSKPFVGVLSAGINAASPNKELAKEFLENYLL 311
>CLENTEROTOXN#Clostridium enterotoxin signature. Length = 319 Score = 32.3 bits (73), Expect = 0.003 Identities = 14/47 (29%), Positives = 18/47 (38%), Gaps = 8/47 (17%) Query: 211 VRSAEPYERILSPVPAD--------LISNPADVLGTLLFTGTYPVTT 249 V S + + IL A L SNPA L + +YP T Sbjct: 190 VPSTDIEKEILDLAAATERLNLTDALNSNPAGNLYDWRSSNSYPWTQ 236
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 50.8 bits (121), Expect = 4e-10 Identities = 26/204 (12%), Positives = 62/204 (30%), Gaps = 18/204 (8%) Query: 8 RLGRPRNENLDSKILQATRNIIEKD--ERVSIEAIVQESGASRASVYRRWPSLNNLIANA 65 R + + IL + + S+ I + +G +R ++Y + ++L + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 66 LDEG--RKSEVLIDLSGTVKDGFIAMFFGDLSVAHGEDYTMERFRKRMELAMSDPKVQQV 123 + E+ ++ +++ L T ER R+ + + Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEER-RRLLMEIIFHKCEFVG 121 Query: 124 YWSSYVEKRRKYPLQALQLAKD-------RGEIREDVDIDAALDSIYGA---LYYQFLIR 173 + + +R L++ + + D+ A + G L +L Sbjct: 122 EMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFA 181 Query: 174 GQDITSKDCRGRARAAFELIWRGM 197 Q K AR ++ Sbjct: 182 PQSFDLKK---EARDYVAILLEMY 202
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 33.3 bits (76), Expect = 0.002 Identities = 24/102 (23%), Positives = 42/102 (41%), Gaps = 11/102 (10%) Query: 112 RIVDVTPGRVREALDEGKICIVAGFQGV-----NKETRDVTTLGRGGSDTTAVALAAALN 166 V+ +++ ++ G I I +G GV + E + V + D LA +N Sbjct: 172 GHVEAET--IKKLVERGVIVIASGGGGVPVILEDGEIKGVEAVI--DKDLAGEKLAEEVN 227 Query: 167 ADVCEIYSDVDGVYTADPRIVPNAQKLEKLSFEEMLELAAVG 208 AD+ I +DV+G Q L ++ EE+ + G Sbjct: 228 ADIFMILTDVNGAALYYGT--EKEQWLREVKVEELRKYYEEG 267
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 25.7 bits (56), Expect = 0.029 Identities = 13/61 (21%), Positives = 26/61 (42%), Gaps = 6/61 (9%) Query: 15 GEPVRLRILSH----LAAEGCTPTTVNELTEIMGLSQPTISHHLKKMTDAGLLARIPEGR 70 + R IL + +G + T++ E+ + G+++ I H K + L + I E Sbjct: 9 AQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFK--DKSDLFSEIWELS 66 Query: 71 T 71 Sbjct: 67 E 67
>OMADHESIN#Yersinia outer membrane adhesin signature. Length = 455 Score = 27.9 bits (61), Expect = 0.038 Identities = 21/64 (32%), Positives = 30/64 (46%) Query: 116 VLVVPKDHRLSHHDAVELKEVEGEHFVAMTNKYTTRDLADQLCAEAGISPTISVESDSSY 175 VL + K H S E + VA T T + A++ AEA S + +S SS+ Sbjct: 277 VLNMAKAHSNSVARTTLETAEEHANSVARTTLETAEEHANKKSAEALASANVYADSKSSH 336 Query: 176 TLRT 179 TL+T Sbjct: 337 TLKT 340
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 93.4 bits (232), Expect = 3e-24 Identities = 41/136 (30%), Positives = 73/136 (53%) Query: 2 SKILLAEDDAGIADFIVRGLIREGFECEITESGAEAFARAHSGDFDLMVLDLGLPHMDGT 61 + IL+A+DDA I + + L R G++ IT + A + +GD DL+V D+ +P + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 DILEQLRNLQVTLPIIVLTARTNIEDRLRTLEGGADDYMPKPFQFAELLARIKLRLAKHT 121 D+L +++ + LP++V++A+ ++ E GA DY+PKPF EL+ I LA+ Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 122 AQESPTDARVLRNGDV 137 + S + + Sbjct: 124 RRPSKLEDDSQDGMPL 139
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 60.0 bits (145), Expect = 4e-12 Identities = 36/190 (18%), Positives = 63/190 (33%), Gaps = 48/190 (25%) Query: 220 GSGFVASPDYVVTNAHVVAGTSTVSLDTMI-------------GTRSAEVVFYDPNLDIA 266 SG V D ++TN HVV T G + ++ Y D+A Sbjct: 104 ASGVVVGKDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEGDLA 163 Query: 267 VL-YSPDL-------GLDPLPWA-STPLDTGDEAIVMGFPQSGPFNASPARVRERIMITG 317 ++ +SP+ + P + + V G+P Sbjct: 164 IVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYP------------------GD 205 Query: 318 SNIYANGQHEREAYSVRGS-------IQSGNSGGPMANEMGEVVGVVFGAAIDGSDTGYV 370 + + + + ++G GNSG P+ NE EV+G+ +G + G V Sbjct: 206 KPVATMWESKGKITYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHWG-GVPNEFNGAV 264 Query: 371 LTAEEVQERI 380 E V+ + Sbjct: 265 FINENVRNFL 274
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 37.1 bits (86), Expect = 6e-05 Identities = 26/114 (22%), Positives = 41/114 (35%), Gaps = 11/114 (9%) Query: 64 AEAGSPTKPLVLLIHGAFGGWYDY-REVIGPLADAGFHVAAIDLRGYGMSDKPPTGYDLR 122 A + PLV+ + G GGW + V G L G+ V Y K P + Sbjct: 44 AASSHTKPPLVIFLSGD-GGWATLDKAVGGILQQQGWPVVGWSSLKYYWKQKDP-----K 97 Query: 123 HAAGELSSVI----AALGHDDAFLVGSDTGASIAWAIASMYPERVRGLISLGAI 172 + ++I A G L+G GA + + + P R R + + Sbjct: 98 DVTQDTLAIIDKYQAEFGTQKVILIGYSFGAEVIPFVLNEMPARYRKNVLGAVL 151
>SECGEXPORT#Protein-export SecG membrane protein signature. Length = 110 Score = 26.8 bits (59), Expect = 0.019 Identities = 14/37 (37%), Positives = 22/37 (59%), Gaps = 2/37 (5%) Query: 8 IAALAIAGTLILP--ATAHAQSNFSAGSSSFDFGSSG 42 I A+ + G ++L A ++F AG+S+ FGSSG Sbjct: 11 IVAIGLVGLIMLQQGKGADMGASFGAGASATLFGSSG 47
>PERTACTIN#Pertactin signature. Length = 922 Score = 30.5 bits (68), Expect = 0.004 Identities = 19/54 (35%), Positives = 22/54 (40%) Query: 82 GLIAGGVHWAVQQRMIPNPLPGIIPNPPALAPQAPAPAPAPAPAPQAVAPQAVA 135 L+ A + P P PG P P PQ P P P P+A APQ A Sbjct: 561 SLVGAKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPPA 614 Score = 28.5 bits (63), Expect = 0.020 Identities = 21/58 (36%), Positives = 23/58 (39%), Gaps = 2/58 (3%) Query: 86 GGVHWAVQQRMIPNPLPGIIPNP-PALAPQAPAPAPAPAPAPQAVAPQAVAPAPAPAP 142 G W++ P P P P P P PQ P P P P PQ APAP P Sbjct: 556 GNGQWSLVGAKAP-PAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQP 612 Score = 27.8 bits (61), Expect = 0.034 Identities = 19/54 (35%), Positives = 21/54 (38%) Query: 110 ALAPQAPAPAPAPAPAPQAVAPQAVAPAPAPAPVQTNRTYKNCTEVWNVLGRSI 163 A AP AP PAP P P P PQ P P P Q + GR + Sbjct: 565 AKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPPAGREL 618
>adhesinb#Adhesin B signature. Length = 310 Score = 31.4 bits (71), Expect = 0.019 Identities = 17/52 (32%), Positives = 29/52 (55%), Gaps = 5/52 (9%) Query: 167 VLAITEQVADELVSRGVPREKIHV---VPNAVDPHEFMPLPADLEYAVSKKL 215 V+A +AD +++ + +KI++ VP DPHE+ PLP D++ L Sbjct: 36 VVATNSIIAD--ITKNIAGDKINLHSIVPVGQDPHEYEPLPEDVKKTSQADL 85
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 71.9 bits (176), Expect = 1e-16 Identities = 57/275 (20%), Positives = 107/275 (38%), Gaps = 28/275 (10%) Query: 4 YAVAALALLTLAGCST---SEEVAVSSDSAPQRIVIAQANFLDLALALDLEPVGTTYWGG 60 ++ LLT S A ++ P RIV + ++L LAL + P G Sbjct: 5 PLISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGIVPYGVA---- 60 Query: 61 AGGVQDYLL----DSVPASMEVVGNDDEPNFETVAKLQPDLIIGDEEIETNLAKYEAIAP 116 +Y L +P S+ VG EPN E + +++P ++ + IAP Sbjct: 61 --DTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAP 118 Query: 117 VSIIKSVDDNGSNSW---RDQLTALAELTGTQEKAAAVIEEADKSVASLDSKITSPGEKT 173 D G R LT +A+L Q A + + + + S+ + G + Sbjct: 119 GRGFNFSD--GKQPLAMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARP 176 Query: 174 MLLR--IREEQVRQYFPDSFVGAGVPQRLQNITLVESAVPSENGQW--SVIPPENIGLLD 229 +LL I + + P+S Q + + + +A E W + + + + Sbjct: 177 LLLTTLIDPRHMLVFGPNSLF-----QEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYK 231 Query: 230 ADRIIAF-IDSPQALENAESNPLWRQLPAVKNGQL 263 ++ F D+ + ++ + PLW+ +P V+ G+ Sbjct: 232 DVDVLCFDHDNSKDMDALMATPLWQAMPFVRAGRF 266
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 54.2 bits (130), Expect = 3e-11 Identities = 32/181 (17%), Positives = 71/181 (39%), Gaps = 15/181 (8%) Query: 7 PSLRETKRQKTLEAIEDNATRLILERGFDNVTVEDICAEAGISKRTFFNYVESKESV--A 64 + + Q+T + I D A RL ++G + ++ +I AG+++ + + + K + Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 65 IGHTAKLPTDEEREGFLATRHENIIDTVFDLVINLFGNHDNSKSGVAGDIMRRRKEIRVK 124 I ++ E + A + + + +++I++ +S V + R EI + Sbjct: 62 IWELSESNIGELELEYQAKFPGDPLSVLREILIHVL------ESTVTEERRRLLMEI-IF 114 Query: 125 HPELAVQHFARFHQAREGLEH----LIVEYFEKWPGSQHLDEPADREAIA--IVGLLISV 178 H V A QA+ L I + + ++ L A + G + + Sbjct: 115 HKCEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGL 174 Query: 179 M 179 M Sbjct: 175 M 175
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 143 bits (363), Expect = 1e-39 Identities = 110/425 (25%), Positives = 189/425 (44%), Gaps = 20/425 (4%) Query: 42 KTTGRVGFIIAALMLAMLLSSLGQTIFGSALPTIVGELGGV-NHMTWVITAFLLGQTISL 100 ++ R I+ L + S L + + +LP I + WV TAF+L +I Sbjct: 7 QSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGT 66 Query: 101 PIFGKLGDQFGRKYLFMFAIALFVVGSIIGALAQNMTT-LIVARALQGIAGGGLMILSQA 159 ++GKL DQ G K L +F I + GS+IG + + + LI+AR +QG L Sbjct: 67 AVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMV 126 Query: 160 ITADVTTARERAKYMGIMGSVFGLSSILGPLLGGWFTDGPGWRWGLWLNVPIGIIALVAI 219 + A R K G++GS+ + +GP +GG W L +P +I ++ + Sbjct: 127 VVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIH--WSYLLLIP--MITIITV 182 Query: 220 AVLLKLPARE-RGKVSVDWLGSIFMAIATTAFVLAVTWGGNEYEWASPMIIGLFITTLVA 278 L+KL +E R K D G I M++ F+L T Y I ++++ Sbjct: 183 PFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT----SYSI------SFLIVSVLS 232 Query: 279 AIVFVFVEKRAVDPLVPMGLFSNRNFVLTAVAGIGVGLFMMGTIAYMPTYLQMVHGLNPT 338 ++FV ++ DP V GL N F++ + G + + G ++ +P ++ VH L+ Sbjct: 233 FLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTA 292 Query: 339 QAGLMLI-PMMIGLIGTSTVVGNIVSKTGKYKWYPFIGMLIMILALVLLSTLTPSASLAL 397 + G ++I P + +I + G +V + G IG+ + ++ + S L + S + Sbjct: 293 EIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVL-NIGVTFLSVSFLTASFLLETTSWFM 351 Query: 398 IGLYFFVFGFGLGCAMQILVLIVQNSFPITMVGTATGSNNFFRQIGGSVGSALIGGLFIS 457 + FV G GL ++ IV +S G NF + G A++GGL Sbjct: 352 TIIIVFVLG-GLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSI 410 Query: 458 NLSDR 462 L D+ Sbjct: 411 PLLDQ 415
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 148 bits (375), Expect = 3e-41 Identities = 102/407 (25%), Positives = 184/407 (45%), Gaps = 17/407 (4%) Query: 46 VLSALMVAMMMASLDQMIFGTALPTIVGELGGV-DHMMWVITAYLLAETIMLPIYGKLGD 104 +L L + + L++M+ +LP I + WV TA++L +I +YGKL D Sbjct: 15 ILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSD 74 Query: 105 LVGRKGLFIGALGIFLIGSVIGGLAGNM-TWLIVGRAVQGIGGGGLMILSQAIIADVVPA 163 +G K L + + I GSVIG + + + LI+ R +QG G L ++A +P Sbjct: 75 QLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPK 134 Query: 164 RERGRYMGVMGGVFGLSAVLGPLLGGWFTEGPGWRWAFWMNIPLGIIAIGVAIYFLDIPK 223 RG+ G++G + + +GP +GG W++ + IP+ I + L + Sbjct: 135 ENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIH--WSYLLLIPMITIITVPFLMKLLKKE 192 Query: 224 KSVKFRWDYLGTFFMIVAATSLILFTTWGGSQYEWSDPIIIGLIITTIVAAALLVVVELR 283 +K +D G M V +LFTT Y +I ++++ + V + Sbjct: 193 VRIKGHFDIKGIILMSVGIVFFMLFTT----SYSI------SFLIVSVLSFLIFVKHIRK 242 Query: 284 AADPLVPMSFFQNRNFTLTTIAGLILGIAMFGIIGYLPTYLQMVHGINATEAGYMLI-PM 342 DP V +N F + + G I+ + G + +P ++ VH ++ E G ++I P Sbjct: 243 VTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPG 302 Query: 343 MVGMMGTSIWTGIRISNTGKYKLFPPIGMIVTFVALIFFARMEVSTTLWQIGIYLFVLGV 402 + ++ GI + G + IG+ V+ + + + +T+ + I +FVLG Sbjct: 303 TMSVIIFGYIGGILVDRRGPLYVL-NIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLG- 360 Query: 403 GLGLAMQVLVLIVQNTLPTAVVGSATAVNNFFRQIGSSLGSALVGGM 449 GL V+ IV ++L G+ ++ NF + G A+VGG+ Sbjct: 361 GLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGL 407
>SURFACELAYER#Lactobacillus surface layer protein signature. Length = 439 Score = 30.0 bits (67), Expect = 0.042 Identities = 7/39 (17%), Positives = 16/39 (41%) Query: 449 STKKVDTIVLDKTGTVTTGTMSVTDVTAINYSETEILEF 487 + LD+ G ++ + +V AI+ + + F Sbjct: 158 QPASTVKVTLDQDGVAKLSSVQIKNVYAIDTTYNSNVNF 196
>PF05272#Virulence-associated E family protein Length = 892 Score = 31.6 bits (71), Expect = 0.004 Identities = 16/54 (29%), Positives = 23/54 (42%), Gaps = 5/54 (9%) Query: 15 GKKLLDAVSLKAY-PG----EVLGLIGPNGAGKSTLLSVLSGDRLPDSGEVNVG 63 GK +L + PG + L G G GKSTL++ L G ++G Sbjct: 577 GKYILMGHVARVMEPGCKFDYSVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIG 630
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 28.8 bits (64), Expect = 0.026 Identities = 10/43 (23%), Positives = 14/43 (32%) Query: 216 APITLNLTNEVVCEDPGTPVEPETPVDPETPVDPETPVDSEEP 258 PI++ + E P P PV P P +E Sbjct: 43 QPISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEA 85
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 88.0 bits (218), Expect = 3e-22 Identities = 35/143 (24%), Positives = 69/143 (48%), Gaps = 1/143 (0%) Query: 2 TTILIVEDEESLADPLAFLLRKEGFDTIIAGDGPTALVEFSRNEIDIVLLDLMLPGMSGT 61 TIL+ +D+ ++ L L + G+D I + T + + D+V+ D+++P + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 DVCKELRSV-STVPVIMVTARDSEIDKVVGLELGADDYVTKPYSSRELIARIRAVLRRRG 120 D+ ++ +PV++++A+++ + + E GA DY+ KP+ ELI I L Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 121 VTETEAEELPLDDQILEGGRVRM 143 ++ E+ D L G M Sbjct: 124 RRPSKLEDDSQDGMPLVGRSAAM 146
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 32.5 bits (74), Expect = 0.008 Identities = 44/212 (20%), Positives = 76/212 (35%), Gaps = 39/212 (18%) Query: 179 DVAGWVGVGFTPQRYVELFTNGTDASQITIAVNDGADPMAVRNRIGKNHRDLLPLLPEQI 238 DVA V +G + NG A+ + I + GA+ + I +L P P+ + Sbjct: 264 DVAR-VELGGENYNVIARI-NGKPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGM 321 Query: 239 IDQTTGDTAR---------QLEFMTYVLLAFAAIALIVGSF------IIANTFAMIVAQR 283 DT ++L F + L + + IA ++ Sbjct: 322 KVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLL---- 377 Query: 284 TGEFALLRSIGVSTFQIGFSVIMEAVFVGLIGGFIGIAVGFGVVNALVQVLN----QFGD 339 G FA+L G+S+ +F G++ +A+G V +A+V V N D Sbjct: 378 -GTFAIL-------AAFGYSINTLTMF-GMV-----LAIGLLVDDAIVVVENVERVMMED 423 Query: 340 TLSSIDITYNAGSFIFPVLFAVTATVLSAISP 371 L + T + S I L + + + P Sbjct: 424 KLPPKEATEKSMSQIQGALVGIAMVLSAVFIP 455
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 32.0 bits (72), Expect = 0.003 Identities = 40/193 (20%), Positives = 58/193 (30%), Gaps = 36/193 (18%) Query: 14 RAAKEGRSADAPRRRRRRSIEDGGVSVAELTGSIPAVKEKPAESKHSSVPIDAPAEPE-- 71 K ++ D +I+ SV I V E P VP APA P Sbjct: 984 EVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAP-------VPPPAPATPSET 1036 Query: 72 ---VVEAPKTEPAEEVEVAS--------VEGDVDKQETPERPAP--SNEETMVLRIVDEK 118 V E K E ++ VE +V K+ A +NE E Sbjct: 1037 TETVAENSKQE-SKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKET 1095 Query: 119 DPISLTTGAFPVVPAVAAKPAPVVRAEKDADVETAVKADFAEVEVDNTDTTQMAVVEEVD 178 K V E+ A VET + +V + + + + Sbjct: 1096 QT-------------TETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQ 1142 Query: 179 EEPEQENKMSVFA 191 EP +EN +V Sbjct: 1143 AEPARENDPTVNI 1155 Score = 31.6 bits (71), Expect = 0.003 Identities = 27/190 (14%), Positives = 53/190 (27%), Gaps = 19/190 (10%) Query: 3 EEKLTVAELMARAAKEGRSADAPRRRRRRSIEDGGVSVAELTGSIPAVKEKPAESKHSSV 62 EEK V + + S +P++ + +++ + +PA +V Sbjct: 1109 EEKAKVETEKTQEVPKVTSQVSPKQEQSETVQ---------------PQAEPARENDPTV 1153 Query: 63 PIDAPAEPEVVEAPKTEPAEEVEVASVEGDVDKQETPERPAPSNEETMVLRIVDEKDPIS 122 I P A +PA+E + + T S E P Sbjct: 1154 NIKEPQSQTNTTADTEQPAKETSSNVEQ--PVTESTTVNTGNSVVENPENTTPATTQPTV 1211 Query: 123 LTTGAFPVVPAVAAKPAPVVRAEKDADVETAVKADFAEVEVDNTDTTQMAVVEEVDEEPE 182 + + P + + T+ D T T AV+ + + + Sbjct: 1212 NSESSN--KPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQ 1269 Query: 183 QENKMSVFAI 192 A+ Sbjct: 1270 FVALNVGKAV 1279
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 56.6 bits (136), Expect = 3e-13 Identities = 20/82 (24%), Positives = 39/82 (47%), Gaps = 1/82 (1%) Query: 7 RERLLDAARKRFYADGVHATGIDTITSEAGVAKKSLYNNFSSKAEIVSTYIDSRHEEWLD 66 R+ +LD A + F GV +T + I AGV + ++Y +F K+++ S + + Sbjct: 13 RQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGE 72 Query: 67 LYRQHTAK-ASTARDRVIAVLL 87 L ++ AK + +L+ Sbjct: 73 LELEYQAKFPGDPLSVLREILI 94
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 79.9 bits (197), Expect = 1e-19 Identities = 34/124 (27%), Positives = 57/124 (45%), Gaps = 1/124 (0%) Query: 3 IRVLVVDDESYLADAICTALNSAHMQATTVYDGATARSSIDDIRPDVVVLDRDLPGIHGD 62 +LV DD++ + + AL+ A + AT I D+VV D +P + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 63 DICRWVVDTHPATRVIMLTASGALDDRLAGFDLGADDYLPKPFEVSELIARV-NALAKRN 121 D+ + P V++++A + + GA DYLPKPF+++ELI + ALA+ Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 122 LPVR 125 Sbjct: 124 RRPS 127
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 38.8 bits (90), Expect = 2e-05 Identities = 25/182 (13%), Positives = 59/182 (32%), Gaps = 31/182 (17%) Query: 40 PVVSVRVDDSDPEEGVCTGTAIDRHWVITARHCIDAAAKPGGSVRIGQGDEQR------V 93 PV ++V+ + +G + + ++T +H +DA +++ + Sbjct: 89 PVTYIQVEAPTGT-FIASGVVVGKDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGG 147 Query: 94 YKVDR-HEVAPRGDIALLHTEQEINLETFAEI--------ADEVPTGD-VNIYGWSSDGS 143 + ++ + + GD+A++ + E+ E + + G+ D Sbjct: 148 FTAEQITKYSGEGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKP 207 Query: 144 GGSTKLPSAKAKVRGDSPLALYEAPKALDVALKDGDRIQPGDSGGAIF-ADGKVAGIMSA 202 + K + D G+SG +F +V GI Sbjct: 208 VATMWESKGKITYLKGEAMQY------------DLS-TTGGNSGSPVFNEKNEVIGIHWG 254 Query: 203 GL 204 G+ Sbjct: 255 GV 256
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 166 bits (423), Expect = 3e-51 Identities = 89/337 (26%), Positives = 136/337 (40%), Gaps = 45/337 (13%) Query: 8 VLVTGGTGFIGSHTVVELLNAGKQVVVIDDLSNSTIDVL---ASIEEITGSKPPLEIGDI 64 LVTG GFIG H LL AG QVV ID+L N DV A +E + D+ Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGHQVVGIDNL-NDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 65 RDRAFVDSVLAQYQPSAAIHFAAKKAVGESVEQPTMYLNINIGGTATLLDALHHAGVRDI 124 DR + + A + AV S+E P Y + N+ G +L+ H ++ + Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 125 VFSSSCSVHGETTHSPLNEDSPT-QPANPYAFTKLTGEKM---LSQLVEADESWSAISLR 180 +++SS SV+G P + D P + YA TK E M S L A LR Sbjct: 122 LYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLP----ATGLR 177 Query: 181 YFNPIGAHPSGKLGESGLGRPRNIMPWLLDVAAGRKQSLEVFGDDWPTPDGTCIRDYLHV 240 +F G GRP ++ + A +S++V+ G RD+ ++ Sbjct: 178 FFTVYGPW----------GRP-DMALFKFTKAMLEGKSIDVYN------YGKMKRDFTYI 220 Query: 241 VDVARVHVRALEHFKTGQA----------------EVFNIGTGVGTSVLELINTMEEATG 284 D+A +R + V+NIG +++ I +E+A G Sbjct: 221 DDIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALG 280 Query: 285 REIPYEISARRSGDVSALVADAQRVATQWGWVPEFSV 321 E + + GDV AD + + G+ PE +V Sbjct: 281 IEAKKNMLPLQPGDVLETSADTKALYEVIGFTPETTV 317
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 155 bits (394), Expect = 4e-47 Identities = 74/340 (21%), Positives = 128/340 (37%), Gaps = 49/340 (14%) Query: 1 MRCVITGGAGFLGSHLTDLILNQGHEVIVLDDLSTGSLSNL----FHQISNPRLQIKTVD 56 M+ ++TG AGF+G H++ +L GH+V+ +D+L+ +L ++ P Q +D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 57 VR-----KKFEIDGPVDIVFNLA-------SPASPPVYTQRRVECLLINSEAVLQVAEFA 104 + G + VF S +P Y N L + E Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADS-------NLTGFLNILEGC 113 Query: 105 LEKG-ARLVQASTSEVYGDPLSHPQLEHHWGNVNPIGERSCYDEGKRFAEALLSAMRLEQ 163 L+ AS+S VYG P + +P+ S Y K+ E + Sbjct: 114 RHNKIQHLLYASSSSVYGLNRKMPFSTDDSVD-HPV---SLYAATKKANELMAHTYSHLY 169 Query: 164 GLNAGIIRIFNTYGPRMHPFDGRVISGFVRQALANEPLTVFGDGSQTRSFCYVSDLVRGL 223 GL A +R F YGP P + F + L + + V+ G R F Y+ D+ + Sbjct: 170 GLPATGLRFFTVYGPWGRP--DMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAI 227 Query: 224 -------------WLMGN-----SNQPGPI-NLGNPIEQTVLSMAHLIKESTNSESSITF 264 W + S P + N+GN ++ ++++ E+ Sbjct: 228 IRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNM 287 Query: 265 EPLPSDDPVRRRPDISKAKELLGWEPLVGIDVGLREVINW 304 PL D + D E++G+ P + G++ +NW Sbjct: 288 LPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNW 327
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 61.4 bits (149), Expect = 4e-13 Identities = 29/112 (25%), Positives = 44/112 (39%) Query: 4 VFLVDDHSVFRSGVKAELGNAVTVVGEAGTVADAVAGIKASKPEVVLLDVHMPDGGGLAV 63 + + DD + R+ + L A V A I A ++V+ DV MPD + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 64 LQQINDSDVDTIFLALSVSDAAEDVIAIIRGGARGYVTKSISGEELVEAINR 115 L +I + D L +S + I GA Y+ K EL+ I R Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 65.6 bits (160), Expect = 4e-13 Identities = 58/291 (19%), Positives = 110/291 (37%), Gaps = 32/291 (10%) Query: 67 QEQLGDFTDSESIPAIVVMV-SDDPLTQQDIAQL-----NEVVAGLSALDIVSDEVSPA- 119 + DF D + + V + + +D+ +L N + SA Sbjct: 755 GTYVNDFIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPR 814 Query: 120 IPSEDG-RAIQVFVPLSPSAELTESVEKLSETLAQQTPDYVSTYITGPAGFTADLSAAFA 178 + +G ++++ +P + L E LA + P + TG + + Sbjct: 815 LERYNGLPSMEIQGEAAPGTSSGD-AMALMENLASKLPAGIGYDWTG---MSYQERLSGN 870 Query: 179 GIDGLLLAVALAAVLVILVIVYRSFILPIAVLATSLFALTVALLVVWWLAKWDILLLSGQ 238 L+A++ V + L +Y S+ +P++V+ + LL L Q Sbjct: 871 QA-PALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAAT---------LFNQ 920 Query: 239 TQGIL----FILVIGAATDYSLLYVARFREELRVQQDKGI--ATGKAIRASVEPILASGS 292 + + IG + ++L V F ++L ++ KG+ AT A+R + PIL + Sbjct: 921 KNDVYFMVGLLTTIGLSAKNAILIVE-FAKDLMEKEGKGVVEATLMAVRMRLRPILMTSL 979 Query: 293 TVIAGLLCLLFSDLKSNSTLGPVASV---GIIFAMLSALTLLPALLFVFGR 340 I G+L L S+ + V G++ A L A+ +P V R Sbjct: 980 AFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRR 1030 Score = 47.1 bits (112), Expect = 2e-07 Identities = 33/171 (19%), Positives = 69/171 (40%), Gaps = 17/171 (9%) Query: 544 DASIHD--RNLIIPIVLLVILVILMLLLRSIVAPLLLVVTTVVSFATALGVAALLFNHVF 601 SIH+ + L I+L + +++ L L+++ A L+ + V LG A+L + Sbjct: 334 QLSIHEVVKTLFEAIML--VFLVMYLFLQNMRATLIPTIAVPVVL---LGTFAILAAFGY 388 Query: 602 SFPGADPAVPLYGFIFLVALGIDYNIFLVTRIREETKTHGT--RLGILRGLTVTGGVITS 659 S + ++G + + L +D I +V + + + ++ G + Sbjct: 389 SI----NTLTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVG 444 Query: 660 AGVVLAATFAALYVIPIL---FLAQIAFIVAFGVLIDTLLVRAFLVPALFY 707 +VL+A F + Q + + + + ++LV L PAL Sbjct: 445 IAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL-SVLVALILTPALCA 494 Score = 36.7 bits (85), Expect = 3e-04 Identities = 30/164 (18%), Positives = 60/164 (36%), Gaps = 19/164 (11%) Query: 552 LIIPIVLLVILVILMLLLRSIVAPLLLVVTTVVSFATALGVAALLFNHVFSFPGADPAVP 611 ++ I +V+ + L L S P+ +++ + L +AA LFN Sbjct: 874 ALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVL-LAATLFNQKNDVYF------ 926 Query: 612 LYGFIFLVALGIDYNIFLVTRIREETKTHGTRLGILRGLTVTGGVITSAGVVLAATFAAL 671 + G + + L I +V ++ + G + T+ + +++ + L Sbjct: 927 MVGLLTTIGLSAKNAILIVEFAKDLMEKEGKG---VVEATLMAVRMRLRPILMTSLAFIL 983 Query: 672 YVIPILF--------LAQIAFIVAFGVLIDTLLVRAFLVPALFY 707 V+P+ + V G++ TLL F VP F Sbjct: 984 GVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLA-IFFVPVFFV 1026 Score = 36.4 bits (84), Expect = 5e-04 Identities = 35/203 (17%), Positives = 70/203 (34%), Gaps = 18/203 (8%) Query: 139 ELTESVEKLSETLAQQTPDYVSTYITGPAGFTADLSAAFAGIDGLLLAVALAAVLVILVI 198 + ++++ L P + LS I ++ + A +LV LV+ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLS-----IHEVVKTLFEAIMLVFLVM 355 Query: 199 VYRSFILPIAVLATSLFALTVALLVVWWLAKWDILLLSGQTQGILFILVIGAATDYSLLY 258 F+ + A+ V LL + + ++ T + +L IG D +++ Sbjct: 356 YL--FLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGM-VLAIGLLVDDAIVV 412 Query: 259 VARFREELRVQQDKGIATGKAIRASVE----PILASGSTVIAGLLCLLF---SDLKSNST 311 V RV + + +A S+ ++ + A + + F S Sbjct: 413 VENVE---RVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQ 469 Query: 312 LGPVASVGIIFAMLSALTLLPAL 334 + ++L AL L PAL Sbjct: 470 FSITIVSAMALSVLVALILTPAL 492
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 55.2 bits (133), Expect = 2e-10 Identities = 28/125 (22%), Positives = 48/125 (38%), Gaps = 17/125 (13%) Query: 19 RVLVTGATGYIGGRLITELLAAGFQVRA---------TSRKKTSLQRFDWYEDVEAVEAD 69 + LVTGA G+IG + LL AG QV S K+ L+ + + D Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLA-QPGFQFHKID 60 Query: 70 LTDATELDTLFKD--VDVVYYLVHSMGGKD-----VDFEEQEQLTAKNVIQAADQAGIKQ 122 L D + LF + V+ H + + + + N+++ I+ Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 123 IVYLS 127 ++Y S Sbjct: 121 LLYAS 125
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 49.6 bits (118), Expect = 6e-09 Identities = 59/247 (23%), Positives = 97/247 (39%), Gaps = 33/247 (13%) Query: 61 PERIVTLGVTDADIVLALGTVPVGNT---GYKFFENGLGPWTDELVEGKELTLLDSDSTP 117 P RIV L +++LALG VP G Y+ W E + + + P Sbjct: 35 PNRIVALEWLPVELLLALGIVPYGVADTINYRL-------WVSEPPLPDSVIDVGLRTEP 87 Query: 118 DLEQVAVLEPDLIIGVSAGFDDVVYEQLSDIAP--VVARPAGTAAYAVAREEATSLVARA 175 +LE + ++P ++ SAG+ E L+ IAP G A+AR+ T + Sbjct: 88 NLELLTEMKPSFMVW-SAGYGP-SPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLL 145 Query: 176 MGQSEKGQELNEETDALIQAARDENPSFDGKTGTVILPYQ----GKYGAYLPGDTRGQFL 231 QS L + + I++ + P F + +L + P + L Sbjct: 146 NLQSAAETHL-AQYEDFIRSMK---PRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEIL 201 Query: 232 DSLGISLPEAVLSRDTGDSFFVDVPAESVKDV----DGDVLLV-LSNDENLDITAENPLF 286 D GI P A G++ F A S+ + D DVL N +++D PL+ Sbjct: 202 DEYGI--PNAW----QGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNSKDMDALMATPLW 255 Query: 287 ETLNVVQ 293 + + V+ Sbjct: 256 QAMPFVR 262
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 37.7 bits (87), Expect = 1e-04 Identities = 35/165 (21%), Positives = 54/165 (32%), Gaps = 23/165 (13%) Query: 218 RIANQEADLVEQTQLDAN-KAAADAQVGEARAQAMQAERLADEKARL---------EVLR 267 + N E + QT N + Q + E ++A + E Sbjct: 979 DLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTE 1038 Query: 268 QQAEN-KQIELEAEVN--KVADAERYRR------KQEVEADTFEQTRRAQAQVEIAEAEA 318 AEN KQ E N + R K V+A+T + AQ+ E E + Sbjct: 1039 TVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANT-QTNEVAQSGSETKETQT 1097 Query: 319 TAAKVRAMAEAEA---VRLKGQAEADAIKAKAEAYRENQEALLAQ 360 T K A E E V + E + ++ +E E + Q Sbjct: 1098 TETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQ 1142 Score = 35.8 bits (82), Expect = 4e-04 Identities = 25/146 (17%), Positives = 50/146 (34%), Gaps = 5/146 (3%) Query: 191 LGAPEIQAKKQAAEIAETEAARAIAKSRIANQEADLVEQTQLDANKAAADAQVGEARAQA 250 A + + + E E +A A++R +EA + N+ A Q Sbjct: 1039 TVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGS-ETKETQT 1097 Query: 251 MQAERLAD----EKARLEVLRQQAENKQIELEAEVNKVADAERYRRKQEVEADTFEQTRR 306 + + A EKA++E + Q K + + ++ + + + E D + Sbjct: 1098 TETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKE 1157 Query: 307 AQAQVEIAEAEATAAKVRAMAEAEAV 332 Q+Q AK + + V Sbjct: 1158 PQSQTNTTADTEQPAKETSSNVEQPV 1183
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 39.1 bits (91), Expect = 3e-05 Identities = 35/146 (23%), Positives = 60/146 (41%), Gaps = 15/146 (10%) Query: 12 SKTGLRRN--IFAGAIGVLVHWFDWAVYAYLATTISHVFFPEQSETAALLSVFAVFAVAF 69 S++ LR N + I + V I++ F + T + + F + Sbjct: 6 SQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFML----- 60 Query: 70 FVRPLGSLIFGHLGDTLGRKKTLSLVIIMMAAGTLMLGLIPSHETIGIWAPVLLIVARVI 129 +G+ ++G L D LG K+ L II+ G+++ + S ++ LI+AR I Sbjct: 61 -TFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSL-------LIMARFI 112 Query: 130 QGIAAGGEFGSAAAFLAEYSPPKKRG 155 QG A +A Y P + RG Sbjct: 113 QGAGAAAFPALVMVVVARYIPKENRG 138
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 30.4 bits (68), Expect = 0.007 Identities = 15/32 (46%), Positives = 20/32 (62%) Query: 146 QPSSPDRPTEPTNPVDPTGPSEPSEPTEPTDP 177 QP++PD P P NP +P P EP+ P P +P Sbjct: 288 QPNNPDNPDNPNNPDNPNNPDEPNNPDNPNNP 319
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 96.1 bits (239), Expect = 3e-25 Identities = 37/127 (29%), Positives = 64/127 (50%), Gaps = 1/127 (0%) Query: 4 KILVVDDDPAISEMLTIVLSAEGFDTVAVTDGALAVETASREQPDLILLDLMLPGMNGID 63 ILV DDD AI +L LS G+D ++ A + DL++ D+++P N D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 64 ICRLIRQE-SSVPIIMLTAKTDTVDVVLGLESGADDYVNKPFKAKELVARIRARLRATVD 122 + I++ +P+++++A+ + + E GA DY+ KPF EL+ I L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 123 EPSEILE 129 PS++ + Sbjct: 125 RPSKLED 131
>SECA#SecA protein signature. Length = 901 Score = 1121 bits (2900), Expect = 0.0 Identities = 419/861 (48%), Positives = 567/861 (65%), Gaps = 46/861 (5%) Query: 4 LSKVLRVGEGRAVKRLHKIADQVIALEEKFANLTDEELKAKTAEFKERIAGGEGLDEIFL 63 L+KV R ++R+ K+ + + A+E + L+DEELK KTAEF+ R+ GE L+ + Sbjct: 6 LTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVLENLIP 65 Query: 64 EAFATAREASWRVLGQKHYRVQIMGGAALHFGNVAEMRTGEGKTLTCVLPAYLNALEGKG 123 EAFA REAS RV G +H+ VQ++GG L+ +AEMRTGEGKTLT LPAYLNAL GKG Sbjct: 66 EAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNALTGKG 125 Query: 124 VHVVTVNDYLAKRDAEMVGRVHRYLGLEVGVILSDMRPDERRKAYTADITYGTNNELGFD 183 VHVVTVNDYLA+RDAE + +LGL VG+ L M +R+AY ADITYGTNNE GFD Sbjct: 126 VHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNNEYGFD 185 Query: 184 YLRDNMARSLSDLVQRGHNYAIVDEVDSILIDEARTPLIISGPVDGTSQFYNVFAQIVPR 243 YLRDNMA S + VQR +YA+VDEVDSILIDEARTPLIISGP + +S+ Y +I+P Sbjct: 186 YLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVNKIIPH 245 Query: 244 MTK-----------DVHYEVDERKKTVGVKEEGVEYVEDQLGI-------DNLYAPEHSQ 285 + + + H+ VDE+ + V + E G+ +E+ L ++LY+P + Sbjct: 246 LIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYSPANIM 305 Query: 286 LVSYLNNAIKAQELFTRDKDYIVRNGEVMIVDGFTGRVLAGRRYNEGMHQAIEAKERVEI 345 L+ ++ A++A LFTRD DYIV++GEV+IVD TGR + GRR+++G+HQA+EAKE V+I Sbjct: 306 LMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVQI 365 Query: 346 KNENQTLATVTLQNYFRLYTKLAGMTGTAETEAAELNQIYKLDVIAIPTNRPNQREDLTD 405 +NENQTLA++T QNYFRLY KLAGMTGTA+TEA E + IYKLD + +PTNRP R+DL D Sbjct: 366 QNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPD 425 Query: 406 LVYKTQEAKFAAVVDDIAERTEKGQPVLVGTVSVERSEYLSQLLTKRGIKHNVLNAKHHE 465 LVY T+ K A+++DI ERT KGQPVLVGT+S+E+SE +S LTK GIKHNVLNAK H Sbjct: 426 LVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHA 485 Query: 466 QEAQIVAQAGLPGAVTVATNMAGRGTDIVLGGNPEILLDIKLRERGLDPFEDEESYQEAW 525 EA IVAQAG P AVT+ATNMAGRGTDIVLGG+ + + + + Sbjct: 486 NEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVA---------------ALENPT 530 Query: 526 DAELPAMKQRCEERGDKVREAGGLYVLGTERHESRRIDNQLRGRSARQGDPGSTRFYLSM 585 ++ +K + R D V EAGGL+++GTERHESRRIDNQLRGRS RQGD GS+RFYLSM Sbjct: 531 AEQIEKIKADWQVRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSM 590 Query: 586 RDDLMVRFVGPTMENMMNRLNVPDDVPIESKTVTNSIKGAQAQVENQNFEMRKNVLKYDE 645 D LM F + MM +L + IE VT +I AQ +VE++NF++RK +L+YD+ Sbjct: 591 EDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDD 650 Query: 646 VMNEQRKVIYSERREILESADISRYIQNMIEETVSAYVDG-ATANGYVEDWDLDKLWNAL 704 V N+QR+ IYS+R E+L+ +D+S I ++ E+ A +D E WD+ L L Sbjct: 651 VANDQRRAIYSQRNELLDVSDVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERL 710 Query: 705 EALYDPSINWTDLVEGSEYGKPGELSAEDLRTALVNDAHAEYAKLEEAVSAIGGEAQIRN 764 + +D + + ++ K EL E LR ++ + Y + EE V G +R+ Sbjct: 711 KNDFDLDLPIAEWLD-----KEPELHEETLRERILAQSIEVYQRKEEVV----GAEMMRH 761 Query: 765 IERMVLMPVIDTKWREHLYEMDYLKEGIGLRAMAQRDPLVEYQKEGGDMFNGMKDGIKEE 824 E+ V++ +D+ W+EHL MDYL++GI LR AQ+DP EY++E MF M + +K E Sbjct: 762 FEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYE 821 Query: 825 TVRQLFLLRKQFIKQDAEVAD 845 + L ++ ++ EV + Sbjct: 822 VISTLSKVQ---VRMPEEVEE 839
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 33.4 bits (76), Expect = 0.001 Identities = 25/154 (16%), Positives = 50/154 (32%), Gaps = 22/154 (14%) Query: 183 GRKIGITAGHC--GKSGDAVR----------SADSFWVGDTGTVVYNAPNADYSVIEFGS 230 G+ +T H GD + + D ++++F Sbjct: 110 GKDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEGDLAIVKFSP 169 Query: 231 NAELSNTYNGVTANAVGGGVTN--GQEVCKNGVATGYTCGLVWTADERMTMSQVCAGR-- 286 N + + V + Q + G +W + ++T + A + Sbjct: 170 NEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKPVATMWESKGKITYLKGEAMQYD 229 Query: 287 -----GDSGAPLI-ADGRVVGLVSGGVIPDYNLA 314 G+SG+P+ V+G+ GGV ++N A Sbjct: 230 LSTTGGNSGSPVFNEKNEVIGIHWGGVPNEFNGA 263
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 131 bits (329), Expect = 3e-36 Identities = 102/352 (28%), Positives = 167/352 (47%), Gaps = 28/352 (7%) Query: 58 GLEKVAERFQEDTGVSIRVIQRNYNGQMLSDFLTQVPTGEGPDIIVAPHDVLGQVVNNGA 117 GL +V ++F++DTG+ + V + ++ F TG+GPDII HD G +G Sbjct: 45 GLAEVGKKFEKDTGIKVTV---EHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGL 101 Query: 118 VSPVDLIDPEDNFVD----IALQAVTYDGRYYGVPFIIENVALLRNNAMTDHTPETFDDL 173 ++ I P+ F D AV Y+G+ P +E ++L+ N + + P+T++++ Sbjct: 102 LAE---ITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEI 158 Query: 174 LAEGHRLMDAGVAKYPFTTSQSEASGDPYHLYPIQSSFGAEVFKRDADGAYTAELGMGGD 233 A L G + F + PY +P+ ++ G FK + ++G+ Sbjct: 159 PALDKELKAKGKSALMFNLQE------PYFTWPLIAADGGYAFKYENGKYDIKDVGVDNA 212 Query: 234 GGHAFANYLAEMGANRDLIVTMTPDISKQAFIDGESPYFIAGPWNLPDIQAADMDIEVLS 293 G A +L ++ N+ + I++ AF GE+ I GPW +I + ++ V Sbjct: 213 GAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTV 272 Query: 294 VPSAGGQPAVPFVGVSSFMINANSSSPLAARDLALNYLSQPEVQLELFSNNQRPPANKEA 353 +P+ GQP+ PFVGV S INA S + A++ NYL E L + N+ P A Sbjct: 273 LPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDE---GLEAVNKDKPLGAVA 329 Query: 354 LESM-----GDPVLAGYARIAQEDGAPMPSIPQMGAVWNFWGITQNGIVNGA 400 L+S DP +A AQ+ G MP+IPQM A FW + ++N A Sbjct: 330 LKSYEEELAKDPRIAATMENAQK-GEIMPNIPQMSA---FWYAVRTAVINAA 377
>PF05272#Virulence-associated E family protein Length = 892 Score = 33.9 bits (77), Expect = 0.001 Identities = 24/122 (19%), Positives = 40/122 (32%), Gaps = 35/122 (28%) Query: 33 VILVGPSGCGKSTLLNMIAGLEDITGGELRFDDQVVNDFSARDRDIAMVFQSYALYPHMT 92 V+L G G GKSTL+N + GL+ + +D Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGT---------GKDSYEQIAGIVA----- 644 Query: 93 VRENIEFPLKLSRMPKSEIQDKVAEVSASLGLDEYLDRKPAQLSGGQRQRVAMGRAIVRH 152 E +++ +++ + A S+ D Y R A GR + H Sbjct: 645 ----YELS-EMTAFRRADAEAVKAFFSSR--KDRY--------------RGAYGRYVQDH 683 Query: 153 PK 154 P+ Sbjct: 684 PR 685
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 28.2 bits (62), Expect = 0.044 Identities = 16/57 (28%), Positives = 23/57 (40%), Gaps = 5/57 (8%) Query: 53 KVIIPSPAGNIPDFGILEEPTPPPTLWLPRAKSFPVDKRPIL----RTYTPSAVRPE 105 +V +PS P + P PP P + + PV +P+ T TP PE Sbjct: 399 EVTVPSTTAEAPPLILTWTPASPPGNQNPSSTT-PVVPKPVPVYEGATLTPVKATPE 454
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 28.1 bits (62), Expect = 0.037 Identities = 27/130 (20%), Positives = 44/130 (33%), Gaps = 11/130 (8%) Query: 43 SAAAKSAEESPLTQFVENSTGSQITYMSLKDDFHTG-TSTERFARPALSLAKLYIAEYVL 101 + + E + S + + DF G S E A+ K EY + Sbjct: 780 KSDSSVIVEEEINFDGTESKDEDGEIKAYEWDFGDGEKSNE--AKATHKYNK--TGEYEV 835 Query: 102 EHGTNNEKSL---AMEMIKDSSDVSAEILYESYPNSIEEIADQYGLLSTRGDAHW---GY 155 + + + IK D E++ ES PN+ E A+Q + Y Sbjct: 836 KLTVTDNNGGINTESKKIKVVEDKPVEVINESEPNNDFEKANQIAKSNMLVKGTLSEEDY 895 Query: 156 SVTSTYDLAK 165 S +D+AK Sbjct: 896 SDKYYFDVAK 905
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 100 bits (250), Expect = 2e-27 Identities = 59/185 (31%), Positives = 89/185 (48%), Gaps = 6/185 (3%) Query: 4 KVALVTGASSGIGESTARKLQSLGFTVYGATRRTERLQKLASD----GIHP--LEMDVTD 57 K+A +TGA+ GIGE+ AR L S G + E+L+K+ S H DV D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 58 DESMKARIAKILADSGRIDVLVNNAGYGSYGAIEDVSIDEGGRQFEVNVFGAMALTRLVL 117 ++ A+I + G ID+LVN AG G I +S +E F VN G +R V Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 118 PHMRKQKSGTIVNITSMGGKIYTPLGGWYHGTKFALEALSDALRLEVAQFGIDVVVIEPG 177 +M ++SG+IV + S + Y +K A + L LE+A++ I ++ PG Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 178 GIATE 182 T+ Sbjct: 189 STETD 193
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 61.6 bits (149), Expect = 4e-14 Identities = 25/161 (15%), Positives = 54/161 (33%), Gaps = 9/161 (5%) Query: 5 KPMRADAVRNRRKILDAACEQTTVHGPD-VGMDEIAAAAEVAVGTLYRHFPTKKSLLAAV 63 + + +A R+ ILD A + G + EIA AA V G +Y HF K L + + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 64 IAEHVAKV-AVDAEASLTRAADGSAAVDEVVGFLSRVADSSANNHAVKA-------AAKS 115 + + ++ E D + + E++ + + + Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 116 LGVSEYGDQSDEARASAALASLIALGQEAGDIRQGITVDDF 156 + V + ++ + + + EA + + Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRA 163
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 65.6 bits (160), Expect = 1e-13 Identities = 70/331 (21%), Positives = 120/331 (36%), Gaps = 37/331 (11%) Query: 31 TLFTLAILSAVAPFSIDLYLPAFPAMTEDLHTTAT-----GVQLSLTAFLIGAGVGQVVF 85 L + A+ I L +P P + DL + G+ L+L A + Q Sbjct: 6 PLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALM------QFAC 59 Query: 86 GP----LSDRIGRLIPLYIGLVLFLVASIVTVFASNVEILVAARLAQGLGGASGMVIGRA 141 P LSDR GR L + L V + A + +L R+ G+ GA+G V G A Sbjct: 60 APVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAG-A 118 Query: 142 MVLDKEKGAAAAKALSIMMVIGGIAPVVAPLAGSLLADLIGWRGLLAIVAGIGVVGIAST 201 + D G A+ M G V P+ G L+ A + + + Sbjct: 119 YIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFAAAALNGLNFLTG 177 Query: 202 VFFIRETLPKSQRSHSAQASTSKPIKALAFRGYIGNVVAFAFAMAILMSYISASP----- 256 F + E+ +R +A P+ + + + VVA A+ +M + P Sbjct: 178 CFLLPESHKGERRPLRREA--LNPLASFRWARGM-TVVAALMAVFFIMQLVGQVPAALWV 234 Query: 257 FVYQNMIGLDAVGYGFAFAV----NAIGITVLTGISARLTGRVTTFALTLIGLSTSFIAI 312 ++ DA G + A +++ ++TG A G L +I T +I + Sbjct: 235 IFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILL 294 Query: 313 VVISILTFSSAPASWLMVPLFCAIAPLGLVL 343 + W+ P+ +A G+ + Sbjct: 295 AFAT--------RGWMAFPIMVLLASGGIGM 317
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.9 bits (64), Expect = 0.049 Identities = 13/33 (39%), Positives = 17/33 (51%) Query: 39 ILLTGASGAGKSTLLAALAGVLGGSDEGVSTGE 71 ++L G G GKSTL+ L G+ SD G Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGT 631
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 29.0 bits (65), Expect = 0.018 Identities = 21/74 (28%), Positives = 31/74 (41%), Gaps = 14/74 (18%) Query: 60 LFLMA-PVAALS-MALYGRPDGKEYFSFLLIHVTDNSLALAAAIGLRVLAIGLPVVVLIA 117 L L A PVAA++ + LYG S + H + + G +V L + Sbjct: 8 LTLAALPVAAMADVTLYGTIKAGVETSRSVAHNGAQA---------ASVETGTGIVDLGS 58 Query: 118 RI---DPTDLGDGL 128 +I DLG+GL Sbjct: 59 KIGFKGQEDLGNGL 72
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 30.3 bits (68), Expect = 0.019 Identities = 15/90 (16%), Positives = 25/90 (27%), Gaps = 1/90 (1%) Query: 500 RPAPTTNSPIIALPPTWIIGPEDPESTDPTAPTEPTEPSEPVATDEPSETSEQTSPLLAP 559 PAP + + P + P+ + P EP EP+ P P Sbjct: 43 LPAPAQPISVTMVAPADLEPPQAVQP-PPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKP 101 Query: 560 STTPETEPETTEAPVETTEASSEITVSEVN 589 P+ + + + S N Sbjct: 102 KPKPKPVKKVEQPKRDVKPVESRPASPFEN 131
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 29.2 bits (65), Expect = 0.009 Identities = 20/84 (23%), Positives = 35/84 (41%), Gaps = 1/84 (1%) Query: 67 IQRAEAAQAEAKAALEKYNAQLAEARTEAAEIREQARERGKQIEAELKDKANEESNRIIE 126 I ++E + K + Q + +Q KQI A L D+ + + Sbjct: 133 IGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQI-ASLNDQISRLTGVGAG 191 Query: 127 SGSKQLLAQREQVVNELRREMGQN 150 + LL QR+Q+V+EL + +G Sbjct: 192 ASPNNLLDQRDQLVSELNQIVGVE 215
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 45.8 bits (108), Expect = 2e-08 Identities = 15/65 (23%), Positives = 30/65 (46%) Query: 16 RLAEIIDTAWRLVETRGWANVSMRTLAAELNIKAPSLYKHVKTREDIAAHIATKAFIQLG 75 I+D A RL +G ++ S+ +A + ++Y H K + D+ + I + +G Sbjct: 12 TRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIG 71 Query: 76 QSLHE 80 + E Sbjct: 72 ELELE 76
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 28.6 bits (64), Expect = 0.004 Identities = 9/19 (47%), Positives = 14/19 (73%) Query: 30 ATELGVNRNTLQNWLKKYG 48 A LG+NRNTL+ +++ G Sbjct: 456 ADLLGLNRNTLRKKIRELG 474
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 27.8 bits (62), Expect = 0.031 Identities = 10/16 (62%), Positives = 10/16 (62%) Query: 124 AVFAGNTIHAVHTAGA 139 A G TIHA HT GA Sbjct: 263 AAIKGRTIHAYHTEGA 278
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 28.7 bits (64), Expect = 0.042 Identities = 21/115 (18%), Positives = 46/115 (40%), Gaps = 8/115 (6%) Query: 97 SSNGYDGRVSIEVDPRISA----DRDATLAQAKELWAKVDRPNVMIKIPATPGSLPAITD 152 ++ + +E DP ++A D + + L +D+P+ I++ + + A D Sbjct: 237 AATRASAQARVEADPSLNAIIVRDSPERMPMYQRLIHALDKPSARIEVALSIVDINA--D 294 Query: 153 ALAEGISVNVTLIFSVARYREVIAAFIEGIKQAAANGHDVSKIH-SVASFFVSRV 206 L E + V+ + +V+ A+NG S + + ++RV Sbjct: 295 QLTE-LGVDWRVGIRTGNNHQVVIKTTGDQSNIASNGALGSLVDARGLDYLLARV 348
>SECGEXPORT#Protein-export SecG membrane protein signature. Length = 110 Score = 37.2 bits (86), Expect = 7e-07 Identities = 18/73 (24%), Positives = 40/73 (54%), Gaps = 1/73 (1%) Query: 1 MALTLQIILVVASLLMTVFVLLHKGKGGGLSSLFGGGVQSNLSGSTVVEKNLDRVT-ILV 59 M L ++ ++ ++ + ++L +GKG + + FG G + L GS+ + R+T +L Sbjct: 1 MYEALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFGSSGSGNFMTRMTALLA 60 Query: 60 AVIWIVCIVALNL 72 + +I+ +V N+ Sbjct: 61 TLFFIISLVLGNI 73
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.4 bits (68), Expect = 0.009 Identities = 36/247 (14%), Positives = 87/247 (35%), Gaps = 24/247 (9%) Query: 23 NADPKVQIQQAIEDAQRQHQEL---SQQAAAVIGNQRQ------LEMQLNRRLAEIEKLQ 73 A P + E+++++ + + Q A R+ ++ N + E+ + Sbjct: 1030 PATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSG 1089 Query: 74 GNTRQAIQLADKARADGDVKKATEYENAAEAFAAQL---VTAEQSVEDTKQLHDQALQQA 130 T++ K A + ++ + E ++ V+ +Q +T Q + ++ Sbjct: 1090 SETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPAREN 1149 Query: 131 DQA----KKAVERNSMALQQKVAERTK-----LLSQLEQAKMQEKVSESLKSMDSLTSGS 181 D + + N+ A ++ A+ T +++ V E+ ++ T+ Sbjct: 1150 DPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQP 1209 Query: 182 TPNLD---QVREKIERRYANALGQAELASNSVEGRMAEVEQAGVQMAGHSRLEQIRAEMA 238 T N + + + + R + E A+ S R ++ L RA+ Sbjct: 1210 TVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQ 1269 Query: 239 GGSLTAG 245 +L G Sbjct: 1270 FVALNVG 1276
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 27.4 bits (60), Expect = 0.029 Identities = 14/44 (31%), Positives = 22/44 (50%), Gaps = 1/44 (2%) Query: 12 NPNDLPTGLDPAYEGNSELNPLGGKNIPDEPEVTANTPAVQEEP 55 PN+ P G P E + +LNP + +P ++PAV + P Sbjct: 342 APNENP-GTRPNPEPDPDLNPDANPDTDGQPGTRPDSPAVPDRP 384
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 70.7 bits (173), Expect = 4e-16 Identities = 58/264 (21%), Positives = 102/264 (38%), Gaps = 31/264 (11%) Query: 51 SSSDEQRIVALNTGQLDNLLLLGITPVGVAAAKNSDLIPQFLKDRFSADMDL-DSIADCG 109 ++ D RIVAL ++ LL LGI P GVA N L + ++ L DS+ D G Sbjct: 31 AAIDPNRIVALEWLPVELLLALGIVPYGVADTINYRL--------WVSEPPLPDSVIDVG 82 Query: 110 LRQSPDIEAIANLNPTLICANSRADEEVLNKLRTIAPVVTGEG--GGEN------WKQDL 161 LR P++E + + P+ + ++ +A + G G + ++ L Sbjct: 83 LRTEPNLELLTEMKPSFMVWSAGYGP----SPEMLARIAPGRGFNFSDGKQPLAMARKSL 138 Query: 162 LTIAEAAGQKEKAETLLKSYEDSAAEIAANQPAN--PPTVSFLRTKDQEFQMYGAQSMAG 219 +A+ + AET L YED + P + + ++G S+ Sbjct: 139 TEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQ 198 Query: 220 TVAADCGYARPENQQFTDTAGQDLSAE-LIAQADADWLFYGMKEGNINP--EDTPLWTSL 276 + + G + +S + L A D D L + TPLW ++ Sbjct: 199 EILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNSKDMDALMATPLWQAM 258 Query: 277 KAVQSNQ--AIPVDGDSWYLNASL 298 V++ + +P W+ A+L Sbjct: 259 PFVRAGRFQRVP---AVWFYGATL 279
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 27.3 bits (60), Expect = 0.023 Identities = 20/81 (24%), Positives = 27/81 (33%), Gaps = 5/81 (6%) Query: 56 PTVTQTVTQTTTATPATRTVTTTVEPTTEEPVQEEVEPAAVEVEE-EPAPAPTNNVNAPQ 114 V A + T T T E E+ E A VE E+ + P T+ V+ Q Sbjct: 1074 SNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQ 1133 Query: 115 RAASI----PEPAPAPAPAAA 131 + EPA P Sbjct: 1134 EQSETVQPQAEPARENDPTVN 1154
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 28.5 bits (63), Expect = 0.015 Identities = 22/113 (19%), Positives = 40/113 (35%), Gaps = 8/113 (7%) Query: 62 RQAAENVAESLSKGMRVIVTGRLKQRSYETREGEKRSVFEVEADEVGPSLTFAYANVHRQ 121 R+ A+ ++ + + + ET+ E + VE +E T + Sbjct: 1066 REVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVET-------EK 1118 Query: 122 TGKQSGQQASQPPAQAANESRGGFGQAAPASDP-WNSAPPAGSGGFGADQDQP 173 T + + P Q +E+ + A +DP N P AD +QP Sbjct: 1119 TQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQP 1171
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 26.3 bits (58), Expect = 0.014 Identities = 19/70 (27%), Positives = 30/70 (42%), Gaps = 9/70 (12%) Query: 14 MKKTITPKLLLDLLAIGSVDLELWGQSEIAKLVGAGM---RSEGYALAKVWSPEIRREVI 70 MKK++ L L D+ L+G + AG+ RS + A+ S E ++ Sbjct: 1 MKKSLIALTLAALPVAAMADVTLYGT------IKAGVETSRSVAHNGAQAASVETGTGIV 54 Query: 71 DLVAITDIKG 80 DL + KG Sbjct: 55 DLGSKIGFKG 64
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 117 bits (295), Expect = 1e-33 Identities = 80/258 (31%), Positives = 126/258 (48%), Gaps = 19/258 (7%) Query: 48 LKGRKALITGGDSGIGAAVAIAYAREGADVSIA-YLPEEQADADRVLHAIEETGQKAFSF 106 ++G+ A ITG GIG AVA A +GA ++ Y PE+ ++V+ +++ + A +F Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKL---EKVVSSLKAEARHAEAF 62 Query: 107 PGDLRDPEYCRSLVQETVNALGGLDILVNNASRQVWAPGLT-EITDENFDQTLQVNLYGS 165 P D+RD + +G +DILVN A V PGL ++DE ++ T VN G Sbjct: 63 PADVRDSAAIDEITARIEREMGPIDILVNVAG--VLRPGLIHSLSDEEWEATFSVNSTGV 120 Query: 166 FRVTKAAIPHLKP--GSSIIFTSSIQAYQPSETLLDYAMTKAALNNLSKGLASSLIGDGI 223 F +++ ++ SI+ S A P ++ YA +KAA +K L L I Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNI 180 Query: 224 RVNSVAPGPFWTPLQPS-----HGQPQEKIEGFGQH----APIGRAGHPVELAGAYVFLA 274 R N V+PG T +Q S +G Q I+G + P+ + P ++A A +FL Sbjct: 181 RCNIVSPGSTETDMQWSLWADENGAEQ-VIKGSLETFKTGIPLKKLAKPSDIADAVLFLV 239 Query: 275 SDEASYVVGETLGVTGGT 292 S +A ++ L V GG Sbjct: 240 SGQAGHITMHNLCVDGGA 257
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 30.7 bits (69), Expect = 0.009 Identities = 21/61 (34%), Positives = 24/61 (39%), Gaps = 6/61 (9%) Query: 260 RLEYQDMINTLAAADIFAMPARTRGGGLDVEGLGIVYLEAQACGVPVIAGTSGGAPETVT 319 RLEYQ N D + R G L LG+ Y Q PV+A APE T Sbjct: 159 RLEYQWTNN---IGDAHTIGTRPDNGML---SLGVSYRFGQGEAAPVVAPAPAPAPEVQT 212 Query: 320 P 320 Sbjct: 213 K 213
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 35.4 bits (81), Expect = 3e-04 Identities = 36/170 (21%), Positives = 66/170 (38%), Gaps = 4/170 (2%) Query: 39 EEVDQLIADIEHVSQETSAQNEAVKQLEIDIEAREVTIKEVQEQSVSYREAADQASENVE 98 A I+ + E +A LE + + ++ + REA Q Sbjct: 274 NFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEH- 332 Query: 99 AYRSEINRIAQAKYRGTVTDPLSIAVSAEDPQNVIDRMSYLSTLTKSTSDVVESLNAETE 158 E N+I++A + D + S E + + L K + +SL + + Sbjct: 333 QKLEEQNKISEASRQSLRRD---LDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLD 389 Query: 159 KSAEAVYQANRTKAEAEFQLGQLKVRQAELESEKEALDGRKSEIRDRVDA 208 S EA Q + EA +L L+ ELE K+ + K+E++ +++A Sbjct: 390 ASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEA 439
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 27.2 bits (60), Expect = 0.049 Identities = 29/150 (19%), Positives = 48/150 (32%), Gaps = 19/150 (12%) Query: 71 LSSQAAPTAYAAVIDAPAAEAQAAPAASTGQAIVDAARTKIGSPYGWGATGPNA---FDC 127 LS+Q AP A + P + Q + + + G +T N ++ Sbjct: 315 LSNQPAPPNEAPIATPPTNQQN-------AQNTPQTSTSTNSNSAGPRSTQRNETSNYEV 367 Query: 128 SGLTSWAYSQVGKSIPRTS------QAQAAQGTPVAYSDLQAGDIVAFYSGATHVGIYSG 181 VG I R S A G P+ + Q I A +G Sbjct: 368 DRTIRHTKMNVGD-IERLSVAVVVNYKTLADGKPLPLTADQMKQIEDLTREA--MGFSDK 424 Query: 182 HGTVIHALNSSTPLSEHSLDYMPFHSAVRF 211 G ++ +NS +++ +PF F Sbjct: 425 RGDTLNVVNSPFSAVDNTGGELPFWQQQSF 454
>PF08280#M protein trans-acting positive regulator Length = 530 Score = 33.3 bits (76), Expect = 9e-04 Identities = 8/31 (25%), Positives = 13/31 (41%) Query: 25 DNPSQTLSEVASQTGLSRATARRFLHTLTDL 55 S ++EVA +TGL+ + L Sbjct: 55 KTSSLPITEVAEKTGLTFLQLNHYCEELNAF 85
>PF06580#Sensor histidine kinase Length = 349 Score = 32.9 bits (75), Expect = 0.002 Identities = 29/176 (16%), Positives = 68/176 (38%), Gaps = 26/176 (14%) Query: 259 ERASEIVSSVKRYVRR--IESATSVFDLNRE---VEESLYFARLRAEEKGVLILDDLLPD 313 +A E+++S+ +R S L E V+ L A ++ E++ L ++ + Sbjct: 191 TKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDR--LQFENQINP 248 Query: 314 ELLIEGESVLIGQVIINICMNALEEVILPTTEEKVMELRTESDGNTVSILVCDQGRGIEG 373 ++ ++ Q ++ N ++ I + + L+ D TV++ V + G Sbjct: 249 AIMDVQVPPMLVQTLVE---NGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTG----- 300 Query: 374 VPADRLAAGAFSSKEDGSGIGLI-ISEHIVQRHGG--HITYEPNQPRGTKVRITLP 426 + A + ++ +G GL + E + +G I + + +P Sbjct: 301 -------SLALKNTKESTGTGLQNVRERLQMLYGTEAQIKLS-EKQGKVNAMVLIP 348
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 97.8 bits (243), Expect = 1e-26 Identities = 71/252 (28%), Positives = 110/252 (43%), Gaps = 11/252 (4%) Query: 7 KIALVTGAAGGLGSFITKKLHADGHKVVVTGRSFEPLQELANELSADGSTALPLQLDVSH 66 KIA +TGAA G+G + + L + G + + E L+++ + L A+ A DV Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 67 KDNFLNALDQVKDVWGTPSILVNNAAVTRAANVLELNTEEFDEVLTTNVNSIFFGCQVFG 126 +++ G ILVN A V R + L+ EE++ + N +F + Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 127 IAMAEQGYGRIVNQASLAGQNGGTATGAHYAASKGAILTTTKVFAREFAGSGVTVNAISP 186 M ++ G IV S T+ A YA+SK A + TK E A + N +SP Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAA-YASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 187 GPHDVDIVHTTVADH----------LEQIVEGIPVKQLGNPQFIANTVSLLTQPEASFVT 236 G + D+ + AD LE GIP+K+L P IA+ V L +A +T Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHIT 247 Query: 237 GACWDINGGLYL 248 ++GG L Sbjct: 248 MHNLCVDGGATL 259
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 90.3 bits (224), Expect = 2e-23 Identities = 27/120 (22%), Positives = 51/120 (42%) Query: 8 VYIVDDDVEVCESVAWLLESASIESTICHSAQELLDSFDDTKPACLILDVRMPSMSGIRL 67 + + DDD + + L A + I +A L ++ DV MP + L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 68 QEKLNELSPHVVVIFVSAHGDIRMSVDTIKAGAQDFLEKPYDSQRLLDAVQLGIESAERR 127 ++ + P + V+ +SA ++ + GA D+L KP+D L+ + + +RR Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRR 125
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 38.7 bits (90), Expect = 4e-05 Identities = 75/402 (18%), Positives = 138/402 (34%), Gaps = 64/402 (15%) Query: 35 VVFLLVIFQIIAFADKAVLGLVSTDAMAELGLTPTQFGMIGSSFFLLYSIVSIVTGVIAS 94 ++ L I + ++ VL + D + P + ++F L +SI + V G ++ Sbjct: 15 ILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSD 74 Query: 95 RVSVHWIVLTLGVIWAVMQFPMLLG-GGAAVLLATRIIL--GGAEGPATAMSLTSAHTWF 151 ++ + ++L +I +G ++L+ R I G A PA M + + + Sbjct: 75 QLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPK 134 Query: 152 KPKERALP--SSLIAAGSTLGPIIAAPVLTLVITAWGWRWAFGVLGIVGLVWCVSWLFFG 209 + + +A S++A G +GP I + + W + ++ I+ Sbjct: 135 ENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYI--HWSYLLLIPMITIIT----------- 181 Query: 210 GSGPFLANKKQQVVTDNAKNIEQAPVAKESSVDDQPSFPIWRVLLSVSFLAALVGATSNF 269 PFL + K+ +L+SV + ++ TS Sbjct: 182 --VPFLMK-----------------LLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYS 222 Query: 270 FVQGFLTTWLPQYLETVVGL-----PLTQVGVVTTFPWIIGALV--LLTLGAIGDRMMRR 322 FL + +L V + P G+ P++IG L ++ G M Sbjct: 223 I--SFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVP 280 Query: 323 GLTARISIAALFGLSTTVAGISFLLVTVTSGTIS---VAFLAIAGGCSLVFPMAATAVS- 378 + + LST G + S I L G V + T +S Sbjct: 281 YMMKDV-----HQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV 335 Query: 379 ---------YCVGVKQRPIIMATLGGLAATGAIISPTLVGSL 411 II+ LGGL+ T +IS + SL Sbjct: 336 SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSL 377
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 42.5 bits (100), Expect = 2e-06 Identities = 30/145 (20%), Positives = 55/145 (37%), Gaps = 21/145 (14%) Query: 68 LAVFAVGFVMRPLGGFVFGRIADRKGRKWVLLVTMLMMASGSLLIGIIPSYETIGGFASF 127 LA++A+ M+ V G ++DR GR+ VLLV++ A ++ P Sbjct: 49 LALYAL---MQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLW-------- 97 Query: 128 LLLLARLIQGFAHGGEATASNVYLPEIAPRHRRALYGSTIGFAMGLGTMIAILFGSVLTN 187 +L + R++ G G + Y+ +I RA + + G G + + G ++ Sbjct: 98 VLYIGRIVAGIT-GATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG 156 Query: 188 IFDSAVMNEWGWRIPFIFGGLLAVV 212 PF L + Sbjct: 157 F---------SPHAPFFAAAALNGL 172
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 29.8 bits (67), Expect = 0.009 Identities = 16/73 (21%), Positives = 25/73 (34%), Gaps = 9/73 (12%) Query: 62 VISID-----WAQVDPSRPLETDDLVEQVTTTIQHLLPGQQVVLLGYSLGA-VIAAKIAA 115 V+ W Q DP + + Q Q+V+L+GYS GA VI + Sbjct: 81 VVGWSSLKYYWKQKDPK---DVTQDTLAIIDKYQAEFGTQKVILIGYSFGAEVIPFVLNE 137 Query: 116 DHPDLVDRLILVS 128 ++ Sbjct: 138 MPARYRKNVLGAV 150
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 92.0 bits (228), Expect = 3e-24 Identities = 72/266 (27%), Positives = 117/266 (43%), Gaps = 19/266 (7%) Query: 10 NVEKVVRPVALVTGGRQGLGLGAAKGLALRGFDVAIVDLPEPDQATDLVLNELRKLGATT 69 N + + +A +TG QG+G A+ LA +G +A VD + V++ L+ Sbjct: 2 NAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKL--EKVVSSLKAEARHA 59 Query: 70 RYYQLDISEVERHQEIIDQIWEDFGRLDCLHNNAGIAARPLTDILQLTPDAFDRAVDINL 129 + D+ + EI +I + G +D L N AG+ L L+ + ++ +N Sbjct: 60 EAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIH--SLSDEEWEATFSVNS 117 Query: 130 RGTFFLSQTVANRMVEDPDRFSDGIYRSIIIVTSIAAELVSPDRAQYNITKAGLSMLTKI 189 G F S++V+ M+ DR S SI+ V S A + A Y +KA M TK Sbjct: 118 TGVFNASRSVSKYMM---DRRSG----SIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKC 170 Query: 190 LAYRLGPEGIAVHEIRPGFMHTAMTASAGSPE------IEAAIADGR--VPLSRWGNPDD 241 L L I + + PG T M S + E I+ ++ + +PL + P D Sbjct: 171 LGLELAEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSD 230 Query: 242 ISTAVGTLASGDLPYMTGQPIWIAGG 267 I+ AV L SG ++T + + GG Sbjct: 231 IADAVLFLVSGQAGHITMHNLCVDGG 256
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 42.8 bits (100), Expect = 2e-06 Identities = 78/346 (22%), Positives = 136/346 (39%), Gaps = 51/346 (14%) Query: 49 EIAKAYTEETGVKVKVVTAASGSYEQTLKAEIGKDEAP-TLFQVNGPAGFITWQDYMADM 107 E+ K + ++TG+KV V E+ + P +F + G +A++ Sbjct: 48 EVGKKFEKDTGIKVTV--EHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEI 105 Query: 108 SDTEVAKQLTDDIPPLTTE----DGEVRGVPFAVEGFGIIYNDEIFDKYIATSGAKIKST 163 + K D + P T + +G++ P AVE +IYN ++ K+ Sbjct: 106 TPD---KAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPN-------PPKTW 155 Query: 164 DEITSYQKLKEVAEDMQAKKDELGIEGAFASTSLTSGEDWRWQTHLANAPIWQEYQDKGV 223 +EI + K EL +G A + W A+ +Y++ G Sbjct: 156 EEIPALDK-------------ELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYEN-GK 201 Query: 224 EDTNEIEFSYNKEYKNLFDLYLENSTVEKSLAPSKTVSDSMAEFAQGKAAMVQNGNWAWS 283 D ++ L +L + K + S + A F +G+ AM NG WAWS Sbjct: 202 YDIKDVGVDNAGAKAGL--TFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWS 259 Query: 284 QISETSGNVVKEDKIKFLPMYMGLPDEEKHGINVGTENYLGVNSEASEVDQQATKDFVDW 343 I + N + LP + G P + G+ L A+ +++ K+F++ Sbjct: 260 NIDTSKVNY----GVTVLPTFKGQPSKPFVGV-------LSAGINAASPNKELAKEFLEN 308 Query: 344 LFTSEAGKEHVVKD--LGFIAPFESYTAEDTPNDPLAEQVAEAIAN 387 ++ G E V KD LG +A +SY E+ DP ++A + N Sbjct: 309 YLLTDEGLEAVNKDKPLGAVA-LKSYE-EELAKDP---RIAATMEN 349
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 117 bits (295), Expect = 4e-34 Identities = 73/256 (28%), Positives = 117/256 (45%), Gaps = 12/256 (4%) Query: 3 KVAMVTGGAQGIGRGISEKLAADGFDIAVADLPQQEEQAAETIKLVEAAGQKSVFVGLDV 62 K+A +TG AQGIG ++ LA+ G IA D ++ + + EA ++ DV Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAF--PADV 66 Query: 63 TDKANFDSAIDEAAEKLGGFDVLVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVFFGIQA 122 D A D ++G D+LVN AG+ + + +++E+ + +SVN VF ++ Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 123 ASRKFDELGVKGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQAAAQELAPKGHTVNAY 182 S+ + G I+ S A ++AY+++K A T+ ELA N Sbjct: 127 VSKYMMDRR-SGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 183 APGIVGTGM----WEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFLAS 238 +PG T M W + I G E FK + I L + + P D+A V FL S Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGS--LETFK---TGIPLKKLAKPSDIADAVLFLVS 240 Query: 239 ENSNYVTGQVMLVDGG 254 + ++T + VDGG Sbjct: 241 GQAGHITMHNLCVDGG 256
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 96.3 bits (239), Expect = 6e-26 Identities = 66/254 (25%), Positives = 107/254 (42%), Gaps = 17/254 (6%) Query: 6 VLITAGAGGIGWAIAQAFLNTNSLVHIVDVSPEAVEKVAGSHDNLSTSI----GDVTSVE 61 IT A GIG A+A+ + + + VD +PE +EKV S + DV Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSA 70 Query: 62 DIATLASDLENRWGGLDVLVSNAGIAGPTAPVEEYDADAWKSVMDINLTGSFNVVQHFVP 121 I + + +E G +D+LV+ AG+ P + + W++ +N TG FN + Sbjct: 71 AIDEITARIEREMGPIDILVNVAGVLRP-GLIHSLSDEEWEATFSVNSTGVFNASRSVSK 129 Query: 122 LLKTS-GGSILIMSSLAGRFGYPNRIAYSTSKWGLIGFTKTLSLELGPFGITVNSIHPGA 180 + GSI+ + S + AY++SK + FTK L LEL + I N + PG+ Sbjct: 130 YMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGS 189 Query: 181 VNGPRLEQVFAARAEVSGRSVEAEVEAGLANQ-----SIKKFTDPEDIAALAVFLAGPHS 235 ++A + +V G +KK P DIA +FL + Sbjct: 190 TETDMQWSLWAD------ENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 236 RTISGQQFPIDGDS 249 I+ +DG + Sbjct: 244 GHITMHNLCVDGGA 257
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 67.2 bits (164), Expect = 3e-14 Identities = 85/404 (21%), Positives = 137/404 (33%), Gaps = 59/404 (14%) Query: 31 TVTIALLMVVLDGFEVGIMAFAAPQIQEQLGISPDI---LGYVLSGSLFGMAIGSIFLTP 87 + + L V LD +G++ P + L S D+ G +L+ + L Sbjct: 6 PLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGA 65 Query: 88 LADRFGRRPLTLAMLTLIVVGMALTLTAPTALWLIVWRIVTGLGIGGMMANLNALVAEYS 147 L+DRFGRRP+ L L V A+ TAP L + RIV G+ G A A +A+ + Sbjct: 66 LSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGI-TGATGAVAGAYIADIT 124 Query: 148 SDKRRTTAI----AIYAAGYPIGATVAGFIARPLIPQYGWHSMFIAGTILAVVALIGAFA 203 R A + G G + G + + H+ F A L + + Sbjct: 125 DGDERARHFGFMSACFGFGMVAGPVLGGLMG-----GFSPHAPFFAAAALNGLNFLTGCF 179 Query: 204 LLPESLDYLLGRRPNRALDRVNKILGKMNVAPLDALPERTNTEEDRVSTKNTIREVLSPP 263 LLPES ER + ++ + R Sbjct: 180 LLPESHK-----------------------------GERRPLRREALNPLASFRWARGMT 210 Query: 264 TLRLTMALWLGYALLVAAYYFANTWIPTILTNVSGDPQLGTTMGIGANLGGVLGCF---- 319 + MA++ L+ A W+ D TT+GI G+L Sbjct: 211 VVAALMAVFFIMQLVGQV--PAALWVIFGEDRFHWDA---TTIGISLAAFGILHSLAQAM 265 Query: 320 VFAALAIRFSGRHLLFITLFAAAAAYIIF---GMVFSIIPVAIMVGFVLGVLTTGAIAGF 376 + +A R R L + + A YI+ + P IMV G + A+ Sbjct: 266 ITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFP--IMVLLASGGIGMPALQAM 323 Query: 377 YAVAPTIYSSKARATGIGWMIGIGRLVSVAAPIIVGYILAAGAE 420 + + + G + + L S+ P++ I AA Sbjct: 324 LS---RQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASIT 364
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 44.8 bits (106), Expect = 5e-07 Identities = 42/159 (26%), Positives = 65/159 (40%), Gaps = 25/159 (15%) Query: 145 ILGPLGDKVGRQKVLYVTMAMMAISTALIGVLPTAASIGAWALILLYLLKMIQGFSTGGE 204 +LG L D+ GR+ VL V++A A+ A++ P L +LY+ +++ G TG Sbjct: 62 VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPF--------LWVLYIGRIVAGI-TGAT 112 Query: 205 YAGATTYVAEFAP-DRRRGYFGSFLDMGSYLGFAAGASVVAITTWVTTHYWGASAMEDFG 263 A A Y+A+ D R +FG F+ G AG + M F Sbjct: 113 GAVAGAYIADITDGDERARHFG-FMSACFGFGMVAGPVL-------------GGLMGGFS 158 Query: 264 WRIPFLTAIPLGIIA-VYLRTRIPETPAFENNQDEDEAV 301 PF A L + + +PE+ E EA+ Sbjct: 159 PHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREAL 197 Score = 41.7 bits (98), Expect = 5e-06 Identities = 37/172 (21%), Positives = 64/172 (37%), Gaps = 22/172 (12%) Query: 347 MPVYLEEQIGLHSASAAAVTVPIL----VVMSLLLPFVGMWSDRVGRKPVYATAVAATLI 402 +P L + + HS A +L ++ P +G SDR GR+PV + +L Sbjct: 28 LPGLLRDLV--HSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPV----LLVSLA 81 Query: 403 LMVPAFLIMNTGTIGAVLIALSMVAIPTGLYVALSASALPALFPTASRFSGMG-ISYNIS 461 + IM T VL +VA TG A++ + + + R G +S Sbjct: 82 GAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFG 141 Query: 462 VSLFGGTTPLITQFLLQKTGLDIVPALYIMFFSAIAGVALL----FMTESSQ 509 + G P++ + P +A+ G+ L + ES + Sbjct: 142 FGMVAG--PVLGGLMGG-----FSPHAPFFAAAALNGLNFLTGCFLLPESHK 186
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 95.8 bits (238), Expect = 8e-25 Identities = 60/279 (21%), Positives = 112/279 (40%), Gaps = 39/279 (13%) Query: 84 QQPQRVVVLDSGEIDQVLSLGVTPVGIASPKDAS---SQPAYLKDQLADVQTVGTTSELN 140 P R+V L+ ++ +L+LG+ P G+A + S+P V VG +E N Sbjct: 33 IDPNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSEPPLPDS----VIDVGLRTEPN 88 Query: 141 FEAIAALKPDLILGSKLRVDESYDQLSQIAPTVL-----SIRPGFPWKENFLFTADALGL 195 E + +KP ++ S S + L++IAP +P +++ AD L L Sbjct: 89 LELLTEMKPSFMVWS-AGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNL 147 Query: 196 EGKAVEVLNEYQTHVDAVRETI--DGSPEISLVRFM-PGRTRLYGNLSFIGVILKDLGLS 252 + A L +Y+ + +++ G+ + L + P ++G S IL + G+ Sbjct: 148 QSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYGIP 207 Query: 253 RP----------EIQNIDDLAVEISPENIADANGDWIFYSTYGKPEATEQDNILSNELWH 302 +ID LA + + + + + D +++ LW Sbjct: 208 NAWQGETNFWGSTAVSIDRLAAYKDVDVLC-----------FDHDNSKDMDALMATPLWQ 256 Query: 303 NLPAVQDGKALEVNDESWFMGLGPLGANEVLNDIENILG 341 +P V+ G+ V WF G L A + ++N +G Sbjct: 257 AMPFVRAGRFQRVPA-VWFYG-ATLSAMHFVRVLDNAIG 293
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 65.7 bits (160), Expect = 2e-14 Identities = 40/180 (22%), Positives = 75/180 (41%), Gaps = 20/180 (11%) Query: 53 NPQRVVVLEPLELDTAIALGITPVGAAVANNVTGIPAYLG----VDGIEPVGTVSEPNIE 108 +P R+V LE L ++ +ALGI P G A + ++ D + VG +EPN+E Sbjct: 34 DPNRIVALEWLPVELLLALGIVPYGVA---DTINYRLWVSEPPLPDSVIDVGLRTEPNLE 90 Query: 109 AIAALEPDLILGTDSRHAEIYDRLESIAPTVFMA-----THVDPWKDNVVFIGDALGKKQ 163 + ++P ++ + + + + L IAP + + ++ + D L + Sbjct: 91 LLTEMKPSFMVWS-AGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNLQS 149 Query: 164 ESEDLIQGFNDKCEEIKSEHDVEGKT----VNMIRPRDEQTMSLYGPTSFAGSSLECAGL 219 +E + + D +K G +I PR M ++GP S L+ G+ Sbjct: 150 AAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRH---MLVFGPNSLFQEILDEYGI 206
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.4 bits (66), Expect = 0.009 Identities = 9/33 (27%), Positives = 16/33 (48%) Query: 9 PPKAPTWLGWVLMIGGIIGLILSVIIMAEKLAI 41 + P + + +M +I ILSV+ E +A Sbjct: 53 VSRRPRLVAYFIMGFLVIAFILSVLGQVEIVAT 85
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 43.4 bits (102), Expect = 5e-07 Identities = 18/97 (18%), Positives = 39/97 (40%), Gaps = 5/97 (5%) Query: 102 VANLGSHREPDLEALAAAQPSLIINGQRFAQYYDDIVALNPDATVVELDPRDGE-PLDQE 160 V ++G EP+LE L +PS ++ + + + + P + DG+ PL Sbjct: 78 VIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGRG---FNFSDGKQPLA-M 133 Query: 161 LIRQAETLGEIFGEEEDAAKIVADFESALERAKTAYA 197 + + ++ + A +A +E + K + Sbjct: 134 ARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFV 170
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 28.3 bits (63), Expect = 0.029 Identities = 7/29 (24%), Positives = 17/29 (58%) Query: 46 LFSNGAVWMWMIAIVMVFLALLSFIMIPV 74 F ++ W++AI+++ L+ + +PV Sbjct: 4 FFIRRPIFAWVLAIILMMAGALAILQLPV 32
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 49.2 bits (117), Expect = 1e-09 Identities = 25/187 (13%), Positives = 63/187 (33%), Gaps = 12/187 (6%) Query: 1 MSGLRETKKAATRTALSRAAAEIALMEGPEAFTVAAIAAAAGVSPRTFHNYFPSREDALV 60 M+ + + TR + A + +G + ++ IA AAGV+ + +F + D Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 QFVVIRVQELTDQLYEFPTSVP--PRDAIEQLVINQLRDG--DDAMDSF-------SAMF 109 + + + + E+ P P + +++I+ L ++ Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 110 RIGEILENLDPIKCVIDKERLIAPLLEFMVERDKDLDKFDAATLIHLHAAAIATSLHTFY 169 +++ C ++ I L+ +E + I+ + + Sbjct: 121 GEMAVVQQAQRNLC-LESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWL 179 Query: 170 QSPEPRD 176 +P+ D Sbjct: 180 FAPQSFD 186
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 50.6 bits (121), Expect = 2e-08 Identities = 34/165 (20%), Positives = 62/165 (37%), Gaps = 17/165 (10%) Query: 587 LIVLVLAFLVLLLVFRSIWVPLIAALGFGLSVLATFGATVAIFQEGAFGIIDDPQPLLSF 646 ++L FLV+ L +++ LI + + +L TF AFG ++ Sbjct: 345 FEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILA------AFGYS------INT 392 Query: 647 LPIMLIGLVFGLAMDYQIFLVTRMREGFTKGKTAG-NATSNGFKHGARVVTAAALIMVSV 705 L + + L GL +D I +V + + K AT + A+++ +V Sbjct: 393 LTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAV 452 Query: 706 F---AAFIAQDMAFIKTMGFALAVAVFFDAFVVRMMIIPATMFLL 747 F A F A + + A+ V +++ PA L Sbjct: 453 FIPMAFFGGSTGAIYRQFSITIVSAMALSVLVA-LILTPALCATL 496 Score = 47.5 bits (113), Expect = 2e-07 Identities = 43/248 (17%), Positives = 93/248 (37%), Gaps = 27/248 (10%) Query: 144 AADIESISPLSADETTGI-ISMTFDADSAMDVSAEDREKVTNILDEYNDG-DLTVVYNGN 201 + I+ ++ G+ I + A+ A+D + + K+ + + G + Y+ Sbjct: 272 GENYNVIARINGKPAAGLGIKLATGAN-ALDTAKAIKAKLAELQPFFPQGMKVLYPYDTT 330 Query: 202 VFGAAATSLDMTSELIGLLVAAVVLIVTFGSFIAAGMPLISAIIGVGIGIMGIQLATAFT 261 F + + + +++ +V+ + + A +P I+ + + + AF Sbjct: 331 PFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILA---AFG 387 Query: 262 ESVNDMTPTLASMIGLAVGI--DYALFIVSRFRNELISQTGANDLEPKELAERLRTMPLA 319 S+N +T + M+ LA+G+ D A+ +V ++ + P Sbjct: 388 YSINTLT--MFGMV-LAIGLLVDDAIVVVENVERVMMED---------------KLPPKE 429 Query: 320 ARAHAMGMAVGTAGSAVVFAGTTVLIALVALSIINIPFLTVMAIAAAITVAIAVLVALSF 379 A +M + A + + V I + +I +A++VLVAL Sbjct: 430 ATEKSMS-QIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALIL 488 Query: 380 LPALLGLL 387 PAL L Sbjct: 489 TPALCATL 496
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 30.1 bits (67), Expect = 0.022 Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 8/65 (12%) Query: 104 IPKPN--PGSSNGGNGG-----NPDGGPDGGDSGDDDSGDD-DPDPEPDKPEDGKPDGDK 155 IP+P+ PGS+ N +P P + +++ G +P+P+PD D PD D Sbjct: 310 IPRPDLTPGSAEAPNAQPLPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTDG 369 Query: 156 PRGPR 160 G R Sbjct: 370 QPGTR 374
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 181 bits (461), Expect = 9e-52 Identities = 113/481 (23%), Positives = 202/481 (41%), Gaps = 72/481 (14%) Query: 48 RRRTFAVIAHPDAGKSTLTEALALHAHIISEAGATHGKAGRKATVSDWMEMEKDRGISIA 107 + V+AH DAGK+TLTE+L ++ I+E G+ G T +D +E+ RGI+I Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVD--KG--TTRTDNTLLERQRGITIQ 57 Query: 108 SSALQFEYAPEGHEGEPFMINLVDTPGHADFSEDTYRVLMAVDAAVMLIDAAKGLEPQTL 167 + F++ E + +N++DTPGH DF + YR L +D A++LI A G++ QT Sbjct: 58 TGITSFQW--ENTK-----VNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTR 110 Query: 168 QLFRVCKARGLPIITVINKWDRVGRTPLELVDEIVKEIELQPTPLFWPVGEAGDFRGLAR 227 LF + G+P I INK D+ G + ++I+ + + + + + Sbjct: 111 ILFHALRKMGIPTIFFINKIDQNGIDL----STVYQDIKEKLSAEIVIKQKVELYPNMCV 166 Query: 228 INNDGEAEEYIHFTRTAGGSTIAPEDFYTPEEAIEREGDVWENATEEAELLAADGAVHDQ 287 N E+E++ + IE D+ E L A + + Sbjct: 167 TNFT-ESEQW--------------------DTVIEGNDDLLEKYMSGKSLEALELEQEES 205 Query: 288 ELFLNCTTSPLIFASAMLNFGVHQILDTLCQLAPSPAGRDADPKALEAATSAMDDHRDTT 347 F NC+ P+ SA N G+ +++ + S R Sbjct: 206 IRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSSTHRGQSE----------------- 248 Query: 348 DDFSGVVFKVQAGMDKNHRDTLAFMRVVSGEFDRGMQVTHSQSGRSFSTKYALTVFGRTR 407 G VFK++ +K R LA++R+ SG V S+ + T+ ++ G Sbjct: 249 --LCGKVFKIEYS-EKRQR--LAYIRLYSGVLHLRDSVRISEKEKIKITEMYTSINGE-L 302 Query: 408 STVETAFPGDIVGLVNAGA---LAPGDTIF--EGRKIQYPPMPKFAPEHFRILRAKSLGK 462 ++ A+ G+IV L N GDT + +I+ P P + + Sbjct: 303 CKIDKAYSGEIVILQNEFLKLNSVLGDTKLLPQRERIENPL-----PLLQTTVEPSKPQQ 357 Query: 463 YKQFRKALEQL-DSEGVVQILKNDLRGDANPVMAAVGPMQFEVMQARMEVEYNVETVADP 521 + AL ++ DS+ +++ + + +++ +G +Q EV A ++ +Y+VE Sbjct: 358 REMLLDALLEISDSDPLLRYYVDSATHEI--ILSFLGKVQMEVTCALLQEKYHVEIEIKE 415 Query: 522 I 522 Sbjct: 416 P 416
>PF01540#Adhesin lipoprotein Length = 475 Score = 30.9 bits (69), Expect = 0.011 Identities = 17/54 (31%), Positives = 30/54 (55%), Gaps = 4/54 (7%) Query: 398 DDPLMKATARKKGSRRLKQSNILVRDLKVLFGKSPEKPLKVETRAENLAENSEA 451 DD L + ++K LKQ+N L +LK K+P+ +ET + +AE +++ Sbjct: 29 DDKLAEKNGKEKADAALKQANALAEELK----KNPDYSKILETLNKEIAEATKS 78
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 29.3 bits (65), Expect = 0.005 Identities = 19/99 (19%), Positives = 33/99 (33%), Gaps = 1/99 (1%) Query: 27 EDTTEETSTTSSSTTSSSSSSSSSSTAATSEESSAVEEPAVEAPVEEAPVEAPVEQAPVV 86 T E+ ++ TT+ + + + + + E + +E E A V Sbjct: 1048 SKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVE 1107 Query: 87 EQAPVEQAPAPVQEAPAPVEQAPAPVQEAPAADAPPALP 125 ++ + QE P Q P QE P A P Sbjct: 1108 KEEKAKVETEKTQEVPKVTSQVS-PKQEQSETVQPQAEP 1145
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 37.9 bits (88), Expect = 3e-05 Identities = 18/61 (29%), Positives = 27/61 (44%), Gaps = 10/61 (16%) Query: 30 KIVVVKYGGNAMVDDDLKAAFAADMVFLRTV----------GAKPVVVHGGGPQISEMLN 79 K VV+ GGNA+ K ++ M +R G + V+ HG GPQ+ +L Sbjct: 3 KRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSLLL 62 Query: 80 R 80 Sbjct: 63 H 63
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 178 bits (454), Expect = 2e-60 Identities = 45/151 (29%), Positives = 83/151 (54%), Gaps = 6/151 (3%) Query: 16 VTRTARQALILQILDKQKVTSQVQLSELLLDEGIDITQATLSRDLDELGARKVRPDGGRA 75 + + R I +I+ ++ +Q +L ++L +G ++TQAT+SRD+ EL KV + G Sbjct: 1 MNKGQRHIKIREIITANEIETQDELVDILKKDGYNVTQATVSRDIKELHLVKVPTNNGSY 60 Query: 76 YYAVGPVDSIAREDLRGPSEKLRRMLDELLVSTDHSGNIAMLRTPPGAAQYLASFIDRVG 135 Y S+ + P KL+R L + V D + ++ +L+T PG AQ + + +D + Sbjct: 61 KY------SLPADQRFNPLSKLKRSLMDAFVKIDSASHLIVLKTMPGNAQAIGALMDNLD 114 Query: 136 LKEVVGTIAGDDTVFVLARDPLTGKELGELL 166 +E++GTI GDDT+ ++ R K + + + Sbjct: 115 WEEIMGTICGDDTILIICRTHDDTKVVQKKI 145
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 103 bits (259), Expect = 7e-29 Identities = 62/236 (26%), Positives = 104/236 (44%), Gaps = 9/236 (3%) Query: 5 MNGQTAIVTGAAGGIGSAVVTKFIESGVNVVAVDLYQQALDVLIEEVGTSGGEIVPLAGD 64 + G+ A +TGAA GIG AV G ++ AVD + L+ ++ + D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 65 VTDPLLAIRAVELSRSKFGGLDILVNNAGMGSDMVPLWEIDLETWRRDIEVNLTSQFMML 124 V D + G +DILVN AG+ + + E W VN T F Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGV-LRPGLIHSLSDEEWEATFSVNSTGVFNAS 124 Query: 125 KAVIPGMIEQGYGRIVNTASAAGMEGHALSSPYAAAKGGVIAMTKAVGKELATKGVLVNA 184 ++V M+++ G IV S + YA++K + TK +G ELA + N Sbjct: 125 RSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184 Query: 185 IAPALIGSGMLDQPWFDEKTKKQLLE--------RIPMGRVGEPTEVAEMITFLAS 232 ++P + M W DE +Q+++ IP+ ++ +P+++A+ + FL S Sbjct: 185 VSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVS 240
>PF06580#Sensor histidine kinase Length = 349 Score = 37.5 bits (87), Expect = 1e-04 Identities = 17/106 (16%), Positives = 35/106 (33%), Gaps = 26/106 (24%) Query: 385 LVANGLNHG----GPDAEVSIEINTDGQNVKILVADNGVGMSEEDAQHIFERFYRADSSR 440 LV NG+ HG ++ ++ D V + V + G + + Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE------------- 309 Query: 441 SRASGGSGLGLAITK---SLVEGHGGTVTVDSVQGEGTVFTITLPA 483 +G GL + ++ G + + QG+ + +P Sbjct: 310 -----STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNA-MVLIPG 349
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 102 bits (256), Expect = 3e-27 Identities = 34/118 (28%), Positives = 56/118 (47%) Query: 14 IRVLVVDDEPNIVELLTVSLKFQGFAVMTANDGNEALKIAREFRPDAYILDVMMPGMDGF 73 +LV DD+ I +L +L G+ V ++ + D + DV+MP + F Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 74 ELLTKLRSEGLDSPVLYLTAKDAVEHRIHGLTIGADDYVTKPFSLEEVITRLRVILRR 131 +LL +++ D PVL ++A++ I GA DY+ KPF L E+I + L Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 150 bits (379), Expect = 3e-42 Identities = 82/398 (20%), Positives = 158/398 (39%), Gaps = 16/398 (4%) Query: 28 FLIGVDNSILYTALPLLREQLAATETQALWIINAYPLLMAGLLLGTGTLGDKIGHRRMFL 87 F ++ +L +LP + W+ A+ L + G L D++G +R+ L Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 88 MGLSIFGIASLGAAFAPTAWA-LVAARAFLGIGAATMMPATLALIRITFEDERERNTAIG 146 G+ I S+ + ++ L+ AR G GAA PA + ++ + + R A G Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAA-AFPALVMVVVARYIPKENRGKAFG 142 Query: 147 IWGSVAILGAAAGPIIGGALLEFFWWGSVFLINVPVAVIALIATLFVAPANIANPSKHWD 206 + GS+ +G GP IGG + + W +L+ +P+ I + L H+D Sbjct: 143 LIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKEVRIKGHFD 200 Query: 207 FLSSFYALLTLAGLIITIKESVNTARHMPLLLGAVIMLIIGAVLFSSRQKKIEEPLLDLS 266 ++ ++ I+ + + +I+ ++ ++F +K+ +P +D Sbjct: 201 IK----GIILMSVGIVFFMLFTTSY-----SISFLIVSVLSFLIFVKHIRKVTDPFVDPG 251 Query: 267 LFRNRLFLGGVVAAGMAMFTVSGLEMTTSQRFQLSVGFTPLEAGF-LMIPAALGSFPMSI 325 L +N F+ GV+ G+ TV+G + + E G ++ P + Sbjct: 252 LGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGY 311 Query: 326 IGGANLHRWGFKPLISGGFFATAVGIALCIWGATHTDGLPFFIAGLFFMGAGAGSVMSVS 385 IGG + R G +++ G +V F + F+ G +V Sbjct: 312 IGGILVDRRGPLYVLNIGVTFLSVS--FLTASFLLETTSWFMTIIIVFVLGGLSFTKTVI 369 Query: 386 STAIIGSAPVRKAGMASSIEEVSYEFGTLLSVAILGSL 423 ST + S ++AG S+ + +AI+G L Sbjct: 370 STIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGL 407
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 50.0 bits (119), Expect = 4e-10 Identities = 25/122 (20%), Positives = 50/122 (40%), Gaps = 2/122 (1%) Query: 2 RTSKKEMILRTAIDYIGEHSLETLSYDSLAEATGLSKSGLIYHFPSRHALLLGMHELLAD 61 ++ IL A+ + + + S +A+A G+++ + +HF + L + EL Sbjct: 9 AQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSES 68 Query: 62 DWDKELRDIT-RDPEDPLERLRAVVV-TLAENVSRPELLLLIDAPSHPDFLNAWRTVNHQ 119 + + + + P DPL LR +++ L V+ LL++ H V Q Sbjct: 69 NIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQ 128 Query: 120 WI 121 Sbjct: 129 AQ 130
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.4 bits (92), Expect = 2e-05 Identities = 75/380 (19%), Positives = 128/380 (33%), Gaps = 44/380 (11%) Query: 57 NATSLYSMAVAIAGVIVAVVAPVMGRRSDIKGTRRRSLRMWTLVTVFLMFCLFTVKNTDP 116 + T+ Y + +A+ ++ APV+G SD G RR + + +L + + + Sbjct: 40 DVTAHYGILLALYALMQFACAPVLGALSDRFG--RRPVLLVSLAGAAVDYAIMATAPFLW 97 Query: 117 TFFWFGVAIMAIANITFEFAEVQYYAQLSQISTRENVGRVSGFGWSMGYFGGIVLLLVCY 176 + G + I T A Y A ++ R FG+ FG Sbjct: 98 VLY-IGRIVAGITGATGAVA-GAYIADITDGDER-----ARHFGFMSACFG--------- 141 Query: 177 LGFVAGDGDTRGFLNLPIEDGMNIRLVAVLAAVWFLVSAIPALLRVPEIEPQVAAEDHPK 236 G VAG G + G + AA ++ + +PE E P Sbjct: 142 FGMVAGPV-LGGLMG-----GFSPHAPFFAAAALNGLNFLTGCFLLPESHK---GERRPL 192 Query: 237 GLIAAYKDLFGQIAELWKQDRNSVYFLIAAAVFRDGLAGVF-TFGAILAVSVYGLSAGDV 295 A + W + V L+A + V I + A + Sbjct: 193 RREA--LNPLASFR--WARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTI 248 Query: 296 LLFGVAANVVSALGALLGGFLDDRV----GPKPIILISLTIMIIDATVLFFVEGPTNFWI 351 G++ L +L + V G + +++ MI D T + T W+ Sbjct: 249 ---GISLAAFGILHSLAQAMITGPVAARLGERRALMLG---MIADGTGYILLAFATRGWM 302 Query: 352 F--GLILCAFVGPAQSASRSYLTRLSPDGQEGQLFGLYATTGRAVSWMAPSLFGVFVGLT 409 ++L A G A ++ L+R + ++GQL G A S + P LF + Sbjct: 303 AFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAAS 362 Query: 410 GDDRTGILAIALILLFGIVL 429 G IA L+ + L Sbjct: 363 ITTWNGWAWIAGAALYLLCL 382
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 43.4 bits (102), Expect = 2e-06 Identities = 25/82 (30%), Positives = 33/82 (40%), Gaps = 4/82 (4%) Query: 138 VHAVPEPARVPEQVFEQVVAP---EPVLDPEPAPEPVAKPEPMAEPAPELVRKPAHQAEP 194 VH V E + + +VAP EP +P PEPV +PEP EP PE K A Sbjct: 37 VHQVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPE-PPKEAPVVIE 95 Query: 195 SVAEIPETPEPDPTPAPRRRRQ 216 P+ + +R Sbjct: 96 KPKPKPKPKPKPVKKVEQPKRD 117 Score = 43.0 bits (101), Expect = 2e-06 Identities = 21/97 (21%), Positives = 33/97 (34%), Gaps = 6/97 (6%) Query: 133 PELEPVHAV-PEPARVPEQVFEQVVAPEPVLDPEPAPEPVAKPEPMAEPAPELVRKPAHQ 191 +LEP AV P P V E E PEP + E + V +P Sbjct: 58 ADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRD 117 Query: 192 AEPSVAEIPETPEPDPTPAPRRRRQNTGSHRSASAEA 228 +P E+ P R + + +A+++ Sbjct: 118 VKP-----VESRPASPFENTAPARPTSSTATAATSKP 149 Score = 40.0 bits (93), Expect = 2e-05 Identities = 23/95 (24%), Positives = 35/95 (36%), Gaps = 1/95 (1%) Query: 122 YAEVIEEPEHEPELEPVHAVPEPARVPEQVFEQVVAPEPVLDPEPAPEPVAKPEPMAEPA 181 Y V + E +P+ E PEPV++PEP PEP+ +P A Sbjct: 34 YTSVHQVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVV 93 Query: 182 PELVRKPAHQAEPSVAEIPETPEPDPTPAPRRRRQ 216 E + V ++ + P+ D P R Sbjct: 94 IEKPKPKPKPKPKPVKKVEQ-PKRDVKPVESRPAS 127 Score = 38.0 bits (88), Expect = 9e-05 Identities = 18/95 (18%), Positives = 27/95 (28%), Gaps = 3/95 (3%) Query: 121 HYAEVIEEPEHEPELEPVHAVPEPARVPEQVFEQVVAPEPVLDPEPAPEPVAKPEPMAEP 180 + EP EPE EP +PEP + V E+ + V +P+ +P Sbjct: 64 QAVQPPPEPVVEPEPEPE-PIPEPPKEAPVVIEKPKPKPKP--KPKPVKKVEQPKRDVKP 120 Query: 181 APELVRKPAHQAEPSVAEIPETPEPDPTPAPRRRR 215 P P+ P Sbjct: 121 VESRPASPFENTAPARPTSSTATAATSKPVTSVAS 155
>cloacin#Cloacin signature. Length = 551 Score = 31.2 bits (70), Expect = 0.019 Identities = 15/37 (40%), Positives = 20/37 (54%) Query: 856 GSGSGGGFGSSNGGGFGSGSGSNDTNGGFGSSGGFGA 892 G GSG G G G G+G G+ ++ GG G+ G A Sbjct: 47 GGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSA 83
>cloacin#Cloacin signature. Length = 551 Score = 35.1 bits (80), Expect = 2e-04 Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 3/67 (4%) Query: 18 GGFSGGQSGFGGGSQNSGFGGSSG---GFSGGSSNGSFGGSTGGFTPAGSTSNPSGFSTP 74 G G G G S+N+ +GG SG + GGS +G+ GG+ +G+ N S + P Sbjct: 28 GVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAP 87 Query: 75 RATESPA 81 A PA Sbjct: 88 VAFGFPA 94 Score = 32.8 bits (74), Expect = 8e-04 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%) Query: 10 GGTFGSSSG-GFSGGQSGFGGGSQNSGFGGSSGGFSGGSSNGSFGGSTGGFTPAGSTSNP 68 G G+S G G+S + +GGGS + G G G NG+ GG +G + + P Sbjct: 28 GVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAP 87 Query: 69 SGFSTPRATESPAPG 83 F P A +P G Sbjct: 88 VAFGFP-ALSTPGAG 101 Score = 32.4 bits (73), Expect = 0.001 Identities = 27/94 (28%), Positives = 33/94 (35%), Gaps = 2/94 (2%) Query: 16 SSGGFSGGQSGFGGGSQNSGFGGSSGGFSGGSSNGSFGGSTGGFTPAGSTSNPSGFSTPR 75 S G G +G S N G + G GG+S+GS S GS S Sbjct: 2 SGGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSG 61 Query: 76 ATESPAPGRSSGRKRAGGRLQS--APTEWILPGL 107 G S G GG L + AP + P L Sbjct: 62 HGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPAL 95 Score = 30.8 bits (69), Expect = 0.003 Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 1/47 (2%) Query: 8 PPGGTFGSSSGGFSGGQSGFGGGSQNSGFG-GSSGGFSGGSSNGSFG 53 P GG GS G G GGG+ NSG G G+ G S ++ +FG Sbjct: 45 PWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFG 91
>PF07201#Hypersensitivity response secretion protein HrpJ Length = 293 Score = 31.7 bits (72), Expect = 0.004 Identities = 8/44 (18%), Positives = 17/44 (38%) Query: 217 LEGAVHSGQYGGAAPDAVAALVRVLDTLRDEHGRTVIDGVNTTA 260 L G + + + + L ++ +E G T++ G T Sbjct: 139 LCGLRDALKGRPELAHLSHLVEQALVSMAEEQGETIVLGARITP 182
>SECYTRNLCASE#Preprotein translocase SecY subunit signature. Length = 437 Score = 29.0 bits (65), Expect = 0.008 Identities = 18/93 (19%), Positives = 39/93 (41%), Gaps = 13/93 (13%) Query: 4 NLFLLLAAGTLISAGVYLLLDRAMTKMIMGLML----IGNGANLLILVAGGSAGSPPILG 59 ++F + ++AG ++ M +G ++ IGNG ++L+ +A P L Sbjct: 156 SIFTTITMVICMTAGTCVV-------MWLGELITDRGIGNGMSILMF-ISIAATFPSALW 207 Query: 60 RESEIYGDKTADPLAQAMILTAIVISMALTAFM 92 + G + ++ +I +AL F+ Sbjct: 208 AIKK-QGTLAGGWIEFGTVIAVGLIMVALVVFV 239
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 28.6 bits (64), Expect = 0.024 Identities = 10/38 (26%), Positives = 18/38 (47%), Gaps = 3/38 (7%) Query: 25 PAFRVLRE--KRTLDFRAPITVITGENGVGKSTLLEAI 60 A + + R + + +ITGE+G GK + A+ Sbjct: 144 AAMQEIYRVLARLMQTDLTL-MITGESGTGKELVARAL 180
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 37.5 bits (87), Expect = 9e-05 Identities = 36/143 (25%), Positives = 56/143 (39%), Gaps = 15/143 (10%) Query: 255 GFTISLHVAGMYALSPVFGLLTDKLGRNVTIYSGFAMIAASAAFLVIWPEPQWAMITSMI 314 G ++L+ +A +PV G L+D+ GR + A A A + P W + I Sbjct: 46 GILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPF-LWVLYIGRI 104 Query: 315 LLGL-GWNSALVGSSTLLVDATPIHHRTYAQGRSDLTMNLAGASGGLIAGPLIA--MGG- 370 + G+ G A+ G+ + D T R G A G++AGP++ MGG Sbjct: 105 VAGITGATGAVAGA--YIADITDGDERARHFGFMS-----ACFGFGMVAGPVLGGLMGGF 157 Query: 371 ---MPLLAGVVLAVVALQTVLSF 390 P A L + T Sbjct: 158 SPHAPFFAAAALNGLNFLTGCFL 180
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 32.3 bits (73), Expect = 0.004 Identities = 22/146 (15%), Positives = 38/146 (26%), Gaps = 10/146 (6%) Query: 99 VVPAVPVVPTPSAPGSAVPAPSAPGSAIPTP--GSAIPAPGVSAPGANVPSVSAPGASIP 156 V V +P P+ P S A + P P P V P P + Sbjct: 36 SVHQVIELPAPAQPISVTMVAPA---DLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPV 92 Query: 157 SIPAPGSTTPPAPGISAPGSALPTPGSTPPAPGIPAPGIPAPGIPTPGSALPVPGTPGAT 216 I P P P P + + P T + Sbjct: 93 VIEKP--KPKPKP---KPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATS 147 Query: 217 GAPGAPSTPPQSAAPAKPVFQDAEKR 242 + ++ P++ + +P + + Sbjct: 148 KPVTSVASGPRALSRNQPQYPARAQA 173 Score = 30.3 bits (68), Expect = 0.018 Identities = 22/120 (18%), Positives = 26/120 (21%), Gaps = 4/120 (3%) Query: 42 PVSANPPAPGNAIPAPGGSVPAPGASVPAPGASTPSIPTAPGGAVPAPGGAVPVPGGVVP 101 P+S AP + P P P P P V P P Sbjct: 49 PISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEK----PKPKPKPK 104 Query: 102 AVPVVPTPSAPGSAVPAPSAPGSAIPTPGSAIPAPGVSAPGANVPSVSAPGASIPSIPAP 161 PV P S P S A P + + P S Sbjct: 105 PKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQ 164 Score = 29.9 bits (67), Expect = 0.023 Identities = 24/115 (20%), Positives = 34/115 (29%), Gaps = 5/115 (4%) Query: 27 AIPAPKSTEQEAAIPPVSANPPAPGNAIPAPG-GSVPAPGASVPAPGASTPSIPTAPGGA 85 +PAP + P PP P P P P P + I Sbjct: 42 ELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKP 101 Query: 86 VPAPGGAVPVPGGVVPAVPVVPTPSAP----GSAVPAPSAPGSAIPTPGSAIPAP 136 P P V PV P++P A P S +A P +++ + Sbjct: 102 KPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASG 156 Score = 28.8 bits (64), Expect = 0.046 Identities = 19/113 (16%), Positives = 26/113 (23%) Query: 76 PSIPTAPGGAVPAPGGAVPVPGGVVPAVPVVPTPSAPGSAVPAPSAPGSAIPTPGSAIPA 135 P+ + AP P P PVV P P I P Sbjct: 44 PAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKP 103 Query: 136 PGVSAPGANVPSVSAPGASIPSIPAPGSTTPPAPGISAPGSALPTPGSTPPAP 188 P +T P P S +A P ++ + Sbjct: 104 KPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASG 156
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.9 bits (64), Expect = 0.036 Identities = 9/20 (45%), Positives = 12/20 (60%) Query: 224 VLWLQGPNGSGKSTLLRGLA 243 + L+G G GKSTL+ L Sbjct: 598 SVVLEGTGGIGKSTLINTLV 617
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 125 bits (315), Expect = 3e-37 Identities = 85/249 (34%), Positives = 116/249 (46%), Gaps = 20/249 (8%) Query: 9 VALVTGAGRGIGAAIARALSDLDYVVVVTDAVERRAESVASSLGA-----DSAILDVTDE 63 +A +TGA +GIG A+AR L+ + D + E V SSL A ++ DV D Sbjct: 10 IAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDS 69 Query: 64 RQWKAVVAATERRHGGVDVLVNNAGVGFAAALDRTSREKWDGVLATNLTGPFLGCKTVAP 123 + A ER G +D+LVN AGV + S E+W+ + N TG F ++V+ Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSK 129 Query: 124 VMKRGGGGVIVNVSSIDAIRGREGLHAYAASKAGLRGLGQSLAVELAADGIRVNTVLPGL 183 M G IV V S A R + AYA+SKA + L +ELA IR N V PG Sbjct: 130 YMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGS 189 Query: 184 VPTSM----------TSRVDPGSFD-----IPLGRAAQPDEIAQVVAFLASTGASYVAGA 228 T M +V GS + IPL + A+P +IA V FL S A ++ Sbjct: 190 TETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITMH 249 Query: 229 EVVVDGALT 237 + VDG T Sbjct: 250 NLCVDGGAT 258
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 84.2 bits (208), Expect = 6e-20 Identities = 58/253 (22%), Positives = 111/253 (43%), Gaps = 14/253 (5%) Query: 80 FNTTAANASWIITVTLLVGAVATPVMGRLADMYGKKKMMLISLVPFVLGSVICAVSADLI 139 FN A+ +W+ T +L ++ T V G+L+D G K+++L ++ GSVI V Sbjct: 44 FNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF 103 Query: 140 PMII-GRGFQGLGSGLIP-LGISLMHDLLPREKAGSAIALMSSSMGIGGALGLPLAAAIA 197 ++I R QG G+ P L + ++ +P+E G A L+ S + +G +G + IA Sbjct: 104 SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIA 163 Query: 198 QFASWRVLFWFTALVALTVGAVIWKAIPARPRIVRSGGFDYFGTLGLAMGIIALLLAVSK 257 + W L + +TV ++ K + R G FD G + +++GI+ +L + Sbjct: 164 HYIHWSYLLLIPMITIITVPFLM-KLLKKEVR--IKGHFDIKGIILMSVGIVFFMLFTTS 220 Query: 258 GSEWGWRSALTIGLFVAALVILVSWGWFETRQKSPLIDLRTTIRATVLMTNIASILIGFT 317 S + + + I + P +D ++ + +I T Sbjct: 221 YS-ISFLIVSVLSFLIFVKHIR--------KVTDPFVDPGLGKNIPFMIGVLCGGIIFGT 271 Query: 318 MYGMNLILPQVMQ 330 + G ++P +M+ Sbjct: 272 VAGFVSMVPYMMK 284
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 53.7 bits (129), Expect = 9e-11 Identities = 31/125 (24%), Positives = 49/125 (39%), Gaps = 10/125 (8%) Query: 2 IRVLLADDHEIVRLGLRAVLESAEDIEVVGEVSTAEGAVQAAQEGGIDVILMDLRFGPGV 61 +L+ADD +R L L +V S A + G D+++ D+ Sbjct: 4 ATILVADDDAAIRTVLNQALSR-AGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDE- 60 Query: 62 QGTQVSTGADATAAIKRNIDNPPKVLVVTNYDTDADILGAIEAGALGYLLKDAPPSELLA 121 D IK+ + P VLV++ +T + A E GA YL K +EL+ Sbjct: 61 ------NAFDLLPRIKKARPDLP-VLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIG 113 Query: 122 AVRSA 126 + A Sbjct: 114 IIGRA 118
>PF06580#Sensor histidine kinase Length = 349 Score = 41.0 bits (96), Expect = 6e-06 Identities = 56/359 (15%), Positives = 126/359 (35%), Gaps = 56/359 (15%) Query: 66 LLFVWGFLYFYGSTKRVDLSHGMQ---LGWLFVLTL---------VWIFMVPIVPVSIYL 113 L +GF YGS K + + +G + + + M I+ + Sbjct: 24 TLTGFGFASLYGSPKLHSMIFNIAISLMGLVLTHAYRSFIKRQGWLKLNMGQIILRVLPA 83 Query: 114 LFPLFFLYLQVMPDVRGIIAILGATAIAIASQYSVGLTFGGVMGPVVSAIVTVAIDYAFR 173 + ++ + ++A + +A ++ + F V+ + +++ + Sbjct: 84 CVVIGMVWFVANTSIWRLLAFINTKPVAFTLPLALSIIFNVVVVTFMWSLLYFGWHFF-- 141 Query: 174 TLWRVNNEKQELIDQLIETRSQLAVTERNAGIAAERQRI-AHEIHDTVAQGLSSIQMLLH 232 N KQ IDQ ++A + A + A + +I H + + L++I+ L Sbjct: 142 -----KNYKQAEIDQW-----KMASMAQEAQLMALKAQINPHFMFNA----LNNIRAL-- 185 Query: 233 VSEQEILVAEMEEKPKEAIVKKMRLARQTASDNLSEARAMIAAL-QPAALSKTSLEAALH 291 + E K +E + L R +L + A +L + + L+ A Sbjct: 186 -------ILEDPTKAREMLTSLSELMRY----SLRYSNARQVSLADELTVVDSYLQLASI 234 Query: 292 RVTEPLLGINFVISIDGDVRQLPMKTEATLLRIAQGAIGNVAKHSEAKNC-HVTLTYEDT 350 + + L F I+ + + + + + + I + + T ++ Sbjct: 235 QFEDRL---QFENQINPAIMDVQVPP-MLVQTLVENGIKHGIAQLPQGGKILLKGTKDNG 290 Query: 351 EVRLDVVDDGVGFEPSEVSSTPAGLGHIGLTALQQRAMELHGE---VIVESAYGQGTAV 406 V L+V + G + ST GL +++R L+G + + G+ A+ Sbjct: 291 TVTLEVENTGSLALKNTKEST-----GTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAM 344
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 95.8 bits (238), Expect = 2e-23 Identities = 59/274 (21%), Positives = 104/274 (37%), Gaps = 71/274 (25%) Query: 4 ILIYPVSGVMKLWHLLLHNVAGLDDSLAWFFSLFGLVITIRAIIAPFTWQMYKSGRTAAH 63 + P+ ++K H + N W FS+ + +R I+ P T Y S Sbjct: 335 FISQPLFKLLKWIHSFVGN---------WGFSIIIITFIVRGIMYPLTKAQYTSMAKMRM 385 Query: 64 IRPHRAALREEYKGKYDEASIRELQKRQNDLNKEYGINPLAGCVPGLIQIPIVLGLYWAL 123 ++P A+RE + + + L K +NPL GC P LIQ+PI L LY+ L Sbjct: 386 LQPKIQAMRERLGDDK-----QRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYYML 440 Query: 124 LRMARPEGGLENPVFQSIGFLTPEEVESFLAGRVSNVPLPAYVSMPTEQLEYLSTTQAEV 183 + S P ++ + Q Y Sbjct: 441 M-------------------------GSVEL---RQAPFALWIHDLSAQDPY-------- 464 Query: 184 LNFVLPLFITAAILTAINMAMSMYRSFQTNDYASGFSNGML-KFMIVMSILAPIFPLSLG 242 ++LP+ M ++M+ F + ++ M K M M ++ +F L Sbjct: 465 --YILPIL----------MGVTMF--FIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLW-- 508 Query: 243 LTGPFPTAIALYWVSNNLWTLLQTIIMMVILERK 276 FP+ + LY++ +NL T++Q ++ LE++ Sbjct: 509 ----FPSGLVLYYIVSNLVTIIQQQLIYRGLEKR 538
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 64.3 bits (156), Expect = 7e-15 Identities = 27/146 (18%), Positives = 48/146 (32%), Gaps = 8/146 (5%) Query: 15 ANRRRNRPSP-RQRLLDSATNLFTTEGIRVIGIDRILREADVAKASLYSLFGSKDALVIA 73 A + + RQ +LD A LF+ +G+ + I + A V + ++Y F K L Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 74 YLENLDQLWREAWRERTVGM-----KDPEDKIIAFFDQCIEEEPEKDFRGSHFQNAASEY 128 E + E E + +I + + EE + F Sbjct: 62 IWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVG 121 Query: 129 PRPETDSEKGIVAAVLEHREWCHKTL 154 ++ LE + +TL Sbjct: 122 EMAV--VQQAQRNLCLESYDRIEQTL 145
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 124 bits (313), Expect = 3e-39 Identities = 36/145 (24%), Positives = 67/145 (46%), Gaps = 2/145 (1%) Query: 13 DAKQLIDGLQERLTDYNDLHLILKHVHWNVTGPNFIAVHEMLDPQVDLVRGYADEVAERI 72 + + + L +L+++ L+ L HW V GP+F +HE + D D +AER+ Sbjct: 9 NQTLVENSLNTQLSNWFLLYSKLHRFHWYVKGPHFFTLHEKFEELYDHAAETVDTIAERL 68 Query: 73 STLGGAPVGTPEGHVADRTPLQYERNAGNAQAHLTDLNRVYTQVLTGVRESMASAGPV-D 131 +GG PV T + + + N +A + L Y Q+ + + + A D Sbjct: 69 LAIGGQPVATVKE-YTEHASITDGGNETSASEMVQALVNDYKQISSESKFVIGLAEENQD 127 Query: 132 PVTEDIYIGQAAELEKFQWFIRAHI 156 T D+++G E+EK W + +++ Sbjct: 128 NATADLFVGLIEEVEKQVWMLSSYL 152
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 50.7 bits (121), Expect = 2e-09 Identities = 45/219 (20%), Positives = 80/219 (36%), Gaps = 26/219 (11%) Query: 99 DISLEAIAAADPDLIISRLSDVEPIQEQLETIAPVL----PIGEQDTSTWQEDLRLVAQA 154 + +LE + P ++ P E L IAP G+Q + ++ L +A Sbjct: 86 EPNLELLTEMKPSFMVWSAG-YGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADL 144 Query: 155 TGTEQRAEELIADYDSRIKALSTQYADILANNTFAPLSFNGESFETR------PNRLLSV 208 + AE +A Y+ I+++ + PL + R PN L Sbjct: 145 LNLQSAAETHLAQYEDFIRSMKPR----FVKRGARPLLL-TTLIDPRHMLVFGPNSLFQE 199 Query: 209 VLRDLGATPSQAFEAAINGDATKYSPEQV----LTGFGDADGLIMLVNSPQTWQELQDNQ 264 +L + G A G+ + V L + D D L ++ + L Sbjct: 200 ILDEYG------IPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNSKDMDALMATP 253 Query: 265 LYQQLPAITEGHFVRSDKQTHEGGPLTALHALDVIEQLL 303 L+Q +P + G F R G L+A+H + V++ + Sbjct: 254 LWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVRVLDNAI 292
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 41.7 bits (98), Expect = 3e-06 Identities = 70/310 (22%), Positives = 105/310 (33%), Gaps = 20/310 (6%) Query: 21 FAAFVYVTFEMFAVGLIKP----MASDLGVSE---SSIGLLMTVYATVVAVVTIPAMLWV 73 V + +GLI P + DL S + G+L+ +YA + Sbjct: 8 IVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALS 67 Query: 74 SRFNKRTVFLITLAFLATGIVVQALTVNYGMLAIGRTIAALTHGVFWALVGPMAARMSPG 133 RF +R V L++LA A + A +L IGR +A +T A+ G A ++ G Sbjct: 68 DRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATG-AVAGAYIADITDG 126 Query: 134 HT-GRAVGVVSIGSTMALVVGSPLATWIGELIGWRP--ATWILGALTIAAVAVLIPTVPS 190 R G +S +V G L +G P A L L L+P Sbjct: 127 DERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHK 186 Query: 191 LPPLPDTESESKEKKSLPW-------GLISLVIFLLLAVTGVFAAYTYLGLIIAETAGDS 243 P S W + V F++ V V AA + + Sbjct: 187 GERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDAT 246 Query: 244 FVSIGLFAFGALGLIGVTVATRTVDQRMLRGSVHTTTLFVIAAILGQIAFGLEGTLAVVA 303 + I L AFG L + + T V R+ G L +IA G I + Sbjct: 247 TIGISLAAFGILHSLAQAMITGPVAARL--GERRALMLGMIADGTGYILLAFATRGWMAF 304 Query: 304 IFLAVTVFGG 313 + + GG Sbjct: 305 PIMVLLASGG 314
>THERMOLYSIN#Thermolysin metalloprotease (M4) family signature. Length = 544 Score = 30.0 bits (67), Expect = 0.016 Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 15/97 (15%) Query: 249 RGISGGINEAFTGADLF----IGVSGGN----IGEDALKLMAPQPILFTLANPTPEIDPE 300 + SG INEA +D+F + N IGED L ++++P DP+ Sbjct: 386 QNESGAINEAM--SDIFGTLVEFYANRNPDWEIGEDIYTPGVAGDALRSMSDPAKYGDPD 443 Query: 301 -LSQKYGAIVATG----RSDLPNQINNVLAFPGIFAG 332 S++Y G S + N+ +L+ G+ G Sbjct: 444 HYSKRYTGTQDNGGVHTNSGIINKAAYLLSQGGVHYG 480
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 63.5 bits (154), Expect = 5e-14 Identities = 58/228 (25%), Positives = 93/228 (40%), Gaps = 26/228 (11%) Query: 2 KSIFISGAANGIGKAVALKFVHEGWLVGAYDIA----EITYSHPNLRWGY-----LNVRQ 52 K FI+GAA GIG+AVA +G + A D E S + +VR Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 53 SESWDKALEDFATHTGGTIDVVDNNAGVIIEGPLQDAEEGSVDKLLAINVNGVTLGARAA 112 S + D+ G ID++ N AGV+ G + + + ++N GV +R+ Sbjct: 69 SAAIDEITARIEREMGP-IDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 113 HPYLARTPGAQLLNMSSASAVYGQPQIAVYSASKFYVAGLTEALNLEWRKDDIRVVDV-- 170 Y+ ++ + S A + +A Y++SK T+ L LE + +IR V Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 171 --------WPLWVKTDLVNGVKAKSLK--RLGVRIT----PEQVAQAV 204 W LW + V SL+ + G+ + P +A AV Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAV 235
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 32.9 bits (75), Expect = 0.003 Identities = 38/147 (25%), Positives = 54/147 (36%), Gaps = 10/147 (6%) Query: 89 GFVYMTSLVASFIADRV---LGSERTLFYSAIIVMLGHIALALIPGYTGLSIGLVLIGLG 145 F + SL + I V LG R L I G+I LA G +++ L Sbjct: 254 AFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFAT--RGWMAFPIMVLLA 311 Query: 146 SGGVKTAAQVVLGQLYSRTDTRRDAGF--SIFYMGVNLGGLFGPLITNALWGWGGFHWGF 203 SGG+ A L + SR G +L + GPL+ A++ W Sbjct: 312 SGGIGMPA---LQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASITTWNG 368 Query: 204 GIAAVGMALGLIQYVAMRKTTIGAAGH 230 G AL L+ A+R+ AG Sbjct: 369 WAWIAGAALYLLCLPALRRGLWSGAGQ 395
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 62.3 bits (151), Expect = 2e-14 Identities = 30/83 (36%), Positives = 43/83 (51%) Query: 7 KAAETRQRFIDVAHELFLEHGYGSTSMNQIAQAAGGSRANLYLHFRNKPDLMMAKMRELE 66 +A ETRQ +DVA LF + G STS+ +IA+AAG +R +Y HF++K DL E Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSE 67 Query: 67 PAVRTPVLKVFDLSEHTLESIFR 89 + L+ S+ R Sbjct: 68 SNIGELELEYQAKFPGDPLSVLR 90
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 32.9 bits (75), Expect = 0.003 Identities = 37/199 (18%), Positives = 76/199 (38%), Gaps = 15/199 (7%) Query: 24 RLGQISLVACLGGLLFGYDTGVANGAEGHMAQELGLNVLQLGVVISSLVFAAAFGALFAG 83 R QI + C+ + V N + +A + V ++ + + G G Sbjct: 11 RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYG 70 Query: 84 RISDAIGRRKAIITLSVLFFLGSILVVFSPAGELGQFYGPGFATLVTGRIMLGLAVGGAS 143 ++SD +G ++ ++ ++ GS+ G +G + F+ L+ R + G Sbjct: 71 KLSDQLGIKRLLLFGIIINCFGSV------IGFVGHSF---FSLLIMARFIQGAGAAAFP 121 Query: 144 TVVPVYLAELAPLEIRGSLTGRNELAIVTGQLLAFVINALIAVTLHGVIDGIWRIMFAVC 203 +V V +A P E RG G + G+ + I +IA +H W + + Sbjct: 122 ALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIH------WSYLLLIP 175 Query: 204 ALPAVALFLGMLRMPESPR 222 + + + M + + R Sbjct: 176 MITIITVPFLMKLLKKEVR 194
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 27.6 bits (61), Expect = 0.022 Identities = 19/97 (19%), Positives = 37/97 (38%), Gaps = 10/97 (10%) Query: 32 EVAAKADPVFEKEAWLSTTLL-------EYESCGFNIGYRNGTPALASVIFCERDAAPGA 84 V + P FE W T +YE ++ Y A + + E + G Sbjct: 21 VVFGRMIPAFENGVWTYTEERFSKPYFKQYEDDDMDVSYVEEEGKAAFLYYLE-NNCIGR 79 Query: 85 KALPTAPVSSDAAIISSLFIDEVFRGTGMESALLDAS 121 + + + A+I + + + +R G+ +ALL + Sbjct: 80 IKIRSN--WNGYALIEDIAVAKDYRKKGVGTALLHKA 114
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.8 bits (69), Expect = 0.011 Identities = 18/86 (20%), Positives = 25/86 (29%), Gaps = 8/86 (9%) Query: 59 TAAAPKRESTPAAPAPEAPAQAAPQHTEATKP-----EVVPEPAAPAPTQSAQQEAPQAQ 113 T E A Q P+ T P E V A PA + Q Sbjct: 1100 TKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQ 1159 Query: 114 PAQQSEFGASYLEIPIEQIRPNPQQP 139 + + E P ++ N +QP Sbjct: 1160 SQTNTT---ADTEQPAKETSSNVEQP 1182
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 127 bits (321), Expect = 3e-35 Identities = 61/296 (20%), Positives = 113/296 (38%), Gaps = 81/296 (27%) Query: 2 LNFIYWPISAILWFWHKAFSFVLSPDSGITWALSIMFLTFTVRMVLVKPMVNTMRSQRKM 61 L FI P+ +L + H W SI+ +TF VR ++ S KM Sbjct: 333 LWFISQPLFKLLKWIHSFVG---------NWGFSIIIITFIVRGIMYPLTKAQYTSMAKM 383 Query: 62 QDMAPKMQAIREKYKNDQQKMMEETRKLQKEVGVNPIAGCLPMLVQIPVFLGLFHVLRSF 121 + + PK+QA+RE+ +D+Q++ +E L K VNP+ GC P+L+Q+P+FL L+++L Sbjct: 384 RMLQPKIQAMRERLGDDKQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYYMLMG- 442 Query: 122 NRTGSGVGQLEMTVEQNANTPNYIFGVDEVQSFLRADLFGAPLSSYITMPADAFDAFLGL 181 +L AP + +I + ++ Sbjct: 443 ----------------------------------SVELRQAPFALWIHDLSAQDPYYI-- 466 Query: 182 DVSRLNIALVAAPMILIIVVATHMNARLSVNRQEARKAAGKQQAASSDQMAMQMQMMNKM 241 + +++ V ++S + M M + Sbjct: 467 -------------LPILMGVTMFFIQKMSPTTV------------TDPMQQKIMTFMPVI 501 Query: 242 MLWFMPATILFTGFIW-TIGLLVYMMSNNVWTFFQQRYIFAKMDAEEAAEEEEKRA 296 F F+W GL++Y + +N+ T QQ+ I+ ++ E+K++ Sbjct: 502 FTVF---------FLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS 548
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 29.0 bits (65), Expect = 0.005 Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 8/90 (8%) Query: 4 AQHKLNSSMQFRTVMRKGRRAGSKTVVVHLWDSAESLDGTEKQGEVASFGG-PRFGLVVS 62 AQ + + +F V + GS VV L D A G E +A G P GL + Sbjct: 236 AQTRFKNPEEFGKVTLRVNSDGS---VVRLKDVARVELGGENYNVIARINGKPAAGLGIK 292 Query: 63 KAVG-NAVVRHRTSRRLRHICASIVEKSPE 91 A G NA+ T++ ++ A + P+ Sbjct: 293 LATGANAL---DTAKAIKAKLAELQPFFPQ 319