>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 87.2 bits (216), Expect = 6e-22 Identities = 33/137 (24%), Positives = 59/137 (43%), Gaps = 1/137 (0%) Query: 8 PKILIVEDDERLARLTQEYLIRNGLEVGVETDGNRAIRRIISEQPDLVVLDVMLPGADGL 67 IL+ +DD + + + L R G +V + ++ R I + DLVV DV++P + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 68 TVCREVRPHY-HQPILMLTARTEDMDQVLGLEMGADDYVAKPVQPRVLLARIRALLRRTD 126 + ++ P+L+++A+ M + E GA DY+ KP L+ I L Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 127 KTVEDEVAQRIEFDDLV 143 + + LV Sbjct: 124 RRPSKLEDDSQDGMPLV 140
>PF06580#Sensor histidine kinase Length = 349 Score = 36.0 bits (83), Expect = 3e-04 Identities = 21/109 (19%), Positives = 42/109 (38%), Gaps = 24/109 (22%) Query: 399 VVQNLVGNAVRYC------DNKVRITGGIHSDGLAFVCVEDDGAGIPEQDRKRVFEAFAR 452 +VQ LV N +++ K+ + G +G + VE+ G+ + ++ Sbjct: 259 LVQTLVENGIKHGIAQLPQGGKILLKG-TKDNGTVTLEVENTGSLALKNTKE-------- 309 Query: 453 LDDSRTRASGGYGLGLSIVSRIAYWFGGEIKVDESPTLGGARFIMTWPA 501 S G GL ++ R+ +G E ++ S G ++ P Sbjct: 310 --------STGTGL-QNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIPG 349
>PF03309#Bvg accessory factor Length = 271 Score = 92.9 bits (231), Expect = 8e-25 Identities = 42/263 (15%), Positives = 96/263 (36%), Gaps = 34/263 (12%) Query: 4 LWLDIGNTRLKYWI----TENQQIIEH--AAELHLQSPADLLLGLIQHFKHQG--LHRIG 55 L +D+ NT + ++ ++++ + +L L + L Sbjct: 3 LAIDVRNTHTVVGLISGSGDHAKVVQQWRIRTEPEVTADELALTIDGLIGDDAERLTGAS 62 Query: 56 ISSVLDTENNQRIQQILKWLEI-PVVFAKVHSEYAGLQCGYEVPSQLGIDRWLQ-VLAVA 113 S + + ++ + ++ P V + G+ + P ++G DR + + A Sbjct: 63 GLSTVPSVLHEVRVMLEQYWPNVPHVLIEPGVR-TGIPLLVDNPKEVGADRIVNCLAAYH 121 Query: 114 QADENYCIIGCGTALTID-LTQGKQHLGGYILPNLYLQRDALIQNTK-----GIKIPDSA 167 + ++ G+++ +D ++ + LGG I P + + DA + + P S Sbjct: 122 KYGTAAIVVDFGSSICVDVVSAKGEFLGGAIAPGVQVSSDAAAARSAALRRVELTRPRSV 181 Query: 168 FDNLNPGNNTVDAVHHGILLGLISTIENIMQQS----------PKKLLLTGGDATLFAKF 217 G NTV+ + G + G ++ ++ + ++ TG A L Sbjct: 182 I-----GKNTVECMQAGAVFGFAGLVDGLVNRIRDDVDGFSGADVAVVATGHTAPLVLPD 236 Query: 218 LQKYEPVVETDLLLKGLQQYIAH 240 L + + L L GL + + Sbjct: 237 L-RTVEHYDRHLTLDGL-RLVFE 257
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 594 bits (1533), Expect = 0.0 Identities = 167/686 (24%), Positives = 280/686 (40%), Gaps = 78/686 (11%) Query: 9 RYRNIGISAHIDAGKTTTTERILFYTGVSHKIGEVHDGAATMDWMEQEQERGITITSAAT 68 + NIG+ AH+DAGKTT TE +L+ +G ++G V G D E++RGITI + T Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 69 TCFWSGMGNQFEQHRINVIDTPGHVDFTIEVERSMRVLDGACMVYCAVGGVQPQSETVWR 128 + W ++N+IDTPGH+DF EV RS+ VLDGA ++ A GVQ Q+ ++ Sbjct: 62 SFQWEN-------TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFH 114 Query: 129 QANKYKVPRLAFVNKMDRTGANFFRAVEQVKTRLGGNPVPIVVPIGAEDTFQGVVDLIEM 188 K +P + F+NK+D+ G + + +K +L V Q V M Sbjct: 115 ALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIK----------QKVELYPNM 164 Query: 189 KAIIWDEASQGMKFEYADIPADLVDTSNEWRTKMVEAAAEASEELMDKYLEEGDLSKEDI 248 + E+ Q + E +++L++KY+ L ++ Sbjct: 165 CVTNFTESEQ------------------------WDTVIEGNDDLLEKYMSGKSLEALEL 200 Query: 249 IAGLRARTLASEIQVMLCGSAFKNKGVQRMLDAVIEFLPSPTEVKAIEGILDDKDETKAS 308 R + + GSA N G+ +++ + S T Sbjct: 201 EQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSSTH----------------- 243 Query: 309 REASDEAPFSALAFKIMNDKFVGNLTFVRVYSGVLKQGDPVYNPVKAKRERIGRIVQMHA 368 ++ FKI + L ++R+YSGVL D V K K +I + Sbjct: 244 ---RGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEK-IKITEMYTSIN 299 Query: 369 NERQDLDEIRAGDIAACVG----LKDVTTGDTLCDEKNIITLERMEFPEPVISLAVEPKT 424 E +D+ +G+I L V GDT + ER+E P P++ VEP Sbjct: 300 GELCKIDKAYSGEIVILQNEFLKLNSV-LGDTKLLPQR----ERIENPLPLLQTTVEPSK 354 Query: 425 KADQEKMSIALGRLAKEDPSFRVRTDEESGQTIIAGMGELHLDIIVDRMKREFGVEANIG 484 +E + AL ++ DP R D + + I++ +G++ +++ ++ ++ VE I Sbjct: 355 PQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIK 414 Query: 485 KPMVAYRETIKKSVEQEGKFVRQTGGKGKFGHVYVRLEPLDVEEAGKEYQFVEEVVGGVV 544 +P V Y E K E + + + + + PL G Q+ V G + Sbjct: 415 EPTVIYMERPLKKA--EYTIHIEVPPNPFWASIGLSVSPL---PLGSGMQYESSVSLGYL 469 Query: 545 PKEFFGAVDKGIQERMKNGVLAGYPVVGIKATLFDGSYHDVDSDELSFKMAGSYAFRDGF 604 + F AV +GI+ + G L G+ V K G Y+ S F+M Sbjct: 470 NQSFQNAVMEGIRYGCEQG-LYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVL 528 Query: 605 MKADPILLEPIMKVEVETPEDYMGDIMGDLNRRRGMVQGMDDLPGGTKAIRAEVPLAEMF 664 KA LLEP + ++ P++Y+ D + + L + E+P + Sbjct: 529 KKAGTELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDT-QLKNNEVILSGEIPARCIQ 587 Query: 665 GYATQMRSMSQGRATYSMEFAKYAET 690 Y + + + GR+ E Y T Sbjct: 588 EYRSDLTFFTNGRSVCLTELKGYHVT 613
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 33.6 bits (77), Expect = 5e-04 Identities = 17/101 (16%), Positives = 35/101 (34%), Gaps = 6/101 (5%) Query: 125 QVNIDGQDSKDGCAPEEVAELVGQMSQLPKIKLRGLMV-IPAPDNTAAFADAKALFDAVK 183 + ++ ++ G P+ V + Q+ + + LM ++ + A A + Sbjct: 121 YLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHFAEAEHPDGISGAMARIEQAA 180 Query: 184 DQHTHPEDWDTLSMGMSSDLEAAIAAGSTMVRVGTALFGAR 224 + S+ S+ A VR G L+GA Sbjct: 181 EGLECR-----RSLSNSAATLWHPEAHFDWVRPGIILYGAS 216
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 40.8 bits (95), Expect = 3e-05 Identities = 25/269 (9%), Positives = 73/269 (27%), Gaps = 7/269 (2%) Query: 312 QQAQNLHTLQQLEPQIQQAQTKFNELIQFFETGQKQYQLAEQELKQTLDFEQQHQQSLNQ 371 + + + L+ + + + + K ++++ + +++L Sbjct: 72 KNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEG 131 Query: 372 VRQSIQERTFIGDEYKKCKEKKNVLEQKLSPLQQQQNTVQQHIAQLEQNQVHLQQQLTQT 431 + + K + L + + + + L Sbjct: 132 AMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEAR 191 Query: 432 QQYAVLDKGLSAHLHQLGQFIQNYEA--IEQQLGNPTLARQKLSEAKSELEQLTASLGTV 489 Q + + + L A + +A + T+ Sbjct: 192 QAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTL 251 Query: 490 EQIELKLEQQRKDKDQKLAQITQ-----LDLIQQKIKIYHELYAELQQFSEKQTQTSAQE 544 E + LE ++ + ++ L I+ L AE + +A Sbjct: 252 EAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANR 311 Query: 545 EQLKTVCQLAEQDYQTTKAEREKLQHILQ 573 + L+ + + + +AE +KL+ + Sbjct: 312 QSLRRDLDASREAKKQLEAEHQKLEEQNK 340 Score = 33.1 bits (75), Expect = 0.007 Identities = 35/246 (14%), Positives = 84/246 (34%), Gaps = 5/246 (2%) Query: 780 LDARAKQLEQQEQLAQHFEQQQQELKMLAANLEQMTKQIDEVDQNLKEITLKGQQNNEKA 839 L K L ++ Q E ++ +L+ + + L+ Sbjct: 101 LRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADL 160 Query: 840 VSLIQQMTGRTDIKPHEWLIEHDAKRQQQQTAYHEAKQRFEQTRQHFEQQKQALDQLKHQ 899 ++ + + +A++ + E ++ E + L+ + Sbjct: 161 EKALEGAMNFST-ADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAE 219 Query: 900 HQHTAEYQQQIDGQIQNWLKTHTDFQAY--DLTALIQINSAQEQDIRNRLNYAERLLSEA 957 A + ++ ++ + T A L A A++ ++ L A + Sbjct: 220 KAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTAD 279 Query: 958 SSALKTMQEQLSEHLQTQPDIEYEKLVSLIQDNIVELKAQLEVRDRLKLKLEVHQQNLAK 1017 S+ +KT++ + + + D+E++ V N L+ L+ K +LE Q L + Sbjct: 280 SAKIKTLEAEKAALEAEKADLEHQSQVL--NANRQSLRRDLDASREAKKQLEAEHQKLEE 337 Query: 1018 QQQYAE 1023 Q + +E Sbjct: 338 QNKISE 343
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 43.6 bits (103), Expect = 5e-07 Identities = 25/159 (15%), Positives = 56/159 (35%), Gaps = 36/159 (22%) Query: 4 NVLITGASGFIGTHLIRFLLEKNYNVIAV-------------TRQA-----------GKA 39 L+TGA+GFIG H+ + LLE + V+ + R Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 40 SDHPALQWVQKFEDISTRQIDYVVNLAGANIGEKRWTESRKKQLIESRVNTTRKLYAWLN 99 +D + + ++ + V + + E+ +S + + Sbjct: 62 ADREGMTDL-----FASGHFERVFISP-HRLAVRYSLENPHA-YADSNLTGFLNILEGCR 114 Query: 100 QSQIFPEVIVSGSAIGYYGIDDQEKWTEVCTEQSPPQPI 138 ++I + S S++ YG++ + ++ + S P+ Sbjct: 115 HNKIQHLLYASSSSV--YGLNRKMPFST---DDSVDHPV 148
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 112 bits (282), Expect = 1e-29 Identities = 70/411 (17%), Positives = 156/411 (37%), Gaps = 70/411 (17%) Query: 25 KRKKFLGFFALILLIAAILYAIWALFLNNSVSTDNAYVGAETAQITSMVSGQVAQVVVKD 84 +R + + +F + L+ A + ++ + + + +I + + V +++VK+ Sbjct: 55 RRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKE 114 Query: 85 TQTVHRGDVLVRIDDR--DAKIALAQAEAELAKAKRQYKQTAANSSSLNS---------- 132 ++V +GDVL+++ +A Q+ A+ ++ Q + S LN Sbjct: 115 GESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEP 174 Query: 133 -------QVVVRADE-----INSAKAQVAQAQADYDKAALE------------------- 161 + V+R ++ + Q Q + + DK E Sbjct: 175 YFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEK 234 Query: 162 --LNRRAQLAASGAVSKEELTKAQSAVETAKAGLELAKAGLAQASSSRKAAESTLAANEA 219 L+ + L A++K + + ++ A L + K+ L Q S +A+ Sbjct: 235 SRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQ 294 Query: 220 LIQGVSETST------PDVQVAQAHVEQAQLDLERTVIRAPVDGVVTRRNIQ-VGQRVAP 272 L + +E ++ + + + + + +VIRAPV V + + G V Sbjct: 295 LFK--NEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTT 352 Query: 273 GTSMMMIVPLND-LYVDANFKESQLKKVRPGQAVTLTSDLYGDDVEYHGKVMGFSGGTGS 331 ++M+IVP +D L V A + + + GQ + + + +G ++G Sbjct: 353 AETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAF--PYTRYGYLVG------- 403 Query: 332 AFALIPAQNATGNWIKVVQRLPVRIALDPKELAEH----PLRVGLSMEAKV 378 I + +V V I+++ L+ PL G+++ A++ Sbjct: 404 KVKNINLDAIEDQRLGLVFN--VIISIEENCLSTGNKNIPLSSGMAVTAEI 452
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 105 bits (264), Expect = 1e-26 Identities = 87/397 (21%), Positives = 161/397 (40%), Gaps = 20/397 (5%) Query: 27 FMVVLDTTIANVSVPHITGNLAVSSTQGTWVVTSYAVAEAICVPLTGWLAGRFGTVRVFI 86 F VL+ + NVS+P I + WV T++ + +I + G L+ + G R+ + Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 87 FGLIGFTIFSFLCGLANS-LGMLVFFRIGQGLCGGPLMPLSQTLLMRIFPQEKHAQAMGL 145 FG+I S + + +S +L+ R QG L ++ R P+E +A GL Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 146 WAMTTVVGPILGPILGGLISDNLSWHWIFFINIP-VGIVCVLAAIRLLKPAETETISLRI 204 +G +GP +GG+I+ + HW + + IP + I+ V ++LLK I Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHYI--HWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDI 201 Query: 205 DTVGLGLLILWIGALQLMLDLGHERDWFNSTSIVVLALTAAIGFVVFLIWELTDKHPVVD 264 G++++ +G + ML F S+ + F++F+ P VD Sbjct: 202 ----KGIILMSVGIVFFMLFTTSYSISFLIVSV--------LSFLIFVKHIRKVTDPFVD 249 Query: 265 VKVFRHRGFAISVLALSLGFGAFFGSIVLIPQWLQM--NLSYTATWAGYLTATMGFGSLT 322 + ++ F I VL + FG G + ++P ++ LS + + + Sbjct: 250 PGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIF 309 Query: 323 MSPIVAKLSTKHDPRALASFGLILLGGVTLMRAFWTTDADFMALAWPQILQGFAVPFFFI 382 I L + P + + G+ L L +F + + + + F Sbjct: 310 -GYIGGILVDRRGPLYVLNIGVTFLSVSFLTASF-LLETTSWFMTIIIVFVLGGLSFTKT 367 Query: 383 PLSNIALGSVLQHEIASAAGLMNFLRTMAGAIGASIA 419 +S I S+ Q E + L+NF ++ G +I Sbjct: 368 VISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIV 404
>cloacin#Cloacin signature. Length = 551 Score = 30.1 bits (67), Expect = 0.012 Identities = 12/39 (30%), Positives = 19/39 (48%) Query: 170 KQVQTESSKEIKTISKEIKQYDEDYHLADKSDDIKELYE 208 + + + E K K Y DYH A K+++IK L + Sbjct: 440 RSAENNLNDEKNKPRKGFKDYGHDYHPAPKTENIKGLGD 478
>TYPE3IMPPROT#Type III secretion system inner membrane P protein family signature. Length = 224 Score = 32.8 bits (75), Expect = 0.001 Identities = 20/107 (18%), Positives = 44/107 (41%), Gaps = 19/107 (17%) Query: 154 VQPIDESELQELRKLSLQQRDKEKLRDFKFASDQESYEQANQIATEKLAQFKHASKQSLL 213 + + L R ++ D+E ++ F+ A + Y + + + + S +LL Sbjct: 88 LSKHVDEGLDGYRDYLIKYSDRELVQFFENAQLKRQYGEETETVKRDKDEIEKPSIFALL 147 Query: 214 WQSLFISFLVS-----FIIAFLLKNFVGLLVSFIVFLILGLVISKVI 255 ++ +S F I F L ++ F+++ LV+S V+ Sbjct: 148 -----PAYALSEIKSAFKIGFYL---------YLPFVVVDLVVSSVL 180
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 50.6 bits (121), Expect = 6e-09 Identities = 38/174 (21%), Positives = 73/174 (41%), Gaps = 1/174 (0%) Query: 41 IATFFDAYTVLAIAFALPQLITEWHLTPAYVGAIIAAGYVGQLVGAIFFGSLAEKVGRLK 100 I +FF + + +LP + +++ PA + A + +G +G L++++G + Sbjct: 21 ILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKR 80 Query: 101 VLSFTILLFVAMDISCLFAWSGMSLLIF-RFLQGVGTGGEVPVASAYINEFIGAEKRGKF 159 +L F I++ + S SLLI RF+QG G + + +I E RGK Sbjct: 81 LLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKA 140 Query: 160 FLLYEVLFPLGLMFAGMAAFFLMPIYGWKVMFIVGLVPSLLVIPLRFFLPESPR 213 F L + +G + W + ++ ++ + V L L + R Sbjct: 141 FGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVR 194
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 96.7 bits (240), Expect = 3e-26 Identities = 51/192 (26%), Positives = 96/192 (50%), Gaps = 3/192 (1%) Query: 3 NVALLQGKKVLVTGAARGLGRDFAQAIAEAGAEVVMADILSDLVQQEAQALQQQGLNVHA 62 N ++GK +TGAA+G+G A+ +A GA + D + +++ +L+ + + A Sbjct: 2 NAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEA 61 Query: 63 VTVDLANADSIENAVAKSVEVLQGLDGLVNCAALATNVGGKNMIDYDPELWDRVMNINVK 122 D+ ++ +I+ A+ + +D LVN A + ++ D E W+ ++N Sbjct: 62 FPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSD---EEWEATFSVNST 118 Query: 123 GTWLISKACVPHLKQSAAGKIINVASDTALWGAPNLMAYVASKGAIVAMTRSMARELGQS 182 G + S++ ++ +G I+ V S+ A ++ AY +SK A V T+ + EL + Sbjct: 119 GVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEY 178 Query: 183 NICVNTLSPGLT 194 NI N +SPG T Sbjct: 179 NIRCNIVSPGST 190
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 44.4 bits (105), Expect = 5e-07 Identities = 72/363 (19%), Positives = 130/363 (35%), Gaps = 26/363 (7%) Query: 52 AKLGWLMTSFLLAYGFSSVFLSFLGDIFNPKKMLFWSVTSWGVLMFCMGFTTSYSGMLVL 111 A G L+ + L + L L D F + +L S+ V M + + Sbjct: 43 AHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIG 102 Query: 112 RVLLGLAEGPLFALAYTIVKQTYTDRQQARASTMFLLGTPIGA-FLGFPITANVLAHHDW 170 R++ G+ I T RA + G + P+ ++ Sbjct: 103 RIVAGITGATGAVAGAYIADIT---DGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSP 159 Query: 171 HTTFFVMAALTLIAIFSIVFGLRNLQL--KKTVEIEGESKRTNFKGHITNTKLLLSNSAF 228 H FF AAL + + F L ++ + E + +F+ T + + F Sbjct: 160 HAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVF 219 Query: 229 WLVCLFNIALMTYLWGLNS-----WVPSYLMQDKGFNLKEFGMYSSFPFIAMLIGEIIGA 283 +++ L LW + W + G +L FG+ S AM+ G Sbjct: 220 FIMQLVGQVPAA-LWVIFGEDRFHWDAT----TIGISLAAFGILHSL-AQAMITG----- 268 Query: 284 FLSDKLGRRAIQVFSGLLLAGIFMYVMVIMTEPLLIIAAMSLSAMAWGFGVAAVFALLAR 343 ++ +LG R + G++ G ++ T + M L A + G G+ A+ A+L+R Sbjct: 269 PVAARLGERRA-LMLGMIADGTGYILLAFATRGWMAFPIMVLLA-SGGIGMPALQAMLSR 326 Query: 344 VTTSNVGATAGGIFNGLGNFASAIAPVLIGYIVMQTHSFNLGITFLAAVAVIGSLFLVPL 403 G L + S + P+L I + + G ++A A+ L +P Sbjct: 327 QVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASITTWNGWAWIAGAALY--LLCLPA 384 Query: 404 LKR 406 L+R Sbjct: 385 LRR 387
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 101 bits (253), Expect = 7e-28 Identities = 69/259 (26%), Positives = 116/259 (44%), Gaps = 12/259 (4%) Query: 5 VEGKVAVVTGGSSGIGLAAVEILVAEGAKVAW--CGRDEERLNASKHYILEKFPHANIFT 62 +EGK+A +TG + GIG A L ++GA +A ++ S + A Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 63 KACNVLKKEEVQQFAKEVKLNLGNVDMLINNAGQGRVSNFENTQDEDWMKEIELKYFSVL 122 + E + +E+ G +D+L+N AG R + DE+W + V Sbjct: 66 VRDSAAIDEITARIEREM----GPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVF 121 Query: 123 HPVRAFLDDLKQSANASITNVNSLLALQPEPHMIATSSARAALLNLTHSLAHEFTQYGVR 182 + R+ + + SI V S A P M A +S++AA + T L E +Y +R Sbjct: 122 NASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIR 181 Query: 183 VNSILLGMVESA-QWKRRYETRSDLNLSWEEWTGNIAKNR-GIPMQRLGRPEEPARALVF 240 N + G E+ QW +D N + + G++ + GIP+++L +P + A A++F Sbjct: 182 CNIVSPGSTETDMQW----SLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLF 237 Query: 241 LASPLASYTTGSAIDVSGG 259 L S A + T + V GG Sbjct: 238 LVSGQAGHITMHNLCVDGG 256
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 31.6 bits (71), Expect = 0.013 Identities = 26/236 (11%), Positives = 70/236 (29%), Gaps = 9/236 (3%) Query: 64 QKDSLTEEIDHDNLYQYGTVAKIVQVVNHENDENCIKVLIEGLHRSKLEKIIDEDSHLTA 123 + + D + + + E L + + Sbjct: 150 KAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTAD 209 Query: 124 EHSLSPMTINVDKATQETRLQELRTLFAQYAEAKLRNARELVAAANKIEDLLQLMFFVAT 183 + T+ +KA R +L ++ ++ + L + Sbjct: 210 SAKIK--TLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEK 267 Query: 184 RVP-LNIEIKQKFLEHDEFEAHLQELMSYLVNQSAEQQIEQTLHDSVKRQMEKNQREYFL 242 + + EA L + + + Q+ S++R ++ ++ Sbjct: 268 ALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAK-- 325 Query: 243 NEKMKVIQRELSDMNGGAEDDVAEIEKRLAEADLPEHVRKKAEAEFRKLKAMQPAS 298 ++++ ++L + N +E + + L + +K+ EAE +KL+ S Sbjct: 326 -KQLEAEHQKLEEQNKISEASRQSLRRDLDAS---REAKKQLEAEHQKLEEQNKIS 377
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 41.4 bits (97), Expect = 6e-06 Identities = 77/424 (18%), Positives = 152/424 (35%), Gaps = 55/424 (12%) Query: 12 NQQRAKHNKTRYYILAMIFLVTSLNYGDRATLSMAAAPMSQELGLSSVTMGYIFSAFGWA 71 +Q +HN+ ++ + F + L+++ ++ + + ++ +AF Sbjct: 6 SQSNLRHNQILIWLCILSFFSVL----NEMVLNVSLPDIANDFNKPPASTNWVNTAFMLT 61 Query: 72 YVIGQIPGGWLLDKFGARRVYFWSIMLWSFFTILLGFVDILGSIPLIIASLFLLRFLVGL 131 + IG G L D+ G +R+ + I I+ F ++G + SL ++ + Sbjct: 62 FSIGTAVYGKLSDQLGIKRLLLFGI-------IINCFGSVIGFVGHSFFSLLIMARFIQG 114 Query: 132 SESPAFPGNSQIVAAWFPTKERGTAAAIFNSAQYFATVIFAPFMGWLVAH-IHWQSVFWI 190 + + AFP +V A + KE A + P +G ++AH IHW + I Sbjct: 115 AGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLI 174 Query: 191 MGGLGIVIAFIWLKVIYSPEKHPTINSNEFKYLQAGGAITSMGENQLKIADENNKMNF-- 248 + I+ +K++ + F G + S+G + + ++F Sbjct: 175 PM-ITIITVPFLMKLLKKEVRI----KGHFDI--KGIILMSVGIVFFMLFTTSYSISFLI 227 Query: 249 ----------KNIKK---------LLSSRMLLGIFIAQYCITCLTYFFITWFPVYLVKER 289 K+I+K L + + + I F++ P + Sbjct: 228 VSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVH 287 Query: 290 HMSILEAGFAAVLPA-LCGFIGGVLGGVISDK---LIKMNKSLTFSRKFPIIFGMLLSTS 345 +S E G + P + I G +GG++ D+ L +N +TF + LL T+ Sbjct: 288 QLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETT 347 Query: 346 IVVCNYVDSQTAILFFMSLAFFGKGFGALGWAVMSDVAPKEMVGLSGGLFNT---FGNTA 402 + + L+F + V S + +E G L N Sbjct: 348 SWFMTII----IVFVLGGLSFTKT---VISTIVSSSLKQQE-AGAGMSLLNFTSFLSEGT 399 Query: 403 GIVI 406 GI I Sbjct: 400 GIAI 403
>PF07520#Virulence protein SrfB Length = 1041 Score = 29.6 bits (66), Expect = 0.004 Identities = 9/36 (25%), Positives = 18/36 (50%), Gaps = 1/36 (2%) Query: 42 NPRGTVE-GGMICAMLDDVMGLFAFLANDSKPATTI 76 +P+ TV GGM+ A+ ++ + F + +T Sbjct: 858 DPKSTVAVGGMLIALSENRIPNFKVTTGAFQMKSTA 893
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 35.2 bits (81), Expect = 4e-04 Identities = 26/110 (23%), Positives = 45/110 (40%), Gaps = 15/110 (13%) Query: 125 LDAGRVIVVAGFQG----FDANGNTTTLGRGGSDTSGVALAAALKADECQIYTDVDGVYT 180 ++ G +++ +G G + D +G LA + AD I TDV+G Sbjct: 183 VERGVIVIASGGGGVPVILEDGEIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVNGAAL 242 Query: 181 TDPRVAPKAKKIDRISFEEMLEMA--------SLGSKVLQ-IRSVEFAGK 221 K + + + EE+ + S+G KVL IR +E+ G+ Sbjct: 243 YYGT--EKEQWLREVKVEELRKYYEEGHFKAGSMGPKVLAAIRFIEWGGE 290
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 94.0 bits (233), Expect = 5e-25 Identities = 66/268 (24%), Positives = 109/268 (40%), Gaps = 25/268 (9%) Query: 3 NRQRFTDKVVIVTGSAQGIGRGVALQVATEGGQVIMAD-RSEYVEDVLKEIQSTGGDAVT 61 N + K+ +TG+AQGIG VA +A++G + D E +E V+ +++ A Sbjct: 2 NAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEA 61 Query: 62 INADLETYAGAQAVVAIAIEHYGRIDILINNVGGAIWMKPFEEFSEEEIIKEVNRSLFPT 121 AD+ A + A G IDIL+ NV G + S+EE + + Sbjct: 62 FPADVRDSAAIDEITARIEREMGPIDILV-NVAGVLRPGLIHSLSDEEWEATFSVNSTGV 120 Query: 122 LWCCRAVLPAMIKQQAGVIVNVSSIA--TRGINRIPYSASKGGVNALTASLAFEHAKDGI 179 R+V M+ +++G IV V S + Y++SK T L E A+ I Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNI 180 Query: 180 RVNAVATGGTEAPPRKVPRNANPLSQNEKDWMQQVVDQTIDRTF---------MGRYGTI 230 R N V+ G TE W + + + + + + Sbjct: 181 RCNIVSPGSTET------------DMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKP 228 Query: 231 QEQVNAILFLASDEASYMTGSVISVGGG 258 + +A+LFL S +A ++T + V GG Sbjct: 229 SDIADAVLFLVSGQAGHITMHNLCVDGG 256
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 29.3 bits (65), Expect = 0.028 Identities = 16/41 (39%), Positives = 25/41 (60%), Gaps = 1/41 (2%) Query: 247 VTNDFDLVALE-KLNELQAKFPWFEYRTVVASPESNHERKG 286 +T D+DL AL L E++ + P E+ VV +P S ++KG Sbjct: 488 LTADYDLFALAPSLTEIKKQIPQKEWDKVVNTPNSLEKQKG 528
>PF05932#Tir chaperone protein (CesT) Length = 127 Score = 29.0 bits (65), Expect = 0.017 Identities = 9/52 (17%), Positives = 15/52 (28%) Query: 253 AGSWGKQGGGSYGFENGHMLLWTQWANPEDRPNFPKADEYTEKYGEAMSKWM 304 A + G G + L + P ++ + P E M W Sbjct: 72 ALNPLLNAGPGLGLDEKSGLYHAYQSIPREKLSVPTLKREMAGLLEWMRGWR 123
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 408 bits (1049), Expect = e-140 Identities = 137/372 (36%), Positives = 207/372 (55%), Gaps = 26/372 (6%) Query: 210 PEPMEKELIALQAELFELKKSIYSDSEADYQLFSSVGKSASYKQVCALLTKAAGSKVSIL 269 P + + + + L E K+ + VG+SA+ +++ +L + + ++++ Sbjct: 105 PFDLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLM 164 Query: 270 LQGETGVGKEAFARGVHANSQRKDQPFIAVNCAAIPPELIESELFGVEKGAYTGAHQSRL 329 + GE+G GKE AR +H +R++ PF+A+N AAIP +LIESELFG EKGA+TGA Sbjct: 165 ITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRST 224 Query: 330 GKFERANGGTIFLDEVIELSPRAQAALLRILQEGEFERVGDSQTRILDVRVITATNEDLE 389 G+FE+A GGT+FLDE+ ++ AQ LLR+LQ+GE+ VG DVR++ ATN+DL+ Sbjct: 225 GRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLK 284 Query: 390 QAVKTGRFRADLYYRLNIFPVQIPPLRERREDIPLLVEHFLHRFEKMYGKTIQGVSEKTK 449 Q++ G FR DLYYRLN+ P+++PPLR+R EDIP LV HF+ + EK G ++ ++ Sbjct: 285 QSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKE-GLDVKRFDQEAL 343 Query: 450 VFMQQYEWPGNIRELENLLERAVLLTDDQQL------IKLNAIFPQIKHDPEQA------ 497 M+ + WPGN+RELENL+ R L + +L + P + A Sbjct: 344 ELMKAHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLS 403 Query: 498 --VVVETDFEQLLQAEFN-----------LEEHEKQLILTALKKANHNVSEAARLLGLTR 544 VE + Q + + L E E LIL AL N +AA LLGL R Sbjct: 404 ISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNR 463 Query: 545 AALDYRIKKFQL 556 L +I++ + Sbjct: 464 NTLRKKIRELGV 475
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 33.3 bits (76), Expect = 0.002 Identities = 20/113 (17%), Positives = 44/113 (38%), Gaps = 6/113 (5%) Query: 258 EKDRTILDEIAHRSFDTPSKVIAGIRNHIVERVQEAVDSMQTIKLLSQHQITTYQSKNDQ 317 E++ L + F T ++ ++ E ++ ++ +S+ D Sbjct: 181 EEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAE-RLTVLARINRYENLSRVEKSRLDD 239 Query: 318 LLHHIKSLAQSQLSSAHRLLDQMKERIQFSSQQQVKFS-LAQIESLMKEILLQ 369 SL Q + H +L+Q + ++ ++ +V S L QIES + + Sbjct: 240 F----SSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEE 288
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 55.0 bits (132), Expect = 1e-11 Identities = 14/56 (25%), Positives = 21/56 (37%) Query: 12 KVLHVAKELFNQYGFHKVGVDRIISEAKVSKATFYNAFHSKERLIERCISFQKDTL 67 +L VA LF+Q G + I A V++ Y F K L + + Sbjct: 15 HILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNI 70
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 32.9 bits (75), Expect = 0.002 Identities = 45/224 (20%), Positives = 80/224 (35%), Gaps = 11/224 (4%) Query: 25 VILLFAIASGASVANVYYAQPLLDILARDFNVSHAAIGGVVTATQIGCALALIFLVPLGD 84 +++ I S SV N L +A DFN A+ V TA + ++ L D Sbjct: 15 ILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSD 74 Query: 85 LVNRRRLMALQLLALIFALLAVGFAHSTI-ILLAGMLAVGLLGTAMTQGLIAYAAGAALP 143 + +RL+ ++ F + HS +L+ G A ++ A Sbjct: 75 QLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPK 134 Query: 144 HEQGHVVGTAQSGVFIGLLLARVFSGGISDVAGWRGVYFCAAIIMLMIALPLWKRLP--- 200 +G G S V +G + G I+ W Y ++ +I +P +L Sbjct: 135 ENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKE 192 Query: 201 -----HLNIQPSAMRYPQLLASMLKLLRQEKVLQVRGVLALLMF 239 H +I+ + ++ ML + VL+ L+F Sbjct: 193 VRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIF 236
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 211 bits (538), Expect = 2e-66 Identities = 87/365 (23%), Positives = 162/365 (44%), Gaps = 51/365 (13%) Query: 21 PPLPRASLVIWIVGIGLVIFFIWAWVFKLEEVSTGTGKVIPSSKEQVIQSLEGGILTKLN 80 P R LV + + LVI FI + + ++E V+T GK+ S + + I+ +E I+ ++ Sbjct: 52 PVSRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEII 111 Query: 81 VQEGDIVQKGEILAQLDPTRFASNVGESKSLLISAQATAARLRAEVN------------- 127 V+EG+ V+KG++L +L ++ +++S L+ A+ R + Sbjct: 112 VKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLP 171 Query: 128 ---GTPLVFPEIVMKEPKLVQEETALYRSRRADLEQTLAGLR--------------QALQ 170 V E V++ L++E+ + +++++ E L R + Sbjct: 172 DEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSR 231 Query: 171 LVQQELAMTEPLVAKGAASEVEVLRLRREANDLQNKMNDAQNQ----------------- 213 + + L L+ K A ++ VL + + N++ ++Q Sbjct: 232 VEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQL 291 Query: 214 ----YYVKAREELSKANTDSETQQQIVLGRSDSLDRAVFRAPVRGVVKEIAVTTRGGVVP 269 + + ++L + + + + +V RAPV V+++ V T GGVV Sbjct: 292 VTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVT 351 Query: 270 QNGKLMTIVPIDEQLLIEARILPRDIAFIRPGQEALVKITAYDYSIYGGLKGKVTVISPD 329 LM IVP D+ L + A + +DI FI GQ A++K+ A+ Y+ YG L GKV I+ D Sbjct: 352 TAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLD 411 Query: 330 TIRDE 334 I D+ Sbjct: 412 AIEDQ 416
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 62.2 bits (151), Expect = 2e-15 Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 2/59 (3%) Query: 7 YYRVYIRTDSDKLYNKEGKAFGITPGMVATVDIRTGQKTVLDYLLKPF-NKAKEALRER 64 + V I + + L + K ++ GM T +I+TG ++V+ YLL P E+LRER Sbjct: 421 VFNVIISIEENCL-STGNKNIPLSSGMAVTAEIKTGMRSVISYLLSPLEESVTESLRER 478
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 46.9 bits (111), Expect = 6e-09 Identities = 25/181 (13%), Positives = 57/181 (31%), Gaps = 14/181 (7%) Query: 12 QVINTSIDLFQHHGFHTVGVDRIVKESKITKATFYNFFHSKERFIEICLIVQKERLKEKV 71 +++ ++ LF G + + I K + +T+ Y F K + + + E Sbjct: 15 HILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELE 74 Query: 72 VSIVEYDQGLSVKEKLKKLYFLHTDL--EGLYYLLFKAMFEIKLTYPKAYITAVRYRTWL 129 + G + + L + E LL + +F + + R Sbjct: 75 LEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRNLC 134 Query: 130 INEIYSQLRAFKKDA-------TFQDAKLFLYMIEGIIIQLLSS----DGAVDREKVLDC 178 + E Y ++ K + ++ G I L+ + + D +K Sbjct: 135 L-ESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLKKEARD 193 Query: 179 F 179 + Sbjct: 194 Y 194
>56KDTSANTIGN#Rickettsia 56kDa type-specific antigen protein signature. Length = 533 Score = 28.8 bits (64), Expect = 0.038 Identities = 31/125 (24%), Positives = 46/125 (36%), Gaps = 25/125 (20%) Query: 83 SIGSGNPHAADNSTATVSMALLLSAADHSQWR--------MKLNNFPYYFPTRNAEGFLA 134 +I GNP+ + + +H QWR + N P P + + Sbjct: 210 NIPQGNPNPVGQPPQRANQPANFAIHNHEQWRSLVVGLAALSNANKPSASPVKVLSDKII 269 Query: 135 Q-QKAFKP--------VPATGKPDPALVEAFLKEYPEARKSIEQKAKMPLTGSFSGAEFY 185 Q KP VP TG P+ A +E + E ++E+ L SF G Y Sbjct: 270 QIYSDIKPFADIAGINVPDTGLPNSASIEQIQSKIQELGDTLEE-----LRDSFDG---Y 321 Query: 186 VVNAF 190 + NAF Sbjct: 322 INNAF 326
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 49.6 bits (118), Expect = 9e-10 Identities = 32/177 (18%), Positives = 54/177 (30%), Gaps = 12/177 (6%) Query: 1 MAGRPRE---FDREEALVKARDFFWLHGYEGTSMSDLVEVLGIASARIYKAFGSKEALFR 57 MA + ++ R+ L A F G TS+ ++ + G+ IY F K LF Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 58 EAVNHYEKNEGNFALNALKQKNIKDAISQLFADALALYTQANHSYGCMVVSAASVLGEEN 117 E E N G + K D +S L + + ++ + Sbjct: 61 EIWELSESNIGE-LELEYQAKFPGDPLSVLREILIHVLESTVT--EERRRLLMEIIFHKC 117 Query: 118 QAVLEWMKAQRIARG------QSLVDRFIQAKSDGQLVAEADPKTLGQYYALVLHGL 168 + V E Q+ R + L A+ + + GL Sbjct: 118 EFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGL 174
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 52.7 bits (126), Expect = 8e-11 Identities = 31/189 (16%), Positives = 74/189 (39%), Gaps = 14/189 (7%) Query: 8 RGRPREFDLDNALDKAMDVFRFQGFHATSISDLSKAMNLTVGSIYKAFGDKHNLFYQVFN 67 + + LD A+ +F QG +TS+ +++KA +T G+IY F DK +LF +++ Sbjct: 8 EAQETRQHI---LDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 68 R-YLLLRKKELNKYLSHANTGYEKIQNLLNFYIDSVKELEGKKGCLVVGSAIEIEV---- 122 + + EL ++ +L ++S E ++ + + V Sbjct: 65 LSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMA 124 Query: 123 LNHELTKAIEFALNKNLSNIKKLIEEGKADGSINQELNVDQAASLLLCLVLGI---RVAG 179 + + + + I++ ++ + +L +AA ++ + G+ + Sbjct: 125 VVQQAQRNLCLES---YDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFA 181 Query: 180 KTSSTRPND 188 S + Sbjct: 182 PQSFDLKKE 190
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 115 bits (290), Expect = 2e-33 Identities = 80/259 (30%), Positives = 125/259 (48%), Gaps = 17/259 (6%) Query: 2 LNKLSLTGKIALVTGGSRSIGAEIVKKLAAHGATVAFTYHASQKKAEELVKEIEFYGGQG 61 +N + GKIA +TG ++ IG + + LA+ GA +A + +K E++V ++ Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIA-AVDYNPEKLEKVVSSLKAEARHA 59 Query: 62 LAIKADAGNPEMVIHAVAEVARKFNKIDILVNNAGISHLGSLEAVTIADFERLVAVNITG 121 A AD + + A + R+ IDILVN AG+ G + +++ ++E +VN TG Sbjct: 60 EAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTG 119 Query: 122 VFLTTRESLKHM--GKGGRIINIGSTMVNYSGFSGASIYILTKGAITGFSKGLVRELGTK 179 VF +R K+M + G I+ +GS S A+ Y +K A F+K L EL Sbjct: 120 VFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAA-YASSKAAAVMFTKCLGLELAEY 178 Query: 180 GITINTIHPGPTNSDMNPS------------DGPIANLLLPNIAVGRYGEGVDIANSVLF 227 I N + PG T +DM S G + I + + + DIA++VLF Sbjct: 179 NIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKT-GIPLKKLAKPSDIADAVLF 237 Query: 228 LASEDASYISGAELSVDGG 246 L S A +I+ L VDGG Sbjct: 238 LVSGQAGHITMHNLCVDGG 256
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 45.0 bits (106), Expect = 3e-08 Identities = 11/60 (18%), Positives = 22/60 (36%) Query: 12 QVINKSIHLFHHHGFHTVGVDRIVKECEVTKATFYNFFHSKERFIEICLIVQKERLKEKV 71 +++ ++ LF G + + I K VT+ Y F K + + + E Sbjct: 15 HILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELE 74
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 28.6 bits (64), Expect = 0.032 Identities = 24/133 (18%), Positives = 44/133 (33%), Gaps = 36/133 (27%) Query: 32 MRIAVTGATGQLGQFVISQLLERTEAKNIVAL---------VRNPEKALDLSSKGVEVRP 82 M+ VTGA G +G V +LLE +V + + L+ G + Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQ--VVGIDNLNDYYDVSLKQARLELLAQPGFQFHK 58 Query: 83 FDYVNDVEKLSE--QLQGIDKLL-----------------LISSNEIGQRTVQHQNIINA 123 D + D E +++ +++ SN G NI+ Sbjct: 59 ID-LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTG-----FLNILEG 112 Query: 124 AKLAHVKFIAYTS 136 + ++ + Y S Sbjct: 113 CRHNKIQHLLYAS 125
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.5 bits (74), Expect = 0.004 Identities = 13/49 (26%), Positives = 24/49 (48%) Query: 509 APINGVISAWKVEDGEQVTEGQVVAIMEAMKMEVQVLAHRSGVIQIGAE 557 N ++ V++GE V +G V+ + A+ E L +S ++Q E Sbjct: 101 PIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLE 149
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 45.4 bits (107), Expect = 2e-08 Identities = 12/49 (24%), Positives = 15/49 (30%) Query: 3 RTLHTATDLFKQYGFHKVGVDRIIAEAQTSKATFYNAFHSKERLIERCL 51 L A LF Q G + I A ++ Y F K L Sbjct: 15 HILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIW 63
>cloacin#Cloacin signature. Length = 551 Score = 30.8 bits (69), Expect = 0.031 Identities = 23/90 (25%), Positives = 38/90 (42%), Gaps = 5/90 (5%) Query: 288 EIDSFLKENKDGFSNEHKLQTMTLIDNMKQNLVANSIQAKFKIIDSNEQQRKKITEPYLQ 347 EI F + D + H++ M + + N+ QA F + E+ L Sbjct: 371 EIKQFNRFAHDPMAGGHRMWQMAGLKAQRAQTDVNNKQAAFDAA-AKEKSDADAA---LS 426 Query: 348 AAIQRAERMGDK-KGLENLKNFEKNAPAKA 376 +A++ ++ DK + EN N EKN P K Sbjct: 427 SAMESRKKKEDKKRSAENNLNDEKNKPRKG 456
>FRAGILYSIN#Fragilysin metallopeptidase (M10C) enterotoxin signature. Length = 405 Score = 28.9 bits (64), Expect = 0.020 Identities = 16/50 (32%), Positives = 23/50 (46%), Gaps = 7/50 (14%) Query: 48 LTSSPILLMAGKAKDGITFIGEIDKYPLVGQFTTARFEENDELIAVISEK 97 L + + L G+ KD +FI L +F RF N E I+ I+ K Sbjct: 93 LDNENVRLFNGRDKDSTSFI-------LGDEFAVLRFYRNGESISYIAYK 135
>BONTOXILYSIN#Bontoxilysin signature. Length = 1196 Score = 32.6 bits (74), Expect = 0.009 Identities = 35/171 (20%), Positives = 65/171 (38%), Gaps = 26/171 (15%) Query: 500 SNKFTMITKSLIDNQNLKITFNNKIKSVIIEKIN-----KNINYGTEFTIEIDIEKLPQN 554 S F I +D Q++K FN++++ V+ E ++ + G I DI Sbjct: 800 SYTFKTIDFKFLDIQSIKNFFNSQVEQVMKEILSPYQLLLFASKGPNSNIIEDISGKNTL 859 Query: 555 IYYSYEQESLMDERLKGFDFTDKNSNLSFVETIKVTDSINNF--------LLNSPISSNL 606 I Y+ E + + N + F NNF + + L Sbjct: 860 IQYTESIELVYGVNGESLYLKSPNETIKFSNKFFTNGLTNNFTICFWLRFTGKNDDKTRL 919 Query: 607 NTNKKDN---KVYFDQETSILFNIIEFGDFDSRNSYKNYFRGQEFSDLYTD 654 NK +N ++YF ++ ++F II DS + ++ + S++ D Sbjct: 920 IGNKVNNCGWEIYF-EDNGLVFEII-----DSNGNQESVY----LSNIIND 960
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 43.8 bits (103), Expect = 1e-08 Identities = 11/49 (22%), Positives = 24/49 (48%) Query: 48 HVINKSIDLFHHRGFHTVGVDRIVKECEITKATFYNFFHSKERLRAQAF 96 H+++ ++ LF +G + + I K +T+ Y F K L ++ + Sbjct: 15 HILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIW 63
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 46.9 bits (111), Expect = 7e-09 Identities = 24/181 (13%), Positives = 56/181 (30%), Gaps = 12/181 (6%) Query: 12 HVINKSIDLFHHRGFHTVGVDRIVKECEITKATFYNFFHSKERFIEICLIVQKERLKEKV 71 H+++ ++ LF +G + + I K +T+ Y F K + + + E Sbjct: 15 HILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELE 74 Query: 72 VSIVEYAQDTSAADKLKQLYFLHTD--VEGMYYLLFKAMFETKLSYPKAYITAVRYRTW- 128 + + + L + E LL + +F + + R Sbjct: 75 LEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRNLC 134 Query: 129 -----LLNEIYSQLIKLKTDATFQDAKLFLYMIEGAIIQLLSS----DGAIDQEKMLDCF 179 + + I+ K + ++ G I L+ + + D +K + Sbjct: 135 LESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLKKEARDY 194 Query: 180 F 180 Sbjct: 195 V 195
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 40.2 bits (94), Expect = 1e-05 Identities = 68/400 (17%), Positives = 130/400 (32%), Gaps = 35/400 (8%) Query: 38 IFAFLTLLCDGADLGFLALSLTSLKTEFHLTGVQAGTLGSL----TLFGSAVGGLIGGWA 93 I T+ D +G + L L + + G L L A ++G + Sbjct: 8 IVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALS 67 Query: 94 CDRFGRVRIIVFFIAYSSVLTSALGFTDSYMQFAVLRTFGAMGLGALYIACNILMSEMVP 153 DRFGR +++ +A ++V + + + R + GA ++++ Sbjct: 68 -DRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGIT-GATGAVAGAYIADITD 125 Query: 154 TKHRSTVL----ATLMTGYTLGSLLATLLAG--HIIPEHGWRFLYWIAIAPVVLSVLMHF 207 R+ A G G +L L+ G P + A + + F Sbjct: 126 GDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAP------FFAAAALNGLNFLTGCF 179 Query: 208 CVPEPESWKKARQLKALEVAQSNQPKKRQNPYFEILRDKKHGTMFVLWIIS-TGALQFGY 266 +PE + + L N + + F++ ++ A + Sbjct: 180 LLPES----HKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVI 235 Query: 267 YGVSNWLPAYLESDLGIKFKEMAMYMVGTFLIMMFAKVIAGIVADKLGRRAVFAFGTIGT 326 +G + + + +GI L + +I G VA +LG R G I Sbjct: 236 FGEDRF--HWDATTIGI------SLAAFGILHSLAQAMITGPVAARLGERRALMLGMIAD 287 Query: 327 AL-FIPVIVYLNTPTNILWMMLFFGFLYGIPYAINATYMTESFPTSIRGSAVGGAYNIGK 385 +I + M+L G+P A+ A ++ +G G + Sbjct: 288 GTGYILLAFATRGWMAFPIMVLLASGGIGMP-ALQA-MLSRQVDEERQGQLQGSLAALTS 345 Query: 386 VLSIFSPLTIGYL-SQNGSIGLGLLVMAAAYFICGVIPLL 424 + SI PL + + + + G +A A +P L Sbjct: 346 LTSIVGPLLFTAIYAASITTWNGWAWIAGAALYLLCLPAL 385
>OUTRMMBRANEA#Outer membrane protein A signature. Length = 346 Score = 31.4 bits (71), Expect = 0.007 Identities = 12/46 (26%), Positives = 24/46 (52%), Gaps = 2/46 (4%) Query: 281 KVSWGAGGGLKYQLTPQQSVQANYQYI--VGDQKFMPYTTQSGLAN 324 VS GG++Y +TP+ + + YQ+ +GD + +G+ + Sbjct: 139 GVSPVFAGGVEYAITPEIATRLEYQWTNNIGDAHTIGTRPDNGMLS 184
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 106 bits (265), Expect = 2e-29 Identities = 76/256 (29%), Positives = 119/256 (46%), Gaps = 17/256 (6%) Query: 44 LKDKVAVISGGDSGIGRSVAVLFAREGADI-AILYLEEDQDAEITKQLVEREGQHCLLLK 102 ++ K+A I+G GIG +VA A +GA I A+ Y E E ++ E +H Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKL--EKVVSSLKAEARHAEAFP 63 Query: 103 GDISDPDVAKLDIDKVLQHYGKINILVNNAGVQYQQKEIESISNEQLEKTFKTNIFPMFY 162 D+ D ++ + G I+ILVN AGV + I S+S+E+ E TF N +F Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGV-LRPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 163 LTKEAIPYM--EEGDSIINTTSITSYQGHDELIDYASTKGAITTFTRSLSNNLMKQKKGI 220 ++ YM SI+ S + + YAS+K A FT+ L L + I Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEY--NI 180 Query: 221 RVNGVAPGPI-----WTPLIPSSFDAETVKEFGKD----TPMGRMGQPSEVAPAYLFLAS 271 R N V+PG W+ + + +K + P+ ++ +PS++A A LFL S Sbjct: 181 RCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVS 240 Query: 272 DDASYITGQVIHVNGG 287 A +IT + V+GG Sbjct: 241 GQAGHITMHNLCVDGG 256
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 55.2 bits (133), Expect = 9e-10 Identities = 23/113 (20%), Positives = 49/113 (43%), Gaps = 11/113 (9%) Query: 929 RKRILVVDNEAVDRGLVANFLKPLGFMIEEAESGIDCLRRVPIFQPNLILMDLNMPLMGG 988 ILV D++A R ++ L G+ + + R + +L++ D+ MP Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 989 WETARLLRQNNITNVPILIISANAGEREVNPQDAVLS-----EDFMLKPIDLN 1036 ++ +++ ++P+L++SA A+ + D++ KP DL Sbjct: 63 FDLLPRIKKAR-PDLPVLVMSAQN-----TFMTAIKASEKGAYDYLPKPFDLT 109
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 82.6 bits (204), Expect = 1e-19 Identities = 28/137 (20%), Positives = 63/137 (45%), Gaps = 2/137 (1%) Query: 19 ILIVDDVPENLGLLHESLDQAGYRVLVTTDGLSAIEIAHRCLPDMILLDGNMPHMDGFES 78 IL+ DD +L+++L +AGY V +T++ + D+++ D MP + F+ Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 79 CIQLKASPITQFIPIIFMTGLSETEHIVRGFQVGGVDYVTKPLNIEEVLARVKTHLAHAK 138 ++K +P++ M+ + ++ + G DY+ KP ++ E++ + LA K Sbjct: 66 LPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 139 LLQQQKQVIDATETAIL 155 + + ++ Sbjct: 124 RRPSKLEDDSQDGMPLV 140
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 32.6 bits (74), Expect = 9e-05 Identities = 12/43 (27%), Positives = 22/43 (51%), Gaps = 2/43 (4%) Query: 25 EMTYTWAGESMLIIDATDVNENYRGQGVGRQLLDALVAFVREK 67 ++ W G +I+ V ++YR +GVG LL + + +E Sbjct: 81 KIRSNWNG--YALIEDIAVAKDYRKKGVGTALLHKAIEWAKEN 121
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 93.2 bits (231), Expect = 6e-25 Identities = 67/252 (26%), Positives = 107/252 (42%), Gaps = 12/252 (4%) Query: 3 ISRKTALVTGASRGIGRAIAEHLAQDGFYVIVNYAGNKVHAQATVEHIIEQGGQASAIQA 62 I K A +TGA++GIG A+A LA G ++ N + V + + A A A Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHI-AAVDYNPEKLEKVVSSLKAEARHAEAFPA 64 Query: 63 DVANEHEVSRLFQEAKAINGQLDVVVHSAGIMPMAKITPESLPDFDKVIHTNLRGSFLIL 122 DV + + + + G +D++V+ AG++ I S +++ N G F Sbjct: 65 DVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNAS 124 Query: 123 AHAAETVPD--GGRIIALSTSVIAKSFPAYGPYIASKAGVEGLVHVLANELRGRNITVNA 180 ++ + D G I+ + ++ + Y +SKA L EL NI N Sbjct: 125 RSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184 Query: 181 VAPGPTGTD----LFYNGKTDEQV----AAIAKLA-PLERIGTPEEIAGIVAMLAGPDGG 231 V+PG T TD L+ + EQV K PL+++ P +IA V L G Sbjct: 185 VSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAG 244 Query: 232 WINSQVIRVNGG 243 I + V+GG Sbjct: 245 HITMHNLCVDGG 256
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 32.5 bits (74), Expect = 0.003 Identities = 42/185 (22%), Positives = 76/185 (41%), Gaps = 13/185 (7%) Query: 4 NTMHRQVLILASSQSLFQTVSVMVMTIGGLAGANIANTPTLSTLPIASMF-LGTALMMFP 62 N H Q+LI S F ++ MV+ + AN N P ST + + F L ++ Sbjct: 9 NLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAV 68 Query: 63 ASILMAHIGRRNGFLFGAFLGVLGGIIASIGIFYSSLMLLALGTLCVGAYQSFAQFYRFA 122 L +G + LFG + G +I +G + SL+++A GA A F Sbjct: 69 YGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGA----AAFPALV 124 Query: 123 AIEVAN---DAFRSRAISWVMAGGIVAALIGPTLARFGGPLFQHLEYIGSFLIISIISLV 179 + VA R +A + + + +GP + GG + ++ + S+L++ + + Sbjct: 125 MVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAI---GGMIAHYIHW--SYLLLIPMITI 179 Query: 180 AMGIL 184 Sbjct: 180 ITVPF 184
>BACYPHPHTASE#Salmonella/Yersinia modular tyrosine phosphatase signature. Length = 468 Score = 30.9 bits (69), Expect = 0.002 Identities = 28/114 (24%), Positives = 54/114 (47%), Gaps = 13/114 (11%) Query: 28 INLSVSSVHRRIKHLIE---ANIMGQLKREINFSKLGFTLHILLQVSLSKHDSETFDKFL 84 +NLS+S +HR++ L++ + G+L+ + +K T L S ++ + F + Sbjct: 1 MNLSLSDLHRQVSRLVQQESGDCTGKLRGNVAANK-ETTFQGLTIASGARESEKVFAQ-- 57 Query: 85 SEIEAIPEVTNAFLVTGQSADFILELVARNMDDYSEILLRRIGKIDNV-VALHS 137 + V N L +A + V N+++Y LR +G ++V V+L S Sbjct: 58 ---TVLSHVANVVLTQEDTAKLLQSTVKHNLNNYD---LRSVGNGNSVLVSLRS 105
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 74.3 bits (182), Expect = 8e-19 Identities = 31/198 (15%), Positives = 66/198 (33%), Gaps = 11/198 (5%) Query: 1 MSKKEDIINTALNLFNQIGYNATGVDRIIAESNVAKMTFYKYFPSKENLIMECLQHRNIN 60 ++ I++ AL LF+Q G ++T + I + V + Y +F K +L E + N Sbjct: 10 QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESN 69 Query: 61 IQNSINEQLSLHQDASPLEQ----IHIIFNWYIEWINSETFNGCLFKKAFI--EVSKQYT 114 I + + PL + + + +F K E++ Sbjct: 70 IG-ELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQ 128 Query: 115 SIREPFYEYTKWLTNLLHEKLNQLGI---ENPTPLVHIIISIIDGMIIDGTTDKNLIN-P 170 + R E + L + + I+ I G++ + + Sbjct: 129 AQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLK 188 Query: 171 EKIWKYIEYLINEEIPQP 188 ++ Y+ L+ + P Sbjct: 189 KEARDYVAILLEMYLLCP 206
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 699 bits (1805), Expect = 0.0 Identities = 241/838 (28%), Positives = 392/838 (46%), Gaps = 48/838 (5%) Query: 18 EFDSNFLVGNAQ-KIDIARFKYGNPILPGEYSLDVYINGQWLGKRRMRFTASAPNANAET 76 F+ FL + Q D++RF+ G + PG Y +D+Y+N ++ R + F Sbjct: 48 YFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGYMATRDVTFNTGDSEQGIVP 107 Query: 77 CFTEATLLEYGVKANVLSQHDSTSSLSCKALASWIDSAFYVFDSSRLRIDISLPQVVLEK 136 C T A L G+ +S + + +C L S I A D + R+++++PQ + Sbjct: 108 CLTRAQLASMGLNTASVSGMNLLADDACVPLTSMIHDATAQLDVGQQRLNLTIPQAFMSN 167 Query: 137 NAQGYIDPHLWDRGINAAFLSYNATAYRIVNEQHENS-YAFMGTNLGANLASWQFRHNGQ 195 A+GYI P LWD GINA L+YN + + N NS YA++ G N+ +W+ R N Sbjct: 168 RARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTT 227 Query: 196 WKWQSQSNNS----SYTSTNTYIQKSFPDIHGVVTLGDYFTNSDFIDSLPYRGMNISSDD 251 W + S ++S + NT++++ + +TLGD +T D D + +RG ++SDD Sbjct: 228 WSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDD 287 Query: 252 RMLPNSMLGYAPRVRGYAKTNAKVEIRQQGNLIYQTTVPPGKFEINDLYPTGFGGELQVS 311 MLP+S G+AP + G A+ A+V I+Q G IY +TVPPG F IND+Y G G+LQV+ Sbjct: 288 NMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVT 347 Query: 312 VLESNGVVQKYSIPYASVIEMLRPQMSRYSFTLGQFRDPN-IKLTPWLIQGKYQRGINNY 370 + E++G Q +++PY+SV + R +RYS T G++R N + P Q G+ Sbjct: 348 IKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAG 407 Query: 371 LTTYSAIQGTQQYFSVLLGTAFST-PIGAISFDATHSNTDFSHQPKITGQSYRLSYNKLF 429 T Y Q +Y + G + +GA+S D T +N+ + GQS R YNK Sbjct: 408 WTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSL 467 Query: 430 SPTHTNLTLATYRYSTQNYLKLRDVILIRDLQEQNIDSFSIG--------------KQKS 475 + + TN+ L YRYST Y D R + ++ Sbjct: 468 NESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRG 527 Query: 476 EFQINLNQALPNQWGNFYLVGSWTNYWNQSTTNKQFQLGYSNQFKDLTYSFSAINSETIE 535 + Q+ + Q L YL GS YW S ++QFQ G + F+D+ ++ S S T Sbjct: 528 KLQLTVTQQLGR-TSTLYLSGSHQTYWGTSNVDEQFQAGLNTAFEDINWTLSY--SLTKN 584 Query: 536 AGGRANQDTQYLISLSFPLDFKKSSLNFNSLIS-------------EDSQILSFSG--FT 580 A + D ++++ P S + + + + G Sbjct: 585 AWQKGR-DQMLALNVNIPFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLE 643 Query: 581 GNRLNYGASIS----SQNHGQTNLNINGNYKTNYTTLGASFSYADSYQQEMLNLSGNIVA 636 N L+Y + + NY+ Y +S++D +Q +SG ++A Sbjct: 644 DNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLA 703 Query: 637 HSQGILFGPDQAQTMVLVYAPDATGAQVGNTPGLSINKKGYAVIPYVTPYHMNDISLDPQ 696 H+ G+ G T+VLV AP A A+V N G+ + +GYAV+PY T Y N ++LD Sbjct: 704 HANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTDWRGYAVLPYATEYRENRVALDTN 763 Query: 697 NMSTQVELAESSLRIAPYAGSITKVQFPTKKGYALFISPTTLDGSHLPFAAQVYNQNNEV 756 ++ V+L + + P G+I + +F + G L ++ T + LPF A V +++++ Sbjct: 764 TLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKLLMT-LTHNNKPLPFGAMVTSESSQS 822 Query: 757 IGIVTQGSRIYLRTPLTHDRLYVKWGERNTEKCELEYDITDQIKHNNQSIIMTKAVCK 814 GIV ++YL ++ VKWGE C Y + + + Q + A C+ Sbjct: 823 SGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCVANYQLPPESQ--QQLLTQLSAECR 878
>RTXTOXINC#Gram-negative bacterial RTX toxin-activating protein C signature. Length = 170 Score = 27.6 bits (61), Expect = 0.020 Identities = 9/36 (25%), Positives = 18/36 (50%) Query: 11 LKAGLVDNKKAKKLTKQAHHEQRLGLSNEAEIKANI 46 G +D + A K+ KQ HHE + +++ ++ Sbjct: 133 FHGGKIDKQLANKIFKQYHHELITEVKRKSDFNFSL 168
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 62.3 bits (151), Expect = 2e-14 Identities = 24/112 (21%), Positives = 43/112 (38%), Gaps = 5/112 (4%) Query: 1 MSKKDDIINTALRLFNSYSYNSIGVDRIINESGVAKMTFYKHFPSKEKLIEECLLLRNTL 60 + I++ ALRLF+ +S + I +GV + Y HF K L E L + Sbjct: 10 QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESN 69 Query: 61 LQNSLTSALSKHDELDPLARIKAVFLWYSDWFNSED----FNGCMFQKALEE 108 + L DPL+ ++ + + + +E+ +F K Sbjct: 70 IG-ELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120
>MYCMG045#Hypothetical mycoplasma lipoprotein (MG045) signature. Length = 483 Score = 30.1 bits (67), Expect = 0.017 Identities = 24/92 (26%), Positives = 37/92 (40%), Gaps = 8/92 (8%) Query: 211 FRMPNVAGMMERISDQFSANILLQNPVVDIARKQMSQIGEISSTELSYLKELVLAQLQ-- 268 F N ++ ISD + + + ++ KQMS S E Y E + A L+ Sbjct: 366 FSYVNYVSPLKVISDPSTGIVSSKKNNAEMKSKQMSTDQMTSEKEFDYYTETLKALLEKE 425 Query: 269 DSTALDAAIMSYMSEPKYPDNIPEPDEIEADD 300 DS L+ +E K + I + IE D Sbjct: 426 DSAELNE------NEKKLVETIKKAYTIEKDS 451
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 52.7 bits (126), Expect = 8e-11 Identities = 17/82 (20%), Positives = 37/82 (45%) Query: 3 RQAQFRAREVLIFQVAEQLLLENGEAGMTLDVLAAELDLAKGTLYKHFQSKDELYMLLII 62 + + + I VA +L + G + +L +A + +G +Y HF+ K +L+ + Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 63 RNERMLLEMVQDTEKAFPEHLA 84 +E + E+ + + FP Sbjct: 65 LSESNIGELELEYQAKFPGDPL 86
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 46.8 bits (111), Expect = 3e-09 Identities = 23/55 (41%), Positives = 36/55 (65%), Gaps = 6/55 (10%) Query: 10 QKGFTLIEVMVVIVIMTIMTSLVVLNI-GGVDQKKAMQARELFL-----LDMHKI 58 Q+GFTL+E+MVVIVI+ ++ SLVV N+ G ++ +A + LDM+K+ Sbjct: 7 QRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKL 61
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 37.6 bits (87), Expect = 3e-06 Identities = 17/55 (30%), Positives = 29/55 (52%), Gaps = 3/55 (5%) Query: 1 MKSKGFTLLEVMVALAIFAVAAVALTKVAMQYTQSTSNAILRTKAQFVAMNEIAL 55 M+ +GFTLLE+M+ L + V+A V + + S ++ +T A+F A Sbjct: 1 MRQRGFTLLEMMLILLLMGVSAGM---VLLAFPASRDDSAAQTLARFEAQLRFVQ 52
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 31.8 bits (72), Expect = 0.001 Identities = 12/34 (35%), Positives = 21/34 (61%), Gaps = 1/34 (2%) Query: 40 LRFVNPRSGFTLVELLVSIAIFAIL-SLLGWKVF 72 +R + + GFTL+E++V I I +L SL+ + Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLM 34
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 105 bits (265), Expect = 1e-33 Identities = 34/89 (38%), Positives = 52/89 (58%), Gaps = 1/89 (1%) Query: 7 NKSDLIERIALKNPHLAEPLVEEAVKIMIDQMIEALSTDNRIEIRGFGSFALHHRDPRVG 66 NK DLI ++A L + AV + + L+ ++++ GFG+F + R R G Sbjct: 3 NKQDLIAKVAEAT-ELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKG 61 Query: 67 RNPKTGKSVEVAAKAVPHFKPGKALRDAV 95 RNP+TG+ +++ A VP FK GKAL+DAV Sbjct: 62 RNPQTGEEIKIKASKVPAFKAGKALKDAV 90
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 26.3 bits (58), Expect = 0.032 Identities = 14/88 (15%), Positives = 35/88 (39%), Gaps = 1/88 (1%) Query: 4 ILIALLIVVFGYSLALVLQNPTELSVDLLFTQV-PAMRLGLLLLLTLVLGTVVGLLLGVQ 62 + L +V+ + ++++ + L + L +L L++ VG ++ Sbjct: 141 LKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLLGQILRQLMVICTVGFVVISI 200 Query: 63 VFRVFQKGWEIKRLRKDIDHLRKEQIQS 90 F+ IK L+ D +++E + Sbjct: 201 ADYAFEYYQYIKELKMSKDEIKREYKEM 228
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 31.1 bits (70), Expect = 7e-04 Identities = 14/51 (27%), Positives = 21/51 (41%) Query: 61 IGKDHQAKGYGTKALQMAIDEIAAKGAKRIRTMYKSSNNIAGKLYKEMGFI 111 + KD++ KG GT L AI+ + + N A Y + FI Sbjct: 97 VAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFI 147
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 118 bits (298), Expect = 2e-31 Identities = 77/371 (20%), Positives = 136/371 (36%), Gaps = 76/371 (20%) Query: 22 IGIDLGTTHSLVATVLSGKPKVLNDEKERRLLPSIV-------HYGNDVTHYGEEAKPFI 74 + IDLGT ++L+ + G+ VLN+ PS+V V G +AK + Sbjct: 13 LSIDLGTANTLIY--VKGQGIVLNE-------PSVVAIRQDRAGSPKSVAAVGHDAKQML 63 Query: 75 IADPKNTIVSVKRFMGRSKADIKFQHPYELVGSENEMPAFETRSGRKTPVEISAEILKQL 134 P N I +++ AD ++ +KQ+ Sbjct: 64 GRTPGN-IAAIRPMKDGVIADFF------------------------VTEKMLQHFIKQV 98 Query: 135 KERAESSLQNPVNGAVITVPAYFDEAQRQATRDAAQLAGLNVLRLLNEPTAAAVAYGLDQ 194 S P ++ VP + +R+A R++AQ AG + L+ EP AAA+ GL Sbjct: 99 HSN---SFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPV 155 Query: 195 ETNLATDHNYVIYDLGGGTFDVSILRFSQGVFEVLATGGHTALGGDDLDRLIVKWAKKQL 254 + ++ D+GGGT +V+++ + V +GGD D I+ + ++ Sbjct: 156 SEATGS----MVVDIGGGTTEVAVISLNGVV-----YSSSVRIGGDRFDEAIINYVRRNY 206 Query: 255 NIDTLSDENYAVFIVAARQAKEQLST----QESVQLKL--------LENVLTLDRATFES 302 A + K ++ + E ++++ + TL+ Sbjct: 207 GSLIGEA--------TAERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILE 258 Query: 303 IIQVALDKTISVCKRVLRDAKLEL-SDIQN--VVLVGGSTRSYAVQQAVRNVFNQEPLCT 359 +Q L +S L EL SDI +VL GG + + + + Sbjct: 259 ALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVA 318 Query: 360 INPDEVVAIGA 370 +P VA G Sbjct: 319 EDPLTCVARGG 329
>SECYTRNLCASE#Preprotein translocase SecY subunit signature. Length = 437 Score = 28.2 bits (63), Expect = 0.014 Identities = 10/28 (35%), Positives = 17/28 (60%) Query: 123 IEQLLVQLHIKVDALIEENQQLKAKLNK 150 I QLL + +++AL +E Q AK+ + Sbjct: 88 ILQLLTVVIPRLEALKKEGQAGTAKITQ 115
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 121 bits (305), Expect = 7e-40 Identities = 49/88 (55%), Positives = 68/88 (77%) Query: 2 NKSELIDAIAEKGGVSKTDAGKALDATIASITEALKKGDTVTLVGFGTFSVKERAARTGR 61 NK +LI +AE ++K D+ A+DA ++++ L KG+ V L+GFG F V+ERAAR GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 62 NPKTGEELQIKATKVPSFKAGKGLKDSV 89 NP+TGEE++IKA+KVP+FKAGK LKD+V Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAV 90
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 28.5 bits (64), Expect = 0.005 Identities = 10/36 (27%), Positives = 17/36 (47%), Gaps = 1/36 (2%) Query: 139 IEQVAEQAQAPKEQVYGAIASVLPQVIDSLTPQGDS 174 I +VAE + K+ A+ +V V L +G+ Sbjct: 8 IAKVAEATELTKKDSAAAVDAVFSAVSSYLA-KGEK 42
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 63.3 bits (154), Expect = 3e-13 Identities = 60/249 (24%), Positives = 93/249 (37%), Gaps = 38/249 (15%) Query: 1 MKKLLLAAAVATLSVNAVQAAPTLYGKLNVSINQVDNKNFDG-----KSDVTEVNSNSSR 55 MKK L+A +A L V A A TLYG + + + +G T + S+ Sbjct: 1 MKKSLIALTLAALPV-AAMADVTLYGTIKAGVETSRSVAHNGAQAASVETGTGIVDLGSK 59 Query: 56 IGVKGEEKLTDKLSAVYLAEWAISTDGSGSDTDLSARNRFIGLKTEGVGTLKVGK----- 110 IG KG+E L + L A++ E S +G+D+ R FIGLK G G L+VG+ Sbjct: 60 IGFKGQEDLGNGLKAIWQVEQKASI--AGTDSGWGNRQSFIGLKG-GFGKLRVGRLNSVL 116 Query: 111 YDSYFKTAAGGNQDIFNDDTRLDITNIMYGENRLDNVIGFELDPKLLAGLTFNIMAQTGE 170 D+ D + I E RL I D AGL+ ++ Sbjct: 117 KDTGDINPWDSKSDYLGVNK------IAEPEARL---ISVRYDSPEFAGLSGSVQYA--- 164 Query: 171 STSDSKPGETGKDSKNDSFDSVSTSLGYENKDIGLAIAAAGDFGIKGKYAAYGLKDVYTD 230 ++ + +S Y+N G + G + + + Y Sbjct: 165 ---------LNDNAGRHNSESYHAGFNYKNG--GFFVQYGGAYKRHHQVQENVNIEKY-Q 212 Query: 231 AYRVTGSYD 239 +R+ YD Sbjct: 213 IHRLVSGYD 221
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 98.8 bits (246), Expect = 6e-26 Identities = 32/127 (25%), Positives = 62/127 (48%), Gaps = 1/127 (0%) Query: 15 ILVVEDEYDIGDIIEHYLKREGMRVVRAMNGKQAIEIHAAQPIDLVILDIKMPELSGWEV 74 ILV +D+ I ++ L R G V N AA DLV+ D+ MP+ + +++ Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 75 LNKIRQKAA-TPVIMLTALDQEIDKVMALRIGADDFVVKPFNPNEVVARVQAVLRRTQQN 133 L +I++ PV++++A + + + A GA D++ KPF+ E++ + L ++ Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRR 125 Query: 134 QQTPNRN 140 + Sbjct: 126 PSKLEDD 132
>BICOMPNTOXIN#Staphylococcal bi-component toxin signature. Length = 315 Score = 27.6 bits (61), Expect = 0.021 Identities = 20/62 (32%), Positives = 26/62 (41%), Gaps = 6/62 (9%) Query: 76 KYKNKDEYILWLAGFIERITTGGEAKLPPISKFIPPDFKFNYEEPPKVSSSTQDDGEMII 135 K NKD IL + GFI TT K K + F++N + T D +I Sbjct: 70 KKYNKDALILKMQGFISSRTTYYNYKKTNHVKAMRWPFQYN------IGLKTNDKYVSLI 123 Query: 136 NY 137 NY Sbjct: 124 NY 125
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 39.9 bits (93), Expect = 1e-06 Identities = 25/120 (20%), Positives = 62/120 (51%), Gaps = 7/120 (5%) Query: 50 EVNHKLEQGSSRLWIAIQKGKIVGSVQLSLVRKNNGVHRAEVEKLMVLTAARKQGIATLL 109 +V++ +E+ ++ + +G +++ +N A +E + V RK+G+ T L Sbjct: 56 DVSY-VEEEGKAAFLYYLENNCIGRIKIR----SNWNGYALIEDIAVAKDYRKKGVGTAL 110 Query: 110 LNELEKFSREKGLRLLVLDTREGDVSEL-LYSKIGFVRVGVIPSFALSSNGDYDGTAIYY 168 L++ ++++E L+L+T++ ++S Y+K F +G + + S+ + AI++ Sbjct: 111 LHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF-IIGAVDTMLYSNFPTANEIAIFW 169
>PF05860#haemagglutination activity domain. Length = 117 Score = 66.0 bits (161), Expect = 1e-14 Identities = 19/144 (13%), Positives = 45/144 (31%), Gaps = 29/144 (20%) Query: 74 AGIVADSAANAANRAVIGAGKNSAGTVVPVVNIQTPK-NGISHNIYKQFDVLAEGAVLNN 132 A I D+ + ++ T + + H+ +++F V G N Sbjct: 1 AQITPDTTLPINSNITTEGNT-------RIIERGTQAGSNLFHS-FQEFSVPTSGTAFFN 52 Query: 133 SRQGATTQTVGNVAANPFLATGEARVILNEVNSSAASRFEGNLEVAGQMADVIIANPSGI 192 + + I++ V + S +G + A++ + NP+GI Sbjct: 53 N-------------------PTNIQNIISRVTGGSVSNIDGLIRANAT-ANLFLINPNGI 92 Query: 193 NIKGGGFINANKAIFTTGKPQLNA 216 ++ + + +L Sbjct: 93 IFGQNARLDIGGSFVGSTANRLKF 116
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 83.1 bits (205), Expect = 7e-19 Identities = 76/333 (22%), Positives = 127/333 (38%), Gaps = 30/333 (9%) Query: 136 GGDGNDTLISNTGSDYLYGGAGNDTLVYGGNSNGYTALLGQAGND--TYIIDKVLLSSLS 193 GDG+D + + GS +Y G G+D + Y GY + G + Y + +VL Sbjct: 616 LGDGDDKVFLSAGSANIYAGKGHDVVYYDKTDTGYLTIDGTKATEAGNYTVTRVL----- 670 Query: 194 YVHILDNSTEENTLQLKSVSADEIILKQSNTDIIITFNDSTATIHFGEG-----QLSAIV 248 + L+ V ++ + T+ + T G+ L ++ Sbjct: 671 ---------GGDVKVLQEVVKEQEVSVGKRTEKT-QYRSYEFTHINGKNLTETDNLYSVE 720 Query: 249 FDDGTVWNKAQIEANTIGKLLGNDADDYLQADAEISTIYGLEGNDTIQGGVQNDYLYGGD 308 GT + G D DD ++ + +YG +GNDT+ GG +D LYGGD Sbjct: 721 ELIGTTRADKFFGSKFTDIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGNGDDQLYGGD 780 Query: 309 GNDTLISNTGTDYLYGGAGNDTLIYGGNSNGYTALLGQAGNDTYIVDKA--LLSSWSYVH 366 GND LI G +YL GG G+D GNS L G GND + LL Sbjct: 781 GNDKLIGVAGNNYLNGGDGDDEFQVQGNSLAKNVLFGGKGNDKLYGSEGADLLDGGEGDD 840 Query: 367 ILDNSTEENILQLKSVLADEIILKKSNADIIITFNDSTATIHFGEEQLSSIVFDDGTVWN 426 +L +I + S II + ++ D ++ + + Sbjct: 841 LLKGGYGNDIYRYLSGYGHHIIDDDGGKEDKLSLADIDF------RDVAFKREGNDLIMY 894 Query: 427 KAQIEANTIGKLLGTDADDYLQADAEMKNNYLL 459 K + +IG G ++ + ++ +N+ + Sbjct: 895 KGEGNVLSIGHKNGITFRNWFEKESGDISNHEI 927 Score = 60.0 bits (145), Expect = 1e-11 Identities = 29/60 (48%), Positives = 34/60 (56%) Query: 122 NQMVKGSTGNDYLYGGDGNDTLISNTGSDYLYGGAGNDTLVYGGNSNGYTALLGQAGNDT 181 N + G G+D LYGGDGND LI G++YL GG G+D GNS L G GND Sbjct: 764 NDTLSGGNGDDQLYGGDGNDKLIGVAGNNYLNGGDGDDEFQVQGNSLAKNVLFGGKGNDK 823 Score = 54.2 bits (130), Expect = 7e-10 Identities = 29/59 (49%), Positives = 36/59 (61%), Gaps = 3/59 (5%) Query: 122 NQMVKGSTGNDYLYGGDGNDTLISNTGSDYLYGGAGNDTLVYGGNSNGYTALLGQAGND 180 + +++G+ GND LYG GNDTL G D LYGG GND L+ G N Y L G G+D Sbjct: 746 DDLIEGNDGNDRLYGDKGNDTLSGGNGDDQLYGGDGNDKLI-GVAGNNY--LNGGDGDD 801 Score = 51.1 bits (122), Expect = 7e-09 Identities = 29/65 (44%), Positives = 34/65 (52%), Gaps = 3/65 (4%) Query: 119 TTSNQMVKGSTGNDYLYGGDGNDTLISNTGSDYLYGGAGNDTLVYGGNSNGYTALLGQAG 178 TT GS D +G DG+D + N G+D LYG GNDTL GGN + L G G Sbjct: 725 TTRADKFFGSKFTDIFHGADGDDLIEGNDGNDRLYGDKGNDTL-SGGNGDDQ--LYGGDG 781 Query: 179 NDTYI 183 ND I Sbjct: 782 NDKLI 786 Score = 31.5 bits (71), Expect = 0.008 Identities = 17/77 (22%), Positives = 29/77 (37%), Gaps = 2/77 (2%) Query: 106 IINTASGTYKPTDTTSNQMVKGSTGNDYLYGGDGNDTLI--SNTGSDYLYGGAGNDTLVY 163 ++ G K + ++ G G+D L GG GND S G + G + + Sbjct: 814 VLFGGKGNDKLYGSEGADLLDGGEGDDLLKGGYGNDIYRYLSGYGHHIIDDDGGKEDKLS 873 Query: 164 GGNSNGYTALLGQAGND 180 + + + GND Sbjct: 874 LADIDFRDVAFKREGND 890
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 28.6 bits (63), Expect = 0.022 Identities = 14/31 (45%), Positives = 22/31 (70%), Gaps = 3/31 (9%) Query: 54 VSLEDFGFVNRLSDGRYTLASEVMRLNTIYQ 84 VS E +GF+NRL++ + TL+ + LNT+ Q Sbjct: 586 VSSETYGFLNRLTEAKITLSQQ---LNTLQQ 613
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 57.3 bits (138), Expect = 3e-12 Identities = 32/188 (17%), Positives = 63/188 (33%), Gaps = 14/188 (7%) Query: 41 ERSSKKLQVLHTAIELFNIYGFHNAGVDLIVKKSKIPKATFYNYFHSKQRLIEMCVSFQK 100 E + +L A+ LF+ G + + I K + + + Y +F K L + Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSE 67 Query: 101 SKLKEEVLAIIYSSRYRTSSDKLKEIIVLHVNF---NSLYYLLIKAIFETKQIYPQAYRI 157 S + E L + L+EI++ + LL++ IF + + + Sbjct: 68 SNIGELELEYQ-AKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVV 126 Query: 158 ALEYR----------KWLLKELFDLVFSLETQSLKPSADMVLNLIDGLMFQILSSKSLEE 207 R + LK + + +A ++ I GLM L + + Sbjct: 127 QQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFD 186 Query: 208 RDVVERFF 215 R + Sbjct: 187 LKKEARDY 194
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 46.0 bits (109), Expect = 2e-07 Identities = 38/179 (21%), Positives = 63/179 (35%), Gaps = 5/179 (2%) Query: 33 IICFLIIFTDGIDTAAMGFIAPALAQDWGVDRSQ---LGPVMSAALGGMIIGALVSGPTA 89 I+ + D + + + P L +D G +++ A V G + Sbjct: 8 IVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALS 67 Query: 90 DRFGRKIVLAFSMLVFGGFTLASAYATNLDSLVVLRFLTGIGLGAAMPNATTLFSEYCPT 149 DRFGR+ VL S+ A A L L + R + GI GA A ++ Sbjct: 68 DRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGIT-GATGAVAGAYIADITDG 126 Query: 150 RIRSLLVTCMFCGYNLGMATGGFISSWLIPTYGWHSLFLLGGWSPLILMILVILVLPES 208 R+ M + GM G + + + H+ F + + +LPES Sbjct: 127 DERARHFGFMSACFGFGMVAGPVLGGLM-GGFSPHAPFFAAAALNGLNFLTGCFLLPES 184 Score = 29.0 bits (65), Expect = 0.039 Identities = 33/132 (25%), Positives = 53/132 (40%), Gaps = 11/132 (8%) Query: 289 LPTLMRETGASMERAAFIG---GLFQFGGVVSALFIGWAMDKFNPNRVIAIFYFAAGLFA 345 LP L+R+ S + A G L+ A +G D+F V+ + L Sbjct: 28 LPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLV-----SLAG 82 Query: 346 IAVGQSL-GNSTLLAVLVLCAGIA-INGAQSSMP-ALSARFYPTQCRATGVSWMTGIGRF 402 AV ++ + L VL + +A I GA ++ A A RA +M+ F Sbjct: 83 AAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGF 142 Query: 403 GAVFGAWIGAVL 414 G V G +G ++ Sbjct: 143 GMVAGPVLGGLM 154
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 203 bits (518), Expect = 1e-64 Identities = 81/299 (27%), Positives = 131/299 (43%), Gaps = 25/299 (8%) Query: 101 KVVSIENDTIMKIDATTQSNPDWGLDRIDQRNLPLDSAYSYLQTGSGTTAYIVDTGILST 160 + V I ++K + P G++ I + ++ G G ++DTG + Sbjct: 3 RKVHIIPYQVIKQEQQVNEIP-RGVEMIQ-----APAVWNQ-TRGRGVKVAVLDTGCDAD 55 Query: 161 HQQFSGRVLSGYTAISDGNG----TSDCHGHGTHVAGTVGGS-----TYGVAKNVSLVPI 211 H R++ G D G D +GHGTHVAGT+ + GVA L+ I Sbjct: 56 HPDLKARIIGGRNFTDDDEGDPEIFKDYNGHGTHVAGTIAATENENGVVGVAPEADLLII 115 Query: 212 RILGCDGSGASSNVIAGLDWILKNGKKPAVVNMSLGGEANTS-LDSAVENLFNNGYVMVV 270 ++L GSG +I G+ + ++ +++MSLGG + L AV+ + +++ Sbjct: 116 KVLNKQGSGQYDWIIQGIYYAIEQKVD--IISMSLGGPEDVPELHEAVKKAVASQILVMC 173 Query: 271 AAGNSNTDACS----SSPARVSKAITVAATDSTDTRASYSNYGSCVDIFAPGSQINSSWI 326 AAGN P ++ I+V A + + +SN + VD+ APG I S+ Sbjct: 174 AAGNEGDGDDRTDELGYPGCYNEVISVGAINFDRHASEFSNSNNEVDLVAPGEDILSTVP 233 Query: 327 GSNTATKVLNGTSMATPHVAGVVAEMLQSTPTATPQTISTNLLNQASSNVVKNPSGSPN 385 G AT +GTSMATPHVAG +A + Q + + ++ L SP Sbjct: 234 GGKYAT--FSGTSMATPHVAGALALIKQLANASFERDLTEPELYAQLIKRTIPLGNSPK 290
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 28.7 bits (64), Expect = 0.018 Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 16/84 (19%) Query: 59 VIFIHG-GYWQWCDKSDFAFIVPYVLAKGVQCV---LLEY---DLAPQSKISDIASQINQ 111 VIF+ G G W DK+ + + +G V L+Y P+ D + I++ Sbjct: 54 VIFLSGDGGWATLDKA----VGGILQQQGWPVVGWSSLKYYWKQKDPKDVTQDTLAIIDK 109 Query: 112 ALDFIREQDWKTNEVVLVGHSAGA 135 + ++ T +V+L+G+S GA Sbjct: 110 Y-----QAEFGTQKVILIGYSFGA 128
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 264 bits (675), Expect = 4e-85 Identities = 91/419 (21%), Positives = 187/419 (44%), Gaps = 13/419 (3%) Query: 7 ILTIIVLIYLPVTIDATVMHVATPSLSAALNLTANQLLWVIDIYSLIMAGLILPMGALGD 66 IL + ++ ++ V++V+ P ++ N WV + L + G L D Sbjct: 15 ILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSD 74 Query: 67 RISFKKLLFIGTAVFGVGSLAAAFSPTAYA-LIASRAVLGLGAAMLIPATLSGIRNAFTE 125 ++ K+LL G + GS+ + ++ LI +R + G GAA PA + + + Sbjct: 75 QLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAA-FPALVMVVVARYIP 133 Query: 126 EKQRNFALGLWSTVGGGGAAFGPLVGGFVLEHFHWGAVFLINIPIILVVLVMIVMIIPKQ 185 ++ R A GL ++ G GP +GG + + HW +L+ IP+I ++ V +M + K+ Sbjct: 134 KENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKK 191 Query: 186 QEKTDQPINLGQALILVVAILSLIYSIKSAMYSFSVLTVVMFVIGISTLIHFIRSQKRAT 245 + + ++ +++ V I+ + S SF +++V+ F+I F++ ++ T Sbjct: 192 EVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLI-------FVKHIRKVT 244 Query: 246 TPMIDLELFKHPVISTSIVMAVVSMIALVGFELLLSQELQFVHGFSPLQA-AMFIIPFMI 304 P +D L K+ ++ + + GF ++ ++ VH S + ++ I P + Sbjct: 245 DPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTM 304 Query: 305 AISLGGPLAGICLNKWGLRLVSTVGILISGFSLWGLAQLNFSTDHFLAWTCMVFLGFSIE 364 ++ + G + GI +++ G V +G+ S + L +T F+ + LG Sbjct: 305 SVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSF 364 Query: 365 IALLASTAAIMSSVPPQKASAAGAIEGMAYELGAGLGVAIFGLMLSWFYSRSIILPEQL 423 + ST S + + + ++ L G G+AI G +LS +LP ++ Sbjct: 365 TKTVISTIVSSSLKQQEAGAGMSLLNFTSF-LSEGTGIAIVGGLLSIPLLDQRLLPMEV 422
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 55.0 bits (132), Expect = 9e-12 Identities = 25/169 (14%), Positives = 59/169 (34%), Gaps = 12/169 (7%) Query: 5 NRDQRREMILQAAMQVALAEGFTAMTVRRIATEAQTSTGQVHHHFSSASHLKAEAFLKLM 64 + R+ IL A+++ +G ++ ++ IA A + G ++ HF S L +E + Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSE 67 Query: 65 EQLDEIEQTL----------QTTSQFQRLFILLGAENIDKLQPYLRLWNEAELLIEQDIE 114 + E+E + E +L + + + + Sbjct: 68 SNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRL--LMEIIFHKCEFVGEMAV 125 Query: 115 IQKAYNLAMQSWHETIVQAIECGQKEGEFKNRSNSTDIAWRLIAFVCGL 163 +Q+A ++ I Q ++ + + A + ++ GL Sbjct: 126 VQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGL 174
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 75.5 bits (185), Expect = 2e-17 Identities = 65/262 (24%), Positives = 114/262 (43%), Gaps = 23/262 (8%) Query: 220 AKPLAGKTALVTGASRGIGEAIAHVLARDGAHVICLD-VPQQQADLDRVAADIGGSTLAI 278 AK + GK A +TGA++GIGEA+A LA GAH+ +D P++ + A Sbjct: 3 AKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAF 62 Query: 279 DITAADAG---EKIKAAAAKQGGLDIIVHNAGITRDKTLANMKPELWDLVININ----LS 331 D+ E + G +DI+V+ AG+ R + ++ E W+ ++N + Sbjct: 63 PADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 332 AAERVNDYLLENDGLNANGRIVCVSSISGIAGNLGQTNYAASKAGVIGLVKFTA-PILKN 390 A+ V+ Y+++ G IV V S YA+SKA + K + + Sbjct: 123 ASRSVSKYMMDRRS----GSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEY 178 Query: 391 GITINAVAPGFIETQMTAAIPFAIREAGRRMNS----------MQQGGLPVDVAETIAWF 440 I N V+PG ET M ++ A + + +++ P D+A+ + + Sbjct: 179 NIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFL 238 Query: 441 ASTASTGVNGNVVRVCGQSLLG 462 S + + + + V G + LG Sbjct: 239 VSGQAGHITMHNLCVDGGATLG 260
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 34.5 bits (79), Expect = 9e-05 Identities = 26/135 (19%), Positives = 57/135 (42%), Gaps = 13/135 (9%) Query: 7 DEQAEDIEAIEKLTKAAFQNAEHTSHTEHFIVNSLRAHGQLTISLVAIEDESIIGHIA-- 64 ++ E ++ AF+N T E F + + + + +E+E + Sbjct: 14 NKPNEPFVVFGRMI-PAFENGVWTYTEERFSKPYFKQYEDDDMDVSYVEEEGKAAFLYYL 72 Query: 65 ----ISPVEISSGEIGWYGLGPISVHPNKQGCGVGSLLINKSLEKLKQLGAQGCVL---- 116 I ++I S G+ + I+V + + GVG+ L++K++E K+ G +L Sbjct: 73 ENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQD 132 Query: 117 --LGDPNYYSRFGFK 129 + ++Y++ F Sbjct: 133 INISACHFYAKHHFI 147
>adhesinb#Adhesin B signature. Length = 310 Score = 30.6 bits (69), Expect = 0.001 Identities = 17/69 (24%), Positives = 26/69 (37%), Gaps = 11/69 (15%) Query: 1 MKKILLTALAGFALLGSSAVMAKPDAALLNEATKNVVTVAKVKTLADESGVTLTGTIVKH 60 MKK L A +G +A ++ + + NVV ++ I K+ Sbjct: 1 MKKCRFLVLLLLAFVGLAACSSQKSSTETGSSKLNVVAT-----------NSIIADITKN 49 Query: 61 IAGDHFELK 69 IAGD L Sbjct: 50 IAGDKINLH 58
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 28.2 bits (63), Expect = 0.044 Identities = 17/48 (35%), Positives = 25/48 (52%), Gaps = 1/48 (2%) Query: 232 FTQCSAPEHLTILSADHGLGPLEPMEVAVYRSRASLESKAV-DHLYDL 278 +T + EHL +L H L P P ++A SR E+ A D L+D+ Sbjct: 306 YTVNTLAEHLDMLMVCHHLSPTIPEDIAFAESRIRKETIAAEDILHDI 353
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 55.8 bits (134), Expect = 2e-11 Identities = 37/163 (22%), Positives = 69/163 (42%), Gaps = 10/163 (6%) Query: 18 VGASQGIGAAVCRLFAKEGLKVYVAGRTFQKIEAVAAQIHSNGGDAVAFRLDAEDIHQVQ 77 GA+QGIG AV R A +G + +K+E V + + + A AF D D + Sbjct: 14 TGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSAAID 73 Query: 78 ALFDTITSQNERITAVIHNVGGNMPSIFLRSPL-SFFTQMWQSTF----LSAYLVSQSCL 132 + I + I ++ N+ + + S + W++TF + S+S Sbjct: 74 EITARIEREMGPIDILV-----NVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 133 KIFKDQNHGTLIFTGASASLRGKPFFAAFTMGKSALRAYALNL 175 K D+ G+++ G++ + + AA+ K+A + L Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCL 171
>2FE2SRDCTASE#Ferric iron reductase signature. Length = 262 Score = 31.2 bits (70), Expect = 0.003 Identities = 11/35 (31%), Positives = 17/35 (48%), Gaps = 3/35 (8%) Query: 64 STRIARYLDEAFPDTPRLYPEDPNQKALAELWEDW 98 S+ +A Y D + + P + E+ K L LW W Sbjct: 67 SSLLAVYSDHIYRNQPMMIREN---KPLISLWAQW 98
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 55.7 bits (134), Expect = 1e-12 Identities = 22/92 (23%), Positives = 42/92 (45%), Gaps = 5/92 (5%) Query: 43 ENRESVFFIHIKDDKITGFILLYLGFSSVACSTYYILDDVYVTPVFRRQGSAKQLIDTAI 102 E F++ ++ G I + + Y +++D+ V +R++G L+ AI Sbjct: 61 EEEGKAAFLYYLENNCIGRIKI-----RSNWNGYALIEDIAVAKDYRKKGVGTALLHKAI 115 Query: 103 LFAKQENALRISLETQSNNHESHRLYEQMGFI 134 +AK+ + + LETQ N + Y + FI Sbjct: 116 EWAKENHFCGLMLETQDINISACHFYAKHHFI 147
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 49.1 bits (117), Expect = 2e-08 Identities = 28/155 (18%), Positives = 53/155 (34%), Gaps = 18/155 (11%) Query: 74 IRPQVSGKLIAVHFKDGSLVKKGDLLFTIDPRPFEAELNRAQAQLASAEAQVTYTGSNLS 133 I+P + + + K+G V+KGD+L + EA+ + Q+ L A + Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARL-------EQT 151 Query: 134 RIQRLIQSNAVSRQELDLAQNDARSASANLQAARAAVQSARLNLEYTRITAPVSGRISRA 193 R Q L +S EL+ Q +L + + + Sbjct: 152 RYQILSRS-----IELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFST------WQN 200 Query: 194 EVTVGNVVSAGNGAQVLTSLVSVSRLYASFDVDEQ 228 + + A+ LT L ++R V++ Sbjct: 201 QKYQKELNLDKKRAERLTVLARINRYENLSRVEKS 235 Score = 49.1 bits (117), Expect = 2e-08 Identities = 19/99 (19%), Positives = 38/99 (38%), Gaps = 3/99 (3%) Query: 108 EAELNRAQAQLASAEAQVTYTGSNLSRIQRLIQSNAVSRQELDLAQNDARSASANLQAAR 167 E + A +L ++Q+ S + + Q + L + R + N+ Sbjct: 258 ENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKL--RQTTDNIGLLT 315 Query: 168 AAVQSARLNLEYTRITAPVSGRISRAEV-TVGNVVSAGN 205 + + + I APVS ++ + +V T G VV+ Sbjct: 316 LELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAE 354
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 59.2 bits (143), Expect = 4e-12 Identities = 36/183 (19%), Positives = 75/183 (40%), Gaps = 20/183 (10%) Query: 56 PQRVAVLDMNEADFLDQLNVPIMGMP--KDYVPHFLEKYKKDAQIQDLGAIVQPNMERLY 113 P R+ L+ + L L + G+ +Y E D+ I D+G +PN+E L Sbjct: 35 PNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSEPPLPDSVI-DVGLRTEPNLELLT 93 Query: 114 ALKPDLILMTPLHVNQYQELSKIAPTIHYDINFNNSESNHIGLVKDHMMTLGKIFNKEDL 173 +KP ++ + + + L++IAP ++ + + + + + + + N + Sbjct: 94 EMKPSFMVWSAGYGPSPEMLARIAPGRGFNFSDG---KQPLAMARKSLTEMADLLNLQSA 150 Query: 174 ARQKVSELDEQVKQVQAVTANRPERALV-----------VLHNNGAFSNFGIQSRYGFIF 222 A +++ ++ ++ ++ R R L+ V N F I YG I Sbjct: 151 AETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQE--ILDEYG-IP 207 Query: 223 NAF 225 NA+ Sbjct: 208 NAW 210
>CLENTEROTOXN#Clostridium enterotoxin signature. Length = 319 Score = 30.0 bits (67), Expect = 0.026 Identities = 22/108 (20%), Positives = 39/108 (36%), Gaps = 11/108 (10%) Query: 96 IIWLPVDMDSPPSRLN---YLLTNSRADVVVSDSSIAGVQNLNINEILSATTEFEPSFNA 152 IWL ++ + T R + V + I I ++ +AT + Sbjct: 160 GIWLSKTSADSLGNIDQGSLIETGERCVLTVPSTDIEK----EILDLAAATERL--NLTD 213 Query: 153 EINRLPAYYLYTSGSTGTPKCVVLNNQATENTIQQTISEWKITADDVI 200 +N PA LY S+ + N TI T +++I A ++ Sbjct: 214 ALNSNPAGNLYDWRSSNSYPWTQKLN--LHLTITATGQKYRILASKIV 259
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 47.7 bits (113), Expect = 4e-09 Identities = 23/163 (14%), Positives = 46/163 (28%), Gaps = 8/163 (4%) Query: 12 QIINTSIHLFHHHGFHTVGIDRIVKESHTPKATFYNYFHSKERFIEICLIVQKERLKEKV 71 I++ ++ LF G + + I K + + Y +F K + + + E Sbjct: 15 HILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELE 74 Query: 72 DVIVEYDQSTNGKDKLKKLY-FLHSDVEGPYYLLFKAIFETKLIYPKAYITAVRYRTWLI 130 + L L S V L I K + + + L Sbjct: 75 LEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRNLC 134 Query: 131 NEIYSQLRTLKNDA-------TFQDAKLFLYMIEGAIIQLLSS 166 E Y ++ + ++ G I L+ + Sbjct: 135 LESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMEN 177
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 32.4 bits (73), Expect = 0.007 Identities = 29/156 (18%), Positives = 55/156 (35%), Gaps = 20/156 (12%) Query: 211 EINMFGSAP-FKNYTFMTMATGNSYGGLEHCNSTSLITPRDDLPKSNEPTEPSKDYQRFL 269 + ++ S +K + + ++ GG+ N + T P + Sbjct: 448 TVVIYNSPEEYKLNRIINGFSTDN-GGIYIENIGTFFTYE---------RTPEESIYTLE 497 Query: 270 GLCSHEYFHSWLVKFIRPENFANYNLHQEGYTSLLWIFEGFTSYYDDLILLRSGVISQKS 329 L HE+ H +++ P + +QEG L W EG ++ G+ +KS Sbjct: 498 ELFRHEFTHYLQGRYVVPGMWGQGEFYQEGV--LTWYEEGTAEFFAGS-TRTDGIKPRKS 554 Query: 330 YLDLLKAQIDRYLQNPGRFVQTVAESSFDAWIKFYR 365 L Y +N + V + + +W FY Sbjct: 555 VTQGLA-----YDRNNRMSLYGVLHAKYGSW-DFYN 584
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 42.9 bits (101), Expect = 1e-06 Identities = 31/162 (19%), Positives = 59/162 (36%), Gaps = 13/162 (8%) Query: 3 FFLSLFTLFFSIFCTTLTNAALLNIAPESVEAAAWTI----VDTQSGQIIAEHNSHVQRA 58 L + +L ++ + L S + + +D SG+ + + + Sbjct: 4 IRLCIISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFP 63 Query: 59 PASLTKMMVAYIALKEIKAGKLKKEEIITATPVVSVVQWD-ESQMYLKAGEQISVDQLLA 117 S K+++ L + AG + E I +V + S+ +L G ++V +L A Sbjct: 64 MMSTFKVVLCGAVLARVDAGDEQLERKIHYRQ-QDLVDYSPVSEKHLADG--MTVGELCA 120 Query: 118 GLIVMSANDAAVTLAEKISGDVPRFVQRMNQEAQALGMKDTH 159 I MS N AA L + G + + +G T Sbjct: 121 AAITMSDNSAANLLLATVGG-----PAGLTAFLRQIGDNVTR 157
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 26.9 bits (59), Expect = 0.037 Identities = 19/67 (28%), Positives = 28/67 (41%), Gaps = 4/67 (5%) Query: 12 ANNHVVSFHYKLTNAEGETLDQSQ--GEPLAYLHGAGNIIPGLENALTGKTVGEKFTVNV 69 + V+ Y T +G D ++ G+P + +IPG AL G + V V Sbjct: 142 GKSDTVTVEYTGTLIDGTVFDSTEKAGKPATF--QVSQVIPGWTEALQLMPAGSTWEVFV 199 Query: 70 PAAEGYG 76 PA YG Sbjct: 200 PADLAYG 206
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 47.1 bits (112), Expect = 5e-08 Identities = 59/301 (19%), Positives = 102/301 (33%), Gaps = 78/301 (25%) Query: 15 KRIVVKIGSSLLTANGQGLDLD----AISHWAKQIADLHNAGHEIILVSSGAVAEGMV-- 68 KR+V+ +G + L GQ + + A+QIA++ G+E+++ G + Sbjct: 3 KRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSLLL 62 Query: 69 RMKLASRPTDLPS--LQACAAIGQMGLIHTW-----SSVLENHGIR------TAQVLLTH 115 M +P+ + A+ Q G I + L G+ Q ++ Sbjct: 63 HMDAGQATYGIPAQPMDVAGAMSQ-GWIGYMIQQALKNELRKRGMEKKVVTIITQTIVDK 121 Query: 116 DDLADR----------------------------------RRYLNS--------CDALQN 133 +D A + RR + S + ++ Sbjct: 122 NDPAFQNPTKPVGPFYDEETAKRLAREKGWIVKEDSGRGWRRVVPSPDPKGHVEAETIKK 181 Query: 134 LIDWRVI---------PVINENDTVSTDEIRFGDNDTLAAMVAGQVHAELLIILTDQQGM 184 L++ VI PVI E+ + E D D +A +V+A++ +ILTD G Sbjct: 182 LVERGVIVIASGGGGVPVILEDGEIKGVEAVI-DKDLAGEKLAEEVNADIFMILTDVNGA 240 Query: 185 FDSDPRHNPDAKLLSTVRAMDDDLFDMAGGGGVLGRGGMVTKVRAA-RLAAKSGCPTLIA 243 + L V+ + + G G M KV AA R G +IA Sbjct: 241 ALY--YGTEKEQWLREVKVEELRKYYEEGH---FKAGSMGPKVLAAIRFIEWGGERAIIA 295 Query: 244 S 244 Sbjct: 296 H 296
>PilS_PF08805#PilS N terminal Length = 185 Score = 28.4 bits (63), Expect = 0.048 Identities = 13/86 (15%), Positives = 24/86 (27%), Gaps = 1/86 (1%) Query: 217 GAILNSADHLRIQVNGKQVHGSTPWLGRDPIYASAQMINNLQSLISRRTDLTQGMGVVSI 276 + ++ Q N V + L Y + I L + +D+ S Sbjct: 52 SMVQSNIQSSNEQNNVLTVIANMKSLKFQGRYTDSNYIKTLYAQGLLPSDMIADTTGASA 111 Query: 277 GNIQGGTAGNVIPEQVNMIGTIRSNN 302 N GG+ + + N Sbjct: 112 KNPWGGSV-TITTSSDKYSFNVVEAN 136
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 68.6 bits (167), Expect = 1e-14 Identities = 41/315 (13%), Positives = 102/315 (32%), Gaps = 15/315 (4%) Query: 49 LVKPEDLPPPLAKEIEQETTATNEAKEVLTPIVDETLPQNLPTTPPP---PTAQQLAAQQ 105 V ++ P + + + +N + P PP P+ + Sbjct: 991 TVDTTNITTPNNIQADVPSVPSNNEEI--------ARVDEAPVPPPAPATPSETTETVAE 1042 Query: 106 QKAEQAQQAKLAEQKRKAEEAAKMKQAAEQQRKEEIQKQQAKAKSEAEQKRKAEQTAKAQ 165 ++++ + EQ A + A E + + Q + + ++ + T + Sbjct: 1043 NSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKE 1102 Query: 166 ADTKAKQEQS--EARKAAEDAKRKAEADAKLKREAQKAENAKLQAQQEAKRKAEADAKAK 223 T K+E++ E K E K ++ K ++ A+ + + + + +++ Sbjct: 1103 TATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIK-EPQSQ 1161 Query: 224 QQKANDDAKRKAEADAKAKQQKAADDAKRKAEAAAKAKQQKSADDAKRKAEADAKAKQQK 283 D + E + +Q + + + + + +++ K + Sbjct: 1162 TNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKN 1221 Query: 284 ANDEAKRKAEADAKAKQQKADDAKRKADADAKAKQQKAA-DDAKRKAEADAKAKQKAADD 342 + + R + + ++D A D + A DA+ KA+ A KA Sbjct: 1222 RHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQ 1281 Query: 343 AKRKAEAEAEAKAAS 357 + E E + Sbjct: 1282 HISQLEMNNEGQYNV 1296 Score = 67.0 bits (163), Expect = 5e-14 Identities = 32/277 (11%), Positives = 83/277 (29%), Gaps = 3/277 (1%) Query: 92 TPPPPTAQQLAAQQQKAEQAQQAKLAEQKRKAEEAAKMKQAAEQQRKEEIQKQQAKAKSE 151 T T + A + + A + + E KQ++K + Sbjct: 994 TTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEK 1053 Query: 152 AEQKRKAEQTAKAQADTKAKQEQSEARKAAEDAKRKAEADAKLKREAQKAENAKLQAQQE 211 EQ + +AK + E A+ +E K + + E A ++ +++ Sbjct: 1054 NEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSE--TKETQTTETKETATVEKEEK 1111 Query: 212 AKRKAEADAKAKQQKANDDAKRKAEADAKAKQQKAADDAKRKAEAAAKAKQQKSADDAKR 271 AK + E + + + K++ + + + A ++ +++ +AD + Sbjct: 1112 AKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQP 1171 Query: 272 KAEADAKAKQQKANDEAKRKAEADAKAKQQKADDAKRKADADAKAKQQKAADDAKRKAEA 331 E + +Q + + + + + + K ++ Sbjct: 1172 AKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVP 1231 Query: 332 DAKAKQKAADDAKRKAEAEAEAKAASAQKAQEEAAQK 368 + R A + + + +A K Sbjct: 1232 -HNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAK 1267 Score = 59.7 bits (144), Expect = 1e-11 Identities = 33/270 (12%), Positives = 90/270 (33%), Gaps = 7/270 (2%) Query: 107 KAEQAQQAKLAEQ-----KRKAEEAAKMKQAAEQQRKEEIQKQQAKAKSEAEQKRKAEQT 161 + E+ Q +A+ + E R +E + +E + Sbjct: 984 EVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAEN 1043 Query: 162 AKAQADTKAKQEQSEARKAAEDAKRKAEADAKLKREAQKAENAKLQAQQEAKRKAEADAK 221 +K ++ T K EQ A++ + EA + +K Q E A+ ++ + + E Sbjct: 1044 SKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKET 1103 Query: 222 AKQQKANDDAKRKAEADAKAKQQKAADDAKRKAEAAAKAKQQKSADDAKRKAEADAKAKQ 281 A +K + AK + E + + + K++ + + + + ++ + +++ Sbjct: 1104 ATVEKE-EKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQT 1162 Query: 282 QKANDEAKRKAEADAKAKQQKADDA-KRKADADAKAKQQKAADDAKRKAEADAKAKQKAA 340 D + E + +Q + ++ + + + +++ K K Sbjct: 1163 NTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNR 1222 Query: 341 DDAKRKAEAEAEAKAASAQKAQEEAAQKKA 370 ++ A ++ + A Sbjct: 1223 HRRSVRSVPHNVEPATTSSNDRSTVALCDL 1252 Score = 55.1 bits (132), Expect = 3e-10 Identities = 36/264 (13%), Positives = 91/264 (34%), Gaps = 18/264 (6%) Query: 122 KAEEAAKMKQAAEQQRKEEIQKQQAKAKSEAEQKRKAEQTAKAQADTKAKQEQSEARKAA 181 + E+ + IQ S E+ + ++ E +E A Sbjct: 984 EVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTE--TVA 1041 Query: 182 EDAKRKAEADAKLKREAQKAENAKLQAQQEAKRKAEADAKAKQQKANDDAKRKAEADAKA 241 E++K++++ K +++A + + +EAK +A+ + N+ A+ +E + Sbjct: 1042 ENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQT-----NEVAQSGSET-KET 1095 Query: 242 KQQKAADDAKRKAEAAAKAKQQKSADDAKRKAEADAKAKQQKANDEAKRKAEADAKAKQQ 301 + + + A + E AK + +K+ + K ++ KQ ++E + Sbjct: 1096 QTTETKETATVEKEEKAKVETEKTQEVPKVTSQV--SPKQ--------EQSETVQPQAEP 1145 Query: 302 KADDAKRKADADAKAKQQKAADDAKRKAEADAKAKQKAADDAKRKAEAEAEAKAASAQKA 361 ++ + +++ AD + E + +Q + + A Sbjct: 1146 ARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPA 1205 Query: 362 QEEAAQKKAEAKKVASSARRDFST 385 + + K + RR + Sbjct: 1206 TTQPTVNSESSNKPKNRHRRSVRS 1229 Score = 53.5 bits (128), Expect = 1e-09 Identities = 30/206 (14%), Positives = 74/206 (35%), Gaps = 5/206 (2%) Query: 187 KAEADAKLKREAQKAENAKLQAQQEAKRKAEADAKAKQQKANDDAKRKAEADAKAKQQKA 246 + E + +QA + A+ +A A A + Sbjct: 984 EVEKRNQTVDTTNITTPNNIQADVPSVPSNNE-EIARVDEAPV--PPPAPATPSETTETV 1040 Query: 247 ADDAKRKAEAAAKAKQQKSADDAKRKAEADAKAKQQKANDEAKRKAEADAKAKQQKADDA 306 A+++K++++ K +Q + A+ + A KAN + A++ ++ K+ + + Sbjct: 1041 AENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTET 1100 Query: 307 KRKADADAKAKQQKAADDAKRKAE--ADAKAKQKAADDAKRKAEAEAEAKAASAQKAQEE 364 K A + + K + + + + + KQ+ ++ + +AE E K + Sbjct: 1101 KETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQS 1160 Query: 365 AAQKKAEAKKVASSARRDFSTLLGRS 390 A+ ++ A + + S Sbjct: 1161 QTNTTADTEQPAKETSSNVEQPVTES 1186
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 29.7 bits (66), Expect = 0.029 Identities = 17/110 (15%), Positives = 42/110 (38%), Gaps = 11/110 (10%) Query: 173 AERYTLQIADTDGEQPKTVLSSRDPILSPAWTPDAKKIAYVSFETKRPAIYLQDLSTGTR 232 A R+ + + E PK +++ +D + ++++ V +E + D+ + + Sbjct: 138 ASRF---VFEKKRETPKLIINIKD------YAINSEQSKEVYYEIGK--GISLDIISKDK 186 Query: 233 EVLTSFRGLNGAPSFSPDGQSMLFTASMNGNPEIYQMDLSTRQVKRMTND 282 + F L + S D +LF+ E+ + +K + Sbjct: 187 SLDPEFLNLIKSLSDDSDSSDLLFSQKFKEKLELNNKSIDINFIKENLTE 236
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 108 bits (272), Expect = 6e-31 Identities = 32/117 (27%), Positives = 52/117 (44%), Gaps = 11/117 (9%) Query: 76 VHFDYDSSDLSTEDYQTLQAHAQFLIAN--ANSKVALTGHTDERGTREYNMALGERRAKA 133 V F+++ + L E L L + V + G+TD G+ YN L ERRA++ Sbjct: 221 VLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQS 280 Query: 134 VQSYLITNGVNPQQLEAVSYGKEAPVNAGHDESA---------WKENRRVEINYEAV 181 V YLI+ G+ ++ A G+ PV ++ +RRVEI + + Sbjct: 281 VVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKGI 337
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 82.8 bits (204), Expect = 6e-22 Identities = 39/185 (21%), Positives = 84/185 (45%), Gaps = 11/185 (5%) Query: 1 MSVREQKMAETRKKLIEVARRAFAEYGYADTSMDKLTAEAGLTRGALYHHFGDKRGLFAA 60 +Q+ ETR+ +++VA R F++ G + TS+ ++ AG+TRGA+Y HF DK LF+ Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 61 VVDQIDSQMAKYAQQHLEQ-PDDLWEGLLLEGQTYIQNALNPEFQRIVLRDGPAVLGDPA 119 + + +S + + ++ + P D L +++ + E +R+++ Sbjct: 62 IWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVG 121 Query: 120 HWPSQNR-----CLQSTRKCVEQLLTAEQIKI----VDPEAAAVLLNGAAMNAAL-WVAS 169 + CL+S + + L + K+ + AA+++ G W+ + Sbjct: 122 EMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFA 181 Query: 170 SEYPE 174 + + Sbjct: 182 PQSFD 186
>INTIMIN#Intimin signature. Length = 939 Score = 39.3 bits (91), Expect = 2e-04 Identities = 56/323 (17%), Positives = 94/323 (29%), Gaps = 30/323 (9%) Query: 353 NGVTYTATVDSAAGTWT----VNVPGSGLEADADKTIDATVTFTDAAGNSSTVNDTQTYT 408 N V T TV S + A AD T T T T + N ++ Sbjct: 540 NNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKNGVAQANVPVSFN 599 Query: 409 LDTSVPTVALEDVSTNDNTPALTGTVSDPTATVVVTI------DGVDYPAVNNGDGT--- 459 + + ++ +TN + A SD VVV+ ++ AV D T Sbjct: 600 IVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQTKAS 659 Query: 460 -WTLADNTLPTLTDGPHTVTVTATDAAGNKGTDTGVVTVDTAAPNTAGVNFAVDPVTSDN 518 + + + +G +T T G+K V+ T + +D Sbjct: 660 ITEIKADKTTAVANGQDAITYTVKVMKGDK-----PVSNQEVTFTTTLGKLSNSTEKTD- 713 Query: 519 VINASEAASNVTITGVLKNVPSDAATTAVTVVINGVTYNATVNSAAGTWTVSVPGSGLVA 578 + + P + +A + V + Sbjct: 714 -------TNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGT 766 Query: 579 DTDKTIDAKVTFTDAAGNSSTVNDTQTYTLDTAAPAAPVIDPVNGTDPITGTAEPGSTVT 638 + V N YT +A PA +D +G +T + +T++ Sbjct: 767 GVKGKL-PTVWLQYGQVNLKASGGNGKYTWRSANPAIASVDASSGQ--VTLKEKGTTTIS 823 Query: 639 VTYPDGSTASVVAGPDGSWSVPN 661 V D TA+ S VPN Sbjct: 824 VISSDNQTATYTIATPNSLIVPN 846 Score = 38.5 bits (89), Expect = 4e-04 Identities = 49/249 (19%), Positives = 84/249 (33%), Gaps = 38/249 (15%) Query: 803 NDPTATVVVNVDGVDYPAVNNGDGTWTLADNTLPALTDGPHTVTVTATDPAGNVATDTAT 862 N+ T+ V + V + G + A DG +T TAT VA Sbjct: 540 NNVLLTITV----LSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKNGVAQANVP 595 Query: 863 VTIDTVPADLIGAITIPEDLNGDGILNADELGTDGTFNAQVALGPDAIDGTVVNVNGTNY 922 V+ + V +G +L+A+ T+G+ A V L D VV+ Sbjct: 596 VSFNIV--------------SGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEM 641 Query: 923 TVTAADLANGFI---TATLDATAADPVT----GQIVIHAEAVDAQGNVDVADADVTL--- 972 T A F+ A++ AD T GQ I +G+ V++ +VT Sbjct: 642 TSALNANAVIFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKGDKPVSNQEVTFTTT 701 Query: 973 ------TIDTTPQDLITAITVPEDLNGDGILNAAELGTDGTFNAQVAL---GPDAIDGTV 1023 + + T + +T+ G ++ +A + + ID Sbjct: 702 LGKLSNSTEKTDTNGYAKVTLTSTTPGKSLV-SARVSDVAVDVKAPEVEFFTTLTIDDGN 760 Query: 1024 VNVNGTNYT 1032 + + GT Sbjct: 761 IEIVGTGVK 769
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 29.8 bits (67), Expect = 0.022 Identities = 8/26 (30%), Positives = 11/26 (42%) Query: 179 YKYTVGQPFIYPRNDLSYAENFLHMM 204 Y T G+P PR S + +M Sbjct: 610 YHVTTGEPVCQPRRPNSRIDKVRYMF 635
>TACYTOLYSIN#Bacterial thiol-activated pore-forming cytolysin signature. Length = 574 Score = 29.2 bits (65), Expect = 0.025 Identities = 9/35 (25%), Positives = 17/35 (48%), Gaps = 1/35 (2%) Query: 88 EDWKIVIQYASTCKLVDNRRIVLWGTSLSGGYALS 122 E W+ VI KL + + G++LS +++ Sbjct: 539 EWWRKVID-ERDVKLSKEINVNISGSTLSPYGSIT 572
>INTIMIN#Intimin signature. Length = 939 Score = 36.6 bits (84), Expect = 3e-04 Identities = 38/158 (24%), Positives = 57/158 (36%), Gaps = 5/158 (3%) Query: 150 NNGTLTQEQTVTVTGSNSTVEADTTSIVLFDATKTSLNVRGDQTTVTLTAVDANGATLAN 209 NG + +T+T ++ D + F A KTS G + V NG AN Sbjct: 534 RNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKNGVAQAN 593 Query: 210 QAITLKVRNSVLNGVKFTPNSTQTDANGQITYTL-SFSENQRTSSYSAAQFVTDDLVLEA 268 ++ N V + NS T+ +G+ T TL S Q S A+ + Sbjct: 594 VPVSF---NIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAV 650 Query: 269 NFGQSTKIYTYKLDVVNSDVPVAVGAIAVAYNPTTMED 306 F TK ++ VA G A+ Y M+ Sbjct: 651 IFVDQTKASITEIKADK-TTAVANGQDAITYTVKVMKG 687
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 29.1 bits (65), Expect = 0.015 Identities = 14/74 (18%), Positives = 24/74 (32%), Gaps = 18/74 (24%) Query: 87 LAIRQKSTEIDSVEDI------------RLPLQSGTVFARHYH------PSPNKKLPLIV 128 + IR +EDI L +A+ H + + + Sbjct: 80 IKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACH 139 Query: 129 FYHGGGFVVGGLDT 142 FY F++G +DT Sbjct: 140 FYAKHHFIIGAVDT 153
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 141 bits (356), Expect = 3e-39 Identities = 79/380 (20%), Positives = 141/380 (37%), Gaps = 69/380 (18%) Query: 5 IGIDLGTTNSCVAVLEGDKVKVIENAEGARTTPSIIAYKDGEILVGQSAKRQAVTNPKNT 64 + IDLGT N+ + V V + R + VG AK+ P N Sbjct: 13 LSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRA--GSPKSVAAVGHDAKQMLGRTPGN- 69 Query: 65 LFAIKRLIGRRYEDQAVQKDIGLVPYKIIKADNGDAWVEVNDKKLAPQQVSAEILKK-MK 123 + AI+ P K D +A V+ ++L+ +K Sbjct: 70 IAAIR-------------------PMK--------------DGVIADFFVTEKMLQHFIK 96 Query: 124 KTAEDYLGETVTEAVITVPAYFNDAQRQATKDAGKIAGLDVKRIINEPTAAALAFGMDKK 183 + + ++ VP +R+A +++ + AG +I EP AAA+ G+ Sbjct: 97 QVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVS 156 Query: 184 EGDRKVAVYDLGGGTFDVSIIEIADLDGDQQIEVLSTNGDTFLGGEDFDNALIEFLVEEF 243 E V D+GGGT +V++I + + + +GG+ FD A+I ++ + Sbjct: 157 E-ATGSMVVDIGGGTTEVAVISLNG---------VVYSSSVRIGGDRFDEAIINYVRRNY 206 Query: 244 KKEQSVNLKNDPLALQRLKEAAEKAKIELSSS----NATEINLPYITADATGPKHLVINV 299 + AE+ K E+ S+ EI + P+ +N Sbjct: 207 GSLIG-------------EATAERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLN- 252 Query: 300 TRAKLEGLVADLVARTIEPCKIALKD-AGLSTSDISD--VILVGGQSRMPLVQQKVQEFF 356 + LE L + + + +AL+ SDIS+ ++L GG + + + + + E Sbjct: 253 SNEILEALQ-EPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNLDRLLMEET 311 Query: 357 GKEPRKDVNPDEAVAIGAAI 376 G +P VA G Sbjct: 312 GIPVVVAEDPLTCVARGGGK 331
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 52.3 bits (125), Expect = 4e-10 Identities = 11/84 (13%), Positives = 31/84 (36%), Gaps = 22/84 (26%) Query: 210 YPEEAKQQQLRGEVRLMVILNAQGGIRAIRLLESSGHSILDEAAKSSVRRGAPFGHFDAN 269 YP A+ ++ G+V++ + G + +++L + ++ + Sbjct: 167 YPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREV---------------- 210 Query: 270 MKDISELRIVRTWRFDPAEAEFEV 293 +R WR++P + + Sbjct: 211 ------KNAMRRWRYEPGKPGSGI 228
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 29.7 bits (67), Expect = 0.049 Identities = 38/147 (25%), Positives = 54/147 (36%), Gaps = 53/147 (36%) Query: 346 QGATESATGILDTLITNGTT--ATGIINNIIGGATSGDSPLGVVTDIIGGVTGGVSGNPL 403 Q G +DT+ITN GI+ IG + I + G +GNP Sbjct: 58 QSQVTREGGAVDTVITNALILDHWGIVKADIG----------LKDGRIAAI--GKAGNP- 104 Query: 404 EIVTDIIGGVTGGVDGNPLEVITDIIGGVTGGVDGNPLEVITDIIGG----VT-GGVDG- 457 D+ GV II G T++I G VT GG+D Sbjct: 105 ----DMQPGV-------------TIIVGPG-----------TEVIAGEGKIVTAGGMDSH 136 Query: 458 ----NPLEVITDIIGGVTGGIGGGTSP 480 P ++ ++ G+T +GGGT P Sbjct: 137 IHFICPQQIEEALMSGLTCMLGGGTGP 163
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 123 bits (311), Expect = 5e-34 Identities = 72/331 (21%), Positives = 119/331 (35%), Gaps = 69/331 (20%) Query: 126 VTLLNDPNVKAVYPNRINRTTTNESLPLINQPQANTNGFTGEGSSVAVIDTGVNYLHSDF 185 V ++ +K + +I P G G VAV+DTG + H D Sbjct: 5 VHIIPYQVIKQEQ----QVNEIPRGVEMIQAPAVWNQT-RGRGVKVAVLDTGCDADHPDL 59 Query: 186 GCTAVNTPSSTCRVVYSFDSAPDDGTLDDDGHGSNVSGIVSK---------VASKTKIIG 236 + R D + D +GHG++V+G ++ VA + ++ Sbjct: 60 KARII-----GGRNFTDDDEGDPEIFKDYNGHGTHVAGTIAATENENGVVGVAPEADLLI 114 Query: 237 IDVFRKVRSQGKWVSTAYDSDILAGINWAVNNAQTYNIKAVNLSLGVPGVKYTSECSDSS 296 I V K + I+ GI +A+ + +++SLG P Sbjct: 115 IKVLNKQ-------GSGQYDWIIQGIYYAIEQ----KVDIISMSLGGPE-------DVPE 156 Query: 297 YGTAFANARAAGVVPVVASGNDAFSDG----ISSPACVAGAVRVGAVYDSNIGGVSWGNP 352 A A A+ ++ + A+GN+ D + P C + VGA Sbjct: 157 LHEAVKKAVASQILVMCAAGNEGDGDDRTDELGYPGCYNEVISVGA-------------- 202 Query: 353 VKCSDPTTAADKVACFSNGGSLVTLLAPGAMITAGGY-----TMGGTSQATPHVAGAIAL 407 + FSN + V L+APG I + T GTS ATPHVAGA+AL Sbjct: 203 ------INFDRHASEFSNSNNEVDLVAPGEDILSTVPGGKYATFSGTSMATPHVAGALAL 256 Query: 408 LRA---NRVNPTESIDQTISRLKTTGKPITD 435 ++ + + ++L P+ + Sbjct: 257 IKQLANASFERDLTEPELYAQLIKRTIPLGN 287
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.8 bits (67), Expect = 0.015 Identities = 14/77 (18%), Positives = 26/77 (33%), Gaps = 1/77 (1%) Query: 193 PITEIHKPLSSA-DHTLQQLLVQQAQALLEQLPNSTQLDQRLQHSILTGLQKNQYQIEHI 251 +S A + ++Q AL L + IL L + Sbjct: 396 AARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKA 455 Query: 252 AAQLGLSVRQLQRHLQQ 268 A LGL+ L++ +++ Sbjct: 456 ADLLGLNRNTLRKKIRE 472
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 29.2 bits (65), Expect = 0.005 Identities = 17/87 (19%), Positives = 22/87 (25%), Gaps = 1/87 (1%) Query: 61 QQVSAAPTNAAPTGAPIPADVPPAPPAGGEMAPPAAPTDAVPPAPNQAPPAPQDPNTPPP 120 Q +S A P PP P E P P + AP P P Sbjct: 48 QPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIP-EPPKEAPVVIEKPKPKPKPKPK 106 Query: 121 PADPSQSADPMAKDGALPADAPMQQAQ 147 P + K +P + Sbjct: 107 PVKKVEQPKRDVKPVESRPASPFENTA 133
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 56.6 bits (136), Expect = 3e-12 Identities = 32/171 (18%), Positives = 56/171 (32%), Gaps = 10/171 (5%) Query: 5 EASFRATRALYTAAELFKQHGFNKVGVDRIVSEAKMTKATFYNYFHSKERLIEMCLLVQK 64 EA L A LF Q G + + I A +T+ Y +F K L + + Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSE 67 Query: 65 EQLKEKVRAISEARQYPDLVHQLRQIYL--LHADLKGAYYLLFKAIFEIKKLYPNAYQTA 122 + E D + LR+I + L + + L I K + Sbjct: 68 SNIGELELEYQAKF-PGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVV 126 Query: 123 LRYRRWLKNEIF----WVLRESKKR---ATYEESNIFVFMIDGAIFGLLGS 166 + +R L E + L+ + + ++ G I GL+ + Sbjct: 127 QQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMEN 177
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 50.6 bits (121), Expect = 6e-09 Identities = 71/366 (19%), Positives = 128/366 (34%), Gaps = 56/366 (15%) Query: 55 LPAFSQSFRISPASSSLALSLTTAFLAISIVLSSAFSQALGRRGVIFTSMLCAAILNIVS 114 LP + F PAS++ + +I + S LG + ++ ++ +++ Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 115 MFTPNWHSLL-MARALEGLLLGGVPAVTMAWIAEEIAPEHLGKTMGLYIAGTAFGGMMGR 173 ++ SLL MAR ++G PA+ M +A I E+ GK GL + A G +G Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 174 VGMGILVEYFSW---------------------------RTALGLLGAICFICSIAFLKL 206 G++ Y W + + G I I F L Sbjct: 157 AIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFML 216 Query: 207 LPASRNFV---------------QKKGLNLDFHMQMWCAHLSNTKLLRLFAIGFLLTSV- 250 S + +K + + N + G ++ Sbjct: 217 FTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLG----KNIPFMIGVLCGGIIFGTV 272 Query: 251 --FVTLFNYATFRLSGAPYSLSQTQISLIFLSYSFGMVSSSLAGSLADRFGKKTMMMSGF 308 FV++ Y + S ++ +IF ++ + G L DR G ++ G Sbjct: 273 AGFVSMVPYMMKDVHQ--LSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGV 330 Query: 309 ALMIVGSL---MTLLTSLFGIIIGIAFITTGFFITHSLTSSSVGAESKQAKAHAS-SLYL 364 + V L L T+ + + I I F+ G T ++ S+ V + KQ +A A SL Sbjct: 331 TFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLN 390 Query: 365 LFYYMG 370 ++ Sbjct: 391 FTSFLS 396
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 40.8 bits (95), Expect = 1e-06 Identities = 28/161 (17%), Positives = 54/161 (33%), Gaps = 24/161 (14%) Query: 7 RLDKDNAAVLLVDHQAGLLSLVRDIDP--DKFKNNVLAVANAAKYFNLPTILTTSFET-- 62 D + A +L+ D Q + + N+ + N +P + T + Sbjct: 25 VPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCVQLGIPVVYTAQPGSQN 84 Query: 63 -----------GPNGPLVPELKEIHPDAPFIPRPGQI-------NAWDNEDFVKAVKATG 104 GP P ++I P + +A+ + ++ ++ G Sbjct: 85 PDDRALLTDFWGPGLNSGPYEEKI--ITELAPEDDDLVLTKWRYSAFKRTNLLEMMRKEG 142 Query: 105 KKQLIIAGVVTEVCVAFPALSALAEGFEVFVITDASGTFNE 145 + QLII G+ + A A E + F + DA F+ Sbjct: 143 RDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVADFSL 183
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 171 bits (436), Expect = 4e-53 Identities = 85/348 (24%), Positives = 142/348 (40%), Gaps = 35/348 (10%) Query: 3 KILVTGGAGYIGSHTCVELLNAGHEVIVFDNLSNSSEESL--TRVQDITQKSLVFVKGDI 60 K LVTG AG+IG H LL AGH+V+ DNL++ + SL R++ + Q F K D+ Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 61 RNANELDRVFQDHSIDAVIHFAGLKAVGESQEKPLIYFDNNIAGSIQLVKSMEKAGIYTL 120 + + +F + V AV S E P Y D+N+ G + +++ I L Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 121 VFSSSATVYDEANISPLNEDMPTGMPSNNYGYTKLIVEQLLQKLSDSNSKWSIALLRYFN 180 +++SS++VY P + D P + Y TK E + S LR+F Sbjct: 122 LYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYS-HLYGLPATGLRFFT 180 Query: 181 PVGAHKSGRIGEDPQGIPNNLMPYVTQVAVGRREKLSIYGNDYNTVDGTGVRDYIHVVDL 240 G P G P+ + T+ A+ + + +Y G RD+ ++ D+ Sbjct: 181 VYG----------PWGRPDMALFKFTK-AMLEGKSIDVYN------YGKMKRDFTYIDDI 223 Query: 241 ANAHLCALNNRLEVTGC---------------RAWNIGTGNGSSVLQVKNTFEQVNGVPV 285 A A + + R +NIG + ++ E G+ Sbjct: 224 AEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEA 283 Query: 286 AFEFAPRRAGDVATSFADNARAVAELGWQPQYGLEDMLKDSWNWQKQN 333 P + GDV + AD +G+ P+ ++D +K+ NW + Sbjct: 284 KKNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDF 331
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 33.6 bits (76), Expect = 0.001 Identities = 18/46 (39%), Positives = 26/46 (56%), Gaps = 4/46 (8%) Query: 232 LALYPLSAFRAMNK----AAETVYETLRKEGTQKNVIDIMQTRKEL 273 L LY F MNK E + E+L+KEG +K+ ID+++ K L Sbjct: 257 LELYAPDMFEYMNKLEKGGFEKISESLKKEGVEKDRIDVLKGEKAL 302
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 28.9 bits (64), Expect = 0.022 Identities = 17/48 (35%), Positives = 25/48 (52%), Gaps = 4/48 (8%) Query: 122 KDAKRAFDYFTKAAAKDHAKAQYNLGVLYDRGEGTAQDYGKAFEWFSR 169 KD ++FD F KD +KA+ L L +G+ +D G EW S+ Sbjct: 695 KDFDKSFDEFKNGKNKDFSKAEETLKAL----KGSVKDLGINPEWISK 738
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 30.3 bits (68), Expect = 0.013 Identities = 18/99 (18%), Positives = 32/99 (32%), Gaps = 13/99 (13%) Query: 378 PKELQQQLERLLPKDKLKAAQLDSQNPEQRHFAELNV--VRRNIKAVPEYNPLEHRPAAY 435 K +Q + P + A+ ++ P + + + L Y Sbjct: 104 KKVQEQPKRDVKPVESRPASPFENTAPARLTSSTATAATSKPVTSVASGPRALSRNQPQY 163 Query: 436 PQRAKVVGLEGESIHVDQWGRIKVRFLFTRTDDHSHDGV 474 P RA+ + +EG+ V+ F T D D V Sbjct: 164 PARAQALRIEGQ-----------VKVKFDVTPDGRVDNV 191
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 30.5 bits (68), Expect = 0.011 Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 4/83 (4%) Query: 140 LSNAKALSEVAKNQQTDPLENLENLKSFIEKLEQQDNAKAKTFKEAIMLLASPNSVALSS 199 LSN K LSE+ K Q+ + L+ +E L E +++Q A A E + + +V + Sbjct: 193 LSNNKNLSELIKQQRENELDQMERL----EDMQEQAQANALKQIEELNKKQAEEAVRQRA 248 Query: 200 NEDIHLSADGQLNQTAGDSINLS 222 + I + D +SI LS Sbjct: 249 KDKISIKTDKSQKSPEDNSIELS 271
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 27.0 bits (59), Expect = 0.021 Identities = 18/65 (27%), Positives = 33/65 (50%), Gaps = 4/65 (6%) Query: 48 KVSEQHFELTSNIPENQGVKITPVDDIDGYNHIKIEG-IPKYKGKYKIV---INTYFYGR 103 K+ + FE S + +GV+ +D + G +K G +P++ +K + +NTY R Sbjct: 270 KLEKGGFEKISESLKKEGVEKDRIDVLKGEKALKASGLVPEHADAFKKIARELNTYILFR 329 Query: 104 GDDKL 108 +KL Sbjct: 330 PVNKL 334
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 378 bits (973), Expect = e-133 Identities = 182/364 (50%), Positives = 242/364 (66%), Gaps = 10/364 (2%) Query: 1 MPRPITAVIHRQALQNNLAVVRKAMPNSKVFAVVKANAYGHGIERVYEAFKAADGFALLD 60 M RPI A + QAL+ NL++VR+A +++V++VVKANAYGHGIER++ A A DGFALL+ Sbjct: 1 MTRPIQASLDLQALKQNLSIVRQAATHARVWSVVKANAYGHGIERIWSAIGATDGFALLN 60 Query: 61 LDEAKRIRALGWTGPILLLEGIFSPQDLFDCVQYQLSFNIHSEAQIEWVEKHAYPAQFDV 120 L+EA +R GW GPIL+LEG F QDL Q++L+ +HS Q++ ++ A D+ Sbjct: 61 LEEAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQNARLKAPLDI 120 Query: 121 CLKMNSGMNRLGFKPQHYVQAWERLNNLANVSKITHMMHFSDADGERFGQQGIDYQINAF 180 LK+NSGMNRLGF+P + W++L +ANV ++T M HF++A+ GI + Sbjct: 121 YLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHFAEAEHP----DGISGAMARI 176 Query: 181 EEIVKDLPGERSVSNSAAILRYQDQLKSDYARSGIMLYGSSPDYPTHSIADWGLQPTMSL 240 E+ + L RS+SNSAA L + + D+ R GI+LYG+SP IA+ GL+P M+L Sbjct: 177 EQAAEGLECRRSLSNSAATLWHPE-AHFDWVRPGIILYGASPSGQWRDIANTGLRPVMTL 235 Query: 241 RSEIISVQHLEPNESVGYGSNFVAEQLMTIGIVACGYADGYQRISPTGTPVLVDSVRTRT 300 SEII VQ L+ E VGYG + A IGIVA GYADGY R +PTGTPVLVD VRT T Sbjct: 236 SSEIIGVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAPTGTPVLVDGVRTMT 295 Query: 301 IGRVSMDMLAVDLTGIDSAKVGSEVVLWGQSSKGVVLPIDDVAVSSGTVGYELMCAVTAR 360 +G VSMDMLAVDLT A +G+ V LWG+ + IDDVA ++GTVGYELMCA+ R Sbjct: 296 VGTVSMDMLAVDLTPCPQAGIGTPVELWGKE-----IKIDDVAAAAGTVGYELMCALALR 350 Query: 361 VQFI 364 V + Sbjct: 351 VPVV 354
>AUTOINDCRSYN#Autoinducer synthesis protein signature. Length = 216 Score = 124 bits (314), Expect = 3e-38 Identities = 36/157 (22%), Positives = 63/157 (40%), Gaps = 9/157 (5%) Query: 13 QNNFSEGLYTKFKNYRYRVFVEYLGWELNCPNNEELDQFDKVDTAYVVAQDRESNIIGCA 72 S L+T R F + L W + C + E DQ+D +T Y+ ++ +I Sbjct: 13 SETKSGELFT----LRKETFKDRLNWAVQCTDGMEFDQYDNNNTTYLFGIK-DNTVICSL 67 Query: 73 RLLPTTQPYLLGEIFPQLLNGMPIPCSPEIWELSRFSAVDFSNPPSSASQAVSSPVSIAI 132 R + T P ++ F + IP E SRF VD S P+S + Sbjct: 68 RFIETKYPNMITGTFFPYFKEINIPEGN-YLESSRF-FVDKSRAKDILGNE--YPISSML 123 Query: 133 LQKSINFAREQGAKQLITTSPLGVERLLRAAGFRAHR 169 IN+++++G + T + +L+ +G+ Sbjct: 124 FLSMINYSKDKGYDGIYTIVSHPMLTILKRSGWGIRV 160
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 26.1 bits (57), Expect = 0.016 Identities = 21/82 (25%), Positives = 38/82 (46%), Gaps = 5/82 (6%) Query: 3 KDKVYWSAIIRTLVAKEMRVEPETIDPEQKFTSYGLDSIVALSVSGDLEDLTKL--ELEP 60 K V+ IR +A+ ++ PE I ++ GLDS+ +++ +E + E+ Sbjct: 226 KKNVFTCENIRKQIAELLQETPEDITDQEDLLDRGLDSVRIMTL---VEQWRREGAEVTF 282 Query: 61 TLLWDYPTINALAEYLVSELQQ 82 L + PTI + L + QQ Sbjct: 283 VELAERPTIEEWQKLLTTRSQQ 304
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 86.0 bits (213), Expect = 5e-19 Identities = 49/233 (21%), Positives = 98/233 (42%), Gaps = 15/233 (6%) Query: 757 QRYAKITILMKTGSN-----HRIKEILESLKTYMAAQLGDKAVVSFGGDVTQTIALTETM 811 + A + I + TG+N IK L L+ + G K + + D T + + Sbjct: 284 KPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQ--GMKVLYPY--DTTPFV---QLS 336 Query: 812 VHGKLMNILQISFAVFFISALVFRSISAGLIVLTPLLFSILAIFGVMGWLDIPLNIPNSL 871 +H + + + VF + L +++ A LI + +L F ++ +N Sbjct: 337 IHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMF 396 Query: 872 ISAMAVGIGADYAIYFLYRLREILREEGGDIKDAIRKTLSTAGKASLFVATAVAGGYGVL 931 +A+G+ D AI + + ++ E+ K+A K++S A + +A ++ + + Sbjct: 397 GMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPM 456 Query: 932 SLSQG--FHVHQWLAMFIVIAMLFSVFATLIMVPTM-ILILKPRFIFSSNKKS 981 + G +++ ++ IV AM SV LI+ P + +LKP K Sbjct: 457 AFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKG 509 Score = 60.6 bits (147), Expect = 3e-11 Identities = 27/156 (17%), Positives = 63/156 (40%), Gaps = 10/156 (6%) Query: 824 FAVFFISALVFRSISAGLIVLTPLLFSILAIFGVMGWLDIPLNIPNSLISAMAVGIGADY 883 VF A ++ S S + V+ + I+ + + ++ + +G+ A Sbjct: 881 VVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKN 940 Query: 884 AIYFLYRLREILREEGGDIKDAIRKTLSTAGKASL--FVATAVAGGYGVL----SLSQGF 937 AI + ++++ +EG + +A A + L + T++A GVL S G Sbjct: 941 AILIVEFAKDLMEKEGKGVVEATLM----AVRMRLRPILMTSLAFILGVLPLAISNGAGS 996 Query: 938 HVHQWLAMFIVIAMLFSVFATLIMVPTMILILKPRF 973 + + ++ M+ + + VP ++++ F Sbjct: 997 GAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRRCF 1032 Score = 39.8 bits (93), Expect = 7e-05 Identities = 42/223 (18%), Positives = 85/223 (38%), Gaps = 30/223 (13%) Query: 426 VLVIGLLHFEAFRSKQGLILPLVTALLAVAWGMGMMGLFKQPMDIFNSPTPILILAIAAG 485 V ++ L + R+ + + LL + G + +F ++LAI Sbjct: 351 VFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFG-----MVLAIGLL 405 Query: 486 --HAVQLLKRYYEDFDRLIAQGMEPKAANSEAVVQSLVRVGPVMVLAGGIAAAGFFSLLT 543 A+ +++ ++ + PK EA +S+ ++ +V + +A F + Sbjct: 406 VDDAIVVVENVE---RVMMEDKLPPK----EATEKSMSQIQGALVGIAMVLSAVFIPMAF 458 Query: 544 FNIPT---IRSFGIFTGIGIISTLIIEMTFIPALRSML--PPPSVTKVKRKGLPIW---- 594 F T R F I + ++++ + PAL + L P + + G W Sbjct: 459 FGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTT 518 Query: 595 -DWIPNRIGDA---ILSVRPRMILMTAIATIG---VFLAIGTS 630 D N ++ IL R +L+ A+ G +FL + +S Sbjct: 519 FDHSVNHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSS 561 Score = 35.2 bits (81), Expect = 0.002 Identities = 27/163 (16%), Positives = 63/163 (38%), Gaps = 20/163 (12%) Query: 420 ILFPIAVLVIGLLHFEAFRSKQGLILPLVTALLAVAWGMGMMGLFKQPMDIFNSPTPILI 479 L I+ +V+ L + S + ++ L + + LF Q D++ + Sbjct: 874 ALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTT 933 Query: 480 LAIAAGHAVQLLKRYYEDF--DRLIAQGMEPKAANSEAVVQSLVRVGPVMVLAGGIAAAG 537 + ++A +A+ ++ +F D + +G A A +R+ P+++ + A Sbjct: 934 IGLSAKNAILIV-----EFAKDLMEKEGKGVVEATLMA---VRMRLRPILM----TSLAF 981 Query: 538 FFSLLTFNIPTIRSFGIFTGI------GIISTLIIEMTFIPAL 574 +L I G + G++S ++ + F+P Sbjct: 982 ILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVF 1024
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 57.5 bits (139), Expect = 5e-11 Identities = 25/86 (29%), Positives = 34/86 (39%), Gaps = 3/86 (3%) Query: 16 TILVTGAAGFIGSRLIVELLREGHQVIAALRNTATKKEKLLGFIATQGLTDPSISFVEYD 75 LVTGAAGFIG + LL GHQV+ + N + L + L P F + D Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVV-GIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 76 LSHDFKLDSLLTDAQTKIHVVYHLAA 101 L+ + L V+ Sbjct: 61 LADREGMTDLFASGH--FERVFISPH 84
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 82.6 bits (204), Expect = 1e-20 Identities = 50/224 (22%), Positives = 78/224 (34%), Gaps = 21/224 (9%) Query: 2 VSTHPIYLIAKEVTQGVEEPQLLLK-GQTGHDVQLTPAHRKAINDASLVIWLGKAHE--- 57 + I I K + + ++ GQ H+ + P K ++A L+ + G E Sbjct: 37 ATNSIIADITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGG 96 Query: 58 -APLNKLLGN-----NKKAIALLDSGIVSVLPQRSTRGAALPNTVDTHVWLEPNNAVRIG 111 A KL+ N NK A+ S V V+ G D H WL N + Sbjct: 97 NAWFTKLVENAKKTENKDYFAV--SDGVDVIY---LEGQNEKGKEDPHAWLNLENGIIFA 151 Query: 112 FFIAALRSQQHPENKAKYWNNANVFARKMFQAAQAYDS-----SSNGKPYWAYHDAYQYL 166 IA S + P NK Y N + K+ + + + K A++Y Sbjct: 152 KNIAKQLSAKDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYF 211 Query: 167 ERSLNLKFAGALTDDPHVAPTAAQIKYLND-SRPKNQMCLLAES 209 ++ + A + T QIK L + R L ES Sbjct: 212 SKAYGVPSAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVES 255
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 27.8 bits (61), Expect = 0.020 Identities = 22/93 (23%), Positives = 36/93 (38%), Gaps = 6/93 (6%) Query: 29 LINAISERQRKIADGLNAAEKAKADLADAQAQVKQELDAAK-----AQAAQLIEQANRRA 83 AIS Q ++ + L AA+ + A +A+ + +A + A+ I AN A Sbjct: 193 FTEAISSLQIRM-NTLTAAKASIEAAAANKAREQAAAEAKRKAEEQARQQAAIRAANTYA 251 Query: 84 AQLIEEARTQAAAEGERIRQQAKEAVDQEINSA 116 AA G Q ++ Q I+ A Sbjct: 252 MPANGSVVATAAGRGLIQVAQGAASLAQAISDA 284
>INVEPROTEIN#Salmonella/Shigella invasion protein E (InvE) signature. Length = 372 Score = 35.1 bits (80), Expect = 2e-04 Identities = 28/91 (30%), Positives = 45/91 (49%), Gaps = 9/91 (9%) Query: 30 LKGRDDQRLQKILQLAEPFGISVQK-ASRDSLEKLAGL-PFHQGVVAAVRPHPTLNEKDL 87 L+ + ++IL+L ISV A D L + L P +V +R L KDL Sbjct: 86 LEDEALPKAKQILKL-----ISVHGGALEDFLRQARSLFPDPSDLVLVLRE--LLRRKDL 138 Query: 88 DQILAETPDALLLALDQVTDPHNLGACIRTA 118 ++I+ + ++LL +++ TDP L A I A Sbjct: 139 EEIVRKKLESLLKHVEEQTDPKTLKAGINCA 169
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 271 bits (695), Expect = 5e-94 Identities = 126/240 (52%), Positives = 160/240 (66%), Gaps = 2/240 (0%) Query: 4 QECQILLNPEQPMIEHEKLTLSKPASSCPACQQPIRWYQNIPVISWLMLRGKCGHCQHPI 63 E + NP+ ++ L P S CP C PI +NIP++SWL LRG+C CQ PI Sbjct: 47 AEYRSYFNPDDEGVDEPPYNLMVPRSCCPHCNHPITALENIPLLSWLWLRGRCRGCQAPI 106 Query: 64 SIRYPAIELLTMLCSLVVVMVFGPTLQMLWGLVLTWILIALTFIDFDTQLLPDRFTLPLA 123 S RYP +ELLT L S+ V M P L L+LTW+L+ALTFID D LLPD+ TLPL Sbjct: 107 SARYPLVELLTALLSVAVAMTLAPGWGTLAALLLTWVLVALTFIDLDKMLLPDQLTLPLL 166 Query: 124 ALGLGINTFSIYTSPNSAIWGYLIGFLCLWIVYYLFKVITGKEGMGYGDFKLLAALGAWM 183 GL N + S A+ G + G+L LW +Y+ FK++TGKEGMGYGDFKLLAALGAW+ Sbjct: 167 WGGLLFNLLGGFVSLGDAVIGAMAGYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWL 226 Query: 184 GPLMLPLIVLLSSLLGAIIGIILLKLRNDN--QPFAFGPYIAIAGWVAFLWGDQIMKIYL 241 G LP+++LLSSL+GA +GI L+ LRN + +P FGPY+AIAGW+A LWGD I + YL Sbjct: 227 GWQALPIVLLLSSLVGAFMGIGLILLRNHHQSKPIPFGPYLAIAGWIALLWGDSITRWYL 286
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 59.0 bits (143), Expect = 1e-14 Identities = 21/49 (42%), Positives = 28/49 (57%) Query: 1 MQEIIAYFIQNLTALYIAVALLSLCIGSFLNVVIYRTPKMMEQDWQQEC 49 M ++ + V L SL IGSFLNVVI+R P M+E++WQ E Sbjct: 1 MALLLELAHGLPWLYFSLVFLFSLMIGSFLNVVIHRLPIMLEREWQAEY 49
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 402 bits (1035), Expect = e-141 Identities = 119/409 (29%), Positives = 220/409 (53%), Gaps = 12/409 (2%) Query: 9 MPTFAYEGVDRKGVKIKGELPAKNMALAKVTLRKQGVTVRNIREKRKNILEG-------L 61 M + Y+ +D +G K +G A + A+ LR++G+ ++ E R + + Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 62 FKKKVSTLDITIFTRQLATMMKAGVPLVQGFEIVAEGLENPAMREVVLGIKGEVEGGSTF 121 K ++ST D+ + TRQLAT++ A +PL + + VA+ E P + +++ ++ +V G + Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 122 ASALRKYPQHFDNLFCSLVESGEQSGALETMLDRVAIYKEKSELLKQKIKKAMKYPATVI 181 A A++ +P F+ L+C++V +GE SG L+ +L+R+A Y E+ + ++ +I++AM YP + Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 182 VVAVVVTIILMVKVVPVFQDLFSSFGADLPAFTQMVVNMSKWMQEY--WFIMIIVIGAVI 239 VVA+ V IL+ VVP + F LP T++++ MS ++ + W ++ ++ G + Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMA 240 Query: 240 AAFLEAKKRSKKFRDGLDKLTLKLPIFGDLVYKAIIARYSRTLATTFAAGVPLIDALEST 299 + R +K R + L LP+ G + ARY+RTL+ A+ VPL+ A+ + Sbjct: 241 FRVM---LRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRIS 297 Query: 300 AGATNNVIYEEAVMKIREDVATGQQLQFAMRVSNRFPSMAIQMVAIGEESGALDSMLDKV 359 +N + + V G L A+ + FP M M+A GE SG LDSML++ Sbjct: 298 GDVMSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERA 357 Query: 360 ATYYENEVDNAVDGLTSMMEPLIMAILGVLVGGLVIAMYLPIFQMGSVI 408 A + E + + + EPL++ + +V +V+A+ PI Q+ +++ Sbjct: 358 ADNQDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>SECGEXPORT#Protein-export SecG membrane protein signature. Length = 110 Score = 96.9 bits (241), Expect = 9e-30 Identities = 44/98 (44%), Positives = 65/98 (66%) Query: 1 MHSFVLIVHIILAVLMIALILVQHGKGADAGASFGGGGAATVFGASGSGNFLTRLTAILT 60 M+ +L+V +I+A+ ++ LI++Q GKGAD GASFG G +AT+FG+SGSGNF+TR+TA+L Sbjct: 1 MYEALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFGSSGSGNFMTRMTALLA 60 Query: 61 ALFFVTSLTLAVFAKKQTTDAYSLKTVQTTAPVQTTSP 98 LFF+ SL L +T + + A + T P Sbjct: 61 TLFFIISLVLGNINSNKTNKGSEWENLSAPAKTEQTQP 98
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 59.3 bits (143), Expect = 6e-11 Identities = 41/300 (13%), Positives = 112/300 (37%), Gaps = 1/300 (0%) Query: 646 RLDEIEQALEKQQPQLQALDEIVVQQKDELAQLQSGVQHKQQVVKQKQKDLQQLDVQIAK 705 + ++ + + L E + K++L + + K +++ + L+ + Sbjct: 72 KNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEG 131 Query: 706 QQTAAQAFLLQKQQLKDQLGQLDMQLEEDAMQKDDLEIDLHALAIKLETILPDYKTLQFR 765 + A + + L+ + L + + + A + K++T+ + L+ R Sbjct: 132 AMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEAR 191 Query: 766 VEELTEQLDEQQQALQHQQQEREILRRNSTQTTQQIELLEKDISFLQSQYQQIAAQMEQA 825 EL + L+ + + L + LEK + + +A+++ Sbjct: 192 QAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTL 251 Query: 826 KKFVDPIQLELPNLESEFQQQFAQTEKLQKNWNEWQLELNSVQEKQQTLTDQRHQYQQKD 885 + ++ LE + + + E +++ ++ L Q Sbjct: 252 EAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANR 311 Query: 886 EQLREQLEAKRLAWQAAKSDREHYQEQLKELNAELQKGLQIDLAEHQQKLEKVQKQFEKI 945 + LR L+A R A + +++ + +EQ K A + L+ DL ++ ++++ + +K+ Sbjct: 312 QSLRRDLDASREAKKQLEAEHQKLEEQNKISEASR-QSLRRDLDASREAKKQLEAEHQKL 370 Score = 57.0 bits (137), Expect = 3e-10 Identities = 50/310 (16%), Positives = 112/310 (36%), Gaps = 13/310 (4%) Query: 647 LDEIEQALEKQQPQLQALDEIVVQQKDELAQLQSGVQHKQQVVKQKQKDLQQLDVQIAKQ 706 L ++ L K L + + + A L+ ++ ++ L+ + A Sbjct: 94 LSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAAL 153 Query: 707 QTAAQAFLLQKQQLKDQLGQLDMQLEEDAMQKDDLEIDLHALAIKLETILPDYKTLQFRV 766 + + +++ +K LE L LE + ++ Sbjct: 154 AARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKI 213 Query: 767 EELTEQLDEQQQALQHQQQEREILRRNSTQTTQQIELLEKDISFLQSQYQQIAAQMEQAK 826 + L + ++ E ST + +I+ LE + + L+++ ++ +E A Sbjct: 214 KTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAM 273 Query: 827 KFVDPIQLELPNLESEFQQQFAQTEKLQKNWNEWQLELNSVQEKQQTLTDQRHQYQQKDE 886 F ++ LE+E A+ L+ S++ + + Q + + + Sbjct: 274 NFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQ 333 Query: 887 QLREQLEAKRLAWQAAKSDREHYQEQLKELNAELQK-------------GLQIDLAEHQQ 933 +L EQ + + Q+ + D + +E K+L AE QK L+ DL ++ Sbjct: 334 KLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASRE 393 Query: 934 KLEKVQKQFE 943 ++V+K E Sbjct: 394 AKKQVEKALE 403 Score = 55.8 bits (134), Expect = 7e-10 Identities = 49/272 (18%), Positives = 102/272 (37%), Gaps = 7/272 (2%) Query: 651 EQALEKQQPQLQALDEIVVQQKDELAQLQSGVQHKQQVVKQKQKDLQQLDVQIAKQQTAA 710 + +AL + + +EL+ + ++ + + +K +Q+L+ + A + A Sbjct: 70 KLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKAL 129 Query: 711 QAFLLQKQQLKDQLGQLDMQLEEDAMQKDDLEIDLHALAIKLETILPDYKTLQFRVEELT 770 + + ++ L+ + A +K DLE L KTL+ L Sbjct: 130 EGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALE 189 Query: 771 EQLDEQQQALQHQQQEREILRRNSTQTTQQIELLEKDISFLQSQYQQIAAQMEQAKKFVD 830 + E ++AL+ LE + + L ++ + +E A F Sbjct: 190 ARQAELEKALEGAMNFSTADSAKIKT-------LEAEKAALAARKADLEKALEGAMNFST 242 Query: 831 PIQLELPNLESEFQQQFAQTEKLQKNWNEWQLELNSVQEKQQTLTDQRHQYQQKDEQLRE 890 ++ LE+E A+ +L+K + K +TL ++ + + L Sbjct: 243 ADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEH 302 Query: 891 QLEAKRLAWQAAKSDREHYQEQLKELNAELQK 922 Q + Q+ + D + +E K+L AE QK Sbjct: 303 QSQVLNANRQSLRRDLDASREAKKQLEAEHQK 334 Score = 45.8 bits (108), Expect = 8e-07 Identities = 33/253 (13%), Positives = 82/253 (32%), Gaps = 1/253 (0%) Query: 742 EIDLHALAIKLETILPDYKTLQFRVEELTEQLDEQQQALQHQQQEREILRRNSTQTTQQI 801 L + + + + TL+ + +L+ + +E + + + + Sbjct: 49 TDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSL 108 Query: 802 ELLEKDISFLQSQYQQIAAQMEQAKKFVDPIQLELPNLESEFQQQFAQTEKLQKNWNEWQ 861 I L+++ + +E A F ++ LE+E A+ L+K Sbjct: 109 SEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAM 168 Query: 862 LELNSVQEKQQTLTDQRHQYQQKDEQLREQLEAKRLAWQAAKSDREHYQEQLKELNAELQ 921 + K +TL ++ + + +L + LE A + + + + L A Sbjct: 169 NFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKA 228 Query: 922 KGLQIDLAEHQQKLEKVQKQFEKIGAVNLAASQEFEEVSQRFDELSHQIQDLENTVTQLK 981 L+ L + + + A A E+ + + + + L+ Sbjct: 229 D-LEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLE 287 Query: 982 DAMKSIDQETRKL 994 +++ E L Sbjct: 288 AEKAALEAEKADL 300 Score = 30.8 bits (69), Expect = 0.033 Identities = 42/277 (15%), Positives = 100/277 (36%), Gaps = 8/277 (2%) Query: 145 EQGMINRLVDAKPEEMRVFIEEAAGVSRYQARRRETLQHLEHTEQNLSRLDDIALELKSQ 204 Q + + ++ + + +A LE + Sbjct: 191 RQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKT 250 Query: 205 LKTLKRQSEAAVQYKTLESQIRTLKIEILSFQAEKSVRLQEEYTVQMNELGETFKLVRSE 264 L+ K EA + S + + + + +L +++ + Sbjct: 251 LEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNAN 310 Query: 265 LSTIEHDLEATSALFQRLIQQSSPLQQEWQQAEKKLSELKMTLEQKQSLYQQNSTTLVQL 324 ++ DL+A+ ++L + L+++ + +E L+ L+ + + QL Sbjct: 311 RQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKK-------QL 363 Query: 325 EQQRFQTKERLQLSELQLETLNNQLEEQTEALAGVEHTATEAEQNFADLQSQQKQAQQQF 384 E + + +E+ ++SE ++L L+ EA VE EA A L+ K+ ++ Sbjct: 364 EAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESK 423 Query: 385 EQV-KAQVEKQQQQKMQMSAQIEQLGKNVQRIEQQKE 420 + K + E Q + + + A E+L K + + + + Sbjct: 424 KLTEKEKAELQAKLEAEAKALKEKLAKQAEELAKLRA 460
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 33.9 bits (77), Expect = 0.001 Identities = 31/127 (24%), Positives = 58/127 (45%), Gaps = 12/127 (9%) Query: 54 RDQLEKNEAESVAVTSAERVEPTLSEAAPSQVPETKQSEIETVEPAKAIQTEQTQ---AV 110 R+ ++ ++ A T V + SE +Q ETK++ E ++TE+TQ V Sbjct: 1066 REVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKV 1125 Query: 111 VENASVEEIKSEETVPSSTIHKDGSVELVDTVSVKPEAEALAKENLEAESEKTEPELSLN 170 S ++ +SE P + + + E TV++K E ++ N A++E +P + Sbjct: 1126 TSQVSPKQEQSETVQPQA----EPARENDPTVNIK---EPQSQTNTTADTE--QPAKETS 1176 Query: 171 PNIETAE 177 N+E Sbjct: 1177 SNVEQPV 1183 Score = 32.3 bits (73), Expect = 0.004 Identities = 25/125 (20%), Positives = 47/125 (37%), Gaps = 19/125 (15%) Query: 79 EAAPSQVPETKQSEIETVE----------------PAKAIQTEQTQAVVENASVEE--IK 120 + P Q+++ +V PA A +E T+ V EN+ E ++ Sbjct: 993 DTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVE 1052 Query: 121 SEETVPSSTIHKDGSVELVDTVSVKPEAEALAKENLEAESEKTEP-ELSLNPNIETAEIA 179 E + T ++ V +VK + +E+++T+ E +E E A Sbjct: 1053 KNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKA 1112 Query: 180 EFEGE 184 + E E Sbjct: 1113 KVETE 1117
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 36.0 bits (83), Expect = 2e-05 Identities = 19/97 (19%), Positives = 35/97 (36%), Gaps = 14/97 (14%) Query: 46 HEMQEE-----ASHADAIIRRVLFLGAKPNMHREDINVGTDV---------VSCLKADLA 91 HE EE A D I R+L +G +P ++ + ++A + Sbjct: 47 HEKFEELYDHAAETVDTIAERLLAIGGQPVATVKEYTEHASITDGGNETSASEMVQALVN 106 Query: 92 LEYHVREKLATGIKLCEEKGDYISRDMLRQQLSDTEE 128 + + I L EE D + D+ + + E+ Sbjct: 107 DYKQISSESKFVIGLAEENQDNATADLFVGLIEEVEK 143
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 40.2 bits (94), Expect = 1e-05 Identities = 65/369 (17%), Positives = 127/369 (34%), Gaps = 23/369 (6%) Query: 38 PLIPFAQQRLNLNH---ADFGLLLLCMGIGSMIAMPATGALVKRWGCRPLIALALMLLMV 94 P++P + L ++ A +G+LL + P GAL R+G RP++ ++L V Sbjct: 26 PVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAV 85 Query: 95 LLPSLTMWSSIVTMAVALFIFGSAAGCLGVAINLQAVVVEKHSVRALMSSFHGMCSLGGL 154 + + + + + G VA A + + RA F C G+ Sbjct: 86 DYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDE-RARHFGFMSACFGFGM 144 Query: 155 TGAMLVTALLAVGLSPLMSTLSVVMILLVIGGVAIPSCLTSFEQDEKPHEDTIQAPKKLY 214 ++ L+ G SP + + + S + + +P P + Sbjct: 145 VAGPVLGGLMG-GFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASF 203 Query: 215 RPDGIILLIGMMCFIAFL----SEGAAMDWGGIYLTSKYQLNPAFAGLAYTFFAL--SMT 268 R + ++ + + F+ + A W I+ ++ + G++ F + S+ Sbjct: 204 RWARGMTVVAALMAVFFIMQLVGQVPAALW-VIFGEDRFHWDATTIGISLAAFGILHSLA 262 Query: 269 TGRFAGHILLKQWGEKNIVTYSAIGAAIGMAVIVTAPVWQVVVLGYALLGLG--CSNIVP 326 G + + GE+ + I G ++ A + LL G + Sbjct: 263 QAMITG-PVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGMPALQ 321 Query: 327 VMFSRVGRQNNMPKAAALSLVSTIAYTGSLSGPALIGLI-----GEWTGLSTVLTGVAVL 381 M SR + + + + S+ GP L I W G + G A+ Sbjct: 322 AMLSRQVDEERQGQLQGSL--AALTSLTSIVGPLLFTAIYAASITTWNGW-AWIAGAALY 378 Query: 382 LFIIALLNR 390 L + L R Sbjct: 379 LLCLPALRR 387
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 71.1 bits (174), Expect = 2e-15 Identities = 70/405 (17%), Positives = 147/405 (36%), Gaps = 17/405 (4%) Query: 21 HWKVLIWCLLIIIFDGYDLVIYGVALPLLMQQWSLTAVEAGLLASAALFGMMFGAMIFGT 80 H ++LIW ++ F + ++ V+LP + ++ + +A + G ++G Sbjct: 12 HNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGK 71 Query: 81 LSDKLGRKKTILICVTLFSGFTFIGAFAKGPTEFAIL-RFIAGLGIGGVMPNVVALMTEY 139 LSD+LG K+ +L + + + IG I+ RFI G G V+ ++ Y Sbjct: 72 LSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARY 131 Query: 140 APKKIRSTLVAIMFSGYAIGGMTSALLGAWLVKDMGWQIMFLIAGTPLLLLPLIWKFLPE 199 PK+ R ++ S A+G +G + + W + LI ++ +P + K L + Sbjct: 132 IPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKK 191 Query: 200 SLAFLVKSNHSEQAKSIVSKIAPQTQVNANTQLVLNENT-------TTDAPVRALFQQGR 252 + + V + + + L + V F Sbjct: 192 EVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPG 251 Query: 253 TFSTFMFWIAFFMCLLMVYALGSW--LPKLMLQAGYSLG---ASMLFLFALNIGGMVGAI 307 F I ++ + + + M++ + L + +F + ++ Sbjct: 252 LGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGY 311 Query: 308 GGGALADRFHLKPVITIMFIVGSAALILLGI---NSPQFILYSLIAIAGAATIGSQILLY 364 GG L DR V+ I S + + + F+ ++ + G + ++ ++ Sbjct: 312 IGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSF-TKTVIS 370 Query: 365 TFVAQFYPTALRSTGMGWASGIGRIGAIIGPVLTGALLTLELPHQ 409 T V+ GM + + G + G LL++ L Q Sbjct: 371 TIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLDQ 415 Score = 32.5 bits (74), Expect = 0.004 Identities = 27/121 (22%), Positives = 49/121 (40%), Gaps = 6/121 (4%) Query: 304 VGAIGGGALADRFHLKPVITIMFIVGSAALILLGINSPQF---ILYSLIAIAGAATIGSQ 360 +G G L+D+ +K ++ I+ ++ + F I+ I AGAA + Sbjct: 64 IGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPA- 122 Query: 361 ILLYTFVAQFYPTALRSTGMGWASGIGRIGAIIGPVLTGALL-TLELPHQMNFLAIAIPG 419 L+ VA++ P R G I +G +GP + G + + + + I I Sbjct: 123 -LVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIIT 181 Query: 420 V 420 V Sbjct: 182 V 182
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.8 bits (67), Expect = 0.044 Identities = 12/45 (26%), Positives = 22/45 (48%) Query: 590 LKAPMPGVVTQVLVSANHSVKKDDILMTLEAMKMEYTIRAPKDGL 634 +K +V +++V SV+K D+L+ L A+ E + L Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSL 143
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 28.6 bits (64), Expect = 0.019 Identities = 27/149 (18%), Positives = 57/149 (38%), Gaps = 29/149 (19%) Query: 54 RVHGIAFGGGMGLASACDICIASTDAKFATSEVRLGLAPSTISPY---VIRAIGARQASR 110 ++ GIA G+ +A A F E + + ++I+ + + A + S+ Sbjct: 4 KITGIAASSGVAIAKA-----------FIHLEPNVDIEKTSITDVSTEIEKLTAALEKSK 52 Query: 111 YFLTAERISARDAKHIGLAH--------EVADAEDLDKKVQEIIDALLLGGPHAQAASKQ 162 L I + +G V D +L ++ I+ +A+ A K+ Sbjct: 53 EEL--RAIKDQTEASMGADKAEIFAAHLLVLDDPELVDGIKGKIEN---EQMNAEYALKE 107 Query: 163 LIQMVSNQ--TMSNDLLQQTAHHIAQVRQ 189 + M + +M N+ +++ A I V + Sbjct: 108 VSDMFVSMFESMDNEYMKERAADIRDVSK 136
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 70.0 bits (171), Expect = 4e-17 Identities = 30/168 (17%), Positives = 66/168 (39%), Gaps = 11/168 (6%) Query: 1 MQERMEQNRKSILNSARKIISEGGFKDAQIQTIAEQAGVSSGLVYRYFDNKSQVLIEVLS 60 ++ ++ R+ IL+ A ++ S+ G + IA+ AGV+ G +Y +F +KS + E+ Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 61 EAINTELLVIDSITESELSAKQKLHKAVATFVKRALNSPQLAYSLMFEPVDSTVEH--ER 118 + + + + + + V + + + L+ E + E E Sbjct: 65 LSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEE-RRRLLMEIIFHKCEFVGEM 123 Query: 119 FRVKQLIKQS-------IKKILADGNASGEFVLD-DLNTAALCVVGAM 158 V+Q + I++ L + D AA+ + G + Sbjct: 124 AVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYI 171
>PF03944#delta endotoxin Length = 633 Score = 36.6 bits (84), Expect = 2e-04 Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 3/63 (4%) Query: 196 LAKQHQFDETINIQFTSGTTGNPKGTMLTHHNILNNGYFVGEG---IRLTPQDKVCISVP 252 L + ++E NI SGT G + M++ HN NN + V E I L P D ++ Sbjct: 438 LRRPLHYNEIRNIASPSGTPGGARAYMVSVHNRKNNIHAVHENGSMIHLAPNDYTGFTIS 497 Query: 253 LFH 255 H Sbjct: 498 PIH 500
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 53.3 bits (128), Expect = 1e-09 Identities = 38/180 (21%), Positives = 77/180 (42%), Gaps = 1/180 (0%) Query: 21 HWSILLWCLLIIIFDGYDLVIYGVVLPLLMQEWSLTAVQAGMLASTALCGMMFGAMFFGT 80 H IL+W ++ F + ++ V LP + +++ + + + G +G Sbjct: 12 HNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGK 71 Query: 81 LADKIGRKKVILICVTFFSGFTFLGAFASSPLEFGVL-RFLAGLGIGGVMPNLVALTSEY 139 L+D++G K+++L + + +G S ++ RF+ G G ++ + + Y Sbjct: 72 LSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARY 131 Query: 140 APKRIRSTLVGSMFSGYAIGGILSALIGSYLVESQGWQIMFLIAGIPLFLLPVIWKFLPE 199 PK R G + S A+G + IG + W + LI I + +P + K L + Sbjct: 132 IPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKK 191
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1062 bits (2747), Expect = 0.0 Identities = 511/1028 (49%), Positives = 703/1028 (68%), Gaps = 9/1028 (0%) Query: 2 MSQFFIRRPVFAWVIAIFIILFGVLSIPKLPIARFPSVAPPEVNITASYPGATPKTINDS 61 M+ FFIRRP+FAWV+AI +++ G L+I +LP+A++P++APP V+++A+YPGA +T+ D+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 62 VITLIEREMSGVKNLLYYSATTDSSGTAEITATFKPGTDVDMAQVDVQNKIKAVEARLPQ 121 V +IE+ M+G+ NL+Y S+T+DS+G+ IT TF+ GTD D+AQV VQNK++ LPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 122 VVRQQGLAVEASSSGFLMLVGLNSPNHRYSEVDLSDYLVRNVVEELKRVEGVGKIQSFGA 181 V+QQG++VE SSS +LM+ G S N ++ D+SDY+ NV + L R+ GVG +Q FGA Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 182 EKAMRIWVDPNKLVSYGLSISDVNNAIRNNNIDIAPGRLGDRPLVNGQLITIPLSAQGQL 241 + AMRIW+D + L Y L+ DV N ++ N IA G+LG P + GQ + + AQ + Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 242 ENVEQFKNISLKSNISGANIKLSDVADVEMGAQSYNFAILENGKPATAAAIQLSPGANAV 301 +N E+F ++L+ N G+ ++L DVA VE+G ++YN NGKPA I+L+ GANA+ Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 302 KTADAVKQKLEELKVNLPEGMQFSVPYDTAPFVKISIEKVVHTLIEAMVLVFIVMYLFLH 361 TA A+K KL EL+ P+GM+ PYDT PFV++SI +VV TL EA++LVF+VMYLFL Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 362 NVRYTLIPAIVAPIALLGTFTIMLLTGYSINVLTMFGMVLAIGIIVDDAIVVVENVERIM 421 N+R TLIP I P+ LLGTF I+ GYSIN LTMFGMVLAIG++VDDAIVVVENVER+M Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 422 ATEGLSPKEATSKAMTEITSPIIGITLVLAAVFLPMALASGSVGIIYRQFTITMSVSILF 481 + L PKEAT K+M++I ++GI +VL+AVF+PMA GS G IYRQF+IT+ ++ Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 482 SAFLALTLTPALCATLLKPVDANHQ--KKGFYAWFDRSFDKVTKKYEAILLKVVKHTIPT 539 S +AL LTPALCATLLKPV A H K GF+ WF+ +FD Y + K++ T Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 Query: 540 LIIFVVITGLTFAGMKYWPTAFMPEEDQGWFLTSFQLPSDATAERTTKIVKDFEGHL--N 597 L+I+ +I P++F+PEEDQG FLT QLP+ AT ERT K++ + N Sbjct: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 Query: 598 EQSDVKSNISIMGWGFSGAGQNVALAFTTLKDFGERDKSTTDYTNLI---NAEMANSKEG 654 E+++V+S ++ G+ FSG QN +AF +LK + ER+ +I E+ ++G Sbjct: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG 660 Query: 655 TTMSVLPPAIDELGTSSGFSLRLQDKANLGMPALISAQEKLMEMAAQN-KKFYMVYPEGL 713 + PAI ELGT++GF L D+A LG AL A+ +L+ MAAQ+ V P GL Sbjct: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 Query: 714 PQGDNISLKIDREKLNTLGVSFASVSDIISTSMGSMYINDFPNQGRMQQVIVQANAKSRM 773 L++D+EK LGVS + ++ IST++G Y+NDF ++GR++++ VQA+AK RM Sbjct: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM 780 Query: 774 HLKDILSLKVAGANGQLVSLSEVVIPQWNKLPQQYNRYNGRPSLSIAGVPNIGVSSGDAM 833 +D+ L V ANG++V S W + RYNG PS+ I G G SSGDAM Sbjct: 781 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM 840 Query: 834 REMEKLIAKLPQGIGYEWTGISLQEKQSESQMVFLIALSMLVVFLVLAALYESWSIPLSV 893 ME L +KLP GIGY+WTG+S QE+ S +Q L+A+S +VVFL LAALYESWSIP+SV Sbjct: 841 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900 Query: 894 MLVVPLGIFGAVLAIMLRGMPNDIFFKIGLITIIGLSAKNAILIVEFAK-MLKEEGMTLI 952 MLVVPLGI G +LA L ND++F +GL+T IGLSAKNAILIVEFAK ++++EG ++ Sbjct: 901 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV 960 Query: 953 EAAVAAAKLRLRPILMTSLAFTCGVIPLVIATGASSETQHALGTGVFGGMISATILAIFF 1012 EA + A ++RLRPILMTSLAF GV+PL I+ GA S Q+A+G GV GGM+SAT+LAIFF Sbjct: 961 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF 1020 Query: 1013 VPVFFIFV 1020 VPVFF+ + Sbjct: 1021 VPVFFVVI 1028 Score = 87.6 bits (217), Expect = 2e-19 Identities = 53/323 (16%), Positives = 125/323 (38%), Gaps = 15/323 (4%) Query: 723 IDREKLNTLGVSFASVSDIISTS---MGSMYINDFPN---QGRMQQVIVQANAKSRMHLK 776 +D + LN ++ V + + + + + P Q +I Q K+ Sbjct: 188 LDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKNPEEFG 247 Query: 777 DILSLKVAGANGQLVSLSEVV-IPQWNKLPQQYNRYNGRPSLSIAGVPNIGVSS---GDA 832 + ++G +V L +V + + R NG+P+ + G ++ A Sbjct: 248 KVTL--RVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDTAKA 305 Query: 833 MRE-MEKLIAKLPQGIGYEWT-GISLQEKQSESQMVFLIALSMLVVFLVLAALYESWSIP 890 ++ + +L PQG+ + + + S ++V + ++++VFLV+ ++ Sbjct: 306 IKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMRAT 365 Query: 891 LSVMLVVPLGIFGAVLAIMLRGMPNDIFFKIGLITIIGLSAKNAILIVE-FAKMLKEEGM 949 L + VP+ + G + G + G++ IGL +AI++VE +++ E+ + Sbjct: 366 LIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMMEDKL 425 Query: 950 TLIEAAVAAAKLRLRPILMTSLAFTCGVIPLVIATGASSETQHALGTGVFGGMISATILA 1009 EA + ++ ++ + IP+ G++ + M + ++A Sbjct: 426 PPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVA 485 Query: 1010 IFFVPVFFIFVLGAAEKLFSKKK 1032 + P +L + K Sbjct: 486 LILTPALCATLLKPVSAEHHENK 508
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 47.5 bits (113), Expect = 5e-08 Identities = 41/194 (21%), Positives = 80/194 (41%), Gaps = 23/194 (11%) Query: 60 RTAEIRPQVGGIIEKVLFAQGSEVKAGQPLYKINSETFEADVNSNRAGLNKAEAEVNRLK 119 R+ EI+P I+++++ +G V+ G L K+ + EAD ++ L +A E R + Sbjct: 95 RSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQ 154 Query: 120 I---QLERYQQL-------LPSNAISKQEV----SNVEAQYRQAIADVAQMKALLARQNL 165 I +E + +S++EV S ++ Q+ Q + L ++ Sbjct: 155 ILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRA 214 Query: 166 NLQYATVRAPISGRIGKSFVTEG------ALVSQADSNTMATIQQIDRVYVDVKQSIGEY 219 TV A I+ S V + +L+ + A + + + YV+ + Y Sbjct: 215 ERL--TVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHA-VLEQENKYVEAVNELRVY 271 Query: 220 ERLQAALQSGELSA 233 + ++S LSA Sbjct: 272 KSQLEQIESEILSA 285 Score = 44.4 bits (105), Expect = 5e-07 Identities = 40/205 (19%), Positives = 72/205 (35%), Gaps = 27/205 (13%) Query: 98 EADVNSNRAGLNKAEAEVNRLKIQLERYQQLLPSNAISKQEVSNVEAQYRQAIADVAQMK 157 ++ ++ L + E+E+ K + + QL K E+ + RQ ++ + Sbjct: 265 VNELRVYKSQLEQIESEILSAKEEYQLVTQLF------KNEIL---DKLRQTTDNIGLLT 315 Query: 158 ALLARQNLNLQYATVRAPISGRIGK-SFVTEGALVSQADSNTMATIQQIDRVYVDVKQSI 216 LA+ Q + +RAP+S ++ + TEG +V M + + D + V Sbjct: 316 LELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVV-TTAETLMVIVPEDDTLEVTALVQN 374 Query: 217 GEYERLQAALQSG-ELSANNQKAVQILNSLGQPYNVTAKMLFEDINVDPETG---DVTIR 272 + + + ++ A L K + D D G +V I Sbjct: 375 KDIGFINVGQNAIIKVEAFPYTRYGYLVG-------KVKNINLDAIEDQRLGLVFNVIIS 427 Query: 273 IEVNNPERK-----LLPGMYVRVNI 292 IE N L GM V I Sbjct: 428 IEENCLSTGNKNIPLSSGMAVTAEI 452
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 83.9 bits (207), Expect = 5e-21 Identities = 54/206 (26%), Positives = 93/206 (45%), Gaps = 10/206 (4%) Query: 5 LSNRVAIVTGAGAGLGREHALLLARLGAKVVVNDLGSDVNGKGGSTMAAQKVVDEIIAAG 64 + ++A +TGA G+G A LA GA + D + K S++ A+ Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAE---------A 56 Query: 65 GEAMANGASVTDIEQVQQMVDETISRWGRVDILINNAGILRDKTFSKMSLDDFRTVIDVH 124 A A A V D + ++ G +DIL+N AG+LR +S +++ V+ Sbjct: 57 RHAEAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVN 116 Query: 125 LMGAVNCTKAVWDIMREQKYGRIVMTTSSSGLYGNFGQSNYSAAKMALVGLMQTLALEGE 184 G N +++V M +++ G IV S+ + Y+++K A V + L LE Sbjct: 117 STGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELA 176 Query: 185 KSNVRVNCLAP-TAATRMLEGLLPEE 209 + N+R N ++P + T M L +E Sbjct: 177 EYNIRCNIVSPGSTETDMQWSLWADE 202
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 104 bits (261), Expect = 3e-29 Identities = 73/252 (28%), Positives = 116/252 (46%), Gaps = 10/252 (3%) Query: 7 GQVVLITGAASGFGALLAEQLAKYGAKLVLGDLNIEGLNTVVEPLRQVGVEVVAQVCDVS 66 G++ ITGAA G G +A LA GA + D N E L VV L+ A DV Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVR 67 Query: 67 SEADVQALVQSAVTQFGRVDVGINNAGMSPPMKSFIDTDEADLDLSFAVNAKGVFFGMKH 126 A + + + G +D+ +N AG+ P +DE + + +F+VN+ GVF + Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDE-EWEATFSVNSTGVFNASRS 126 Query: 127 QIRQMLQQGGGIILNVASVAGLGAAPKLAAYAAAKHAVVGLTKTAAIEYANKGIRVNAIC 186 + M+ + G I+ V S +AAYA++K A V TK +E A IR N + Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 187 PFYTTTPMVV------DSELKEKQDFLAQ---ASPMKRLGHPSEVVAMMLMMCAKENSYL 237 P T T M + + + L P+K+L PS++ +L + + + ++ Sbjct: 187 PGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHI 246 Query: 238 TGQAIAIDGGVT 249 T + +DGG T Sbjct: 247 TMHNLCVDGGAT 258
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 127 bits (320), Expect = 8e-38 Identities = 89/255 (34%), Positives = 124/255 (48%), Gaps = 9/255 (3%) Query: 8 LTGKIALVTGASRGIGEEIAKLLAEQGAHVIVSSRKVEDCQRVANEIIAANGKAEAFACH 67 + GKIA +TGA++GIGE +A+ LA QGAH+ E ++V + + A AEAF Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 68 VGKLEDIAAIFEYIRKEHGRLDILVNNAAANPYFGHILDTDIGAYNKTVEVNIRGYFFMS 127 V I I I +E G +DILV N A G I + T VN G F S Sbjct: 66 VRDSAAIDEITARIEREMGPIDILV-NVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNAS 124 Query: 128 VEAGKLMKKQGGGVIVNTASVNALQPGDRQGIYSITKAAVVNMTKAFAKECGPLGIRVNA 187 K M + G IV S A P Y+ +KAA V TK E IR N Sbjct: 125 RSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184 Query: 188 LLPGLTKTKFASALFENED----IYKSWMDT----IPLRRHAEPREMAGTVLYLVSDAAS 239 + PG T+T +L+ +E+ + K ++T IPL++ A+P ++A VL+LVS A Sbjct: 185 VSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAG 244 Query: 240 YTNGECIVVDGGLTI 254 + + VDGG T+ Sbjct: 245 HITMHNLCVDGGATL 259
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 60.4 bits (146), Expect = 1e-13 Identities = 32/193 (16%), Positives = 79/193 (40%), Gaps = 13/193 (6%) Query: 1 MARP---RSEDKRNAILSAAIETLAELG-ERASTSKIAKVAGVAEGTLFTYFSNKEELLN 56 MAR +++ R IL A+ ++ G S +IAK AGV G ++ +F +K +L + Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 57 QLYLSLKAELRQ-VMMLSYPTNADLQTQMSHIWQSYLDWSLEAPLKRKVMAQLSTSEQ-- 113 +++ ++ + + + D + + I L+ ++ +R +M + + Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 114 -----ITEQSKQIGMQTFCDLTQNIQERINDGKLR-DYPPLFIASILGALAEVTLNFIAQ 167 + + + + ++++ + Q ++ I L D A I+ + Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180 Query: 168 DPSQAELYRKSGF 180 P +L +++ Sbjct: 181 APQSFDLKKEARD 193
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 51.0 bits (122), Expect = 6e-10 Identities = 27/139 (19%), Positives = 53/139 (38%), Gaps = 8/139 (5%) Query: 1 MPKLKIALIDDDHARADYIRKSLLENDFEVVACLTLDHLNIFRLEHLQADVILLDMDHPH 60 M I + DDD A + ++L ++V L + D+++ D+ P Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATL-WRWIAAGDGDLVVTDVVMPD 59 Query: 61 RDIIESCVSSY-----DLPTVLFTKNSDKDTIKQAIDAGVTAYIVDGIDPARLHTILE-I 114 + + + DLP ++ + + T +A + G Y+ D L I+ Sbjct: 60 ENAFD-LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 115 SIEQYKKHKKLEGDLKEAQ 133 E ++ KLE D ++ Sbjct: 119 LAEPKRRPSKLEDDSQDGM 137
>PF04183#IucA / IucC family Length = 580 Score = 103 bits (259), Expect = 1e-25 Identities = 77/461 (16%), Positives = 155/461 (33%), Gaps = 62/461 (13%) Query: 116 ELLSLVADRPFHPFAHSK--------GELAPLTTQKEIEVYWWAFKKDDVI-NNMESIPH 166 L L++ P F + AP ++W A K++ +I + Sbjct: 128 RLQCLLSGHPKFVFNKGRRGWGKEALERYAP-EYANTFRLHWLAVKREHMIWRCDNEMDI 186 Query: 167 KELLLSEVEESLIADKMAEL-----SDDYIALPLLETQ-HRYLKFDENKY--EG--IDLN 216 +LL + ++ A +++ LP+ Q + + D EG + L Sbjct: 187 HQLLTAAMDPQEFARFSQVWQENGLDHNWLPLPVHPWQWQQKIATDFIADFAEGRMVSLG 246 Query: 217 HVTTIGLPTSSLRTLIHNTNP-TLHLKLSTNAKTLGAIRSMPGRYLMNGHTAYDFLNDVI 275 L SLRTL + + L +KL R +PGRY+ G A +L V Sbjct: 247 EFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLASRWLQQVF 306 Query: 276 NETALLKNRLFL---------SNETHWWVLGKQEPIVKNLGVIGCQVRHLPDFCQDKNVT 326 A L + + + L + + + +G R P + + Sbjct: 307 ATDATLVQSGAVILGEPAAGYVSHEGYAALARAPYRYQEM--LGVIWRENPCRWLKPDES 364 Query: 327 PITMSALSCTY------VDPW-ETLGVEGDKWSLLKDLSVHFIQTFLTLWAK-GIMPECH 378 P+ M+ L + + G++ + W L L + L + G+ H Sbjct: 365 PVLMATLMECDENNQPLAGAYIDRSGLDAETW--LTQLFRVVVVPLYHLLCRYGVALIAH 422 Query: 379 GQNTMVCYENNKFKCFVLRD-HDTLRICTTAIKESGFTPPIYT-IDTSTPNNLIFTKNED 436 GQN + + + +L+D +R+ E P + + + + D Sbjct: 423 GQNITLAMKEGVPQRVLLKDFQGDMRLVKEEFPEMDSLPQEVRDVTSRLSADYL---IHD 479 Query: 437 LFNYLITLGIQINLYPIALATLKYTDRTESDFWEMVQDIIQDFVETQSISEQTKSQIQTY 496 L G + + + E F++++ ++ D+++ Q + + Sbjct: 480 LQ-----TGHFVTVLRFISPLMVRLGVPERRFYQLLAAVLSDYMKKHP---QMSERFALF 531 Query: 497 -LFDNKTWPFKQLLTPL----LAQESDSTGMPSKIGSTPNP 532 LF + + +L P+ + S +P+ + NP Sbjct: 532 SLF--RPQIIRVVLNPVKLTWPDLDGGSRMLPNYLEDLQNP 570
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 97.6 bits (243), Expect = 2e-24 Identities = 79/389 (20%), Positives = 164/389 (42%), Gaps = 25/389 (6%) Query: 9 FIILLCQFFSTFGLMVLIPIMPLYMEKLTAHMSAPTIWAGLALAAPAIGSLFTAPIVGHL 68 +IL G+ +++P++P + L + G+ LA A+ AP++G L Sbjct: 8 IVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHY-GILLALYALMQFACAPVLGAL 66 Query: 69 SDTFGHKKALLLSLAGFCISILLMASAQHLYLFIFARILLGFCGLS-VILNAYVSYLSNE 127 SD FG + LL+SLAG + +MA+A L++ RI+ G G + + AY++ +++ Sbjct: 67 SDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDG 126 Query: 128 QQRGAAFGQLQSIVALACLCGPVLGGIFMDQWRVEILLNATAFVVMTLILIASFVLTNPV 187 +R FG + + + GPVLGG M + A A + L F+L Sbjct: 127 DERARHFGFMSACFGFGMVAGPVLGG-LMGGFSPHAPFFAAAALNGLNFLTGCFLLPESH 185 Query: 188 KTEVTKTKEKSKLP------AFFDRTIFSWLSAGILVQAGGFGLVSCFVLYISEISRSTH 241 K E + ++ P A + + ++ ++Q G + +V++ + Sbjct: 186 KGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDA 245 Query: 242 SSLSAA-SLTGTIHALSWGAAF-IAATYWGKRNDDKGDSFNNFIYASLICGITIFALI-W 298 +++ + + G +H+L+ A G+R + +I T + L+ + Sbjct: 246 TTIGISLAAFGILHSLAQAMITGPVAARLGER---------RALMLGMIADGTGYILLAF 296 Query: 299 VSNLWLILVLRLIQGFCFAALIPSILHTISLKAGAQSQGKVIGISNSAFVLGQLIGPITI 358 + W+ + ++ +P++ +S + + QG++ G + L ++GP+ Sbjct: 297 ATRGWMAFPIMVLLA-SGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLF 355 Query: 359 TLTYSFFNITAALICTSLFFIGAGLVVIL 387 T Y+ + + GA L ++ Sbjct: 356 TAIYA---ASITTWNGWAWIAGAALYLLC 381
>PF04183#IucA / IucC family Length = 580 Score = 373 bits (959), Expect = e-118 Identities = 141/598 (23%), Positives = 239/598 (39%), Gaps = 48/598 (8%) Query: 600 LAENRVMGQLLEALIFENTFKYEFSKGQIKFYISDTVFYTCAAKRHFSFKRIKLDPSSLV 659 L R++ ++L L +E F E + A+R + + +D +L Sbjct: 8 LVNRRLVAKMLSELEYEQVFHAESQGDDRYCINLPGAQWRFIAER-GIWGWLWIDAQTLR 66 Query: 660 RSDITLGTETRPNLKTLLADLKNIIEADPVKWQNFNDELNLTYVKHAQTLGQ---VPAQP 716 +D + +TLL LK ++ +L T + Q L + A Sbjct: 67 CADEPV------LAQTLLMQLKQVLSMSDATVAEHMQDLYATLLGDLQLLKARRGLSASD 120 Query: 717 LRTLPYLEQEARITNAHLYHPSFKSRIGFDLKENQKYAPELSQGFTVQWVATHNSLCKLV 776 L L + ++ H K R G+ + ++YAPE + F + W+A Sbjct: 121 LINLNADRLQCLLS-GHPKFVFNKGRRGWGKEALERYAPEYANTFRLHWLAVKREHMIWR 179 Query: 777 LSETINLEQLYKQHFSEKDLHTINDQLKEQNVDFKDYILTPIHPWQWDKIIELYYQDAIS 836 +++ QL ++ + +E +D +++ P+HPWQW + I + + Sbjct: 180 CDNEMDIHQLLTAAMDPQEFARFSQVWQENGLD-HNWLPLPVHPWQWQQKIATDFIADFA 238 Query: 837 NQLIIPLDIEGPTYLPQQSIRTLSNISDISALSLKLAMNLVNTSTSRVLAPHTVQNAAKM 896 ++ L G +L QQS+RTL+N S L +KL + + NTS R + + Sbjct: 239 EGRMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLA 298 Query: 897 SDWLYNIVEQDHILEKQRKPVILREIGGLSVNQP--IALPVQYGA----LACIWRESIYS 950 S WL + D L Q VIL E V+ AL L IWRE+ Sbjct: 299 SRWLQQVFATDATL-VQSGAVILGEPAAGYVSHEGYAALARAPYRYQEMLGVIWRENPCR 357 Query: 951 YLKEGESATPVTGLMQVDTDQKPLIDEWIQEYGI--EFWLEKLLSNAYLPIMHILWCHGL 1008 +LK ES + LM+ D + +PL +I G+ E WL +L +P+ H+L +G+ Sbjct: 358 WLKPDESPVLMATLMECDENNQPLAGAYIDRSGLDAETWLTQLFRVVVVPLYHLLCRYGV 417 Query: 1009 ALESHAQNMVLIHKNGLPVKAALKDFHDGIRFSRHLLREPNLLPNLQDAPKEHAKINPNS 1068 AL +H QN+ L K G+P + LKDF +R + P + P+E + Sbjct: 418 ALIAHGQNITLAMKEGVPQRVLLKDFQGDMRLVKE------EFPEMDSLPQEVRDVTSR- 470 Query: 1069 FLETHSPNELRDFTQDALWFVNLAELAIFLNEHYDFDEIKFWTMLRTIINQHKEAHPEFA 1128 + FV + L E +F+ +L +++ + + HP+ + Sbjct: 471 -----LSADYLIHDLQTGHFVTVLRFISPLMVRLGVPERRFYQLLAAVLSDYMKKHPQMS 525 Query: 1129 ERYELFNFTDDTIDIEQLASRRF-----------LPEIRLRVQTTPNPLSLIKEIEYE 1175 ER+ LF+ I L + LP ++ NPL L+ + EYE Sbjct: 526 ERFALFSLFRPQIIRVVLNPVKLTWPDLDGGSRMLPNY---LEDLQNPLWLVTQ-EYE 579 Score = 205 bits (522), Expect = 3e-58 Identities = 87/437 (19%), Positives = 164/437 (37%), Gaps = 49/437 (11%) Query: 128 DIANSIENTKFFLENRPSQTVTKALSGFQATEQGMLYGHPFHVTSKANLGFSKEDMKKYS 187 D+ ++ L+ R + + ++ Q +L GHP V +K G+ KE +++Y+ Sbjct: 98 DLYATLLGDLQLLKARRGLSASDLINLNADRLQCLLSGHPKFVFNKGRRGWGKEALERYA 157 Query: 188 PELGASFQLHYFAIHSSLIQKLVSEEQPSHR-----IEDEVLKTAKERLQENLA--NYEL 240 PE +F+LH+ A+ + E H+ ++ + + QEN N+ Sbjct: 158 PEYANTFRLHWLAVKREHMIWRCDNEMDIHQLLTAAMDPQEFARFSQVWQENGLDHNWLP 217 Query: 241 MPTHPWQANFLLQHPSLKKHLDSQDVIYLGVLGQTVWPTSSVRTVWLPQS--NLFLKLSI 298 +P HPWQ + ++ LG G S+RT+ L +KL + Sbjct: 218 LPVHPWQWQQKIATD-FIADFAEGRMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPL 276 Query: 299 DVRITSFIRNNPMDEMERAIDASKI---IINHKINEQYPDLMILPELEAKTVKIP----- 350 + TS R P + AS+ + +IL E A V Sbjct: 277 TIYNTSCYRGIPGRYIAAGPLASRWLQQVFATDATLVQSGAVILGEPAAGYVSHEGYAAL 336 Query: 351 -----ELESSFGILYRAGLTPEVL--ENTRMLGGLVEENENHEIPLLSIIQQAASNQNLQ 403 + G+++R + E+ ++ L+E +EN++ + L Sbjct: 337 ARAPYRYQEMLGVIWRENPCRWLKPDESPVLMATLMECDENNQ----PLAGAYIDRSGLD 392 Query: 404 SKDAKDFITFWWKQYVKVSLIPLIELFANKGISVEAHMQNSLMEFKNGYPHRLILRDMEG 463 ++ W Q +V ++PL L G+++ AH QN + K G P R++L+D +G Sbjct: 393 AET-------WLTQLFRVVVVPLYHLLCRYGVALIAHGQNITLAMKEGVPQRVLLKDFQG 445 Query: 464 ISIVPEMIEDDSSISEDSTVWFSQKDAWTFLKYYLVINHI--------AHLISAIARVTV 515 +M E ++ +D + L +I+ + IS + Sbjct: 446 -----DMRLVKEEFPEMDSLPQEVRDVTSRLSADYLIHDLQTGHFVTVLRFISPLMVRLG 500 Query: 516 IEESELWQATRLTLTQE 532 + E +Q L+ Sbjct: 501 VPERRFYQLLAAVLSDY 517
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 40.2 bits (94), Expect = 8e-07 Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 8/92 (8%) Query: 46 LPAA-PVAEAPVAKTPRGAVETSPMVGVFYAAPSPGEAPFVKVGQTVSAGETLGIIEAMK 104 LPA + E PV++ PR ++G A + +V +A L K Sbjct: 42 LPAHLELIETPVSRRPRLVAYF--IMGFLVIAF--ILSVLGQVEIVATANGKLTHSGRSK 97 Query: 105 IMNPIEATQSGVIEEILVKNGEVIQFGQPLFR 136 + PIE + +++EI+VK GE ++ G L + Sbjct: 98 EIKPIE---NSIVKEIIVKEGESVRKGDVLLK 126
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 43.3 bits (102), Expect = 1e-06 Identities = 61/323 (18%), Positives = 120/323 (37%), Gaps = 28/323 (8%) Query: 23 GVLSSIAIVTRFFAPLVWGWIADKSGKR-MLLVRIATWMESYIWLAIFIVPNTFQSVALL 81 G+L ++ + +F V G ++D+ G+R +LLV +A Y +A + L Sbjct: 46 GILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMAT--------APFLW 97 Query: 82 MLIFSFFQNAILAQFEGVTLFWLGD-----QKAKLYGKIRKWGSVGFIVGVFTIGAILEI 136 +L I V ++ D ++A+ +G + G + G +G ++ Sbjct: 98 VLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGP-VLGGLMGG 156 Query: 137 VHISMLPILLLIIASLAFIWS-FTIREPDSA---PTSQKYLEPL----LPVLKRPTVAAF 188 + L F+ F + E P ++ L PL VAA Sbjct: 157 FSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTV-VAAL 215 Query: 189 FAIEFILLFSHAPFYSFYSNFLRS-LNFSTTEIGF-LWAMGVFAEIFMFSIASKIFQRFS 246 A+ FI+ + + F ++ T IG L A G+ + I + R Sbjct: 216 MAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLG 275 Query: 247 WRSLVIVCLLVTSIRWMLVAVFSHYFIGQLFAQCLHAFSFGLFHLIAMRVIFQNFSAGQQ 306 R +++ ++ ++L+A + ++ L + G+ L AM + + +Q Sbjct: 276 ERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGMPALQAM--LSRQVDEERQ 333 Query: 307 GRGQALYSTMWGLGVAFGSVLAG 329 G+ Q + + L G +L Sbjct: 334 GQLQGSLAALTSLTSIVGPLLFT 356
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 264 bits (677), Expect = 5e-78 Identities = 140/788 (17%), Positives = 267/788 (33%), Gaps = 79/788 (10%) Query: 75 LKTLRLKMDEHIPDNQWVCINDL-NGIQFKYLENEQSLNLKVPSDMLTGYAVDLNGQQVT 133 L T + + D+ V + + + + +Q LNL +P ++ N + Sbjct: 119 LNTASVSGMNLLADDACVPLTSMIHDATAQLDVGQQRLNLTIPQAFMS------NRARGY 172 Query: 134 SPHLLKMKPLNAAILNYSLY-NTITNDENVFSGSAEGIFNSAIGNFSSGVL-------YN 185 P L +NA +LNY+ N++ N S A S + N + L YN Sbjct: 173 IPPELWDPGINAGLLNYNFSGNSVQNRIGGNSHYAYLNLQSGL-NIGAWRLRDNTTWSYN 231 Query: 186 GSNENSYSHEKWVRLESKWQYVDPEKIRIYTLGDFISNSPDWGSSVRLAGFQWSSAYSQR 245 S+ +S S KW + + + TLGD + + + G Q +S + Sbjct: 232 SSDSSSGSKNKWQHINTWLERDIIPLRSRLTLGDGYTQGDIF-DGINFRGAQLASDDNML 290 Query: 246 GDIVTSALPQFSGSAALPSTLDLYVNQQKIYSGLVPSGPFDIKQLPFISG-NEVTLVTTD 304 D P G A + + + N IY+ VP GPF I + ++ + + Sbjct: 291 PDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKE 350 Query: 305 ATGKQSITKKPYYFSSKILAKGINEFSVDVGIPRYNYGLYSNDYDDATFASGAIRYGYSN 364 A G I PY + +G +S+ G R F + +G Sbjct: 351 ADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYRSGNAQQEKPR----FFQSTLLHGLPA 406 Query: 365 SMTLSGGAEASTDGLSNLGTGFAKNVLGIGVINADIAASQYKDENGYSALLGLEGRISKN 424 T+ GG + + D G KN+ +G ++ D+ + + S G R N Sbjct: 407 GWTIYGGTQLA-DRYRAFNFGIGKNMGALGALSVDMTQANSTLPDD-SQHDGQSVRFLYN 464 Query: 425 ISFN--------TSYRKVFDNYFDLARVSQVRYLKENQINAESQNYLN------YSALAD 470 S N YR YF+ A + R N + + Y+ + Sbjct: 465 KSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYN 524 Query: 471 EIFRAGINYNFYAG-YG-VYLGYNQIKYSDNSYKLLSTNLSGSLDKNWGFYASAYKDYEN 528 + + + G +YL + Y S L+ + Sbjct: 525 KRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSNV--DEQFQAGLNTAFEDIN-------- 574 Query: 529 HKDYGVYFALRYTPSSKVNAITSVSSDSGSLRYRQEIFGLSAPQIGSFGWGGYVERDQDA 588 + + + S++ ++ + R ++ L+ I W + Q Sbjct: 575 ---WTLSY--------------SLTKNAWQ-KGRDQMLALNVN-IPFSHWLRSDSKSQWR 615 Query: 589 NENNVTSVSSDS-GSLRYRQEIFGLSEPQIGSFGWG---GYVERDQDANENNASVYASYR 644 + + S+S D G + ++G + + + + GY + + +YR Sbjct: 616 HASASYSMSHDLNGRMTNLAGVYG-TLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYR 674 Query: 645 ARAAYLTGRYNRFGDNDQVALSATGSLVAAAGRIFAANEVGEGYAVVTNAGPQSQILNGG 704 Y+ D Q+ +G ++A A + + + +V G + + Sbjct: 675 GGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQ 734 Query: 705 VNLGATDKSGRFLIANLRPYMSHHIYLDTSYLPLEWEVSSTNQTAFVGYRQGTLVDFGAH 764 TD G ++ Y + + LDT+ L ++ + +F A Sbjct: 735 -TGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKAR 793 Query: 765 QVISGLVKLVDENNSPLMPGYAVR-INDQQDGVVGYDGEVFIPNLLKQNKLEV--DLLDH 821 I L+ + NN PL G V + Q G+V +G+V++ + K++V ++ Sbjct: 794 VGIKLLM-TLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEEN 852 Query: 822 GSCQVDFA 829 C ++ Sbjct: 853 AHCVANYQ 860
>FIMBRILLIN#Porphyromonas gingivalis: fimbrillin protein signature. Length = 348 Score = 31.6 bits (71), Expect = 0.002 Identities = 19/63 (30%), Positives = 26/63 (41%), Gaps = 6/63 (9%) Query: 173 ALLNNLILVDTTANKSYPIKVN-TVNGYILAGKARNFNISPDFKFQADHKYNISLNINGK 231 A I+ D YP+ VN N Y +P K + +HKY+I L I G Sbjct: 261 AFNAGWIVADNNPTTYYPVLVNFNSNNYTYDNG-----YTPKNKIERNHKYDIKLTITGP 315 Query: 232 QTS 234 T+ Sbjct: 316 GTN 318
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 133 bits (337), Expect = 3e-36 Identities = 65/365 (17%), Positives = 121/365 (33%), Gaps = 23/365 (6%) Query: 9 DNQINPESQNYLNYSALADEIFRAGINYNFYAGYGVYLGYNQIKY-----SDNSYKL-LS 62 Q+ P+ +Y N + + + +YL + Y D ++ L+ Sbjct: 508 VIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSNVDEQFQAGLN 567 Query: 63 TNLSGSLDKNWGFYASAYKDYENHKDYGVYFALRASAYKDYENHKDYGIYFALRYTPSSK 122 T NW S K+ K AL + + D + Sbjct: 568 TAFEDI---NWTLSYSLTKN-AWQKGRDQMLALNVNIPFSHWLRSD-------SKSQWRH 616 Query: 123 VNAITSVSSDSGSLRYRQEIFGLSAPQIGSFGWG---GYVERDQDANENNASVYASYRAR 179 +A S+S D + + + + GY + + +YR Sbjct: 617 ASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGG 676 Query: 180 TAYLTGRYNRFGDNDQVAVSATGSLVAAAGRIFAANEIGDGYAVVTNAGPQSQIINGGVN 239 Y+ D Q+ +G ++A A + + D +V G + + Sbjct: 677 YGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQ-T 735 Query: 240 LGETDKSGRFLIPSLMPYQVNHVYLDPSYLPLNWNVKSTDQKTVVGYRQGTLVDFGAHQV 299 TD G ++P Y+ N V LD + L N ++ + V +F A Sbjct: 736 GVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVG 795 Query: 300 ISGLVKLVDQNNSPLMPGYTVR-INGQQNGMVGYDGEVFIPNLLKQNKLEVDLLDHGSCQ 358 I L+ + NN PL G V + Q +G+V +G+V++ + K++V + + Sbjct: 796 IKLLM-TLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAH 854 Query: 359 VDFTY 363 Y Sbjct: 855 CVANY 859
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 169 bits (430), Expect = 1e-47 Identities = 85/449 (18%), Positives = 151/449 (33%), Gaps = 45/449 (10%) Query: 62 LNISINSN--ASED--LVAVKQSKDGKLYIRSSALKTLRLKMD-----EHIPDNQWVCIN 112 ++I +N+ A+ D + + + L ++ L + D+ V + Sbjct: 80 VDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLT 139 Query: 113 DL-NGIQFKYLENEQSLNLKVPSNMLTGYSVDLSGQQVTNPHLLKMKPLNAAILNYSLYH 171 + + + +Q LNL +P ++ + P L +NA +LNY+ Sbjct: 140 SMIHDATAQLDVGQQRLNLTIPQAFMS-----NRARGYIPPELWD-PGINAGLLNYNFSG 193 Query: 172 TIT------NDENLFSGTAEGIFNSAIGNF----SSGVLYNGSNENSYSHEKWVRLESKW 221 N + G N IG + ++ YN S+ +S S KW + + Sbjct: 194 NSVQNRIGGNSHYAYLNLQSG-LN--IGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWL 250 Query: 222 QYVDPEKIRIYTLGDFISNSPDWGSSVRLAGFQWSSAYSQRGDIVTSALPQFSGSAALPS 281 + TLGD + + + G Q +S + D P G A + Sbjct: 251 ERDIIPLRSRLTLGDGYTQGDIF-DGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTA 309 Query: 282 TLDLYVNQQKIYSGLVPSGPFDIKQLPFISG-NEVTLVTTDATGQQSITKKPYYFSSKIL 340 + + N IY+ VP GPF I + ++ + +A G I PY + Sbjct: 310 QVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQ 369 Query: 341 AKGINEFSVDVGVPRYNYGLYSNDYDDATFASGAIRYGYSNSLTLSGGAEASTDGLSNLG 400 +G +S+ G R F + +G T+ GG + + D Sbjct: 370 REGHTRYSITAGEYRSGNAQQEKPR----FFQSTLLHGLPAGWTIYGGTQLA-DRYRAFN 424 Query: 401 TGFAKNVLGIGVMNADIAASQYKDENGYSALLGLEGRISKNISFN--------TSYRKVF 452 G KN+ +G ++ D+ + + S G R N S N YR Sbjct: 425 FGIGKNMGALGALSVDMTQANSTLPDD-SQHDGQSVRFLYNKSLNESGTNIQLVGYRYST 483 Query: 453 DNYFDLARVSQVRYLKDNQINPTAKYLIT 481 YF+ A + R N + Sbjct: 484 SGYFNFADTTYSRMNGYNIETQDGVIQVK 512
>PF04647#Accessory gene regulator B Length = 212 Score = 25.9 bits (57), Expect = 0.047 Identities = 15/88 (17%), Positives = 33/88 (37%), Gaps = 11/88 (12%) Query: 39 VVAVAYAFSPIDLIPDFIPILGFIDDAIILPMLIWLAVRFTPQQVIFDAEQQAEEWLDEH 98 +V A+ + P + +L I L L++L P+ +I Sbjct: 86 LVFNVLAYIAHLIDPAYFQLLILIAFITSLLALLFLVPVDNPRNLI-----------SNT 134 Query: 99 EKRPKNYLVAVLIILIWLTLAVMAYFYF 126 E+R L +++++ ++ AY + Sbjct: 135 EQRKTLKLKTSMVLMVLFGGSIGAYRLY 162
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 56.6 bits (136), Expect = 3e-12 Identities = 20/76 (26%), Positives = 36/76 (47%) Query: 1 MKVSKTQVKENREKIVEKATQLFRNKGYDGVGIAELMSSAGFTHGGFYKHFSSKTDLVSI 60 + +K + +E R+ I++ A +LF +G + E+ +AG T G Y HF K+DL S Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 61 TVKHGLEQVLKRIEGL 76 + + + Sbjct: 62 IWELSESNIGELELEY 77
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 79.3 bits (195), Expect = 1e-19 Identities = 50/185 (27%), Positives = 91/185 (49%), Gaps = 2/185 (1%) Query: 7 VLITGASSGIGSVYADRFAQRGHNLILVARDTNRLDKISKDLQEKYGVQVEFIQADLSND 66 ITGA+ GIG A A +G ++ V + +L+K+ L+ + E AD+ + Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAE-ARHAEAFPADVRDS 69 Query: 67 QDISKIEN-VLKNDADIEILVNNAGIALNGTFLTQDIKDIEKLITLNMTAVVRLSHAISQ 125 I +I + + I+ILVN AG+ G + ++ E ++N T V S ++S+ Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSK 129 Query: 126 SLRHKGKGAIINLGSVLGLAPELGSTIYGASKSFIQFFSQGLYLELKDHGVHVQAVLPSA 185 + + G+I+ +GS P Y +SK+ F++ L LEL ++ + V P + Sbjct: 130 YMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGS 189 Query: 186 TKTEI 190 T+T++ Sbjct: 190 TETDM 194
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1116 bits (2889), Expect = 0.0 Identities = 551/1031 (53%), Positives = 733/1031 (71%), Gaps = 5/1031 (0%) Query: 2 LSSFFIARPIFAWVLSICIMALGTISILTLPIEQYPDIAPPGVNVTANYPGASAKTVEDS 61 +++FFI RPIFAWVL+I +M G ++IL LP+ QYP IAPP V+V+ANYPGA A+TV+D+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 62 VTQILEQQIKGIDGLLYFSSSSSSAGQARISLSFDQNTNPDTAQVQVQNAVNQALSRLPQ 121 VTQ++EQ + GID L+Y SS+S SAG I+L+F T+PD AQVQVQN + A LPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 122 EVQQQGITVTKSQGDSLLVFALYDESGTRSSVDISDYMVSTLQDPLSRVDGVGEITVFGA 181 EVQQQGI+V KS L+V ++ + DISDY+ S ++D LSR++GVG++ +FGA Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 182 QYAMRIWLDPHKLNSYGLMPSDVRTAIEAQNTQITAGELGALPTRDGQALNATVTALSRL 241 QYAMRIWLD LN Y L P DV ++ QN QI AG+LG P GQ LNA++ A +R Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 242 QTVSQFENIILRTQTNGAVVLLKDVARVERGAESYQTSTRLNGKPASGMSIQLASGANAL 301 + +F + LR ++G+VV LKDVARVE G E+Y R+NGKPA+G+ I+LA+GANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 302 ETAERVKAEVTRLTASMPAGLKVAYPRDSTPFVEASVNGVIKTLAEAIVLVIIVMFLFLQ 361 +TA+ +KA++ L P G+KV YP D+TPFV+ S++ V+KTL EAI+LV +VM+LFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 362 SWRATLIPAIAVPVVLLGTFGVLSVLGYSINTLTLFAMVLAIGLLVDDAIVVVENVERVM 421 + RATLIP IAVPVVLLGTF +L+ GYSINTLT+F MVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 422 HEQNLDARQATLISMQEISGALVGIAMVLAAVFLPMAFFGGSVGIIYRQFSVTLVSAMVL 481 E L ++AT SM +I GALVGIAMVL+AVF+PMAFFGGS G IYRQFS+T+VSAM L Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 482 SAIVALTLSPALCATLLKPANEKHKQRK--FFTWFNYKVEQGQTGYRTKLVAVLGKPKVF 539 S +VAL L+PALCATLLKP + +H + K FF WFN + Y + +LG + Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 Query: 540 MVIFVGITALLGWQYTRMNTGFLPQEDQGSVMVQFSTPVGTTLAETERVGNQIADYFLTK 599 ++I+ I A + + R+ + FLP+EDQG + P G T T++V +Q+ DY+L Sbjct: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 Query: 600 EKNNLNVIFMVMGRNNAGSGQNVGMAFAGLKHWDDREGSENTAEAVIARANAYFKSLRNA 659 EK N+ +F V G + +G QN GMAF LK W++R G EN+AEAVI RA +R+ Sbjct: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG 660 Query: 660 RVQVLSPAAVRGLGQSSGFEFWLQDAENKGRDALLAAQNNVL-KAANADSGLAAVRLNSL 718 V + A+ LG ++GF+F L D G DAL A+N +L AA + L +VR N L Sbjct: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 Query: 719 EDKAQLQVNIDQRKASALGLAQADISNTLSSAWGGSYINDFIDQGRVKRVYLQGEAIYRS 778 ED AQ ++ +DQ KA ALG++ +DI+ T+S+A GG+Y+NDFID+GRVK++Y+Q +A +R Sbjct: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM 780 Query: 779 LPQDIGQWYVRGATGEMTPFSSFSSVKWQMGPQMLQRFNGLSAVQIQGSAAAGESSGGAM 838 LP+D+ + YVR A GEM PFS+F++ W G L+R+NGL +++IQG AA G SSG AM Sbjct: 781 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM 840 Query: 839 DKMQELVDQ-QQGFNLQWSGLSYQEKLAGGQTIWLYLASIIFIFLCLAALYESWSIPVSV 897 M+ L + G W+G+SYQE+L+G Q L S + +FLCLAALYESWSIPVSV Sbjct: 841 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900 Query: 898 MLVIPLGLIGAVVAASLAGFVNDIYFQVAMLTTIGLSAKNAILIVEFA-AAKLEAGQALM 956 MLV+PLG++G ++AA+L ND+YF V +LTTIGLSAKNAILIVEFA + G+ ++ Sbjct: 901 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV 960 Query: 957 DAIIEGAGQRLRPIIMTSLAFVAGVLPLAVSTGAGAVSRKEIGIAVTGGMISGTLLSIFF 1016 +A + RLRPI+MTSLAF+ GVLPLA+S GAG+ ++ +GI V GGM+S TLL+IFF Sbjct: 961 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF 1020 Query: 1017 VPLFFLLVRRL 1027 VP+FF+++RR Sbjct: 1021 VPVFFVVIRRC 1031
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 40.2 bits (94), Expect = 1e-05 Identities = 49/284 (17%), Positives = 91/284 (32%), Gaps = 54/284 (19%) Query: 52 QLAGRTVASEISQVRPQVNGVVIDQLFKEGTQVNKGQPLY------KIDSSLYRDSVDEA 105 +L +E V ++N + E ++++ L K + EA Sbjct: 206 ELNLDKKRAERLTVLARINRY-ENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEA 264 Query: 106 AGNLALAKATVNSTRLQAERYK-ELIKVNGVSQQELDNAQSAYEQAKATVAVNEAVLKTA 164 L + K+ + + K E V + + E Q + + L Sbjct: 265 VNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNE---ILDKLRQTTDNIGLLTLELAKN 321 Query: 165 RTNLRYTQVSAPISGRIGRSSI-TRGALVTSAQT--------EPLATIQKLDPMYVDLTQ 215 + + + AP+S ++ + + T G +VT+A+T + L + + Sbjct: 322 EERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFIN 381 Query: 216 SSDEYMALRKQLTENGIKPTELSVRLKLE--NGTAYAEQ-GTFK--FSDVAVDEATGSVT 270 + +K+E T Y G K D D+ G V Sbjct: 382 -------------------VGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVF 422 Query: 271 L-RAAFP-------NPNNALLPGLYVRAELGTGTR--LNSVLIP 304 + N N L G+ V AE+ TG R ++ +L P Sbjct: 423 NVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGMRSVISYLLSP 466 Score = 38.7 bits (90), Expect = 3e-05 Identities = 23/105 (21%), Positives = 41/105 (39%), Gaps = 4/105 (3%) Query: 55 GRTVASEISQ-VRPQVNGVVIDQLFKEGTQVNKGQPLYKIDSSLYRDSVDEAAGNLALAK 113 G+ S S+ ++P N +V + + KEG V KG L K+ + + +L A+ Sbjct: 88 GKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQAR 147 Query: 114 ATVNSTRLQAERYK-ELIKVNGVSQQELDNAQSAYEQAKATVAVN 157 R Q EL K+ + + Q+ E+ + Sbjct: 148 LEQT--RYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSL 190
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 69.3 bits (169), Expect = 1e-16 Identities = 33/172 (19%), Positives = 58/172 (33%), Gaps = 4/172 (2%) Query: 1 MLKKSPGRPSRIRPTIIAAARELFLEHGLE-VRLEAVATKAGTNRQTLYNHFPTKTALLI 59 M +K+ R I+ A LF + G+ L +A AG R +Y HF K+ L Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 60 EVFDHLKAEMEAPFIEQHELKNKSLDQLLLEIGQSVQNHFYHIDVIRLQRLLIIALVEMK 119 E+++ ++ + +E +L EI V + RL +I E Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 120 EILPKIQQR---TQGNIKRSLTDILATAHNAGIVKIDQPEEATKAFLGAVMG 168 + +QQ + L A ++ D + + Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYIS 172
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 49.2 bits (117), Expect = 1e-09 Identities = 9/65 (13%), Positives = 23/65 (35%) Query: 7 SPRAIQVVNKSIDLFHHHGFHTVGVDRIVKESQIPKATFYHYFHSKERFIEICMIVQKER 66 +++ ++ LF G + + I K + + + Y +F K + + Sbjct: 10 QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESN 69 Query: 67 LKEKV 71 + E Sbjct: 70 IGELE 74
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1035 bits (2677), Expect = 0.0 Identities = 502/1033 (48%), Positives = 682/1033 (66%), Gaps = 8/1033 (0%) Query: 2 LSKFFIQRPIFASVLAIIVMAFGIFSVLNLPVERYPDIAPPKITVSASYSGADAQTVEQS 61 ++ FFI+RPIFA VLAII+M G ++L LPV +YP IAPP ++VSA+Y GADAQTV+ + Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 62 VTQILEQQIQGIDNLLYFSSTSDSSGRSRITISFDNGTNPDTAQVQVQNSISGVIRRLPD 121 VTQ++EQ + GIDNL+Y SSTSDS+G IT++F +GT+PD AQVQVQN + LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 122 EVQRQGVTVSKSLGDTFMVVGLYDSTGKSGNIELSDYLTTHVVDDLNRIEGVGESDVFGS 181 EVQ+QG++V KS MV G + ++SDY+ ++V D L+R+ GVG+ +FG+ Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 182 QYAMRIWLNPEKLKQYNLMPSDVANAITAQNTQVAAGAIGDLPVIDGQYLNTKVTAGSRL 241 QYAMRIWL+ + L +Y L P DV N + QN Q+AAG +G P + GQ LN + A +R Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 242 KTVEDFKNIVVKANQTASYVYLKDIARVELGAENYQSFNTINGYPAAGLGISLSSGANAI 301 K E+F + ++ N S V LKD+ARVELG ENY ING PAAGLGI L++GANA+ Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 302 QTSKLIHQTLDQLTTKLPAGYKIVYPRDNTPFVQESIKEVVKTLIEAIILVILVMFLFLQ 361 T+K I L +L P G K++YP D TPFVQ SI EVVKTL EAI+LV LVM+LFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 362 SWRATLIPSITVPVVILGTFAVLYVLGFSINTLTLFALVLAIGLLVDDAIVVVENVERLM 421 + RATLIP+I VPVV+LGTFA+L G+SINTLT+F +VLAIGLLVDDAIVVVENVER+M Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 422 HEQHLTPKEAAIESMGEISGALVGITLVLTAVFIPMSFLGGSIGVIYRQFSITLVAAMAL 481 E L PKEA +SM +I GALVGI +VL+AVFIPM+F GGS G IYRQFSIT+V+AMAL Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 482 SLVVALVLTPALCALILKPNPEPM-----RWAVWFNKKIDQLKNQYIKIVQTSIRYSKSV 536 S++VAL+LTPALCA +LKP + WFN D N Y V + + Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 Query: 537 IVIFVALIAVFALFYSGLKSGFIPKEDQGILSVQIKLVDSAPISQSQKIGEQVRQYFLTQ 596 ++I+ ++A + + L S F+P+EDQG+ I+L A ++QK+ +QV Y+L Sbjct: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 Query: 597 EDKNVDLVLIRYGRNYSGTGQNLAQGFIALKPWDVRTGKENSADAIQKRAMKYFSQFRNA 656 E NV+ V G ++SG QN F++LKPW+ R G ENSA+A+ RA + R+ Sbjct: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG 660 Query: 657 QINVTLPASVNGLGQTDGLDLWIQDLNGQGQD-FLDNTFRQLQTQSKNYSSFENFDKQST 715 + ++ LG G D + D G G D + L +++ +S + Sbjct: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 Query: 716 NSKANLNIKIDQKQALANGLELPAINNTLSSAWGGTYVNDFIDRGRIKRVMIQGDAQFRS 775 A +++DQ++A A G+ L IN T+S+A GGTYVNDFIDRGR+K++ +Q DA+FR Sbjct: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM 780 Query: 776 KPEDLYNWSVRNNQNEMVPFSSFANFSWGGAPEIVKRYMGYSALQLQADVASGSSSGQAM 835 PED+ VR+ EMVPFS+F W ++RY G ++++Q + A G+SSG AM Sbjct: 781 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM 840 Query: 836 KDVEQLVNQ-QKDVGLAWTGLSFEEQKSTNQAVWLYLISAGFIFLCLAALYESLSIPAAV 894 +E L ++ +G WTG+S++E+ S NQA L IS +FLCLAALYES SIP +V Sbjct: 841 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900 Query: 895 MTSIPLGVGGSVIFSYIFGLPNDVYFQIALLTTIGLSCKNAILIVEFA-ALAQEKGKSAI 953 M +PLG+ G ++ + +F NDVYF + LLTTIGLS KNAILIVEFA L +++GK + Sbjct: 901 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV 960 Query: 954 EAALEGASLRLRPILMTSLAFGAGVIPLVFAQGAGAVSRQEIGISILGGVMFGTVLVLFF 1013 EA L +RLRPILMTSLAF GV+PL + GAG+ ++ +GI ++GG++ T+L +FF Sbjct: 961 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF 1020 Query: 1014 IPVMYVLLSSLFR 1026 +PV +V++ F+ Sbjct: 1021 VPVFFVVIRRCFK 1033
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 29.7 bits (66), Expect = 0.036 Identities = 26/168 (15%), Positives = 59/168 (35%), Gaps = 28/168 (16%) Query: 65 KFENMGAQLVREVSSKTNDIAGDGTTTATVLAQA-----ILNEGIKSVTAGMNPMDLKRG 119 ++ N G + V T+ + G T AT+ A+ IL + + P+ L Sbjct: 394 RYVNTGTAPIYNVLPTTSLVLGKNQTLATIKAKENQLSQILAPNNYYPSKNLAPIALNAQ 453 Query: 120 IDIAVKTVVENIRSNAKPADDFKAIEQVGSISANSDTTVGKLIAQAMEKVGKEGVITVEE 179 D + + N + F +E+ + ++D G + + G + V+ Sbjct: 454 DDFSSTPITMNY-------NQFLELEKTKQLRLDTDQVYGNI----ATYNFENGRVRVDT 502 Query: 180 GSGFEDALDVVEGMQ------------FDRGYISPYFANKQDTLTAEL 215 GS + + L ++ +R + ++ +T ++ Sbjct: 503 GSNWSEVLPQIQETTARIIFNGKDLNLVERRIAAVNPSDPLETTKPDM 550
>CABNDNGRPT#NodO calcium binding signature. Length = 479 Score = 43.4 bits (102), Expect = 1e-05 Identities = 28/108 (25%), Positives = 41/108 (37%), Gaps = 5/108 (4%) Query: 2755 NATGNALDNLLTGNSGNNVLNGREGNDTYMTHDGADTILFQLLNSQDATGGNGHDTVLDF 2814 NA G + +++L GNS +N+L G GND GADT L+ G+G D+ + Sbjct: 342 NAIGGSGNDILVGNSADNILQGGAGNDVLYGGAGADT-LYGGAGRDTFVYGSGQDSTVAA 400 Query: 2815 TLGDVRTDAQADKIDLSELLIDYSKDVSTLAKFITVEQDAGNTTISID 2862 DKIDLS + + + D Sbjct: 401 YDWIADFQKGIDKIDLS----AFRNEGQLSFVQDQFTGKGQEVMLQWD 444
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 30.5 bits (68), Expect = 0.028 Identities = 57/239 (23%), Positives = 88/239 (36%), Gaps = 32/239 (13%) Query: 263 NFNLKLEGQESGSRVTYLVSIDDGKTWQETTVAQKDLADGIYQFKAVITDVAGNTS-ETA 321 NF+ E G Y DG+ E K G Y+ K +TD G + E+ Sbjct: 792 NFDGTESKDEDGEIKAYEWDFGDGEKSNEAKATHKYNKTGEYEVKLTVTDNNGGINTESK 851 Query: 322 IQKVVVDTTAP------------QAGELTLSALADTGISATDQITQDKTFDLKISGQEVN 369 KVV D +A ++ S + G + + + FD+ G N Sbjct: 852 KIKVVEDKPVEVINESEPNNDFEKANQIAKSNMLVKGTLSEEDYSDKYYFDVAKKG---N 908 Query: 370 SQITYRISKDDGKTWQETTVAQKDLTDGIYQFKAILTDVAGNKSETAIQK----VVVDTT 425 +IT G TW T + DL + Y A D K E ++ + V T Sbjct: 909 VKITLNNLNSVGITW--TLYKEGDLNN--YVLYATGNDGTVLKGEKTLEPGRYYLSVYTY 964 Query: 426 ASQAGELTL-------AALTDTGISATDQITQDKTFDLKISGQEVNSQITYRISKDDGK 477 +Q+G T+ + +T A ++ + FD K + NS+I +S DD K Sbjct: 965 DNQSGTYTVNVKGNLKNEVKETAKDAIKEVENNNDFD-KAMKVDSNSKIVGTLSNDDLK 1022
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 25.9 bits (57), Expect = 0.011 Identities = 9/33 (27%), Positives = 12/33 (36%) Query: 11 AVTAGNIIVRQRGTEFHAGANVGMGRDHTLFAT 43 TAG II Q G F + + + A Sbjct: 95 VRTAGEIIGLQMGLSFATFVDPASHLNMPVLAR 127
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 47.5 bits (113), Expect = 5e-08 Identities = 39/238 (16%), Positives = 88/238 (36%), Gaps = 35/238 (14%) Query: 82 ILKRLFAEGSYVREGQALYELDSRTNRATLENAKATLLQQQANLASLRTKLNRYKQLVSS 141 L + + + A+ E +++ A E ++ L + +++ K+ Sbjct: 239 DFSSLLHKQAIAK--HAVLEQENKYVEAVNELR-----VYKSQLEQIESEILSAKEEYQL 291 Query: 142 NAVSKQEYDDLLGQVNVAEAQVSAAKAQVTNANVDLGYSTIRSPISGQSGRSSV-TAGAL 200 + ++L ++ + ++ S IR+P+S + + V T G + Sbjct: 292 VTQLFKN--EILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGV 349 Query: 201 VTANQTDPLVTIQQLDPIYVDINQSSAELLRLRQQLSKGSLNNSNNTKVKLKLE--DGST 258 VT +T +V + + D + V + ++ + + +K+E + Sbjct: 350 VTTAET-LMVIVPEDDTLEVTALVQNKDIGFINVGQN-----------AIIKVEAFPYTR 397 Query: 259 YP-IEGQLA--FSDASVNQDTGTIT--LRAVFSN------PNHLLLPGMYTTAQIVQG 305 Y + G++ DA +Q G + + ++ N N L GM TA+I G Sbjct: 398 YGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTG 455 Score = 42.1 bits (99), Expect = 3e-06 Identities = 26/130 (20%), Positives = 58/130 (44%), Gaps = 8/130 (6%) Query: 56 VEQSVELSGR-TSAYQISEVRPQTSGVILKRLFAEGSYVREGQALYELDSRTNRATLENA 114 VE +G+ T + + E++P + ++ + + EG VR+G L +L + A Sbjct: 80 VEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKT 139 Query: 115 KATLLQQQANLASLRT-----KLNRYKQLVSSNAVSKQ--EYDDLLGQVNVAEAQVSAAK 167 +++LLQ + + +LN+ +L + Q +++L ++ + Q S + Sbjct: 140 QSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQ 199 Query: 168 AQVTNANVDL 177 Q ++L Sbjct: 200 NQKYQKELNL 209
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 755 bits (1952), Expect = 0.0 Identities = 384/673 (57%), Positives = 500/673 (74%), Gaps = 5/673 (0%) Query: 1 MAQFFIHRPIFAWVIALVIMLAGILTLTKMPIAQYPTIAPPTVTIAATYPGASAETVENT 60 MA FFI RPIFAWV+A+++M+AG L + ++P+AQYPTIAPP V+++A YPGA A+TV++T Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQIIEQQMNGLDGLRYISSNSAGNGQASIQLNFEQGIDPDIAQVQVQNKLQSATALLPE 120 VTQ+IEQ MNG+D L Y+SS S G +I L F+ G DPDIAQVQVQNKLQ AT LLP+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 DVQRQGVTVTKSGASFLQVIAFYSPDNSLSDSDIKDYVNSSIKEPLSRVAGVGEVQVFGG 180 +VQ+QG++V KS +S+L V F S + + DI DYV S++K+ LSR+ GVG+VQ+FG Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 SYAMRIWLDPAKLTSYQLTPSDIATALQAQNSQVAVGQLGGAPAVQGQVLNATVNAQSLL 240 YAMRIWLD L Y+LTP D+ L+ QN Q+A GQLGG PA+ GQ LNA++ AQ+ Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 QTPEQFKNIFLKNTASGAEVRLKDVARVELGSDNYQFDSKFNGKPAGGLAIKIATGANAL 300 + PE+F + L+ + G+ VRLKDVARVELG +NY ++ NGKPA GL IK+ATGANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 DTAEAVEHRLSELRKNYPTGLADKLAYDTTPFIRLSIESVVHTLIEAVVLVFIVMFLFLQ 360 DTA+A++ +L+EL+ +P G+ YDTTPF++LSI VV TL EA++LVF+VM+LFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NWRATIIPTLAVPVVVLGTFAVINIFGFSINTLTMFAMVLAIGLLVDDAIVVVENVERVM 420 N RAT+IPT+AVPVV+LGTFA++ FG+SINTLTMF MVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 SEEHTDPVTATSRSMQQISGALIGITSVLTAVFVPMAFFGGTTGVIYRQFSITLVTAMVL 480 E+ P AT +SM QI GAL+GI VL+AVF+PMAFFGG+TG IYRQFSIT+V+AM L Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SLIVALTFTPALCATILKQHDPNKAPSNNIFARFFRGFNNGFDRMSHSYQNGVNRMLKGK 540 S++VAL TPALCAT+LK P A + FF FN FD + Y N V ++L Sbjct: 481 SVLVALILTPALCATLLK---PVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGST 537 Query: 541 IFSGVLYAVVIALLVFLFQKLPSSFLPEEDQGVVMTLVQLPPNATLDRTGKVIDTMTNFF 600 ++YA+++A +V LF +LPSSFLPEEDQGV +T++QLP AT +RT KV+D +T+++ Sbjct: 538 GRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYY 597 Query: 601 M-NEKDTVESIFTVSGFSFTGVGQNAGIGFVKLKDWSERTSPETQIGALIQRGMALNMIV 659 + NEK VES+FTV+GFSF+G QNAG+ FV LK W ER E A+I R + Sbjct: 598 LKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKI 657 Query: 660 KDASYIMPLQLPA 672 +D +++P +PA Sbjct: 658 RDG-FVIPFNMPA 669 Score = 97.2 bits (242), Expect = 7e-23 Identities = 82/510 (16%), Positives = 184/510 (36%), Gaps = 40/510 (7%) Query: 5 FIHRPIFAWVIALVIMLAGILTLTKMPIAQYPTIAPPTVTIAATYP-GASAETVENTVTQ 63 + +I +I+ ++ ++P + P P GA+ E + + Q Sbjct: 533 ILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQ 592 Query: 64 IIEQQMNGLDGLRY---------ISSNSAGNGQASIQL-NFEQGIDPDIAQVQVQNKLQS 113 + + + S + G A + L +E+ + + V ++ + Sbjct: 593 VTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKM 652 Query: 114 ATALLPE------DVQRQGVTVTKSGASF-LQVIAFYSPDNSLSDSDIKDYVNSSIKEPL 166 + + ++ T +G F L A D ++ + + Sbjct: 653 ELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALT---QARNQLLGMAAQHP 709 Query: 167 SRVAGVGEVQVFGGSYAMRIWLDPAKLTSYQLTPSDIATALQAQNSQVAVGQLGGAPAVQ 226 + + V + + ++ +D K + ++ SDI + V + Sbjct: 710 ASLVSVRPNGLEDTAQ-FKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDF----IDR 764 Query: 227 GQVLNATVNA-QSLLQTPEQFKNIFLKNTASGAEVRLKDVARVELGSDNYQFDSKFNGKP 285 G+V V A PE +++++ A+G V + + ++NG P Sbjct: 765 GRVKKLYVQADAKFRMLPEDVDKLYVRS-ANGEMVPFSAFTTSHWVYGSPRL-ERYNGLP 822 Query: 286 AGGLAIKIATGANALDTAEAVEHRLSELRKNYP---TGLADKLAYDTTPFIRLSIESVVH 342 + + + A G ++ D +E+ S+L TG++ + RLS Sbjct: 823 SMEIQGEAAPGTSSGDAMALMENLASKLPAGIGYDWTGMSYQE--------RLSGNQAPA 874 Query: 343 TLIEAVVLVFIVMFLFLQNWRATIIPTLAVPVVVLGTFAVINIFGFSINTLTMFAMVLAI 402 + + V+VF+ + ++W + L VP+ ++G +F + M ++ I Sbjct: 875 LVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTI 934 Query: 403 GLLVDDAIVVVENVERVMSEEHTDPVTATSRSMQQISGALIGITSVLTAVFVPMAFFGGT 462 GL +AI++VE + +M +E V AT +++ ++ + +P+A G Sbjct: 935 GLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGA 994 Query: 463 TGVIYRQFSITLVTAMVLSLIVALTFTPAL 492 I ++ MV + ++A+ F P Sbjct: 995 GSGAQNAVGIGVMGGMVSATLLAIFFVPVF 1024
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 431 bits (1110), Expect = e-145 Identities = 219/364 (60%), Positives = 276/364 (75%), Gaps = 13/364 (3%) Query: 1 MQLKDSSGQGHEKLIAARNTILGLAAQD-KRLVGVRPNGQEDTPQYQINVDQAQAGAMGV 59 +L D +G GH+ L ARN +LG+AAQ LV VRPNG EDT Q+++ VDQ +A A+GV Sbjct: 681 FELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGV 740 Query: 60 SIAEINNTMRIAWGGSYINDFVDRGRVKKVYVQGDAGSRMMPEDLNKWYVRNNKGEMVPF 119 S+++IN T+ A GG+Y+NDF+DRGRVKK+YVQ DA RM+PED++K YVR+ GEMVPF Sbjct: 741 SLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPF 800 Query: 120 SAFATGEWTYGSPRLERYNGVSSVNIQGTPAPGVSSGDSMKAMEEIIDKLPSMGLQGFDY 179 SAF T W YGSPRLERYNG+ S+ IQG APG SSGD+M ME + KLP G Y Sbjct: 801 SAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASKLP----AGIGY 856 Query: 180 EWTGLSLEERESGAQAPFLYALSLLIVFLCLAALYESWSIPFSVLLVVPLGIIGAIVLTY 239 +WTG+S +ER SG QAP L A+S ++VFLCLAALYESWSIP SV+LVVPLGI+G ++ Sbjct: 857 DWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAAT 916 Query: 240 LGMIIKGDPNLSNNIYFQVAMIAVIGLSAKNAILIVEFAKELQEK-GEDLIEATLHAAKM 298 L N N++YF V ++ IGLSAKNAILIVEFAK+L EK G+ ++EATL A +M Sbjct: 917 LF-------NQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRM 969 Query: 299 RLRPIIMTTLAFGFGVLPLALSTGAGAGSQHSVGYGVLGGVLSATFLGIFFIPVFYVWIR 358 RLRPI+MT+LAF GVLPLA+S GAG+G+Q++VG GV+GG++SAT L IFF+PVF+V IR Sbjct: 970 RLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIR 1029 Query: 359 SIFK 362 FK Sbjct: 1030 RCFK 1033 Score = 68.7 bits (168), Expect = 1e-14 Identities = 52/333 (15%), Positives = 116/333 (34%), Gaps = 18/333 (5%) Query: 33 GVRPNGQEDTPQYQINVDQAQAGAMGVSIAEINNTMRIA----WGGSYINDFVDRGRVKK 88 V+ G + +I +D ++ ++ N +++ G G+ Sbjct: 174 DVQLFGAQY--AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLN 231 Query: 89 VYVQGDAGSRMMPEDLNKWYVRNNK-GEMVPFSAFATGEWTYGSPR-LERYNGVSSVNIQ 146 + + PE+ K +R N G +V A E + + R NG + + Sbjct: 232 ASIIAQTRFKN-PEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLG 290 Query: 147 GTPAPGVSSGDSMKAMEEIIDKLPSMGLQGFDYEWT-GLSLEERESGAQAPFLYALSLLI 205 A G ++ D+ KA++ + +L QG + + + S + ++++ Sbjct: 291 IKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIML 350 Query: 206 VFLCLAALYESWSIPFSVLLVVPLGIIGAIVLTYLGMIIKGDPNLSNNIYFQVAMIAVIG 265 VFL + ++ + VP+ ++G + S N M+ IG Sbjct: 351 VFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAA-------FGYSINTLTMFGMVLAIG 403 Query: 266 LSAKNAILIVE-FAKELQEKGEDLIEATLHAAKMRLRPIIMTTLAFGFGVLPLALSTGAG 324 L +AI++VE + + E EAT + ++ + +P+A G+ Sbjct: 404 LLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGST 463 Query: 325 AGSQHSVGYGVLGGVLSATFLGIFFIPVFYVWI 357 ++ + + + + P + Sbjct: 464 GAIYRQFSITIVSAMALSVLVALILTPALCATL 496
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.8 bits (67), Expect = 0.028 Identities = 24/166 (14%), Positives = 53/166 (31%), Gaps = 28/166 (16%) Query: 78 DLRTATLNIERAQQQYRITQNNQLPTIGASGSAIRQVSQSRDPNNPYSTYQVGLGVTAYE 137 L A L R Q R + N+LP + Q + Sbjct: 142 SLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVL---------------- 185 Query: 138 LDFWGRVRSLKDAALDSYLSTQSARDSTQISLISQVAQAWLNYSFATANLRLAEQTLKAQ 197 R+ SL ++ Q+ + +++L + A+ A + E + + Sbjct: 186 -----RLTSLIKEQFSTW---QNQKYQKELNLDKKRAER----LTVLARINRYENLSRVE 233 Query: 198 QDSYNLNKKRFDVGIDSEVPLRQAQISVETARNDVANYKTQIAQAQ 243 + + ++ + + + A N++ YK+Q+ Q + Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIE 279
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 89.3 bits (221), Expect = 2e-23 Identities = 54/189 (28%), Positives = 98/189 (51%), Gaps = 1/189 (0%) Query: 7 LQNKVVWITGASSGLGKALAGELALQGAKLILTSRRFEELEEVRVGL-LNPDHHLSVVAD 65 ++ K+ +ITGA+ G+G+A+A LA QGA + E+LE+V L H + AD Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 66 ITDEKQVQEAYKQILKAKGRIDWLINNAGLSQRALIKDTTMATERAIMEVDYFSQVALTK 125 + D + E +I + G ID L+N AG+ + LI + A V+ ++ Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 126 TVLPTMLKQKSGRVVFVSSVAGLLGTQYRASYSAAKAAIHMWANSLRAEVSDQGVEVSVI 185 +V M+ ++SG +V V S + A+Y+++KAA M+ L E+++ + +++ Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 186 FPGFVKTNV 194 PG +T++ Sbjct: 186 SPGSTETDM 194
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 83.7 bits (207), Expect = 2e-18 Identities = 28/113 (24%), Positives = 54/113 (47%), Gaps = 2/113 (1%) Query: 1378 IMIVDDSVTVRKVTSRLLERQGYDVVTAKDGVDAIEQLENIKPDLMLLDIEMPRMDGFEV 1437 I++ DD +R V ++ L R GYDV + + DL++ D+ MP + F++ Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 1438 LNLVRHHDLHQDMPVIMITSRTGEKHRERAFTLGVNQYMGKPFQEEDLLHNID 1490 L ++ +PV++++++ +A G Y+ KPF +L+ I Sbjct: 66 LPRIKKARPD--LPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>FLAGELLIN#Flagellin signature. Length = 507 Score = 30.0 bits (67), Expect = 0.031 Identities = 22/228 (9%), Positives = 63/228 (27%), Gaps = 10/228 (4%) Query: 451 STAMNEMAQSIDQVSSNASESAEVAERSVQIASNGAQVVNRSIEGMDTIREQIQETSKRI 510 + + + Q S NA++ +A Q +N +++ + + Q + Sbjct: 50 ANRFTSNIKGLTQASRNANDGISIA----QTTEGALNEINNNLQRVRELSVQATNGTNSD 105 Query: 511 KRLGESSQEIGNIVSLINDIADQT-----NILALNAAIQASMAGEAGRGFAVVADEVQRL 565 L EI + I+ +++QT +L+ + ++ + G + ++ Sbjct: 106 SDLKSIQDEIQQRLEEIDRVSNQTQFNGVKVLSQDNQMKIQVGANDGETITIDLQKIDVK 165 Query: 566 AERSASATKQIETLV-KTIQTDTNEAVISMEQTTTEVVRGANLAKDAGIALDEIQKVSGD 624 + + + V + + + D D Sbjct: 166 SLGLDGFNVNGPKEATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPD 225 Query: 625 LANLIASISDAAKLQSASASHIATTMTVVQEITSQTTTATFDTARSVS 672 + A+ + + + + T + A + Sbjct: 226 KVYVNAANGQLTTDDAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGK 273
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 84.1 bits (208), Expect = 2e-22 Identities = 39/118 (33%), Positives = 58/118 (49%), Gaps = 2/118 (1%) Query: 2 ARILIVDDSPTETFRFKEILTKHGYDVLEASNGADGVTLAKAEQPDLVLMDVVMPGVNGF 61 A IL+ DD + L++ GYDV SN A A DLV+ DVVMP N F Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 QATRQITRDEDTKHIPVVIVSTKDQATDRVWGKRQGAIDYLIKPIEENQLIDVIKQFL 119 +I + +PV+++S ++ + +GA DYL KP + +LI +I + L Sbjct: 64 DLLPRI-KKAR-PDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 78.7 bits (194), Expect = 2e-20 Identities = 31/118 (26%), Positives = 55/118 (46%), Gaps = 2/118 (1%) Query: 9 KVMVIDDSKTIRRTAETLLQREGCEVITAVDGFEALSKIAEANPDIVFVDIMMPRLDGYQ 68 ++V DD IR L R G +V + IA + D+V D++MP + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 69 TCALIKNSQNYQNIPVIMLSSKDGLFDQAKGRVVGSDEYLTKPFSKDELLNAIRNHVS 126 IK + ++PV+++S+++ K G+ +YL KPF EL+ I ++ Sbjct: 65 LLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 51.0 bits (122), Expect = 4e-09 Identities = 37/217 (17%), Positives = 73/217 (33%), Gaps = 49/217 (22%) Query: 99 RLNNQDNVARLAQARANLASAQSQAELARNLMNRKQRLFNQGFIARVEF---EQSQVDYK 155 LN A A + ++ + + ++ ++ L ++ IA+ E V+ Sbjct: 206 ELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAV 265 Query: 156 GQLESVKAQ-------------------------------QANVDIA------KKADQDG 178 +L K+Q Q +I K ++ Sbjct: 266 NELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQ 325 Query: 179 ---IITSPISGVIIKRQV-EPGQTVSVGQTLFEIV-NPDQLEIQAKLPIEQQAALKIGSN 233 +I +P+S + + +V G V+ +TL IV D LE+ A + + + +G N Sbjct: 326 QASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQN 385 Query: 234 IQYQI----QGNSKQLNATLTRISPVADQDSRQIEFF 266 ++ L + I+ A +D R F Sbjct: 386 AIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVF 422 Score = 39.0 bits (91), Expect = 2e-05 Identities = 22/116 (18%), Positives = 44/116 (37%), Gaps = 10/116 (8%) Query: 52 GALDSQTAFTGTIRAVQQS-SIQAQVSATATNVTANVGQQVQKGQVLVRLNNQDNVARLA 110 G ++ G + +S I+ ++ + G+ V+KG VL++L Sbjct: 78 GQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTA-------L 130 Query: 111 QARANLASAQSQAELARNLMNRKQRLFNQGFIARVEFEQSQVDYKGQLESVKAQQA 166 A A+ QS AR R Q L I + + ++ + ++V ++ Sbjct: 131 GAEADTLKTQSSLLQARLEQTRYQILSRS--IELNKLPELKLPDEPYFQNVSEEEV 184
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 779 bits (2014), Expect = 0.0 Identities = 284/1026 (27%), Positives = 489/1026 (47%), Gaps = 34/1026 (3%) Query: 1 MMMLSLMVLGLASWKRMTVEEFPNIDFPFVVVTTQYAGASPEAVESDITKKLEDQINTIS 60 ++ + LM+ G + ++ V ++P I P V V+ Y GA + V+ +T+ +E +N I Sbjct: 14 VLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQVIEQNMNGID 73 Query: 61 GIKQITSRS-SEGLSMVIAEFNLDTSSAIAAQDVRDKIAPVTAQFRDEIDTPIVQRYDPS 119 + ++S S S G + F T IA V++K+ T E+ + S Sbjct: 74 NLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQQQGISVEKSS 133 Query: 120 SSPIMSVVFESNSMSLAQ--LSSYVDKKIVPQLKTVSGVGNVNLLGDAKRQIRIKVIPAQ 177 SS +M F S++ Q +S YV + L ++GVG+V L G A+ +RI + Sbjct: 134 SSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG-AQYAMRIWLDADL 192 Query: 178 LQSYGIGIDQVINTLKNENIEVPAGTL------QQKNSELVVQIQSKVIHPLAFGDLVI- 230 L Y + VIN LK +N ++ AG L + + Q++ +P FG + + Sbjct: 193 LNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKNPEEFGKVTLR 252 Query: 231 ANKNGSPIFLKQVATVEDTQAELQSSAFYNGRTAVSVDILKSSDANVIKVVDQTYQTLEK 290 N +GS + LK VA VE A NG+ A + I ++ AN + L + Sbjct: 253 VNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDTAKAIKAKLAE 312 Query: 291 LKDQMPAGLDYKVVADSSKGIRASIKDVVRTIIEGAALAVLIVLLFLGSFRSTVITGLTL 350 L+ P G+ D++ ++ SI +VV+T+ E L L++ LFL + R+T+I + + Sbjct: 313 LQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAV 372 Query: 351 PITLLGTLTFIWAFGFSINMMTLLALSLSIGLLIDDAIVVRENIVRH-TELGKDHVTAAL 409 P+ LLGT + AFG+SIN +T+ + L+IGLL+DDAIVV EN+ R E A Sbjct: 373 PVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATE 432 Query: 410 EGTKEIGLAVLATTLTIVAVFLPVAFMGGLIGRFFYQFGVTVSTAVLISMFISFTLDPML 469 + +I A++ + + AVF+P+AF GG G + QF +T+ +A+ +S+ ++ L P L Sbjct: 433 KSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPAL 492 Query: 470 SAHWKDPVKKKD-NWLQRFFNHISNLLDRLTHVYEKLLKLALRFRFITVIVAIASLFAAL 528 A PV + FF + D + Y + L +++ + + Sbjct: 493 CATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLLIYALIVAGMV 552 Query: 529 GLSKLIGTEFVPTPDKGEVRIQFETPVDSSLEYTQAKLHQVDQII--RQFPDVVSTYGVV 586 L + + F+P D+G + P ++ E TQ L QV + +V S + V Sbjct: 553 VLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNEKANVESVFTVN 612 Query: 587 NSEVDSGKNHAGLG-VTLKPKQERSSDLNTLNNEFRDRLQTVAGIRVTSVAAAQDS---- 641 +AG+ V+LKP +ER+ D N+ + IR V Sbjct: 613 GFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGFVIPFNMPAIVE 672 Query: 642 --VSGGQKPIMISIKGSDLNELQKISDRFIAEMEK-INGVVDLESSLKEPKPTLGVHINR 698 + G +I G + L + ++ + + +V + + E + +++ Sbjct: 673 LGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQ 732 Query: 699 VLASDLGLSVSQIANAIRPLIAGDNVTTWEDRDGETYDVNLRLNENKRMLPQDVQNLYIN 758 A LG+S+S I I + G V + D G + ++ + RMLP+DV LY+ Sbjct: 733 EKAQALGVSLSDINQTISTALGGTYVNDFID-RGRVKKLYVQADAKFRMLPEDVDKLYV- 790 Query: 759 SNKTNAAGQNILVPLSAVATTEEKLGASQINRRDLEREVLIEAN-TSGRPSGDIGQDIDK 817 +A G+ +VP SA T+ G+ ++ R + + I+ G SGD ++ Sbjct: 791 ---RSANGE--MVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMALMEN 845 Query: 818 MQKAFKLPAGYTFDTQGANADMAESAGYALTAITLSIVFIYIVLGSQFNSFIHPAAIMAS 877 + KLPAG +D G + S A + +S V +++ L + + S+ P ++M Sbjct: 846 LAS--KLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLV 903 Query: 878 LPLSLIGVFLALFLFQSTLNLFSIIGIIMLMGLVTKNAILLIDFIKKAMD-QGVSRYDAI 936 +PL ++GV LA LF +++ ++G++ +GL KNAIL+++F K M+ +G +A Sbjct: 904 VPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEAT 963 Query: 937 LQAGKTRLRPILMTTSAMVMGMVPLALGLGEGGEQSAPMAHAVIGGVITSTLLTLVVVPV 996 L A + RLRPILMT+ A ++G++PLA+ G G + V+GG++++TLL + VPV Sbjct: 964 LMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPV 1023 Query: 997 IFTYLD 1002 F + Sbjct: 1024 FFVVIR 1029
>PF06580#Sensor histidine kinase Length = 349 Score = 26.4 bits (58), Expect = 0.013 Identities = 9/51 (17%), Positives = 17/51 (33%), Gaps = 7/51 (13%) Query: 11 ILGWKF--VLIVGVLSAIFLGFFYLAMSNEPDYMPGAQRKAQQEQMQQKAE 59 L F V++ + S Y +Y + + M Q+A+ Sbjct: 117 ALSIIFNVVVVTFMWSL-----LYFGWHFFKNYKQAEIDQWKMASMAQEAQ 162
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 34.1 bits (78), Expect = 7e-05 Identities = 16/60 (26%), Positives = 27/60 (45%), Gaps = 3/60 (5%) Query: 65 SVGRVAVLMPYRKQGIGKILMQHIIDYARRHKLPYLKLSAQTYVTA---FYEALGFYVQG 121 + +AV YRK+G+G L+ I++A+ + L L Q + FY F + Sbjct: 91 LIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGA 150
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 32.1 bits (73), Expect = 0.004 Identities = 69/376 (18%), Positives = 131/376 (34%), Gaps = 50/376 (13%) Query: 64 LATFAIA-FIARPIGAALFGHLGDRIGRKATLVAALLTMGISTVCIGLLPTYAQIGIVAP 122 LA +A+ F P+ G L DR GR+ L+ +L + + P Sbjct: 49 LALYALMQFACAPVL----GALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLW------- 97 Query: 123 LLLAVCRLGQGLGLGGEWSGAVLLATENAPEGKRA-WYGMFPQLGAPIGFILATGSFL-- 179 +L + R+ G+ G + A + +RA +G + A GF + G L Sbjct: 98 -VLYIGRIVAGIT-GATGAVAGAYIADITDGDERARHFGF---MSACFGFGMVAGPVLGG 152 Query: 180 LLSAVIPEQAFMQWGWRIPFIASAVLVIVG-LYIRLKLHETPAFQKVLDKQKEVN--IPF 236 L+ P PF A+A L + L L E+ ++ +++ +N F Sbjct: 153 LMGGFSP---------HAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASF 203 Query: 237 KEVLTKHTGKLILGTVAAICTF-----VVFYLTTVFALNWGTTKLGYARGEFLELQLFAT 291 + ++ + ++ + +W T +G + L F Sbjct: 204 RWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGIS------LAAFGI 257 Query: 292 LCFAAFIPLSAIFAEKFGRKTTSIGVCISAAIFGLFFSSMLESG-NTLIVFLFLCTGLAI 350 L A ++ A + G + + + + A G + G + + L +G Sbjct: 258 LHSLAQAMITGPVAARLGERRA-LMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIG 316 Query: 351 MGLTYGPIGTVLSELFPTSVRYTGSALTFNLAGIFGASFAPLIATKLAETYGLYAVGYYL 410 M + + E ++ + +ALT +L I G PL+ T + G+ Sbjct: 317 MPALQAMLSRQVDEERQGQLQGSLAALT-SLTSIVG----PLLFTAIYAASITTWNGWAW 371 Query: 411 TAASLLSLVAFLLIRE 426 A + L L+ +R Sbjct: 372 IAGAALYLLCLPALRR 387
>SECA#SecA protein signature. Length = 901 Score = 1217 bits (3151), Expect = 0.0 Identities = 532/909 (58%), Positives = 679/909 (74%), Gaps = 12/909 (1%) Query: 1 MLASLIGGIFGTKNERELKRMRKIVEQINALEPTISALSDADLSAKTPEFKQRYNNGESL 60 ML L+ +FG++N+R L+RMRK+V INA+EP + LSD +L KT EF+ R GE L Sbjct: 1 MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVL 60 Query: 61 DKLLPEAFAVCREAAKRVMGMRHYDVQLIGGITLHEGKIAEMRTGEGKTLMGTLACYLNA 120 + L+PEAFAV REA+KRV GMRH+DVQL+GG+ L+E IAEMRTGEGKTL TL YLNA Sbjct: 61 ENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNA 120 Query: 121 LSGQGVHVITVNDYLAQRDAELNRPLFEFLGLSIGTIYSMQGPSEKAEAYLADITYGTNN 180 L+G+GVHV+TVNDYLAQRDAE NRPLFEFLGL++G K EAY ADITYGTNN Sbjct: 121 LTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNN 180 Query: 181 EFGFDYLRDNMVFSLAEKKQRGLHYAIIDEVDSILIDEARTPLIISGQSEDSSHLYSAIN 240 E+GFDYLRDNM FS E+ QR LHYA++DEVDSILIDEARTPLIISG +EDSS +Y +N Sbjct: 181 EYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVN 240 Query: 241 TIPPKLHPQK---EEKVADGGHFWIDEKQRSVEMTEIGYETVEQELIQMGLLAEGESLYS 297 I P L Q+ E GHF +DEK R V +TE G +E+ L++ G++ EGESLYS Sbjct: 241 KIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYS 300 Query: 298 ATNLNLVHHVSAAIRAHFLFQRDVHYIIHDGEVVIVDEHTGRTMPGRRWSEGLHQAVEAK 357 N+ L+HHV+AA+RAH LF RDV YI+ DGEV+IVDEHTGRTM GRRWS+GLHQAVEAK Sbjct: 301 PANIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAK 360 Query: 358 EGLEIQPENQTLATTTFQNYFRLYKKLSGMTGTADTEAAEMKEIYGLDVVIIPTHRPMIR 417 EG++IQ ENQTLA+ TFQNYFRLY+KL+GMTGTADTEA E IY LD V++PT+RPMIR Sbjct: 361 EGVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIR 420 Query: 418 NDQNDLIYLNRNGKYNAIIQEIMNIRGQGVAPILIGTATIEASEILSSKLMQAGIHHEVL 477 D DL+Y+ K AII++I +G P+L+GT +IE SE++S++L +AGI H VL Sbjct: 421 KDLPDLVYMTEAEKIQAIIEDIKERTAKG-QPVLVGTISIEKSELVSNELTKAGIKHNVL 479 Query: 478 NAKQHEREADIIAQAGSPNAVTIATNMAGRGTDIILGGNWKAKLAKLENPTAEDEARLKA 537 NAK H EA I+AQAG P AVTIATNMAGRGTDI+LGG+W+A++A LENPTAE ++KA Sbjct: 480 NAKFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKA 539 Query: 538 QWEQDHEDVLQAGGLHIIGSERHESRRIDNQLRGRAGRQGDPGVSRFYLSLEDDLMRIFA 597 W+ H+ VL+AGGLHIIG+ERHESRRIDNQLRGR+GRQGD G SRFYLS+ED LMRIFA Sbjct: 540 DWQVRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFA 599 Query: 598 GDRVVGMMRAMGLKEDEAIEHKMVSRSIENAQRKVEARNFDIRKNLLKYDDVNNEQRKII 657 DRV GMMR +G+K EAIEH V+++I NAQRKVE+RNFDIRK LL+YDDV N+QR+ I Sbjct: 600 SDRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAI 659 Query: 658 YSQRDEVLAENTLKEYVEEMHREVMQGMIANFIPPESIHDQWDVEGLENALRIDLGIELP 717 YSQR+E+L + + E + + +V + I +IPP+S+ + WD+ GL+ L+ D ++LP Sbjct: 660 YSQRNELLDVSDVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLP 719 Query: 718 IQEWLDQDRRLDEEGLVERISDEVIERYRQRRAQMGDESAAMLERHFVLNSLDRHWKDHL 777 I EWLD++ L EE L ERI + IE Y+++ +G E E+ +L +LD WK+HL Sbjct: 720 IAEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHL 779 Query: 778 AAMDYLRQGIHLRGYAQKNPEQEYKKEAFNLFVNMLGIIKTDVVTDLSRVHIPTPEELAE 837 AAMDYLRQGIHLRGYAQK+P+QEYK+E+F++F ML +K +V++ LS+V + PEE+ E Sbjct: 780 AAMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEE 839 Query: 838 MEAQQQQQAESMKLSFEHDDVDGLTGEVTLSQETMNESADQQAFPVPESRNAPCPCGSGL 897 +E Q++ +AE + + + + + ++ +++ RN PCPCGSG Sbjct: 840 LEQQRRMEAERLA---QMQQLSHQDDDSAAAAALAAQTGERKV-----GRNDPCPCGSGK 891 Query: 898 KYKQCHGKI 906 KYKQCHG++ Sbjct: 892 KYKQCHGRL 900
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.9 bits (75), Expect = 0.004 Identities = 14/47 (29%), Positives = 23/47 (48%), Gaps = 1/47 (2%) Query: 573 VVGDGKIRAPMDGAVVN-ILVNKGDQVIKGQTLLVLEAMKIQQQIKS 618 G K P++ ++V I+V +G+ V KG LL L A+ + Sbjct: 92 HSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLK 138 Score = 29.8 bits (67), Expect = 0.040 Identities = 13/64 (20%), Positives = 29/64 (45%), Gaps = 12/64 (18%) Query: 579 IRAPMDGAVVNILVNKGDQVIK-GQTLLVL----EAMKIQQQIKS-DVDGVVDDVLGQQG 632 IRAP+ V + V+ V+ +TL+V+ + +++ +++ D+ + G Sbjct: 330 IRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFI------NVG 383 Query: 633 QQVK 636 Q Sbjct: 384 QNAI 387
>RTXTOXINC#Gram-negative bacterial RTX toxin-activating protein C signature. Length = 170 Score = 29.5 bits (66), Expect = 0.008 Identities = 21/98 (21%), Positives = 39/98 (39%), Gaps = 25/98 (25%) Query: 22 GSILYLWLNRPESRN----AMNLNMVNAIQ--QVFAAIRNDLSIRAVIIRGEGGTFCAGG 75 G + +LW + P RN +N++ AIQ Q R+D + +C+ Sbjct: 11 GHVSWLWASSPLHRNWPVSLFAINVLPAIQANQYVLLTRDDYPV----------AYCSWA 60 Query: 76 D---------IKDMATLRVEAANVGSLQPYVDFNRRFG 104 + + D+ +L E G + ++D+ FG Sbjct: 61 NLSLENEIKYLNDVTSLVAEDWTSGDRKWFIDWIAPFG 98
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 106 bits (266), Expect = 2e-29 Identities = 64/257 (24%), Positives = 111/257 (43%), Gaps = 17/257 (6%) Query: 20 KVIIVTGGGSGIGRCTAHELAALGAQVVITGRKIEKLEKVSQEIIEDGGLVHFIVCDNRE 79 K+ +TG GIG A LA+ GA + EKLEKV + + D R+ Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 80 EEQVKNMIAEVIEKFGKLDGLVNNAGGQFPSALENISANGFDAVVRNNLHATFYLMREAY 139 + + A + + G +D LVN AG P + ++S ++A N F R Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 140 NQWMAKHGGSIVNMTADMWGGMP--GMGHSGAARSGVDNLTKTASVEWGKSGVRVNAVAP 197 M + GSIV + ++ G+P M ++++ TK +E + +R N V+P Sbjct: 129 KYMMDRRSGSIVTVGSNP-AGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 198 G----------WIVSSGMDNYSGDFAKVIIPSLAGNVPLKRMGTESEVSSAICYLLSDAA 247 G W +G + + + +PLK++ S+++ A+ +L+S A Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLE----TFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 248 AFVSGVTLRIDGAASQG 264 ++ L +DG A+ G Sbjct: 244 GHITMHNLCVDGGATLG 260
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 67.0 bits (163), Expect = 6e-16 Identities = 29/132 (21%), Positives = 55/132 (41%), Gaps = 1/132 (0%) Query: 20 RGRLLQGAAYLFHKQGYDKTTVRELAQFIGIQSGSLFHHFKSKDDILAHVMEQTIIYNLA 79 R +L A LF +QG T++ E+A+ G+ G+++ HFK K D+ + + E + Sbjct: 13 RQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGE 72 Query: 80 RLAEAAAQ-STDPEHQLRALIKAELISITGDTGAAMAVLVYEWFALSKEKQDYLLEMRNE 138 E A+ DP LR ++ L S + + + + + + + + Sbjct: 73 LELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRN 132 Query: 139 YEQIWLDVIEKL 150 D IE+ Sbjct: 133 LCLESYDRIEQT 144
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 32.4 bits (73), Expect = 0.007 Identities = 17/78 (21%), Positives = 36/78 (46%), Gaps = 9/78 (11%) Query: 642 QLLLDCQQILKQSLFDPAYIDFNFLEQTLAQIQ---SLTTHEHFSENYTLVLKQISLLLE 698 LL Q+ ++ + ID NF+++ L + Q SL +F+ ++ VL+ + Sbjct: 206 SDLLFSQKFKEKLELNNKSIDINFIKENLTEFQHAFSLAFSYYFAPDHRTVLELYA---- 261 Query: 699 TLPELLTLKDKLLEQEIK 716 P++ +KL + + Sbjct: 262 --PDMFEYMNKLEKGGFE 277
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 50.2 bits (120), Expect = 7e-09 Identities = 43/175 (24%), Positives = 69/175 (39%), Gaps = 8/175 (4%) Query: 13 TLMFPLALVLFEFAVYIGNDLIQPAMLAITEDFGVSATWAPSS---MSFYLLGGASVAWL 69 L+ L+ V + +G LI P + + D S ++ Y L + A + Sbjct: 6 PLIVILSTVALDA---VGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPV 62 Query: 70 LGPLSDRLGRKKVLLAGALFFALCCFLILLTTQIEQFLALRFLQGIGLTVISAVGYAAIQ 129 LG LSDR GR+ VLL A+ ++ + R + GI + G A I Sbjct: 63 LGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAG-AYIA 121 Query: 130 ESFAERDAIKVMALMANISLLAPLLGPVLGAFLIDYVSWHWGFVAIAVLALLSWI 184 + + + M+ + GPVLG + S H F A A L L+++ Sbjct: 122 DITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFAAAALNGLNFL 175
>FRAGILYSIN#Fragilysin metallopeptidase (M10C) enterotoxin signature. Length = 405 Score = 26.2 bits (57), Expect = 0.039 Identities = 17/57 (29%), Positives = 29/57 (50%), Gaps = 8/57 (14%) Query: 2 MKKNGLLIIF-SLSILTACAPPQNSSAQLADSPIQAVL----LDQPDL---LNDASN 50 MK LL++ + ++L AC+ +S D+P+ A + + DL LND S+ Sbjct: 9 MKNVKLLLMLGTAALLAACSNEADSLTTSIDAPVTASIDLQSVSYTDLATQLNDVSD 65
>PF05860#haemagglutination activity domain. Length = 117 Score = 26.3 bits (58), Expect = 0.026 Identities = 8/29 (27%), Positives = 14/29 (48%) Query: 48 AQPEIVKEHNNTSVQQVFNRVESPTVSRI 76 +N T++Q + +RV +VS I Sbjct: 44 PTSGTAFFNNPTNIQNIISRVTGGSVSNI 72
>PF05272#Virulence-associated E family protein Length = 892 Score = 27.7 bits (61), Expect = 0.029 Identities = 13/36 (36%), Positives = 19/36 (52%), Gaps = 4/36 (11%) Query: 23 LVGPMGAGKTTVGRHLAELLGREFLDSDHEIERKTG 58 L G G GK+T+ + L+G +F SD + TG Sbjct: 601 LEGTGGIGKSTL---INTLVGLDFF-SDTHFDIGTG 632
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 234 bits (598), Expect = 1e-69 Identities = 96/434 (22%), Positives = 176/434 (40%), Gaps = 57/434 (13%) Query: 304 DVPWDQALDIILKTKNLDKRRNGNVIWIAPVAELIKAEEEEAKAVAQSVKLAPLQTEYIQ 363 + W A D++ L+K + + + + VA ++ E A V+ I+ Sbjct: 198 PLSWASAADVVKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSGEPNSRQRIIAMIK 257 Query: 364 ----------------LKYAQAQDIMSLITQGSNNSNGLQRTSGGGTSTSTNLNTGVDSL 407 LKYA+A D++ ++T S+ +Q + L Sbjct: 258 QLDRQQATQGNTKVIYLKYAKASDLVEVLTGISST---MQSEKQAAKPVAA--------L 306 Query: 408 GNNVGSLLSPRGTITQDDRTNTLIINDTAQSIDQIRKMIDLLDVQVKQVMVEARIVRAST 467 N+ I +TN LI+ ++ + ++I LD++ QV+VEA I Sbjct: 307 DKNI--------IIKAHGQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQD 358 Query: 468 SFTKELGVKWGILSQGITNNNNLLVGGSETTLWNLREPKKDETTGGYKYTIERPDNLNVD 527 + LG++W + G+T N + S + K + Sbjct: 359 ADGLNLGIQWANKNAGMTQFTNSGLPISTAIAGANQYNKDGTVSSSL------------- 405 Query: 528 LGVTNPAGSIAFGLISMSDFMLDLELSALQADGYGEVISTPKVMTADKQPAKVATGQQVP 587 + IA G + + L+AL + ++++TP ++T D A GQ+VP Sbjct: 406 ASALSSFNGIAAGFYQGN---WAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVP 462 Query: 588 YQTTTNSAAGATASTS--FKDALLSLDVTPSITPDGKIQMKLDISKDSV----SGAAPNG 641 T + + +G + K + L V P I + ++++ SV S + + Sbjct: 463 VLTGSQTTSGDNIFNTVERKTVGIKLKVKPQINEGDSVLLEIEQEVSSVADAASSTSSDL 522 Query: 642 ELILNKNNIKTNVLVNNGETVILGGVFEQTTLNSQTKVPFFGDLPGIGRLFRKDQKSDDK 701 N + VLV +GETV++GG+ +++ ++ KVP GD+P IG LFR K K Sbjct: 523 GATFNTRTVNNAVLVGSGETVVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSK 582 Query: 702 QELLIFVTPRIVND 715 + L++F+ P ++ D Sbjct: 583 RNLMLFIRPTVIRD 596 Score = 41.8 bits (98), Expect = 8e-06 Identities = 30/213 (14%), Positives = 74/213 (34%), Gaps = 37/213 (17%) Query: 260 SGNKLSLDFQDIEVRRVLQLLADFTGINMVAADSVQGNITLRLKD-VPWDQALDI---IL 315 + + S F+ +++ + ++ ++ SV+G IT+R D + +Q +L Sbjct: 26 AAEEFSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRSYDMLNEEQYYQFFLSVL 85 Query: 316 KTKNLDKRRNGNVIWIAPVAELIKAEEEEAKAVAQSVKLAPLQTEYIQLKYAQAQDIMSL 375 N + ++ K + A + T + L A+D+ L Sbjct: 86 DVYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIGDEVVTRVVPLTNVAARDLAPL 145 Query: 376 ITQGSNNSNGLQRTSGGGTSTSTNLNTGVDSLGNNVGSLLSPRGTITQDDRTNTLIINDT 435 + Q ++N + G++ + +N L++ Sbjct: 146 LRQLNDN---------------------------------AGVGSVVHYEPSNVLLMTGR 172 Query: 436 AQSIDQIRKMIDLLDVQVKQVMVEARIVRASTS 468 A I ++ +++ +D + +V + AS + Sbjct: 173 AAVIKRLLTIVERVDNAGDRSVVTVPLSWASAA 205
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 28.6 bits (64), Expect = 0.034 Identities = 34/156 (21%), Positives = 61/156 (39%), Gaps = 34/156 (21%) Query: 183 ILDIGHTMTTLSVMQNGKIIYTREQVFGGKQLTLEI----QSRYGLSLEE--AGRAKKE- 235 ++DIG T ++V+ ++Y+ GG + I + YG + E A R K E Sbjct: 163 VVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEI 222 Query: 236 -RSLPDD--YDIEI-----------------------LEPFLDAVVQQAARSLQFFFSSS 269 + P D +IE+ L+ L +V +L+ Sbjct: 223 GSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPEL 282 Query: 270 QFNEIDH-ILLAGGNANIPGLAKLLQQKLGYRVTIA 304 + + ++L GG A + L +LL ++ G V +A Sbjct: 283 ASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVA 318
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 28.2 bits (62), Expect = 0.044 Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 4/62 (6%) Query: 210 ELKQEQIIDAPFVLDQQALKNLIAMTP----YAYKASPERRSQLEQQSQLEITASFQIYV 265 E KQ+ I+D L+ Q + N + P Y Y +PE+RS+ S++ +F + Sbjct: 370 EEKQKIILDQAKALETQYVHNALKRNPVPRNYNYYQAPEKRSKHIMPSEIFDDGTFTYFG 429 Query: 266 FQ 267 F+ Sbjct: 430 FK 431
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 94.7 bits (235), Expect = 5e-25 Identities = 55/177 (31%), Positives = 90/177 (50%), Gaps = 2/177 (1%) Query: 13 VQDKVILVTGASSGIGLTISNKLADAGAHVLLVARTQETLEEVKADIEKRGGKASIFPCD 72 ++ K+ +TGA+ GIG ++ LA GAH+ V E LE+V + ++ A FP D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 73 LNDMDMIDQVSKEILATVDHIDILINNAGRSIRRAVHESYDRFHDFERTMQLNYFGAVRL 132 + D ID+++ I + IDIL+N AG +H D ++E T +N G Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSD--EEWEATFSVNSTGVFNA 123 Query: 133 VLNILPHMIQRKDGQIINISSIGVLANATRFSAYVASKAALDAFSRCLSAEVHAHKI 189 ++ +M+ R+ G I+ + S T +AY +SKAA F++CL E+ + I Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNI 180
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 94.9 bits (236), Expect = 1e-24 Identities = 37/133 (27%), Positives = 71/133 (53%), Gaps = 3/133 (2%) Query: 1 MVDDDVRLRTLLQRFLEDKGFVVKTAHDASQMDRLLQRELFSLIVLDFMLPVEDGLSICR 60 + DDD +RT+L + L G+ V+ +A+ + R + L+V D ++P E+ + Sbjct: 8 VADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDLLP 67 Query: 61 RLRQSNIDTPIIMLTARGSDSDRIAGLEAGADDYLPKPFNPNELLARIRAVL---RRQVR 117 R++++ D P+++++A+ + I E GA DYLPKPF+ EL+ I L +R+ Sbjct: 68 RIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPS 127 Query: 118 EVPGAPSQQVEVV 130 ++ + +V Sbjct: 128 KLEDDSQDGMPLV 140
>PF06580#Sensor histidine kinase Length = 349 Score = 32.9 bits (75), Expect = 0.002 Identities = 19/108 (17%), Positives = 35/108 (32%), Gaps = 29/108 (26%) Query: 340 LDIQFEMQDVPIIPARSLSLKRLIANLINNAKRYGAEP------IELSAKVENECILITV 393 I + DV + P L+ L+ N ++G I L +N + + V Sbjct: 244 NQINPAIMDVQVPPM-------LVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEV 296 Query: 394 ADHGEGIPADQIEELMQPFVRGDSARTIQGSGLGLAIVKRIVDIHHGE 441 + G + E +G GL V+ + + +G Sbjct: 297 ENTGSLALKNTKE----------------STGTGLQNVRERLQMLYGT 328
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 27.6 bits (61), Expect = 0.014 Identities = 16/95 (16%), Positives = 37/95 (38%), Gaps = 3/95 (3%) Query: 32 ETDIFRKVSQQDDLFLVAIKDEQLIG--TLMGGYDGHRGWINYLAVHPHQQRLGIATALV 89 + V ++ + + IG + ++G I +AV ++ G+ TAL+ Sbjct: 53 DDMDVSYVEEEGKAAFLYYLENNCIGRIKIRSNWNG-YALIEDIAVAKDYRKKGVGTALL 111 Query: 90 QQLEKRLIARGCPKLQLLVRKDNLNVLNFYEQLGY 124 + + L L + N++ +FY + + Sbjct: 112 HKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 31.8 bits (72), Expect = 4e-04 Identities = 19/114 (16%), Positives = 32/114 (28%), Gaps = 10/114 (8%) Query: 21 ERLYDTSPEFGDGHDAIEQLEQDLQQYTTLYTAEFNTKIIGAI-WSSGQGESKVLEYIVV 79 E + P F D + ++ + IG I S ++E I V Sbjct: 39 EERFS-KPYFKQYEDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRSNWNGYALIEDIAV 97 Query: 80 HPANRGRGVAERLVEEACRIEESKGVKTFE--------PGCGAIHRCLAHIGKL 125 R +GV L+ +A + C + IG + Sbjct: 98 AKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGAV 151
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 28.6 bits (64), Expect = 0.012 Identities = 4/31 (12%), Positives = 15/31 (48%) Query: 128 QRPTPGWERVLGWIYIILIPLALVFAVVATI 158 + P R++ + + + +A + +V+ + Sbjct: 50 ETPVSRRPRLVAYFIMGFLVIAFILSVLGQV 80
>PF04619#Dr-family adhesin Length = 160 Score = 29.1 bits (65), Expect = 0.013 Identities = 31/134 (23%), Positives = 51/134 (38%), Gaps = 9/134 (6%) Query: 3 MKKLGL--ATAVLLAMTGAHAYQFEVQGQSEYVDTTANDKNFTGDVAGTFYLKNVDTAKG 60 MKKL + A +++ A++ AHA F G + T T + V +G Sbjct: 1 MKKLAIMAAASMVFAVSSAHA-GFTPSGTTGTTKLTV-----TEECQVRVGDLTVAKTRG 54 Query: 61 PLAEAAFLNQASSVSLGYSYQQYD-QNNGLNYHVGTYGVKGYVPTPYLPVYASATYNHTD 119 L +AA + + +LG +Q + + N+ G + + L V T N Sbjct: 55 QLTDAAPIGPVTVQALGCDARQVALKADTDNFEQGKFFLISDNNRDKLYVNIRPTDNSAW 114 Query: 120 VDGKNNFSKDDNGD 133 F K+D G Sbjct: 115 TTDNGVFYKNDVGS 128
>SECYTRNLCASE#Preprotein translocase SecY subunit signature. Length = 437 Score = 29.3 bits (66), Expect = 0.047 Identities = 11/64 (17%), Positives = 27/64 (42%), Gaps = 4/64 (6%) Query: 236 LIIFVSILASLSVFLGLDKGVKRLSELNLVLALILLVFVFIAGPSIYLLQTT----IQNT 291 +++F+SI A+ L K L+ + ++ V + + +++ Q +Q Sbjct: 192 ILMFISIAATFPSALWAIKKQGTLAGGWIEFGTVIAVGLIMVALVVFVEQAQRRIPVQYA 251 Query: 292 GQYI 295 + I Sbjct: 252 KRMI 255
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 52.9 bits (127), Expect = 6e-09 Identities = 17/89 (19%), Positives = 38/89 (42%), Gaps = 3/89 (3%) Query: 1047 RILCLDNDETILEGMSSLLGRWGYEVFKATEPEQALEIIQKENIQVWLIDQHLNNNQLGV 1106 IL D+D I ++ L R GY+V + I + + + D + ++ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVM-PDENAF 63 Query: 1107 DFI--LQNRQHDVPVALITADSHPELPQQ 1133 D + ++ + D+PV +++A + + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIK 92
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 72.9 bits (179), Expect = 3e-17 Identities = 31/118 (26%), Positives = 54/118 (45%), Gaps = 3/118 (2%) Query: 3 ILIVDDHPLFRHALIQAVRYSLPQAQIHETASVDEFYERLENGAEPDLVLLDLNLPGASG 62 IL+ DD R L QA+ S + T++ + + G + DLV+ D+ +P + Sbjct: 6 ILVADDDAAIRTVLNQAL--SRAGYDVRITSNAATLWRWIAAG-DGDLVVTDVVMPDENA 62 Query: 63 FSALVYVRAQYPSIPIIVVSAHEETSIIQRAIAHGAMGYIPKSAHPSHIGEAIRQVLE 120 F L ++ P +P++V+SA +A GA Y+PK + + I + L Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 73.9 bits (181), Expect = 1e-17 Identities = 51/194 (26%), Positives = 89/194 (45%), Gaps = 3/194 (1%) Query: 2 KNFKNKVAAITGAGSGIGQQLAILLAKQGCHLSLSDINEKGLQQTVELLKPYNNITVTTK 61 K + K+A ITGA GIG+ +A LA QG H++ D N + L++ V LK Sbjct: 4 KGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEAR-HAEAF 62 Query: 62 KLDVSDREAVKQWAQETVQDHGSVNLIFNNAGVALGSTVEGATYEDLEWIVGINFWGVVY 121 DV D A+ + ++ G ++++ N AGV + + E+ E +N GV Sbjct: 63 PADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 122 GTKEFLPFIKQTQDGHIINISSLFGLTAQPTQSGYNATKFAVRGFTESLRQELDIEKSGV 181 ++ ++ + G I+ + S + + + Y ++K A FT+ L EL + + Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLEL--AEYNI 180 Query: 182 SSLCVHPGGIRTNI 195 V PG T++ Sbjct: 181 RCNIVSPGSTETDM 194
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 62.3 bits (151), Expect = 5e-14 Identities = 25/175 (14%), Positives = 62/175 (35%), Gaps = 5/175 (2%) Query: 27 SERKEARREKLIEAGIATYGTLGFFSVTVKDVCQEAKLTERYFYESFKKSEDLFQTIFLK 86 + + R+ +++ + + G S ++ ++ + A +T Y FK DLF I+ Sbjct: 6 KQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWEL 65 Query: 87 MIEELQQNLMQAVIKAAPDPEKMVDAGLRALLTTLKDDPRLARIVYVDAVLVQELHNQAT 146 + + ++ K DP ++ L +L + + R ++ + + + A Sbjct: 66 SESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAV 125 Query: 147 IQETLAQFD-RMIQAFVMLTMPQIQHHE----NELSLIATGLNGYVTQIAIRWVM 196 +Q+ I+ A + GY++ + W+ Sbjct: 126 VQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 82.2 bits (203), Expect = 3e-20 Identities = 32/123 (26%), Positives = 60/123 (48%), Gaps = 3/123 (2%) Query: 6 ILIVDDELPIREMIHTSLDMAGFQCLQAEDAKQAHQIIVDQRPALILLDWMLPGGVSGVD 65 IL+ DD+ IR +++ +L AG+ +A + I L++ D ++P + D Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE-NAFD 64 Query: 66 LCRRLKRDENLAEIPVIMLTARGEEDHKVQGLDAGADDYMTKPFSTRELVSRIKAVLRRA 125 L R+K+ ++PV++++A+ ++ + GA DY+ KPF EL+ I L Sbjct: 65 LLPRIKKAR--PDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 126 NAL 128 Sbjct: 123 KRR 125
>PF06580#Sensor histidine kinase Length = 349 Score = 30.6 bits (69), Expect = 0.014 Identities = 20/103 (19%), Positives = 34/103 (33%), Gaps = 25/103 (24%) Query: 347 LITNAIKY----TPKGGTITIGWHDDGEHAYFSVQDTGIGINPKHLPRLTERFYRVDSDR 402 L+ N IK+ P+GG I + D V++TG Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALK----------------- 305 Query: 403 SRQTGGTGLGLAIVKH---VLMQHGAYLDVQSKENEGSTFTAV 442 TG GL V+ +L A + + K+ + + + Sbjct: 306 -NTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLI 347
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 46.4 bits (110), Expect = 1e-07 Identities = 82/408 (20%), Positives = 139/408 (34%), Gaps = 27/408 (6%) Query: 1 MNTQSNTAFSLLALAIGAFAIGTTEFSPMGLLPNIANDLGISIPTA---GMLITGYALGV 57 M L +A+ A IG M +LP + DL S G+L+ YAL Sbjct: 1 MKPNRPLIVILSTVALDAVGIGLI----MPVLPGLLRDLVHSNDVTAHYGILLALYALMQ 56 Query: 58 MLGAPFMTLWFGGFARRNALILLMAIFTVGNLIAAFSPSYMSLLGARLITSLNHGAFFGI 117 AP + F RR L++ +A V I A +P L R++ + Sbjct: 57 FACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVA 116 Query: 118 GSVVAASIVPAHKQASAVATMFMGLTIANIGGVPLATWVGQNIGWRMSFLAISLLGVITM 177 G+ + A I ++A M + G L +G F A + L + Sbjct: 117 GAYI-ADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFAAAALNGLNF 174 Query: 178 LALWKALP-------QGMVAQKPNVKAELKVLTRTPVVLALLTTVLGAGAMFTLYTYIAP 230 L LP + + + N A + VV AL+ + + + Sbjct: 175 LTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWV 234 Query: 231 SLTEFT-HASPTFITFMLVLIGVGFSIGN-HLGGRFADLSINKTLIGFLVLLIVMMVTFP 288 E H T I L G+ S+ + G A + + ++ +I + Sbjct: 235 IFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRAL--MLGMIADGTGYI 292 Query: 289 ILAQSQIGAAIALVIWGAATFALVPPLQMRVMS--VAHEAPGLASSVNIGAFNLGNAVGA 346 +LA + G ++ A+ + P ++S V E G +L + VG Sbjct: 293 LLAFATRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGP 352 Query: 347 AAGALVLDLGWGYSAVSFAG-ALLAGLGLLLVLFQIKRESSPAQALQQ 393 + + S ++ G A +AG L L+ R + A Q+ Sbjct: 353 LLFTAI----YAASITTWNGWAWIAGAALYLLCLPALRRGLWSGAGQR 396
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 26.6 bits (58), Expect = 0.032 Identities = 18/85 (21%), Positives = 26/85 (30%), Gaps = 9/85 (10%) Query: 14 IMSSVAFAEPAIQPEDTLESLSKARITTNVNTQTAT-PTAQTSDANAEVKVE-------- 64 + A A P+ E E+ + T N Q AT TAQ + E K Sbjct: 1024 PVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTN 1083 Query: 65 DIDPIIGETIAEAPKAAVQAEAVAA 89 ++ ET + V Sbjct: 1084 EVAQSGSETKETQTTETKETATVEK 1108
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 478 bits (1232), Expect = e-154 Identities = 232/1065 (21%), Positives = 452/1065 (42%), Gaps = 76/1065 (7%) Query: 5 LSEWALNNKGIVLYFMLLLGIIGAISYSKLSQSEDPPFTFKVMVVQTYWPGATAKEVSTL 64 ++ + + ++L + GA++ +L ++ P + V +PGA A+ V Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 65 VTDRIEKELMTTGQYDKIMAYSRPGESMVTFVAKDSLTSAQIPDVWYNVRKKVNDIRHEL 124 VT IE+ + + + S S+ + S T I V V+ K+ L Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQV--QVQNKLQLATPLL 118 Query: 125 PNGVQGP-FFNDEFGDTFGNIYVLTGKDFDYAL--LKEYADR-LQLQLQRVKDVSKVELI 180 P VQ ++ ++ + + + +Y ++ L R+ V V+L Sbjct: 119 PQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLF 178 Query: 181 GLQDQKIWVEISNTKAVQLGIPVTAIQEALQKQNSMASAGFFETGTD------RIQIRVS 234 G Q + + + + + + L+ QN +AG I Sbjct: 179 GAQYA-MRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQ 237 Query: 235 GHLQNIDEIKKTPLLVGD--KTIQLGDVADVYRGFSQPAQPRMRFMGENGIGIAVSMRKG 292 +N +E K L V ++L DVA V G + R G+ G+ + + G Sbjct: 238 TRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGG-ENYNVIARINGKPAAGLGIKLATG 296 Query: 293 GDIIALGKNLETEFAQLQKTLPLGMKLQKVSDQPVAVQRSIHEFVKVLAEAVIIVLLVSF 352 + + K ++ + A+LQ P GMK+ D VQ SIHE VK L EA+++V LV + Sbjct: 297 ANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMY 356 Query: 353 FSLG-FRTGLVVAFSIPLVLAMTFAGMSLFDVGLHKISLGALILALGLLVDDAIIAVEMM 411 L R L+ ++P+VL TFA ++ F ++ +++ ++LA+GLLVDDAI+ VE + Sbjct: 357 LFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENV 416 Query: 412 A-IKMEQGYSRIKAAGFAWKTTAFPMLTGTLITAAGFLPIATAQSSTGEYTRSIFQVVTI 470 + ME +A + ++ ++ +A F+P+A STG R + Sbjct: 417 ERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVS 476 Query: 471 ALLVSWIAAVLFVPYLGEKLLPDFTKLGHQAP-----WYVRLWARLTKKPQPQTVAISQD 525 A+ +S + A++ P L LL + H+ W+ + Sbjct: 477 AMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVN------------ 524 Query: 526 HHYDPYQSNFYLRFRKMVEFCVTYRKTVIATTVGIFVLSVLMFKLVPQQFFPPSNRAEIL 585 H+ + R ++ + I V++F +P F P ++ L Sbjct: 525 HYTNSVGKILGSTGRYLLIY------------ALIVAGMVVLFLRLPSSFLPEEDQGVFL 572 Query: 586 VDLKLEEGASLTATEQAVKKVENFLSKQKGIDNYVAYVGTGSPRFYLPLDQQLPQASFAQ 645 ++L GA+ T++ + +V ++ K + + + G + Q Q + Sbjct: 573 TMIQLPAGATQERTQKVLDQVTDYYLKNEKANVESVFTVNG----FSFSGQ--AQNAGMA 626 Query: 646 FVVLASSLDDRDDIRRSLETQIKQL---LPQVRTRVSLLENGPPV-------GYPLQYRV 695 FV L ++R+ S E I + L ++R + N P + G+ + Sbjct: 627 FVSL-KPWEERNGDENSAEAVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELID 685 Query: 696 SGEDLNLVRKEA-QQVAKVMSENPNT-TNVHLDWGEPSKIISIQIDQDRARQMGVSSLDL 753 + +A Q+ + +++P + +V + E + +++DQ++A+ +GVS D+ Sbjct: 686 QAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDI 745 Query: 754 ANFINASITGSAIEQYREKRELIEIRLRGDQAERVEVASLASLAVPTNNGTTVPLAQIAK 813 I+ ++ G+ + + ++ + ++ ++ D R+ + L V + NG VP + Sbjct: 746 NQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTT 805 Query: 814 IEYKFEDGLIWHRNRLPTITVRADIRTNLQPATVVGELAESMDKLRAELPSGYLIEVGGT 873 + + + N LP++ ++ P T G+ M+ L ++LP+G + G Sbjct: 806 SHWVYGSPRLERYNGLPSMEIQG----EAAPGTSSGDAMALMENLASKLPAGIGYDWTGM 861 Query: 874 VEESARGQDSVNAGMPLFLAVVMTLLMIQLKSLSRSTIVLLTAPLGLIGVVLFLLLFNKP 933 + + A + + VV L +S S V+L PLG++GV+L LFN+ Sbjct: 862 SYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQK 921 Query: 934 FGFVAMLGTIALSGMIMRNSLILIDQIEQ-DRQAGHPTWEAIIEATVRRFRPIILTALAA 992 M+G + G+ +N++++++ + + G EA + A R RPI++T+LA Sbjct: 922 NDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAF 981 Query: 993 VLAMIPLSRSIFFG-----PMAVAIMGGLIVATLLTLFFLPALYA 1032 +L ++PL+ S G + + +MGG++ ATLL +FF+P + Sbjct: 982 ILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFV 1026 Score = 89.1 bits (221), Expect = 5e-20 Identities = 76/522 (14%), Positives = 175/522 (33%), Gaps = 51/522 (9%) Query: 542 MVEFCVTYRKTVIATTVGIFVLSVLMFKLVPQQFFPPSNRAEILVDLKLEEGASLTATEQ 601 M F + + + + L +P +P + V + T + Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 602 AVKKVENFLSKQKGIDN---YVAYVGTGSPRFYLPLDQQLPQASFAQFVVLASSLDDRDD 658 + +E ++ + G+ + A + Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIA--------------QVQ 106 Query: 659 IRRSLETQIKQLLPQVRTRVSLLENGPPVGYPLQYRVSGEDLNLVRKE-----AQQVAKV 713 ++ L+ LLPQ + + Y + ++ + + A V Sbjct: 107 VQNKLQ-LATPLLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDT 165 Query: 714 MSENPNTTNVHLDWGEPSKIISIQIDQDRARQMGVSSLDLANFI---NASITGSAI--EQ 768 +S +V L + + I +D D + ++ +D+ N + N I + Sbjct: 166 LSRLNGVGDVQLFGAQ--YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTP 223 Query: 769 YREKREL-IEIRLRGDQAERVEVASLASLAVPTNNGTTVPLAQIAKIEYKFEDGLIWHR- 826 ++L I + E + +G+ V L +A++E E+ + R Sbjct: 224 ALPGQQLNASIIAQTRFKNPEEFGKVTLRVNS--DGSVVRLKDVARVELGGENYNVIARI 281 Query: 827 NRLPTITVRADIRTNLQPATVVGELAESMDKLRAELPSGYLIEV----GGTVEESARGQD 882 N P + + T + + +L+ P G + V+ S Sbjct: 282 NGKPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIH--- 338 Query: 883 SVNAGMPLFLAVVMTLLMIQ--LKSLSRSTIVLLTAPLGLIGVVLFLLLFNKPFGFVAML 940 LF A+++ L++ L+++ + I + P+ L+G L F + M Sbjct: 339 --EVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMF 396 Query: 941 GTIALSGMIMRNSLILIDQIEQDRQAGH-PTWEAIIEATVRRFRPIILTALAAVLAMIPL 999 G + G+++ +++++++ +E+ P EA ++ + ++ A+ IP+ Sbjct: 397 GMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPM 456 Query: 1000 -----SRSIFFGPMAVAIMGGLIVATLLTLFFLPALYAAWFK 1036 S + ++ I+ + ++ L+ L PAL A K Sbjct: 457 AFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLK 498
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 47.1 bits (112), Expect = 6e-08 Identities = 28/175 (16%), Positives = 55/175 (31%), Gaps = 18/175 (10%) Query: 66 VGGQVTARYVDVGDRVKVGQVLAKLDVADAQLQLNAAKAQLDNAQASA------KTAADE 119 V V G+ V+ G VL KL A+ ++ L A+ + + Sbjct: 103 ENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIEL 162 Query: 120 LKRFQQLLPINAVSRS--------QFDTVKNQYDAAQAALQQARSNYE-VSANQTGYNQL 170 K + LP ++ +K Q+ Q Q N + A + Sbjct: 163 NKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLAR 222 Query: 171 VSNKNGVITARNIEIG---QVIAAGQAAYQLAIDGEREVVIGVPEQAVTEIKVGQ 222 ++ + + ++ A ++ E + V V E V + ++ Q Sbjct: 223 INRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQ 277
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 72.4 bits (177), Expect = 6e-18 Identities = 41/207 (19%), Positives = 83/207 (40%), Gaps = 12/207 (5%) Query: 6 QSGRPKDLEKRARILQAAKAIFLKSGYHGTSMNQIAQEAGVTKLTVYNHFQDKVNLFICA 65 + + + E R IL A +F + G TS+ +IA+ AGVT+ +Y HF+DK +LF Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS-E 61 Query: 66 ITETCEETLCTKQFDL--DTSADFYQTLFIVCSRALQIIYSPEALKLDHVLL---ELAAE 120 I E E + + + D L + L+ + E +L ++ Sbjct: 62 IWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVG 121 Query: 121 QNPLALQFFEASHTRMENQLAEFFQKAAQLGFIQAD-DPIYQTELLLTLLLGVRHHKVLL 179 + + Q +++ + + + + AD ++ + G+ + + Sbjct: 122 EMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF- 180 Query: 180 GITAAPNAQELEQIIRDAINLFLLKYR 206 AP + +L++ RD + + L Y Sbjct: 181 ----APQSFDLKKEARDYVAILLEMYL 203
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 30.3 bits (68), Expect = 0.009 Identities = 24/85 (28%), Positives = 35/85 (41%), Gaps = 10/85 (11%) Query: 330 RSAEIACVAVHPSYRKSNRGSQILQFLEEKAKEQGIRQLFVLTTR----TAHWFLEHGFH 385 A I +AV YRK G+ +L E AKE L + T H++ +H F Sbjct: 88 GYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFI 147 Query: 386 QVTVD-----DLPNAR-QALYNYQR 404 VD + P A A++ Y + Sbjct: 148 IGAVDTMLYSNFPTANEIAIFWYYK 172
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 87.0 bits (215), Expect = 1e-22 Identities = 54/203 (26%), Positives = 90/203 (44%), Gaps = 6/203 (2%) Query: 13 LKDRIILITGAGDGIGRAAALSYALHGATVVLHGRTLNKLEVIYDEIESLGAPQPAILPL 72 ++ +I ITGA GIG A A + A GA + KLE + A P Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKV-VSSLKAEARHAEAFPA 64 Query: 73 QLSSASDRDYDFLVDTLEKQFGRLDGILHNAGILGERVELAH-YPTEVWDDVMAVNLRAP 131 + ++ D + +E++ G +D +++ AG+L R L H E W+ +VN Sbjct: 65 DVRDSAA--IDEITARIEREMGPIDILVNVAGVL--RPGLIHSLSDEEWEATFSVNSTGV 120 Query: 132 FALTQALLPLLQKSENASVVFTSSGVGREARALWGAYSVSKIAIEAVSKIFAAENSYPNI 191 F ++++ + + S+V S R AY+ SK A +K E + NI Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNI 180 Query: 192 RFNCINPGATRTAMRAKAYPQED 214 R N ++PG+T T M+ + E+ Sbjct: 181 RCNIVSPGSTETDMQWSLWADEN 203
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 28.2 bits (63), Expect = 0.019 Identities = 14/49 (28%), Positives = 19/49 (38%), Gaps = 7/49 (14%) Query: 63 EPHMQTWLKQIPKDVRFVRTPAAMNKMWEQGARTYYTSEALGVRKRTHL 111 E + +P D R TPA+M R TS+ L R + L Sbjct: 162 ETELNEA---LPGDARDTTTPASMAATL----RKLLTSQRLSARSQRQL 203
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 55.8 bits (134), Expect = 8e-12 Identities = 17/62 (27%), Positives = 32/62 (51%), Gaps = 1/62 (1%) Query: 12 RKEKILSVAEKLLLENN-QEITLDELVAELDIAKGTLYKHFRSKNELLLELIIQNEKQIL 70 ++ IL VA +L + +L E+ + +G +Y HF+ K++L E+ +E I Sbjct: 12 TRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIG 71 Query: 71 EI 72 E+ Sbjct: 72 EL 73
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 53.1 bits (127), Expect = 8e-11 Identities = 23/72 (31%), Positives = 39/72 (54%), Gaps = 1/72 (1%) Query: 6 ERKQQSRQALLDAALHLSTSGRSFSSISLREVAREVGLVPTAFYRHFQDMDELGKELVDQ 65 + Q++RQ +LD AL L S + SS SL E+A+ G+ A Y HF+D +L E+ + Sbjct: 7 QEAQETRQHILDVALRL-FSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWEL 65 Query: 66 VALHLKSVLHQL 77 ++ + + Sbjct: 66 SESNIGELELEY 77
>PF07328#T-DNA border endonuclease VirD1 Length = 144 Score = 29.6 bits (66), Expect = 0.006 Identities = 10/45 (22%), Positives = 16/45 (35%) Query: 58 VNALISAYDNTVQVIWLKQEGERVAANEAFLKLAGSARSLLTVER 102 +N + A + T + ER KL+ L+ V R Sbjct: 85 INQIAKAANRTHDPAYHSFMAERKVLGLELSKLSAVLAPLMEVSR 129
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 31.0 bits (70), Expect = 0.014 Identities = 33/167 (19%), Positives = 59/167 (35%), Gaps = 41/167 (24%) Query: 218 IPPKVDFKHEGVERILKL---MLPALFGVSVTQINLLLNTIWASFMQDGSVSWLYSAERM 274 +P + + G+ +L PAL +S + L L ++ S+ SV M Sbjct: 850 LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV--------M 901 Query: 275 TELPLGLIGVAIGTVILPSLSARHAEQDQAKFRGMIDWAAKV--IVLVGLPASIALFMLS 332 +PLG++GV + + D V + +GL A A+ ++ Sbjct: 902 LVVPLGIVGVLLAATLFNQ---------------KNDVYFMVGLLTTIGLSAKNAILIVE 946 Query: 333 ----------TPIIQALFQRGEFDLRDTQMTALALQCMSAGVISFML 369 +++A LR MT+LA GV+ + Sbjct: 947 FAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLA---FILGVLPLAI 990
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 177 bits (449), Expect = 1e-57 Identities = 93/225 (41%), Positives = 131/225 (58%), Gaps = 3/225 (1%) Query: 11 IIATSTISLSV---FAAAPITNKSPAKEQFSYSYGYLMGRNNTDALTDLNLDIFYQGLQE 67 ++ + + L++ AA T+ + K++ SYS G +G+N + D+N D+ +G+Q+ Sbjct: 5 LVTAAIMGLAMSTAMAATDATSLTTDKDKLSYSIGADLGKNFKNQGIDINPDVLAKGMQD 64 Query: 68 GAQNKTARLTDEEMAKAINDYKKTLEAKQLVEFQKVGQQNAQAGAAFLADNAKKSGIITT 127 G LT+E+M ++ ++K L AK+ EF K ++N G AFL+ N K GI+ Sbjct: 65 GMSGAQLILTEEQMKDVLSKFQKDLMAKRSAEFNKKAEENKAKGDAFLSANKSKPGIVVL 124 Query: 128 KSGLQYQVLKEGTGKKPKAVSRVKVNYEGRLLDGTVFDSSIARNHPVEFQLSQVIAGWTE 187 SGLQY+++ GTG KP V V Y G L+DGTVFDS+ P FQ+SQVI GWTE Sbjct: 125 PSGLQYKIIDAGTGAKPGKSDTVTVEYTGTLIDGTVFDSTEKAGKPATFQVSQVIPGWTE 184 Query: 188 GLQTMKEGGKTRFFIPANLAYGEVGAGDTIGPNSTLIFDIELLQV 232 LQ M G F+PA+LAYG G IGPN TLIF I L+ V Sbjct: 185 ALQLMPAGSTWEVFVPADLAYGPRSVGGPIGPNETLIFKIHLISV 229
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 146 bits (370), Expect = 1e-45 Identities = 80/218 (36%), Positives = 121/218 (55%), Gaps = 9/218 (4%) Query: 29 TTEVGSKANKNASPIEKISYVLGYEVAQQTPP---ELDTKSFVKGIHDARNKQPSAYTQE 85 T + A + +K+SY +G ++ + +++ KG+ D + T+E Sbjct: 17 TAMAATDATSLTTDKDKLSYSIGADLGKNFKNQGIDINPDVLAKGMQDGMSGAQLILTEE 76 Query: 86 ELKAAVAAYEKELQQKMQQQ-DKPEQAAGAASESADVQFLAENKTKAGVKTTASGLQYII 144 ++K ++ ++K+L K + +K + A ++ FL+ NK+K G+ SGLQY I Sbjct: 77 QMKDVLSKFQKDLMAKRSAEFNKKAEENKAKGDA----FLSANKSKPGIVVLPSGLQYKI 132 Query: 145 TKEGTGKQPTAQSMVKVHYEGRLINGQVFDSSYKRGEPVEFPLNQVIPGWTEGLQLMKEG 204 GTG +P V V Y G LI+G VFDS+ K G+P F ++QVIPGWTE LQLM G Sbjct: 133 IDAGTGAKPGKSDTVTVEYTGTLIDGTVFDSTEKAGKPATFQVSQVIPGWTEALQLMPAG 192 Query: 205 GKATFFIPSNLAYGPQELPG-IPANSTLIFDVELISVK 241 F+P++LAYGP+ + G I N TLIF + LISVK Sbjct: 193 STWEVFVPADLAYGPRSVGGPIGPNETLIFKIHLISVK 230
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.7 bits (72), Expect = 0.010 Identities = 24/153 (15%), Positives = 54/153 (35%), Gaps = 23/153 (15%) Query: 245 QGQDKEHITKVLNAILATYSAQ------NIERRSAESA----------QTLKFLDEQLPD 288 ++ +T ++ +T+ Q N++++ AE + +L D Sbjct: 180 SEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDD 239 Query: 289 LKKQLDDAEREFNKFRQQYNT-VDVTKESELYLTQSITLETKKAELEQKQAEMVAKYTAE 347 L + +Q N V+ E +Y +Q +E++ +++ + + Sbjct: 240 FSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFK-- 297 Query: 348 HPAMREINGQLAAINKQIGELNSTLKQLPDVQR 380 EI +L IG L L + + Q+ Sbjct: 298 ----NEILDKLRQTTDNIGLLTLELAKNEERQQ 326
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 60.0 bits (145), Expect = 1e-12 Identities = 60/276 (21%), Positives = 103/276 (37%), Gaps = 37/276 (13%) Query: 19 LSVVVFAFLVLWLCWKLASLFWWVIAP---PQMMQFDRVELGSQQPQIPNIST-FSLFNE 74 + ++F L+L C +LA +FW + P P QQP N T F + E Sbjct: 14 IRRILFYLLMLLFCQQLAMIFWRIGLPDNAPVSSVQITPAQARQQPVTLNDFTLFGVSPE 73 Query: 75 P----------SANAAQENVNLELQGVMLGYPNRFSSAVIKLDNIADRYRVGETIGSTSY 124 +N +NL L GVM G + S A+I DN V E + + Sbjct: 74 KNKAGALDASQMSNLPPSTLNLSLTGVMAGDDDSRSIAIISKDNEQFSRGVNEEVPGYNA 133 Query: 125 QLAEVYWDHVILRQGNGSTRELQFKGLPNGLYQPMTPDASQPTATAPQSSAPVNTTQEAL 184 ++ + D V+L+ G Y+ + + + + + A VN E L Sbjct: 134 KIVSIRPDRVVLQY--------------QGRYEVLGLYSQEDSGSDGVPGAQVN---EQL 176 Query: 185 GQ-AIQQMQGNREQYLRDMGVS-GNSGEGFEVTERTPTALRNKLGLRPGDRIVSLNGQTV 242 Q A M Y+ + N +G+ + + ++GL+ D V+LNG + Sbjct: 177 QQRASTTMS----DYVSFSPIMNDNKLQGYRLNPGPKSDSFYRVGLQDNDMAVALNGLDL 232 Query: 243 GQGQTDVQLLEQARRAGQVKIEIKRGDQVMTIQQNF 278 + + +E+ + ++R Q I F Sbjct: 233 RDAEQAKKAMERMADVHNFTLTVERDGQRQDIYMEF 268
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 425 bits (1095), Expect = e-142 Identities = 223/692 (32%), Positives = 338/692 (48%), Gaps = 73/692 (10%) Query: 12 ALLAAAPLIATVSSSVYAQTWKINLRDADLTAFINEVADITGKNFAVDPRVRGNVTVISN 71 LL A L+ +++ + + + + D+ FIN V+ K +DP VRG +TV S Sbjct: 13 TLLIFAALLFRPAAA---EEFSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRSY 69 Query: 72 KPLNKNEVYDLFLGVLNVNGVVAIPSGN-TIKLVPDSNVKNSGIPYDSRNK-LRGDQIVT 129 LN+ + Y FL VL+V G I N +K+V + K + +P S GD++VT Sbjct: 70 DMLNEEQYYQFFLSVLDVYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIGDEVVT 129 Query: 130 RVIWLENTNPNDLIPALRPLMPQFAHMAAI--AGTNALIVSDRAANIYQLENIIRNLDGT 187 RV+ L N DL P LR L + + +N L+++ RAA I +L I+ +D Sbjct: 130 RVVPLTNVAARDLAPLLRQLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDNA 189 Query: 188 GQNDIEAINLQSSQAEEIITQLEAMSATGASKDFNGARI-RIIADNRTNRILVKGDPETR 246 G + + L + A +++ + ++ + G+ + ++AD RTN +LV G+P +R Sbjct: 190 GDRSVVTVPLSWASAADVVKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSGEPNSR 249 Query: 247 KRIRHMIEMLDVPSADRLGGLKVFRLKYASAKNLSEILQGLVTGQAVSSSNSNNSSSNSS 306 +RI MI+ LD A G KV LKYA A +L E+L G+ Sbjct: 250 QRIIAMIKQLDRQQA-TQGNTKVIYLKYAKASDLVEVLTGI------------------- 289 Query: 307 NPINNLMGNNQNSSSNTSGSNGSSISTPSINLNGNSNNNNQNSISSFSQNGVSIIADNAQ 366 + S + + + I A Sbjct: 290 ---------SSTMQSEKQAAKPVAAL----------------------DKNIIIKAHGQT 318 Query: 367 NSLVVKADPQLMREIESAIQQLDVRRQQVLIEAAIIEVSGKDADQLGVQWALGDINSGIG 426 N+L+V A P +M ++E I QLD+RR QVL+EA I EV D LG+QWA N G Sbjct: 319 NALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLGIQWA----NKNAG 374 Query: 427 LINFTNAGSSLASLAAGYLTGGASG-LGSAIGAGSSIALGKYKEGADGSRQLYGALIQAL 485 + FTN+G +++ AG G + S++ + S G A + + L+ AL Sbjct: 375 MTQFTNSGLPISTAIAGANQYNKDGTVSSSLASALSSFNG---IAAGFYQGNWAMLLTAL 431 Query: 486 KENTASNLLSTPSIVTMDNEEAYIVVGQNVPFVTGSVTTNSTGINPYTTVERKDVGVTLK 545 +T +++L+TPSIVT+DN EA VGQ VP +TGS TT+ N + TVERK VG+ LK Sbjct: 432 SSSTKNDILATPSIVTLDNMEATFNVGQEVPVLTGSQTTSGD--NIFNTVERKTVGIKLK 489 Query: 546 VIPHIGENGTVRLEIEQEVSNVQASKGQAA---DLITNKRAIKTAVLAEHGQTVVLGGLV 602 V P I E +V LEIEQEVS+V + + N R + AVL G+TVV+GGL+ Sbjct: 490 VKPQINEGDSVLLEIEQEVSSVADAASSTSSDLGATFNTRTVNNAVLVGSGETVVVGGLL 549 Query: 603 SDDVEFNRQGIPGLSSIPYLGRLFRSDTRSNVKRNLLVFIHPTIVGDANDVRRLSQQRYS 662 V +P L IP +G LFRS ++ KRNL++FI PT++ D ++ R+ S +Y+ Sbjct: 550 DKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRNLMLFIRPTVIRDRDEYRQASSGQYT 609 Query: 663 QLYSLQL-AMDKNGNFAKLPEQVDDVYNQKMT 693 Q K N A L + + ++Y ++ T Sbjct: 610 AFNDAQSKQRGKENNDAMLNQDLLEIYPRQDT 641
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 77.2 bits (190), Expect = 2e-17 Identities = 50/149 (33%), Positives = 77/149 (51%), Gaps = 5/149 (3%) Query: 13 VNVGTIGHVDHGKTTLTAAI--ATICAKTYGGEAKDYSQIDSAPEEKARGITINTSHVEY 70 +N+G + HVD GKTTLT ++ + G K ++ D+ E+ RGITI T + Sbjct: 4 INIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSF 63 Query: 71 DSPIRHYAHVDCPGHADYVKNMITGAAQMDGAILVCAATDGPMPQTREHILLSRQVGVPY 130 +D PGH D++ + + +DGAIL+ +A DG QTR R++G+P Sbjct: 64 QWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIP- 122 Query: 131 IIVFLNKCDLVDDEELLELVEMEVRELLS 159 I F+NK D + L V +++E LS Sbjct: 123 TIFFINKIDQNGID--LSTVYQDIKEKLS 149
>SECETRNLCASE#Bacterial translocase SecE signature. Length = 127 Score = 76.8 bits (189), Expect = 4e-21 Identities = 46/126 (36%), Positives = 66/126 (52%), Gaps = 5/126 (3%) Query: 21 SAEVVRSGSPLDIVLWVIAIALLLLATMVNQHLPAYWAPANNVWVRVGAIFACIVVALGL 80 + E SG L+ + WV+ +ALLL+A + N P +R A+ I A G+ Sbjct: 4 NTEAQGSGRGLEAMKWVVVVALLLVAIVGNYLYRDIMLP-----LRALAVVILIAAAGGV 58 Query: 81 LYATHQGKGFVRLLKDARVELRRVTWPTKQETVTTSWQVLLVVVVASLVLWCFDYGLGWL 140 T +GK V ++AR E+R+V WPT+QET+ T+ V V V SL+LW D L L Sbjct: 59 ALLTTKGKATVAFAREARTEVRKVIWPTRQETLHTTLIVAAVTAVMSLILWGLDGILVRL 118 Query: 141 IKLIIG 146 + I G Sbjct: 119 VSFITG 124
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 33.1 bits (75), Expect = 0.003 Identities = 42/239 (17%), Positives = 90/239 (37%), Gaps = 5/239 (2%) Query: 155 AEANDVREAYSTWQRTIRLHQAALDAQATRLQRIGTLEHQIEELEEVIQTDYKEIEQEFD 214 A A + + + A T LE + ELE+ ++ + Sbjct: 222 ALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSA 281 Query: 215 RLSHHEHIMQDCSYSLNVLDEAEQNITQEMSSIIRRLESHAGRSEQLSEIYNSLLNAQSE 274 ++ E L+ Q + S+ R L++ +QL + L Sbjct: 282 KIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKI 341 Query: 275 IDDATANLRQFIDRQSFDPERMEELNSKLEVFHRLARKYRT----QPETLKEEYEAWQSE 330 + + +LR+ +D +++E + KLE ++++ R + +E + + Sbjct: 342 SEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKA 401 Query: 331 LEQLH-QLEDPETLAEQVEKSHEEFLEKAQHLDNIRRESAAPLAKQLTEQVKPLALPEA 388 LE+ + +L E L +++E+S + ++ L A L ++L +Q + LA A Sbjct: 402 LEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEKLAKQAEELAKLRA 460
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 79.5 bits (196), Expect = 3e-17 Identities = 70/348 (20%), Positives = 119/348 (34%), Gaps = 91/348 (26%) Query: 406 IMGHVDHGKTSLLDRIRRSKVAAGEAG------------------GITQHIGAYHVETDK 447 ++ HVD GKT+L + + + A E G GIT G + + Sbjct: 8 VLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWEN 67 Query: 448 GIITFLDTPGHAAFTSMRARGAKATDIVVLVVAADDGVMPQTAEAIDHARAAGTPIIVAI 507 + +DTPGH F + R D +L+++A DGV QT R G P I I Sbjct: 68 TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFI 127 Query: 508 NKMDKESADPDRVLNEL---------------------TTKQIVPEEW------------ 534 NK+D+ D V ++ T E+W Sbjct: 128 NKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGNDDLLE 187 Query: 535 -----------------------GGDVPIAKVSAHSGQGIDELLDLILIQSELMELKASA 571 P+ SA + GID L+++I ++ Sbjct: 188 KYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVIT--NKFYSSTHRG 245 Query: 572 EGAAQGVVIEARVDKGRGAVTSILVQNGTLNIGDLVL-AGSSYGRVRAM-SDENGKPIKS 629 + G V + + R + I + +G L++ D V + ++ M + NG+ K Sbjct: 246 QSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKIKITEMYTSINGELCKI 305 Query: 630 AGPSIPVEILGLPDAPMAGDEVLVVNDEKKAREVADARADRERQKRID 677 D +G+ V++ N+ K V +++RI+ Sbjct: 306 -------------DKAYSGEIVILQNEFLKLNSVLGDTKLLPQRERIE 340
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 48.3 bits (115), Expect = 3e-08 Identities = 60/395 (15%), Positives = 121/395 (30%), Gaps = 29/395 (7%) Query: 34 ALLFAYFAMVVDGIDIMLLSYSLTSLKAEFGLSTFQAGALGSA----SLAGMGIGGILGG 89 L+ + +D + I L+ L L + S G +L +LG Sbjct: 6 PLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGA 65 Query: 90 WACDKFGRVRTIANSVTFFSVATCLLGFTQSFEQFMALRFIGALGIGALYMACNTLMAEY 149 + D+FGR + S+ +V ++ R + + GA +A+ Sbjct: 66 LS-DRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGI-TGATGAVAGAYIADI 123 Query: 150 VPTTYRTTVLGTLQTGQTVGYIAATLLAGAIIPDHGWRVLFFLTVVPAFVNIFLQRFVPE 209 R G + G +A +L G + F + + +PE Sbjct: 124 TDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPE 183 Query: 210 PKSWQLTKIESLQGNSQPKEMVVAEKPKSGSIYKQIFNNFKHRKMFLLWMTTAFFLQ-FG 268 +G +P A P + + + + M F +Q G Sbjct: 184 SH----------KGERRPLRR-EALNPLASFRWARGM------TVVAALMAVFFIMQLVG 226 Query: 269 YYGINNWMPSYLETEVHMNFKNLT-SYMVGSYTAMILGKILAGYLADKFNRRAVFVFGTI 327 W+ + E H + + S + ++ G +A + R + G I Sbjct: 227 QVPAALWV-IFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMI 285 Query: 328 ASAVFLPIIIFFNTPDNILYLLITFGFLYGIPYGVNATYMAESFSTDVRGTAIGGAYNIG 387 A ++ F +++ GI ++ + +G G + Sbjct: 286 ADGTGYILLAFATRGWMAFPIMVLLAS-GGIGMPALQAMLSRQVDEERQGQLQGSLAALT 344 Query: 388 RVGAAIAPATIGFL--ASGGTFTMAFIVMGAAYFV 420 + + + P + AS T+ + GAA ++ Sbjct: 345 SLTSIVGPLLFTAIYAASITTWNGWAWIAGAALYL 379
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.4 bits (66), Expect = 0.026 Identities = 10/19 (52%), Positives = 12/19 (63%) Query: 293 RDELIPLLSEHFLQKTAKE 311 R E IP L HF+Q+ KE Sbjct: 313 RAEDIPDLVRHFVQQAEKE 331
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 61.6 bits (149), Expect = 4e-14 Identities = 29/176 (16%), Positives = 59/176 (33%), Gaps = 18/176 (10%) Query: 7 KILDTAEKLFNENSFVGVGVDLIRDESGCSKTTMYTYYKNKNQLVKSVLVARDERFKQSL 66 ILD A +LF++ + I +G ++ +Y ++K+K+ L + + + Sbjct: 15 HILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELE 74 Query: 67 LGYVGDATG------LEAINKILDWHTNWFRQDFFKGCLFVR--AVAESNQDDQDIISIS 118 L Y G E + +L+ R+ +F + V E Q ++ Sbjct: 75 LEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRNLC 134 Query: 119 KAHKQWIKVLIAENCNIPNGE--------ALSELIYTVIEGLISRFLVDGFDETLA 166 I+ + I + ++ I GL+ +L L Sbjct: 135 LESYDRIEQTLKH--CIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLK 188
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 29.4 bits (66), Expect = 0.023 Identities = 14/46 (30%), Positives = 23/46 (50%), Gaps = 3/46 (6%) Query: 305 DRGFIFLLLIVSASGLALMAFRNTPYMALLLIFHLATVMTFFITMP 350 +R + L +I +G L+AF +MA ++ LA + I MP Sbjct: 276 ERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLA---SGGIGMP 318