PredictBias

		>BONTOXILYSIN#Bontoxilysin signature.

		          Length = 1196

		

		 Score = 27.9 bits (62), Expect = 0.034

		 Identities = 8/35 (22%), Positives = 15/35 (42%), Gaps = 3/35 (8%)

		

		Query: 127 IAKLSKEFSPIYSKRLNNK-KQYRAYRHAYMVLEL 160

		           +    + F+ I   R +N  K +  YR  Y  ++ 

		Sbjct: 336 LNYFCQSFNSIIPDRFSNALKHF--YRKQYYTMDY 368

		

		

		>FLGFLGJ#Flagellar protein FlgJ signature.

		          Length = 313

		

		 Score = 28.9 bits (64), Expect = 0.043

		 Identities = 21/127 (16%), Positives = 40/127 (31%), Gaps = 19/127 (14%)

		

		Query: 128 AHNMGGVK----WNKRSDFTQTISLYGNSSVAESGPGTNVGDGTGGEYAFFSTFDSGIVG 183

		           ++N+ GVK    W        T       +                ++  +S++   +  

		Sbjct: 197 SYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKA-----------KFRVYSSYLEALSD 245

		

		Query: 184 KAEFMKNQTLYKGAINNTDGISTLSAIADGGWATDPSYKTKLHDLYNSLGSKFKWLDEKA 243

		               +     Y              A+ D G+ATDP Y  KL     ++  + K + +K 

		Sbjct: 246 YVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKL----TNMIQQMKSISDKV 301

		

		Query: 244 ISQYGSS 250

		              Y  +

		Sbjct: 302 SKTYSMN 308

		

		

		>GPOSANCHOR#Gram-positive coccus surface protein anchor signature.

		          Length = 539

		

		 Score = 47.0 bits (111), Expect = 7e-08

		 Identities = 26/109 (23%), Positives = 37/109 (33%), Gaps = 18/109 (16%)

		

		Query: 226 KQPDPKPAVPDPSDQQPAPKAPSKPKASQKPADQVAKGNGAEPNAADPTISVQGSAENSN 285

		           K+   K A      ++ A     K   SQ P  +               +  +G A  + 

		Sbjct: 445 KEKLAKQA------EELAKLRAGKASDSQTPDAKPGN----------KAVPGKGQAPQAG 488

		

		Query: 286 NKAKENKPVATPAAPVLPATG--TNQSFLALIGTVMLSVLAFVGFKRKK 332

		            K  +NK         LP+TG   N  F A   TVM +       KRK+

		Sbjct: 489 TKPNQNKAPMKETKRQLPSTGETANPFFTAAALTVMATAGVAAVVKRKE 537

		

		

		

		 Score = 34.3 bits (78), Expect = 7e-04

		 Identities = 18/78 (23%), Positives = 30/78 (38%), Gaps = 7/78 (8%)

		

		Query: 221 RPGQPKQPDPKPAVPDPSDQQPAPKAPSKPKASQKPADQVAK-----GNGAEP--NAADP 273

		           +    + PD KP       +  AP+A +KP  ++ P  +  +     G  A P   AA  

		Sbjct: 462 KASDSQTPDAKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGETANPFFTAAAL 521

		

		Query: 274 TISVQGSAENSNNKAKEN 291

		           T+           + +EN

		Sbjct: 522 TVMATAGVAAVVKRKEEN 539

		

		

		>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature.

		          Length = 1291

		

		 Score = 29.2 bits (65), Expect = 0.020

		 Identities = 18/76 (23%), Positives = 31/76 (40%), Gaps = 8/76 (10%)

		

		Query: 170 WDFQNVETVYYVSNGNFLVLVEDLDQEVKEYFQEKVRDDLTMMHFENKKTDQKIQFQSGS 229

		           WD+ N    Y+V +G +  L  D+   V  Y    + +      F     D  +  Q  +

		Sbjct: 113 WDWGNAARHYWVKDGQWNKLEVDMQNAVGTYNLSGLIN------FTGGDLD--VNMQKAT 164

		

		Query: 230 LKLNAQNIDKFHNFDD 245

		           L+L   N + F ++ D

		Sbjct: 165 LRLGQFNGNSFTSYKD 180

		

		

		>BCTERIALGSPF#Bacterial general secretion pathway protein F

		           signature.

		          Length = 408

		

		 Score = 86.0 bits (213), Expect = 7e-21

		 Identities = 59/295 (20%), Positives = 124/295 (42%), Gaps = 16/295 (5%)

		

		Query: 50  VTEMRAGLSAGQSFSEIVSRLG--FSDSVVTQLSLSELHGNLTLSLGKIEAYLENLSKVK 107

		           +  +R+ +  G S ++ +      F       ++  E  G+L   L ++  Y E   +++

		Sbjct: 107 MAAVRSKVMEGHSLADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMR 166

		

		Query: 108 KKLIEVGTYPLMLLGFLVLIMLGLRNYLLPQLDSQ--------NLATQLINHLPQIFL-W 158

		            ++ +   YP +L    + ++  L + ++P++  Q         L+T+++  +      +

		Sbjct: 167 SRIQQAMIYPCVLTVVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTF 226

		

		Query: 159 SSLVLAILVSLAV----FYYRKSSKIRFFSKLAALPFFGRLVQAYLTAYYAREWGNMIGQ 214

		              +L  L++  +       ++  ++ F  +L  LP  GR+ +   TA YAR    +   

		Sbjct: 227 GPWMLLALLAGFMAFRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNAS 286

		

		Query: 215 GLELSQIFAIMQEQPS-QLFQEIGEDMAAALQGGQGYADKVASYPFFKKELSLMIEYGEV 273

		            + L Q   I  +  S    +        A++ G      +     F   +  MI  GE 

		Sbjct: 287 AVPLLQAMRISGDVMSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGER 346

		

		Query: 274 KSKLGSELEVYAEKTWEEFFLRINRAMNFIQPLVFIFVALVIVLLYAAMLLPIYQ 328

		             +L S LE  A+    EF  ++  A+   +PL+ + +A V++ +  A+L PI Q

		Sbjct: 347 SGELDSMLERAADNQDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQ 401

		

		

		

		 Score = 36.3 bits (84), Expect = 1e-04

		 Identities = 31/140 (22%), Positives = 61/140 (43%), Gaps = 12/140 (8%)

		

		Query: 202 AYYAREWGNMIGQGLELSQIFAIMQEQPSQLFQEIGEDMAA---ALQGGQGYADKVASYP 258

		           A   R+   ++   + L +    + +Q  +    + + MAA    +  G   AD +  +P

		Sbjct: 71  ALLTRQLATLVAASMPLEEALDAVAKQSEK--PHLSQLMAAVRSKVMEGHSLADAMKCFP 128

		

		Query: 259 -FFKKELSLMIEYGEVKSKLGSELE---VYAEKTWEEFFLRINRAMNFIQPLVFIFVALV 314

		             F++    M+  GE    L + L     Y E+  ++   RI +AM  I P V   VA+ 

		Sbjct: 129 GSFERLYCAMVAAGETSGHLDAVLNRLADYTEQR-QQMRSRIQQAM--IYPCVLTVVAIA 185

		

		Query: 315 IVLLYAAMLLPIYQNMEVHL 334

		           +V +  ++++P      +H+

		Sbjct: 186 VVSILLSVVVPKVVEQFIHM 205

		

		

		>BCTERIALGSPG#Bacterial general secretion pathway protein G

		          signature.

		          Length = 145

		

		 Score = 46.4 bits (110), Expect = 8e-10

		 Identities = 25/82 (30%), Positives = 44/82 (53%), Gaps = 7/82 (8%)

		

		Query: 1  MKKFNTLKVQAFTLVEMLIVLLVISVLLLLFVPNLTKQKDAVSDTGTAAVVKVVESQAEL 60

		          M+  +  K + FTL+E+++V+++I VL  L VPNL   K+        + +  +E+  ++

		Sbjct: 1  MRATD--KQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDM 58

		

		Query: 61 YELKN----TNEKASLSKLVSA 78

		          Y+L N    T  +  L  LV A

		Sbjct: 59 YKLDNHHYPTTNQG-LESLVEA 79

		

		

		>ACETATEKNASE#Acetate kinase family signature.

		          Length = 400

		

		 Score =  518 bits (1336), Expect = 0.0

		 Identities = 206/395 (52%), Positives = 283/395 (71%), Gaps = 6/395 (1%)

		

		Query: 3   KTISINAGSSSLKWQLYLMPEEKVLAKGLLERIGLKDSISTVKFDGRSEKQVLDIADHTQ 62

		           K + IN GSSSLK+QL    +  VLAKGL ERIG+ DS+ T   +G   K   D+ DH  

		Sbjct: 2   KILVINCGSSSLKYQLIESKDGNVLAKGLAERIGINDSLLTHNANGEKIKIKKDMKDHKD 61

		

		Query: 63  AVKILLDDL--KRFNIIESYDEITGVGHRVVAGGEHFKDSALVDEEVIQKVEELSLLAPL 120

		           A+K++LD L    + +I+   EI  VGHRVV GGE+F  S L+ ++V++ + +   LAPL

		Sbjct: 62  AIKLVLDALVNSDYGVIKDMSEIDAVGHRVVHGGEYFTSSVLITDDVLKAITDCIELAPL 121

		

		Query: 121 HNPANAAGIRAFREILPDITSVVVFDTSFHTTMPEKAYRYPIPTKYYTENKVRKYGAHGT 180

		           HNPAN  GI+A  +I+PD+  V VFDT+FH TMP+ AY YPIP +YYT+ K+RKYG HGT

		Sbjct: 122 HNPANIEGIKACTQIMPDVPMVAVFDTAFHQTMPDYAYLYPIPYEYYTKYKIRKYGFHGT 181

		

		Query: 181 SHEYVAKEAAKILGRPIEELKLITCHIGNGASITAVDKGVSVDTSMGFTPLGGVMMGTRT 240

		           SH+YV++ AA+IL +PIE LK+ITCH+GNG+SI AV  G S+DTSMGFTPL G+ MGTR+

		Sbjct: 182 SHKYVSQRAAEILNKPIESLKIITCHLGNGSSIAAVKNGKSIDTSMGFTPLEGLAMGTRS 241

		

		Query: 241 GDIDPAIIPYLMQYTDDFNTPEDISRVLNRESGLLGVSEKSSDMRDIHE-AMRAGDAKAQ 299

		           G IDP+II YLM+  +   + E++  +LN++SG+ G+S  SSD RD+ + A + GD +AQ

		Sbjct: 242 GSIDPSIISYLMEKEN--ISAEEVVNILNKKSGVYGISGISSDFRDLEDAAFKNGDKRAQ 299

		

		Query: 300 LANDIFVDRIQKYIGQYLAVLNGADAIIFTAGIGENSVTIRELVINGISWFGCNVDPEKN 359

		           LA ++F  R++K IG Y A + G D I+FTAGIGEN   IRE +++G+ + G  +D EKN

		Sbjct: 300 LALNVFAYRVKKTIGSYAAAMGGVDVIVFTAGIGENGPEIREFILDGLEFLGFKLDKEKN 359

		

		Query: 360 -VRGAEGVISSPDAKVKVLVIPTDEELVIARDVER 393

		            VRG E +IS+ D+KV V+V+PT+EE +IA+D E+

		Sbjct: 360 KVRGEEAIISTADSKVNVMVVPTNEEYMIAKDTEK 394

		

		

		>ACRIFLAVINRP#Acriflavin resistance protein family signature.

		          Length = 1034

		

		 Score = 28.3 bits (63), Expect = 0.038

		 Identities = 17/65 (26%), Positives = 33/65 (50%), Gaps = 3/65 (4%)

		

		Query: 126 GLDFSWSLLGKFLYYSFFGLLSNLFLAFLTAG--LALLFQSWVVPVSVLFPL-LIGLSRL 182

		           G+ + W+ +      S     + + ++F+     LA L++SW +PVSV+  + L  +  L

		Sbjct: 853 GIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVL 912

		

		Query: 183 LATFI 187

		           LA  +

		Sbjct: 913 LAATL 917

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 82.2 bits (203), Expect = 3e-20

		 Identities = 35/133 (26%), Positives = 58/133 (43%), Gaps = 2/133 (1%)

		

		Query: 4   MRQYRILVVDDDRSILKLVKNVLELDAYDVTTLDRIEE-LELTNFVGYDLILLDVMMEPV 62

		           M    ILV DDD +I  ++   L    YDV                  DL++ DV+M   

		Sbjct: 1   MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60

		

		Query: 63  NGFELCSYIR-PHISCPIIFLTAKELEADKVEGLFRGADDYIVKPFGTKELLARVRAHLR 121

		           N F+L   I+      P++ ++A+      ++   +GA DY+ KPF   EL+  +   L 

		Sbjct: 61  NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120

		

		Query: 122 REERREERYSEIA 134

		             +RR  +  + +

		Sbjct: 121 EPKRRPSKLEDDS 133

		

		

		>PF05272#Virulence-associated E family protein

		          Length = 892

		

		 Score = 31.6 bits (71), Expect = 0.007

		 Identities = 13/56 (23%), Positives = 25/56 (44%), Gaps = 7/56 (12%)

		

		Query: 42  MILYGPPGIGKTSIASAIAGTTKF--AFRTFNATVDSKKRLQ-----EVAEEAKFS 90

		           ++L G  GIGK+++ + + G   F           DS +++      E++E   F 

		Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIAGIVAYELSEMTAFR 654

		

		

		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

		           signature.

		          Length = 261

		

		 Score =  101 bits (252), Expect = 1e-27

		 Identities = 66/235 (28%), Positives = 106/235 (45%), Gaps = 16/235 (6%)

		

		Query: 7   KVILVTGASSGIGYQTAEQLAKEGHIVYGA------ARRVDAMKPLEAFGVTPVSLDITD 60

		           K+  +TGA+ GIG   A  LA +G  +           +V +    EA        D+ D

		Sbjct: 9   KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68

		

		Query: 61  EASIKEALNLIIKKENRIDVLVNNAGYGSYGAVEDVRIEEAKMQFEVNIFGLARLTQLVL 120

		            A+I E    I ++   ID+LVN AG    G +  +  EE +  F VN  G+   ++ V 

		Sbjct: 69  SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128

		

		Query: 121 PYMRKQKSGRIINVGSMGGRLTSYFGAWYHATKYALEAFSDGLRMEVADFGIDVSIIEPG 180

		            YM  ++SG I+ VGS    +     A Y ++K A   F+  L +E+A++ I  +I+ PG

		Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188

		

		Query: 181 GIKTD--WGFIAADKLAESAKGGAYEAAATKAAEGMRKQYSGNMMSNPKVISNAI 233

		             +TD  W   A +  AE    G        + E  +       ++ P  I++A+

		Sbjct: 189 STETDMQWSLWADENGAEQVIKG--------SLETFKTGIPLKKLAKPSDIADAV 235

		

		

		>NUCEPIMERASE#Nucleotide sugar epimerase signature.

		          Length = 334

		

		 Score = 55.2 bits (133), Expect = 1e-10

		 Identities = 62/320 (19%), Positives = 112/320 (35%), Gaps = 52/320 (16%)

		

		Query: 18  FVTGATGLLGNNLVRALLKENIQVTAL--------VRSEEKARKQFADLPIQIVKGDILE 69

		            VTGA G +G ++ + LL+   QV  +        V  ++   +  A    Q  K D+ +

		Sbjct: 4   LVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDLAD 63

		

		Query: 70  PESYRDYLA--GCDSLFHTAAFFRDNYKGGKHWQELYDTNIIGTNNLLEAAYEAGIRQFV 127

		            E   D  A    + +F +       Y          D+N+ G  N+LE      I+  +

		Sbjct: 64  REGMTDLFASGHFERVFISPHRLAVRYSLENPHA-YADSNLTGFLNILEGCRHNKIQHLL 122

		

		Query: 128 HTSSCVVLEGEANQLIDESMSRSKDTPFDYYRSKILSEEAVRDFLDKHSDVFGCFILPSV 187

		           + SS  V     N+ +  S   S D P   Y +   + E +      +S ++G   LP+ 

		Sbjct: 123 YASSSSVY--GLNRKMPFSTDDSVDHPVSLYAATKKANELM---AHTYSHLYG---LPAT 174

		

		Query: 188 ML------GPR---DLGPTSSGQMIIN-----------------FVEQKLPGILKASYNM 221

		            L      GP    D+      + ++                  +++     I++    +

		Sbjct: 175 GLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVI 234

		

		Query: 222 VDARDVADIHLRAMKYGRSKERYLAVG--RQVTMTELYQILEKITGVPAPKRKISPLF-- 277

		             A     +         +  R   +G    V + +  Q LE   G+ A K+ + PL   

		Sbjct: 235 PHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEA-KKNMLPLQPG 293

		

		Query: 278 --VKIYAQASELYHRLTKKP 295

		             ++  A    LY  +   P

		Sbjct: 294 DVLETSADTKALYEVIGFTP 313

		

		

		>SACTRNSFRASE#Streptothricin acetyltransferase signature.

		          Length = 173

		

		 Score = 29.9 bits (67), Expect = 0.002

		 Identities = 20/89 (22%), Positives = 35/89 (39%), Gaps = 7/89 (7%)

		

		Query: 42  EVLRSDVNSCALAEDENRLVAFL-VWQETDFEAEVLQIAVLPSYQGQKIATAL------F 94

		             +  +  +  L   EN  +  + +    +  A +  IAV   Y+ + + TAL      +

		Sbjct: 58  SYVEEEGKAAFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEW 117

		

		Query: 95  AFLPADKEIFLEVRESNKPALLFYKKEKF 123

		           A       + LE ++ N  A  FY K  F

		Sbjct: 118 AKENHFCGLMLETQDINISACHFYAKHHF 146

		

		

		>PF07520#Virulence protein SrfB

		          Length = 1041

		

		 Score = 28.8 bits (64), Expect = 0.039

		 Identities = 18/82 (21%), Positives = 30/82 (36%), Gaps = 10/82 (12%)

		

		Query: 85  QHYYPAFHQEDVTLRQLLTHTSGL-DPF--IPNREQLTAPKLKEALNHLTVLEDKTFRYT 141

		            H+ P  +     +R  + H +   D    +     L   K K+       +  +  R +

		Sbjct: 403 NHHDP--NNLPRPVRAAMRHLNEAGDVLAQVKTEIGLNLRKPKKTTPLTPAIRPRFSRSS 460

		

		Query: 142 DVNFLLLGFMLEEIFGQALDQI 163

		                L GFML E+   A+ QI

		Sbjct: 461 -----LFGFMLAEVIAHAMVQI 477

		

		

		>PF06580#Sensor histidine kinase

		          Length = 349

		

		 Score = 30.2 bits (68), Expect = 0.008

		 Identities = 23/129 (17%), Positives = 45/129 (34%), Gaps = 12/129 (9%)

		

		Query: 78  FIFSHAKGWWIYMLVFCLVRVLTLFIANPVLPPLNAILMFPLGWTFVTFAGGGNEEIGWR 137

		           + +    GW +Y L             +P L   + I    +    +         I  +

		Sbjct: 12  YWYCQGIGWGVYTLTGF---GFASLYGSPKL--HSMIFNIAISLMGLVLTHAYRSFIKRQ 66

		

		Query: 138 GLLQPALEKK-FCFPLATVITALVWVAWHLPLWLIP---GTSQSQVSLPFYLSFG---IL 190

		           G L+  + +       A V+  +VW   +  +W +     T     +LP  LS     ++

		Sbjct: 67  GWLKLNMGQIILRVLPACVVIGMVWFVANTSIWRLLAFINTKPVAFTLPLALSIIFNVVV 126

		

		Query: 191 LCFCQAVLY 199

		           + F  ++LY

		Sbjct: 127 VTFMWSLLY 135

		

		

		>HTHTETR#TetR bacterial regulatory protein HTH signature.

		          Length = 215

		

		 Score = 75.8 bits (186), Expect = 4e-19

		 Identities = 44/190 (23%), Positives = 81/190 (42%), Gaps = 10/190 (5%)

		

		Query: 1   MAQR-KDKSQAMREKILNTATQLFIQKGSEKTSMQDIAQTAGISKGAIYHHFKSKDEIVL 59

		           MA++ K ++Q  R+ IL+ A +LF Q+G   TS+ +IA+ AG+++GAIY HFK K ++  

		Sbjct: 1   MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60

		

		Query: 60  AVMRSRQELMEEEMKQWLKATENLTGREQLQTILKSNLES-------QTARATDGILGEY 112

		            +    +  +  E++   +A         L+ IL   LES       +          E+

		Sbjct: 61  EIWELSESNI-GELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEF 119

		

		Query: 113 EKDAGFILTMMRDNLWISAPLVSDIIKKGMADGSLQTQY-PDQAAEVFLLLVNFWMHGTV 171

		             +   +    R+    S   +   +K  +    L       +AA +    ++  M   +

		Sbjct: 120 VGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWL 179

		

		Query: 172 FESDPEKLPE 181

		           F      L +

		Sbjct: 180 FAPQSFDLKK 189

		

		

		>UREASE#Urea amidohydrolase (urease) protein signature.

		          Length = 570

		

		 Score = 51.7 bits (124), Expect = 3e-09

		 Identities = 23/53 (43%), Positives = 33/53 (62%), Gaps = 6/53 (11%)

		

		Query: 39  IAVKDGKILAVG-SGEPDAS-----LVGPDTKIQSYEGKIATPGLIDCHTHLV 85

		           I +KDG+I A+G +G PD       +VGP T++ + EGKI T G +D H H +

		Sbjct: 88  IGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIVTAGGMDSHIHFI 140

		

		

		>HTHTETR#TetR bacterial regulatory protein HTH signature.

		          Length = 215

		

		 Score = 75.0 bits (184), Expect = 6e-19

		 Identities = 33/162 (20%), Positives = 62/162 (38%), Gaps = 3/162 (1%)

		

		Query: 8   EVRRAEIMSAALQLFAQKGYLKTRTQDIIDKLGISRGLLYYHFKDKEDILYCLIEKNSEP 67

		           +  R  I+  AL+LF+Q+G   T   +I    G++RG +Y+HFKDK D+   + E +   

		Sbjct: 10  QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESN 69

		

		Query: 68  LLRKLETISYQPNVGAKEKIRTFIEATL---IPEESRTQENQVLQETVNLETNRYVLDRF 124

		           +         +        +R  +   L   + EE R    +++           V+ + 

		Sbjct: 70  IGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQA 129

		

		Query: 125 YHRLCERMIIFFTHILEEGQKSGDFHLKYPHEMASFLMTAYV 166

		              LC          L+   ++           A+ +M  Y+

		Sbjct: 130 QRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYI 171

		

		

		>TCRTETB#Tetracycline resistance protein TetB signature.

		          Length = 458

		

		 Score = 27.9 bits (62), Expect = 0.033

		 Identities = 21/122 (17%), Positives = 46/122 (37%), Gaps = 18/122 (14%)

		

		Query: 94  VLFIFGFFTLLTSIVNLASS--QPSVYGLTTLVLGSIVGGLSFYALYHFIYRFYGPDKDR 151

		           ++ +  F   +  I  +      P +      ++G + GG+ F  +  F+          

		Sbjct: 227 IVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFV---------- 276

		

		Query: 152 SQRPKLLKSILTMAAA------ILLWSMSIVLTSLLPEFLNPRLSNVVVAIVGAITLVLR 205

		           S  P ++K +  ++ A      I   +MS+++   +   L  R   + V  +G   L + 

		Sbjct: 277 SMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVS 336

		

		Query: 206 FY 207

		           F 

		Sbjct: 337 FL 338

		

		

		>PF00577#Outer membrane usher protein FimD

		          Length = 878

		

		 Score = 29.0 bits (65), Expect = 0.018

		 Identities = 6/24 (25%), Positives = 12/24 (50%)

		

		Query: 90  AGVSYLRFERQATLDLSGAIVVHS 113

		            G S+    +Q    +SG ++ H+

		Sbjct: 682 IGYSHSDDIKQLYYGVSGGVLAHA 705

		

		

		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

		           signature.

		          Length = 261

		

		 Score = 28.9 bits (64), Expect = 0.042

		 Identities = 14/52 (26%), Positives = 19/52 (36%)

		

		Query: 371 SKAADHAQFARLHGLLLEEGIYLAPSQYETNFMSSAHTRADLDQTLAAFEQA 422

		           S AA  +  A         G+ LA      N +S   T  D+  +L A E  

		Sbjct: 153 SMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGSTETDMQWSLWADENG 204

		

		

		>SECA#SecA protein signature.

		          Length = 901

		

		 Score = 27.5 bits (61), Expect = 0.044

		 Identities = 13/53 (24%), Positives = 23/53 (43%), Gaps = 4/53 (7%)

		

		Query: 88  LTSNRLFDLIAQHFPDKLELTEEHFLSRQ----EQSFLLQLLEEEWQELLSAI 136

		           L    L + I     +  +  EE   +      E+  +LQ L+  W+E L+A+

		Sbjct: 730 LHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAM 782

		

		

		>ENTSNTHTASED#Enterobactin synthetase component D signature.

		          Length = 234

		

		 Score = 26.1 bits (57), Expect = 0.035

		 Identities = 19/69 (27%), Positives = 30/69 (43%), Gaps = 14/69 (20%)

		

		Query: 44  KRKIEFLAGRWAAKEAFSKAWGTGIGKLRFQDLEILNDRQGAPYFSRSPFTGKVWISLSH 103

		           KRK E LAGR AA  A        + ++  + +  + D+   P     P    ++ S+SH

		Sbjct: 45  KRKAEHLAGRIAAVHA--------LREVGVRTVPGMGDK-RQP---LWP--DGLFGSISH 90

		

		Query: 104 AAGLVTASV 112

		            A    A +

		Sbjct: 91  CATTALAVI 99

		

		

		>ALARACEMASE#Alanine racemase signature.

		          Length = 356

		

		 Score =  361 bits (929), Expect = e-126

		 Identities = 129/368 (35%), Positives = 191/368 (51%), Gaps = 19/368 (5%)

		

		Query: 6   LHRPSKAVIDLAAIAFNIRQLSAHLPQKTEKWAVVKANAYGHGAIEVSKHIDPLVDGFCV 65

		           + RP +A +DL A+  N+  +          W+VVKANAYGHG   +   I    DGF +

		Sbjct: 1   MTRPIQASLDLQALKQNLSIVRQAATH-ARVWSVVKANAYGHGIERIWSAIGA-TDGFAL 58

		

		Query: 66  SNIDEALELRSAGIGKKILVL-GVSDLAALPLARKGKVSLTVASLEWLDLALTAEEDLTG 124

		            N++EA+ LR  G    IL+L G      L +  + +++  V S   L     A      

		Sbjct: 59  LNLEEAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQNARLKAP- 117

		

		Query: 125 LNFHIKIDSGMGRIGFRDSQEAQEAIHRLQAAGAVAE-GIFTHFATADEVDHYKFEAQLA 183

		           L+ ++K++SGM R+GF+  +       +L+A   V E  + +HFA A+  D       +A

		Sbjct: 118 LDIYLKVNSGMNRLGFQPDR-VLTVWQQLRAMANVGEMTLMSHFAEAEHPDG--ISGAMA 174

		

		Query: 184 RFHQILSELDSVPPLVHASNSATSLWHSETVLNAVRLGDIIYGLNPSGTVLEL-PYEFKP 242

		           R  Q    L         SNSA +LWH E   + VR G I+YG +PSG   ++     +P

		Sbjct: 175 RIEQAAEGL---ECRRSLSNSAATLWHPEAHFDWVRPGIILYGASPSGQWRDIANTGLRP 231

		

		Query: 243 ALSLVSELVHVKEVEAGADVGYGATYTSKSQEWIGTIPLGYADGWTRDM-QGFDVLIDGQ 301

		            ++L SE++ V+ ++AG  VGYG  YT++ ++ IG +  GYADG+ R    G  VL+DG 

		Sbjct: 232 VMTLSSEIIGVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAPTGTPVLVDGV 291

		

		Query: 302 RCPIVGRVSMDQITVRLP--QAYPLGTPVVLIGNSGAETITVTDVAEKLGTINYEVVCLI 359

		           R   VG VSMD + V L       +GTPV L G    + I + DVA   GT+ YE++C +

		Sbjct: 292 RTMTVGTVSMDMLAVDLTPCPQAGIGTPVELWG----KEIKIDDVAAAAGTVGYELMCAL 347

		

		Query: 360 SDRVPRVY 367

		           + RVP V 

		Sbjct: 348 ALRVPVVT 355

		

		

		>SECA#SecA protein signature.

		          Length = 901

		

		 Score = 30.2 bits (68), Expect = 0.032

		 Identities = 33/161 (20%), Positives = 64/161 (39%), Gaps = 11/161 (6%)

		

		Query: 195 KDLADYKQALRRVKFEELFYFQMQLQVLKRETKAVSNGLKIDWQLDAVAEKKKSLPFELT 254

		           + L   ++ +  +   E    ++  + LK +T      L+    L+ +  +  ++  E  

		Sbjct: 16  RTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVLENLIPEAFAVVRE-- 73

		

		Query: 255 SAQERSLTEILQDLRSPGHMNRLLQGDV-----GSGKTVVAGLAMYAVYTAGYQSALMVP 309

		            A +R       D++  G M  L +  +     G GKT+ A L  Y     G    ++  

		Sbjct: 74  -ASKRVFGMRHFDVQLLGGM-VLNERCIAEMRTGEGKTLTATLPAYLNALTGKGVHVVTV 131

		

		Query: 310 TEILAEQHFDSLTQLFPELKLA--LLTGGMKTAERRETLSA 348

		            + LA++  ++   LF  L L   +   GM    +RE  +A

		Sbjct: 132 NDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAA 172

		

		

		>STREPTOPAIN#Streptopain (C10) cysteine protease family signature.

		          Length = 398

		

		 Score = 28.5 bits (63), Expect = 0.010

		 Identities = 27/104 (25%), Positives = 45/104 (43%), Gaps = 17/104 (16%)

		

		Query: 43  DTRALQSVSTFDADVYEDLQEDAKKL------TAELKEKAQKSGIKYVDIVIEMGNPKTL 96

		           D    +++++F     E ++E  KKL      TAE+K+   KS +    I    GNP  L

		Sbjct: 110 DANGKENIASFMESYVEQIKE-NKKLDTTYAGTAEIKQPVVKSLLDSKGIHYNQGNPYNL 168

		

		Query: 97  LATDIPEEHKVDLIMVG---ATGLNAFERLLVGSSSEYILRHAK 137

		           L   I +    +   VG   ATG        V +++  I+++  

		Sbjct: 169 LTPVIEKVKPGEQSFVGQHAATG-------CVATATAQIMKYHN 205

		

		

		>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature.

		          Length = 1541

		

		 Score = 53.9 bits (129), Expect = 3e-09

		 Identities = 40/226 (17%), Positives = 85/226 (37%), Gaps = 18/226 (7%)

		

		Query: 99   QAEANRAQEAADKAGPEAIET-AKQEESNQKAQVDSNKSELAKADQATKTAEAERDAQAA 157

		              + N+  +  +   P  I+       SN +     +++ +     AT +   E  A+ +

		Sbjct: 985  VEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENS 1044

		

		Query: 158  KTKEAQEQAKTQEGRLAKAQNDVKEAQANLSGNATAKAEKNVKAAQEKVAADQSAVETAQ 217

		            K +    +   Q+     AQN               +A+ NVKA  +     QS  ET +

		Sbjct: 1045 KQESKTVEKNEQDATETTAQN----------REVAKEAKSNVKANTQTNEVAQSGSETKE 1094

		

		Query: 218  AKVATARQTDSQKQAEVAKAQTNQTQ--AKTARDASQKNLQEKTAAAEKTQSDLNQAQQA 275

		             +    ++T + ++ E AK +T +TQ   K     S K  Q +T   +   +  N     

		Sbjct: 1095 TQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVN 1154

		

		Query: 276  LQKAQAGKITTEASSNKNRVSMTPEYIAALRELIAPNLSEQKTNEI 321

		            +++ Q+   TT  +    + +      + + + +  + +    N +

		Sbjct: 1155 IKEPQSQTNTTADTEQPAKETS-----SNVEQPVTESTTVNTGNSV 1195

		

		

		>HTHTETR#TetR bacterial regulatory protein HTH signature.

		          Length = 215

		

		 Score = 65.8 bits (160), Expect = 2e-15

		 Identities = 21/74 (28%), Positives = 34/74 (45%)

		

		Query: 8  ILDTAQKLFMEQGFDQTSISQILEATQIARGTLYYYFSSKEEIMDAIIERTIEQAFTASQ 67

		          ILD A +LF +QG   TS+ +I +A  + RG +Y++F  K ++   I E +         

		Sbjct: 16 ILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELEL 75

		

		Query: 68 AFANNRELTVLERL 81

		           +        L  L

		Sbjct: 76 EYQAKFPGDPLSVL 89

		

		

		>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature.

		          Length = 1541

		

		 Score = 48.1 bits (114), Expect = 3e-07

		 Identities = 26/148 (17%), Positives = 50/148 (33%), Gaps = 2/148 (1%)

		

		Query: 43   ADDVKQVAVQEPAAAQDSGSGQPVQVQANSASQLEAEKATSADKVTDAAVASEKTAETAA 102

		            A++ KQ +       QD+        +    ++   +  T  ++V  +   +++T  T  

		Sbjct: 1041 AENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTE- 1099

		

		Query: 103  NTEAAAQTDAQEPAKPAEAATTEKAAVAEEAKAANATSETAKPEATNQDRQASPATADKQ 162

		             T+  A  + +E AK     T E   V  +       SET +P+A             + 

		Sbjct: 1100 -TKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEP 1158

		

		Query: 163  AKKTVTDKIVANPKVAKKDRLPEPAQRQ 190

		              +T T      P       + +P    

		Sbjct: 1159 QSQTNTTADTEQPAKETSSNVEQPVTES 1186

		

		

		

		 Score = 31.2 bits (70), Expect = 0.040

		 Identities = 22/130 (16%), Positives = 43/130 (33%), Gaps = 14/130 (10%)

		

		Query: 52   QEPAAAQDSGSGQPVQVQANSASQLEAEKATSADKVTDAAVASEKTAETAANTEAAAQTD 111

		             E    Q + + +   V+    +++E EK     KVT      ++ +ET           

		Sbjct: 1090 SETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSET--------VQP 1141

		

		Query: 112  AQEPAKPAEAATTEKAAVAEEAKAANATSETAKPEATNQDRQASPATADKQAKKTVTDKI 171

		              EPA+  +     K   ++     N T++T +P               +       + +

		Sbjct: 1142 QAEPARENDPTVNIKEPQSQT----NTTADTEQPAKET--SSNVEQPVTESTTVNTGNSV 1195

		

		Query: 172  VANPKVAKKD 181

		            V NP+     

		Sbjct: 1196 VENPENTTPA 1205

		

		

		>TCRTETA#Tetracycline resistance protein signature.

		          Length = 399

		

		 Score = 32.1 bits (73), Expect = 0.004

		 Identities = 55/343 (16%), Positives = 114/343 (33%), Gaps = 41/343 (11%)

		

		Query: 74  RWLIHFGYLQVLLFVLVAFMTRSSSYLAFSAVCLMNILSDIISDYRSGLQMPILKKNV-- 131

		                FG   VLL  L        + +A +    +  +  I++   +G    +    +  

		Sbjct: 65  ALSDRFGRRPVLLVSLAGA-AVDYAIMATAPFLWVLYIGRIVAGI-TGATGAVAGAYIAD 122

		

		Query: 132 --PEKDLMEAFSFTQLISFLCSLAGQALGVWLLTVSQQ-DFFLVALVNALTFLLSSTILY 188

		                +    F F         +AG  LG  +   S    FF  A +N L FL    +L 

		Sbjct: 123 ITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLL- 181

		

		Query: 189 LVRRRLTHDPVVISEKNAPLKEELKKMYTSSKLIFDQEGSSNFLKLLAQILIVNAMAGSL 248

		                   +      +  PL+ E      S +        +  + +   + +V  +  +L

		Sbjct: 182 -------PESHKGERR--PLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAAL 232

		

		Query: 249 IALYNLYLLDNPIFQLSFSQSLLVLQTTLVLAIIAASLTPNDYFSRLSLNQLTLWA---- 304

		             ++           +  S +   +  +L  A+I   +      +RL   +  +      

		Sbjct: 233 WVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVA-----ARLGERRALMLGMIAD 287

		

		Query: 305 --ALTMILLAVSNFLHLPVFVGIAFGFLLAYISGKINPKINTLLLSKLPSDVLAQTSSFL 362

		                ++  A   ++  P+ V +A G       G   P +  +L  ++  +   Q    L

		Sbjct: 288 GTGYILLAFATRGWMAFPIMVLLASG-------GIGMPALQAMLSRQVDEERQGQLQGSL 340

		

		Query: 363 SLLFSFSVPFGTMVFS-----SLALWNMNASWLIFIIIGVIAL 400

		           + L S +   G ++F+     S+  WN   +W+    + ++ L

		Sbjct: 341 AALTSLTSIVGPLLFTAIYAASITTWN-GWAWIAGAALYLLCL 382

		

		

		>PERTACTIN#Pertactin signature.

		          Length = 922

		

		 Score = 29.7 bits (66), Expect = 0.032

		 Identities = 13/38 (34%), Positives = 23/38 (60%)

		

		Query: 41  ILAYNPVFEVRYENGRLTKNGQVIEADPLDYLHELAVK 78

		           +L  NP  E+R++NG +T +GQ+ +     +L  + VK

		Sbjct: 79  VLLENPAAELRFQNGSVTSSGQLFDEGVRRFLGTVTVK 116

		

		

		>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family

		           signature.

		          Length = 290

		

		 Score = 72.5 bits (178), Expect = 2e-17

		 Identities = 56/261 (21%), Positives = 94/261 (36%), Gaps = 44/261 (16%)

		

		Query: 4   LYLFIIGTVFASFLGLVIDRFP-------------------------EQSIITPASHCNA 38

		             +F+   +  SFL +VI R P                           +++ P S C  

		Sbjct: 17  SLVFLFSLMIGSFLNVVIHRLPIMLEREWQAEYRSYFNPDDEGVDEPPYNLMVPRSCCPH 76

		

		Query: 39  CGKRLAPRDLIPIFSQVMNRLRCRFCGDKIPLRYLFFESILGGLFLASSL----GTISIS 94

		           C   +   + IP+ S +  R RCR C   I  RY   E +   L +A ++    G  +++

		Sbjct: 77  CNHPITALENIPLLSWLWLRGRCRGCQAPISARYPLVELLTALLSVAVAMTLAPGWGTLA 136

		

		Query: 95  QLLLLTMGLTLAIYDQREQQYP-------LMVWLVFHLLL--------IVTASINLLMLF 139

		            LLL  + + L   D  +   P       L   L+F+LL         ++ A    L+L+

		Sbjct: 137 ALLLTWVLVALTFIDLDKMLLPDQLTLPLLWGGLLFNLLGGFVSLGDAVIGAMAGYLVLW 196

		

		Query: 140 FLALGLLAFFCNLRIGAGDFLFLASCSAIFSLTEILILIQIASFAGLACFCFKKKKDRLA 199

		            L            +G GDF  LA+  A      + I++ ++S  G              

		Sbjct: 197 SLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALPIVLLLSSLVGAFMGIGLILLRNHH 256

		

		Query: 200 FVPCLLFGVVVIISYKSLLFY 220

		               + FG  + I+    L +

		Sbjct: 257 QSKPIPFGPYLAIAGWIALLW 277

		

		

		>HELNAPAPROT#Helicobacter neutrophil-activating protein A family

		           signature.

		          Length = 153

		

		 Score =  159 bits (404), Expect = 6e-53

		 Identities = 38/143 (26%), Positives = 82/143 (57%), Gaps = 2/143 (1%)

		

		Query: 24  TKAILNQVVADLYTAHIALHQVHWYMRGAGFMVWHPKMDEYMETLDTTLDEVSERLITLG 83

		            +  LN  +++ +  +  LH+ HWY++G  F   H K +E  +    T+D ++ERL+ +G

		Sbjct: 13  VENSLNTQLSNWFLLYSKLHRFHWYVKGPHFFTLHEKFEELYDHAAETVDTIAERLLAIG 72

		

		Query: 84  GKPYSTLTEFIQHSKIEEKAGEFSKNVEESLARVIEIFRYLTGLYQEALDVTDQEGDDVT 143

		           G+P +T+ E+ +H+ I +   E   +  E +  ++  ++ ++   +  + + ++  D+ T

		Sbjct: 73  GQPVATVKEYTEHASITDGGNE--TSASEMVQALVNDYKQISSESKFVIGLAEENQDNAT 130

		

		Query: 144 NDIFVGAKADLEKTIWMLTAEIG 166

		            D+FVG   ++EK +WML++ +G

		Sbjct: 131 ADLFVGLIEEVEKQVWMLSSYLG 153

		

		

		>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature.

		          Length = 1541

		

		 Score = 31.6 bits (71), Expect = 0.006

		 Identities = 25/210 (11%), Positives = 63/210 (30%), Gaps = 12/210 (5%)

		

		Query: 164  QQNFQGQQFGQQPYNQGLNYEKQPQQGGFQGQQFGQSQQPVQNQPFGQQPQQGGFQGQQF 223

		                  +   Q+      N +   +      +   +++  V+     Q  +      +  

		Sbjct: 1036 TTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANT--QTNEVAQSGSETK 1093

		

		Query: 224  GQQPQQPVQNQSFGQQPQQPVQNQQFGQQPQQGGFQGQQFGQQPQQPVQNQPFGQQPQQA 283

		              Q  +  +  +  ++ +  V+ ++  + P+       +  Q      Q +P  +     

		Sbjct: 1094 ETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTV 1153

		

		Query: 284  GFQDQQFGQQPQ----QSVSEQSQAVEQAESVQNPFTA-----ETPEQSTPQDFGTQAPV 334

		              ++ Q          Q   E S  VEQ  +            E PE +TP         

		Sbjct: 1154 NIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTV-N 1212

		

		Query: 335  QDNPFVSSVQEEQTSTPAENSVDDATENQE 364

		             ++      +  ++     ++V+ AT +  

		Sbjct: 1213 SESSNKPKNRHRRSVRSVPHNVEPATTSSN 1242

		

		

		>BLACTAMASEA#Beta-lactamase class A signature.

		          Length = 286

		

		 Score = 45.6 bits (108), Expect = 1e-07

		 Identities = 22/109 (20%), Positives = 43/109 (39%), Gaps = 21/109 (19%)

		

		Query: 153 DLTTGKT---------FAMNDTQPMTAGSTYKLPLNMLVVDEVVAGKLSMDERFDITNTN 203

		           DL +G+T         F M         ST+K+ L   V+  V AG   ++ +      +

		Sbjct: 46  DLASGRTLTAWRADERFPMM--------STFKVVLCGAVLARVDAGDEQLERKIHYRQQD 97

		

		Query: 204 Y-EYRGEHDNYVGAFNGAMRISDMQEYSLVYSENTPAYALAERLGGMEK 251

		             +Y    + ++      M + ++   ++  S+N+ A  L   +GG   

		Sbjct: 98  LVDYSPVSEKHLA---DGMTVGELCAAAITMSDNSAANLLLATVGGPAG 143

		

		

		>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase

		           signature.

		          Length = 572

		

		 Score = 27.1 bits (60), Expect = 0.003

		 Identities = 12/40 (30%), Positives = 20/40 (50%)

		

		Query: 14  EQFNFITNLLGIKDPNIIILDVLDAGTHKEIIALNIKKEM 53

		           EQF     ++   D   +++  LD G  KE+  L + KE+

		Sbjct: 313 EQFEAYKEVVQRMDGKPVVIRTLDIGGDKELSYLQLPKEL 352

		

		

		>OUTRSURFACE#Outer surface protein signature.

		          Length = 273

		

		 Score = 34.1 bits (78), Expect = 8e-04

		 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 3/87 (3%)

		

		Query: 392 TAHETIVNAK-DGKLIQSKQH-TIVEKTVTVEKEVSPSSSAASTPADNSSTAGTGNTGAA 449

		            A E + N   +GK+   K    + E TVT+ KE++ S        D ++T  T  TGA 

		Sbjct: 157 KAKEVLKNFTLEGKVANDKVTLEVKEGTVTLSKEIAKSGEVTVALNDTNTTQATKKTGAW 216

		

		Query: 450 GSTGANTATVQTPSQNSSSHTTDTDDS 476

		            S   +T T+   S+ ++       D+

		Sbjct: 217 DSK-TSTLTISVNSKKTTQLVFTKQDT 242

		

		

		>MECHCHANNEL#Bacterial mechano-sensitive ion channel signature.

		          Length = 136

		

		 Score =  101 bits (252), Expect = 8e-31

		 Identities = 51/135 (37%), Positives = 76/135 (56%), Gaps = 12/135 (8%)

		

		Query: 1   MLKDLKEFLLRGNVIDLAVGVIIANAFGAIVTSLITDVITPLFLNPILKAANLEQ----- 55

		           ++K+ +EF +RGNV+DLAVGVII  AFG IV+SL+ D+I P  L  ++   + +Q     

		Sbjct: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPP-LGLLIGGIDFKQFAVTL 61

		

		Query: 56  ---ISQLKWNGIAYGNFLSAVINFLVIGTVLFFIVKSAEKAQSLAKKKEEVEEAPAGPTE 112

		                 +    + YG F+  V +FL++   +F  +K   K   L +KKEE   APA   E

		Sbjct: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINK---LNRKKEEPAAAPAPTKE 118

		

		Query: 113 LEVLQEIKALLAEKK 127

		             +L EI+ LL E+ 

		Sbjct: 119 EVLLTEIRDLLKEQN 133

		

		

		>PF00577#Outer membrane usher protein FimD

		          Length = 878

		

		 Score = 37.1 bits (86), Expect = 7e-04

		 Identities = 30/284 (10%), Positives = 87/284 (30%), Gaps = 12/284 (4%)

		

		Query: 827  TSASVSASTSASTSASVSASTSASTSASVSASTSASTSASVSASTSASTSASVSASASAS 886

		             + +     +     ++S   + + S     S     S     + S + S +        

		Sbjct: 421  RAFNFGIGKNMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYR 480

		

		Query: 887  TSASVSASTSASTSASVSASTSASTSASVSASTSASTSASVSASTSASTSASVSASTSAS 946

		             S S   + + +T + ++     +    +      +   +++ +       +V+     +

		Sbjct: 481  YSTSGYFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRT 540

		

		Query: 947  TSASVSAST-------SASTSASVSASTS-ASTSASVSASTSASTSASVSASTSASTSAS 998

		            ++  +S S        +         +T+    + ++S S +   +         + + +

		Sbjct: 541  STLYLSGSHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLT-KNAWQKGRDQMLALNVN 599

		

		Query: 999  VSASTSASTSASVSASTSASTSASVSASTSASTSASVSASTSASTSASVSASTSASTSAS 1058

		            +  S     S S S    AS S S+S   +   +       +     ++S S     +  

		Sbjct: 600  IPFSHWLR-SDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGG 658

		

		Query: 1059 VSASTSASTSASVSASTS-ASTSASVSASTSASTSASVSASTSA 1101

		               ++ ++  A+++      + +   S S           S   

		Sbjct: 659  GDGNSGSTGYATLNYRGGYGNANIGYSHS-DDIKQLYYGVSGGV 701

		

		

		>SECYTRNLCASE#Preprotein translocase SecY subunit signature.

		          Length = 437

		

		 Score =  147 bits (373), Expect = 3e-42

		 Identities = 92/394 (23%), Positives = 178/394 (45%), Gaps = 34/394 (8%)

		

		Query: 2   KSFFKPVIIKKFLWTLFFLFIYVLGTKLTLPFVDMSKAAA----MDGTSTTLNYATALMG 57

		           ++F  P + KK L+TL  + +Y +GT + +P VD            G            G

		Sbjct: 7   RAFRTPDLRKKLLFTLAIIVVYRVGTHIPIPGVDYKNVQQCVREASGNQGLFGLVNMFSG 66

		

		Query: 58  GNLRSMSLFSVGLSPWMSSMLIWQMFAVSKRLGLSKLPLEVQERRR------MLLTLVIA 111

		           G L  +++F++G+ P++++ +I Q+  V     L  L  E Q            LT+ +A

		Sbjct: 67  GALLQITIFALGIMPYITASIILQLLTVVIP-RLEALKKEGQAGTAKITQYTRYLTVALA 125

		

		Query: 112 LIQSVALVLNLPLQEAAG---------VDMTTIMVLDTLVLM-AGTYFLIWLTDLNAAMG 161

		           ++Q   LV         G          D +    +  ++ M AGT  ++WL +L    G

		Sbjct: 126 ILQGTGLVATARSAPLFGRCSVGGQIVPDQSIFTTITMVICMTAGTCVVMWLGELITDRG 185

		

		Query: 162 LG-GSIMIVMASMIAYIPQDIWNSIQELKISSLWLALMLVFSLVFLYLAVTV--ERSKYR 218

		           +G G  +++  S+ A  P  +W   ++  ++  W+    V ++  + +A+ V  E+++ R

		Sbjct: 186 IGNGMSILMFISIAATFPSALWAIKKQGTLAGGWIEFGTVIAVGLIMVALVVFVEQAQRR 245

		

		Query: 219 IPVNKINIHNRFKKY----SYLDIRLNPAGGMPIMYAMTLVSIPQYFLLIIHFLQPENQL 274

		           IPV         + Y    +Y+ +++N AG +P+++A +L+ IP             N  

		Sbjct: 246 IPVQYAKRMIGRRSYGGTSTYIPLKVNQAGVIPVIFASSLLYIPALVAQ----FAGGNSG 301

		

		Query: 275 IEQWIE--ALSMGSPAWFILYLLTIFILALAFAFINISGDQIAERMQKSGEYIENVYPGG 332

		            + W+E        P + + Y L I   A  +  I+ + +++A+ M+K G +I  +  G 

		Sbjct: 302 WKSWVEQNLTKGDHPIYIVTYFLLIVFFAFFYVAISFNPEEVADNMKKYGGFIPGIRAGR 361

		

		Query: 333 ATRRYINGLVTYFALVGAFYLILISGLPMMVVLV 366

		            T  Y++ ++      G+ YL LI+ +P M ++ 

		Sbjct: 362 PTAEYLSYVLNRITWPGSLYLGLIALVPTMALVG 395

		

		

		>SECA#SecA protein signature.

		          Length = 901

		

		 Score =  736 bits (1902), Expect = 0.0

		 Identities = 306/836 (36%), Positives = 471/836 (56%), Gaps = 71/836 (8%)

		

		Query: 3   KNHFQIQRLKKILAKVKSFESEMAGLTDAELRKKTQEFKERLAAGETLDDLLPEAYAVVR 62

		           +N   ++R++K++  + + E EM  L+D EL+ KT EF+ RL  GE L++L+PEA+AVVR

		Sbjct: 13  RNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVLENLIPEAFAVVR 72

		

		Query: 63  EADKRVLGMFPYDVQVMGAIVLHEGNVAEMATGEGKTLTATMPLYLNALSGQGAMLVTTN 122

		           EA KRV GM  +DVQ++G +VL+E  +AEM TGEGKTLTAT+P YLNAL+G+G  +VT N

		Sbjct: 73  EASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNALTGKGVHVVTVN 132

		

		Query: 123 TYLALRDAQEMGQVYRFLGLTIEAAVVADETENLTPKQKRLIYQADIVYTTNSALGFDYL 182

		            YLA RDA+    ++ FLGLT     V      +    KR  Y ADI Y TN+  GFDYL

		Sbjct: 133 DYLAQRDAENNRPLFEFLGLT-----VGINLPGMPAPAKREAYAADITYGTNNEYGFDYL 187

		

		Query: 183 IENLAENKDSQYLSPFNYVIIDEIDSILLDSAQVPLVISGAPRVQSNFYSIMDTFITTLK 242

		            +N+A + + +     +Y ++DE+DSIL+D A+ PL+ISG     S  Y  ++  I  L 

		Sbjct: 188 RDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVNKIIPHLI 247

		

		Query: 243 EEE-----------DYHYDDEKNEVWLTSKGILAAESFL-------DLEHLFSKENQELV 284

		            +E            +  D++  +V LT +G++  E  L       + E L+S  N  L+

		Sbjct: 248 RQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYSPANIMLM 307

		

		Query: 285 RHLNLALRAHKLYKKDKDYVVRQGDKEAEVVLLDRATGRLLEMTRLQGGQHQAIEAKEHV 344

		            H+  ALRAH L+ +D DY+V+ G    EV+++D  TGR ++  R   G HQA+EAKE V

		Sbjct: 308 HHVTAALRAHALFTRDVDYIVKDG----EVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGV 363

		

		Query: 345 KLTEETRAMASITYQNLFRLFRKISGMTGTGKVVESEFMETYSMSVIKIPTNQPVIRQDL 404

		           ++  E + +ASIT+QN FRL+ K++GMTGT      EF   Y +  + +PTN+P+IR+DL

		Sbjct: 364 QIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIRKDL 423

		

		Query: 405 PDQLYQTLPEKVFASLDEVKHYHAQGNPLLIFTGSVEMSEIYSSLLLREGIAHNLLNANN 464

		           PD +Y T  EK+ A ++++K   A+G P+L+ T S+E SE+ S+ L + GI HN+LNA  

		Sbjct: 424 PDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNAKF 483

		

		Query: 465 AAREAQIIAESGQKGAVTVATSMAGRGTDIKLGP-------------------------- 498

		            A EA I+A++G   AVT+AT+MAGRGTDI LG                           

		Sbjct: 484 HANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKADWQV 543

		

		Query: 499 ---GVADLGGLVVIGTERMENQRIDLQIRGRSGRQGDPGISKFFISLEDDLLRKWGPDWL 555

		               V + GGL +IGTER E++RID Q+RGRSGRQGD G S+F++S+ED L+R +  D +

		Sbjct: 544 RHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRV 603

		

		Query: 556 KKLYKDYSTEEVQQHPVQLGQRRFRRLVAKAQRASESSAKMSRRMTLEYAQCMKIQREIT 615

		             + +    +  +   ++       + +A AQR  ES     R+  LEY      QR   

		Sbjct: 604 SGMMRKLGMKPGE--AIE--HPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAI 659

		

		Query: 616 YAERNRLIQAE---ERIDEEISRVLSQVIHQAAYEQSYETRADLYRF---ILDHFSYH-- 667

		           Y++RN L+      E I+     V    I      QS E   D+      + + F     

		Sbjct: 660 YSQRNELLDVSDVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLP 719

		

		Query: 668 -AERIPYDFDIYSPEKIAELLQDIAEQELQAKKAYLKSDKLFTHFQRVSVLKAIDENWVE 726

		            AE +  + +++  E + E +   + +  Q K+  + ++ +  HF++  +L+ +D  W E

		Sbjct: 720 IAEWLDKEPELHE-ETLRERILAQSIEVYQRKEEVVGAE-MMRHFEKGVMLQTLDSLWKE 777

		

		Query: 727 QVDYLQQLKTALSGQHFSMKNPLVEYYQEAYDGFEYMKERMKQQIVKNLLMSELAL 782

		            +  +  L+  +  + ++ K+P  EY +E++  F  M E +K +++  L   ++ +

		Sbjct: 778 HLAAMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRM 833

		

		

		>TCRTETB#Tetracycline resistance protein TetB signature.

		          Length = 458

		

		 Score = 29.1 bits (65), Expect = 0.030

		 Identities = 22/107 (20%), Positives = 44/107 (41%), Gaps = 1/107 (0%)

		

		Query: 262 GVTLGVIAGVLNLVPYLGSFLAMLPALAIGLIAGGPVMLAKVIVVFIVEQTIEGR-FVSP 320

		           G+  G +AG +++VPY+   +  L    IG +   P  ++ +I  +I    ++ R  +  

		Sbjct: 266 GIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYV 325

		

		Query: 321 LVLGSQLSIHPITILFVLLTSGTMFGIWGVFLGIPAYASAKVAIAAI 367

		           L +G             LL + + F    +   +   +  K  I+ I

		Sbjct: 326 LNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTI 372

		

		

		>INTIMIN#Intimin signature.

		          Length = 939

		

		 Score = 32.3 bits (73), Expect = 0.039

		 Identities = 50/271 (18%), Positives = 78/271 (28%), Gaps = 37/271 (13%)

		

		Query: 2310 PITVKRVDKNGT-----PVTATYIPEFTKVTPTGTGAKTEGLQGQVQEGK--VTFTPGHD 2362

		             +T +  D+NG       +T T +     V   G    T        +G   +T+T    

		Sbjct: 526  KVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVK 585

		

		Query: 2363 SVPFPAGSTPLYDNGSSVKEVPNVGKFEVDADGKVTFTPDKQFKGETPELELTRTDVNGT 2422

		                   + P+  N  S   V +      +  GK T T     K + P   +        

		Sbjct: 586  KNGVAQANVPVSFNIVSGTAVLSANSANTNGSGKATVT----LKSDKPGQVVVSAKTAEM 641

		

		Query: 2423 SVTVKYQAVV---------KEVTPTGTTATSTGPQGLPQTGTPTFKGADPLVPIDETVEP 2473

		            +  +   AV+          E+    TTA + G   +    T T K      P+      

		Sbjct: 642  TSALNANAVIFVDQTKASITEIKADKTTAVANGQDAI----TYTVKVMKGDKPVSNQEVT 697

		

		Query: 2474 TFADGSKKKTIPGQGTYTITPDGAVTFTPDKQFVGTPDPITVKRVDKNGTPV-------T 2526

		                  K        T     +G    T      G    +   RV      V        

		Sbjct: 698  FTTTLGK----LSNSTEKTDTNGYAKVTLTSTTPG--KSLVSARVSDVAVDVKAPEVEFF 751

		

		Query: 2527 ATYSPEFTKVTPTGTGTKTEGLQGQVQKGQV 2557

		             T + +   +   GTG K +     +Q GQV

		Sbjct: 752  TTLTIDDGNIEIVGTGVKGKLPTVWLQYGQV 782

		

		

		>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature.

		          Length = 1104

		

		 Score = 35.5 bits (81), Expect = 0.003

		 Identities = 60/303 (19%), Positives = 108/303 (35%), Gaps = 28/303 (9%)

		

		Query: 552  ASANGNSKAYVRAWIDFNQNGVFDENEASEFTEVTTAGDYTVNFKNNPAMTNPAVSKLGM 611

		            A    +S   V   I+F+     DE+   +  E    GD   + +           +  +

		Sbjct: 777  AVIKSDSSVIVEEEINFDGTESKDEDGEIKAYE-WDFGDGEKSNEAKATHKYNKTGEYEV 835

		

		Query: 612  RVRIALNKGDIEKPTGTAFSGEVEDLEVILTYPPKGEKKESSGIIGQPQKATLQFTPQGI 671

		            ++ +  N G I   +      E + +EVI    P  + ++++ I           + +  

		Sbjct: 836  KLTVTDNNGGINTESKKIKVVEDKPVEVINESEPNNDFEKANQIAKSNMLVKGTLSEEDY 895

		

		Query: 672  D---QNDESKKAAIDTTVAPVVLDNAGHTLTADGDG--WYNTAEGRYKVTAKGANVDVIF 726

		                  D +KK  +  T+  +       TL  +GD   +   A G      KG   +   

		Sbjct: 896  SDKYYFDVAKKGNVKITLNNLNSVGITWTLYKEGDLNNYVLYATGNDGTVLKG---EKTL 952

		

		Query: 727  EPSNGYIGTTQGIN---IRRVDTNGASTDWIAKNNGEPVINDKLNNMD----------AR 773

		            EP   Y+      N      V+  G   + + K   +  I +  NN D          ++

		Sbjct: 953  EPGRYYLSVYTYDNQSGTYTVNVKGNLKNEV-KETAKDAIKEVENNNDFDKAMKVDSNSK 1011

		

		Query: 774  YIPTVLN--FTEHRSTDAQGLSQVQDIVFNDGNPAKTPAQPSA---TNPVSFLDADGNRI 828

		             + T+ N    +  S D Q  S +  +V N  N        SA   +N V + +ADGN++

		Sbjct: 1012 IVGTLSNDDLKDIYSIDIQNPSDLNIVVENLDNIKMNWLLYSADDLSNYVDYANADGNKL 1071

		

		Query: 829  AGT 831

		            + T

		Sbjct: 1072 SNT 1074

		

		

		>GPOSANCHOR#Gram-positive coccus surface protein anchor signature.

		          Length = 539

		

		 Score = 33.9 bits (77), Expect = 0.010

		 Identities = 16/57 (28%), Positives = 28/57 (49%), Gaps = 1/57 (1%)

		

		Query: 11 RKFSIRKLNVGVCSVLLSTLLLLGAAAQVSADEASDSGAQNEVSQTGIAESSVNSAE 67

		          R +S+RKL  G  SV ++ L +LGA   V+ +E S    +++       +   +  E

		Sbjct: 8  RHYSLRKLKTGTASVAVA-LTVLGAGLVVNTNEVSAVATRSQTDTLEKVQERADKFE 63

		

		

		>GPOSANCHOR#Gram-positive coccus surface protein anchor signature.

		          Length = 539

		

		 Score = 62.8 bits (152), Expect = 5e-12

		 Identities = 69/404 (17%), Positives = 152/404 (37%), Gaps = 26/404 (6%)

		

		Query: 250 TTELKATQEKNAEAKR--RYEEKLAQASAHNKAAQAENAAIAERNQAAEKAYQEAVKRYE 307

		            T   +     ++     + +E+  +    N   + +N+ ++  N+A +    E  +   

		Sbjct: 36  NTNEVSAVATRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELS 95

		

		Query: 308 TEVSRLAQLQAEKEAVYQAALADYEKELARVQKDNAKLEQQYQSELATYQQEVERIQRAN 367

		               +L +            + + E   A ++K             +   + +E  + A 

		Sbjct: 96  NAKEKLRKNDKSLSEKASK-IQELEARKADLEKALEGAMNFST-ADSAKIKTLEAEKAAL 153

		

		Query: 368 QAAKQSYETSLAKIQEQNKEIEAQNLAVQKKNIALKEQYQADLAAYQK--NRSEIEAAND 425

		            A K   E +L      +    A+   ++ +  AL+ +      A +   N S  ++A  

		Sbjct: 154 AARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKI 213

		

		Query: 426 AKARDHQAALTAYQSELERVQAENNKRQTAYETEKAEVTARNAAIEAENAQIRQQNQEKQ 485

		                 +AAL A +++LE+         TA   +   + A  AA+EA  A++ +  +   

		Sbjct: 214 KTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAM 273

		

		Query: 486 ELYKNQLAQYEQDVARITESNQKSREAYE--KALLTYQEATARIETENKNKLAAYQAALA 543

		                  A+ +   A       +  +     + L   +++  R        L A + A  

		Sbjct: 274 NFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRR-------DLDASREAKK 326

		

		Query: 544 TYQANLARIEAENQ-------RLKEDYEANLAS---ISAQNAVIEQENASIKEKNARLKA 593

		             +A   ++E +N+        L+ D +A+  +   + A++  +E++N   +     L+ 

		Sbjct: 327 QLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRR 386

		

		Query: 594 DYDKLLEEYKKAKAAYDTAKTKYDAALVTFERELQEAEAKKNEE 637

		           D D   E  K+ + A + A +K  AAL    +EL+E++    +E

		Sbjct: 387 DLDASREAKKQVEKALEEANSKL-AALEKLNKELEESKKLTEKE 429

		

		

		

		 Score = 58.9 bits (142), Expect = 1e-10

		 Identities = 58/384 (15%), Positives = 128/384 (33%), Gaps = 28/384 (7%)

		

		Query: 114 PEEAASKRETALADYATQVKEIRETTAAYQEQLKTYEKELSQKESANQALKDQYDKALAS 173

		            +E A K E        +  ++     A ++      +ELS  +   +       +  + 

		Sbjct: 55  VQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASK 114

		

		Query: 174 YEQESSRIQAENTQLEA--DYEQKRTAYQSELSRIVKINQEKEASYQAALAAYQEERSRI 231

		            ++  +R       LE   ++    +A    L         ++A  + AL       +  

		Sbjct: 115 IQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTAD 174

		

		Query: 232 LQENAQAKADYQTAMESYTTELKATQEKNAEAKRRYEEKLAQASAHNKAAQAENAAIAER 291

		             +    +A+          EL+   E           K+    A   A  A  A + + 

		Sbjct: 175 SAKIKTLEAEKAALEARQA-ELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKA 233

		

		Query: 292 NQAAEKAYQEAVKRYETEVSRLAQLQAEKEAVYQAALADYEKELARVQKDNAKLEQQYQS 351

		            + A         + +T  +  A L+A +             EL +  +          +

		Sbjct: 234 LEGAMNFSTADSAKIKTLEAEKAALEARQ------------AELEKALEGAMNFSTADSA 281

		

		Query: 352 ELATYQQEVERIQRANQAAKQSYETSLAKIQEQNKEIEAQNLA---VQKKNIALKEQYQA 408

		           ++ T + E   ++      +   +   A  Q   ++++A   A   ++ ++  L+EQ + 

		Sbjct: 282 KIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKI 341

		

		Query: 409 DLAAYQKNRSEIEAANDAKARDHQAALTAYQSELERVQAENNKRQ------TAYETEKAE 462

		             A+ Q  R +++A+ +AK          +Q   E+ +     RQ       A    K +

		Sbjct: 342 SEASRQSLRRDLDASREAKK----QLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQ 397

		

		Query: 463 VTARNAAIEAENAQIRQQNQEKQE 486

		           V        ++ A + + N+E +E

		Sbjct: 398 VEKALEEANSKLAALEKLNKELEE 421

		

		

		

		 Score = 42.7 bits (100), Expect = 9e-06

		 Identities = 50/287 (17%), Positives = 103/287 (35%), Gaps = 14/287 (4%)

		

		Query: 79  LEVSHADLDQAVAEAEKAGVQL---KQEPPVDLGTARNPEEAASKRETALADYATQVKEI 135

		           L    ADL++A+  A           +    +       +    K      +++T     

		Sbjct: 153 LAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAK 212

		

		Query: 136 RETTAAYQEQLKTYEKELSQKESANQALKDQYDKALASYEQESSRIQAENTQLEADYEQK 195

		            +T  A +  L   + +L +               + + E E + ++A   +LE   E  

		Sbjct: 213 IKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGA 272

		

		Query: 196 RTAYQSELSRIVKINQEKEASYQAALAAYQEERSRILQENAQAKADYQTAMESYTTELKA 255

		                ++ ++I  +  EK A  +A  A  + +   +       + D   + E+   +L+A

		Sbjct: 273 MNFSTADSAKIKTLEAEKAAL-EAEKADLEHQSQVLNANRQSLRRDLDASREAK-KQLEA 330

		

		Query: 256 TQEKNAEAKR-------RYEEKLAQASAHNKAAQAENAAIAERNQAAEKAYQEAVKRYET 308

		             +K  E  +            L  +    K  +AE+  + E+N+ +E + Q   +  + 

		Sbjct: 331 EHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDA 390

		

		Query: 309 EVSRLAQLQAEKEAVYQ--AALADYEKELARVQKDNAKLEQQYQSEL 353

		                 Q++   E      AAL    KEL   +K   K + + Q++L

		Sbjct: 391 SREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKL 437

		

		

		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

		           signature.

		          Length = 261

		

		 Score = 54.3 bits (130), Expect = 9e-11

		 Identities = 37/172 (21%), Positives = 70/172 (40%), Gaps = 8/172 (4%)

		

		Query: 11  KNKKVVIIGASGSLGRVYTRAFHQAGARLYLLGRDIEKLKMFVQEFS--SFIPIS-SVDI 67

		           + K   I GA+  +G    R     GA +  +  + EKL+  V      +    +   D+

		Sbjct: 7   EGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADV 66

		

		Query: 68  TSEESLKNVVSEIQEWSECIDIVINATGFDVRKSLSAHSLEDIEQTLLINLSGAILISKI 127

		               ++  + + I+     IDI++N  G      + + S E+ E T  +N +G    S+ 

		Sbjct: 67  RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126

		

		Query: 128 FLPLLANEKGATIVHSGGFADG--RLAFPYYSVDVASRAGIFSFIESMNREL 177

		               + + +  +IV  G    G  R +   Y+   +S+A    F + +  EL

		Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYA---SSKAAAVMFTKCLGLEL 175

		

		

		>FLGFLGJ#Flagellar protein FlgJ signature.

		          Length = 313

		

		 Score = 80.1 bits (197), Expect = 6e-20

		 Identities = 58/168 (34%), Positives = 86/168 (51%), Gaps = 6/168 (3%)

		

		Query: 29  LAKHINPASANNSDQQPMNQTDYFISQIGEPARQLGQDNDLYASVMIAQAILESGSGQSG 88

		           L++ +  A   N D      +  F++Q+  PA+   Q + +   +++AQA LESG GQ  

		Sbjct: 129 LSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQAALESGWGQRQ 188

		

		Query: 89  L---SGEPHYNLFGIK--GNYDGQSANMETWEDDGEGNAYTINDSFRSYPSYVESLQDYV 143

		           +   +GEP YNLFG+K  GN+ G    + T E +  G A  +   FR Y SY+E+L DYV

		Sbjct: 189 IRRENGEPSYNLFGVKASGNWKGPVTEITTTEYE-NGEAKKVKAKFRVYSSYLEALSDYV 247

		

		Query: 144 AVLKQGHFAGAWKSNAPTYQDATAALTGVYATDTSYNAKLNYIIEKYD 191

		            +L +     A  + A   Q A A     YATD  Y  KL  +I++  

		Sbjct: 248 GLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQMK 295

		

		

		>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family

		            signature.

		          Length = 1024

		

		 Score = 86.9 bits (215), Expect = 4e-19

		 Identities = 61/227 (26%), Positives = 93/227 (40%), Gaps = 25/227 (11%)

		

		Query: 1124 EGGSGNDKLYGGAGDDTYIFDLGHGKDTIS---DNDGLSTIRFGAGIALADLQVSHPVND 1180

		              G G+DK++  AG  +     G G D +     + G  TI         +  V+  +  

		Sbjct: 615  HLGDGDDKVFLSAG--SANIYAGKGHDVVYYDKTDTGYLTIDGTKATEAGNYTVTRVLGG 672

		

		Query: 1181 SWSAVLTNTKTGDSITFSNFRFSASYRNLKLVFSDGTELGVSDEGSPFRTLYGTSESEYL 1240

		                +    K    ++         YR+ +    +G  L  +D       L GT+ ++  

		Sbjct: 673  DVKVLQEVVKE-QEVSVGKRTEKTQYRSYEFTHINGKNLTETDNLYSVEELIGTTRADKF 731

		

		Query: 1241 SSPINNLTIYAGAGNDTLNGSSGSDKLYGDKGNDELNGGDGNDLLDGGSGNDKLY----- 1295

		                     +   G+D + G+ G+D+LYGDKGND L+GG+G+D L GG GNDKL      

		Sbjct: 732  FGSKFTDIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGNGDDQLYGGDGNDKLIGVAGN 791

		

		Query: 1296 ----GGAGDDTY----------IFDLGHGKDTISDYEGLSTIRFGEG 1328

		                GG GDD +          +   G G D +   EG   +  GEG

		Sbjct: 792  NYLNGGDGDDEFQVQGNSLAKNVLFGGKGNDKLYGSEGADLLDGGEG 838

		

		

		

		 Score = 84.6 bits (209), Expect = 2e-18

		 Identities = 56/225 (24%), Positives = 89/225 (39%), Gaps = 16/225 (7%)

		

		Query: 798  ILEGGSGNDKLYGGAGDDTYIFDLGHGKDTIS---DNDGLSTIRFGAGIALADLQVSHPV 854

		                G G+DK++  AG  +     G G D +     + G  TI         +  V+  +

		Sbjct: 613  ESHLGDGDDKVFLSAG--SANIYAGKGHDVVYYDKTDTGYLTIDGTKATEAGNYTVTRVL 670

		

		Query: 855  NDSWSAVLTNTKTGDSITFSNFRFSASYRNLKLVFSDGTELGVSDEGSPFRTLYGTSESE 914

		                  +    K    ++         YR+ +    +G  L  +D       L GT+ ++

		Sbjct: 671  GGDVKVLQEVVKE-QEVSVGKRTEKTQYRSYEFTHINGKNLTETDNLYSVEELIGTTRAD 729

		

		Query: 915  YLSSPINNLTIYAGAGNDTLNGSSGSDRLYGDEGDDLLEGDSGNDLLEGGSGNDKLY--- 971

		                       +   G+D + G+ G+DRLYGD+G+D L G +G+D L GG GNDKL    

		Sbjct: 730  KFFGSKFTDIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGNGDDQLYGGDGNDKLIGVA 789

		

		Query: 972  ------GGAGDDTY-IFDLGHGKDTISDNDGLSTIRFGAGIALAD 1009

		                  GG GDD + +      K+ +    G   +    G  L D

		Sbjct: 790  GNNYLNGGDGDDEFQVQGNSLAKNVLFGGKGNDKLYGSEGADLLD 834

		

		

		

		 Score = 83.9 bits (207), Expect = 3e-18

		 Identities = 56/223 (25%), Positives = 89/223 (39%), Gaps = 16/223 (7%)

		

		Query: 962  EGGSGNDKLYGGAGDDTYIFDLGHGKDTIS---DNDGLSTIRFGAGIALADLQVSHPVND 1018

		              G G+DK++  AG  +     G G D +     + G  TI         +  V+  +  

		Sbjct: 615  HLGDGDDKVFLSAG--SANIYAGKGHDVVYYDKTDTGYLTIDGTKATEAGNYTVTRVLGG 672

		

		Query: 1019 SWSAVLTNTKTGDSITFSNFRFSASYRNLKLVFSDGTELGVSDEGSPFRTLYGTSESEYL 1078

		                +    K    ++         YR+ +    +G  L  +D       L GT+ ++  

		Sbjct: 673  DVKVLQEVVKE-QEVSVGKRTEKTQYRSYEFTHINGKNLTETDNLYSVEELIGTTRADKF 731

		

		Query: 1079 SSPINNLTIYAGAGNDTLNGSSGSDRLYGDEGDDLLEGDSGNDLLEGGSGNDKLY----- 1133

		                     +   G+D + G+ G+DRLYGD+G+D L G +G+D L GG GNDKL      

		Sbjct: 732  FGSKFTDIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGNGDDQLYGGDGNDKLIGVAGN 791

		

		Query: 1134 ----GGAGDDTY-IFDLGHGKDTISDNDGLSTIRFGAGIALAD 1171

		                GG GDD + +      K+ +    G   +    G  L D

		Sbjct: 792  NYLNGGDGDDEFQVQGNSLAKNVLFGGKGNDKLYGSEGADLLD 834

		

		

		

		 Score = 51.9 bits (124), Expect = 2e-08

		 Identities = 50/185 (27%), Positives = 74/185 (40%), Gaps = 34/185 (18%)

		

		Query: 786 GDDNVQGDKQNNILEGGSGNDKLYGGAGDDTYIFDLGHGKDTISDNDGLSTIRFGAGIAL 845

		           G+D + GDK N+ L GG+G+D+LYGG G+D  I     G + ++  DG            

		Sbjct: 754 GNDRLYGDKGNDTLSGGNGDDQLYGGDGNDKLIG--VAGNNYLNGGDG------------ 799

		

		Query: 846 ADLQVSHPVNDSWSAVLTNTKTGDSITFSNFRFSASYRNLKLVFSDGTELGVSDEGSPF- 904

		            D +     N     VL   K  D                KL  S+G +L    EG    

		Sbjct: 800 -DDEFQVQGNSLAKNVLFGGKGND----------------KLYGSEGADLLDGGEGDDLL 842

		

		Query: 905 RTLYGTSESEYLSSPINNLTIYAGAGNDTLNGSSGS--DRLYGDEGDDLLEGDSGNDLLE 962

		           +  YG     YLS   +++    G   D L+ +     D  +  EG+DL+      ++L 

		Sbjct: 843 KGGYGNDIYRYLSGYGHHIIDDDGGKEDKLSLADIDFRDVAFKREGNDLIMYKGEGNVLS 902

		

		Query: 963 GGSGN 967

		            G  N

		Sbjct: 903 IGHKN 907

		

		

		

		 Score = 49.6 bits (118), Expect = 1e-07

		 Identities = 30/96 (31%), Positives = 45/96 (46%), Gaps = 6/96 (6%)

		

		Query: 786 GDDNVQGDKQNNILEGGSGNDKLYGGAGDDTYIFDLGHGKDTISDNDGLSTIRFGAGIAL 845

		           G+D + G +  ++L+GG G+D L GG G+D Y +  G+G   I D+ G       A I  

		Sbjct: 820 GNDKLYGSEGADLLDGGEGDDLLKGGYGNDIYRYLSGYGHHIIDDDGGKEDKLSLADIDF 879

		

		Query: 846 ADLQVSHPVND-----SWSAVLTNTKTGDSITFSNF 876

		            D+      ND         VL+     + ITF N+

		Sbjct: 880 RDVAFKREGNDLIMYKGEGNVLSIGHK-NGITFRNW 914

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score =  133 bits (337), Expect = 6e-37

		 Identities = 70/296 (23%), Positives = 125/296 (42%), Gaps = 33/296 (11%)

		

		Query: 113 EERVQSVASLTNGIVKSMNVKEGDQVE-KGTTILELDDAVTKQNVGQLENSLTEINASIA 171

		           +++     ++   I +  N+   ++      + L    A+ K  V + EN   E    + 

		Sbjct: 210 DKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELR 269

		

		Query: 172 VIQKYQADKNISIQLSDYDSLAQNAVQSLISENNLYRQQLSK--ADANLVIAQYETSLAQ 229

		           V +          QL   +S   +A +       L++ ++          I      LA 

		Sbjct: 270 VYKS---------QLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELA- 319

		

		Query: 230 KMATLTENKRKTETDLAQQHYILEHLAIKSPSTGQIASLSVSYIGQNVSSENPIATILPS 289

		                     K E              I++P + ++  L V   G  V++   +  I+P 

		Sbjct: 320 ----------KNEERQQ-------ASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPE 362

		

		Query: 290 KSELIFEAQVSDKDRADIQKDMEAVVKLQAYPYSDYGTIPGKVTYISPTAFQVKGKGMVY 349

		              L   A V +KD   I     A++K++A+PY+ YG + GKV  I+  A + +  G+V+

		Sbjct: 363 DDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVF 422

		

		Query: 350 IVRISVDKKKLH---KGVSLISGLSGTIEIKTSSRSVLDYFLDPIRDGLNGSLKEK 402

		            V IS+++  L    K + L SG++ T EIKT  RSV+ Y L P+ + +  SL+E+

		Sbjct: 423 NVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGMRSVISYLLSPLEESVTESLRER 478

		

		

		

		 Score =  101 bits (252), Expect = 2e-25

		 Identities = 41/208 (19%), Positives = 89/208 (42%), Gaps = 12/208 (5%)

		

		Query: 59  YDFMPSLLEIVERPAHIAGKWIIILIGLLVLVVLLWASLSRIDVVVVGTGEIVPEERVQS 118

		            +F+P+ LE++E P     + +   I   +++  + + L ++++V    G++    R + 

		Sbjct: 39  NEFLPAHLELIETPVSRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKE 98

		

		Query: 119 VASLTNGIVKSMNVKEGDQVEKGTTILELDDAVTKQNVGQLENSL----TEINASIAVIQ 174

		           +  + N IVK + VKEG+ V KG  +L+L     + +  + ++SL     E      + +

		Sbjct: 99  IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSR 158

		

		Query: 175 KYQADKNISIQLSDYDSLAQNAVQSLISENNLYRQQLSKADANLVIAQYETSLAQKMA-- 232

		             + +K   ++L D       + + ++   +L ++Q S         Q E +L +K A  

		Sbjct: 159 SIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQK--YQKELNLDKKRAER 216

		

		Query: 233 -TLTENKRKTETD---LAQQHYILEHLA 256

		            T+     + E        +      L 

		Sbjct: 217 LTVLARINRYENLSRVEKSRLDDFSSLL 244

		

		

		>SHIGARICIN#Ribosome inactivating protein family signature.

		          Length = 289

		

		 Score = 29.4 bits (66), Expect = 0.013

		 Identities = 10/76 (13%), Positives = 26/76 (34%), Gaps = 20/76 (26%)

		

		Query: 37  ASKLKISPIIMIPGSSATENRFNRMVKKLNRNQHPHHSLVRIKVWNDGHITYRGHLKRKD 96

		             + K+  I ++  +     R+               +L+ +  + D  I+        D

		Sbjct: 49  PYERKLYDIPLLRSTLPGSQRY---------------ALIHLTNYADETISVA-----ID 88

		

		Query: 97  RNPIFVVGFQNNRDGY 112

		              ++V+G++     Y

		Sbjct: 89  VTNVYVMGYRAGDTSY 104

		

		

		>PF03544#Gram-negative bacterial tonB protein

		          Length = 243

		

		 Score = 49.6 bits (118), Expect = 1e-08

		 Identities = 18/89 (20%), Positives = 31/89 (34%), Gaps = 4/89 (4%)

		

		Query: 226 TPSQPEEPKPEVPTPTPAEPEQP-TPAPTDKPDEPTTPAEPKPEVPSVDL-PENPPINGA 283

		            P  P+E    +  P P    +P      ++P     P E +P  P  +  P  P  + A

		Sbjct: 83  IPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTA 142

		

		Query: 284 EGDLNPFAPKPEQPAEPKPETPTRPAVPE 312

		               +   P     + P+  +  +P  P 

		Sbjct: 143 TAATS--KPVTSVASGPRALSRNQPQYPA 169

		

		

		

		 Score = 48.0 bits (114), Expect = 4e-08

		 Identities = 22/111 (19%), Positives = 29/111 (26%), Gaps = 10/111 (9%)

		

		Query: 224 PTTPSQPEEPKPEVPTPTPAEPEQPTPAPTDKPDEPTTPAEPKPEVPSVDLPENPPINGA 283

		           P     P EP  E        PE P  AP         P      V          +   

		Sbjct: 63  PQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPV--------KKVEQP 114

		

		Query: 284 EGDLNPFAPKPEQPAEPKPETPTRPAVPETPGLVTTDKPSEDQIPPYVEKP 334

		           + D+ P   +P  P E     P RP         +    S    P  + + 

		Sbjct: 115 KRDVKPVESRPASPFENT--APARPTSSTATAATSKPVTSVASGPRALSRN 163

		

		

		

		 Score = 44.6 bits (105), Expect = 5e-07

		 Identities = 22/114 (19%), Positives = 31/114 (27%), Gaps = 10/114 (8%)

		

		Query: 228 SQPEEPKPEVPTPT--PAEPEQPTPAPTDKPDEPTTPAEPKPEVPSVDLPENPPINGAEG 285

		              E P P  P      A  +   P     P EP    EP+PE       E P       

		Sbjct: 39  QVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPV------ 92

		

		Query: 286 DLNPFAPKPEQPAEPKPETPTRPAVPETPGLVTTDKPSEDQIPPYVEKPAEGLE 339

		            +    PKP    +PKP         +   + +      +   P     +    

		Sbjct: 93  VIEKPKPKP--KPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATA 144

		

		

		>MALTOSEBP#Maltose binding protein signature.

		          Length = 396

		

		 Score = 68.2 bits (166), Expect = 1e-14

		 Identities = 111/407 (27%), Positives = 180/407 (44%), Gaps = 46/407 (11%)

		

		Query: 21  LAACSSNSSKESSSSKADSKTLKLWVPTGAK--DSYSDTVSKFEKESGYKVDVVEMEDPN 78

		           L+A ++     S+ +K +   L +W+  G K  +  ++   KFEK++G KV V   E P+

		Sbjct: 12  LSALTTMMFSASALAKIEEGKLVIWI-NGDKGYNGLAEVGKKFEKDTGIKVTV---EHPD 67

		

		Query: 79  A-QENLTKDASTA--ADVFSLPHDQLGKLVEAGAIQEVPSEMAEEVKKNDTEQAAIGAQY 135

		             +E   + A+T    D+    HD+ G   ++G + E+  + A + K       A+  +Y

		Sbjct: 68  KLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAV--RY 125

		

		Query: 136 KGKTYAFPYGIESQVTYYNKSKLSADDVKSYETITS---------KAKFGGNLKEANGYI 186

		            GK  A+P  +E+    YNK  L  +  K++E I +         K+    NL+E   Y 

		Sbjct: 126 NGKLIAYPIAVEALSLIYNKD-LLPNPPKTWEEIPALDKELKAKGKSALMFNLQEP--YF 182

		

		Query: 187 TAPLFLSVGDTLF----GK-DGEQVDGTNWGNEAGVNVLKFIAAQKNNSGFVNVDASNLL 241

		           T PL  + G   F    GK D + V   N G +AG+  L  +   K+ +   + D S   

		Sbjct: 183 TWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNA--DTDYSIAE 240

		

		Query: 242 AKFEDGSVDAFQSGPWDYAAAEKAVGKDNLGISVYPTVNIGGQDVQQKAFLGVKLYAVNQ 301

		           A F  G      +GPW ++  + +  K N G++V PT    GQ    K F+GV    +N 

		Sbjct: 241 AAFNKGETAMTINGPWAWSNIDTS--KVNYGVTVLPTFK--GQ--PSKPFVGVLSAGINA 294

		

		Query: 302 TPSNGDGERIAASYKLAQALTSKESQENQFKFEGRHIIPANKEVQESEDVKKDALAQAVI 361

		              N +     A   L   L + E  E   K +    + A K  +E  ++ KD    A  

		Sbjct: 295 ASPNKE----LAKEFLENYLLTDEGLEAVNKDKPLGAV-ALKSYEE--ELAKDPRIAA-- 345

		

		Query: 362 TMGSSDTYTTVMPKLSQMSVFWTESAAILSDAYNGKFGEDQYLAKLQ 408

		           TM ++     +MP + QMS FW      + +A +G+   D+ L   Q

		Sbjct: 346 TMENAQK-GEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQ 391

		

		

		>HELNAPAPROT#Helicobacter neutrophil-activating protein A family

		           signature.

		          Length = 153

		

		 Score = 26.4 bits (58), Expect = 0.046

		 Identities = 11/72 (15%), Positives = 27/72 (37%)

		

		Query: 7   KIQENFEEFMFYIDDTLDAIKQKASKQGYHLDMSLESLKDLAQFVRENDVKNDPENIDDF 66

		            + E FEE   +  +T+D I ++    G     +++   + A      +  +  E +   

		Sbjct: 45  TLHEKFEELYDHAAETVDTIAERLLAIGGQPVATVKEYTEHASITDGGNETSASEMVQAL 104

		

		Query: 67  FNSWVYLGEVFR 78

		            N +  +    +

		Sbjct: 105 VNDYKQISSESK 116

		

		

		>ADHESNFAMILY#Adhesin family signature.

		          Length = 309

		

		 Score =  233 bits (596), Expect = 9e-78

		 Identities = 79/317 (24%), Positives = 155/317 (48%), Gaps = 21/317 (6%)

		

		Query: 5   LKFSACLSLLALALCLWACQSQKESSPSSSSQGLKIVTSFYPIYSMVKAISGDLNDVR-M 63

		           +K    L +L L+  +    +      ++S Q LK+V +   I  + K I+GD  D+  +

		Sbjct: 1   MKKLGTLLVLFLSAIILVACA-SGKKDTTSGQKLKVVATNSIIADITKNIAGDKIDLHSI 59

		

		Query: 64  IQSSSGIHDFEPSANDVAAIYDADVFVYHSRTLES----WAGELNPSLKNSK-VQVLEAS 118

		           +      H++EP   DV    +AD+  Y+   LE+    W  +L  + K ++       S

		Sbjct: 60  VPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTKLVENAKKTENKDYFAVS 119

		

		Query: 119 QGMELDRVAGLEDVQAGEGVDEKTLYDPHTWLDPQKAAEEAQIIADRLSELDSDHRDTYQ 178

		            G+++            EG +EK   DPH WL+ +     A+ IA +LS  D ++++ Y+

		Sbjct: 120 DGVDVIY---------LEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSAKDPNNKEFYE 170

		

		Query: 179 ANARKFQEEAQELTERYQEIFDKVP--NKTFVTQHTAFSYLAKRFGLTQLGIAGISPEQE 236

		            N +++ ++  +L +  ++ F+K+P   K  VT   AF Y +K +G+    I  I+ E+E

		Sbjct: 171 KNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVPSAYIWEINTEEE 230

		

		Query: 237 PSPRQLTEIEDFVKEHQVKTIFVESNASSKVAQTLVKETGVQIK---ELNPLEADPANQL 293

		            +P Q+  + + +++ +V ++FVES+   +  +T+ ++T + I      + +        

		Sbjct: 231 GTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQIFTDSIAEQGKEGD 290

		

		Query: 294 SYLENLEKNLAVLAKDL 310

		           SY   ++ NL  +A+ L

		Sbjct: 291 SYYSMMKYNLDKIAEGL 307

		

		

		>BCTLIPOCALIN#Bacterial lipocalin signature.

		          Length = 171

		

		 Score = 26.5 bits (58), Expect = 0.041

		 Identities = 14/56 (25%), Positives = 28/56 (50%), Gaps = 2/56 (3%)

		

		Query: 101 YRLDQGVSQAEAKSIAKENGAGTIDKVTMGYFQDQPIWEVKSGGTYYLIGFESGQL 156

		           +  ++G+SQ  A+   + +G   I  +  GY +++  W+   G  Y++ G   G L

		Sbjct: 46  HSFERGLSQVTAEYRVRNDGG--ISVLNRGYSEEKGEWKEAEGKAYFVNGSTDGYL 99

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 38.3 bits (89), Expect = 8e-05

		 Identities = 33/229 (14%), Positives = 74/229 (32%), Gaps = 38/229 (16%)

		

		Query: 28  TDRLSQGCDYLIATLDSGELMGAAYTAGKGLFSEIIIPAIKKLQAAVDD--------IQT 79

		            D L      L A L+       + +       E+ +P     Q   ++        I+ 

		Sbjct: 134 ADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKE 193

		

		Query: 80  ELNSYRVADAQVAEYGNLDLDQLKKTKELREQQLASVKKAIEAKESFLERMKSIATFNIV 139

		           + ++++    Q      L+LD+ +  +     ++   +     ++S L+   S+     +

		Sbjct: 194 QFSTWQNQKYQ----KELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAI 249

		

		Query: 140 SHM-------------QSLVILSSAESQIESQIKELEEKIEKLEFFVAQVSQYFSDSLEV 186

		           +                 L +  S   QIES+I   +E+ + +         + ++ L+ 

		Sbjct: 250 AKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVT------QLFKNEILDK 303

		

		Query: 187 LRLAIQGASQLSQVL--ADSDGNYS-----VDGVDMSWAIKMKGQKIET 228

		           LR        L+  L   +     S     V        +  +G  + T

		Sbjct: 304 LRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTT 352

		

		

		>ACRIFLAVINRP#Acriflavin resistance protein family signature.

		          Length = 1034

		

		 Score = 28.3 bits (63), Expect = 0.017

		 Identities = 12/46 (26%), Positives = 22/46 (47%), Gaps = 2/46 (4%)

		

		Query: 19  LIIYWSLSVIPIFVGLALMYESSRVPTLVLFS--FFLFMVLLGMGV 62

		                ++S + +F+ LA +YES  +P  V+      +  VLL   +

		Sbjct: 872 APALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATL 917

		

		

		>TYPE3IMSPROT#Type III secretion system inner membrane S protein

		           family signature.

		          Length = 354

		

		 Score = 30.9 bits (70), Expect = 0.019

		 Identities = 35/199 (17%), Positives = 67/199 (33%), Gaps = 24/199 (12%)

		

		Query: 241 KGLRD------LAQNKASVSVAFVLSAVFALIFNYTIQNSIRGDVIVLDQYLFTGASLFQ 294

		           K +RD      +A++K  VS A +++    L+            ++++         L  

		Sbjct: 12  KKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLMLIPAEQSY---LPF 68

		

		Query: 295 IIVFFMIFMALYLIFNHFLLPTMLITALVVIATIASSLKFQYRQEPILP--SDMVWLRNP 352

		                 +   + L F +   P + + AL+ IA+      F    E I P    +  +   

		Sbjct: 69  SQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDIKKINPIEGA 128

		

		Query: 353 KTLFDFLGGNYGFYAILGLVALGALYWYLRKKILP-------------GKLITVLKYQLL 399

		           K +F          +IL +V L  L W + K  L                L+  +  QL+

		Sbjct: 129 KRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLLGQILRQLM 188

		

		Query: 400 LLVLPLVFFLGVMDIFATK 418

		           ++       + + D     

		Sbjct: 189 VICTVGFVVISIADYAFEY 207

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 30.2 bits (68), Expect = 0.036

		 Identities = 8/20 (40%), Positives = 12/20 (60%)

		

		Query: 666 EVHVSEGQKVAAGDLLVTAD 685

		           E+ V EG+ V  GD+L+   

		Sbjct: 109 EIIVKEGESVRKGDVLLKLT 128

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 66.0 bits (161), Expect = 9e-15

		 Identities = 20/111 (18%), Positives = 51/111 (45%)

		

		Query: 4   RILLVENEKNLARFVSLELQKEGFLVDLAETGQEGLALAKDVDYDLLLLNYDLQDMTASD 63

		            IL+ +++  +   ++  L + G+ V +              D DL++ +  + D  A D

		Sbjct: 5   TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64

		

		Query: 64  FAQQLSLIKPASVIIVLASREEIADQQEAIQHFAVSYVVKPFIISDLVERV 114

		              ++   +P   ++V++++       +A +  A  Y+ KPF +++L+  +

		Sbjct: 65  LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGII 115

		

		

		>SECA#SecA protein signature.

		          Length = 901

		

		 Score = 27.5 bits (61), Expect = 0.050

		 Identities = 22/99 (22%), Positives = 35/99 (35%), Gaps = 19/99 (19%)

		

		Query: 5   EQINYDITKSEIEYNSLNNMNPATI---------ASNLNSEFKRIRELLIQG-------R 48

		           E  N+DI K  +EY+ + N     I          S+++     IRE + +         

		Sbjct: 635 ESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETINSIREDVFKATIDAYIPP 694

		

		Query: 49  DDIFDEWHLDT-AENLGYDFDLLFAIRLYDILGLNNNFS 86

		             + + W +    E L  DFDL   I   + L       

		Sbjct: 695 QSLEEMWDIPGLQERLKNDFDLDLPIA--EWLDKEPELH 731

		

		

		>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature.

		          Length = 1104

		

		 Score = 25.4 bits (55), Expect = 0.027

		 Identities = 10/51 (19%), Positives = 16/51 (31%), Gaps = 5/51 (9%)

		

		Query: 5   RQAMNKQLLPFESKNGNYEGEATQVLVLLSNYYADKKL---FDENTDEYGN 52

		               NK       KN +  G    +  + S+Y  + K     D   +   N

		Sbjct: 598 MGMFNKMTN--YIKNNDVSGYKDYIASMSSDYGLNDKYQDYMDSLLNNIDN 646

		

		

		>PF07132#Harpin protein (HrpN)

		          Length = 356

		

		 Score = 28.1 bits (62), Expect = 0.022

		 Identities = 15/44 (34%), Positives = 21/44 (47%)

		

		Query: 65  GGLLGAVIGLLGGPIGVLFGYGIGSLYGLAAGDTVDTAEAGLID 108

		           GGL  ++ GL GG +G   G G+GS  G   G  +     G + 

		Sbjct: 74  GGLGSSLGGLGGGLLGGGLGGGLGSSLGSGLGSALGGGLGGALG 117