>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 42.8 bits (101), Expect = 2e-06 Identities = 22/52 (42%), Positives = 29/52 (55%), Gaps = 8/52 (15%) Query: 352 TLNAAKALGIEDNVGSLLVGKQADFCLWDIATPAQLAYSYGVNPCKDVVKNG 403 T+N A A G+ +GSL VGK+AD LW+ PA +GV P V+ G Sbjct: 410 TINPAIAHGLSHEIGSLEVGKRADLVLWN---PAF----FGVKP-DMVLLGG 453 Score = 30.9 bits (70), Expect = 0.011 Identities = 18/61 (29%), Positives = 29/61 (47%), Gaps = 6/61 (9%) Query: 23 YGAITNAAMAVKDGKIAWLGPRSE---LPAFDVL---SIPVYRGKGGWITPGLIDAHTHL 76 + I A + +KDG+IA +G P ++ V G+G +T G +D+H H Sbjct: 80 HWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIVTAGGMDSHIHF 139 Query: 77 I 77 I Sbjct: 140 I 140
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 40.7 bits (95), Expect = 5e-07 Identities = 19/94 (20%), Positives = 41/94 (43%), Gaps = 6/94 (6%) Query: 71 YILFYHQQAVGKVMLDISEYRIHLVDFIII-PSMRGRGFGSAILAAIKQEAMKRQLP-VG 128 ++ + +G++ + + L++ I + R +G G+A+L + A + + Sbjct: 68 FLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLM 127 Query: 129 LSVESENTQAKKLYLQHGFKPESYSGAYESMLWR 162 L + N A Y +H F GA ++ML+ Sbjct: 128 LETQDINISACHFYAKHHFI----IGAVDTMLYS 157
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 48.4 bits (115), Expect = 4e-07 Identities = 39/180 (21%), Positives = 57/180 (31%), Gaps = 26/180 (14%) Query: 3505 AVLLAGTVSQANAA---DNWYVEGFVGQAQVDSSRRDLQPQTAAGVVTSVDDKDTAFGLS 3561 AV LAG + A AA + WY +G +Q + + G Sbjct: 9 AVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTG-------FINNNGPTHENQLGAGAF 61 Query: 3562 VGYQWTPMVAIELGYADFGNGSARIEGASLTPAQYHEQVKAVTPVLADGVMLGLRFTLLQ 3621 GYQ P V E+GY G R+ ++ A GV L + Sbjct: 62 GGYQVNPYVGFEMGYDWLG----RMPYKGSVENGAYK---------AQGVQLTAKLGYPI 108 Query: 3622 HDAWRFEVPIGLFRWQADISSTMGNSRLTTELDGTDWYAGVRFSYQVSDAWSVGLGYQYV 3681 D +G W+AD S + T G Y ++ + L YQ+ Sbjct: 109 TDDLDIYTRLGGMVWRADTKSNVYGKNHDT---GVSPVFAGGVEYAITPEIATRLEYQWT 165
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 35.3 bits (81), Expect = 3e-05 Identities = 21/79 (26%), Positives = 34/79 (43%), Gaps = 2/79 (2%) Query: 55 NNLAGCGALKWLDAEHAEIKSMRTAAPYKQQGIASKILQHLINDAKSAGVKRLSLETGSM 114 NN G ++ +A I+ + A Y+++G+ + +L I AK L LET + Sbjct: 74 NNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDI 133 Query: 115 DFFNPARLLYCKFGFEICG 133 + A Y K F I Sbjct: 134 NI--SACHFYAKHHFIIGA 150
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 102 bits (256), Expect = 2e-28 Identities = 68/248 (27%), Positives = 114/248 (45%), Gaps = 15/248 (6%) Query: 5 VLVTGSSRGIGKAIALKLAAAGFDIALHYHSNQTAADATAVEVRALGVNVSLLKFDVAER 64 +TG+++GIG+A+A LA+ G IA N + ++A + DV + Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIA-AVDYNPEKLEKVVSSLKAEARHAEAFPADVRDS 69 Query: 65 AAVKAAIEADIEANGAYYGVILNAGINRDTAFPAMTESEWDSVIHTNLDGFYNVIHPCVM 124 AA+ G ++ AG+ R ++++ EW++ N G +N V Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS-VS 128 Query: 125 PMVQGRKGGRIITLASVSGIAGNRGQVNYSASKAGIIGATKALSLELAKRKITVNCIAPG 184 + R+ G I+T+ S Y++SKA + TK L LELA+ I N ++PG Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 185 LIETDM----------VADIPKDMVEQL---VPMRRMGKPNEIAALAAFLMSDDAAYITR 231 ETDM + K +E +P++++ KP++IA FL+S A +IT Sbjct: 189 STETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITM 248 Query: 232 QVISVNGG 239 + V+GG Sbjct: 249 HNLCVDGG 256
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 35.2 bits (81), Expect = 0.001 Identities = 27/151 (17%), Positives = 51/151 (33%), Gaps = 21/151 (13%) Query: 700 LLALALGIALLLFSLNFGFKKAAVVVAVPALAALLTLATLGLTGSPLSLFHALALILIFG 759 A+ L ++ L +AVP + L T A L G ++ ++L G Sbjct: 345 FEAIMLVFLVMYLFLQNMRATLIPTIAVP-VVLLGTFAILAAFGYSINTLTMFGMVLAIG 403 Query: 760 IGIDYSL----------------FFASAQNHGKTVMMAVFMSACSTLLAFGLLAFSQTQA 803 + +D ++ + + + A+ A F +AF Sbjct: 404 LLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGST 463 Query: 804 ---IHYFGLTLSLGIGFTFLLSPLILTTTLA 831 F +T+ + + L++ LILT L Sbjct: 464 GAIYRQFSITIVSAMALSVLVA-LILTPALC 493 Score = 34.4 bits (79), Expect = 0.002 Identities = 27/155 (17%), Positives = 56/155 (36%), Gaps = 23/155 (14%) Query: 694 RLLTLKLLALALGIALLLFSLNFGFKKAAVVVAVPALAALLTLATLGLTGSPLSLFHALA 753 + L ++ + + L L +L + V+ V L + L L ++ + Sbjct: 871 QAPALVAISFVV-VFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVG 929 Query: 754 LILIFGIGIDYSLFFAS-----AQNHGKTVMMAV-----------FMSACSTLLAFGLLA 797 L+ G+ ++ + GK V+ A M++ + +L LA Sbjct: 930 LLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLA 989 Query: 798 FSQTQAIHYFGLTLSLGIGFTFLLSPLILTTTLAL 832 S G ++GIG ++ ++ T LA+ Sbjct: 990 ISNGAGS---GAQNAVGIG---VMGGMVSATLLAI 1018
>SECA#SecA protein signature. Length = 901 Score = 41.4 bits (97), Expect = 1e-05 Identities = 30/84 (35%), Positives = 39/84 (46%), Gaps = 8/84 (9%) Query: 294 MRLVQGDV-----GSGKTLVAAMAA-LQAIENGYQVAMMAPTELLAEQHATNFAAWFEPL 347 M L + + G GKTL A + A L A+ G V ++ + LA++ A N FE L Sbjct: 92 MVLNERCIAEMRTGEGKTLTATLPAYLNALT-GKGVHVVTVNDYLAQRDAENNRPLFEFL 150 Query: 348 GLKVGW-LAGKLKGKARAQSLADI 370 GL VG L G R ADI Sbjct: 151 GLTVGINLPGMPAPAKREAYAADI 174
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 75.6 bits (186), Expect = 2e-18 Identities = 29/117 (24%), Positives = 51/117 (43%), Gaps = 1/117 (0%) Query: 2 KILLAEDQAMVRGALAALLTLAGGFNITQASDGDEALGLLKQQSFDLLLTDIEMPGRTGL 61 IL+A+D A +R L L+ AG +++ S+ + DL++TD+ MP Sbjct: 5 TILVADDDAAIRTVLNQALSRAG-YDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 ELAAWLKDQHSQTKVVVITTFGRAGYIKRAIEAGVGGFLLKDAPSETLVNAIQQVMA 118 +L +K V+V++ +A E G +L K L+ I + +A Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120
>PF06580#Sensor histidine kinase Length = 349 Score = 36.8 bits (85), Expect = 1e-04 Identities = 70/379 (18%), Positives = 124/379 (32%), Gaps = 57/379 (15%) Query: 1 MTSTHLQLERKLAWVYLINLVFYL---IPLTINAYPAWKIALSFAVLIPFIASYF-WAYK 56 M STH Q + + I Y ++ F + I + AY+ Sbjct: 1 MASTHRQANKYYWYCQGIGWGVYTLTGFGFASLYGSPKLHSMIFNIAISLMGLVLTHAYR 60 Query: 57 CTQNSAYRPILMMVAIATAITPINPGSISLFTFAAFFIGF-FYPLRTCLLAIAALIGLLF 115 L M I + P A IG ++ T + + A I Sbjct: 61 SFIKRQGWLKLNMGQIILRVLP-----------ACVVIGMVWFVANTSIWRLLAFINTKP 109 Query: 116 ALNEIYDFNSYYFPLYGSGLVLGVGMFG------VAERRRHQHKLKEQQSTQEISTLAAM 169 + S F + + + FG + Q K+ ++ L A Sbjct: 110 VAFTLPLALSIIFNVVVVTFMWSLLYFGWHFFKNYKQAEIDQWKMASMAQEAQLMALKAQ 169 Query: 170 VERERIARDLHDIMGHSLSSIALKAELAEKLLAKQEYQLATIQLNELGQIARESLSQIR- 228 + + L++I + I A ++L L ++ R SL Sbjct: 170 INPHFMFNALNNIR----ALILEDPTKAREMLTS------------LSELMRYSLRYSNA 213 Query: 229 HTVSDYKHKGLADSVTQLCKLLREKGVSVELTGNIPKLPARMESQLGLIVTELVNNILRH 288 VS + DS QL + E + E N + ++ ++V LV N ++H Sbjct: 214 RQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPP---MLVQTLVENGIKH 270 Query: 289 SGASQC------IIDFIQQADRLVVEVKDNGP----SKPIAEGNGLTGIRERLDSLGG-- 336 G +Q ++ + + +EV++ G + + G GL +RERL L G Sbjct: 271 -GIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQMLYGTE 329 Query: 337 -SLSYNLEQG-YAFTVSLP 353 + + +QG V +P Sbjct: 330 AQIKLSEKQGKVNAMVLIP 348
>PF07328#T-DNA border endonuclease VirD1 Length = 144 Score = 31.9 bits (72), Expect = 0.003 Identities = 17/68 (25%), Positives = 32/68 (47%), Gaps = 4/68 (5%) Query: 506 PEQIEKVI----RDTKHTTLDSLLADIGLGNAMSIVIAQRLIGDNLENQESRDGHMMPIR 561 P +++KVI + + D+ +A++GL ++ IA R IG +EN + + Sbjct: 16 PARVDKVISVKMTEAELAEFDAQIAELGLNRNRALRIAARRIGGFVENDAKTVELLRDMS 75 Query: 562 GAEGMLVT 569 A + T Sbjct: 76 RAIAGVAT 83
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 68.2 bits (167), Expect = 8e-15 Identities = 51/221 (23%), Positives = 91/221 (41%), Gaps = 20/221 (9%) Query: 150 SGMRMEAKVHIVTC----ANDMAKNITK-SVERCGLKVDDLVFSGIASADAVLTFDEKDL 204 S M ++ C A + + + S + G + L+ +A+A + Sbjct: 100 SNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEAT 159 Query: 205 GVCIVDIGGGTTDIAVYTNGALRHCAVVPVAGNQVTNDIAKIFR------TPSSHAEQIK 258 G +VDIGGGTT++AV + + + + V + G++ I R + AE+IK Sbjct: 160 GSMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIK 219 Query: 259 VQFACARSSMVSREDSIEVPS---VGGRPSR-SMSRHTLAEVVEPRYQELFELVLKELKD 314 + A IEV G P +++ + + E ++ + V+ L+ Sbjct: 220 HEIGSAYPG--DEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQ 277 Query: 315 SGLE---DQIAAGIVLTGGTASIQGVVDIAEATFGMPVRVA 352 E D G+VLTGG A ++ + + G+PV VA Sbjct: 278 CPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVA 318
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 43.7 bits (103), Expect = 5e-08 Identities = 15/36 (41%), Positives = 27/36 (75%) Query: 4 KQTGFSLIELVIVIVILGLLAATAIPRFLNVTDDAE 39 KQ GF+L+E+++VIVI+G+LA+ +P + + A+ Sbjct: 6 KQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKAD 41
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 50.3 bits (120), Expect = 2e-10 Identities = 18/53 (33%), Positives = 31/53 (58%), Gaps = 4/53 (7%) Query: 1 MKRQQGFTLIELVVVIIILGILAVTAAPKFINLQGDARA----STIQGMKGAI 49 +Q+GFTL+E++VVI+I+G+LA P + + A S I ++ A+ Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENAL 56
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 41.9 bits (98), Expect = 2e-07 Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 1/82 (1%) Query: 8 KQAGFTLVELVTTIILISILAVVVLPRLFTQSSYSAYSLRNEFISELRQVQQKALNNTDR 67 +Q GFTL+E++ ++L+ + A +VL SA F ++LR VQQ+ L + Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQTLARFEAQLRFVQQRGLQT-GQ 60 Query: 68 CFRVTVSGTGYQVSQFSARNGA 89 F V+V +Q AR+GA Sbjct: 61 FFGVSVHPDRWQFLVLEARDGA 82
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 36.8 bits (85), Expect = 2e-05 Identities = 16/58 (27%), Positives = 31/58 (53%), Gaps = 6/58 (10%) Query: 23 QQGFTLIELVIGMLVIAIAIVMLTSMLFPQA--DRAASTLHRVRSA-ELA--HSVMNE 75 Q+GFTL+E+++ +L++ ++ M+ + FP + D AA TL R + + Sbjct: 3 QRGFTLLEMMLILLLMGVSAGMVL-LAFPASRDDSAAQTLARFEAQLRFVQQRGLQTG 59
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 30.2 bits (68), Expect = 0.004 Identities = 12/27 (44%), Positives = 21/27 (77%), Gaps = 2/27 (7%) Query: 5 LSAVNKKSTLGFTLVEMVTVILILGIL 31 + A +K+ GFTL+E++ VI+I+G+L Sbjct: 1 MRATDKQR--GFTLLEIMVVIVIIGVL 25
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 558 bits (1440), Expect = 0.0 Identities = 317/348 (91%), Positives = 334/348 (95%), Gaps = 1/348 (0%) Query: 1 MFKKLRGIFSNDLSIDLGTANTLIYVRGEGIVLNEPSVVAIRGERGGSGQKSVAAVGTEA 60 M KK RG+FSNDLSIDLGTANTLIYV+G+GIVLNEPSVVAIR +R GS KSVAAVG +A Sbjct: 1 MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGS-PKSVAAVGHDA 59 Query: 61 KQMLGRTPGNIQAIRPMKDGVIADFYVTEKMLQHFIKQVHNNSFFRPSPRVLVCVPVGAT 120 KQMLGRTPGNI AIRPMKDGVIADF+VTEKMLQHFIKQVH+NSF RPSPRVLVCVPVGAT Sbjct: 60 KQMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGAT 119 Query: 121 QVERRAIRESAMGAGAREVYLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAIISLN 180 QVERRAIRESA GAGAREV+LIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVA+ISLN Sbjct: 120 QVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLN 179 Query: 181 GVVYSSSVRIGGDKFDDAIINYVRRNYGSLIGEATAERIKHTIGTAYPGDEVLEIEVRGR 240 GVVYSSSVRIGGD+FD+AIINYVRRNYGSLIGEATAERIKH IG+AYPGDEV EIEVRGR Sbjct: 180 GVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGR 239 Query: 241 NLAEGVPRSFTLNSNEILEALQEPLSGIVSAVMVALEQSPPELASDISERGMVLTGGGAL 300 NLAEGVPR FTLNSNEILEALQEPL+GIVSAVMVALEQ PPELASDISERGMVLTGGGAL Sbjct: 240 NLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGAL 299 Query: 301 LRDLDRLLMQETGIPVMVADDPLTCVARGGGKALEMIDMHGGDLFSEE 348 LR+LDRLLM+ETGIPV+VA+DPLTCVARGGGKALEMIDMHGGDLFSEE Sbjct: 300 LRNLDRLLMEETGIPVVVAEDPLTCVARGGGKALEMIDMHGGDLFSEE 347
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 32.7 bits (74), Expect = 0.002 Identities = 22/97 (22%), Positives = 38/97 (39%), Gaps = 6/97 (6%) Query: 237 EVLTEDGQSYARVTAQPLAALDRIRYVLLIWPSPDSGVTLPNQPTVPAADHSLIENSSKI 296 +V TE Q +VT+Q ++ V P + N PTV + + ++ Sbjct: 1113 KVETEKTQEVPKVTSQVSPKQEQSETVQ-----PQAEPARENDPTVNIKEPQ-SQTNTTA 1166 Query: 297 GSASPAEGTSADTTKPVTTPAATVAKPATETTPPATE 333 + PA+ TS++ +PVT + P T Sbjct: 1167 DTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTT 1203
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 42.0 bits (98), Expect = 2e-05 Identities = 35/177 (19%), Positives = 59/177 (33%), Gaps = 28/177 (15%) Query: 1263 AEPVVEELERKSKEIEIPEAILPVVGVERPAAPTEAQSTEAKPTETKPTETKLTEAQSTE 1322 E V E +++SK +E E + A T AQ+ E + + + Sbjct: 1037 TETVAENSKQESKTVEKNE---------QDATETTAQNREVAKEAKSNVKANTQTNEVAQ 1087 Query: 1323 VKPNDAKSEPTQAPLSPISEPQLQEAQSEALELQDIKPEEARSEESKSEEPKPSTDQIKA 1382 +++ T+ E E + +A + E + + + P +Q + Sbjct: 1088 SGSETKETQTTET-----KETATVEKEEKAKVETEKTQEVPK----VTSQVSPKQEQSET 1138 Query: 1383 PDLKLVQPQATPSPE-VPVT----PATPENQPAVEPIKQIQGDQNAHQPVAMSEQSR 1434 VQPQA P+ E P P + N A + N QPV S Sbjct: 1139 -----VQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVN 1190 Score = 38.9 bits (90), Expect = 2e-04 Identities = 30/147 (20%), Positives = 51/147 (34%), Gaps = 2/147 (1%) Query: 1293 AAPTEAQSTEAKPTETKPTETKLTEAQSTEVKPNDAKSEPTQAPLSPISEPQLQEAQSEA 1352 A + +++ E + TETK T T E ++ + + +SP + Q + Q +A Sbjct: 1085 VAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSP-KQEQSETVQPQA 1143 Query: 1353 LELQDIKPEEARSEESKSEEPKPSTDQIKAPDLKLVQPQATPSPEVPVTPATPENQPAVE 1412 ++ P E T+Q V+ T S V + EN P Sbjct: 1144 EPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVEN-PENT 1202 Query: 1413 PIKQIQGDQNAHQPVAMSEQSRRQRQS 1439 Q N+ + RR +S Sbjct: 1203 TPATTQPTVNSESSNKPKNRHRRSVRS 1229
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 69.2 bits (169), Expect = 3e-16 Identities = 51/206 (24%), Positives = 75/206 (36%), Gaps = 29/206 (14%) Query: 1 MKNTILTLAAIISLASVSVYSHAENMKNNDVAENGIYVGANYGY------LKVDGKDDFD 54 MK T + +A + +V A +N Y GA G+ ++ Sbjct: 1 MKKTAIAIA-VALAGFATVAQAAPK-------DNTWYTGAKLGWSQYHDTGFINNNGPTH 52 Query: 55 DNSDVIQGLVGYRFNQYLAIEGGYVNFGDY---GNSLSNA-ETDGYTAALKVSYPIVDRV 110 +N GY+ N Y+ E GY G G+ + A + G K+ YPI D + Sbjct: 53 ENQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPITDDL 112 Query: 111 ELYAKGGQLWYSTDYDVLGFSGNKDDEGV--FAGAGVAFKVTDRFLINAEYTWYDAGITV 168 ++Y + G + + D G D GV GV + +T EY W Sbjct: 113 DIYTRLGGMVWRADTKSNV-YGKNHDTGVSPVFAGGVEYAITPEIATRLEYQW------T 165 Query: 169 ENVSSGA--DTDTDFKQASLGVEYRF 192 N+ T D SLGV YRF Sbjct: 166 NNIGDAHTIGTRPDNGMLSLGVSYRF 191
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 86.1 bits (213), Expect = 3e-20 Identities = 73/358 (20%), Positives = 139/358 (38%), Gaps = 48/358 (13%) Query: 48 LWVGIAIGAYGLTQAVLQIPMGILSDKYGRKPIILIGLVLFAIGSLIAANADSIYGV-VF 106 WV A+ LT ++ G LSD+ G K ++L G+++ GS+I S + + + Sbjct: 52 NWV---NTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIM 108 Query: 107 GRAVQGMGAIA--AAVLALAADLTRDEQRTKVMAIIGMCIGGSFALSLLVGPIVAQHVGL 164 R +QG GA A A V+ + A E R K +IG + + +G ++A ++ Sbjct: 109 ARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHW 168 Query: 165 SGLFFLTAILAVTGMLIVQFLVPNPISHAP---KGDTLATPARLKRML-------TDPQL 214 S L + I +T +++ L KG L + + ML + + Sbjct: 169 SYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIV 228 Query: 215 FRLDAGIFILHL-----------------VLTAVFVALPLDLVDAGLVKEKHWMLYF--- 254 L IF+ H+ + V + AG V +M+ Sbjct: 229 SVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQ 288 Query: 255 --PAFVGAFFL---MVPLIIIG------VKRKNTKAMFQIALVIMIVALLAMALFSN-NL 302 A +G+ + + +II G V R+ + I + + V+ L + Sbjct: 289 LSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTS 348 Query: 303 WVLSFAVVLFFTGFNYLEASLPSLIAKFCPVGEKGSAMGVYSTSQFLGAFCGGMLGGG 360 W ++ +V G ++ + + ++++ E G+ M + + + FL G + GG Sbjct: 349 WFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGG 406 Score = 31.0 bits (70), Expect = 0.010 Identities = 18/111 (16%), Positives = 43/111 (38%) Query: 274 RKNTKAMFQIALVIMIVALLAMALFSNNLWVLSFAVVLFFTGFNYLEASLPSLIAKFCPV 333 + K + ++I + + + +L A + G A + ++A++ P Sbjct: 75 QLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPK 134 Query: 334 GEKGSAMGVYSTSQFLGAFCGGMLGGGAFQLVGAVGVFIVAVILMSIWLFL 384 +G A G+ + +G G +GG + + ++ +I + FL Sbjct: 135 ENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFL 185
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 29.2 bits (65), Expect = 0.013 Identities = 18/98 (18%), Positives = 33/98 (33%), Gaps = 4/98 (4%) Query: 125 PMGGGMPQNAGYQSAPQQAAPAQNQYAPAPQAAPAYQAPAQQQYAAPAPAQQQYGQQQAQ 184 P+ M A + P + P P+ P + P + P + + + Sbjct: 49 PISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKP----KPKPK 104 Query: 185 PQQGGYAPKPQAAPAPAYQAPAAPAQRPAPQPQQNFTP 222 P+ +P+ P PA+P + AP + T Sbjct: 105 PKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTA 142
>INTIMIN#Intimin signature. Length = 939 Score = 40.1 bits (93), Expect = 5e-05 Identities = 29/144 (20%), Positives = 54/144 (37%), Gaps = 9/144 (6%) Query: 698 NRDQDNWQGLAAWLDIRSYKIANTILIGEALETIATSANHFVFCIAPLDVERVNLNVSVD 757 N N G A + ++S K ++ + E + + V I + + D Sbjct: 610 NSANTNGSGKAT-VTLKSDKPGQVVVSAKTAEMTSALNANAV--IFVDQTKASITEIKAD 666 Query: 758 NVISNLNNKGKVEATLYHSNN-QPATGMDVSFKVNNGALFSNGADSIIVRTGSDGKASVE 816 + N + + T+ +P + +V+F G L + +T ++G A V Sbjct: 667 KTTAVANGQDAITYTVKVMKGDKPVSNQEVTFTTTLGKL-----SNSTEKTDTNGYAKVT 721 Query: 817 LTNATEGVVTVTANYKDASNVEPA 840 LT+ T G V+A D + A Sbjct: 722 LTSTTPGKSLVSARVSDVAVDVKA 745 Score = 33.5 bits (76), Expect = 0.006 Identities = 15/53 (28%), Positives = 23/53 (43%), Gaps = 3/53 (5%) Query: 777 NNQPATGMDVSFKVNNGALFSNGADSIIVRTGSDGKASVELTNATEGVVTVTA 829 N + VSF + +G + + T GKA+V L + G V V+A Sbjct: 587 NGVAQANVPVSFNIVSGTAVLSANSA---NTNGSGKATVTLKSDKPGQVVVSA 636
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 31.8 bits (72), Expect = 0.002 Identities = 22/76 (28%), Positives = 36/76 (47%), Gaps = 4/76 (5%) Query: 37 QGEISHTKRKIKILSKINITLSLLKSNEQYG--IKRLFIKIKNTVIDEVKHHILQLNNLL 94 + E+S K+ +L I +L + + RLFI I+ +IDE H L L N Sbjct: 465 RDELSVALSKVPLLGDIPYIGALFRRKSELTRRTVRLFI-IEPRIIDEGIAHHLALGNGQ 523 Query: 95 K-KKGIQLIVEVEDQA 109 + GI + E+ +Q+ Sbjct: 524 DLRTGILTVDEISNQS 539
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 25.5 bits (55), Expect = 0.035 Identities = 21/67 (31%), Positives = 35/67 (52%), Gaps = 5/67 (7%) Query: 27 VGYFPKSTTGDLYLKKVA----ALYLNDYWDILNSLSDCDIKYALNKYKNFQRYNKLIES 82 VG + S D + KK + A YL+DY++ N + + K ++ ++ Q YN+ IE+ Sbjct: 676 VGVYKDSGDKDEFAKKESVKKIAGYLSDYYNSANHIFSQEKKRKISIFRGIQAYNE-IEN 734 Query: 83 TLASSLI 89 L S I Sbjct: 735 VLKSKQI 741
>SALSPVBPROT#Salmonella virulence plasmid 65kDa B protein signature. Length = 591 Score = 327 bits (839), Expect = e-100 Identities = 173/409 (42%), Positives = 235/409 (57%), Gaps = 46/409 (11%) Query: 16 IVPLSLPKGGGAVTSMGMAPGNVGADGTASFSIPLPISAGRSGSTLTPPVAISYNSGAGN 75 I P LPKGG A++ G DG AS ++PLPISA R P +A+ Y+SG GN Sbjct: 15 ITPPFLPKGGKALSQ-------SGPDGLASITLPLPISAERG---FAPALALHYSSGGGN 64 Query: 76 GIFGLGWQLPVMRISRRTRYGVPSFDESSDDQTDQYLGPDGEVLLPLLNEEGLVIIETRT 135 G FG+GW M I+R T +GVP +++S D++LGPDGEVL+ L+ T Sbjct: 65 GPFGVGWSCATMSIARSTSHGVPQYNDS-----DEFLGPDGEVLVQTLSTGDAPNPVTCF 119 Query: 136 TFRELEFEQAYQVCRYQPRVEGSFSRIERWWRDGEPASTFWLIHDATGHLHCLGKTIAGR 195 + ++ F Q+Y V RYQPR E SF R+E +W FWL+HD+ G LH LGKT A R Sbjct: 120 AYGDVSFPQSYTVTRYQPRTESSFYRLE-YWVGNSNGDDFWLLHDSNGILHLLGKTAAAR 178 Query: 196 VASPQLLTDSYNPRIGEWLLEESVSPTGEHMIYCYQDENNVGVSPDKQYS---LGTLPHL 252 ++ PQ S+ +WL+EESV+P GEH+ Y Y EN V + + + +L Sbjct: 179 LSDPQ--AASH---TAQWLVEESVTPAGEHIYYSYLAENGDNVDLNGNEAGRDRSAMRYL 233 Query: 253 MEIRYGNLHPAANLYLWSSDNVNSATSGVEWLFKLIFDYGARGLDPHSQPQDKIEPDQHW 312 +++YGN PAA+LYLW+S AT V+WLF L+FDYG RG+DP P W Sbjct: 234 SKVQYGNATPAADLYLWTS-----ATPAVQWLFTLVFDYGERGVDPQVPP--AFTAQNSW 286 Query: 313 TARHDPFSRFDYGYEVRCHRLCRQIIMFHQNFTELNQGCPTVVGRLILDYDENAVLSRLI 372 AR DPFS ++YG+E+R HRLCRQ++MFH EL + T+V RL+L+YDEN +L++L Sbjct: 287 LARQDPFSLYNYGFEIRLHRLCRQVLMFHHFPDELGEA-DTLVSRLLLEYDENPILTQLC 345 Query: 373 GARLWAYDTDG---------KPQSQPPLFLNYTSFDTSSRPDA-WHVFQ 411 AR AY+ DG P PP + SSRP + W + + Sbjct: 346 AARTLAYEGDGYRRAPVNNMMPPPPPPPMMG----GNSSRPKSKWAIVE 390
>INTIMIN#Intimin signature. Length = 939 Score = 43.1 bits (101), Expect = 6e-06 Identities = 24/120 (20%), Positives = 42/120 (35%) Query: 745 NALANNTETNQVSVTVRDARNALVSGEEVSFSASNGATVETPTVLTNSNGVAIASIKSTQ 804 +A A+ TE + TV+ A + S A + + TN +G A ++KS + Sbjct: 569 SAKADGTEAITYTATVKKNGVAQANVPVSFNIVSGTAVLSANSANTNGSGKATVTLKSDK 628 Query: 805 SGISTITASFNGTTKTVEVTFILVNCQSLGQSLEGACIDIFDADNNGKLFTSSPSVAYLD 864 G ++A T + ++ Q+ E N T + V D Sbjct: 629 PGQVVVSAKTAEMTSALNANAVIFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKGD 688
>INTIMIN#Intimin signature. Length = 939 Score = 41.2 bits (96), Expect = 2e-05 Identities = 35/164 (21%), Positives = 55/164 (33%), Gaps = 10/164 (6%) Query: 738 VERVNLNVSVDNVTSNGAEKNTVEATLYHSNNQPATGVDVSFKVNNGALFSNGTDSIIVR 797 V + + ++G E T AT+ N V VSF + +G + + Sbjct: 558 VGVTDFTADKTSAKADGTEAITYTATV-KKNGVAQANVPVSFNIVSGTAVLSANSA---N 613 Query: 798 TGRDGKASVEVASTTEGVVTVTAIYRDSTN-LNPDYTGITKVVNINFSTYLPDNIVYEG- 855 T GKA+V + S G V V+A + T+ LN + + + D Sbjct: 614 TNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQTKASITEIKADKTTAVAN 673 Query: 856 ----ISLTPLVSYNQAVAAGLEIDSTLELGYTIAVVNHIDATKY 895 I+ T V + E+ T LG D Y Sbjct: 674 GQDAITYTVKVMKGDKPVSNQEVTFTTTLGKLSNSTEKTDTNGY 717 Score = 37.7 bits (87), Expect = 3e-04 Identities = 21/101 (20%), Positives = 39/101 (38%), Gaps = 9/101 (8%) Query: 721 VSTTNTPLLVFCIAPLDVERVNLNVSVDNVTSNGAEKNTVEATLYHSNN-QPATGVDVSF 779 S N ++F + + D T+ ++ + T+ +P + +V+F Sbjct: 642 TSALNANAVIF---VDQTKASITEIKADKTTAVANGQDAITYTVKVMKGDKPVSNQEVTF 698 Query: 780 KVNNGALFSNGTDSIIVRTGRDGKASVEVASTTEGVVTVTA 820 G L + +T +G A V + STT G V+A Sbjct: 699 TTTLGKL-----SNSTEKTDTNGYAKVTLTSTTPGKSLVSA 734
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 36.0 bits (83), Expect = 7e-04 Identities = 31/224 (13%), Positives = 68/224 (30%), Gaps = 23/224 (10%) Query: 411 QIGARYIYEDLFSADYFLG-YFSTGDIYQSANIKFGRLSLSAKAFDLDYNTRNFTLSNQL 469 +R ++ + D + D Y A K G+L L+ +T + S+Q Sbjct: 492 TTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQT 551 Query: 470 YGTNPY--KNFSISYSKPFFGGNGYLNYNNYSSKNYYGINNDNSIVIEKPIDYIYNINAL 527 Y + F + F N L+Y+ +KN + D + + I Sbjct: 552 YWGTSNVDEQFQAGLNTAFEDINWTLSYS--LTKNAWQKGRDQMLALNVNI--------- 600 Query: 528 NNVLNNALNNGSYSTISNENYNIGWSTNIYSGTLTLNSNYNSNSAYDEVKFGIYWSQRFG 587 ++ S ++ + S ++ +N + +S + G Sbjct: 601 ------PFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTG 654 Query: 588 KSVAGGLSVMTNNKGSSQYNNS---LSLNASNDNWYANHTVMAS 628 + G + + + Y ++ S+ + S Sbjct: 655 YAGGGDGNSGSTGYATLNYRGGYGNANIGYSHSDDIKQLYYGVS 698
>INTIMIN#Intimin signature. Length = 939 Score = 43.1 bits (101), Expect = 6e-06 Identities = 17/81 (20%), Positives = 32/81 (39%) Query: 743 NALANNTVTNQVSVTVRDANNAPVAGQEVIFNASNNATVVTQTVLTDGNGVAIASIRSPQ 802 +A A+ T + TV+ A S A + + T+G+G A +++S + Sbjct: 569 SAKADGTEAITYTATVKKNGVAQANVPVSFNIVSGTAVLSANSANTNGSGKATVTLKSDK 628 Query: 803 SGISTVTASFNGTTKTVDVTF 823 G V+A T ++ Sbjct: 629 PGQVVVSAKTAEMTSALNANA 649 Score = 42.4 bits (99), Expect = 1e-05 Identities = 40/148 (27%), Positives = 59/148 (39%), Gaps = 10/148 (6%) Query: 730 VDNDKSTIAVIFNNALANNTVTNQVSVTVRDANN-APVAGQEVIFNASNNATVVTQTVLT 788 + I A+AN ++ TV+ PV+ QEV F + + T T Sbjct: 656 TKASITEIKADKTTAVANGQDA--ITYTVKVMKGDKPVSNQEVTFTTTLGKLSNS-TEKT 712 Query: 789 DGNGVAIASIRSPQSGISTVTASFNGTT---KTVDVTFNCQ-SLAGACIDIFDTG-SGKL 843 D NG A ++ S G S V+A + K +V F ++ I+I TG GKL Sbjct: 713 DTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGTGVKGKL 772 Query: 844 FTNSPSVAYLNSIGGSAADGTYTETGTN 871 T +N + S +G YT N Sbjct: 773 PTVWLQYGQVN-LKASGGNGKYTWRSAN 799
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 59.6 bits (144), Expect = 5e-13 Identities = 40/203 (19%), Positives = 67/203 (33%), Gaps = 25/203 (12%) Query: 1 MRKFNLAVVIPLSIMSCSAVASYSDSSLELGVSAGQFNLKDS-----TGSYSGPSVGFNF 55 M+K +A+ + L+ + A A+ D++ G G D+ G +G Sbjct: 1 MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFINNNGPTHENQLGAGA 60 Query: 56 I--RNFNDWFSFEGNYL------SSFNMDNANYDIQASTFSLAPVFTYHINDTFSIYGKG 107 N + FE Y +++N Y Q + Y I D IY + Sbjct: 61 FGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKL--GYPITDDLDIYTRL 118 Query: 108 GASSMRITSSERNGLDFSYNTIGWFYGFGLNTSINNRINVRLGYETVTGDTGIEILGVTA 167 G R + + + G+ +I I RL Y+ +G Sbjct: 119 GGMVWRADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDAHTIGTRP 178 Query: 168 DGFSIQSSHTKISVISLGATYRF 190 D ++SLG +YRF Sbjct: 179 D----------NGMLSLGVSYRF 191
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 25.3 bits (55), Expect = 0.034 Identities = 9/42 (21%), Positives = 19/42 (45%) Query: 23 TLIITPPDYTSISKLAKIINVQNNNSSRGPIMHVVDTTSLKV 64 L + PD+++ ++A ++N PI D+ + V Sbjct: 194 VLQLRNPDFSTAVRVADVVNAFARARYGDPIAEPRDSQEIAV 235
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 49.8 bits (119), Expect = 1e-08 Identities = 38/192 (19%), Positives = 70/192 (36%), Gaps = 29/192 (15%) Query: 123 AEQDNTKAKADLDKAKSTLALAKTKLERIEDLL---IKEPFALAKQDVDELRENVNLADA 179 A + K+ L++ +S + AK + + + L I + ++ L LA Sbjct: 264 AVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLE--LAKN 321 Query: 180 DFRQKQATMNDYLIKAPFDG---QLTSFSQSIGSQIGAGTALVTLYSLN-PVEVRYAISQ 235 + RQ+ + I+AP QL ++ G + L+ + + +EV + Sbjct: 322 EERQQASV-----IRAPVSVKVQQLKVHTE--GGVVTTAETLMVIVPEDDTLEVTALVQN 374 Query: 236 NDFGKGQKGQKVNVTVEAYGNKVFKGL---VNYVAP--AVDESSG-------RVEVHAAL 283 D G GQ + VEA+ + L V + D+ G +E + Sbjct: 375 KDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCLS 434 Query: 284 -DNPEFKLAPGM 294 N L+ GM Sbjct: 435 TGNKNIPLSSGM 446 Score = 47.1 bits (112), Expect = 8e-08 Identities = 23/108 (21%), Positives = 44/108 (40%), Gaps = 7/108 (6%) Query: 105 ISAIHFSNGDKVTKGQVIAEQDNTKAKADLDKAKSTLALAKTKLERIEDLLIKEPFALAK 164 + I G+ V KG V+ + A+AD K +S+L A+ + R + L ++ Sbjct: 107 VKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILS----RSIEL 162 Query: 165 QDVDELRENVNLADADFRQKQATMNDYLIKAPFDGQLTSFSQSIGSQI 212 + EL+ + +++ LIK F T +Q ++ Sbjct: 163 NKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFS---TWQNQKYQKEL 207
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 651 bits (1680), Expect = 0.0 Identities = 301/1032 (29%), Positives = 509/1032 (49%), Gaps = 44/1032 (4%) Query: 8 IRHPIFASVLSIMAVLLGLIAFQKLDIQYFPEHTTHSASVNASIAGASADFMSSNVADKL 67 IR PIFA VL+I+ ++ G +A +L + +P + SV+A+ GA A + V + Sbjct: 6 IRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQVI 65 Query: 68 IAAASGIDKVDTM-STDCSEGRCSLTIKFNDDTS-DIEYTNLMNKLRSSVEGINDFPQSM 125 +GID + M ST S G ++T+ F T DI + NKL+ + PQ Sbjct: 66 EQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLAT---PLLPQE- 121 Query: 126 IDKPTVTDDTSATDSASNIITFVNAGGMEKQAMYDYISQQLVPQLKQVQGVGAVWGPYGG 185 + + ++ + S++ + G + + DY++ + L ++ GVG V G Sbjct: 122 VQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDV--QLFG 179 Query: 186 SQKAVRVWLNPEQMKALNIKAADVVGTLGSYNASFTSG------AIKGKSRDFSINPLNQ 239 +Q A+R+WL+ + + + DV+ L N +G A+ G+ + SI + Sbjct: 180 AQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 240 VETLEDVKDLVIKVS-EGKIIRVADVADVVMGEESLSPSILSIGGHSAMSLQILPLSNAN 298 + E+ + ++V+ +G ++R+ DVA V +G E+ + I I G A L I + AN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYN-VIARINGKPAAGLGIKLATGAN 298 Query: 299 PVTVASNIKAEIARMQQHLPQGLEMTLAYNQADFIEASIDEGFSALIEAVILVSLIVVLF 358 + A IKA++A +Q PQG+++ Y+ F++ SI E L EA++LV L++ LF Sbjct: 299 ALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLF 358 Query: 359 LGSLRAASIPIITIPVCVIGVFAVMSALGFSINVLTILAIILAIGLVVDDAIVVVENCYR 418 L ++RA IP I +PV ++G FA+++A G+SIN LT+ ++LAIGL+VDDAIVVVEN R Sbjct: 359 LQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 418 Query: 419 HI-ENGETPFNAAIKGCQEIIFPIIAMTLTLAAVYLPIGLMSGLTADLFRQFSFTLAAAV 477 + E+ P A K +I ++ + + L+AV++P+ G T ++RQFS T+ +A+ Sbjct: 419 VMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAM 478 Query: 478 MISGVVALTLSPMMSAYLINTTEQQPK-----WFSRVEHALQQLNDLYIKELDKWFTRKR 532 +S +VAL L+P + A L+ + +F + Y + K Sbjct: 479 ALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTG 538 Query: 533 LMLGAAVVLIGLAGIAYWQLPKILLPAEDSGFIDVASNGPTGVGRQYHLNHNAELNGVMD 592 L +++ + + +LP LP ED G P G ++ ++ Sbjct: 539 RYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYL 598 Query: 593 EHPAVGANLSY------IEGEPVN----HVLLKPWGERS---EGIDDVISDLMSKSKESV 639 ++ + G+ N V LKPW ER+ + VI + + Sbjct: 599 KNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIR 658 Query: 640 SAYNMSFSIRSANNLSIANNLRLELTTLDRNK---DELNDTAAKVQKLLEDYPG-LNNVG 695 + + F++ + L A EL +D+ D L ++ + +P L +V Sbjct: 659 DGFVIPFNMPAIVELGTATGFDFEL--IDQAGLGHDALTQARNQLLGMAAQHPASLVSVR 716 Query: 696 NSVLRDQLRYDLSIDRNAIILSGVSYGDVTNALSTFLGSVKAADLHATDGFTYPIQVQVN 755 + L D ++ L +D+ GVS D+ +ST LG D G + VQ + Sbjct: 717 PNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDF-IDRGRVKKLYVQAD 775 Query: 756 LDKLSDFKVLNKLYVTSESGQALPLSQFVSIKQTTAESNIKTFMGLDSAELTADVMPGYS 815 + ++KLYV S +G+ +P S F + ++ + GL S E+ + PG S Sbjct: 776 AKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTS 835 Query: 816 TDEIKAYLDEQLPTLLNDAQGFKYNGVVKDLMDSQAGTQSLFLLALVFIYLILAAQFESF 875 + + A + E L + L G+ + G+ S +L ++ V ++L LAA +ES+ Sbjct: 836 SGDAMALM-ENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESW 894 Query: 876 VDPLIILLTVPLCIVGALLTLTLFGQSVNIYSQIGLLTLVGLVTKHGILLVEFANK-QQD 934 P+ ++L VPL IVG LL TLF Q ++Y +GLLT +GL K+ IL+VEFA + Sbjct: 895 SIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEK 954 Query: 935 QGLSAIEAARSSAKSRLRPILMTSLTMILSAIPLALASGPGSLGLANIGLVLVGGLLAGT 994 +G +EA + + RLRPILMTSL IL +PLA+++G GS +G+ ++GG+++ T Sbjct: 955 EGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSAT 1014 Query: 995 FFSLFVVPVAYV 1006 ++F VPV +V Sbjct: 1015 LLAIFFVPVFFV 1026 Score = 93.4 bits (232), Expect = 2e-21 Identities = 63/362 (17%), Positives = 123/362 (33%), Gaps = 22/362 (6%) Query: 662 LELTTLDRNKDELNDTAAK-VQKLLEDYPGLNNVGNSVLRDQLRYDLSIDRNAIILSGVS 720 +D+++D A V+ L G+ +V + +R + +D + + ++ Sbjct: 142 FVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQYAMR--IWLDADLLNKYKLT 199 Query: 721 YGDVTNALS-----TFLGSVKAADLHATDGFTYPIQVQVNLDKLSDFKVLNKLYVTSESG 775 DV N L G + I Q +F + G Sbjct: 200 PVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKNPEEFG--KVTLRVNSDG 257 Query: 776 QALPLSQFVSIKQTTAESNIK-TFMGLDSAELTADVMPGYST----DEIKAYLDEQLPTL 830 + L ++ N+ G +A L + G + IKA L E P Sbjct: 258 SVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDTAKAIKAKLAELQPFF 317 Query: 831 LNDAQGFKYNGVVKDLMDSQAGTQSLF---LLALVFIYLILAAQFESFVDPLIILLTVPL 887 QG K Q + A++ ++L++ ++ LI + VP+ Sbjct: 318 ---PQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPV 374 Query: 888 CIVGALLTLTLFGQSVNIYSQIGLLTLVGLVTKHGILLVEFANK-QQDQGLSAIEAARSS 946 ++G L FG S+N + G++ +GL+ I++VE + + L EA S Sbjct: 375 VLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKS 434 Query: 947 AKSRLRPILMTSLTMILSAIPLALASGPGSLGLANIGLVLVGGLLAGTFFSLFVVPVAYV 1006 ++ ++ + IP+A G + +V + +L + P Sbjct: 435 MSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCA 494 Query: 1007 AM 1008 + Sbjct: 495 TL 496
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 300 bits (770), Expect = 4e-88 Identities = 104/553 (18%), Positives = 216/553 (39%), Gaps = 39/553 (7%) Query: 143 SDFVGKSGQA-LVDQLSQSTPECVGKLYSLKGSAATALFSEANVISVANAIATKAKDYTG 201 D + + + LV+ + + E V L++ + T + V ++ + + YT Sbjct: 95 FDELNRMNYSDLVELIKTISYENVPDLFNFNDGSYTFFSNRDRVQAIIYGLEDSGRTYTA 154 Query: 202 VDVQHLESHIYFVRAALYVQFYSPNDVPAYSSAAKASLKSALNALFANAAIWTVSDDNAG 261 D + + + + F+RA Y+ FY+ + K A+ A+ N+ + G Sbjct: 155 DDDKGIPTLVEFLRAGYYLGFYNKQLSYLNTPQLKNECLPAMKAIQYNSNFRLGTKAQDG 214 Query: 262 VLKEALILIDSAELGADFNHATIKVLMDYDANWQASFAMNAAANSVFTTLFRAQWNDDMQ 321 V++ LI +A + + I VL D+ N + + N+VF + + + Sbjct: 215 VVEALGRLIGNASADPEVINNCIYVLSDFKDNIDKYGSNYSKGNAVFNLMKGIDYYTNSV 274 Query: 322 -----ALFARDQGILDALNNFQLE------HRDLLGTNAEYLLVNSVKELSRLYYIDSMR 370 A++ + ++ + D L + +L+ N++ R+ Sbjct: 275 IYNTKGYDAKNTEFYNRIDPYMERLESLCTIGDKLNNDNAWLVNNALYYTGRMGKFREDP 334 Query: 371 PRVTQLVKNILSSTSKTEPSKVLWYAAAEMADYYDRSHCNDYNICGFKAQLEADTLPFNW 430 + ++ + + ++ S ND + KA LP + Sbjct: 335 SISQRALERAMKEYPYLSYQYIEAANDLDLNFGGKNSSGNDIDFNKIKADAREKYLPKTY 394 Query: 431 KCSDSLKI-RAQD-LYQDQAKWACDVLTSQESYFHSKLETGMQPVGQDNNDDLELVIFGS 488 D + +A D + +++ K ++ F ++ + +D L +VI+ S Sbjct: 395 TFDDGKFVVKAGDKVTEEKIKRLYWASKEVKAQFMRVVQNDKALEEGNPDDILTVVIYNS 454 Query: 489 SSEYKSLANSIFGINTDNGGMYLEGSPAGLKNQARFIAYEAEWRTPDFHVWNL-QHEYVH 547 EYK L I G +TDNGG+Y+E N F YE + + L +HE+ H Sbjct: 455 PEEYK-LNRIINGFSTDNGGIYIE-------NIGTFFTYERTPEESIYTLEELFRHEFTH 506 Query: 548 YLDGRYNLFGDFSRGTS---ANTIWWIEGLAEYIS---------YRDANTAAIAMGETGE 595 YL GRY + G + +G W+ EG AE+ + R + T +A Sbjct: 507 YLQGRYVVPGMWGQGEFYQEGVLTWYEEGTAEFFAGSTRTDGIKPRKSVTQGLAYDRNNR 566 Query: 596 FMLSTIFKNNYESGQDRIYRWGYLAVRFMFEHHRDDVRQILAYLRNDQYAEYQTFMDGIG 655 L + Y S Y +G+ +M+ ++ ++ Y++N+ + Y+ ++ + Sbjct: 567 MSLYGVLHAKYGS--WDFYNYGFALSNYMYNNNMGMFNKMTNYIKNNDVSGYKDYIASMS 624 Query: 656 TRY--DNEWQGWL 666 + Y ++++Q ++ Sbjct: 625 SDYGLNDKYQDYM 637 Score = 74.8 bits (183), Expect = 1e-15 Identities = 36/184 (19%), Positives = 63/184 (34%), Gaps = 26/184 (14%) Query: 539 WNLQHEYVHYLDGRYNLFGDFSRGTSANTIWWIEGLAEYISYRDANTAAIA-MGETGEFM 597 + L +Y Y+D N + ++ + A+ I+ + ++ + + + Sbjct: 627 YGLNDKYQDYMDSLLNNIDNLDVPLVSD-EYVNGHEAKDINEITNDIKEVSNIKDLSSNV 685 Query: 598 LSTIFKNNYESGQDRIYRWGYLAVRFMFEHH-----RDDVRQILAYLRNDQYAEYQTF-- 650 + F Y+ R Y+ R E + + IL L + Y+T Sbjct: 686 EKSQFFTTYD------MRGTYVGGRSQGEENDWKDMNSKLNDILKELSKKSWNGYKTVTA 739 Query: 651 ------MDGIGTR-YDNEWQGWLASGLSTADDGIVDKGPSDV-DAEPSGREGNWTGPAGT 702 +DG G YD + G T D V+K P V ++ S GT Sbjct: 740 YFVNHKVDGNGNYVYDVVFHGMNT---DTNTDVHVNKEPKAVIKSDSSVIVEEEINFDGT 796 Query: 703 ISKD 706 SKD Sbjct: 797 ESKD 800
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 45.3 bits (107), Expect = 3e-07 Identities = 30/162 (18%), Positives = 56/162 (34%), Gaps = 1/162 (0%) Query: 221 APAYASNLGLPPEKVATYMTATILAGLLAQWPMGKLSDIMSRSRLIRINCILLGILALAI 280 P A++ PP TA +L + GKLSD + RL+ I+ ++ Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 281 ALTPYHPVISLVMTFLFGILGFTFYPLATALANSRVEQNERVGLSATILLTFGLGASIGP 340 + + ++ F+ G F L + + + R I +G +GP Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 341 LIASTLMQWLGNSMLYGFMSACTLILFVRLRYVHSQQKVETN 382 I + ++ S L T+I L + ++ Sbjct: 157 AIGGMIAHYIHWSYLLLIPMI-TIITVPFLMKLLKKEVRIKG 197 Score = 31.0 bits (70), Expect = 0.010 Identities = 26/137 (18%), Positives = 55/137 (40%), Gaps = 12/137 (8%) Query: 213 IVGSFYGLAPAYASNLGLPPEKVATYMTATILAGLLAQWPMGKLSDIMSRSRLIRINCIL 272 ++ + L+ A ++ + P + I+ G + G L D ++ I Sbjct: 282 MMKDVHQLSTAEIGSVIIFPG-----TMSVIIFGYIG----GILVDRRGPLYVLNIGVTF 332 Query: 273 LGILALAIALTPYHP--VISLVMTFLFGILGFTFYPLATALANSRVEQNERVGLSATILL 330 L + L + +++++ F+ G L FT ++T +++S +Q G+S Sbjct: 333 LSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFT 392 Query: 331 TFGLGASIGPLIASTLM 347 +F L G I L+ Sbjct: 393 SF-LSEGTGIAIVGGLL 408
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 45.8 bits (108), Expect = 3e-07 Identities = 16/51 (31%), Positives = 26/51 (50%), Gaps = 1/51 (1%) Query: 650 SVPVNFLS-SVDTTGGNSGSPVFNGKGELVGLNFDSTYEAITKDWFFSPTI 699 + + + TTGGNSGSPVFN K E++G+++ F + + Sbjct: 220 YLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHWGGVPNEFNGAVFINENV 270
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 438 bits (1129), Expect = e-157 Identities = 160/350 (45%), Positives = 218/350 (62%), Gaps = 6/350 (1%) Query: 6 RAEISSSALQTNLAALRQQAPASRVMAVVKANGYGHGLLNVANCLVSADGFGLARLDEAL 65 +A + AL+ NL+ +RQ A +RV +VVKAN YGHG+ + + + + DGF L L+EA+ Sbjct: 6 QASLDLQALKQNLSIVRQAATHARVWSVVKANAYGHGIERIWSAIGATDGFALLNLEEAI 65 Query: 66 ELRAGGVTARLLLLEGFFRATDLPLLVGHDIDTVVHHSSQLEMLEQTVLSKPVTVWLKVD 125 LR G +L+LEGFF A DL + H + T VH + QL+ L+ L P+ ++LKV+ Sbjct: 66 TLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQNARLKAPLDIYLKVN 125 Query: 126 SGMHRLGFTPEQFSTVYDRLMACSNVAKPIHLMTHFACADEPDNTYTSVQMAAFNTLTAG 185 SGM+RLGF P++ TV+ +L A +NV + LM+HFA A+ PD MA G Sbjct: 126 SGMNRLGFQPDRVLTVWQQLRAMANV-GEMTLMSHFAEAEHPDGISG--AMARIEQAAEG 182 Query: 186 LPGFRTLANSAGALYWPQSQGDWIRPGIALYGVSPVT--GDCGANHGLVPAMELVSQLIA 243 L R+L+NSA L+ P++ DW+RPGI LYG SP D AN GL P M L S++I Sbjct: 183 LECRRSLSNSAATLWHPEAHFDWVRPGIILYGASPSGQWRDI-ANTGLRPVMTLSSEIIG 241 Query: 244 VRDHKANQPVGYGCFWTAKQDTRLGVVAIGYGDGYPRNAPEGTPVWVNGRRVPIVGRVSM 303 V+ KA + VGYG +TA+ + R+G+VA GY DGYPR+AP GTPV V+G R VG VSM Sbjct: 242 VQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAPTGTPVLVDGVRTMTVGTVSM 301 Query: 304 DMLTVDLGQDAQDKVGDSALLWGKALPVEEVAEHIGTIAYELVTKLTPRV 353 DML VDL Q +G LWGK + +++VA GT+ YEL+ L RV Sbjct: 302 DMLAVDLTPCPQAGIGTPVELWGKEIKIDDVAAAAGTVGYELMCALALRV 351
>MYCMG045#Hypothetical mycoplasma lipoprotein (MG045) signature. Length = 483 Score = 25.8 bits (56), Expect = 0.032 Identities = 22/96 (22%), Positives = 34/96 (35%), Gaps = 17/96 (17%) Query: 14 IELLLSLTRISSPEVIAALTLHYTSALPAERAAARHGIELSNFMRGQKKLEQIA------ 67 + L L+ S + A Y S L ER +H + + +K + A Sbjct: 14 VSLSSILSSCGSTTFVLANFESYISPLLLERVQEKHPLTFLTYPSNEKLINGFANNTYSV 73 Query: 68 ------ATVEAIK-----AIDWAKLQLTHLQSSSLQ 92 A E I+ IDW++ L SSS + Sbjct: 74 AVASTYAVSELIERDLLSPIDWSQFNLKKSSSSSDK 109
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 41.6 bits (97), Expect = 2e-05 Identities = 36/277 (12%), Positives = 79/277 (28%), Gaps = 22/277 (7%) Query: 21 EAKKSEQALQELGRESEKLNEQLDDLKRQ-QEAIKAIDSLTESINKGERAYVDNAQALDK 79 K + EL E E+L + E I L E+A Sbjct: 79 NNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTA 138 Query: 80 LKQEQKQANTEAKNLEKSQQDAAASTAKLETEYSQTAAQLASYDSQLASARAEVERLTTT 139 + K E L + D + + +A++ + +++ A+ A L Sbjct: 139 DSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKA 198 Query: 140 QNKGAQASQAQAKALSAAKTDLQQLESAQKNTATSATKLANELEQERSEFTRLGSEVEKA 199 S A + + + + L + + + + N + ++ L +E Sbjct: 199 LEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAAL 258 Query: 200 GRNKAEYALKVKSARTELNQLGSSLGRNKAELDKQQTVLNKAGID--------------- 244 +AE ++ A + + +AE + Sbjct: 259 EARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDL 318 Query: 245 ------MGKLADASQELKTKQAGAEAALKGVNDKLAQ 275 +L Q+L+ + +EA+ + + L Sbjct: 319 DASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDA 355 Score = 37.4 bits (86), Expect = 5e-04 Identities = 37/216 (17%), Positives = 71/216 (32%), Gaps = 1/216 (0%) Query: 19 SAEAKKSEQALQELGRESEKLNEQLDDLKRQQEAIKA-IDSLTESINKGERAYVDNAQAL 77 SA+ K E L +L + L+ A A I +L D +AL Sbjct: 175 SAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKAL 234 Query: 78 DKLKQEQKQANTEAKNLEKSQQDAAASTAKLETEYSQTAAQLASYDSQLASARAEVERLT 137 + + + K LE + A A+LE + +++ + AE L Sbjct: 235 EGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALE 294 Query: 138 TTQNKGAQASQAQAKALSAAKTDLQQLESAQKNTATSATKLANELEQERSEFTRLGSEVE 197 + SQ + + DL A+K KL + + + L +++ Sbjct: 295 AEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLD 354 Query: 198 KAGRNKAEYALKVKSARTELNQLGSSLGRNKAELDK 233 + K + + + + +S + +LD Sbjct: 355 ASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDA 390 Score = 30.8 bits (69), Expect = 0.041 Identities = 58/347 (16%), Positives = 112/347 (32%), Gaps = 8/347 (2%) Query: 733 EYVTAKQVEDSKLRSKEIQESITRDLDDITNQTKRMKGESSIAYEGLIKTAVKYSGSIDQ 792 + + K + E+ DL+ S + L + Sbjct: 100 KLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKAD 159 Query: 793 LSIAQRNQLNDILLSGKYNGDLEKTYRELTATLVRANRETEIEAEFKNKAADASKKKAEE 852 L A +N LE L A + E F + K E Sbjct: 160 LEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAE 219 Query: 853 DKKAAEAADALAASQGAINDSTKAYAQALKDIEAKQATLNSLYEQGKLSADDLVTASANL 912 A L + + + A + +K +EA++A L + + + + + + S Sbjct: 220 KAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTAD 279 Query: 913 HQTIKAYNVEVDNSNVKAVTQTELTSAFISKRKELQTQYEKGLLTEKELNISLQELA--- 969 IK E + + + R+ L+ + +K+L Q+L Sbjct: 280 SAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQN 339 Query: 970 -ASHTKSVEQSNKSIAATGLLSDAQLDLQEKILRTEKEVRDLEAA-LKDDSKAS-AELTI 1026 S A+ + QL+ + + L + ++ + L+ D AS Sbjct: 340 KISEASRQSLRRDLDASRE--AKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQ 397 Query: 1027 IKAKLAKEEANLADLKRESVELSKIENATYVELLILQRDYEAQLEAL 1073 ++ L + + LA L++ + EL + + T E LQ EA+ +AL Sbjct: 398 VEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKAL 444
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 31.2 bits (71), Expect = 0.006 Identities = 12/62 (19%), Positives = 24/62 (38%) Query: 147 GYDTQAYFIGDIESSVANDAGVFTIVSGESVSADATNSNGVTTNSGALGAQLYNTDGSNS 206 G D+ +FI + A +G+ ++ G + A T + T + + D Sbjct: 132 GMDSHIHFICPQQIEEALMSGLTCMLGGGTGPAHGTLATTCTPGPWHIARMIEAADAFPM 191 Query: 207 NI 208 N+ Sbjct: 192 NL 193
>NEISSPPORIN#Neisseria sp. porin signature. Length = 348 Score = 53.8 bits (129), Expect = 3e-10 Identities = 42/200 (21%), Positives = 84/200 (42%), Gaps = 22/200 (11%) Query: 1 MKKTFISASVASVLALASFGALAEGPSFYGRLELALTHTDTAATLQGGTNGINTTNYADE 60 MKK+ I A LA A+A+ + YG ++ + + G + + T Sbjct: 1 MKKSLI----ALTLAALPVAAMAD-VTLYGAIKAGVQTYRSVEHTDGKVSKVET------ 49 Query: 61 NNAGTYLENNFSLLGVKGSEKIADGFEAIYQMEFQVENTSTTGDVFKARNTYLGLKTNAG 120 G+ + + S +G KG E + +G +A++Q+E Q + + T + + +++GLK G Sbjct: 50 ---GSEIADFGSKIGFKGQEDLGNGLKAVWQLE-QGASVAGTNTGWGNKQSFVGLKGGFG 105 Query: 121 TVLIGRNDTVFKQAEGGVDIFGNTNADIDRLISGQTRSADGMW----YYSPKIAGLVTLN 176 T+ G ++ K V+ + + + L + + Y SP+ AG + Sbjct: 106 TIRAGSLNSPLKNTGANVNAWESGKFTGNVLEISGMAQREHRYLSVRYDSPEFAG---FS 162 Query: 177 ATYLFDDNDTTAKTSESLYA 196 + + D + ES + Sbjct: 163 GSVQYAPKDNSGSNGESYHV 182
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 47.1 bits (112), Expect = 4e-08 Identities = 68/366 (18%), Positives = 121/366 (33%), Gaps = 47/366 (12%) Query: 1 MKKTLLTTAIISSLTLYSFTALADGPEFYGHADLAITNSDT----GYATQNQKDGTVLEN 56 MKK+L+ A+ + + A YG + S + G + + GT + + Sbjct: 1 MKKSLI--ALTLAALPVAAMADVT---LYGTIKAGVETSRSVAHNGAQAASVETGTGIVD 55 Query: 57 NFSWLGVKGSEAVSPYFDIIYQMEFGVENFDNSNKTFNARNTFLGIRSAAGTALVGRNDT 116 S +G KG E + I+Q+E + N R +F+G++ G VGR ++ Sbjct: 56 LGSKIGFKGQEDLGNGLKAIWQVEQKASIAGTDSGWGN-RQSFIGLKGGFGKLRVGRLNS 114 Query: 117 VFKSA------EGSFDLFGNTNADIDLLVAGQTRSADGISYYSPKIADLVTLNATYLMSD 170 V K + D G +A + Y SP+ A L + Y ++D Sbjct: 115 VLKDTGDINPWDSKSDYLGVNK------IAEPEARLISVRYDSPEFAGLSG-SVQYALND 167 Query: 171 NYDQVDNNGDEVYSKDHMYALSATLGDKAFKAQNYYVAAAYSDGIDNVEAYRGVAQAKFG 230 N + E Y Y + ++ + + + +R V+ Sbjct: 168 N---AGRHNSESYHAGFNYKNGGFFVQYGGAYKRHHQVQENVNI-EKYQIHRLVSGYDND 223 Query: 231 DVILG--ALYQHSEHVDDKFANLSGDTYFVNAAYLIGDLKLKMMYGKDDSGLGKYVSRYV 288 + Q ++ V++ +++ S AY G++ ++ Y G Sbjct: 224 ALYASVAVQQQDAKLVEENYSHNSQTEVAATLAYRFGNVTPRVSYAH---GFKGSFD-AT 279 Query: 289 GDQNNSGLEQVRDVDLQQFSVGADYRLSTKTMVYGHYTRFDGDLMLADVKQDLNDNVFTV 348 N D Q VGA+Y S +T + V Sbjct: 280 NYNN----------DYDQVVVGAEYDFSKRTSALVSAGWLQEG----KGESKFVSTAGGV 325 Query: 349 GLRVDF 354 GLR F Sbjct: 326 GLRHKF 331
>PF06580#Sensor histidine kinase Length = 349 Score = 34.8 bits (80), Expect = 6e-04 Identities = 11/61 (18%), Positives = 22/61 (36%), Gaps = 4/61 (6%) Query: 406 EISVEPTLNIQTNISLLNQIVSNILSNAFTHAFQGRED-NLIHISATVDEESILISIQNN 464 E + P + +L Q ++ N H I + T D ++ + ++N Sbjct: 243 ENQINPAIMDVQVPPMLVQT---LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENT 299 Query: 465 G 465 G Sbjct: 300 G 300
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 64.1 bits (156), Expect = 3e-13 Identities = 34/181 (18%), Positives = 59/181 (32%), Gaps = 39/181 (21%) Query: 106 NLKDALASLKSINAQFRAKQAQIRQAKLEFSRQQQMLADKASSRADY-----EVADAN-- 158 NL A ++ A+ + R K +L +A ++ + +A Sbjct: 208 NLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNE 267 Query: 159 LTVYQADLEQLEAQKQQAEINV-----------------------------DSARIDLGY 189 L VY++ LEQ+E++ A+ Sbjct: 268 LRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQA 327 Query: 190 TKITAPMDGTVVYSAV-EVGQTVNANQTTPTIVEMAQLDTMTVKAQISEADVVNVHPGQA 248 + I AP+ V V G V +T IV + DT+ V A + D+ ++ GQ Sbjct: 328 SVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIV--PEDDTLEVTALVQNKDIGFINVGQN 385 Query: 249 V 249 Sbjct: 386 A 386 Score = 46.0 bits (109), Expect = 2e-07 Identities = 31/182 (17%), Positives = 68/182 (37%), Gaps = 16/182 (8%) Query: 7 MKKSSKRKLLLALSGLILLGGGAYFMWHKPETAPAYVTEAVRRGDIENSVLANGMLQAS- 65 S+R L+A I+ F+ + + + +E ANG L S Sbjct: 50 ETPVSRRPRLVAY--FIMGFLVIAFIL-------SVLGQ------VEIVATANGKLTHSG 94 Query: 66 KLVSVGAQVSGQILSLPLALGDEVKKGDLIAQIDSLAQQNNLKDALASLKSINAQFRAKQ 125 + + + + + + G+ V+KGD++ ++ +L + + +SL + Q Sbjct: 95 RSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQ 154 Query: 126 AQIRQAKLEFSRQQQMLADKASSRADYEVADANLTVYQADLEQLEAQKQQAEINVDSARI 185 R +L + ++ + E ++ + + QK Q E+N+D R Sbjct: 155 ILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRA 214 Query: 186 DL 187 + Sbjct: 215 ER 216
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 30.2 bits (68), Expect = 0.015 Identities = 28/116 (24%), Positives = 51/116 (43%), Gaps = 10/116 (8%) Query: 3 AILGMISILFFAWLLSVNRKNIPYRTVILALGLQIIFALLVLYVPAGKAVLQSVTAGVSS 62 A L + +L + +++ +P + + L ++F LL +V G AV+ ++ + Sbjct: 136 AALLLTWVLVALTFIDLDKMLLPDQLTLPLLWGGLLFNLLGGFVSLGDAVIGAMAGYLVL 195 Query: 63 VIAY-------GNEGIGFLFGDLA-TGKVGFVFAINVLGIIIFFSALISALYHIGL 110 Y G EG+G +GD +G L I++ S+L+ A IGL Sbjct: 196 WSLYWAFKLLTGKEGMG--YGDFKLLAALGAWLGWQALPIVLLLSSLVGAFMGIGL 249
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 30.4 bits (68), Expect = 0.002 Identities = 20/74 (27%), Positives = 31/74 (41%), Gaps = 5/74 (6%) Query: 33 LTQGLNEFAMQQKQTELARQQATKDRQLAEYQIQQELQQNAAEKSRLAKQNEAARLRKAE 92 LTQ L + + + +R + + A Q E+ RLAK E AR ++AE Sbjct: 90 LTQRLKDIVNEALRHNASRTPSATELAHANNAAMQA----EDERLRLAKAEEKAR-KEAE 144 Query: 93 AWRKYYLVPEDCKN 106 A K + E + Sbjct: 145 AAEKAFQEAEQRRK 158
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 31.8 bits (72), Expect = 0.018 Identities = 13/67 (19%), Positives = 29/67 (43%), Gaps = 5/67 (7%) Query: 354 AGLEPLTIDAQSLFVNVGERTN---VTGSAKFLKLIKDGKFEQALDVAREQVESGAQIID 410 +P+ +++ + +TN VT + + ++ LD+ R QV A I + Sbjct: 298 QAAKPVAALDKNIIIKAHGQTNALIVTAAPDVMNDLER--VIAQLDIRRPQVLVEAIIAE 355 Query: 411 INMDEGM 417 + +G+ Sbjct: 356 VQDADGL 362
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 37.6 bits (87), Expect = 4e-05 Identities = 44/180 (24%), Positives = 68/180 (37%), Gaps = 16/180 (8%) Query: 18 PHSVLADPAKRIIALSPHAVEMLYAIGAGDAIVAATDYADY------PEAAKKIPRIGGY 71 H+ DP RI+AL VE+L A+G VA D +Y P + +G Sbjct: 28 AHAAAIDP-NRIVALEWLPVELLLALGIVPYGVA--DTINYRLWVSEPPLPDSVIDVGLR 84 Query: 72 YGIQMERVMELNPDLIVVWDTGNKA--EDINQL-KALGFNLYGSDPKTLEGVAKELEELG 128 +E + E+ P + VW G E + ++ GFN + + L K L E+ Sbjct: 85 TEPNLELLTEMKPSFM-VWSAGYGPSPEMLARIAPGRGFN-FSDGKQPLAMARKSLTEMA 142 Query: 129 KLTGHVEEASKAAAAYRAELIRLRTDNASKSE-PKVFYQLWSTPLMTV-SKNSWIQQIIS 186 L A A Y + ++ + P + L M V NS Q+I+ Sbjct: 143 DLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILD 202
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 31.8 bits (72), Expect = 7e-04 Identities = 10/24 (41%), Positives = 18/24 (75%), Gaps = 2/24 (8%) Query: 21 QRGFSLIEVLVALVIL--VIGLIG 42 QRGF+L+E++V +VI+ + L+ Sbjct: 7 QRGFTLLEIMVVIVIIGVLASLVV 30
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 52.2 bits (125), Expect = 1e-11 Identities = 20/61 (32%), Positives = 38/61 (62%) Query: 6 KGFTLIEVMITVVIIGILAAIAYPSYTQYIALSARSEGLAALMRIANLQEQYYLDNRVYA 65 +GFTL+E+M+ +VIIG+LA++ P+ + + + ++ ++ + N + Y LDN Y Sbjct: 8 RGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDNHHYP 67 Query: 66 T 66 T Sbjct: 68 T 68
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 35.2 bits (81), Expect = 3e-05 Identities = 12/28 (42%), Positives = 20/28 (71%) Query: 6 KGFTLVELMVTIAVAAILLTIGVPSLTS 33 +GFTL+E+MV I + +L ++ VP+L Sbjct: 8 RGFTLLEIMVVIVIIGVLASLVVPNLMG 35
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 32.9 bits (75), Expect = 2e-04 Identities = 14/50 (28%), Positives = 30/50 (60%), Gaps = 3/50 (6%) Query: 5 QKGFSLIELMTTLSISTILFTVGTPSFT---DLSDQIRADSNIRTIQQTL 51 Q+GF+L+E+M + I +L ++ P+ + +D+ +A S+I ++ L Sbjct: 7 QRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENAL 56
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 153 bits (387), Expect = 1e-41 Identities = 99/455 (21%), Positives = 177/455 (38%), Gaps = 93/455 (20%) Query: 1 MKQIRNFSIIAHIDHGKSTLSDRLIQVCGGLTD-REMDA--QVLDSMDLERERGITIKAQ 57 MK I N ++AH+D GK+TL++ L+ G +T+ +D D+ LER+RGITI+ Sbjct: 1 MK-IINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTG 59 Query: 58 SVTLDYKAKDGLVYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCY 117 + + ++N IDTPGH+DF EV RSL+ +GA+L++ A GV+AQT + Sbjct: 60 ITSFQW-----ENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFH 114 Query: 118 TALDMNLDVVPILNKIDLPQADPERVAAEIEDIVGIDAI----------------DAVRC 161 M + + +NKID D V +I++ + + + Sbjct: 115 ALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQ 174 Query: 162 SAKTGVGVDEVLEVIVAKIPPPEGDPNAPLQALIID------------------------ 197 G D++LE ++ + + Sbjct: 175 WDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVI 234 Query: 198 -SWF--------------------DNYLGVVSLVRIKHGSLKKGDKFKVMSTGQNHTADR 236 + F ++ +R+ G L D + ++ Sbjct: 235 TNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSV------RISEKEK 288 Query: 237 VGI---FTPKQTDKTELKTGEVGFVIAGLKEI--HGAPVGDTLTLAKNGA-EKPLPGFKK 290 + I +T + ++ G ++ E + +GDT L + E PLP + Sbjct: 289 IKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLPQRERIENPLPLLQT 348 Query: 291 VKPQVYAGVFPISTDEYENFRDALNKLSLNDASLFFEPESSSALGFGFRIGYLGLLHMEI 350 V P + E DAL ++S +D L + +S++ + +LG + ME+ Sbjct: 349 T-------VEPSKPQQREMLLDALLEISDSDPLLRYYVDSATH---EIILSFLGKVQMEV 398 Query: 351 VQERLEREYNLELITTAPTVVY-EVVMTSGETIYV 384 L+ +Y++E+ PTV+Y E + E Sbjct: 399 TCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIH 433 Score = 34.4 bits (79), Expect = 0.001 Identities = 15/67 (22%), Positives = 28/67 (41%), Gaps = 1/67 (1%) Query: 398 EMREPIVEANILVPKEYLGNVITLCIEKRGTQVNMVYHGNQVAVTYHLPMAEVVMDFFDR 457 E+ EP + I P+EYL T + V+ N+V ++ +P + ++ Sbjct: 534 ELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKNNEVILSGEIPARC-IQEYRSD 592 Query: 458 LKSTSRG 464 L + G Sbjct: 593 LTFFTNG 599
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 75.0 bits (184), Expect = 1e-18 Identities = 29/162 (17%), Positives = 59/162 (36%), Gaps = 6/162 (3%) Query: 31 SDARQRLITAALSLFSHRSYPTVSTREIAREAEVDAALIRYYFGSKAGLFEQMVRETLEP 90 + RQ ++ AL LFS + + S EIA+ A V I ++F K+ LF ++ + Sbjct: 10 QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESN 69 Query: 91 VLTRLREISAAEAPNN---VGEIMQTYYRVMAPNPGLPRLIIRVLQEGDGSEPYRIILSV 147 + E A + + EI+ L+ + + + ++ Sbjct: 70 IGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQA 129 Query: 148 FEQVLTLSRQWLESTL---VNSGLLKEGVDPDLARLSFVSLM 186 + S +E TL + + +L + A + + Sbjct: 130 QRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYI 171
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 54.8 bits (132), Expect = 3e-10 Identities = 32/176 (18%), Positives = 62/176 (35%), Gaps = 17/176 (9%) Query: 86 TVERDRLTLTAPVGELITQVNVVEGQQVKAGEVLLTLDSTSANARLALRQAELEQAKAKL 145 T + ++ ++ V EG+ V+ G+VLL L + A A Q+ L Q A+L Sbjct: 91 THSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQ--ARL 148 Query: 146 SEAVTGARLEDIERAKAVLDGAKASVKEAQRAFERTNRLYATKVLSQADLDTARAARDTS 205 + IE + + F+ + +VL L + T Sbjct: 149 EQTRYQILSRSIEL-----NKLPELKLPDEPYFQNVS---EEEVLRLTSL--IKEQFSTW 198 Query: 206 LAKQAEAEQSLRLLENGTRSEQLEQAKAAVAAASASVAIEQKALADLSLVAARDAV 261 ++ + E +L + + A + +E+ L D S + + A+ Sbjct: 199 QNQKYQKELNLD-----KKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAI 249 Score = 49.1 bits (117), Expect = 2e-08 Identities = 31/232 (13%), Positives = 78/232 (33%), Gaps = 15/232 (6%) Query: 108 VEGQQVKAGEVLLTLDSTSANARLALRQAELEQAKAKLSEAVTGARLEDIERAKAVLDGA 167 V ++V L+ ++ + ++ L++ +A+ + AR+ E V Sbjct: 179 VSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVL--ARINRYENLSRVEKSR 236 Query: 168 KASVKE-AQRAFERTNRLYATK---VLSQADLDTARAARDTSLAKQAEAEQSLRLLENGT 223 + + + + V + +L ++ + ++ A++ +L+ Sbjct: 237 LDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLF 296 Query: 224 RSEQLEQAKAAVAAASASVAIEQKALADLS---LVAARDAVVDTLP-WRVGDRIAAGTQL 279 ++E L++ + K + A V L G + L Sbjct: 297 KNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETL 356 Query: 280 IGLLASEDPY-VRVYLPATWLDRVKAGDKVNIRVDG----REMPIAGTVRNI 326 + ++ +D V + + + G I+V+ R + G V+NI Sbjct: 357 MVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNI 408
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 39.9 bits (93), Expect = 8e-06 Identities = 48/200 (24%), Positives = 91/200 (45%), Gaps = 24/200 (12%) Query: 186 GVILTMTMVMFT----SAAIVREREQGNMEFLITTPVRPLELMLGKI--------VPYVI 233 G++ T M T AA R Q E ++ T +R +++LG++ + Sbjct: 72 GMVATSAMTAATFETIYAAFGRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAG 131 Query: 234 VGFVQVTIILSAG-HLLFDVPIRGGIDSIALAAMLFICASLTLGLVISTIAKTQLQSMQM 292 +G V + + LL+ +P+ IAL + F +LG+V++ +A + + Sbjct: 132 IGVVAAALGYTQWLSLLYALPV------IALTGLAFA----SLGMVVTALAPSYDYFIFY 181 Query: 293 TVFILLPSILLSGFMFPYEAMPIAAQWIAEALPATHFMRMSRAIVLRDAQVMDLQFDALW 352 ++ P + LSG +FP + +PI Q A LP +H + + R I+L V+D+ Sbjct: 182 QTLVITPILFLSGAVFPVDQLPIVFQTAARFLPLSHSIDLIRPIML-GHPVVDVCQHVGA 240 Query: 353 MIGFTCIGLFIASMRFSKRL 372 + + I F+++ +RL Sbjct: 241 LCIYIVIPFFLSTALLRRRL 260
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 25.6 bits (56), Expect = 0.043 Identities = 10/59 (16%), Positives = 21/59 (35%), Gaps = 6/59 (10%) Query: 7 HKSYPQAFKDEAVLMVLEQ-GYSVADAAKSLGVSTSLLYNWKEKHQALQQGITLEESER 64 + + +L L + AA LG++ + L + G+++ S R Sbjct: 429 YDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIREL-----GVSVYRSSR 482
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 69.9 bits (171), Expect = 3e-15 Identities = 99/417 (23%), Positives = 165/417 (39%), Gaps = 52/417 (12%) Query: 1 MNKTLVATALAAMFLVPSVSAIEIYKDNKNAVEIGGFIDARVINTQGETEVVNG-ASRIN 59 M + ++A + A+ + A EIY + N +++ G +D + ++ +G + + Sbjct: 1 MKRKVLALVIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSDDSSK--DGDQTYMR 58 Query: 60 FGFNRE--LTDGWKAFAKLEWGVNPVGNSDIVYNNRFESVQEEFFYNRLGYAGLSHDTYG 117 GF E + D + + E+ V N E + RL +AGL YG Sbjct: 59 VGFKGETQINDQLTGYGQWEYNVQ---------ANTTEGEGANSW-TRLAFAGLKFGDYG 108 Query: 118 TLTIGKQWGAWYDVVYNTNYGFVWDGNTAGVYTYNKDDGAVNGVGRGDKTVQYRNA--FG 175 + G+ +G YDV T+ + G++ Y N G NGV YRN FG Sbjct: 109 SFDYGRNYGVLYDVEGWTDMLPEFGGDSYT-YADNYMTGRANGV------ATYRNTDFFG 161 Query: 176 DV---SFAVQAQLKNS--SFYTCDTTDDITQAQCQANWESGDKAAQQVEYNYTYGGALTY 230 V +FA+Q Q KN S + + +++GD Y+ G + Sbjct: 162 LVDGLNFALQYQGKNESQSADDVNIGTNNRNNGDDIRYDNGDGFGISTTYDIGMGFSAGA 221 Query: 231 KVTDMLTLTAGVNRGEFDVSFGNGEQTTAVDLIYGAGITWGNFDNDGLYAAA------NV 284 T VN G + G++ A + AG+ +D + +Y A N+ Sbjct: 222 AYTTSDRTNEQVNAG---GTIAGGDKADA----WTAGL---KYDANNIYLATMYSETRNM 271 Query: 285 NRQENHDTDNIGRLIKDAYGIESLVSYKFDNGLRPFISYNVLDAGKDYVIQPNFNADPND 344 D G + E Y+FD GLRP +S+ ++ GKD + N N D D Sbjct: 272 TPYGKTDKGYDGGVANKTQNFEVTAQYQFDFGLRPAVSF-LMSKGKD-LTYNNVNGDDKD 329 Query: 345 EFKRQFLVVGLHFVWDPNTVLYIEARKDYSDFTSADKDQEARMALSESDGVAIGIRY 401 K + VG + ++ N Y++ + + D D +S D VA+G+ Y Sbjct: 330 LVK--YADVGATYYFNKNFSTYVDYKINLLD---DDDPFYKDAGISTDDIVALGMVY 381
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 101 bits (253), Expect = 1e-28 Identities = 34/169 (20%), Positives = 64/169 (37%), Gaps = 11/169 (6%) Query: 39 TPVIEITMDRQDSKAQNKPRVVPKPPPPPEQPQKPDTTPPDSSSNID----TAMSFNMGG 94 P E + K PKP P P+ P + N Sbjct: 75 EPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAP 134 Query: 95 VEAGGASTG-FKLGNMMTRDGDATPIVRIEPQYPIAAARDGKEGWVQLRFTINELGGIDD 153 ++ + + + R +PQYP A EG V+++F + G +D+ Sbjct: 135 ARPTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDN 194 Query: 154 VEVIQAEPKRLFDKEAIRALKKWKYKPKIVDGKPLKQPGQTVQLDFTLD 202 V+++ A+P +F++E A+++W+Y+P G V + F ++ Sbjct: 195 VQILSAKPANMFEREVKNAMRRWRYEP------GKPGSGIVVNILFKIN 237
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 29.1 bits (65), Expect = 0.021 Identities = 11/51 (21%), Positives = 21/51 (41%) Query: 197 YFNQKKYKKAVGVLEVMVPLFPDDGRLWVQLAQFYLMVEDYDKSLATYDLA 247 + KY+ A V + + L D R ++ L + YD ++ +Y Sbjct: 46 QYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYG 96
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 49.3 bits (117), Expect = 8e-08 Identities = 48/306 (15%), Positives = 104/306 (33%), Gaps = 14/306 (4%) Query: 198 AADISALVKDQRSRRDGILQSAGLASDDELSNELAKLTPELALA--QSAKEQALQQQQLI 255 +I A V S + I + ++ T +A Q +K +Q Sbjct: 1000 PNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDAT 1059 Query: 256 IKASDAAQHLLAEFAQFDTLTQTAAALEAQQESIVAQTHKLNLAEQAQRLAPMIEVFLAR 315 + + + TQT ++ E+ QT + ++ + + + Sbjct: 1060 ETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTE---TKETATVEKEEKAKVET 1116 Query: 316 EQEAKAANLAFSHAQTALTQAKQAFDDAELKAQDLPVLEASLLEQEQAKQQLNALGPQL- 374 E+ + + S Q++ AE ++ P + ++ Q++ A Q Sbjct: 1117 EKTQEVPKVT-SQVSPKQEQSETVQPQAEPARENDPTVNI---KEPQSQTNTTADTEQPA 1172 Query: 375 RELDRLNKTLEQEQAQLVKAKTQLQISKNELTAASQKRRELESALPQLQANSDTRLTLQQ 434 +E + E + + ++ +N A +Q ES+ N R Sbjct: 1173 KETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESS--NKPKNRHRRSVRSV 1230 Query: 435 AHQQQQQLLSTYQQWQQVAARVSS--TKAKLANAKAQGQQLNAEHQQAQVAHKALLITWH 492 H + S+ + ++S T A L++A+A+ Q + +A H + L + Sbjct: 1231 PHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHISQLEMNN 1290 Query: 493 QGQAAI 498 +GQ + Sbjct: 1291 EGQYNV 1296 Score = 43.9 bits (103), Expect = 4e-06 Identities = 49/325 (15%), Positives = 95/325 (29%), Gaps = 32/325 (9%) Query: 277 QTAAALEAQQESIVAQTHKLNLAEQAQRLAPMIEVFLAREQEAKAANLAFSHAQTALTQA 336 + E+ V +E + +A +QE+K A Q Sbjct: 1012 SNNEEIARVDEAPVPPPAPATPSETTETVA------ENSKQESKTVEKNEQDATETTAQN 1065 Query: 337 KQAFDDAELKAQDLPVLEASLLEQEQAKQQLNALGPQLRELDRLNKTLEQEQAQLVKAKT 396 ++ +A+ ++A+ E A+ Q E ++E+A++ KT Sbjct: 1066 REVAKEAK------SNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKT 1119 Query: 397 QLQISKNELTAASQKRRELESALPQLQANSDTRLTLQQAHQQQQQLLSTYQQWQQVAARV 456 Q + Q++ E + +D + +++ Q T +Q A Sbjct: 1120 QEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADT----EQPAKET 1175 Query: 457 SSTKAKLANAKAQGQQLNAEHQQAQVAHKALLITWHQGQAAILARQLQQDEPCPVCGSQI 516 SS + N+ + + A ++P + Sbjct: 1176 SSNVEQPVTESTTVNTGNSVVENPENTTPA--------TTQPTVNSESSNKPKNRHRRSV 1227 Query: 517 HPQPAQSQEPL---PSDEALQLAQDAETTAQEVLSKARA--EYRGLQTQLETLQQQAQ-- 569 P + + L T VLS ARA ++ L Q +Q Sbjct: 1228 RSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHISQLE 1287 Query: 570 -DLAAQLGTAVDISQDQHAHTLSQY 593 + Q V + ++ SQY Sbjct: 1288 MNNEGQYNVWVSNTSMNKNYSSSQY 1312
>PF05043#Transcriptional activator Length = 493 Score = 28.4 bits (63), Expect = 0.035 Identities = 17/64 (26%), Positives = 30/64 (46%), Gaps = 3/64 (4%) Query: 2 NKLDRLDIKQLRVFQALIREQSA---SKAASQLGLTQQAVSEQLKKLRDVFEDRLFLRKT 58 + L + +QL + + L + S+ A L T++AV + L ++ F D +F T Sbjct: 3 DLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKDDLSHVKSAFPDLIFHSST 62 Query: 59 NGFV 62 NG Sbjct: 63 NGIR 66
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 41.2 bits (96), Expect = 1e-06 Identities = 29/124 (23%), Positives = 49/124 (39%), Gaps = 7/124 (5%) Query: 39 VDITDENSIRA----LYEKVGHFDAVVNTVGFCEYATFADMTESQWMATVMSKMMGQISL 94 D+ D +I + ++G D +VN G +++ +W AT G + Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 95 VRIGQDYIAD--NGSFTLISGILNVKPIPYAIADATTSGAIDTFVKCVAHEM-PRGTRIN 151 R Y+ D +GS + P A A++ A F KC+ E+ R N Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 152 VVNP 155 +V+P Sbjct: 184 IVSP 187
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 25.9 bits (57), Expect = 0.027 Identities = 10/59 (16%), Positives = 21/59 (35%), Gaps = 6/59 (10%) Query: 7 HKSYPQAFKDEAVLMVLEQ-GHSVADAAKSLGVSTSLLYNWKEKHQALQQGITLEESER 64 + + +L L + AA LG++ + L + G+++ S R Sbjct: 429 YDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIREL-----GVSVYRSSR 482
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 53.1 bits (127), Expect = 6e-09 Identities = 38/293 (12%), Positives = 83/293 (28%), Gaps = 12/293 (4%) Query: 540 PALKGFAAPQKVEQAPSPTVKVEAPQPGFFSKLVSAVSAMFAPSEKAEPVKVVETKTADT 599 P ++ +P ++A P S + A + P ++T +T Sbjct: 983 PEVEKRNQTVDTTNITTPN-NIQADVPSVPSN--NEEIARVDEAPVPPPAPATPSETTET 1039 Query: 600 SAANANRRNRRNDTRRPRNAQDADKAKEGTREPRSRNPKKPADAAVSTSTQERPVREKEE 659 A N+ + ++ + + + +E +E +S V+ S E +E Sbjct: 1040 VAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSE-----TKE 1094 Query: 660 AVKRPAKAEPKPRVQAPKDVVADVEADAPKQEVARERRQRRNMRRKVRIDNGHNTPDNAI 719 K + V + + PK V + ++ V+ ++ Sbjct: 1095 TQTTETKETATVEKEEKAKVETEKTQEVPK--VTSQVSPKQEQSETVQPQAEPARENDPT 1152 Query: 720 LIAPEDAAEVLAEIAAINAAAASTISVDTKAEVAQAPAETKAPRTRRQPRKEAAPALEAA 779 + E ++ A A S + + V ++ P + Sbjct: 1153 VNIKEPQSQTNTT--ADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPT 1210 Query: 780 ENIAVEEKAMSSAAAETPAVDAVKTEEQAEVVTTEVAAPADAVSQDNDAVDAE 832 N K + +V A D S + +AV ++ Sbjct: 1211 VNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSD 1263 Score = 50.4 bits (120), Expect = 4e-08 Identities = 43/273 (15%), Positives = 89/273 (32%), Gaps = 33/273 (12%) Query: 714 TPDNAILIAPEDAAEVLAEIAAINAAAASTISVDTKAEVAQAPAETKAPRTRRQPRKEAA 773 T N I EIA ++ A + T +E + AE ++ + E Sbjct: 998 TTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQD 1057 Query: 774 PALEAAENIAVEEKAMSSAAAETPAVDAVKTEEQAEVVTTEVAAPADAVSQDNDAVDAES 833 A+N V ++A S+ A T + ++ + + T Sbjct: 1058 ATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTET----------------K 1101 Query: 834 ETADDQAKREQRDGQRRSRRSPRHLRAAGQRRRRDEDDQGTSTPA----------QFVPN 883 ETA + + + + +++ P+ ++ + E Q + PA + Sbjct: 1102 ETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQ 1161 Query: 884 DELGADQEYPSEVASVRVEAPVVATKTDAVTETQVTAKSVEVETAQASEAPAVEASAVVK 943 AD E P++ S VE PV + T + VE + + + + + Sbjct: 1162 TNTTADTEQPAKETSSNVEQPVTESTTVNTGNS-------VVENPENTTPATTQPTVNSE 1214 Query: 944 AATKVETPANDVIAAETKPVEAKSVETKATEAE 976 ++ K + + + VE + + Sbjct: 1215 SSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTV 1247
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 40.7 bits (95), Expect = 5e-07 Identities = 20/57 (35%), Positives = 30/57 (52%) Query: 80 LILNDVYVTQHARCVGIGRALVQQAASYAKAHNMSYLMLETQQKNQRAQGLYEGLGF 136 ++ D+ V + R G+G AL+ +A +AK ++ LMLETQ N A Y F Sbjct: 90 ALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 76.3 bits (187), Expect = 4e-16 Identities = 34/128 (26%), Positives = 60/128 (46%), Gaps = 9/128 (7%) Query: 784 APVASFTQVVNGAAVQLTST-STDSDGQIVSAEWSFGDNTVAVGEVVTHSYSQSGEYLVT 842 A + S + V+ + T S D DG+I + EW FGD + TH Y+++GEY V Sbjct: 777 AVIKSDSSVIVEEEINFDGTESKDEDGEIKAYEWDFGDGEKSNEAKATHKYNKTGEYEVK 836 Query: 843 LTVTDNDGLTHSTSQTVTVVVGEVKQP------PVAQIQRINLLF-VDMFISTSYDTDGV 895 LTVTDN+G ++ S+ + VV + P ++ N + +M + + + Sbjct: 837 LTVTDNNGGINTESKKI-KVVEDKPVEVINESEPNNDFEKANQIAKSNMLVKGTLSEEDY 895 Query: 896 IKQHKWTF 903 ++ + Sbjct: 896 SDKYYFDV 903 Score = 40.5 bits (94), Expect = 4e-05 Identities = 18/55 (32%), Positives = 31/55 (56%), Gaps = 1/55 (1%) Query: 889 SYDTDGVIKQHKWTFDNGTRAN-GQVVLRLARRGQHTVELTVKDNDKLTGTTTLT 942 S D DG IK ++W F +G ++N + + + G++ V+LTV DN+ T + Sbjct: 798 SKDEDGEIKAYEWDFGDGEKSNEAKATHKYNKTGEYEVKLTVTDNNGGINTESKK 852
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 38.8 bits (90), Expect = 1e-05 Identities = 31/202 (15%), Positives = 66/202 (32%), Gaps = 47/202 (23%) Query: 48 GVLINSQWILTVAHTIFYDYVGKSLMVGSKNYEIESVHIHPDYSEPDKSLLKGDLAPLMR 107 GV++ +LT H + + ++ P D G A + Sbjct: 106 GVVVGKDTLLTNKHVVDATHGDPH-----------ALKAFPSAINQDNYPNGGFTAEQIT 154 Query: 108 FFKSRSDIALIKLT------SPVSGIEPINI-YTGKSEEGKKITVYGKGATGNGVTGEYP 160 + D+A++K + ++P + +++ + ITV G YP Sbjct: 155 KYSGEGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTG-----------YP 203 Query: 161 DTKSLRVMSHFQNVIESAEGNWLAFKFDEPANALSLEGMHGSGDSGGASVIFEDSIPFLV 220 K + M + I +G + + G+SG S +F + ++ Sbjct: 204 GDKPVATMWESKGKITYLKGEAMQYDLSTT-----------GGNSG--SPVFNEKNE-VI 249 Query: 221 GLSSWQLGHGDISTFKGGLYGT 242 G+ + + F G ++ Sbjct: 250 GIHWGGVPN----EFNGAVFIN 267
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 31.3 bits (71), Expect = 0.010 Identities = 16/36 (44%), Positives = 23/36 (63%) Query: 158 NLVIDIGGGSTEVVIGKKNTPTQLSSLRCGCVSFNE 193 ++V+DIGGG+TEV + N SS+R G F+E Sbjct: 161 SMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDE 196
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 41.3 bits (97), Expect = 6e-06 Identities = 24/81 (29%), Positives = 42/81 (51%), Gaps = 11/81 (13%) Query: 192 AAKRAGFVDVDFLFEPLAAGMDYEASLTDNKTVLVVDVGGGTTDCSVVKMGPAHQQKADR 251 +A+ AG +V + EP+AA + +++ +VVD+GGGTT+ +V+ + Sbjct: 129 SAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLN--------- 179 Query: 252 SEDFLGHSGQRIGGNDLDIAL 272 + S RIGG+ D A+ Sbjct: 180 --GVVYSSSVRIGGDRFDEAI 198
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 38.6 bits (90), Expect = 8e-05 Identities = 13/27 (48%), Positives = 21/27 (77%) Query: 655 TLHPAMQHNIGDKLGSLEKGKLADMVV 681 T++PA+ H + ++GSLE GK AD+V+ Sbjct: 410 TINPAIAHGLSHEIGSLEVGKRADLVL 436
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 29.0 bits (65), Expect = 0.025 Identities = 11/35 (31%), Positives = 16/35 (45%) Query: 6 ESVFTTWSQGPSKTEQERAENAERQIRQAIHASEK 40 + VF T Q P+ QER + Q+ +EK Sbjct: 568 QGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNEK 602
>SALSPVBPROT#Salmonella virulence plasmid 65kDa B protein signature. Length = 591 Score = 42.4 bits (99), Expect = 2e-05 Identities = 44/178 (24%), Positives = 70/178 (39%), Gaps = 16/178 (8%) Query: 296 GQASYQIPIDLPPGRNGVQPSVSLSYNSQGGNGILGVGWSLNAGSSISRCGATFAQ---- 351 G AS +P+ + R G P+++L Y+S GGNG GVGWS S Q Sbjct: 34 GLASITLPLPISAER-GFAPALALHYSSGGGNGPFGVGWSCATMSIARSTSHGVPQYNDS 92 Query: 352 ------DGFTRAVTFSA--STDRLCLDGQRLIATTGSYGASNAEYRTEMDSFVKVVQQGN 403 DG T S + + + ++ SY + + RTE F ++ Sbjct: 93 DEFLGPDGEVLVQTLSTGDAPNPVTCFAYGDVSFPQSYTVTRYQPRTESS-FYRLEYWVG 151 Query: 404 INDSNSRFTVYKPDGNSATYGANANSRFV-PSGLSTALSWKVTQESYSDGANTIDYKY 460 ++ + + ++ +G G A +R P S W V +ES + I Y Y Sbjct: 152 NSNGDDFWLLHDSNGILHLLGKTAAARLSDPQAASHTAQWLV-EESVTPAGEHIYYSY 208
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.3 bits (71), Expect = 0.002 Identities = 10/47 (21%), Positives = 21/47 (44%), Gaps = 1/47 (2%) Query: 7 EKVVELEGIENAIVRSAAELC-YIQPQGPALVIIDIKLPNAAVLEWV 52 + + G + I +AA L +I LV+ D+ +P+ + + Sbjct: 20 NQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDLL 66
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 44.3 bits (104), Expect = 3e-06 Identities = 47/370 (12%), Positives = 110/370 (29%), Gaps = 3/370 (0%) Query: 830 TGAAVPETLKAQAATLGLTKELSDLTAKQYGYTDSVKELSPEQAKLSRAVAETEARLKQC 889 G V + AT T L + + + L + + LS + + Sbjct: 31 AGLVVNTNEVSAVATRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDEL 90 Query: 890 RDVMNSSTVSSKAKAKAQQDLISLQGKLSDQTKQLSEVQALEAANYEQIKSKYAAVSDEM 949 + ++++ + K+ + S +L + L + +K + E Sbjct: 91 TEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEK 150 Query: 950 LRLEQAYKDGGITAEEYLRQKERLVEVLRILQRLMGGLEEGEQETDEQVKKTTKTLIEQR 1009 L D E + ++ L+ LE + E ++ ++ Sbjct: 151 AALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADS 210 Query: 1010 EELEQLEETTGRATEYVNLFAGAYAHLNKQFNFNEDSTEKLNARVDQLTNSIMNNMRVNT 1069 +++ LE A + + L A L + Sbjct: 211 AKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALE 270 Query: 1070 GFWGVLAQLSNQAFIREKQIINETLLTRKWTEELESSSISLDRVNQISREAKWNIRELGD 1129 G S + E + + + + + + + ++ ++L Sbjct: 271 GAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEA 330 Query: 1130 EDLKPLQAAIDATRDRILGLRDDINATLGSLKDEMDQLNNNQAAIEKRRYEQQQAELKAQ 1189 E K L+ + LR D++A+ + K + + + + E + L+ Sbjct: 331 EHQK-LEEQNKISEASRQSLRRDLDASREAKKQLEAEHQ--KLEEQNKISEASRQSLRRD 387 Query: 1190 LDAARTAQDK 1199 LDA+R A+ + Sbjct: 388 LDASREAKKQ 397 Score = 37.0 bits (85), Expect = 6e-04 Identities = 41/276 (14%), Positives = 84/276 (30%) Query: 749 LTILRAKFEEQQTYLDATAKGAEALEQAYKDLGLTSSHALEQVNTKAEAAFNLIKNNREP 808 I + + + L K + + + L + + + I+ Sbjct: 62 FEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEAR 121 Query: 809 IEQQKDAFLAWAKAALTAAEATGAAVPETLKAQAATLGLTKELSDLTAKQYGYTDSVKEL 868 + A + + E A L K L + +K L Sbjct: 122 KADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTL 181 Query: 869 SPEQAKLSRAVAETEARLKQCRDVMNSSTVSSKAKAKAQQDLISLQGKLSDQTKQLSEVQ 928 E+A L AE E L+ + + + K + L + + L + Sbjct: 182 EAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFS 241 Query: 929 ALEAANYEQIKSKYAAVSDEMLRLEQAYKDGGITAEEYLRQKERLVEVLRILQRLMGGLE 988 ++A + ++++ AA+ LE+A + + + + L L+ LE Sbjct: 242 TADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLE 301 Query: 989 EGEQETDEQVKKTTKTLIEQREELEQLEETTGRATE 1024 Q + + + L RE +QLE + E Sbjct: 302 HQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEE 337
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 45.6 bits (108), Expect = 3e-07 Identities = 19/90 (21%), Positives = 33/90 (36%), Gaps = 9/90 (10%) Query: 28 KVLVVDDEPDVHTVTKLALSRFKLDGRPLTFINAYSAEQAKELMNQEHDIAIAFIDVVME 87 +LV DD+ + TV ALSR +A + + DVVM Sbjct: 5 TILVADDDAAIRTVLNQALSR-----AGYDVRITSNAATLWRWIAAGD-GDLVVTDVVMP 58 Query: 88 SDHAGLELVKWIREELQNKTTRLILRTGQP 117 D +L+ I++ +++ + Q Sbjct: 59 -DENAFDLLPRIKKA--RPDLPVLVMSAQN 85
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 30.2 bits (68), Expect = 0.016 Identities = 11/33 (33%), Positives = 15/33 (45%), Gaps = 8/33 (24%) Query: 53 QCPCCQHPLTWQQH--LFSH------CLHCKQP 77 CP C HP+T ++ L S C C+ P Sbjct: 73 CCPHCNHPITALENIPLLSWLWLRGRCRGCQAP 105
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 63.3 bits (154), Expect = 6e-14 Identities = 21/102 (20%), Positives = 43/102 (42%), Gaps = 4/102 (3%) Query: 11 ILVVDDHSLIFDGLRGCLAPYPELNL-IGSVEDGLAVYEKCLKLRPDLVFMDLKLPGMGG 69 ILV DD + I L L+ + DLV D+ +P Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAA---GDGDLVVTDVVMPDENA 62 Query: 70 LDVIRQLRQRWPEMMIIMLTGTIEEKSAREALDVGANGYVLK 111 D++ ++++ P++ +++++ +A +A + GA Y+ K Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPK 104
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 74.1 bits (182), Expect = 1e-15 Identities = 27/120 (22%), Positives = 46/120 (38%), Gaps = 8/120 (6%) Query: 696 KILLVDDVETNRDIISKMLLELGQQVIAVSSGEAALEKGTRHIFDLVLMDIRMPGLDGYQ 755 IL+ DD R ++++ L G V S+ DLV+ D+ MP + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 756 TTQQWRHSENILDGDCPIFALTANANPKEHDTIEA--AGMNSYITKPVSLKQLNHALEAA 813 + + D P+ ++A I+A G Y+ KP L +L + A Sbjct: 65 LLPRIKK----ARPDLPVLVMSAQNTF--MTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 440 bits (1133), Expect = e-152 Identities = 156/503 (31%), Positives = 262/503 (52%), Gaps = 24/503 (4%) Query: 6 SLLLLCQMGLAQAAPLTNIKWQGEPFVMISRGTALTSVIQDFASNYGVPVIVSNKVNDNY 65 +LLLL AQ W P+V +++G +L ++ DF +NY V+VS+K+ND Sbjct: 16 TLLLLSSYSWAQELD-----WLPIPYVYVAKGESLRDLLTDFGANYDATVVVSDKINDKV 70 Query: 66 IGQIQEQDPKSVIQDLTRRYGLVWYYNNEVLYVYKASEINSEVLPLTSLSATKVDHYLRS 125 GQ + +P+ +Q + Y LVWYY+ VLY++K SE+ S ++ L A ++ L+ Sbjct: 71 SGQFEHDNPQDFLQHIASLYNLVWYYDGNVLYIFKNSEVASRLIRLQESEAAELKQALQR 130 Query: 126 AGVLDKGVCNIKSMAGISGLQVTGVPECINSVTKLTAQLDANAKQTTE--NQETVKVYPL 183 +G+ + + A + V+G P + V + A L+ + +E ++++PL Sbjct: 131 SGIWEPR-FGWRPDASNRLVYVSGPPRYLELVEQTAAALEQQTQIRSEKTGALAIEIFPL 189 Query: 184 KYASATDSIYEYRSQPVSIPGLVTVLKEMDQGTQV-------ANAVAGSVSNISGPVFAA 236 KYASA+D YR V+ PG+ T+L+ + + + + A Sbjct: 190 KYASASDRTIHYRDDEVAAPGVATILQRVLSDATIQQVTVDNQRIPQAATRASAQARVEA 249 Query: 237 DPRQNAIIVRGSARDMATYGSLIRQLDTKPSMIEVSVSIFDVDASDFKQLGIDWSASAKL 296 DP NAIIVR S M Y LI LD + IEV++SI D++A +LG+DW + Sbjct: 250 DPSLNAIIVRDSPERMPMYQRLIHALDKPSARIEVALSIVDINADQLTELGVDWRVGIRT 309 Query: 297 GGGSVSFN---------SGDSSDNFSTVIGNTGNFMMRLNALEKNSKAKVLSRPSVVTLN 347 G + + + + R+N LE A+V+SRP+++T Sbjct: 310 GNNHQVVIKTTGDQSNIASNGALGSLVDARGLDYLLARVNLLENEGSAQVVSRPTLLTQE 369 Query: 348 NVQAVLDKNVTFYTKLEGDKVAKLESVTTGSLLRVTPRLIDEVGHQAVMLDLNIQDGQQS 407 N QAV+D + T+Y K+ G +VA+L+ +T G++LR+TPR++ + + L+L+I+DG Q Sbjct: 370 NAQAVIDHSETYYVKVTGKEVAELKGITYGTMLRMTPRVLTQGDKSEISLNLHIEDGNQK 429 Query: 408 QAVSRSEPLPQVQNSEISTQATLKSGESLLLGGFVQDRDETTQNKIPLLGDLPLLGGLFR 467 S E +P + + + T A + G+SL++GG +D +K+PLLGD+P +G LFR Sbjct: 430 PNSSGIEGIPTISRTVVDTVARVGHGQSLIIGGIYRDELSVALSKVPLLGDIPYIGALFR 489 Query: 468 STDHHTQSVMRLFLIKAEPVNQG 490 T+ +RLF+I+ +++G Sbjct: 490 RKSELTRRTVRLFIIEPRIIDEG 512
>CLENTEROTOXN#Clostridium enterotoxin signature. Length = 319 Score = 29.2 bits (65), Expect = 0.036 Identities = 22/132 (16%), Positives = 40/132 (30%), Gaps = 18/132 (13%) Query: 246 SSEDNSLRYAVTPSRYELLNCVAAHGMEDEGLARVLYQAKVGNTNLGALYGLPAPKDAPQ 305 +E + T +Y+ + ++ + D+G L + T A Sbjct: 124 PNEYVYYKVYATYRKYQAIR-ISHGNISDDGSIYKLTGIWLSKT------------SADS 170 Query: 306 LDNVDD--FILCDEDINLGVSQTDVYADEETFYQGIGQHQTTTTGDN--CYKLLQLNIND 361 L N+D I E L V TD+ + + T ++ L + Sbjct: 171 LGNIDQGSLIETGERCVLTVPSTDIEKEILDLAAATERLNLTDALNSNPAGNLYDWR-SS 229 Query: 362 GLHYLATKANPH 373 + K N H Sbjct: 230 NSYPWTQKLNLH 241
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 93.1 bits (231), Expect = 7e-27 Identities = 43/148 (29%), Positives = 68/148 (45%) Query: 9 DFEKLEAACQLALVNQQTLAEQVGLTSQDLELIYQSGTSKYQMGLPAEAIVDFTYLVMHQ 68 D ++ + A + L T+A ++S LE +Y ++YQ G +A F L + Sbjct: 7 DTQEYQLAMESFLKGGGTIAMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLD 66 Query: 69 PWDRRFHLGLGSCLHWLGEYQHALTFYGYALLMDACSPEASFRIAQCFLSLNDDAAAIEA 128 +D RF LGLG+C +G+Y A+ Y Y +MD P F A+C L + A A Sbjct: 67 HYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESG 126 Query: 129 LQMAISQSYSKPEHHFVGDQAQQLLSAL 156 L +A K E + + +L A+ Sbjct: 127 LFLAQELIADKTEFKELSTRVSSMLEAI 154
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 37.5 bits (87), Expect = 6e-05 Identities = 8/114 (7%), Positives = 38/114 (33%), Gaps = 1/114 (0%) Query: 259 YQLRQLQASALTQQGNMKLSEAQL-ALKESQANEKTAQFDAEIRMKQSERFRGTNQTLQQ 317 + Q+S L + + +++ ++ E + + E +++ Sbjct: 134 ADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKE 193 Query: 318 QLAEKEGLLLQSQNQFEQLQSRFDKSNVQLSGVMQQLQMLQQQLAELQPARARN 371 Q + + Q + ++ ++ +++ ++ + +L + + Sbjct: 194 QFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQ 247 Score = 29.0 bits (65), Expect = 0.037 Identities = 18/129 (13%), Positives = 49/129 (37%), Gaps = 13/129 (10%) Query: 244 SQNKSFEAEVSSVKAYQLRQLQASALTQQGNMKLSEAQLALKESQANEKTAQFDAEIRMK 303 Q +++ + + L + +A LT + E +++S+ ++ ++ Sbjct: 193 EQFSTWQNQKYQKEL-NLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLH------ 245 Query: 304 QSERFRGTNQTL--QQQLAEKEGLLLQSQNQFEQLQSRFDKSNVQLSGVMQQLQMLQQQL 361 ++ + L + + E L ++Q EQ++S + + V Q + + L Sbjct: 246 --KQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFK--NEIL 301 Query: 362 AELQPARAR 370 +L+ Sbjct: 302 DKLRQTTDN 310
>PF06340#Vibrio cholerae toxin co-regulated pilus biosynthesis protein F (TcpF) Length = 338 Score = 28.8 bits (64), Expect = 0.007 Identities = 7/39 (17%), Positives = 19/39 (48%) Query: 27 EMRRLFNRYFCGQQEDDNAISTKDRLTAKALLSRDGGVY 65 +++L+ ++ Q D I T+D++ + +G + Sbjct: 110 SLQKLYIDFYLAQTTFDWEIPTRDQIETLVNYANEGKLS 148
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 27.9 bits (62), Expect = 0.047 Identities = 9/44 (20%), Positives = 19/44 (43%) Query: 224 SLLPKMDAIQPPLTADIGRVSLPLAKLGAMMTGDKLTLEVTLNN 267 L K+ + + A++G + L + + + GD + L T Sbjct: 249 VLRDKLSTVDMDVVAEVGSLRLSVRDILGLRVGDIIRLHDTHVG 292
>TYPE3IMPPROT#Type III secretion system inner membrane P protein family signature. Length = 224 Score = 210 bits (537), Expect = 3e-71 Identities = 81/215 (37%), Positives = 129/215 (60%), Gaps = 7/215 (3%) Query: 8 IQLIIMLFCLSLLPLFAVMGTSFLKLAIVFSMLRNALGIQQIPPNMAIYGLALILTLFTM 67 I LI +L +LLP GT F+K +IVF M+RNALG+QQIP NM + G+AL+L++F M Sbjct: 5 ISLIALLAFSTLLPFIIASGTCFVKFSIVFVMVRNALGLQQIPSNMTLNGVALLLSMFVM 64 Query: 68 APVGMAINDNLKATPIVFDAPNVFEQINTEAIAPYRAFLEKNTSNTQIEFFANIGHKVWP 127 P+ + + F+ + + E + YR +L K + ++FF N K Sbjct: 65 WPIMHDAYVYFEDEDVTFNDISSLSKHVDEGLDGYRDYLIKYSDRELVQFFENAQLKRQY 124 Query: 128 EKYQQV-------LTKDSLLVMVPAFTMSQLIEAFKIGLLIYLPFVAIDLIVSNILLAMG 180 + + + K S+ ++PA+ +S++ AFKIG +YLPFV +DL+VS++LLA+G Sbjct: 125 GEETETVKRDKDEIEKPSIFALLPAYALSEIKSAFKIGFYLYLPFVVVDLVVSSVLLALG 184 Query: 181 MMMVSPMTIALPFKLLIFILMGGWEKLISQLMMSF 215 MMM+SP+TI+ P KL++F+ + GW L L++ + Sbjct: 185 MMMMSPVTISTPIKLVLFVALDGWTLLSKGLILQY 219
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 70.2 bits (172), Expect = 7e-20 Identities = 33/83 (39%), Positives = 50/83 (60%) Query: 6 IVHFTSELLWMVLLLSLPVVIVASVVGVLVSLIQALTQIQDQTLQFLIKLIAVCVTLVVC 65 +V ++ L++VL+LS IVA+++G+LV L Q +TQ+Q+QTL F IKL+ VC+ L + Sbjct: 4 LVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLFLL 63 Query: 66 YHWMGSSLLNYASMAFDQISQMG 88 W G LL+Y G Sbjct: 64 SGWYGEVLLSYGRQVIFLALAKG 86
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 126 bits (319), Expect = 2e-37 Identities = 47/238 (19%), Positives = 104/238 (43%), Gaps = 5/238 (2%) Query: 1 MTTQLPNLLTAQLPVLALCMMRPLGMMLLLPLFKGGAMGSALIRNSLILMFALPTVLAMD 60 M + L + ++R L ++ P+ ++ ++ L +M + Sbjct: 1 MLQVTSEQWLSWLNLYFWPLLRVLALISTAPILSERSVPK-RVKLGLAMMITFA-IAPSL 58 Query: 61 EMQPILQQADTWMLISLFGKEIIVGMLLGFCAAIPFWAIDMAGFVIDTMRGASMSTVLNP 120 + + + +++ ++I++G+ LGF F A+ AG +I G S +T ++P Sbjct: 59 PANDVPVFSFFALWLAV--QQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDP 116 Query: 121 LMGLQSSIYGMLFTQVLTVLFLVSGGFNFLLTALYQSYQQLPPGFNLTLSQPLMVFIAHE 180 L + + + +LFL G +L++ L ++ LP G S + Sbjct: 117 ASHLNMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAG 176 Query: 181 WQLMCQLCLSFAMPAMVIMILVDVALGLVNRSAQQLNVFFLSMPIKSALVLLLLIYSL 238 + L A+P + +++ +++ALGL+NR A QL++F + P+ + + L+ + Sbjct: 177 SLIF-LNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALM 233
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 356 bits (915), Expect = e-124 Identities = 120/346 (34%), Positives = 192/346 (55%) Query: 2 AEKTEKPTEKRLREARNRGQVIKSAEIVTGLQMAIILGYFLYEGPALVQAIMALIDLTIH 61 EKTE+PT K++R+AR +GQV KS E+V+ + + + + L+ + Sbjct: 3 GEKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLMLIPAE 62 Query: 62 AINLPLETAAEQIVGTFAVLALRFLGGLTLVLVFTIVVGNLVQTGPVWAAESIMPSMDKL 121 LP A +V + L V + ++VQ G + + E+I P + K+ Sbjct: 63 QSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDIKKI 122 Query: 122 NVMNNAKQLISLKSLFELAKNLVKVTVLSLVFYYLLHRYVNAFQYLPLCGEACGISVIST 181 N + AK++ S+KSL E K+++KV +LS++ + ++ + LP CG C ++ Sbjct: 123 NPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLLGQ 182 Query: 182 MITWLWGSFLGCYLIFGIADYAFQRYSLMKELKMSKDDTKQEYKDSEGNPEMKQKRRETQ 241 ++ L +++ IADYAF+ Y +KELKMSKD+ K+EYK+ EG+PE+K KRR+ Sbjct: 183 ILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKRRQFH 242 Query: 242 REVASGSLASNVRKATVVVRNPTHIAVCLYYSEGETPLPKVLEKAEDHMALHIVALAEKA 301 +E+ S ++ NV++++VVV NPTHIA+ + Y GETPLP V K D + +AE+ Sbjct: 243 QEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIAEEE 302 Query: 302 GVPIVENIPLARALFKHVEAGDVIPESLFEPVAELLRLVMTISYDN 347 GVPI++ IPLARAL+ IP E AE+LR + + + Sbjct: 303 GVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQNIEK 348
>adhesinb#Adhesin B signature. Length = 310 Score = 28.7 bits (64), Expect = 0.019 Identities = 27/120 (22%), Positives = 45/120 (37%), Gaps = 27/120 (22%) Query: 140 AWTDVSASANKLRIAIETLLTTIDPE------------LAKIKVLHERIEAFSKSQPEVA 187 AW ++ + I L+ DP + K+ L + + + P Sbjct: 141 AWLNLE-NGIIYAQNIAKRLSEKDPANKETYEKNLKAYVEKLSALDKEAKEKFNNIPGEK 199 Query: 188 KLLMAIKWLGNEASHEGALKEYDLAFAYEVMELSINRLFDDSE---DKIKQLVELVNKNK 244 K+++ + EG K Y + AY V I + + E D+IK LVE + K K Sbjct: 200 KMIV---------TSEGCFK-Y-FSKAYNVPSAYIWEINTEEEGTPDQIKTLVEKLRKTK 248
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 52.9 bits (127), Expect = 2e-09 Identities = 16/118 (13%), Positives = 37/118 (31%), Gaps = 11/118 (9%) Query: 513 DQQKVLIIDDNLFNLEICRAMLEHYHFQTFSTDNTEQALKMLVNHLPQIVIVDYRLQGMN 572 +L+ DD+ + L + T N + + +V+ D + N Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 573 GLQLVRQMQQVLQSLESNSPIEHQCRFFLLSA-NDCDDIPELASFPEVHFMQKPFSAE 629 L+ ++++ ++SA N + + ++ KPF Sbjct: 62 AFDLLPRIKK----------ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLT 109
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 30.6 bits (69), Expect = 0.028 Identities = 12/49 (24%), Positives = 23/49 (46%), Gaps = 4/49 (8%) Query: 691 RYRFLNAQNLPLAPAMQGDSSDFYQRPLQQVLREQRWFVLAGRAAQIEK 739 Y+ L+AQ + DS+ R +Q+LRE+ L+ + ++ Sbjct: 5 HYQALDAQGKKCRGTQEADSA----RQARQLLRERGLVPLSVDENRGDQ 49
>PF04183#IucA / IucC family Length = 580 Score = 30.2 bits (68), Expect = 0.009 Identities = 11/47 (23%), Positives = 20/47 (42%), Gaps = 2/47 (4%) Query: 251 RLPSSHFTFNQDIMVLGKFSIPALSERVTPTYLGNEIRTLITHAQQV 297 LP + + F + + G I A + R + +TL+ +QV Sbjct: 40 NLPGAQWRFIAERGIWGWLWIDAQTLRCADEPV--LAQTLLMQLKQV 84
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 297 bits (761), Expect = 3e-93 Identities = 111/418 (26%), Positives = 187/418 (44%), Gaps = 65/418 (15%) Query: 384 QPGDVLVTDMTDPDWEPIMK-RASAIVTNRGGRTCHAAIIARELGVPAVVGCGDVTDRIK 442 + ++ D+T D + K T+ GGRT H+AI++R L +PAVVG +VT++I+ Sbjct: 155 EETVIIAEDLTPSDTAQLNKQFVKGFATDIGGRTSHSAIMSRSLEIPAVVGTKEVTEKIQ 214 Query: 443 NGQIVTVSCAEG---------DTGFIYEGKQEFEVISNRVDSLPELP--------MKIMM 485 +G +V V EG + E + FE L P +++ Sbjct: 215 HGDMVIVDGIEGIVIVNPTEEEVKAYEEKRAAFEKQKQEWAKLVGEPSTTKDGAHVELAA 274 Query: 486 NVGNPDRAFDFARLPNEGVGLARLEFIINRMIGIHPKALLEFNQQDAALQTEINEMIAGY 545 N+G P EG+GL R EF+ M L TE E Y Sbjct: 275 NIGTPKDVDGVLANGGEGIGLYRTEFLY--MD-------------RDQLPTE-EEQFEAY 318 Query: 546 ESPVEFYIARLVEGIATIGSAFYPKKVIVRMSDFKSNEYANLVGGDRYEPEEENPMLGFR 605 + V+ K V++R D ++ + + P+E NP LGFR Sbjct: 319 KEVVQ---------------RMDGKPVVIRTLDIGGDKELSYL----QLPKELNPFLGFR 359 Query: 606 GASRYISESFRDCFALECEAIKRVRNDMGLKNVEVMIPFVRTVKEAEQVIGLLKEQGLER 665 + + +D F + A+ R N++VM P + T++E Q +++E+ + Sbjct: 360 AIRLCLEK--QDIFRTQLRALLRAS---TYGNLKVMFPMIATLEELRQAKAIMQEEKDKL 414 Query: 666 GKDG------LRVIMMCEVPSNALLADQFLEHFDGFSIGSNDLTQLTLGLDRDSGIISHL 719 +G + V +M E+PS A+ A+ F + D FSIG+NDL Q T+ DR + +S+L Sbjct: 415 LSEGVDVSDSIEVGIMVEIPSTAVAANLFAKEVDFFSIGTNDLIQYTMAADRMNERVSYL 474 Query: 720 FDERDEAVKMLLSLAIKAAKTKGAYIGICGQGPSDHADFAAWLVEQGIDTVSLNPDTV 777 + A+ L+ + IKAA ++G ++G+CG+ D L+ G+D S++ ++ Sbjct: 475 YQPYHPAILRLVDMVIKAAHSEGKWVGMCGEMAGDE-VAIPLLLGLGLDEFSMSATSI 531
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 35.8 bits (82), Expect = 0.001 Identities = 34/162 (20%), Positives = 58/162 (35%), Gaps = 28/162 (17%) Query: 81 WENKGVCDGAQNQAPTLVILQPQNNVSVNLGDVVLLQADAS-DVDGTVASVNW-FANGQA 138 D N+ P VI +++ SV + + + S D DG + + W F +G+ Sbjct: 761 MNTDTNTDVHVNKEPKAVI---KSDSSVIVEEEINFDGTESKDEDGEIKAYEWDFGDGEK 817 Query: 139 VTSPWTT---NAIGSVQLKAVATDDKGATTEKSVVLTVINPTSENLPPMIEILLLVNDSA 195 T N G ++K TD+ G +S + V+ + +I N+S Sbjct: 818 SNEAKATHKYNKTGEYEVKLTVTDNNGGINTESKKIKVV---EDKPVEVI------NESE 868 Query: 196 VNVGDSVTITANASDPDTGDSITKVEFYLDSQLIATDNSAPY 237 N +D + + I K + L D S Y Sbjct: 869 PN-----------NDFEKANQIAKSNMLVKGTLSEEDYSDKY 899
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 29.1 bits (65), Expect = 0.007 Identities = 13/44 (29%), Positives = 25/44 (56%), Gaps = 1/44 (2%) Query: 79 VTVSSDRIDFKKPIPAGTLAELIARVIHVGNTSLKVEVNIYVED 122 V V+ + K I GT+ + RV+ G+ S ++ +N+++ED Sbjct: 383 VKVTGKEVAELKGITYGTMLRMTPRVLTQGDKS-EISLNLHIED 425
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 79.5 bits (196), Expect = 2e-19 Identities = 32/111 (28%), Positives = 54/111 (48%), Gaps = 6/111 (5%) Query: 8 IIIADDHPLFRNALRQALTTAFEHAQWFEADSAEALQSVL-DVRSIDYDLVLLDLQMPGS 66 I++ADD R L QAL+ A ++ ++ + + D DLV+ D+ MP Sbjct: 6 ILVADDDAAIRTVLNQALSRAG-----YDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 67 HGYSTLIHLRSHYPDLPVVVISAHEDINTISRAIHYGSSGFIPKSASMETL 117 + + L ++ PDLPV+V+SA T +A G+ ++PK + L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTEL 111
>INTIMIN#Intimin signature. Length = 939 Score = 42.4 bits (99), Expect = 1e-05 Identities = 48/204 (23%), Positives = 80/204 (39%), Gaps = 17/204 (8%) Query: 30 GGTTPTPGVVTVTLSISNSDSVSVATPAEVKATVVDSKTGPLAGVVVSFKLDNDALGSFT 89 G GV T +++ + ATV + A V VSF + + G+ Sbjct: 552 GQVVDQVGVTDFTADKTSAKADG-TEAITYTATVKKNGV-AQANVPVSFNIVS---GTAV 606 Query: 90 PSTGTQLTDSSGVATVKLDTATLAGAGNVTASVASGASITKGFYSKGDGVVQPGTGNKLK 149 S + T+ SG ATV L + G V+A A S + V+ Sbjct: 607 LSANSANTNGSGKATVTLKSDKP-GQVVVSAKTAEMTSAL-----NANAVIFVDQTKASI 660 Query: 150 LSLQNVQGQTVTKISSAVPGTVSAIYTNGSDEPLVGKVITFTSNLGKFSPQSGTALTNAQ 209 ++ + V A+ TV + D+P+ + +TFT+ LGK S + T+ Sbjct: 661 TEIKADKTTAVANGQDAITYTVKVMK---GDKPVSNQEVTFTTTLGKLSNSTEK--TDTN 715 Query: 210 GLAKIAITAGPVAGAGNIIAKVDE 233 G AK+ +T+ G + A+V + Sbjct: 716 GYAKVTLTST-TPGKSLVSARVSD 738 Score = 40.1 bits (93), Expect = 6e-05 Identities = 64/299 (21%), Positives = 98/299 (32%), Gaps = 40/299 (13%) Query: 378 TGLPTTNVSAAQPSKVTVTL---VDKDATPLVGKVVSFSSSLGNFLPTKGTALTDSIGRA 434 T SA +T V K+ VSF+ G + + +A T+ G+A Sbjct: 561 TDFTADKTSAKADGTEAITYTATVKKNGVAQANVPVSFNIVSGTAVLSANSANTNGSGKA 620 Query: 435 SITLTAGSIEGAGEVTASY--GTAKAIVGFVTAGDDIDPIEASPEISFDIYDCNGVAAWD 492 ++TL + G V+A T+ V D + NG A Sbjct: 621 TVTLKSDKP-GQVVVSAKTAEMTSALNANAVIFVDQTKASITEIKADKTTAVANGQDAIT 679 Query: 493 KTLKNFEVCKITDNITNDKPGIIGAKVTRSGSTQALQQVLVTAATTLGAISPNSGTAITN 552 T+K + DKP + +VT + TTLG ++ T T+ Sbjct: 680 YTVKVMK---------GDKP-VSNQEVTFT--------------TTLGK--LSNSTEKTD 713 Query: 553 ADGKAILDLYANGNVGAGEVSLKVKD-ATSTKAFEI---GRVNISLDIKTSVGNNSLPAG 608 +G A + L + G VS +V D A KA E+ + I VG Sbjct: 714 TNGYAKVTLTST-TPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGTGVKGKL 772 Query: 609 GSTIVEVTVFNPDGSLSTGQPFTLEFSSECVAAGKAVIDSPIVTNAGKGYSTYRSTGCS 667 + ++ N S G+ + S A S VT KG +T Sbjct: 773 PTVWLQYGQVNLKASGGNGK---YTWRSANPAIASVDASSGQVTLKEKGTTTISVISSD 828
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 33.3 bits (76), Expect = 0.001 Identities = 35/139 (25%), Positives = 53/139 (38%), Gaps = 19/139 (13%) Query: 28 LIALIANG--HLLVEGPPGLAKT---RAVKALCDGVEGDFHRIQ---FTPDLLPADLTG- 78 ++A + L++ G G K RA+ G F I DL+ ++L G Sbjct: 152 VLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGH 211 Query: 79 -----TDIYRSQTGTFEFEAGPIFHNLILADEINRAPAKVQSALLEAMAEGQVT-VGKHS 132 T TG FE G + DEI P Q+ LL + +G+ T VG + Sbjct: 212 EKGAFTGAQTRSTGRFEQAEG----GTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRT 267 Query: 133 YKLPPLFLVMATQNPLENE 151 + +V AT L+ Sbjct: 268 PIRSDVRIVAATNKDLKQS 286
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 170 bits (433), Expect = 2e-49 Identities = 69/217 (31%), Positives = 110/217 (50%), Gaps = 10/217 (4%) Query: 152 STPWGQTFVGATQLSDSQAG-NRTICIIDSGYDRSHSELGGNNVTGTN--NSGTGNWFEP 208 P G + A + + G + ++D+G D H +L + G N + G+ Sbjct: 21 EIPRGVEMIQAPAVWNQTRGRGVKVAVLDTGCDADHPDLKARIIGGRNFTDDDEGDPEIF 80 Query: 209 GNNNAHGTHVAGTIAAIANNDGVIGVMPNQTANIHVVKVFNESGWGYSSSLVAAVDTCVA 268 + N HGTHVAGTIAA N +GV+GV P A++ ++KV N+ G G ++ + + Sbjct: 81 KDYNGHGTHVAGTIAATENENGVVGVAPE--ADLLIIKVLNKQGSGQYDWIIQGIYYAIE 138 Query: 269 NGANVVTMSLGGAGSSTTERNALAAHYNNGVLLIAAAGNAGDSTHS-----YPASYDGVM 323 ++++MSLGG A+ + +L++ AAGN GD YP Y+ V+ Sbjct: 139 QKVDIISMSLGGPEDVPELHEAVKKAVASQILVMCAAGNEGDGDDRTDELGYPGCYNEVI 198 Query: 324 SVASVDNHKDHSAFSQYTNQVEISGPGEAILSTVTRG 360 SV +++ + S FS N+V++ PGE ILSTV G Sbjct: 199 SVGAINFDRHASEFSNSNNEVDLVAPGEDILSTVPGG 235 Score = 63.3 bits (154), Expect = 1e-12 Identities = 19/71 (26%), Positives = 29/71 (40%), Gaps = 7/71 (9%) Query: 507 NKDYEYYNGTSMATPHVSGVATLVWS-----YHPECSAAQVRNALKMTAEDLGTAGRDNY 561 Y ++GTSMATPHV+G L+ + + + ++ L LG Sbjct: 234 GGKYATFSGTSMATPHVAGALALIKQLANASFERDLTEPELYAQLIKRTIPLG--NSPKM 291 Query: 562 YGYGLVNAVAA 572 G GL+ A Sbjct: 292 EGNGLLYLTAV 302
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 316 bits (811), Expect = e-110 Identities = 113/309 (36%), Positives = 180/309 (58%), Gaps = 14/309 (4%) Query: 2 LEILSLKHTVNFLRHALPISIMSAVLVLGSLVSLATNGINWGLDFTGGTVVEMEFTNPVD 61 L+++ K +F R + V+++ S++ G+N+G+DF GGT + E T +D Sbjct: 5 LKLVPEKTNFDFFRWQWATFGAAIVMMIASVILPLVIGLNFGIDFKGGTTIRTESTTAID 64 Query: 62 LNALRVQLTTPDSEGAIVQNFGSSR------DVLVRLQVKE--------GVKSDVQVKSV 107 + R L + I+ ++R+Q++E G + V V Sbjct: 65 VGVYRAALEPLELGDVIISEVRDPSFREDQHVAMIRIQMQEDGQGAEGQGAQGQELVNKV 124 Query: 108 MEAAQKVDPQVQQKRVEFVGPQVGKELAEQGALAVLVALICIMIYVSFRFEWRLAFGSVA 167 A VDP ++ E VGP+V EL ++L A + IM Y+ RFEW+ A G+V Sbjct: 125 ETALTAVDPALKITSFESVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGAVV 184 Query: 168 ALAHDVIVTLGVFSVFQLEFDLTVLAGLLTVVGYSLNDTIVVFDRIRENFLKMRKSDPEE 227 AL HDV++T+G+F+V QL+FDLT +A LLT+ GYS+NDT+VVFDR+REN +K + + Sbjct: 185 ALVHDVLLTVGLFAVLQLKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRD 244 Query: 228 VVNTSITQTMSRTIITTGTTLVVVVALFLKGGTMIHGFATALLMGIFVGTYSSIYVASFL 287 V+N S+ +T+SRT++T TTL+ +V + + GG +I GF A++ G+F GTYSS+YVA + Sbjct: 245 VMNLSVNETLSRTVMTGMTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAKNI 304 Query: 288 AIKLGINRE 296 + +G++R Sbjct: 305 VLFIGLDRN 313
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 78.7 bits (194), Expect = 6e-18 Identities = 31/165 (18%), Positives = 80/165 (48%), Gaps = 4/165 (2%) Query: 434 VSIVEERTIGPSLGAENIQNGVQAMVWGMAVVLLFMLVYYR-GFGLIANIALTANLVMVV 492 + I ++GP + E + V +++ V++ ++ V + F L A +AL ++++ V Sbjct: 135 LKITSFESVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGAVVALVHDVLLTV 194 Query: 493 GVMSMIPGAVLTLPGIAGMVLTVGMAVDGNVLIYERIREELRA--GRSVQQAIHEGYGNA 550 G+ +++ L +A ++ G +++ V++++R+RE L ++ ++ Sbjct: 195 GLFAVL-QLKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRDVMNLSVNET 253 Query: 551 FSTIADANITTFLTALILFAVGTGAVKGFAVTLMIGIATSMFTAI 595 S +TT L + + G ++GF ++ G+ T ++++ Sbjct: 254 LSRTVMTGMTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSV 298
>AEROLYSIN#Aerolysin signature. Length = 493 Score = 30.4 bits (68), Expect = 0.011 Identities = 16/42 (38%), Positives = 21/42 (50%), Gaps = 1/42 (2%) Query: 79 DTTQSDRQAIDPTDLDALGY-DCTQTNFDTALRYAKIDMWAK 119 D TQSDRQ + A+ D Q+ +D LRY W+K Sbjct: 211 DVTQSDRQLVKTVVGWAVNDSDTPQSGYDVTLRYDTATNWSK 252
>PF03309#Bvg accessory factor Length = 271 Score = 30.5 bits (69), Expect = 0.015 Identities = 20/85 (23%), Positives = 28/85 (32%), Gaps = 4/85 (4%) Query: 267 VASGMAIHAKWRQTY-ISTPSSITHDAYPFWTGTLFNRGRPKADRIEI-DVSHSALANGR 324 + SG HAK Q + I T +T D L + S L R Sbjct: 16 LISGSGDHAKVVQQWRIRTEPEVTADELALTIDGLIGDDAERLTGASGLSTVPSVLHEVR 75 Query: 325 RCEDGQWRQV--VTVDDAIRKGCNL 347 + W V V ++ +R G L Sbjct: 76 VMLEQYWPNVPHVLIEPGVRTGIPL 100
>FIMREGULATRY#Escherichia coli: P pili regulatory PapB protein signature. Length = 104 Score = 40.3 bits (94), Expect = 5e-08 Identities = 18/72 (25%), Positives = 33/72 (45%) Query: 3 TLIQGCESTEQFEILLKLTGITSEDKKNALRAHLVEGLPAKRAYARFHVTQQHFSLALML 62 L+ G S F +L+ ++ I S+ A++ +LV G K ++ + +FS L Sbjct: 22 VLLPGSMSEMHFFLLIGISSIHSDRVILAMKDYLVGGHSRKEVCEKYQMNNGYFSTTLGR 81 Query: 63 LNKKADLAMQYV 74 L + LA + Sbjct: 82 LIRLNALAARLA 93
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 46.7 bits (111), Expect = 2e-07 Identities = 27/169 (15%), Positives = 57/169 (33%), Gaps = 25/169 (14%) Query: 24 KVAIIDDEPGIHEVTRFALKNLTLDNRVLQFYSCYSAAEGLALLQTETDIALAFIDVVME 83 + + DD+ I V AL D R +AA + L DVVM Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVR-----ITSNAATLWRWIAAGD-GDLVVTDVVMP 58 Query: 84 TDHAGLELVQKIRTELNNHSTRIILRTGQ--PGQAPE-------DQVIRDFDINDYKAKT 134 D +L+ +I+ +++ + Q A + D + + FD+ + Sbjct: 59 -DENAFDLLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGII 115 Query: 135 ELTAARLKSCVYTSLRSYRDIK-IIEQSQ------KGMEKVIAASTSVL 176 A K +D ++ +S + + +++ +++ Sbjct: 116 GRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLM 164
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 188 bits (479), Expect = 2e-59 Identities = 83/361 (22%), Positives = 138/361 (38%), Gaps = 53/361 (14%) Query: 1 MRVLVTGGAGFIGSALVRMLIEQTTCVVINFDKLTYASDL---ESLASIADSERYHFIQA 57 M+ LVTG AGFIG + + L+E V+ D L D+ ++ + + F + Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGH-QVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKI 59 Query: 58 DIGDRAKLDQVFQDYLPDVVMHLAAESHVDRSINGPAEFIQTNIVGTYTLLEACRCYFQS 117 D+ DR + +F + V V S+ P + +N+ G +LE CR Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCR----- 114 Query: 118 LNTDKQKVFRFHHISTDEVYGSLGDTGLFSETTAYD-PSSPYSASKASADHLVRAWHRTY 176 K+ + S+ VYG L FS + D P S Y+A+K + + + + Y Sbjct: 115 ----HNKIQHLLYASSSSVYG-LNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLY 169 Query: 177 GLPIVITNCSNNYGPFQYPEKLIPLMVLNALAGKQLPVYGNGQQVRDWLYVDDHVRALFL 236 GLP YGP+ P+ + L GK + VY G+ RD+ Y+DD A+ Sbjct: 170 GLPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIR 229 Query: 237 VV------------------TQGTVGETYNIGGTNERSNLEVVHQICDLLEELVPTHAQA 278 + YNIG ++ ++ + LE+ Sbjct: 230 LQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYI----QALEDA------- 278 Query: 279 LAADGVGFRSLVEHVTDRAGHDVR--YAIDASKIQRELGWQPLESFDSGLRKTVEWIVAR 336 +G + + + G DV A D + +G+ P + G++ V W Sbjct: 279 -----LGIEAKKNMLPLQPG-DVLETSA-DTKALYEVIGFTPETTVKDGVKNFVNWYRDF 331 Query: 337 Y 337 Y Sbjct: 332 Y 332
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 174 bits (443), Expect = 7e-54 Identities = 81/361 (22%), Positives = 141/361 (39%), Gaps = 51/361 (14%) Query: 1 MKVLVTGGAGFIGSAVVRHIICNTQDSVINVDKLT--YAGNLESLT-SVADNARYTFEKV 57 MK LVTG AGFIG V + ++ V+ +D L Y +L+ + + F K+ Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAG-HQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKI 59 Query: 58 DICDRGELDRIFLQYQPDAIMHLAAESHVDRSITGPSDFIQTNIIGTYTLLEAARHYWIQ 117 D+ DR + +F + + V S+ P + +N+ G +LE RH IQ Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ 119 Query: 118 LDSERKAAFRFHHISTDEVYGDLPHPDEHEGQVVNQELPLFTETTPYAPSSPYSASKASS 177 + S+ VYG N+++P T+ + P S Y+A+K ++ Sbjct: 120 ---------HLLYASSSSVYGL------------NRKMPFSTDDSVDHPVSLYAATKKAN 158 Query: 178 DHLVRAWLRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEGKPLPIYGKGDQIRDWL 237 + + + YGLP YGP+ P+ + LEGK + +Y G RD+ Sbjct: 159 ELMAHTYSHLYGLPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFT 218 Query: 238 YVEDHARALYKVV------------------TEGKVGETYNIGGHNEKRNLEVVQTICSI 279 Y++D A A+ ++ YNIG + ++ +Q + Sbjct: 219 YIDDIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDA 278 Query: 280 LDVLMPKGTPYAEQITYVTDRLGHDRRYAIDASKMSAELNWQPQETFETGLLKTVEWYLA 339 L + K + + G + D + + + P+ T + G+ V WY Sbjct: 279 LGIEAKK--------NMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRD 330 Query: 340 N 340 Sbjct: 331 F 331
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 26.4 bits (58), Expect = 0.032 Identities = 23/98 (23%), Positives = 46/98 (46%), Gaps = 13/98 (13%) Query: 4 QKLEVWQ--LSYELSSSIYIATKDLRDWGFRDQITRSGLSVPSN---IAEGMERYGAKEQ 58 K + W L Y+ +++IY+AT + +T G + +A + + Q Sbjct: 243 DKADAWTAGLKYD-ANNIYLATM----YSETRNMTPYGKTDKGYDGGVANKTQNFEVTAQ 297 Query: 59 IQFLYIAKASLAELITQAMIGKDIGYLEPNYVDELLIK 96 QF + + +++ L+++ GKD+ Y N D+ L+K Sbjct: 298 YQFDFGLRPAVSFLMSK---GKDLTYNNVNGDDKDLVK 332
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.9 bits (223), Expect = 8e-22 Identities = 29/114 (25%), Positives = 49/114 (42%), Gaps = 4/114 (3%) Query: 8 VLLVEDDPVFRQIVASFLDTRGAQVTQACDGEEGLSLFKSQHFDIVLADLSMPKLGGLDM 67 +L+ +DD R ++ L G V + + D+V+ D+ MP D+ Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 68 LKEMTRLAPLVPSVVISGNNVMADVVEALRIGASDYLVKPVSDLFIIEQAIKQS 121 L + + P +P +V+S N ++A GA DYL KP F + + I Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKP----FDLTELIGII 115
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 229 bits (586), Expect = 1e-77 Identities = 85/222 (38%), Positives = 128/222 (57%), Gaps = 4/222 (1%) Query: 44 PRDPFEGFNRAMWDFNYLFLDRYLYRPVAHGYNDYIPMPAKTGVNNFVQNLEEPSSLVNN 103 DP EGFNR M++FN+ LD Y+ RPVA + DY+P PA+ G++NF NLEEP+ +VN Sbjct: 28 RSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWRDYVPQPARNGLSNFTGNLEEPAVMVNY 87 Query: 104 VLQGKWGWAANAGGRFTINSTVGLLGVIDVADMMGMSRKQDE---FNEVLGYYGVPNGPY 160 LQG RF +N+ +G+ G IDVA M ++ E F LG+YGV GPY Sbjct: 88 FLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGMANPKLQRTEPHRFGSTLGHYGVGYGPY 147 Query: 161 FMAPFAGPYVVRELASDWVDGLYFPLSELTIWQTIVKWGLKNLHSRASAIDQERLVDNAL 220 PF G + +R+ D D LY LS LT ++ KW L+ + +RA +D + L+ + Sbjct: 148 VQLPFYGSFTLRDDGGDMADALYPVLSWLTWPMSVGKWTLEGIETRAQLLDSDGLLRQSS 207 Query: 221 DPYAFVKDAYLQHMDYKVYDGNV-PQKQDDDELLDQYMQELE 261 DPY V++AY Q D+ G + PQ+ + + + +++++ Sbjct: 208 DPYIMVREAYFQRHDFIANGGELKPQENPNAQAIQDDLKDID 249
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 33.1 bits (75), Expect = 0.005 Identities = 68/359 (18%), Positives = 129/359 (35%), Gaps = 26/359 (7%) Query: 278 GIPLSNTNKGPVTNLNGSSGSSSSLNSQTQATQATQATQATQATQATQATQATQATQATQ 337 G+P + + +T LNG+ S S + ++++ A AT A +T + TQA Q Sbjct: 11 GVPYDDKGQVIITLLNGTPDGSGSGGGGGKGGSKSESSAAIHAT-AKWSTAQLKKTQAEQ 69 Query: 338 ATQATQATQATQATQATQATQATQ-------------ATQATQATQATQATQATQATQAT 384 A +A A +A QA TQ A++ AT+ A A + Sbjct: 70 AARAKAAAEA-QAKAKANRDALTQRLKDIVNEALRHNASRTPSATELAHANNAAMQAEDE 128 Query: 385 QATQATQATQATQATQATQATQATQATQATQATQATQATQATQATQATQATQATQATKTN 444 + A +A + +A A +A Q + + + + + + +A + A + Sbjct: 129 RLRLAKAEEKARKEAEA--AEKAFQEAEQRRKEIEREKAETERQLKLAEAEEKRLAALSE 186 Query: 445 DAIPVKVTMPTMLSARGSNQSLATPSVLINSTQSQINQPSSATATIEQTTRNSSPLGFSL 504 +A V++ + +A+ + +NS S A RN L Sbjct: 187 EAKAVEIAQKKLSAAQSEVVKMDGEIKTLNSRLSSSIHARDAEMKTLAGKRN------EL 240 Query: 505 ATASLNVPSQDPKVNNVLVMQN-PKSLAPTPPLTNVATNIGAQNEEAVEEI-AAVSPKNI 562 A AS D V + N P P T G EE +++ A+ + N Sbjct: 241 AQASAKYKELDELVKKLSPRANDPLQNRPFFEATRRRVGAGKIREEKQKQVTASETRINR 300 Query: 563 LGLNTQKNERHGNDTKTDSTMKVADVLQKAFN-KAGALPVELSRSNNSSNLASELLKHL 620 + + + ++ + + +A V + N K + S+ ++ + + L Sbjct: 301 INADITQIQKAISQVSNNRNAGIARVHEAEENLKKAQNNLLNSQIKDAVDATVSFYQTL 359
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 56.3 bits (136), Expect = 7e-13 Identities = 16/93 (17%), Positives = 34/93 (36%), Gaps = 9/93 (9%) Query: 10 AVALSYDGRN--APKIVATGEGLIAEEIIALAKANGVYIHQDPHLSHFL-QLLELGEEIP 66 A+ + Y P + + + +A+ GV I Q L+ L + IP Sbjct: 268 AIGILYKRGETPLPLVTFKYTDAQVQTVRKIAEEEGVPILQRIPLARALYWDALVDHYIP 327 Query: 67 KELYLLIAELIAFVYMLDGKFPEQWNNMHQKIV 99 E AE++ ++ + + H +++ Sbjct: 328 AEQIEATAEVLRWLERQNIE------KQHSEML 354
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 455 bits (1171), Expect = e-160 Identities = 167/483 (34%), Positives = 250/483 (51%), Gaps = 42/483 (8%) Query: 1 MSEAKLLLVEDDASLREALLDTLMLAQYECIDVASGEDAILALKQHQFDLVISDVQMQGI 60 M+ A +L+ +DDA++R L L A Y+ ++ + DLV++DV M Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 GGLGLLNFLQQHHPKLPVLLMTAYATIGSAVDAIKLGAVDYLAKPFAPEVLLNQVSRYLP 120 LL +++ P LPVL+M+A T +A+ A + GA DYL KPF L+ + R L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 121 LKQNVDQPVVAD-----------EKSLALLALAQRVAASDASVMILGPSGSGKEVLARYI 169 + + D + + R+ +D ++MI G SG+GKE++AR + Sbjct: 121 EPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARAL 180 Query: 170 HQHSSRADQAFVAINCAAIPENMLEATLFGYEKGAFTGAYQACPGKFEQAQGGTLLLDEI 229 H + R + FVAIN AAIP +++E+ LFG+EKGAFTGA G+FEQA+GGTL LDEI Sbjct: 181 HDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEI 240 Query: 230 SEMDLGLQAKLLRVLQEREVERLGGRKIIKLDVRVLATSNRDLKAVVAAGGFREDLYYRI 289 +M + Q +LLRVLQ+ E +GGR I+ DVR++A +N+DLK + G FREDLYYR+ Sbjct: 241 GDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRL 300 Query: 290 NVFPLAWPALSQRPADILPLARHLLVKHAKALNVADVPELDENARRRLLSHRWPGNVREL 349 NV PL P L R DI L RH + + A+ + V D+ A + +H WPGNVREL Sbjct: 301 NVVPLRLPPLRDRAEDIPDLVRHFV-QQAEKEGLD-VKRFDQEALELMKAHPWPGNVREL 358 Query: 350 DNVIQRALILRAGQVITANDIIIDAQDVILGA--------------------------ED 383 +N+++R L VIT I + + I + Sbjct: 359 ENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFAS 418 Query: 384 LDQFVAEPDGLGEELKAQEHVIILETLNQCQGSRKLVAEKLGISARTLRYKMARMRDMGI 443 + L E+ +IL L +G++ A+ LG++ TLR K +R++G+ Sbjct: 419 FGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKK---IRELGV 475 Query: 444 QLP 446 + Sbjct: 476 SVY 478
>PF06580#Sensor histidine kinase Length = 349 Score = 34.1 bits (78), Expect = 7e-04 Identities = 19/95 (20%), Positives = 37/95 (38%), Gaps = 19/95 (20%) Query: 256 LVMNSIEAGAT------EIRIQAKEEGDQLLLNVIDNGKGLDANMQQKVLEPFFTTKSQG 309 LV N I+ G +I ++ ++ + L V + G N + + Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTK------------ES 310 Query: 310 TGLGLA-VVQSVVRNHGGQLQLSCLPNKGCTVSLV 343 TG GL V + + +G + Q+ +G ++V Sbjct: 311 TGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMV 345
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 433 bits (1114), Expect = e-151 Identities = 171/481 (35%), Positives = 262/481 (54%), Gaps = 21/481 (4%) Query: 7 RILLIGPSSERLNRLCCIFDFLGEQIAQI-DAEKLSASLQDTRFRALVILTDVMDADA-- 63 IL+ + L G + +A L + +++TDV+ D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGD--LVVTDVVMPDENA 62 Query: 64 ---LKNIAGQHPWQPMLLL---GNVDDLQVSNILG---NIEEPLTYPQLTELLHFCQVFG 114 L I P P+L++ ++ G + +P +L ++ Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 115 QVKRPQVPTSANQTKLFRSLVGRSDGIANVRHLINQVATSEATVLVLGQSGTGKEVVARN 174 + + ++ + LVGRS + + ++ ++ ++ T+++ G+SGTGKE+VAR Sbjct: 123 KRRPSKLEDDSQD---GMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARA 179 Query: 175 IHYLSERRDGPFIPVNCGAIPPELLESELFGHEKGSFTGAICSRKGRFELAEGGTLFLDE 234 +H +RR+GPF+ +N AIP +L+ESELFGHEKG+FTGA GRFE AEGGTLFLDE Sbjct: 180 LHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDE 239 Query: 235 IGDMPLQMQVKLLRVLQERVFERVGGTKTINADVRVVAATHRDLETMISVNEFREDLYYR 294 IGDMP+ Q +LLRVLQ+ + VGG I +DVR+VAAT++DL+ I+ FREDLYYR Sbjct: 240 IGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYR 299 Query: 295 LNVFPIEMPALCDRKDDVPLLLQELVSRVYNEGRGKVRFTQRAIESLKEHAWSGNVRELS 354 LNV P+ +P L DR +D+P L++ V + EG RF Q A+E +K H W GNVREL Sbjct: 300 LNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELE 359 Query: 355 NLVERLTILYPGGLVDVNDLPVKYRHIDVPEYCVEMSEEQQERDALASIFSDEEPVEIPE 414 NLV RLT LYP ++ + + R ++P+ +E + + +++ EE + Sbjct: 360 NLVRRLTALYPQDVITREIIENELRS-EIPDSPIEKAAARSGSLSISQAV--EENMRQYF 416 Query: 415 TRFPSELPPEGVNLKDLLAELEIDMIRQALELQDNVVARAAEMLGIRRTTLVEKMRKYGM 474 F LPP G+ +LAE+E +I AL +AA++LG+ R TL +K+R+ G+ Sbjct: 417 ASFGDALPPSGL-YDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGV 475 Query: 475 T 475 + Sbjct: 476 S 476
>FLAGELLIN#Flagellin signature. Length = 507 Score = 139 bits (352), Expect = 2e-40 Identities = 94/270 (34%), Positives = 129/270 (47%), Gaps = 9/270 (3%) Query: 2 AITVNTNVTSMKAQKNLNASGNALATSMERLSSGLRINSAKDDAAGLAISNRLNSQVRGL 61 A +NTN S+ Q NLN S ++L++++ERLSSGLRINSAKDDAAG AI+NR S ++GL Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 DVGMRNANDGISVAQIAEGAMQEQTNMLQRMRDLSVQAVNGANSTSDRDALQAEIDQLAL 121 RNANDGIS+AQ EGA+ E N LQR+R+LSVQA NG NS SD ++Q EI Q Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 EITAISSTTAFGDTKLLDSSFAGKSFQVGHQEGENISISISGTNATALGVNAL------- 174 EI +S+ T F K+L QVG +GE I+I + + +LG++ Sbjct: 121 EIDRVSNQTQFNGVKVLSQDN-QMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKE 179 Query: 175 -AVSTDILASTATGAIDDAIKAIDTQRAKLGATQNRLSHNISNSANTQANVADAKSRIVD 233 V + D + R + + + A D Sbjct: 180 ATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTD 239 Query: 234 VDFAKETSQMTKNQVLQQTGSAMLAQANQL 263 + K + A A + Sbjct: 240 DAENNTAVDLFKTTKSTAGTAEAKAIAGAI 269 Score = 83.2 bits (205), Expect = 3e-20 Identities = 57/265 (21%), Positives = 97/265 (36%) Query: 7 TNVTSMKAQKNLNASGNALATSMERLSSGLRINSAKDDAAGLAISNRLNSQVRGLDVGMR 66 N T++ K ++ + D G+ + + G Sbjct: 242 ENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGNGKVST 301 Query: 67 NANDGISVAQIAEGAMQEQTNMLQRMRDLSVQAVNGANSTSDRDALQAEIDQLALEITAI 126 N +A+ ++ + N D ++ A Sbjct: 302 TINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSDLEAN 361 Query: 127 SSTTAFGDTKLLDSSFAGKSFQVGHQEGENISISISGTNATALGVNALAVSTDILASTAT 186 ++ + + + + + + +N A + + Sbjct: 362 NAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINEDAAAAKKSTANPL 421 Query: 187 GAIDDAIKAIDTQRAKLGATQNRLSHNISNSANTQANVADAKSRIVDVDFAKETSQMTKN 246 +ID A+ +D R+ LGA QNR I+N NT N+ A+SRI D D+A E S M+K Sbjct: 422 ASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYATEVSNMSKA 481 Query: 247 QVLQQTGSAMLAQANQLPQVALSLL 271 Q+LQQ G+++LAQANQ+PQ LSLL Sbjct: 482 QILQQAGTSVLAQANQVPQNVLSLL 506
>FLAGELLIN#Flagellin signature. Length = 507 Score = 144 bits (363), Expect = 7e-42 Identities = 101/270 (37%), Positives = 136/270 (50%), Gaps = 9/270 (3%) Query: 2 AITVNTNVTSMKAQKNLNASGNALATSMERLSSGLRINSAKDDAAGLAISNRLNSQVRGL 61 A +NTN S+ Q NLN S ++L++++ERLSSGLRINSAKDDAAG AI+NR S ++GL Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 DVGMRNANDGISVAQIAEGAMQEQTNMLQRMRDLSVQAVNGANSTSDKDAIQAEIDQLAL 121 RNANDGIS+AQ EGA+ E N LQR+R+LSVQA NG NS SD +IQ EI Q Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 EITAISNTTAFGDTKLLSGGFTAKNFQVGHQEGENISISISGTDASTLGVEGLLVSSDGA 181 EI +SN T F K+LS QVG +GE I+I + D +LG++G V+ Sbjct: 121 EIDRVSNQTQFNGVKVLSQDNQ-MKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKE 179 Query: 182 AS--------TSIGLIDTAIKTIDTQRAKLGATQNRLSHNISNSANTQSNVADAKSRIVD 233 A+ ++ DT + R + + + A D Sbjct: 180 ATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTD 239 Query: 234 VDFAKETSAMTKNQVLQQTGSAMLAQANQL 263 + K + A A + Sbjct: 240 DAENNTAVDLFKTTKSTAGTAEAKAIAGAI 269 Score = 87.4 bits (216), Expect = 1e-21 Identities = 57/265 (21%), Positives = 97/265 (36%) Query: 7 TNVTSMKAQKNLNASGNALATSMERLSSGLRINSAKDDAAGLAISNRLNSQVRGLDVGMR 66 N T++ K ++ + D G+ + + G Sbjct: 242 ENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGNGKVST 301 Query: 67 NANDGISVAQIAEGAMQEQTNMLQRMRDLSVQAVNGANSTSDKDAIQAEIDQLALEITAI 126 N +A+ ++ + N D ++ A Sbjct: 302 TINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSDLEAN 361 Query: 127 SNTTAFGDTKLLSGGFTAKNFQVGHQEGENISISISGTDASTLGVEGLLVSSDGAASTSI 186 + + +TA + + ++ + + + Sbjct: 362 NAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINEDAAAAKKSTANPL 421 Query: 187 GLIDTAIKTIDTQRAKLGATQNRLSHNISNSANTQSNVADAKSRIVDVDFAKETSAMTKN 246 ID+A+ +D R+ LGA QNR I+N NT +N+ A+SRI D D+A E S M+K Sbjct: 422 ASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYATEVSNMSKA 481 Query: 247 QVLQQTGSAMLAQANQLPQVALSLL 271 Q+LQQ G+++LAQANQ+PQ LSLL Sbjct: 482 QILQQAGTSVLAQANQVPQNVLSLL 506
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 39.9 bits (93), Expect = 2e-05 Identities = 15/35 (42%), Positives = 22/35 (62%) Query: 2 SFNIALSGISAAQKDLNTTANNIANANTIGFKESR 36 N A+SG++AAQ LNT +NNI++ N G+ Sbjct: 3 LINNAMSGLNAAQAALNTASNNISSYNVAGYTRQT 37 Score = 37.6 bits (87), Expect = 1e-04 Identities = 12/49 (24%), Positives = 25/49 (51%) Query: 405 SISSSALEQSNIDLTTELVDLISAQRNFQANSRTLEVNNTLQQTVLQIR 453 +S+ S ++L E +L Q+ + AN++ L+ N + ++ IR Sbjct: 498 QLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR 546
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 33.0 bits (75), Expect = 3e-04 Identities = 9/38 (23%), Positives = 18/38 (47%) Query: 99 NVNVMEEMADMISASRSYQMNVQVAEAAKSMLQQTLGM 136 VN+ EE ++ + Y N QV + A ++ + + Sbjct: 508 GVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545 Score = 29.9 bits (67), Expect = 0.003 Identities = 16/67 (23%), Positives = 29/67 (43%), Gaps = 6/67 (8%) Query: 5 SIFDVAGSGMSAQSVRLNTTASNIANADSVSSSVDKTYRSRHPIFEAEMAKAQSQQQASQ 64 S+ + A SG++A LNT ++NI++ + Y + I + + Sbjct: 2 SLINNAMSGLNAAQAALNTASNNISSYN------VAGYTRQTTIMAQANSTLGAGGWVGN 55 Query: 65 GVAVKGI 71 GV V G+ Sbjct: 56 GVYVSGV 62
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 61.4 bits (149), Expect = 1e-12 Identities = 23/128 (17%), Positives = 52/128 (40%), Gaps = 12/128 (9%) Query: 180 HIMVIDDSAVARKQIIRSLESLNLQIDTAKDGREALDKLKEIAKEMDNVADEIPLIISDI 239 I+V DD A R + ++L + + + A + L+++D+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIA---------AGDGDLVVTDV 55 Query: 240 EMPEMDGYTLTAEIRDDPKLKHIKVVLHTSLSGVFNQAMVQKVGANDFIAK-FNPDELAA 298 MP+ + + L I+ + V++ ++ + + GA D++ K F+ EL Sbjct: 56 VMPDENAFDLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIG 113 Query: 299 AVNKHLSL 306 + + L+ Sbjct: 114 IIGRALAE 121
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 189 bits (482), Expect = 4e-60 Identities = 75/332 (22%), Positives = 132/332 (39%), Gaps = 29/332 (8%) Query: 3 KVLVTGADGFIGSHLVEMLVAQGYQVRALSQYNSFNYWGWLEN----IDCLDEVEVICGD 58 K LVTGA GFIG H+ + L+ G+QV + N + Y L+ + + D Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDY-YDVSLKQARLELLAQPGFQFHKID 60 Query: 59 IRDPHFCKHLCKD--IDVIYHLAALIAIPYSYIAPDSYLDTNAKGTLNICQAALENNVSR 116 + D L + ++ +A+ YS P +Y D+N G LNI + N + Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 117 VIHTSTSEVYGTAKYVPIDEQHPL-QPQSPYSASKMAADAMAMSFHNSFELPLTIARPFN 175 +++ S+S VYG + +P + P S Y+A+K A + MA ++ + + LP T R F Sbjct: 121 LLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFFT 180 Query: 176 TYGPRQSARAVIPTIISQIAAGATQIKLGDISPTRDFNYVLDTCRGFIALA---AHDNCI 232 YGP + + G + RDF Y+ D I L H + Sbjct: 181 VYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHADTQ 240 Query: 233 --------------GETLNISSNYEISIEDTLNIIKQNMHSDVEFITDDARLRPQQSEVF 278 NI ++ + + D + ++ + + + Q +V Sbjct: 241 WTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLP----LQPGDVL 296 Query: 279 RLWGDNSKIKTLTGYQPQFDIHIGLKETITWF 310 D + + G+ P+ + G+K + W+ Sbjct: 297 ETSADTKALYEVIGFTPETTVKDGVKNFVNWY 328
>SALSPVBPROT#Salmonella virulence plasmid 65kDa B protein signature. Length = 591 Score = 31.3 bits (70), Expect = 0.016 Identities = 24/89 (26%), Positives = 45/89 (50%), Gaps = 12/89 (13%) Query: 604 SEILKKDTSVIAILIDSALMQSTPAEWLGKLREQLAWSGTPVLFLIPPNQNETKILLNKF 663 S++LK+ T++ I+ID A M ++P + AW +L + ++ +IL + Sbjct: 481 SDVLKEYTTIGNIIIDKAFMSTSPDK---------AWINDTILNIYLEKGHKGRILGDV- 530 Query: 664 HAHAMEYDENMTPPTEIVNKLQSILTKGT 692 AH E + PP + K++SI+ G+ Sbjct: 531 -AHFKGEAEMLFPPNTKL-KIESIVNCGS 557
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 45.6 bits (108), Expect = 4e-08 Identities = 28/98 (28%), Positives = 43/98 (43%), Gaps = 5/98 (5%) Query: 7 RKNNNRGFNLLEIMVVVAIIGILAVVAVPLYKDYIIRAQVTEAFVFADAERIKVIEKRIE 66 + RGF LLEIMVV+ IIG+LA + VP +A +A I +E ++ Sbjct: 3 ATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKA-----VSDIVALENALD 57 Query: 67 STNVDIATFSEPKVHMTSLMWVPVINNQPVENSVIGYI 104 +D + + SL+ P + + GYI Sbjct: 58 MYKLDNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYI 95
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 29.5 bits (66), Expect = 0.007 Identities = 19/78 (24%), Positives = 37/78 (47%), Gaps = 8/78 (10%) Query: 142 IVIISVFIVIVTSFFYAKQDKVIAPESALAQQLMVVVNGIEKYRLENNKTP---EKLSDL 198 IVII V +V ++K + A++ ++ + N ++ Y+L+N+ P + L L Sbjct: 19 IVIIGVLASLVVPNLMGNKEKADK-QKAVSD-IVALENALDMYKLDNHHYPTTNQGLESL 76 Query: 199 LEFPR---EAVEWRIDQY 213 +E P A + + Y Sbjct: 77 VEAPTLPPLAANYNKEGY 94
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 29.5 bits (66), Expect = 0.010 Identities = 13/71 (18%), Positives = 21/71 (29%) Query: 69 NEQRARFHYDRGVIYDSVGLRLLARIDFMQALKLQPDLADAYNFLGIYYTQEGEYASAYE 128 + +RF G ++G LA + + Q+GE A A Sbjct: 66 DHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAES 125 Query: 129 AFDGVLELAPN 139 EL + Sbjct: 126 GLFLAQELIAD 136
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 72.2 bits (177), Expect = 5e-15 Identities = 51/202 (25%), Positives = 78/202 (38%), Gaps = 30/202 (14%) Query: 387 IMGHVDHGKTSLLDYIRRAKVAAGEAG------------------GITQHIGAYHVETEN 428 ++ HVD GKT+L + + A E G GIT G + EN Sbjct: 8 VLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWEN 67 Query: 429 GMITFLDTPGHAAFTAMRARGAKATDIVVLVVAADDGVMPQTIEAIQHAKAGNVPLIVAV 488 + +DTPGH F A R D +L+++A DGV QT + +P I + Sbjct: 68 TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFI 127 Query: 489 NKMDKPEADIDRV----KSELSQHGVMS-------EDWGGDNMFAFVSAKTGEGVDELLE 537 NK+D+ D+ V K +LS V+ + + EG D+LLE Sbjct: 128 NKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGNDDLLE 187 Query: 538 GILLQAEVLELKAVRDGMAAGV 559 + + LE + + Sbjct: 188 K-YMSGKSLEALELEQEESIRF 208
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 29.5 bits (66), Expect = 0.025 Identities = 10/64 (15%), Positives = 23/64 (35%), Gaps = 8/64 (12%) Query: 6 QLKAENKALKERLIQLEQQRQNEIDELRSMIRENETMQQQSRQNADHYTEVIACQNQGGD 65 K ++ LK + L++ N I+ + ++ + D + G+ Sbjct: 289 YAKDKSDRLKSKSSDLQKIVMNNINRCTKKDKILNNTLKKCE-DKDIF-------KLYGE 340 Query: 66 MLNA 69 +L A Sbjct: 341 LLTA 344
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 145 bits (366), Expect = 1e-45 Identities = 76/203 (37%), Positives = 116/203 (57%), Gaps = 5/203 (2%) Query: 6 STVEQQASYGVGRQMGEQLAANSFDGVDIPAVQAGLADAFAGLESAVS---MQDLQVAFT 62 +T + + SY +G +G+ D ++ + G+ D +G + ++ M+D+ F Sbjct: 28 TTDKDKLSYSIGADLGKNFKNQGID-INPDVLAKGMQDGMSGAQLILTEEQMKDVLSKFQ 86 Query: 63 -EISGRIQAAQEQAAAAASAEGDAFLAENAKRDGVTVTDSGLQFEVLVQGDGATPTYEDT 121 ++ + A + A A+GDAFL+ N + G+ V SGLQ++++ G GA P DT Sbjct: 87 KDLMAKRSAEFNKKAEENKAKGDAFLSANKSKPGIVVLPSGLQYKIIDAGTGAKPGKSDT 146 Query: 122 VRTHYHGSFINGDVFDSSVVRGQPAEFPVSGVIAGWTEALQLMPVGTKLKLFVPHHLAYG 181 V Y G+ I+G VFDS+ G+PA F VS VI GWTEALQLMP G+ ++FVP LAYG Sbjct: 147 VTVEYTGTLIDGTVFDSTEKAGKPATFQVSQVIPGWTEALQLMPAGSTWEVFVPADLAYG 206 Query: 182 ERGAGASIPPYSTLVFEVELLDI 204 R G I P TL+F++ L+ + Sbjct: 207 PRSVGGPIGPNETLIFKIHLISV 229
>LUXSPROTEIN#Bacterial autoinducer-2 (AI-2) production protein LuxS signature. Length = 171 Score = 271 bits (695), Expect = 6e-97 Identities = 131/168 (77%), Positives = 150/168 (89%) Query: 2 PLLDSFTVDHTRMNAPAVRVAKHMSTPKGDAITVFDLRFCAPNKDILSERGIHTLEHLFA 61 PLLDSFTVDHTRMNAPAVRVAK M TPKGD ITVFDLRF APNKDILSE+GIHTLEHL+A Sbjct: 1 PLLDSFTVDHTRMNAPAVRVAKTMQTPKGDTITVFDLRFTAPNKDILSEKGIHTLEHLYA 60 Query: 62 GFMRDHLNGSNVEIIDISPMGCRTGFYMSLIGEPTERQVADAWLAAMEDVLKVVEQSEIP 121 GFMR+HLNG +VEIIDISPMGCRTGFYMSLIG P+E+QVADAW+AAMEDVLKV Q++IP Sbjct: 61 GFMRNHLNGDSVEIIDISPMGCRTGFYMSLIGTPSEQQVADAWIAAMEDVLKVENQNKIP 120 Query: 122 ELNEYQCGTYEMHSLEQAQDIARNIIAAGVSVNRNDDLKLSDEILGNL 169 ELNEYQCGT MHSL++A+ IA+NI+ GV+VN+ND+L L + +L L Sbjct: 121 ELNEYQCGTAAMHSLDEAKQIAKNILEVGVAVNKNDELALPESMLREL 168
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 32.5 bits (73), Expect = 0.009 Identities = 34/166 (20%), Positives = 62/166 (37%), Gaps = 15/166 (9%) Query: 5 DDVAQLKAELAQLQSLHLSQQFS---LSRQLAEFSTKLDTLSQQIATEDASDTTVSMAAV 61 D A L A A L + + + + E T L+ + T D A Sbjct: 126 DVTASLSALFAMLPGFDNTPKVTDAPSTVLPTEKPTLFTKLTSEQLTTAQPDDAPGTPAQ 185 Query: 62 SMTAGAASIAAVVPATDNAPTLTYAIHTPILESAPVAPVPVEPNPWQQNAVQGDPWQRNT 121 +T A + + P+ A +P++ P+P P + WQ+ Sbjct: 186 PLTPLVAEAQSKA-EVISTPSPVTAAASPLITPHQTQPLPTVAAPVLSAPLGSHEWQQ-- 242 Query: 122 KNTSAEQVAKTEYQAQGQQLSDEVKLQ----ASVQVASQFDDLLSQ 163 + ++ ++ + QGQQ S E++L VQ++ + DD +Q Sbjct: 243 --SLSQHISL--FTRQGQQ-SAELRLHPQDLGEVQISLKVDDNQAQ 283
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 29.3 bits (65), Expect = 0.027 Identities = 18/67 (26%), Positives = 30/67 (44%), Gaps = 1/67 (1%) Query: 248 FEAISVRVPTINVTAIDLSVTLEKTVDIATVNQVLESA-ANGRFNGILGYTDEPLVSCDF 306 F + + + A++ S LE T T+ + L+ A NG L Y + + DF Sbjct: 522 FNGKDLNLVERRIAAVNPSDPLETTKPDMTLKEALKIAFGFNEPNGNLQYQGKDITEFDF 581 Query: 307 NHDPRSS 313 N D ++S Sbjct: 582 NFDQQTS 588
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 28.2 bits (63), Expect = 0.024 Identities = 10/30 (33%), Positives = 17/30 (56%) Query: 1 MKIVVVGASGTIGQAIVRLFHSTQHEVIQV 30 MK +V GA+G IG + + H+V+ + Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGI 30
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 83.3 bits (206), Expect = 1e-20 Identities = 31/131 (23%), Positives = 61/131 (46%), Gaps = 1/131 (0%) Query: 1 MQNPHILIVEDEAVTRNTLRSIFEAEGYVVTEANDGAEMHKAMQENKINLVVMDINLPGK 60 M IL+ +D+A R L GY V ++ A + + + +LVV D+ +P + Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 NGLLLARELREIN-NIGLIFLTGRDNEVDKILGLEIGADDYITKPFNPRELTIRARNLLT 119 N L +++ ++ ++ ++ ++ + I E GA DY+ KPF+ EL L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 120 RVNSAGAEVEE 130 +++E+ Sbjct: 121 EPKRRPSKLED 131
>SECETRNLCASE#Bacterial translocase SecE signature. Length = 127 Score = 25.2 bits (55), Expect = 0.047 Identities = 11/25 (44%), Positives = 15/25 (60%) Query: 2 QTMKLTFVTAGVVLVGSLLLNGCDG 26 +T+ T + A V V SL+L G DG Sbjct: 89 ETLHTTLIVAAVTAVMSLILWGLDG 113
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 53.9 bits (129), Expect = 3e-09 Identities = 56/320 (17%), Positives = 103/320 (32%), Gaps = 18/320 (5%) Query: 599 EYAASEQELRIRLSKAEEAHTSAQEMQAEAESQLVAINGELDNLSRELTFARTAYKNSRD 658 EL LS A+E + +E S++ + +L + L A Sbjct: 82 ALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSA 141 Query: 659 DLRRLFDEKRSEQDKINKALSERKAQAGQRLTQLDGELKQLKHQHELWLEEQKEQALEAR 718 ++ L EK + KA G K + E E ++ LE Sbjct: 142 KIKTLEAEK---AALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKA 198 Query: 719 MEKQAYWQEVIGALDNQLGQIKATIEGRRESAKIELKACETWYKNELKSRGVDEENILKL 778 +E + A L KA + R+ + L+ + + E L Sbjct: 199 LEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAAL 258 Query: 779 KQQIRELETKISRAEQRRSDVLRFDDWYQHTWLMRKPKLQTQLADVKR----------AV 828 + + ELE + A + T K L+ + AD++ ++ Sbjct: 259 EARQAELEKALEGAMNFSTADSA----KIKTLEAEKAALEAEKADLEHQSQVLNANRQSL 314 Query: 829 SEIDQQLKAKTLDVKTRRQQLETERKASDAAQVEASENLTKLRAVMRKLAELKLPTNNEE 888 + ++ Q+LE + K S+A++ +L R ++L E + E+ Sbjct: 315 RRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQL-EAEHQKLEEQ 373 Query: 889 AQGSLGERLRQGEDLLLKRD 908 + S R DL R+ Sbjct: 374 NKISEASRQSLRRDLDASRE 393 Score = 33.5 bits (76), Expect = 0.006 Identities = 48/347 (13%), Positives = 114/347 (32%), Gaps = 28/347 (8%) Query: 360 WRTDVENLSERHKLQTEKHQDIEAAYNARRSKIGEQLNRELEGLHADQDKQREARDKQRE 419 + + + K+ D+ A + ++L EL + + R + Sbjct: 55 VQERADKFEIENNTLKLKNSDLSFNNKALKDHN-DELTEELSNA------KEKLRKNDKS 107 Query: 420 VARTDIDALELQWRNQMDAGKASFSEQEYQFKLTAAELKLRVDGVTYTEEEKLSLAIFDE 479 ++ EL+ R D KA + +A L + + ++ Sbjct: 108 LSEKASKIQELEARKA-DLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADL----EK 162 Query: 480 RIHRADEEQESCNAKVERLSSDERKLRAKRDQANEALRIATLRVNERQTALDELHHMLFP 539 + A + +AK++ L +++ L A++ + +AL A + L Sbjct: 163 ALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAA 222 Query: 540 QSHTL--LEFLRKEAQGWEQSLGKVIAPELLHRTDLHPSLVSESSEAFFGVHLDLKAIDV 597 + LE + A + + I + L + Sbjct: 223 LAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKA-------------L 269 Query: 598 PEYAASEQELRIRLSKAEEAHTSAQEMQAEAESQLVAINGELDNLSRELTFARTAYKNSR 657 ++ E + + +A+ E Q +N +L R+L +R A K Sbjct: 270 EGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLE 329 Query: 658 DDLRRLFDEKRSEQDKINKALSERKAQAGQRLTQLDGELKQLKHQHE 704 + ++L ++ + + ++L + + QL+ E ++L+ Q++ Sbjct: 330 AEHQKLEEQNKI-SEASRQSLRRDLDASREAKKQLEAEHQKLEEQNK 375
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.1 bits (221), Expect = 5e-23 Identities = 27/118 (22%), Positives = 48/118 (40%) Query: 7 VYLIDDDDSVRRSLRFMLESYGLKITDFDSAEAFFTAVDLTLPGCALVDVRMPGLSGPQL 66 + + DDD ++R L L G + +A + + + DV MP + L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 67 HLELVSKNSPLAVIYLTGHGDVPMAVEALKLGAVDFFQKPADGAKLAEAVVKALEHAK 124 + L V+ ++ A++A + GA D+ KP D +L + +AL K Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 130 bits (328), Expect = 7e-35 Identities = 90/421 (21%), Positives = 176/421 (41%), Gaps = 19/421 (4%) Query: 25 TDYERGSRRSWIAVFGGLIGAFMAILDIQITNASMKEIQGSLGATLEEGSWISTAYLVAE 84 T Y + + R + I +F ++L+ + N S+ +I +W++TA+++ Sbjct: 3 TSYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTF 62 Query: 85 MIAIPLSGWLSTGLSVRRYLLWTTAAFIFASVLCSMAWN-LEAMIAFRALQGFFGGALIP 143 I + G LS L ++R LL+ F SV+ + + +I R +QG A Sbjct: 63 SIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPA 122 Query: 144 LAFRLILEFLPDNKRAVGMALFGVTATFAPSIGPTLGGWLTEQFSWHYLFYINVPPGLLV 203 L ++ ++P R L G +GP +GG + W YL +P ++ Sbjct: 123 LVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLL--LIPMITII 180 Query: 204 MAMLAYGLEKQSVVWDKLKNVDLAGIVTMALGMGCLEVVLEEGNRKDWFGSELIRNLAII 263 L K+ V + D+ GI+ M++G+ + F + + I+ Sbjct: 181 TVPFLMKLLKKEVRIKG--HFDIKGIILMSVGIVFFML----------FTTSYSISFLIV 228 Query: 264 AVVNLVLFVWIQLRRKEPLVNLRLLGKRDFVLSTVAYFLLGMALFGAIYLIPLYLSQVHD 323 +V++ ++FV + +P V+ L F++ + ++ + G + ++P + VH Sbjct: 229 SVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQ 288 Query: 324 YTPLEIGGVIMWMGFPQLLVL-PLVPKLMERFDSRYLAAFGFLMFAISYYMNSQMTADYA 382 + EIG VI++ G +++ + L++R Y+ G ++S+ S + Sbjct: 289 LSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFL--LET 346 Query: 383 GPQMIASQVVRALG-QPFILVPIGMLATMHLKPHENASASTVLNVMRNLGGAFGIALVAT 441 + +V LG F I + + LK E + ++LN L GIA+V Sbjct: 347 TSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGG 406 Query: 442 L 442 L Sbjct: 407 L 407
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 98.7 bits (246), Expect = 6e-25 Identities = 42/294 (14%), Positives = 96/294 (32%), Gaps = 28/294 (9%) Query: 71 LAQLEDNQFSAKVSQAEASLASSKADLQTLAAKVELQRALITQASAGVVAAESDKIRAQQ 130 + + + S + ++ + ++ +RA A + E+ + Sbjct: 176 FQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKS 235 Query: 131 QLSRSKKLKVSNYSSQDDVDQLQAGFDSAAARLDEAKA--------VLVAKQRELAVFN- 181 +L L ++ V + + + A L K+ +L AK+ V Sbjct: 236 RLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQL 295 Query: 182 ------AQLDQAGSVVEQADATLELAKIQLNDTRVTAPFSGVIGKRGAM-VGQYVQPGQA 234 +L Q + L + + + + AP S + + G V + Sbjct: 296 FKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAET 355 Query: 235 LYSLVPDGAV-WITANFKETQIQHMQPGQSVQVSLDAFPDKTFIGVIDSLSPASGAKFSL 293 L +VP+ +TA + I + GQ+ + ++AFP + G + K Sbjct: 356 LMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRY-GYLV-------GKVKN 407 Query: 294 LPAENATGNFTKIVQRIPVRIRLDLSEAEAHML---PGLSAVVKVDTASGTAIS 344 + + +V + + I + + G++ ++ T + IS Sbjct: 408 INLDAIEDQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGMRSVIS 461
>MECHCHANNEL#Bacterial mechano-sensitive ion channel signature. Length = 136 Score = 170 bits (431), Expect = 8e-58 Identities = 85/136 (62%), Positives = 110/136 (80%), Gaps = 1/136 (0%) Query: 1 MSLIKEFKAFASRGNVIDMAVGIIIGAAFGKIVSSFVADIIMPPIGIILGGVNFSDLSIV 60 MS+IKEF+ FA RGNV+D+AVG+IIGAAFGKIVSS VADIIMPP+G+++GG++F ++ Sbjct: 1 MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60 Query: 61 LQAAQGDAPSVVIAYGKFIQTIIDFTIIAFAIFMGVKAINRLKRKEEVAPKAPAAPTKDQ 120 L+ AQGD P+VV+ YG FIQ + DF I+AFAIFM +K IN+L RK+E P A APTK++ Sbjct: 61 LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKE-EPAAAPAPTKEE 119 Query: 121 ELLSEIRDLLKAQQEK 136 LL+EIRDLLK Q + Sbjct: 120 VLLTEIRDLLKEQNNR 135
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 662 bits (1709), Expect = 0.0 Identities = 225/1075 (20%), Positives = 434/1075 (40%), Gaps = 73/1075 (6%) Query: 9 AIKNRLLVVLALLAMIVASVVMLPKLNLDAFPDVTNVQVTINTAAEGLAAEEVEKLISYP 68 I+ + + + +++A + + +L + +P + V+++ G A+ V+ ++ Sbjct: 5 FIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQV 64 Query: 69 VESAMYALPAVTEVRSLS-RTGLSIVTVVFAEGTDIYFARQQVFEQLQAAREMIPSGVGV 127 +E M + + + S S G +T+ F GTD A+ QV +LQ A ++P V Sbjct: 65 IEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQQ 124 Query: 128 PEIGPNTSGLGQIYQYILRAEPNSGIDAAELRSLNDYLVKLIMMPVGGVTEVLSFGGDVR 187 I S + ++ N G ++ VK + + GV +V FG Sbjct: 125 QGISVEKSSSSYLMVAGFVSD-NPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQ-Y 182 Query: 188 QYQVQVDPNKLRAYGLSMAQVTEALESNNRNAGGWFMDQGQE------QLVVRGYGMLPA 241 ++ +D + L Y L+ V L+ N + + Sbjct: 183 AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKN 242 Query: 242 GEEGLAAIAQIPLTEDK-GTPVRVGDIAQVDFGSEIRVGAVTMTRRDEAGNVQNLGEVVA 300 EE ++ L + G+ VR+ D+A+V+ G E + N Sbjct: 243 PEE----FGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARI----------NGKPAAG 288 Query: 301 GVVLKRMGANTKATIDDIGARVSLIEQALPDGVSFEVFYDQAELVDKAVTTVRDALLMAF 360 + GAN T I A+++ ++ P G+ YD V ++ V L A Sbjct: 289 LGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAI 348 Query: 361 VFIVVILALFLVNIRATLLVLLSIPVSIGLALMVMSYYGLSANLMSLGGLAVAIGMLVDG 420 + + +++ LFL N+RATL+ +++PV + +++ +G S N +++ G+ +AIG+LVD Sbjct: 349 MLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDD 408 Query: 421 SVVMVENIFKHLTQPDRRHLLEARTRADGEADPYHSDEDGGQQANMAVRIMLAAKEVCSP 480 ++V+VEN+ + + ED + M ++ Sbjct: 409 AIVVVENVERVMM------------------------EDKLPPKEATEKSM---SQIQGA 441 Query: 481 IFFATAIIIVVFAPLFALEGVEGKLFQPMAVSIILAMISALLVALIAVPALAVYLFK--- 537 + ++ VF P+ G G +++ +++I+ AM ++LVALI PAL L K Sbjct: 442 LVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVS 501 Query: 538 -------RGVVLKQSVVLAPLDAAYRKLLTATLARPKVVMLSALLMFALSLLLLPRLGTE 590 G + Y + L +L L+ A ++L RL + Sbjct: 502 AEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSS 561 Query: 591 FVPELEEGTINLRVTLAPTASLGTSLAVAPKLEAILLEFPEVEYALSRIGAPELGGDPEP 650 F+PE ++G + L A+ + V ++ L+ + S + Sbjct: 562 FLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNEKANVE-SVFTVNGFSFSGQA 620 Query: 651 VSNIEVYIGLKPISEWQSASSRLE--LQRLMEEKLSVFPGLLLTFSQPIATRVDELLSGV 708 + ++ LKP E + E + R E + G ++ F+ P + EL + Sbjct: 621 QNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGFVIPFNMP---AIVELGTAT 677 Query: 709 KAQLA-IKIFGPDLAVLSERGQALTDLVAKIPGAV-DVSLEQVSGEAQLVVRPKRELLAR 766 I G L++ L + A+ P ++ V + AQ + +E Sbjct: 678 GFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQA 737 Query: 767 YGISVDQVMSLVSQGIGGASAGQVIDGNARYDINVRLAAEFRTSPDAIKDLLLSGTNGAT 826 G+S+ + +S +GG ID + V+ A+FR P+ + L + NG Sbjct: 738 LGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEM 797 Query: 827 VRLGEVASVEVEMAPPNIRRDDVQRRVVVQANVA-GRDMGSVVKDIYALVPQADLPAGYT 885 V + P + R + + +Q A G G + + L + LPAG Sbjct: 798 VPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASK--LPAGIG 855 Query: 886 VIIGGQYENQQRAQQKLMLVVPISIALIALLLYFSFGSFKQVLLIMANVPLALIGGIVAL 945 G ++ + + +V IS ++ L L + S+ + +M VPL ++G ++A Sbjct: 856 YDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAA 915 Query: 946 YVSGTYLSVPSSIGFITLFGVAVLNGVVLVDSINQ-RRQSGEALYDCVYEGTVGRLRPVL 1004 + V +G +T G++ N +++V+ + G+ + + RLRP+L Sbjct: 916 TLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPIL 975 Query: 1005 MTALTSALGLIPILLSSGVGSEIQKPLAVVIIGGLFSSTALTLLVLPTLYRWLYR 1059 MT+L LG++P+ +S+G GS Q + + ++GG+ S+T L + +P + + R Sbjct: 976 MTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRR 1030 Score = 113 bits (284), Expect = 2e-27 Identities = 81/544 (14%), Positives = 185/544 (34%), Gaps = 61/544 (11%) Query: 10 IKNRLLVVLALLAMIVASVVMLPKLNLDAFPDVTNVQVTIN-TAAEGLAAEEVEKLI--- 65 + + +L ++ VV+ +L P+ G E +K++ Sbjct: 534 LGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQV 593 Query: 66 -SYPVESAMYALPAVTEVRSLSRTGLS----IVTVVFAEGTDIYFARQQVFEQLQAAREM 120 Y +++ + +V V S +G + + V + + A+ Sbjct: 594 TDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKME 653 Query: 121 ---IPSGVGVPEIGPNTSGLGQIYQYILRAEPNSGIDAAELRSLNDYLVKLIMMPVGGVT 177 I G +P P LG + +G+ L + L+ + + Sbjct: 654 LGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLV 713 Query: 178 EV-LSFGGDVRQYQVQVDPNKLRAYGLSMAQVTEALES--NNRNAGGWFMDQGQEQLVVR 234 V + D Q++++VD K +A G+S++ + + + + + ++L V+ Sbjct: 714 SVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQ 773 Query: 235 GYGMLPAGEEGLAAIAQIPLTEDKGTPVRVGDIAQVDFGSEIRVGAVTMTRRDEAGNVQN 294 + ++ + G V + G+ + R + +++ Sbjct: 774 AD---AKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVY----GSPRLERYNGLPSMEI 826 Query: 295 LGEVVAGVVLKRMGANTKATIDDIGARVSLIEQALPDGVSFEVFYDQAELVDKAVTTVRD 354 GE G D A + + LP G+ ++ + + + Sbjct: 827 QGEAAPGTSS-----------GDAMALMENLASKLPAGIGYD-WTGMSYQERLSGNQAPA 874 Query: 355 ALLMAFVFIVVILALFLVNIRATLLVLLSIPVSIGLALMVMSYYGLSANLMSLGGLAVAI 414 + ++FV + + LA + + V+L +P+ I L+ + + ++ + GL I Sbjct: 875 LVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTI 934 Query: 415 GMLVDGSVVMVENIFKHLTQPDRRHLLEARTRADGEADPYHSDEDGGQQANMAVRIMLAA 474 G+ ++++VE + L+E + EA ++A Sbjct: 935 GLSAKNAILIVEFA---------KDLMEKEGKGVVEA------------------TLMAV 967 Query: 475 KEVCSPIFFATAIIIVVFAPLFALEGVEGKLFQPMAVSIILAMISALLVALIAVPALAVY 534 + PI + I+ PL G + + ++ M+SA L+A+ VP V Sbjct: 968 RMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVV 1027 Query: 535 LFKR 538 + + Sbjct: 1028 IRRC 1031 Score = 102 bits (257), Expect = 2e-24 Identities = 89/515 (17%), Positives = 190/515 (36%), Gaps = 36/515 (6%) Query: 565 RPKVVMLSALLMFALSLLLLPRLGTEFVPELEEGTINLRVTLAPTASLGT-SLAVAPKLE 623 RP + A+++ L + +L P + +++ P A T V +E Sbjct: 8 RPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSAN-YPGADAQTVQDTVTQVIE 66 Query: 624 AILLEFPEVEYALSRIGAPELGGDPEPVSNIEVYIGLKPISEWQSASSRLELQRLMEEKL 683 + + Y S + ++ + + + ++ A Q ++ KL Sbjct: 67 QNMNGIDNLMYMSST---------SDSAGSVTITLTFQSGTDPDIA------QVQVQNKL 111 Query: 684 SVFPGLLLTFSQPIATRVDELLSGVKAQLAIKIFGPDLAVLSERGQALT---DLVAKIPG 740 + LL Q V++ S P + D ++++ G Sbjct: 112 QLATPLLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNG 171 Query: 741 AVDVSLEQVSGEAQLVVRPKRELLARYGISVDQVMSLVSQGIGGASAGQVIDGNA----R 796 DV L + + + +LL +Y ++ V++ + +AGQ+ A + Sbjct: 172 VGDVQL--FGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQ 229 Query: 797 YDINVRLAAEFRTSPDAIKDLLLSGTNGATVRLGEVASVEVEMAPPNIR-RDDVQRRVVV 855 + ++ F+ + K L ++G+ VRL +VA VE+ N+ R + + + Sbjct: 230 LNASIIAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGL 289 Query: 856 QANVA-GRDMGSVVKDIYALVP--QADLPAGYTVIIGGQYENQQRAQQKLMLVVP---IS 909 +A G + K I A + Q P G V+ Y+ Q + VV + Sbjct: 290 GIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLY--PYDTTPFVQLSIHEVVKTLFEA 347 Query: 910 IALIALLLYFSFGSFKQVLLIMANVPLALIGGIVALYVSGTYLSVPSSIGFITLFGVAVL 969 I L+ L++Y + + L+ VP+ L+G L G ++ + G + G+ V Sbjct: 348 IMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVD 407 Query: 970 NGVVLVDSINQRRQS-GEALYDCVYEGTVGRLRPVLMTALTSALGLIPILLSSGVGSEIQ 1028 + +V+V+++ + + + ++ A+ + IP+ G I Sbjct: 408 DAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIY 467 Query: 1029 KPLAVVIIGGLFSSTALTLLVLPTLYRWLYRGDKR 1063 + ++ I+ + S + L++ P L L + Sbjct: 468 RQFSITIVSAMALSVLVALILTPALCATLLKPVSA 502
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 52.9 bits (127), Expect = 1e-09 Identities = 36/182 (19%), Positives = 64/182 (35%), Gaps = 22/182 (12%) Query: 126 RATATLVVDRDRTATLAPQLDARVLARHVVPGQEVKKGEPLLTLGGAAVAQAQADYINAA 185 R V++ R + L + +A+H V QE + +N Sbjct: 225 RYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQE----------------NKYVEAVNEL 268 Query: 186 AEWSRVKRMSEGAVSVSRRMQAQVDAELKRAILEAIKMTPTQIRALE----STPEAIGSY 241 + E + ++ V K IL+ ++ T I L E + Sbjct: 269 RVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQAS 328 Query: 242 QLLAPIDGRVQQ-DIAMLGQVFSAGTPLMQLT-DESYLWVEAQLTPTQTAHITVGSAALV 299 + AP+ +VQQ + G V + LM + ++ L V A + I VG A++ Sbjct: 329 VIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAII 388 Query: 300 QV 301 +V Sbjct: 389 KV 390 Score = 41.4 bits (97), Expect = 5e-06 Identities = 26/148 (17%), Positives = 55/148 (37%), Gaps = 5/148 (3%) Query: 118 IANLNLDIRATATLVVDRDRTATLAPQLDARVLARHVVPGQEVKKGEPLLTLGG----AA 173 + + + A L R+ + P ++ V V G+ V+KG+ LL L A Sbjct: 77 LGQVEIVATANGKLTHS-GRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEAD 135 Query: 174 VAQAQADYINAAAEWSRVKRMSEGAVSVSRRMQAQVDAELKRAILEAIKMTPTQIRALES 233 + Q+ + A E +R + +S D + + E + T + + Sbjct: 136 TLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQF 195 Query: 234 TPEAIGSYQLLAPIDGRVQQDIAMLGQV 261 + YQ +D + + + +L ++ Sbjct: 196 STWQNQKYQKELNLDKKRAERLTVLARI 223
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 27.9 bits (62), Expect = 0.015 Identities = 8/29 (27%), Positives = 13/29 (44%) Query: 120 IQAERDGVVSAIWAKDGDEVAFDQPLFTL 148 I+ + +V I K+G+ V L L Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKL 127
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 155 bits (394), Expect = 4e-49 Identities = 89/227 (39%), Positives = 128/227 (56%), Gaps = 9/227 (3%) Query: 21 ALFVSVTSFAAPSLKSDADKTSYSIGASIGNYISGQVYNQVELGSEVNIDLVVQGFVDAL 80 A+ ++ + A SL +D DK SYSIGA +G Q G ++N D++ +G D + Sbjct: 14 AMSTAMAATDATSLTTDKDKLSYSIGADLGKNFKNQ-------GIDINPDVLAKGMQDGM 66 Query: 81 KDKQ-QLTDEEVVTYLNQRAEELNAARKILAEKEMAETKKASADYLAQNAKQSNVKVTAS 139 Q LT+E++ L++ ++L A R K+ E K +L+ N + + V S Sbjct: 67 SGAQLILTEEQMKDVLSKFQKDLMAKRSAEFNKKAEENKAKGDAFLSANKSKPGIVVLPS 126 Query: 140 GLQYQVITQGSGQKPNPEDVVTVEYVGTLIDGTEFENTVGRKEHTRFALMTVIPGWEEGL 199 GLQY++I G+G KP D VTVEY GTLIDGT F++T + F + VIPGW E L Sbjct: 127 GLQYKIIDAGTGAKPGKSDTVTVEYTGTLIDGTVFDSTEKAGKPATFQVSQVIPGWTEAL 186 Query: 200 KLMPMGSKYRFVVPASLAYGTEAV-GIIPPESALIFEIELKNIEKPS 245 +LMP GS + VPA LAYG +V G I P LIF+I L +++K + Sbjct: 187 QLMPAGSTWEVFVPADLAYGPRSVGGPIGPNETLIFKIHLISVKKAA 233
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 28.7 bits (64), Expect = 0.002 Identities = 14/35 (40%), Positives = 16/35 (45%), Gaps = 1/35 (2%) Query: 2 MKTPLIMLVLCSTLLTSGCAELACSARTDVDPYEP 36 MK L L L +TLL GCA + DP E Sbjct: 1 MKLRLSALALGTTLLV-GCASSGTDQQGRSDPLEG 34
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 68.9 bits (168), Expect = 1e-17 Identities = 38/99 (38%), Positives = 51/99 (51%), Gaps = 2/99 (2%) Query: 9 LQVGEGKEAVKGALITTQYRGFLQDGTQFDSSYDRGQAFQCVIGTGRVIKGWDQGIMGMK 68 + G G + K +T +Y G L DGT FDS+ G+ +VI GW + + M Sbjct: 133 IDAGTGAKPGKSDTVTVEYTGTLIDGTVFDSTEKAGKP--ATFQVSQVIPGWTEALQLMP 190 Query: 69 VGGKRKLLVPAHLAYGERQVGAHIKPNSDLTFEIELLEV 107 G ++ VPA LAYG R VG I PN L F+I L+ V Sbjct: 191 AGSTWEVFVPADLAYGPRSVGGPIGPNETLIFKIHLISV 229
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 31.7 bits (72), Expect = 0.005 Identities = 60/359 (16%), Positives = 124/359 (34%), Gaps = 31/359 (8%) Query: 14 SLFVPVAGLSLFALASGYLMSLIPLSLTFFELSTSLAP---LLASIFYLGLLLGAPCIAP 70 L V ++ ++L A+ G +M ++P L S + +L +++ L AP + Sbjct: 6 PLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGA 65 Query: 71 IVTRIGHSKAFILFLNILLCSVVAMILIPKSGVWL--ASRLVAGFAVAGIFVVVESWLLM 128 + R G + +L +++ +V I+ +W+ R+VAG A V +++ Sbjct: 66 LSDRFG--RRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGA-TGAVAGAYIAD 122 Query: 129 ADTQKQRAKRLGLYMTALYG-GTAIGQLAIDYLGTKGNLPYLVVMGLLAAASLPALLVKR 187 +RA+ G +M+A +G G G + +G L + Sbjct: 123 ITDGDERARHFG-FMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLL 181 Query: 188 GQPQVSEQQSMSLSALKNLSQPAIMGCLVSGLLLGPIY-----------GLLPIYVALDM 236 + E++ + AL L+ + L ++ L I+ Sbjct: 182 PESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRF 241 Query: 237 GLDQQTGQFMALIIVGGMLVQPLVSYLSPIFNK-----SGLIVSFSLLGIAALLLLSQHS 291 D T + G+L + ++ L++ G +LL Sbjct: 242 HWDATTIGIS--LAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATR 299 Query: 292 SMTLIIGFLLLGASAFALYPIAISLACDNLPASQMVSVAQVMLLSY-SVGSVIGPLVAS 349 +LL + + A+ + Q L + S+ S++GPL+ + Sbjct: 300 GWMAFPIMVLLASGGIGM--PALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFT 356
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 28.9 bits (64), Expect = 0.027 Identities = 19/101 (18%), Positives = 38/101 (37%) Query: 158 VTSAITNSIKGPVEINSVQIENIDFSNAYEKSVEDRMRAEVEVQTQLQNLEKERVSAQIA 217 VT++ T + +I +Q SN + AE ++ NL ++ + Sbjct: 291 VTASETRINRINADITQIQKAISQVSNNRNAGIARVHEAEENLKKAQNNLLNSQIKDAVD 350 Query: 218 VTQAQAQADSQLARAKAEAESIRIKGDAEASAIKSRAEALA 258 T + Q ++ K + + ++ I + EALA Sbjct: 351 ATVSFYQTLTEKYGEKYSKMAQELADKSKGKKIGNVNEALA 391
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 73.2 bits (179), Expect = 2e-17 Identities = 48/184 (26%), Positives = 80/184 (43%), Gaps = 2/184 (1%) Query: 3 GLTGKVVIITGASEGIGRALAVAMARMGCQLVISARNETRLASLALEIANYGLPPFVFAA 62 G+ GK+ ITGA++GIG A+A +A G + N +L + + F A Sbjct: 5 GIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPA 64 Query: 63 DVSRAEQCEALIEATVAHYGHLDILINNAGMTMWSRFDELTQLSVLEDIMRVNYLGPAYL 122 DV + + + G +DIL+N AG+ L+ E VN G Sbjct: 65 DVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEW-EATFSVNSTGVFNA 123 Query: 123 THAALPHLKASK-GQVVVVASVAGLTGVPTRSGYAASKHAVIGFFDSLRIELADDNVAVT 181 + + ++ + G +V V S + + YA+SK A + F L +ELA+ N+ Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 182 VICP 185 ++ P Sbjct: 184 IVSP 187
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.0 bits (65), Expect = 0.036 Identities = 13/77 (16%), Positives = 32/77 (41%), Gaps = 6/77 (7%) Query: 81 FMLYQQMQQQLLVQDAKNIALQDQLQQALLQPNQRIGQLEQQQLNDAKT-----YQELTK 135 F +Q + Q + K A + A + + + ++E+ +L+D + Sbjct: 195 FSTWQNQKYQKELNLDKKRA-ERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHA 253 Query: 136 LAEDQNQLQDRINKLAQ 152 + E +N+ + +N+L Sbjct: 254 VLEQENKYVEAVNELRV 270
>CABNDNGRPT#NodO calcium binding signature. Length = 479 Score = 79.2 bits (195), Expect = 2e-16 Identities = 40/172 (23%), Positives = 64/172 (37%), Gaps = 6/172 (3%) Query: 6410 GSDTINGGNGDDILFGDAIN--FNGISGQGYVAIKDYVADQLGIAAVTDAQVHRYITEHA 6467 + T G+ + + + + A + ++ I + Sbjct: 260 ANMTTRTGDSVYGFNSNTDRDFYTATDSSKALIFSVWDAGGTDTFDFSGYSNNQRINLNE 319 Query: 6468 SDFDQSGASDKADVLIGGQGNDILYGQGGNDQLYGGNGNDLIFGGAGNDTIIGGLGNDKL 6527 F G + G + G GND L G + ++++ GGAGND + GG G D L Sbjct: 320 GSFSDVGGLKGNVSIAHGVTIENAIGGSGNDILVGNSADNILQGGAGNDVLYGGAGADTL 379 Query: 6528 TGGTGADTFVWQAG----ESGTDHITDFNIHEDKLDLRDLLQGENTNTLDSY 6575 GG G DTFV+ +G + D I DF DK+DL + + Sbjct: 380 YGGAGRDTFVYGSGQDSTVAAYDWIADFQKGIDKIDLSAFRNEGQLSFVQDQ 431 Score = 48.4 bits (115), Expect = 8e-07 Identities = 32/89 (35%), Positives = 41/89 (46%), Gaps = 3/89 (3%) Query: 5831 GDFTTAPFNTGTRTIDNTSGQDQLLGTGGNDHLVSANGGGDLLYGMDGDDILVGSDAVQG 5890 F + ++ R N + G GN + + G G+DILVG+ A Sbjct: 302 DTFDFSGYSNNQRINLNEGSFSDVGGLKGNVSIAHGVTI-ENAIGGSGNDILVGNSA--D 358 Query: 5891 DSLYGGTGNDVLVAGLGNDGLYGGAGTDI 5919 + L GG GNDVL G G D LYGGAG D Sbjct: 359 NILQGGAGNDVLYGGAGADTLYGGAGRDT 387 Score = 44.2 bits (104), Expect = 2e-05 Identities = 31/120 (25%), Positives = 46/120 (38%), Gaps = 3/120 (2%) Query: 5798 ADKPVVNVILTDNGIPLYSNFKTSGITTEQFRTGDFTTAPFNTGTRTIDNTSGQDQLLGT 5857 + K ++ + G + S G F+ G +I + + +G Sbjct: 287 SSKALIFSVWDAGGTDTFDFSGYSNNQRINLNEGSFSDVGGLKGNVSIAHGVTIENAIGG 346 Query: 5858 GGNDHLVSANGGGDLLYGMDGDDILVGSDAVQGDSLYGGTGNDVLVAGLGNDGLYGGAGT 5917 GND LV N ++L G G+D+L G D+LYGG G D V G G D Sbjct: 347 SGNDILV-GNSADNILQGGAGNDVLYGGAG--ADTLYGGAGRDTFVYGSGQDSTVAAYDW 403 Score = 34.6 bits (79), Expect = 0.014 Identities = 30/135 (22%), Positives = 45/135 (33%), Gaps = 25/135 (18%) Query: 5825 TEQFRTGDFTTAPFNTGTRTIDNTSGQDQLLGTGGNDHLVSANGGGDLLYGMDGDDILVG 5884 T G + AP I G + TG + + ++N D D L+ Sbjct: 234 TGADYNGHYGGAPMIDDIAAIQRLYGANMTTRTGDSVYGFNSNTDRDFYTATDSSKALIF 293 Query: 5885 SDAVQG-----------------------DSLYGGTGNDVLVAGLGNDGLYGGAGTDIAV 5921 S G + G GN + G+ + GG+G DI Sbjct: 294 SVWDAGGTDTFDFSGYSNNQRINLNEGSFSDVGGLKGNVSIAHGVTIENAIGGSGNDI-- 351 Query: 5922 LLGNRADYIIEKSTG 5936 L+GN AD I++ G Sbjct: 352 LVGNSADNILQGGAG 366
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 310 bits (796), Expect = e-103 Identities = 86/431 (19%), Positives = 193/431 (44%), Gaps = 11/431 (2%) Query: 29 RLIIWALAAMVVCFLLWAGFAKLDKVTTGTGKVIPSSQVQVIQSLDGGIMQELYVQEGEM 88 RL+ + + +V + + +++ V T GK+ S + + I+ ++ I++E+ V+EGE Sbjct: 58 RLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGES 117 Query: 89 VTKGQPLVRIDDTRFRSDYAQQEQEVFGLKTNAIRMRAELDSILISDMTSDWREQVLITK 148 V KG L+++ +D + + + + R + SI E + + Sbjct: 118 VRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSI----------ELNKLPE 167 Query: 149 KALVFPENIIAAEPALVKRQQEEYNGRLDNLSNQLEILVRQIQQRQQEIDDLASKTTTLT 208 L V R + NQ + +++ E + ++ Sbjct: 168 LKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYE 227 Query: 209 TSMQLISRELELTRPLAKKGIVPEVELLKLERTVNDLQGELNSMRLLRPKVKAAMDEAIL 268 ++ L+ L K + + +L+ E + EL + ++++ + A Sbjct: 228 NLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKE 287 Query: 269 KRREAVFVYAADLRAQLNETQTRLSRMNEAQVGAQDKVSKAIITSPVNGTIKTTHINTLG 328 + + ++ ++ +L +T + + +++ ++I +PV+ ++ ++T G Sbjct: 288 EYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEG 347 Query: 329 GVVQPGVDIIEIVPSEDQLLIETKILPKDIAFLHPGLPAVVKITAYDFTRYGGLKGTVEH 388 GVV ++ IVP +D L + + KDI F++ G A++K+ A+ +TRYG L G V++ Sbjct: 348 GVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKN 407 Query: 389 ISADTSQDEEGNSYYLIRVRTAESSLTKNDGTQMPIIPGMLTSVDVITGQRSILEYILNP 448 I+ D +D+ + + + E+ L+ +P+ GM + ++ TG RS++ Y+L+P Sbjct: 408 INLDAIEDQRLGLVFNVIISIEENCLST-GNKNIPLSSGMAVTAEIKTGMRSVISYLLSP 466 Query: 449 ILRAKDTALRE 459 + + +LRE Sbjct: 467 LEESVTESLRE 477
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 27.5 bits (61), Expect = 0.039 Identities = 14/42 (33%), Positives = 19/42 (45%), Gaps = 4/42 (9%) Query: 70 IGFTFCPDVCPTTLNKLAAAYPDLNKIAPLQVVFLSVDPKRD 111 IG++F +V P LN++ A Y L V LS D Sbjct: 122 IGYSFGAEVIPFVLNEMPARYRK----NVLGAVLLSPSQSSD 159
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 29.5 bits (66), Expect = 0.017 Identities = 28/105 (26%), Positives = 48/105 (45%), Gaps = 13/105 (12%) Query: 1 MVKRVLLALIGLMTFSAHAVVILQYH-HVSETTP-AATSVTPAQFREQMQFLAD-DGFKV 57 +++R+L L LM + ++ + + + P ++ +TPAQ R+Q L D F V Sbjct: 13 VIRRILFYL--LMLLFCQQLAMIFWRIGLPDNAPVSSVQITPAQARQQPVTLNDFTLFGV 70 Query: 58 IPLSQVVEAIKQKQ--DLPAKTVAITF------DDGYRSIATTAH 94 P A+ Q +LP T+ ++ DD RSIA + Sbjct: 71 SPEKNKAGALDASQMSNLPPSTLNLSLTGVMAGDDDSRSIAIISK 115
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 28.1 bits (62), Expect = 0.022 Identities = 25/156 (16%), Positives = 52/156 (33%), Gaps = 11/156 (7%) Query: 27 ADARQLLELEPESEPSLESLSQSKQTAPLPLGTLLDSEGKPINLPDQEQSSFEYSAPTLT 86 ++ + + + E ++ T + E K + + + S + Sbjct: 1034 SETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSG---S 1090 Query: 87 PTESSKTTKSTKATQSTKATKSKKLSRKQQLASREHVANDPNCRWLDKRMDQLEAQLGGK 146 T+ ++TT++ + K K+K + K Q + P + Q E Sbjct: 1091 ETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPA---- 1146 Query: 147 QDNAATHQADELSARQKEWQCLKCDAEGPAQNDHSN 182 ++N T E ++ D E PA+ SN Sbjct: 1147 RENDPTVNIKEPQSQTNT----TADTEQPAKETSSN 1178
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 44.1 bits (104), Expect = 7e-07 Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 5/51 (9%) Query: 284 LCILDTGVNICHPLLQ----PFINEVDQFSVNPDWSPSDDNGHGTGMAGLA 330 + +LDTG + HP L+ N D +P+ D NGHGT +AG Sbjct: 45 VAVLDTGCDADHPDLKARIIGGRNFTDDDEGDPE-IFKDYNGHGTHVAGTI 94
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 61.8 bits (150), Expect = 7e-13 Identities = 41/215 (19%), Positives = 87/215 (40%), Gaps = 31/215 (14%) Query: 77 TRYKATIAELNAKAESQKLAWELAKHKYKRRIGLTNDNLVSKETFDEAFINTELARTSYE 136 YK+ + ++ ++ S K ++L +K I +L +T+ Sbjct: 269 RVYKSQLEQIESEILSAKEEYQLVTQLFKNEI------------------LDKLRQTTDN 310 Query: 137 LAQ--AQLNTAKIDLARTQIHAPENGTLINLSLR-NGNYVSKGNSVFSLV-KQDSLYITG 192 + +L + + I AP + + L + G V+ ++ +V + D+L +T Sbjct: 311 IGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTA 370 Query: 193 YFEETKIPLVHIGQNADVSLMSGGQVLHGKVTSIGKAIANTNVTTNGQLLPQIGQTFNWV 252 + I +++GQNA + + + +G + GK N+ + ++G FN + Sbjct: 371 LVQNKDIGFINVGQNAIIKVEAFPYTRYGYLV--GKV---KNINLDAIEDQRLGLVFNVI 425 Query: 253 RLSQRIPVDIELDSIPKDIELSVGMTVSIQLQTDK 287 I + K+I LS GM V+ +++T Sbjct: 426 I---SIEENCLSTGN-KNIPLSSGMAVTAEIKTGM 456 Score = 48.3 bits (115), Expect = 2e-08 Identities = 24/155 (15%), Positives = 56/155 (36%), Gaps = 9/155 (5%) Query: 9 LTLIVVAVAGIAGHWIWSHYLYSPWTRDGRVRA--EIITIAPDVYGWVNQLNVKDNQIVN 66 + ++ IA + T +G++ I P V ++ VK+ + V Sbjct: 60 VAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVR 119 Query: 67 KGDVLFTVDDTRYKATIAELNAKAESQKLA---WELAKHKYKR----RIGLTNDNLVSKE 119 KGDVL + +A + + +L +++ + + L ++ Sbjct: 120 KGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNV 179 Query: 120 TFDEAFINTELARTSYELAQAQLNTAKIDLARTQI 154 + +E T L + + Q Q +++L + + Sbjct: 180 SEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRA 214
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 46.4 bits (110), Expect = 7e-08 Identities = 33/126 (26%), Positives = 51/126 (40%), Gaps = 16/126 (12%) Query: 116 KDTIFSLLEHGLL---------PIINENDAVTADKLKVGDNDNLSAMVAAAADADTLIIC 166 +TI L+E G++ P+I E+ + + V D D +A +AD +I Sbjct: 176 AETIKKLVERGVIVIASGGGGVPVILEDGEIKGVE-AVIDKDLAGEKLAEEVNADIFMIL 234 Query: 167 SDVNGLYTQNPHENPDAQLIKQVTEINAEIYAMAGGASSAVGTGGMRTKIQAAKKAISHG 226 +DVNG + Q +++V Y G G M K+ AA + I G Sbjct: 235 TDVNGAALY--YGTEKEQWLREVKVEELRKYYEEGH----FKAGSMGPKVLAAIRFIEWG 288 Query: 227 IETFII 232 E II Sbjct: 289 GERAII 294
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 50.2 bits (120), Expect = 6e-09 Identities = 27/145 (18%), Positives = 50/145 (34%), Gaps = 10/145 (6%) Query: 3 YLMIGLYLLCFAVHASAVPVTVALPQTGSTNELLTLSGSIKSARVARLSARTDGLVAKVL 62 Y ++G ++ F + V + G LT SG K + + +V +++ Sbjct: 62 YFIMGFLVIAFILSVLG-QVEIVATANGK----LTHSGRSKE-----IKPIENSIVKEII 111 Query: 63 VDAGSQVRAGQPLLALDDTLAVHQLAQRQADVMAAKTMLAEKQRLLTEAQTLSAQQLFPE 122 V G VR G LL L A + Q+ ++ A+ Q L + +L Sbjct: 112 VKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLP 171 Query: 123 TERAIRQAALTEAEANLQSLTAALA 147 E + + E + + Sbjct: 172 DEPYFQNVSEEEVLRLTSLIKEQFS 196 Score = 42.5 bits (100), Expect = 1e-06 Identities = 32/194 (16%), Positives = 63/194 (32%), Gaps = 19/194 (9%) Query: 86 QLAQRQADVMAAKTMLAEKQRLLTEAQTLSAQQLFPETERAIRQAALTEAEANLQSLTAA 145 + + ++ K+ L + + + A+ Q + + I L + N+ LT Sbjct: 260 KYVEAVNELRVYKSQLEQIESEILSAK-EEYQLVTQLFKNEILDK-LRQTTDNIGLLTLE 317 Query: 146 LAHQKEVVARHQLMAPFAGVISSKQTET-GEWVNVGTEIFTLV-SQEQLWLDIQVPQEMF 203 LA +E + AP + + + T G V + +V + L + V + Sbjct: 318 LAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDI 377 Query: 204 QSVATATHVDIAADMLPEQQFIGHVNALV-------PVSDHNARSFLVRLTIPEADGL-- 254 + + I + P G++ V F V ++I E Sbjct: 378 GFINVGQNAIIKVEAFP-YTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCLSTG 436 Query: 255 -----LMPGTSATA 263 L G + TA Sbjct: 437 NKNIPLSSGMAVTA 450
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 27.4 bits (61), Expect = 0.042 Identities = 13/28 (46%), Positives = 16/28 (57%), Gaps = 1/28 (3%) Query: 6 VIGLGRF-GVAVSRELIHLGHTVTGVDN 32 V G F G VS+ L+ GH V G+DN Sbjct: 5 VTGAAGFIGFHVSKRLLEAGHQVVGIDN 32
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 92.6 bits (230), Expect = 6e-24 Identities = 35/112 (31%), Positives = 60/112 (53%), Gaps = 1/112 (0%) Query: 4 KVLVVDDEAQIHTFMRISLEAEGFEYHGAASIASALAQYQAQRPHVLVLDLGLPDGDGIS 63 +LV DD+A I T + +L G++ ++ A+ A ++V D+ +PD + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 64 LLQTLRQHDK-VPVLILTARDQEEEKIRLLEAGANDYLSKPFGIRELIARIK 114 LL +++ +PVL+++A++ I+ E GA DYL KPF + ELI I Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>PF06580#Sensor histidine kinase Length = 349 Score = 202 bits (516), Expect = 2e-62 Identities = 60/205 (29%), Positives = 110/205 (53%), Gaps = 13/205 (6%) Query: 351 EQLQEMTRKAEFTALQSKINPHFLFNALNAISSLIRIRPQQARELIANLADYLRYNLAKG 410 ++ M ++A+ AL+++INPHF+FNALN I +LI P +ARE++ +L++ +RY+L Sbjct: 152 WKMASMAQEAQLMALKAQINPHFMFNALNNIRALILEDPTKAREMLTSLSELMRYSLRYS 211 Query: 411 D-ELIDIQEEVKQVRDYVAIEQARFGDKLEVVFDVDD--VHFCVPCLLLQPLVENAILHG 467 + + + +E+ V Y+ + +F D+L+ ++ + VP +L+Q LVEN I HG Sbjct: 212 NARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHG 271 Query: 468 IQPRSAPGRVTIEVKKLDSGIRVAVRDTGYGISQEVIDGVAAGRIESSSIGLMNVHQRVK 527 I G++ ++ K + + + V +TG ES+ GL NV +R++ Sbjct: 272 IAQLPQGGKILLKGTKDNGTVTLEVENTG--------SLALKNTKESTGTGLQNVRERLQ 323 Query: 528 LLYGE--GLQLKRLEPGTEVSFYLP 550 +LYG ++L + +P Sbjct: 324 MLYGTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 67.5 bits (165), Expect = 4e-15 Identities = 24/132 (18%), Positives = 59/132 (44%), Gaps = 6/132 (4%) Query: 3 KAIIVEDEYLAREELE-YLVKSHSEIDIVASFEDGLEAFKYLQDHEVDVVFLDIQIPSID 61 ++ +D+ R L L ++ ++ I ++ + + D+V D+ +P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRW---IAAGDGDLVVTDVVMPDEN 61 Query: 62 GLLLAKNLHKSTHPPHVVFVTAYKEF--AVEAFELEAFDYILKPYNEPRIISLLQKIELA 119 L + K+ V+ ++A F A++A E A+DY+ KP++ +I ++ + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 120 GRQAPKPQHEAA 131 ++ P + + Sbjct: 122 PKRRPSKLEDDS 133
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 34.8 bits (80), Expect = 6e-04 Identities = 54/278 (19%), Positives = 101/278 (36%), Gaps = 39/278 (14%) Query: 43 PVSQVAFVFGLL----SLSLAVASSMAGKLQERFGVRNVTLGAGLLLGLGFLLTAQASNL 98 + V +G+L +L + + G L +RFG R V L + + + + A A L Sbjct: 37 HSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFL 96 Query: 99 MMLYLCAGILVGFADGTGY--------LMTLSNCVKWFPERKGLISALAIGAYGLGSLGF 150 +LY+ I+ G TG + + F G +SA +G G + Sbjct: 97 WVLYI-GRIVAGITGATGAVAGAYIADITDGDERARHF----GFMSA----CFGFGMVAG 147 Query: 151 KYINVLLLENTGLETTFQLWGLIAMALVLCGGMLMKDA------PAQSAASQQAESRDFT 204 + L+ F + L G L+ ++ P + A S F Sbjct: 148 PVLGGLMGG-FSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLAS--FR 204 Query: 205 LAEAMRKPQYWMLALMFLSACMSG----LYVIGVAKDIGEKMVDLPVLVAANAVAVIAMA 260 A M ++A+ F+ + L+VI + + +AA + + Sbjct: 205 WARGMT-VVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGI----LH 259 Query: 261 NLSGRLVLGILSDKIPRIRVISLAQIITLVGMVLLLFV 298 +L+ ++ G ++ ++ R + L I G +LL F Sbjct: 260 SLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFA 297
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 110 bits (276), Expect = 3e-28 Identities = 85/430 (19%), Positives = 170/430 (39%), Gaps = 29/430 (6%) Query: 30 FLAAVDQTLLATATPAIVEDLGGLR-QASWITIGYMLAMAASVPIYGWLGDNFGRAKILM 88 F + +++ +L + P I D +W+ +ML + +YG L D G ++L+ Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 89 IAIVIFALGSIVSA-SAGTMDHMIAGRILQGMGGGGLMSLSQSLIGELVPIRQRARFQGY 147 I+I GS++ +I R +QG G +L ++ +P R + G Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 148 FAAMFTLASVGGPVIGGIVVHAYSWHWLFWANIPLA-MLAVWRLNGLHKHSVKPVRQGKF 206 ++ + GP IGG++ H W +L IP+ ++ V L L K V+ +G F Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHYIHWSYLL--LIPMITIITVPFLMKLLKKEVR--IKGHF 199 Query: 207 DLVGVVLFPTIITALLYWLSVAGQEFAWLSATSLGFAVFVVFGILGLLLWERRLASPFLP 266 D+ G++L I + + + F +S S F +FV R++ PF+ Sbjct: 200 DIKGIILMSVGIVFFMLFTTSYSISFLIVSVLS--FLIFVKH--------IRKVTDPFVD 249 Query: 267 LDLLAKKAVYMPLLTAALFAACLFAMIFFLPIYLQVGLHTNPAKTG-LLLLPMTFGIVTG 325 L + +L + + + +P ++ + A+ G +++ P T ++ Sbjct: 250 PGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIF 309 Query: 326 STIAGRLLSKDVAPKWLPTFGMGLAFIGLILISFVPPNANVIGGLGV-LVGIGLGTVMPS 384 I G L+ + P ++ G+ + + SF+ + + + V GL Sbjct: 310 GYIGGILVDR-RGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTV 368 Query: 385 VQLVVQSVSGKARLSQITAMVSLCRSMGAAIGTALFSVLLYSLLPLTGSELGIAAIKTLP 444 + +V S + ++++ + G A+ LL + + + LP Sbjct: 369 ISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLL---------SIPLLDQRLLP 419 Query: 445 TEVVHHAFQY 454 EV + Y Sbjct: 420 MEVDQSTYLY 429
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 60.6 bits (147), Expect = 3e-12 Identities = 68/370 (18%), Positives = 129/370 (34%), Gaps = 46/370 (12%) Query: 22 LMFFMFAMTSDAVGV-----IIPELISQFGLSMSQASAFHYMPMIFIAMSGLF---LGFL 73 L+ + + DAVG+ ++P L+ S + + + ++ M LG L Sbjct: 7 LIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGAL 66 Query: 74 ADKIGRKLTILLGLLLFALACFMFALGESFYYFLFLLAFVGTAIGVFKTGALGLIGDIST 133 +D+ GR+ +L+ L A+ + A F + L++ V G A I DI T Sbjct: 67 SDRFGRRPVLLVSLAGAAVDYAIMATA-PFLWVLYIGRIVAGITGATGAVAGAYIADI-T 124 Query: 134 SSKQHSSTMNTVEGYFGVGAMIGPAIVSYLLISGVSWKYLYFGAGC-----FCLVLCWL- 187 + + + FG G + GP + + G S +F A F L Sbjct: 125 DGDERARHFGFMSACFGFGMVAGPVLGGLM--GGFSPHAPFFAAAALNGLNFLTGCFLLP 182 Query: 188 ----AYRADYPQIKRSSTDAINLASTFKMMKNPYALGFSL-AIGLYVATEVAIYV----- 237 R + + + A ++ A+ F + +G A I+ Sbjct: 183 ESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFH 242 Query: 238 WMPTLLQSYQGDYTTLAAYALT-IFFTLRAGGRFLGGWVLDRFPWQQVMFWFSFAISACY 296 W T + +LAA+ + G R +M + Sbjct: 243 WDATTIG------ISLAAFGILHSLAQAMITGPVAARLGERRA----LMLGMIADGTGYI 292 Query: 297 LGSMI---YGIEAAVILLPLSGLFMSMMYPTLNSKGISCFPVDQHGSVAGVILFFTAVSA 353 L + + ++LL G+ M + S+ + ++ G + G + T++++ Sbjct: 293 LLAFATRGWMAFPIMVLLASGGIGMP-ALQAMLSRQVD---EERQGQLQGSLAALTSLTS 348 Query: 354 AVGPLLMGFV 363 VGPLL + Sbjct: 349 IVGPLLFTAI 358
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 33.0 bits (75), Expect = 0.005 Identities = 60/276 (21%), Positives = 101/276 (36%), Gaps = 67/276 (24%) Query: 411 DDTSVTLGYYNATQ-NIGMS----WMWNSYLMEVKGDNAALLDVVAADGTAYSDNGLYGY 465 D T + +G+ TQ N ++ W +N +G+ A +A G + D G + Y Sbjct: 53 DQTYMRVGFKGETQINDQLTGYGQWEYNVQANTTEGEGANSWTRLAFAGLKFGDYGSFDY 112 Query: 466 GVPYWGNCCQRNYDTDYTIKAPYLALASSFGDLSLDASVRYDSGDASG------------ 513 G RNY Y ++ + + FG S + Y +G A+G Sbjct: 113 G---------RNYGVLYDVEG-WTDMLPEFGGDSYTYADNYMTGRANGVATYRNTDFFGL 162 Query: 514 ----NYAGSVQSQVDMNLDGVISIPEQSVSSIDNANPQPVNYDWSYTSYSLGANYQFASD 569 N+A Q + + ++I + ++ D+ N D + + Y Sbjct: 163 VDGLNFALQYQGKNESQSADDVNIGTNNRNNGDDIRYD--NGD----GFGISTTYDIGMG 216 Query: 570 LAAFARLSHGGRANADRLLFGKVRADGSVAKEDAVDIVDQYELGVKYRYDDLSVFATAFY 629 +A A + R N +++ G A G A D + G+KY D +++ Y Sbjct: 217 FSAGAAYTTSDRTN-EQVNAGGTIAGGDKA--------DAWTAGLKY--DANNIYLATMY 265 Query: 630 SET-------------------EEQNFEATSQRFFD 646 SET + QNFE T+Q FD Sbjct: 266 SETRNMTPYGKTDKGYDGGVANKTQNFEVTAQYQFD 301
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 182 bits (462), Expect = 3e-58 Identities = 70/288 (24%), Positives = 138/288 (47%), Gaps = 36/288 (12%) Query: 17 KPLSRIVFWLGFIVIMLLAAQITWKL-VPTSSSASAWSPTPVSVNGKGAGQVDLAGLQQL 75 + RI+F+L ++ A I W++ +P ++ S+ TP + L Sbjct: 12 SVIRRILFYLLMLLFCQQLAMIFWRIGLPDNAPVSSVQITPAQARQQPVT------LNDF 65 Query: 76 GLFGKADATSDKPKVEAVETVTDAPKTTLSIQLTGVVASTADQKGLAIIESNGSQDTYSL 135 LFG + + ++A +++ P +TL++ LTGV+A D + +AII + Q + + Sbjct: 66 TLFGVSPEKNKAGALDA-SQMSNLPPSTLNLSLTGVMAGDDDSRSIAIISKDNEQFSRGV 124 Query: 136 GDKIKGTSASLKEVYADRIIITNAGRYETLMLDGLVYTSQSPANQQLQQAKSNKAGSAVS 195 +++ G +A + + DR+++ GRYE L L + Sbjct: 125 NEEVPGYNAKIVSIRPDRVVLQYQGRYEVLGLYSQEDSGSDGVPG--------------- 169 Query: 196 RVDQRNNADISQELAESRTELLADPSKITDYIAISPVRQGDSVAGYRLNPGKDANLFKQA 255 A ++++L + + ++DY++ SP+ + + GYRLNPG ++ F + Sbjct: 170 -------AQVNEQLQQR------ASTTMSDYVSFSPIMNDNKLQGYRLNPGPKSDSFYRV 216 Query: 256 GFKANDLAKSINGYDLTVMSQALEMMSQLSELTEVSIMVEREGQLVEI 303 G + ND+A ++NG DL QA + M +++++ ++ VER+GQ +I Sbjct: 217 GLQDNDMAVALNGLDLRDAEQAKKAMERMADVHNFTLTVERDGQRQDI 264
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 600 bits (1549), Expect = 0.0 Identities = 330/683 (48%), Positives = 449/683 (65%), Gaps = 37/683 (5%) Query: 6 IRRKLIAGIVAGAAMFSSQFAWSEQYAANFKGTDIQEFINIVGKNLNKTIIVDPTIRGKI 65 IR + ++ A +F A +E+++A+FKGTDIQEFIN V KNLNKT+I+DP++RG I Sbjct: 7 IRSFSLTLLIFAALLFRP--AAAEEFSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTI 64 Query: 66 NVRSYDLLNDEQYYQFFLNVLQVYGYAIVEMENNVIKVIKDKDAKTAAIRVANDAEPGIG 125 VRSYD+LN+EQYYQFFL+VL VYG+A++ M N V+KV++ KDAKTAA+ VA+DA PGIG Sbjct: 65 TVRSYDMLNEEQYYQFFLSVLDVYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIG 124 Query: 126 DEMVTRIVALYNTEAKQLAPLLRQLNDNAGGGNVVNYDPSNVLMLSGRAAVVNKLVEIVR 185 DE+VTR+V L N A+ LAPLLRQLNDNAG G+VV+Y+PSNVL+++GRAAV+ +L+ IV Sbjct: 125 DEVVTRVVPLTNVAARDLAPLLRQLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVE 184 Query: 186 RVDKQGDTSVQVVPLEFASAGEMVRIIDTLYRATANQSQMPGQAPKVVADERINAVVVSG 245 RVD GD SV VPL +ASA ++V+++ L + T+ + VVADER NAV+VSG Sbjct: 185 RVDNAGDRSVVTVPLSWASAADVVKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSG 244 Query: 246 DEKSRQRVVELIHRLDAEQASTGNTKVRYLRYAKAEDLVEVLTGFAQKLEGEKDPNAQAA 305 + SRQR++ +I +LD +QA+ GNTKV YL+YAKA DLVEVLTG + ++ EK A Sbjct: 245 EPNSRQRIIAMIKQLDRQQATQGNTKVIYLKYAKASDLVEVLTGISSTMQSEK--QAAKP 302 Query: 306 GGKRRNEINIMAHAETNALVISAEPDQMRTIESVINQLDIRRAQVLVEAIIVEVAEGDNV 365 I I AH +TNAL+++A PD M +E VI QLDIRR QVLVEAII EV + D + Sbjct: 303 VAALDKNIIIKAHGQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGL 362 Query: 366 GFGVQWASKSGLGTQFNNLGPTIGEIGAGIWQAQDVKASQTCTGSGDNQTCTDNPDTKGD 425 G+QWA+K+ TQF N G I AG + + G Sbjct: 363 NLGIQWANKNAGMTQFTNSGLPISTAIAG----------------------ANQYNKDGT 400 Query: 426 VT-LLAQALGKVNGMAWGVAMGDFGALIQAVSSDTNSNVLATPSITTLDNQEASFIVGDE 484 V+ LA AL NG+A G G++ L+ A+SS T +++LATPSI TLDN EA+F VG E Sbjct: 401 VSSSLASALSSFNGIAAGFYQGNWAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQE 460 Query: 485 VPILTGSTASSSNSNPFQTVERKEVGVKLKVVPQINEGNAVKLTIEQEVSGVNG-----N 539 VP+LTGS ++S N F TVERK VG+KLKV PQINEG++V L IEQEVS V + Sbjct: 461 VPVLTGSQ-TTSGDNIFNTVERKTVGIKLKVKPQINEGDSVLLEIEQEVSSVADAASSTS 519 Query: 540 TGVDISFATRRLTTTVMADSGQIVVLGGLINEEVQESIQKVPFLGDIPIIGHLFKSSSSK 599 + + +F TR + V+ SG+ VV+GGL+++ V ++ KVP LGDIP+IG LF+S+S K Sbjct: 520 SDLGATFNTRTVNNAVLVGSGETVVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKK 579 Query: 600 KTKKNLMIFIKPTIIRDGITMEGIAGRKYNYFRALQLEQ--QERGVNLMPNTKVPVLEEW 657 +K+NLM+FI+PT+IRD + +Y F Q +Q +E ++ + + Sbjct: 580 VSKRNLMLFIRPTVIRDRDEYRQASSGQYTAFNDAQSKQRGKENNDAMLNQDLLEIYP-- 637 Query: 658 NQSEYLPPEVNAILERYKEGKGL 680 Q +V+A ++ + G L Sbjct: 638 RQDTAAFRQVSAAIDAFNLGGNL 660
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 506 bits (1304), Expect = 0.0 Identities = 229/407 (56%), Positives = 304/407 (74%), Gaps = 1/407 (0%) Query: 1 MPAFEYKALDAKGKQLKGVIEADTARHARSQLRDQRMMPLEILPVSEKEAKAKSSSFSF- 59 M + Y+ALDA+GK+ +G EAD+AR AR LR++ ++PL + + K+ S+ S Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 60 FKRGISVAELALITRQIATLVAAGLPIEESLKAVGQQCEKDRLASMIMAVRSRVVEGYSL 119 K +S ++LAL+TRQ+ATLVAA +P+EE+L AV +Q EK L+ ++ AVRS+V+EG+SL Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 120 ADSLAEFPHIFDDLYRAMVASGEKSGHLEVVLNRLADYTERRQQLKSKLTQAMIYPAVLT 179 AD++ FP F+ LY AMVA+GE SGHL+ VLNRLADYTE+RQQ++S++ QAMIYP VLT Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 180 TVAIGVISILLAAVVPKVVGQFEHMGAELPASTRFLISASDFVQNYGVFVVIALVMLFAL 239 VAI V+SILL+ VVPKVV QF HM LP STR L+ SD V+ +G ++++AL+ F Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMA 240 Query: 240 FRRMLKSPAFRMKYDNFLLSMPVVGRVSKGLNTARFARTLSILSASSVPLLDGMRIASEV 299 FR ML+ R+ + LL +P++GR+++GLNTAR+ARTLSIL+AS+VPLL MRI+ +V Sbjct: 241 FRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 300 LQNVRVRAAVDDATARVREGTSLGAALTNTKLFPAMMLYMIASGEKSGQLEQMLERAADN 359 + N R + AT VREG SL AL T LFP MM +MIASGE+SG+L+ MLERAADN Sbjct: 301 MSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADN 360 Query: 360 QDREFEGNVNIALGVFEPMLVVSMACVVLFIVMAILQPILALNNLIS 406 QDREF + +ALG+FEP+LVVSMA VVLFIV+AILQPIL LN L+S Sbjct: 361 QDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLMS 407
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 229 bits (584), Expect = 6e-81 Identities = 97/144 (67%), Positives = 119/144 (82%) Query: 1 MQMNKKHQGFTLLEVMVVIVILGILASMVVPNLMGNKDKADQQKAVSDIVALENALDMYK 60 M+ K +GFTLLE+MVVIVI+G+LAS+VVPNLMGNK+KAD+QKAVSDIVALENALDMYK Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK 60 Query: 61 LDNGIYPTTEQGLEALVQKPTISPEPRNYREDGYVKRLPEDPWRNKYLLLSPGENGKLDI 120 LDN YPTT QGLE+LV+ PT+ P NY ++GY+KRLP DPW N Y+L++PGE+G D+ Sbjct: 61 LDNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDL 120 Query: 121 FTAGPDGQPGTEDDIGNWNLQNFQ 144 +AGPDG+ GTEDDI NW L + Sbjct: 121 LSAGPDGEMGTEDDITNWGLSKKK 144
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 86.2 bits (213), Expect = 1e-23 Identities = 44/171 (25%), Positives = 70/171 (40%), Gaps = 39/171 (22%) Query: 17 LRHAGFTLMEVMLVILLMGLTAAAVTMSIGNSGPQQALDRTARQFIAATEMVLDETVLSG 76 +R GFTL+E+ML++LLMG++A V ++ S A AR F A V + +G Sbjct: 1 MRQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQTLAR-FEAQLRFVQQRGLQTG 59 Query: 77 QFIGIVIEKTSYQFVFYKDG---------------KWEPLDKDRLLSEKQMEPGVVMNLV 121 QF G+ + +QF+ + +W PL R+ + Sbjct: 60 QFFGVSVHPDRWQFLVLEARDGADPAPADDGWSGYRWLPLRAGRVATSGS---------- 109 Query: 122 LDGLPLVQDDEEDDSWFEEPLIEPSADDKKKHPEPQVMLFPSGEMSAFELT 172 + G L + ++W P V++FP GEM+ F LT Sbjct: 110 IAGGKLNLAFAQGEAW-------------TPGDNPDVLIFPGGEMTPFRLT 147
>PilS_PF08805#PilS N terminal Length = 185 Score = 29.1 bits (65), Expect = 0.003 Identities = 11/32 (34%), Positives = 17/32 (53%) Query: 5 KGMTLLEVIVALAVFSIAAVSITKSLGEQMAN 36 KG TL+EV++ + V + A S K +N Sbjct: 26 KGATLMEVLLVVGVIVVLAASAYKLYSMVQSN 57
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 31.4 bits (71), Expect = 0.002 Identities = 16/41 (39%), Positives = 27/41 (65%), Gaps = 3/41 (7%) Query: 3 LKLTSVQRGFTLLEMLIAIAIFAMIGLASNAVLSTVLTNDE 43 ++ T QRGFTLLE+++ I I IG+ ++ V+ ++ N E Sbjct: 1 MRATDKQRGFTLLEIMVVIVI---IGVLASLVVPNLMGNKE 38
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 99.0 bits (246), Expect = 5e-27 Identities = 71/257 (27%), Positives = 112/257 (43%), Gaps = 16/257 (6%) Query: 6 IALITGASRGLGKNTALKLAAQGIDIILTYQTNAAAAAEVVAEIEWLGRKAVALPLDVSD 65 IA ITGA++G+G+ A LA+QG I N +VV+ ++ R A A P DV D Sbjct: 10 IAFITGAAQGIGEAVARTLASQGAHI-AAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 66 SGSFAEFATQVSTVLAHTWQRESFNYLINNAGIGIHVPMAETSIEQFDTLMNIHVKGPFF 125 S + E ++ + + L+N AG+ + S E+++ +++ G F Sbjct: 69 SAAIDEITARIER------EMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 126 LTQTLLPLLMD--GGSIVNISTGLTRFAIPGFGAYATMKGAVETMTKYWAKELGPRGIRV 183 ++++ +MD GSIV + + AYA+ K A TK EL IR Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 184 NVLAPGAIETDFGGGAVRDNEQMNQFLAQQTA-------LGRVGLPDDIGGAISALLSPA 236 N+++PG+ ETD D Q + L ++ P DI A+ L+S Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 237 AAWINAQRIEASGGMFL 253 A I + GG L Sbjct: 243 AGHITMHNLCVDGGATL 259
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 320 bits (822), Expect = e-104 Identities = 117/359 (32%), Positives = 191/359 (53%), Gaps = 29/359 (8%) Query: 296 RDPQLERAWQHANKVITKQIPLLVLGETGVGKEQFVKKLHAQSARRTEHLVAVNCAALPA 355 R ++ ++ +++ + L++ GE+G GKE + LH RR VA+N AA+P Sbjct: 142 RSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPR 201 Query: 356 ELVESELFGYQAGAFTGANRTGFIGKIRQAHGGFLFLDEIGEMPLAAQSRLLRVLQEREV 415 +L+ESELFG++ GAFTGA G+ QA GG LFLDEIG+MP+ AQ+RLLRVLQ+ E Sbjct: 202 DLIESELFGHEKGAFTGAQTRS-TGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEY 260 Query: 416 VPVGSNQSFKVDIQIIAATHMDLEQQVAQGLFRQDLFYRLNGLQVRLPALRERQ-DIERI 474 VG + D++I+AAT+ DL+Q + QGLFR+DL+YRLN + +RLP LR+R DI + Sbjct: 261 TTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDL 320 Query: 475 IH---KLHRKHRIAPQAICPELLGQLMLHDWPGNLRELDNLMQVACLMAEGDDTLTWQHL 531 + + K + + E L + H WPGN+REL+NL++ + D +T + + Sbjct: 321 VRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQ-DVITREII 379 Query: 532 PDYLAQKLACDLLKVDPLNAQLLNTLQLNEEQPLGEEVKIGQNSASHPLAGKVVSGKVTS 591 + L ++ ++ + + + V+ + A Sbjct: 380 ENELRSEIPDSPIEKAAARS---------GSLSISQAVE---ENMRQYFA---------- 417 Query: 592 GNTATLPTATAVQSDSLHEAIYSNVLQAYKASDGNVSQCAKRLGISRNALYRRLKQMGL 650 + + + L E Y +L A A+ GN + A LG++RN L ++++++G+ Sbjct: 418 -SFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGV 475
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 29.0 bits (65), Expect = 0.023 Identities = 13/28 (46%), Positives = 18/28 (64%), Gaps = 2/28 (7%) Query: 151 VLVTGASGGVGS-VAVTLLANAGYRVVA 177 LVTGA+G +G V+ LL G++VV Sbjct: 3 YLVTGAAGFIGFHVSKRLLEA-GHQVVG 29
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.6 bits (69), Expect = 0.015 Identities = 10/31 (32%), Positives = 18/31 (58%), Gaps = 1/31 (3%) Query: 39 KWDKEIEILIVGSGFSGLAAAIEATRKGAKD 69 K ++ +L++ S + AI+A+ KGA D Sbjct: 71 KARPDLPVLVM-SAQNTFMTAIKASEKGAYD 100
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 39.2 bits (91), Expect = 5e-06 Identities = 24/135 (17%), Positives = 56/135 (41%), Gaps = 9/135 (6%) Query: 4 WEQRTDYLVEVAQRCL--RGHQSFDLYRSHLVAASQISKGTIYNHFTTEADLVVAVACAQ 61 ++ ++++VA R +G S L + A+ +++G IY HF ++DL + Sbjct: 9 AQETRQHILDVALRLFSQQGVSSTSL--GEIAKAAGVTRGAIYWHFKDKSDLFSEIWELS 66 Query: 62 YQDWL-ISAKQDRQQYSDP---FECYLFHHCQRLHDVLAHKRFVIERVMPNQELLQQASE 117 + + + + DP L H + +R ++E + E + + + Sbjct: 67 ESNIGELELEYQAKFPGDPLSVLREILIHVLESTV-TEERRRLLMEIIFHKCEFVGEMAV 125 Query: 118 VYRHRFSDLLDQYKK 132 V + + + L+ Y + Sbjct: 126 VQQAQRNLCLESYDR 140
>PF06580#Sensor histidine kinase Length = 349 Score = 38.3 bits (89), Expect = 4e-05 Identities = 21/118 (17%), Positives = 47/118 (39%), Gaps = 12/118 (10%) Query: 282 EAEQLEKLISELLELSRVKLSTNETKVHLGLAESLSQVLDDAEFEAEQQGKSIT--IDID 339 + + ++++ L EL R L + + LA+ L+ V + + Q + I+ Sbjct: 189 DPTKAREMLTSLSELMRYSLRYSNARQVS-LADELTVVDSYLQLASIQFEDRLQFENQIN 247 Query: 340 EEIELAHFPKSLSRAIENLLRNAIRYAASD------IQLQASATADQVKITIKDDGPG 391 I P L ++ L+ N I++ + I L+ + V + +++ G Sbjct: 248 PAIMDVQVPPML---VQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSL 302
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 96.4 bits (240), Expect = 2e-25 Identities = 44/163 (26%), Positives = 76/163 (46%), Gaps = 3/163 (1%) Query: 2 SRILLIDDDLGLSELLGQLLELEGFQLTLAYDGKQGLDLALSSDYDLILLDVMLPKLNGF 61 + IL+ DDD + +L Q L G+ + + + + D DL++ DV++P N F Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 EVLRALRQH-KQTPVLMLTARGDEIDRVVGLEIGADDYLPKPFNDRELIARIRAIIRRSN 120 ++L +++ PVL+++A+ + + E GA DYLPKPF+ ELI I + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 121 LTTQEIHAAPAQEFGDLRLDPSRQEAYCNEQLIILTGTEFTLL 163 ++ + + QE Y L L T+ TL+ Sbjct: 124 RRPSKLEDDSQDGMPLVGRSAAMQEIY--RVLARLMQTDLTLM 164
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 67.6 bits (165), Expect = 7e-16 Identities = 47/199 (23%), Positives = 70/199 (35%), Gaps = 22/199 (11%) Query: 2 MNKLSIVAISILSAFAATQVSAATDTTGFYVGGAL-------NRVTADAFDGSETGTGVG 54 M K +I AI++ A AT AA +Y G L + E G G Sbjct: 1 MKKTAI-AIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFINNNGPTHENQLGAG 59 Query: 55 VYGGYNFNEWFGLEANLFATGDL----GDKDVDISAGALSFTPKFTAQINDIFSAYAKVG 110 +GGY N + G E G + ++ A + T K I D Y ++G Sbjct: 60 AFGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPITDDLDIYTRLG 119 Query: 111 IASMAVNVDGYGYDEDF-TGFGWTYGVGVNAAVTEHLNIRVSYDVTT--GDLDADRSYLG 167 + Y ++ TG + GV A+T + R+ Y T GD Sbjct: 120 GMVWRADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDAHTI----- 174 Query: 168 LKDIDTDIKQFAVGVHYQF 186 D ++GV Y+F Sbjct: 175 --GTRPDNGMLSLGVSYRF 191
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 560 bits (1445), Expect = 0.0 Identities = 197/473 (41%), Positives = 294/473 (62%), Gaps = 11/473 (2%) Query: 7 VWILDDDSSIRWVLEKALQGAKLSTASFAAAESLWQALEISQPHVIVSDIRMPGTDGLSL 66 + + DDD++IR VL +AL A + A +LW+ + ++V+D+ MP + L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 67 LERLQVHYPHIPVIIMTAHSDLDSAVSAYQAGAFEYLPKPFDIDEAISLVERALTHATEQ 126 L R++ P +PV++M+A + +A+ A + GA++YLPKPFD+ E I ++ RAL + Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRR 125 Query: 127 SPAPAQEAQVKTPEIIGEAPAMQEVFRAIGRLSRSSISVLINGQSGTGKELVAGALHKHS 186 P+ ++ ++G + AMQE++R + RL ++ ++++I G+SGTGKELVA ALH + Sbjct: 126 -PSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYG 184 Query: 187 PRKDKPFIALNMAAIPKDLIESELFGHEKGAFTGAANVRQGRFEQANGGTLFLDEIGDMP 246 R++ PF+A+NMAAIP+DLIESELFGHEKGAFTGA GRFEQA GGTLFLDEIGDMP Sbjct: 185 KRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMP 244 Query: 247 LDVQTRLLRVLADGQFYRVGGHNAVQVDVRIIAATHQDLELLVQKGGFREDLFHRLNVIR 306 +D QTRLLRVL G++ VGG ++ DVRI+AAT++DL+ + +G FREDL++RLNV+ Sbjct: 245 MDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVP 304 Query: 307 VHLPPLSQRREDIPQLATHFLASAAKEIGVETKIMTKETAVKLSQLPWPGNVRQLENTCR 366 + LPPL R EDIP L HF+ A KE G++ K +E + PWPGNVR+LEN R Sbjct: 305 LRLPPLRDRAEDIPDLVRHFVQQAEKE-GLDVKRFDQEALELMKAHPWPGNVRELENLVR 363 Query: 367 WLTVMASGQEILPQDLPPELLKDPVSVTHTAKGSQDWQSALTEWIDQKLSE--------- 417 LT + I + + EL + ++ ++++ +++ + + Sbjct: 364 RLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDAL 423 Query: 418 GNSDLLTEVQPAFERILLETALRHTQGHKQEAAKRLGWGRNTLTRKLKELSMD 470 S L V E L+ AL T+G++ +AA LG RNTL +K++EL + Sbjct: 424 PPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>PF06580#Sensor histidine kinase Length = 349 Score = 38.7 bits (90), Expect = 3e-05 Identities = 36/188 (19%), Positives = 70/188 (37%), Gaps = 33/188 (17%) Query: 166 TLIIEQADRLRNLVDRL-------LGPQRPTQHSLHNIHQVVQKVYKLVEMALPANIQLK 218 LI+E + R ++ L L Q SL + VV +L + +Q + Sbjct: 184 ALILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFE 243 Query: 219 RDYDPSIPDIEMDPDQMQQAVLNILQNAVQALEHTGGEILLRTRTQHQVTIGSQRHKLVL 278 +P+I D+++ P +Q V N +++ + L GG+ILL+ + + Sbjct: 244 NQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQ-GGKILLKGTKDNGT----------V 292 Query: 279 TLSIIDNGPGIPPELMDTLFYPMVTGREQGSGLGLSIAHNIARLHSG---RIDCLSSAGH 335 TL + + G ++ +G GL ++ G +I G Sbjct: 293 TLEVENTGSLALKN------------TKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGK 340 Query: 336 TEFIISLP 343 ++ +P Sbjct: 341 VNAMVLIP 348
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 60.4 bits (146), Expect = 1e-13 Identities = 39/209 (18%), Positives = 64/209 (30%), Gaps = 13/209 (6%) Query: 1 MKIETQSTRQHILDIGYKLIVRKGFSSVGLSLLLQAAEVPKGSFYHYFKSKEQFGEALIT 60 K E Q TRQHILD+ +L ++G SS L + +AA V +G+ Y +FK K + Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 61 DYFEKYQLDLDALFNDSTLTGYQRLMQYWQQWLHVQADGCVDQKCLVVKLSAEVADLSEA 120 L + L + + + A Sbjct: 65 LSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMA 124 Query: 121 MRVALLKGSAG-IIDRLTTCVQVGINDSSIAEQ-DPQSTAEM-------LYHMWLGAS-- 169 + + DR+ ++ I + + A + L WL A Sbjct: 125 VVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQS 184 Query: 170 --LMNKLGHSPAALERALVTTKAILTPKT 196 L + A L + + P T Sbjct: 185 FDLKKEARDYVAILLEMYLLCPTLRNPAT 213
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 29.2 bits (65), Expect = 0.022 Identities = 21/96 (21%), Positives = 35/96 (36%), Gaps = 5/96 (5%) Query: 292 TVVVGAVIDPEMSDELRVTVVATGIGAEKRPDIQLVSKPAPRPEPVVVEPKVEAYVEEAV 351 T V + P + + VT+V E +Q +P PEP EP+ + Sbjct: 30 TSVHQVIELPAPAQPISVTMVTP-ADLEPPQAVQPPPEPVVEPEP---EPEPIPEPPKEA 85 Query: 352 HVNYAAPKGNVLPAAPQPAPQPAPSTKHELDYLDIP 387 V PK P P+P + K ++ ++ Sbjct: 86 PVVIEKPKPKPKP-KPKPVKKVQEQPKRDVKPVESR 120
>SECA#SecA protein signature. Length = 901 Score = 1316 bits (3407), Expect = 0.0 Identities = 651/907 (71%), Positives = 758/907 (83%), Gaps = 7/907 (0%) Query: 1 MFGKLLTKVFGSRNDRTLKGLQKIVISINALEADYEKLTDEALKAKTAEFRERLAAGASL 60 M KLLTKVFGSRNDRTL+ ++K+V INA+E + EKL+DE LK KTAEFR RL G L Sbjct: 1 MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVL 60 Query: 61 DSIMAEAFATVREASKRVFDMRHFDVQLLGGMVLDSNRIAEMRTGEGKTLTATLPAYLNA 120 ++++ EAFA VREASKRVF MRHFDVQLLGGMVL+ IAEMRTGEGKTLTATLPAYLNA Sbjct: 61 ENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNA 120 Query: 121 LTGKGVHVITVNDYLARRDAENNRPLFEFLGLTVGINVAGLGQHEKKAAYNADITYGTNN 180 LTGKGVHV+TVNDYLA+RDAENNRPLFEFLGLTVGIN+ G+ K+ AY ADITYGTNN Sbjct: 121 LTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNN 180 Query: 181 EFGFDYLRDNMAFSPQERVQRPLHYALIDEVDSILIDEARTPLIISGAAEDSSELYIKIN 240 E+GFDYLRDNMAFSP+ERVQR LHYAL+DEVDSILIDEARTPLIISG AEDSSE+Y ++N Sbjct: 181 EYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVN 240 Query: 241 TLIPNLIRQDKEDTEEYVGEGDYSIDEKAKQVHFTERGQEKVENLLIERGMLAEGDSLYS 300 +IP+LIRQ+KED+E + GEG +S+DEK++QV+ TERG +E LL++ G++ EG+SLYS Sbjct: 241 KIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYS 300 Query: 301 AANISLLHHVNAALRAHTLFERDVDYIVQDNEVIIVDEHTGRTMPGRRWSEGLHQAVEAK 360 ANI L+HHV AALRAH LF RDVDYIV+D EVIIVDEHTGRTM GRRWS+GLHQAVEAK Sbjct: 301 PANIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAK 360 Query: 361 EGVHIQNENQTLASITFQNYFRQYEKLAGMTGTADTEAFEFQHIYGLDTVVVPTNRPMVR 420 EGV IQNENQTLASITFQNYFR YEKLAGMTGTADTEAFEF IY LDTVVVPTNRPM+R Sbjct: 361 EGVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIR 420 Query: 421 KDMADLVYLTADEKYQAIIKDIKDCRERGQPVLVGTVSIEQSELLARLMVQEKIPHEVLN 480 KD+ DLVY+T EK QAII+DIK+ +GQPVLVGT+SIE+SEL++ + + I H VLN Sbjct: 421 KDLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLN 480 Query: 481 AKFHEREAEIVAQAGRTGSVTIATNMAGRGTDIVLGGNWNMEIDELDNPTAEQKAKIKAD 540 AKFH EA IVAQAG +VTIATNMAGRGTDIVLGG+W E+ L+NPTAEQ KIKAD Sbjct: 481 AKFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKAD 540 Query: 541 WQIRHDEVVAAGGLHILGTERHESRRIDNQLRGRAGRQGDAGSSRFYLSMEDSLMRIFAS 600 WQ+RHD V+ AGGLHI+GTERHESRRIDNQLRGR+GRQGDAGSSRFYLSMED+LMRIFAS Sbjct: 541 WQVRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFAS 600 Query: 601 DRVSGMMKKLGMEEGEAIEHPWVSRAIENAQRKVEARNFDIRKQLLEFDDVANDQRQVVY 660 DRVSGMM+KLGM+ GEAIEHPWV++AI NAQRKVE+RNFDIRKQLLE+DDVANDQR+ +Y Sbjct: 601 DRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIY 660 Query: 661 AQRNELMDAESIEDTIQNIQDDVIGAVIDQYIPPQSVEELWDIPGLEQRLHQEFMLKLPI 720 +QRNEL+D + +TI +I++DV A ID YIPPQS+EE+WDIPGL++RL +F L LPI Sbjct: 661 SQRNELLDVSDVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPI 720 Query: 721 QEWLDKEDDLHEESLRERIITAWGDAYKAKEEMVGAQVLRQFEKAVMLQTLDGLWKEHLA 780 EWLDKE +LHEE+LRERI+ + Y+ KEE+VGA+++R FEK VMLQTLD LWKEHLA Sbjct: 721 AEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLA 780 Query: 781 AMDHLRQGIHLRGYAQKNPKQEYKRESFELFQQLLNTLKHDVISVLSKVQVQAQSDVEEM 840 AMD+LRQGIHLRGYAQK+PKQEYKRESF +F +L +LK++VIS LSKVQV+ +VEE+ Sbjct: 781 AMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEEL 840 Query: 841 EARRREEDAKIQRDYQHAAAESLVGGGDEHEAVTAQAPMIRDGEKVGRNDPCPCGSGRKY 900 E +RR E A + D+ A A KVGRNDPCPCGSG+KY Sbjct: 841 EQQRRMEAE-------RLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKY 893 Query: 901 KQCHGKL 907 KQCHG+L Sbjct: 894 KQCHGRL 900
>PF02370#M protein repeat Length = 168 Score = 30.8 bits (69), Expect = 0.009 Identities = 22/83 (26%), Positives = 33/83 (39%), Gaps = 9/83 (10%) Query: 380 SLVLAIRYN--DERKAKLRIQQEALKQAQKIRSAREE-----ALKAEAESNEKLEQMVQE 432 + L YN E +KL+ Q E + S RE AL E + K E Q+ Sbjct: 12 NGKLITEYNKLVEENSKLQKQLE--EYLDSSDSKRENDPQYRALMGENQDLRKREGQYQD 69 Query: 433 RTLELEITLRELHEVNQKLTEQS 455 + ELE +E E ++ + Sbjct: 70 KIEELEKERKEKQERPERREKFE 92 Score = 30.8 bits (69), Expect = 0.010 Identities = 13/69 (18%), Positives = 32/69 (46%) Query: 389 DERKAKLRIQQEALKQAQKIRSAREEALKAEAESNEKLEQMVQERTLELEITLRELHEVN 448 D RK + + Q + + ++ + +E + E + ++ QE+ + + ++L Sbjct: 59 DLRKREGQYQDKIEELEKERKEKQERPERREKFERQHQDKHYQEQQKKHQQEQQQLEAEK 118 Query: 449 QKLTEQSTI 457 QKL ++ I Sbjct: 119 QKLAKEKQI 127
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 50.6 bits (121), Expect = 4e-09 Identities = 44/256 (17%), Positives = 89/256 (34%), Gaps = 43/256 (16%) Query: 36 WYLLLLLVIAPVAIVGWILLRP-HLFVLASGIVTT--EPLEVRAPSTGDVSTIRVKPGDT 92 ++++ LVIA +L + A+G +T E++ V I VK G++ Sbjct: 62 YFIMGFLVIA----FILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGES 117 Query: 93 LNVGTPILSISDPQLNAQITELERQLAQL------------NIEDLSLNSVILKQLQTRI 140 + G +L ++ A + + L Q +IE L + L Sbjct: 118 VRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQ 177 Query: 141 DVANEGVTRQDILLKS-YENFQR-------KGVVPTSDMATVLQAHTASKMALEQAKVDL 192 +V+ E V R L+K + +Q ++ TVL + K L Sbjct: 178 NVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRL 237 Query: 193 ----------------MQAKQKQLVELSAGVVTQSRRSIELQLARLKAQQSQLQIKALTA 236 + ++ + VE + + +++ L A++ + L Sbjct: 238 DDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFK 297 Query: 237 TRVVDILVQSGEHIVE 252 ++D L Q+ ++I Sbjct: 298 NEILDKLRQTTDNIGL 313 Score = 34.0 bits (78), Expect = 7e-04 Identities = 34/208 (16%), Positives = 70/208 (33%), Gaps = 37/208 (17%) Query: 107 LNAQITELERQLAQLNIEDLSLNSVILKQLQTRIDVANEGVTRQDILLKSYENFQRKGVV 166 + Q + + Q Q + + L L N + L + + K + Sbjct: 191 IKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKS-RLDDFSSLLHKQAI 249 Query: 167 PTSDMATVLQAHTASKMALEQAKVDLMQAKQK-QLVELSAGVVTQSRRS----------- 214 + + + L K L Q + + + +VTQ ++ Sbjct: 250 AKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTD 309 Query: 215 ----IELQLARLKAQQSQLQIKALTATRVVDI-------LVQSGEHIV----EDRPLALL 259 + L+LA+ + +Q I+A + +V + +V + E ++ ED L Sbjct: 310 NIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTL--- 366 Query: 260 AGRDNPVVLAFLEPKYLNYTTIGQQATI 287 V A ++ K + + +GQ A I Sbjct: 367 ------EVTALVQNKDIGFINVGQNAII 388
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 71.0 bits (174), Expect = 4e-16 Identities = 44/182 (24%), Positives = 70/182 (38%), Gaps = 24/182 (13%) Query: 3 KIMVTGATGLLGRAVVKQLELTGHEVV-----------------ATGFSRASERVHKLDL 45 K +VTGA G +G V K+L GH+VV ++ + HK+DL Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 46 TAPLAVEAFIAREQPQVIVHCAAERRPDVSEQNPQAALALNLTASQALAMAAKANN-AWL 104 + A + + S +NP A NLT + + N L Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 105 IYISTDYVFDGTQ--PKYAEDAATHPVNFYGESKLKGEEIVLNTSDDFAV----LRLPIL 158 +Y S+ V+ + P +D+ HPV+ Y +K E + S + + LR + Sbjct: 122 LYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFFTV 181 Query: 159 YG 160 YG Sbjct: 182 YG 183
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 92.2 bits (229), Expect = 3e-24 Identities = 26/129 (20%), Positives = 64/129 (49%) Query: 3 RLLIVEDDLSLASILGRRLTRHGFECRLTHDASDALLVAREFRPSHILLDMKLAEANGLG 62 +L+ +DD ++ ++L + L+R G++ R+T +A+ ++ D+ + + N Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 63 LIVPLRNLLPKVTMVLLTGYASIATAVEAIRLGADNYLAKPVDTQTLLAALEMEGHSHTL 122 L+ ++ P + +++++ + TA++A GA +YL KP D L+ + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 123 QEDEVDDSP 131 + +++D Sbjct: 125 RPSKLEDDS 133 Score = 47.1 bits (112), Expect = 1e-08 Identities = 13/39 (33%), Positives = 22/39 (56%) Query: 135 KRLEWEHIQQVLNANQGNVSATARQLGMHRRTLQRKLLK 173 +E+ I L A +GN A LG++R TL++K+ + Sbjct: 434 AEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRE 472
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 1e-04 Identities = 7/21 (33%), Positives = 13/21 (61%) Query: 1 MSATARQLGMHRRTLQRKLLK 21 A LG++R TL++K+ + Sbjct: 452 QIKAADLLGLNRNTLRKKIRE 472
>THERMOLYSIN#Thermolysin metalloprotease (M4) family signature. Length = 544 Score = 361 bits (927), Expect = e-118 Identities = 133/490 (27%), Positives = 191/490 (38%), Gaps = 51/490 (10%) Query: 44 SQFNL--DAGSQLKVEKKLDLGQGKQKQRLQQYFHDVPVYGFSVATSQSSMGFYSDMSGR 101 + F L A +L + G R +Q G + + S +SG Sbjct: 64 NTFQLGGQARERLSLIGNKLDELGHTVMRFEQAIAASLCMGAVLVAHVNDGELSS-LSGT 122 Query: 102 VLKNIEKSADFVKPTLTANKALDIAIRGKSEK-AVAGLKAENKQAKLWLYLDDAAKTRLV 160 ++ N++K + ++ +A IA + +++ AE + + D RL Sbjct: 123 LIPNLDKRTLKTEAAISIQQAEMIAKQDVADRVTKERPAAEEGKPTRLVIYPDEETPRLA 182 Query: 161 YVTSFVVYGDEPSRPFTMIDAHSGEVLKRWEGINHA-ASGTGPGGNIKTGQYEYGTDFSY 219 Y + P MIDA G+VL +W ++ A G P T G Sbjct: 183 YEVNVRFLTPVPGNWIYMIDAADGKVLNKWNQMDEAKPGGAQPVAGTSTVGVGRG----- 237 Query: 220 LDVEVSGDT---CTMNSPNVKTVNLNGATSGATAFSYTCPRNTV-----------KEING 265 V GD T S L T G+ F+Y TV + Sbjct: 238 ----VLGDQKYINTTYSSYYGYYYLQDNTRGSGIFTYDGRNRTVLPGSLWADGDNQFFAS 293 Query: 266 AYSPLNDAHYFGNVIYNMYSEWYN---TAPLTFQLTMRVHYSSNYENAFWDGSAMTFGDG 322 + DAHY+ V+Y+ Y + + VHY Y NAFW+GS M +GDG Sbjct: 294 YDAAAVDAHYYAGVVYDYYKNVHGRLSYDGSNAAIRSTVHYGRGYNNAFWNGSQMVYGDG 353 Query: 323 -ATTFYPLV-SLDVSAHEVSHGFTEQNSGLIYDAQSGGMNEAFSDMAGEAAEFYMHGTND 380 TF P +DV HE++H T+ +GL+Y +SG +NEA SD+ G EFY + D Sbjct: 354 DGQTFLPFSGGIDVVGHELTHAVTDYTAGLVYQNESGAINEAMSDIFGTLVEFYANRNPD 413 Query: 381 WLVGADIFK---GNGALRYMADPTLDGISIGHIDDYYDGID---VHHSSGVFNKAFYTLA 434 W +G DI+ ALR M+DP G + Y D VH +SG+ NKA Y L+ Sbjct: 414 WEIGEDIYTPGVAGDALRSMSDPAKYGDPDHYSKRYTGTQDNGGVHTNSGIINKAAYLLS 473 Query: 435 N--------LPGWDTRTAFQTFVVANQLYWTADSLFWQGACGVKSAATDLG----LSADD 482 + G + F A Y T S F Q AA DL + Sbjct: 474 QGGVHYGVSVTGIGRDKMGKIFYRALVYYLTPTSNFSQLRAACVQAAADLYGSTSQEVNS 533 Query: 483 VVTAFAAVGI 492 V AF AVG+ Sbjct: 534 VKQAFNAVGV 543
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 59.3 bits (143), Expect = 1e-12 Identities = 46/241 (19%), Positives = 87/241 (36%), Gaps = 47/241 (19%) Query: 3 VLIVGGSGGIGQAMVKQVQEAYPEATVHATYRHHLPQDRQNNIQWHA----------LDV 52 I G + GIG+A V H + P+ + + DV Sbjct: 11 AFITGAAQGIGEA----VARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADV 66 Query: 53 TNEAEIKQLSEQLTE----LDWLINCVGILHTQDKGPEKSLQSLDLAFFQHNLTLNTLPS 108 + A I +++ ++ +D L+N G+L G + SL ++ ++N+ Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRP---GL---IHSLSDEEWEATFSVNSTGV 120 Query: 109 VMLAKHFCHALKQSDSARFAVISAKVGSITDNRLGGWYSYRASKAALNMFLKTLSIEWQR 168 ++ + S + + + + +Y +SKAA MF K L +E Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMA---AYASSKAAAVMFTKCLGLELAE 177 Query: 169 NMKHCVVLSLHPGTTDTPLSQP------------------FQQSVPKGKLFTPEYVANCL 210 C ++S PG+T+T + F+ +P KL P +A+ + Sbjct: 178 YNIRCNIVS--PGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAV 235 Query: 211 L 211 L Sbjct: 236 L 236
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.6 bits (69), Expect = 0.013 Identities = 11/36 (30%), Positives = 18/36 (50%), Gaps = 3/36 (8%) Query: 49 TPKNILMIGPTGVGKTEIAR---RLAKLANAPFIKV 81 T +++ G +G GK +AR K N PF+ + Sbjct: 159 TDLTLMITGESGTGKELVARALHDYGKRRNGPFVAI 194
>PF06580#Sensor histidine kinase Length = 349 Score = 28.7 bits (64), Expect = 0.015 Identities = 11/53 (20%), Positives = 20/53 (37%), Gaps = 2/53 (3%) Query: 25 LGAYAAGFLVLFAALGGYSYWQVSELQQAQQLAAQQ--KLQFDTQKQALEAQI 75 L +V F Y W + + ++ + + + Q AL+AQI Sbjct: 118 LSIIFNVVVVTFMWSLLYFGWHFFKNYKQAEIDQWKMASMAQEAQLMALKAQI 170
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 179 bits (455), Expect = 5e-51 Identities = 72/293 (24%), Positives = 129/293 (44%), Gaps = 26/293 (8%) Query: 257 PQAGLVTIRAFPSELRQVRTFLNSAESHLQRQVILEAKIIEVTLSDGYQQGIQWENVLGH 316 Q + + A P + + + + + QV++EA I EV +DG GIQW N Sbjct: 316 GQTNALIVTAAPDVMNDLERVIAQLDIR-RPQVLVEAIIAEVQDADGLNLGIQWANKNAG 374 Query: 317 VGN-------TNVNFGTSKGPGLSDKITSAIGGVTS------LSIKGSDFTTMINLLDTQ 363 + + + ++S++ S ++ ++ L + Sbjct: 375 MTQFTNSGLPISTAIAGANQYNKDGTVSSSLASALSSFNGIAAGFYQGNWAMLLTALSSS 434 Query: 364 GDVDVLSSPRVTASNNQKAVIKVGTDEYFVTDVSSTTVAGATPVTTPQVELTPFFSGIAL 423 D+L++P + +N +A VG + +T S T +G T + + GI L Sbjct: 435 TKNDILATPSIVTLDNMEATFNVGQEVPVLT--GSQTTSGDNIFNTVERKTV----GIKL 488 Query: 424 DVTPQIDSDGNVLLHVHPSVIDVKEQTKDIKVSDASLELPLAQSEIRESDTVIRAASGDV 483 V PQI+ +VLL + V V + S S +L + R + + SG+ Sbjct: 489 KVKPQINEGDSVLLEIEQEVSSVADAA-----SSTSSDLGATFN-TRTVNNAVLVGSGET 542 Query: 484 VIIGGLMKSENTEVVSQVPLLGDIPFLGELFKNRSKQKKKTELIILLKPTVVG 536 V++GGL+ ++ +VPLLGDIP +G LF++ SK+ K L++ ++PTV+ Sbjct: 543 VVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRNLMLFIRPTVIR 595
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 40.8 bits (95), Expect = 1e-05 Identities = 33/164 (20%), Positives = 63/164 (38%), Gaps = 23/164 (14%) Query: 63 AEPAEATASSQAQEQNTLTAQ----TESVRIDSVASEEASPNVDAAAKPLKLATTQKIAA 118 +E E A + QE T+ TE+ + ++EA NV A + ++A + Sbjct: 1034 SETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSG---- 1089 Query: 119 AMTANSEEFEPSATEVASSQAPELGTAKEAEHEQQAQSQSQPQQKPQAD------VSLEL 172 + ++E + + T+ ++ E AK + Q + Q P+ + E Sbjct: 1090 ---SETKETQTTETKETATVEKE-EKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEP 1145 Query: 173 ANDQVDTVS-----EPSHSQPSHSQPSSATSSVRSAEVTVAAPS 211 A + TV+ +++ QP+ TSS VT + Sbjct: 1146 ARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTV 1189
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 302 bits (776), Expect = e-102 Identities = 116/407 (28%), Positives = 207/407 (50%), Gaps = 6/407 (1%) Query: 1 MPIYQYRGRSGQGQSVTGQLDAASESAAADMLLARGIIPLEVKVAKVVK----SFSLAQL 56 M Y Y+ QG+ G +A S A +L RG++PL V + + S L+ Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 57 FGGKVALEELQIFTRQMYSLTRSGIPILRAIAGLSETAHSQRMKDALNDISEQLTAGRPL 116 +++ +L + TRQ+ +L + +P+ A+ +++ + + + + ++ G L Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 117 SSSMNQHPDVFDSLFVSMVHVGENTGKLEDAFIQLSGYIEREQETRRRIKSAMRYPMFVL 176 + +M P F+ L+ +MV GE +G L+ +L+ Y E+ Q+ R RI+ AM YP VL Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPC-VL 179 Query: 177 ISIALAMV-ILNIMVIPKFAEMFSRFGADLPWATKVLIGTSNLFVNYWALMLVALIGTII 235 +A+A+V IL +V+PK E F LP +T+VL+G S+ + ML+AL+ + Sbjct: 180 TVVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFM 239 Query: 236 GIRYWHHTEKGEKQWDKWKLHIPAVGSIIERSTLARYCRSFSMMLSAGVPMTQALSLVAD 295 R EK + + LH+P +G I ARY R+ S++ ++ VP+ QA+ + D Sbjct: 240 AFRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGD 299 Query: 296 AVDNAYMHDKIVGMRRGIESGDSMLRVSNQSKLFTPLVLQMVAVGEETGQIDQLLNDAAD 355 + N Y ++ + G S+ + Q+ LF P++ M+A GE +G++D +L AAD Sbjct: 300 VMSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAAD 359 Query: 356 FYEGEVDYDLKNLTAKLEPILIGFVAVIVLVLALGIYLPMWDMLNVV 402 + E + EP+L+ +A +VL + L I P+ + ++ Sbjct: 360 NQDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 29.2 bits (65), Expect = 0.033 Identities = 11/41 (26%), Positives = 21/41 (51%), Gaps = 4/41 (9%) Query: 124 LAAGLSSSGALVVAFGTAISDTSQLHLSPMAVAQLAQRGEH 164 A GLS+S A +A++ L +SP++ +A + + Sbjct: 296 AAQGLSTSAAAAGLIASAVT----LAISPLSFLSIADKFKR 332
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 29.7 bits (67), Expect = 0.033 Identities = 27/159 (16%), Positives = 56/159 (35%), Gaps = 13/159 (8%) Query: 146 VAIGILIMQDIFAVLFLTISKGDVPSVWAFALLLLPLAKPLIYKAFDRVGHGELLVLFGL 205 + + + ++ + + +P A + ++ + Y F + + L + Sbjct: 43 MGLSDYYFEHFSKLMLIPAEQSYLPFSQALSYVVDNVLLEFFYLCFPLLT---VAALMAI 99 Query: 206 VMALVVGAWLFESVGLKPDLGAL--IIGI-LLAGHKKSSELAKSLFYFKELFLVAFFLTI 262 +V +L +KPD+ + I G + K E KS+ L ++ + + Sbjct: 100 ASHVVQYGFLISGEAIKPDIKKINPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIK 159 Query: 263 G----LNGLPTVSDIVLAALLVLLVPLKILLFVYILTRF 297 G L LPT + + LL + L V F Sbjct: 160 GNLVTLLQLPTCG---IECITPLLGQILRQLMVICTVGF 195
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 492 bits (1269), Expect = e-159 Identities = 212/1049 (20%), Positives = 443/1049 (42%), Gaps = 58/1049 (5%) Query: 3 IAEYSIRHKVISWMFVLLLLVGGGVSFTGLGQLEFPEFTIKEALVITAYPGASPEQVEEE 62 +A + IR + +W+ ++L++ G ++ L ++P V YPGA + V++ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 63 VTLPLEDALQQLDAIKHVTSI-NSAGLSQIQIEIKESYDKTSLPQVWDEVRRKVNDTAGS 121 VT +E + +D + +++S +SAG I + + T +V+ K+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQ---SGTDPDIAQVQVQNKLQLATPL 117 Query: 122 LPPGTTAPQVMDDFGD---VYGILFNLSGPDYSNRELSNYAD-YLRRELVLVPGVKKVSV 177 LP + + + F P + ++S+Y ++ L + GV V + Sbjct: 118 LPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQL 177 Query: 178 AGSVTEQVVIEISQQKLSALGLDQSYIYGLVNNQNVVSNAGSLVIGDN------RIRIHP 231 G+ + I + L+ L + + QN AG L I Sbjct: 178 FGA-QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIA 236 Query: 232 TGEFSNVQDLARLIVSPPGSTELIYLGDIANIEKDYDETPNVLYHNKGEAALSLGISFSS 291 F N ++ ++ + ++ L D+A +E + + N G+ A LGI ++ Sbjct: 237 QTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARIN-GKPAAGLGIKLAT 295 Query: 292 GVNVVEVGQKVSNRLAELESQRPIGMNLATVYNQSQAVDETVNGFLINLLESIAIVIAVL 351 G N ++ + + +LAEL+ P GM + Y+ + V +++ + L E+I +V V+ Sbjct: 296 GANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVM 355 Query: 352 LLFMG-LRSGLLMGLILLLTILGTFIVMKVLGIELQLISLGALIIALGMLVDNAIVVTEG 410 LF+ +R+ L+ + + + +LGTF ++ G + +++ +++A+G+LVD+AIVV E Sbjct: 356 YLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVEN 415 Query: 411 ILIGLRRGKTR-LEAAKQIVAQTQWPLLGATVIAIIAFAPIGLSQNAAGEFCRSLFQVLM 469 + + K EA ++ ++Q Q L+G ++ F P+ + G R ++ Sbjct: 416 VERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIV 475 Query: 470 ISLFISWITAITLTPFFCHLLFKDAPSDE-EAQDPYKGWF-------FSLYRASLTLALR 521 ++ +S + A+ LTP C L K ++ E + + GWF + Y S+ L Sbjct: 476 SAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILG 535 Query: 522 FRLVSILLVVAMLFSAVVGFGHIKNVFFPASNTPIFFVDIWMPEGTDIKATERFTADIER 581 +L+ ++ VV F + + F P + +F I +P G + T++ + Sbjct: 536 STGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTD 595 Query: 582 LMLSLNEQKDVGLKHLTTVIG-------QGSQRFVLPYQPEKGYPAFAQLIVEMQDLAAV 634 L NE+ +V + + TV G Q + + +P + + A Sbjct: 596 YYLK-NEKANV--ESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIH-RAK 651 Query: 635 KAYMPELETLLNQRFPQAQYRLKNMENGPSPAAKIEARFYGDNPEVLRALGDQAEAIFHA 694 + + P + + ++ + + + +A Sbjct: 652 MELGKIRDGFV---IPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQH 708 Query: 695 EPSMDGIRHNWRNQVPLIRPQLENAQARETGISKQDLDNALLVNFSGKQIGLYRETSHLL 754 S+ +R N + +++ +A+ G+S D++ + G + + + + Sbjct: 709 PASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVK 768 Query: 755 PIVARAPAEERLQADSLWKLQIWSSEHNTFVPATQVVSNFNTEWEN--PLVMRRDRMRML 812 + +A A+ R+ + + KL + S + VP + + + W P + R + + + Sbjct: 769 KLYVQADAKFRMLPEDVDKLYV-RSANGEMVPFSAFTT---SHWVYGSPRLERYNGLPSM 824 Query: 813 AVMADPKLGSD-ETADSVLRKVKDKVEAISLPAGYHLEWGGEFETAGEAQTAVFSSIPMG 871 + + G+ A +++ + K LPAG +W G + + + + Sbjct: 825 EIQGEAAPGTSSGDAMALMENLASK-----LPAGIGYDWTGMSYQERLSGNQAPALVAIS 879 Query: 872 YLAMFLITVFLFNSVRQPLVIWFTVPLALIGVSAGLLLFDAPFSFMALLGLLSLSGMVIK 931 ++ +FL L+ S P+ + VPL ++GV LF+ ++GLL+ G+ K Sbjct: 880 FVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAK 939 Query: 932 NGIVLVDQIN-LELSEGKPAYFALVDSCVSRVRPVMMAAITTMLGMIPLISDAFFGS--- 987 N I++V+ L EGK A + + R+RP++M ++ +LG++PL GS Sbjct: 940 NAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQ 999 Query: 988 --MAITIIFGLGFASLLTLIVLPVMYSLV 1014 + I ++ G+ A+LL + +PV + ++ Sbjct: 1000 NAVGIGVMGGMVSATLLAIFFVPVFFVVI 1028 Score = 74.5 bits (183), Expect = 1e-15 Identities = 39/209 (18%), Positives = 95/209 (45%), Gaps = 13/209 (6%) Query: 822 SDETADSVLRKVKDKVEAI--SLPAGYHLEWGGEFETAGEAQTAVFSSIPMGYLAMFL-- 877 + A + +K K+ + P G ++ ++T Q ++ + + A+ L Sbjct: 295 TGANALDTAKAIKAKLAELQPFFPQG--MKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVF 352 Query: 878 ITVFLF-NSVRQPLVIWFTVPLALIGVSAGLLLFDAPFSFMALLGLLSLSGMVIKNGIVL 936 + ++LF ++R L+ VP+ L+G A L F + + + G++ G+++ + IV+ Sbjct: 353 LVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVV 412 Query: 937 VDQINLELSEGKPAYFALVDSCVSRVR-PVMMAAITTMLGMIPL-----ISDAFFGSMAI 990 V+ + + E K + +S+++ ++ A+ IP+ + A + +I Sbjct: 413 VENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSI 472 Query: 991 TIIFGLGFASLLTLIVLPVMYSLVFNIKA 1019 TI+ + + L+ LI+ P + + + + Sbjct: 473 TIVSAMALSVLVALILTPALCATLLKPVS 501
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 45.2 bits (107), Expect = 2e-07 Identities = 29/178 (16%), Positives = 62/178 (34%), Gaps = 28/178 (15%) Query: 104 EAEHELLAADFKRKIELLNRKLISQSEFDSTQAQLKSAKAALAAARDQLSYTRLTAPFSG 163 + E++L+ FK +I + T + LA ++ + + AP S Sbjct: 286 KEEYQLVTQLFKNEI---------LDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSV 336 Query: 164 TIAKRLVDNH-QIVQANQGVLTL-QNNNLLDVSIQVPEAMAAGLKQYTDQAHFTAKVRFS 221 + + V +V + ++ + ++ L+V+ V Q A ++ Sbjct: 337 KVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIG--FINVGQN---AIIKVE 391 Query: 222 AFPEQSF---DAKFKEYSTQVTPGTQ---AYEVVFSLPQPL------DIQLLPGMSAE 267 AFP + K K + + + V+ S+ + +I L GM+ Sbjct: 392 AFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVT 449 Score = 31.3 bits (71), Expect = 0.005 Identities = 15/104 (14%), Positives = 37/104 (35%), Gaps = 2/104 (1%) Query: 68 SGQLTELTLVEGQRVAQGSLLAQLDDRDAKNNLMTREAEHELLAADFKRK-IELLNRKLI 126 + + E+ + EG+ V +G +L +L A+ + + ++ + R I + +L Sbjct: 104 NSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELN 163 Query: 127 SQSEFD-STQAQLKSAKAALAAARDQLSYTRLTAPFSGTIAKRL 169 E + ++ L + + + K L Sbjct: 164 KLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKEL 207
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 167 bits (424), Expect = 6e-51 Identities = 85/328 (25%), Positives = 143/328 (43%), Gaps = 33/328 (10%) Query: 60 YMGSEIGINHYQHGC-ESWSIDCDKNSTMASFFAGYQFNHHLAFEVAYIDLGKAEATYLE 118 Y G+++G + Y + + +N A F GYQ N ++ FE+ Y LG+ Y Sbjct: 29 YTGAKLGWSQYHDTGFINNNGPTHENQLGAGAFGGYQVNPYVGFEMGYDWLGRM--PYKG 86 Query: 119 ASKQNIYQGSMRGLNLSSVASIDFGADLALFAKAGVFNWHGENKGPFSTIKADD-WSPSF 177 + + Y +G+ L++ DL ++ + G W + K D SP F Sbjct: 87 SVENGAY--KAQGVQLTAKLGYPITDDLDIYTRLGGMVWRADTKSNVYGKNHDTGVSPVF 144 Query: 178 GVGMTYQLSDSWQARLQYEYFHHLGNDDIGGTNA--HATSLGISYQFGRSRPEVITSTVI 235 G+ Y ++ RL+Y++ +++G+ GT SLG+SY+FG+ + Sbjct: 145 AGGVEYAITPEIATRLEYQWTNNIGDAHTIGTRPDNGMLSLGVSYRFGQGEAAPV----- 199 Query: 236 NSVTNTVIKATPIELEEVTFP--VLFNFDSSELF--FVDSLQIIINRLIQF--PQATVIL 289 V A ++ + T VLFNF+ + L +L + ++L +V++ Sbjct: 200 --VAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVV 257 Query: 290 RGYSDSQGSSEYNLALSKRRTDSITQYLTEHGVKPQQIIAEHYGEQYPVTDKISEQHKHL 349 GY+D GS YN LS+RR S+ YL G+ +I A GE PVT + K Sbjct: 258 LGYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQR 317 Query: 350 ---------NRRVQVLL---PQTIIQPQ 365 +RRV++ + + QPQ Sbjct: 318 AALIDCLAPDRRVEIEVKGIKDVVTQPQ 345
>FLAGELLIN#Flagellin signature. Length = 507 Score = 30.8 bits (69), Expect = 0.045 Identities = 35/307 (11%), Positives = 76/307 (24%), Gaps = 9/307 (2%) Query: 425 DGSKKDITQLAAWSSSEPSVAAIQFSGALSGVANTLAIGNTDITVSFEGMSKTTTLTVNQ 484 + Q+ A ++ + G+ G + TV S + Sbjct: 138 SQDNQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKEATVGDLKSSFKNVTGYDT 197 Query: 485 AVVESVQITPQNPSVPVGVEGQFTAIAFYSDKTTVDVTHSANWQVDDYSIAAVIPNGDSA 544 V + + V G T DK V+ + D + AV + Sbjct: 198 YAVGANKYRV---DVNSGAVVTDTTAPTVPDKVYVNAANGQLTTDDAENNTAVDLFKTTK 254 Query: 545 GYAKALGEGTNQLSVK------FSGQTASTSISVSAAKLDSISLTPSIAEAPAGTTLQYQ 598 A ++K T + D + T Sbjct: 255 STAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGNGKVSTTINGEKVTLTVAD 314 Query: 599 VFGLFSDGTNHDLTTFAHYQTSDNALASIDSHGLATAHQYNAKPVTVTASYDGLQSTATL 658 + ++ L + + TS + A + T Sbjct: 315 ITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSDLEANNAVKGESKITVNG 374 Query: 659 KVTAGLLDHIEVTPAAQSIAVGHKGLLQARAFYSDKTSSDITSLATWSVNDGDIASVDNT 718 +VT A +++ + + D ++ ++ + D ++ VD Sbjct: 375 AEYTANAAGDKVTLAGKTMFIDKTASGVSTLINEDAAAAKKSTANPLASIDSALSKVDAV 434 Query: 719 EAESGSV 725 + G++ Sbjct: 435 RSSLGAI 441
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 28.4 bits (63), Expect = 0.017 Identities = 16/60 (26%), Positives = 34/60 (56%), Gaps = 1/60 (1%) Query: 112 QQYLTNKRLSEIADRLNAIDREISSLDGKINNLTDKADLLKQKNSLLNEKNQLLDERSRL 171 Q N + D++N ++I+SL+ +I+ LT N+LL++++QL+ E +++ Sbjct: 153 QDKQVNIAIGASVDQINNYAKQIASLNDQISRLTGVGA-GASPNNLLDQRDQLVSELNQI 211
>PF04183#IucA / IucC family Length = 580 Score = 24.5 bits (53), Expect = 0.049 Identities = 6/44 (13%), Positives = 15/44 (34%) Query: 20 GRLLSDVARQYGLSAKAVYQWVRESDLQPQQRECALMSEIAQLQ 63 R +S + + G+ + YQ + ++ + A Sbjct: 489 LRFISPLMVRLGVPERRFYQLLAAVLSDYMKKHPQMSERFALFS 532
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 97.3 bits (242), Expect = 4e-26 Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 11/123 (8%) Query: 117 LNMPNEVTFGVDQTELSDGAKRVLNSVAVVAKEYSKT--QLNVLGYTDSSGSDSYNLRLS 174 + ++V F ++ L + L+ + + VLGYTD GSD+YN LS Sbjct: 215 FTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLS 274 Query: 175 QVRAGEVGNYLMSKGVASARVKSKGMGEASPIASNANANGR---------AQNRRVEIVL 225 + RA V +YL+SKG+ + ++ ++GMGE++P+ N N + A +RRVEI + Sbjct: 275 ERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEV 334 Query: 226 TPT 228 Sbjct: 335 KGI 337
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 30.5 bits (69), Expect = 0.014 Identities = 19/124 (15%), Positives = 43/124 (34%), Gaps = 13/124 (10%) Query: 2 PVDNSENDHT---GHSLDQLNQALSSGMFVHVRNMLQK-MAASDIALILESSPPSARQVL 57 + + D+ L + + G + R +L+K + I+ + + Sbjct: 57 TITSELKDNVLLEFKELMMAQEFIQKGGIDYARELLEKSLGTQKAVDIINNLGSA----- 111 Query: 58 WQLIDQEQIGDILDELSEELKDPLIRSMSPERVAKATASMDTDDLAYILRSLPDAVYKQV 117 Q + + + I+ P+ +A + +D ++IL SLP V V Sbjct: 112 ----LQSRPFEFVRRADPANILNFIQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNV 167 Query: 118 LQSM 121 + + Sbjct: 168 ARRI 171
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 541 bits (1395), Expect = 0.0 Identities = 170/668 (25%), Positives = 292/668 (43%), Gaps = 60/668 (8%) Query: 6 KYRNIGIFAHVDAGKTTTTERILKLTGKIHKIGEVHDGESTTDFMVQEAERGITIQSAAV 65 K NIG+ AHVDAGKTT TE +L +G I ++G V G + TD + E +RGITIQ+ Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 66 SCFWKDHRFNVIDTPGHVDFTVEVYRSLKVLDGGIGVFCGSGGVEPQSETNWRYANESEV 125 S W++ + N+IDTPGH+DF EVYRSL VLDG I + GV+ Q+ + + + Sbjct: 62 SFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGI 121 Query: 126 ARIIFVNKLDRMGADFLRVVKQTKDVLAATPLVMVLPIGVEDEFTGVVDLLTRKAYVWDD 185 I F+NK+D+ G D V + K+ L+A ++ +K ++ + Sbjct: 122 PTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIK------------------QKVELYPN 163 Query: 186 SGLPENFEVLDVPADMVDMVEEYREMLIETAVEQDDAVMEAYMEGEEPSMEDIKRCIRTG 245 + + + +T +E +D ++E YM G+ ++++ Sbjct: 164 ----------MCVTNFTESEQ------WDTVIEGNDDLLEKYMSGKSLEALELEQEESIR 207 Query: 246 TRKLAFFPTYCGSAFKNKGMQLVLDAVVDYLPAPDEVDPQPLTDEEGNETGEFAIVSADE 305 + FP Y GSA N G+ +++ + + + Sbjct: 208 FHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSSTH--------------------RGQS 247 Query: 306 PLKALAFKI-MDDRFGALTFVRIYSGRLKKGDTILNSATGKTERIGRMCEMYADDRIEIE 364 L FKI ++ L ++R+YSG L D++ S K +I M + +I+ Sbjct: 248 ELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEK-IKITEMYTSINGELCKID 306 Query: 365 SAQAGDIIAIVGMKNVQTGHTLCDVKHPVTLEAMVFPEPVISIAVAPKDKGGSEKMGIAI 424 A +G+I+ + + ++ L D K E + P P++ V P E + A+ Sbjct: 307 KAYSGEIVILQN-EFLKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQREMLLDAL 365 Query: 425 GKMIAEDPSFRVETDEDSGETILKGMGELHLDIKVDILKRTYGVELIVGEPQVAYRETIT 484 ++ DP R D + E IL +G++ +++ +L+ Y VE+ + EP V Y E Sbjct: 366 LEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIKEPTVIYMERPL 425 Query: 485 QMVEDQYTHKKQSGGSGQFGKIEYIIRPGEPNTGFVFKSSVVGGSVPKEFWPAVEKGFAS 544 + E YT + + + I + P +G ++SSV G + + F AV +G Sbjct: 426 KKAE--YTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRY 483 Query: 545 MMNTGTIAGFPVLDVEFELTDGAFHAVDSSAIAFEIAAKGAFRQSIAKAKPQLLEPIMKV 604 G + G+ V D + G +++ S+ F + A Q + KA +LLEP + Sbjct: 484 GCEQG-LYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSF 542 Query: 605 DVFSPDDNVGDVIGDLNRRRGMIKDQVAGVTGVRVKADVPLSEMFGYIGTLRTMTSGRGQ 664 +++P + + D + I D V + ++P + Y L T+GR Sbjct: 543 KIYAPQEYLSRAYTDAPKYCANIVDTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSV 602 Query: 665 FSMEFSHY 672 E Y Sbjct: 603 CLTELKGY 610
>PF06291#Lambda prophage Bor protein Length = 102 Score = 26.5 bits (58), Expect = 0.024 Identities = 11/29 (37%), Positives = 15/29 (51%) Query: 1 MRKILTLTALLVAITGCSGQQTDTNAAPV 29 M+K+L AL + ITGC+ Q P Sbjct: 6 MKKMLFSAALAMLITGCAQQTFTVGNKPT 34
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 29.5 bits (66), Expect = 0.042 Identities = 21/75 (28%), Positives = 31/75 (41%), Gaps = 14/75 (18%) Query: 143 KGAKGNNIFNDAIVSCESLNLTGSSTIDGYDSRKGAYGDSFNN----AQGNNQLNKHGKG 198 G+K +IF+ A G I+G D YGD N+ G++QL G G Sbjct: 732 FGSKFTDIFHGA---------DGDDLIEGNDGNDRLYGDKGNDTLSGGNGDDQLYG-GDG 781 Query: 199 NVTTVEPNADVTLSG 213 N + + L+G Sbjct: 782 NDKLIGVAGNNYLNG 796
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 31.4 bits (71), Expect = 0.001 Identities = 17/55 (30%), Positives = 29/55 (52%), Gaps = 6/55 (10%) Query: 17 RQSGFSLSELMIAMV-LGLIIMIAVINFF-----APLKATVEESKRLENAADALR 65 +Q GF+L E+M+ +V +G++ + V N A + V + LENA D + Sbjct: 6 KQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK 60
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 35.6 bits (82), Expect = 2e-05 Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 7/48 (14%) Query: 8 GFTLVELMVTVAIISILGSLALPSY-------RDVMAREQLTAAANEL 48 GFTL+E+MV + II +L SL +P+ A + A N L Sbjct: 9 GFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENAL 56
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 48.7 bits (116), Expect = 2e-10 Identities = 18/64 (28%), Positives = 35/64 (54%) Query: 8 EKGFTLIELMIVVAIIGILAAIAIPSFSEYLKQGRRFDAQQYLMTSVQALERNYSRQGKY 67 ++GFTL+E+M+V+ IIG+LA++ +P+ ++ + A ++ AL+ Y Sbjct: 7 QRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDNHHY 66 Query: 68 PAAQ 71 P Sbjct: 67 PTTN 70
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 72.2 bits (177), Expect = 7e-15 Identities = 24/141 (17%), Positives = 52/141 (36%), Gaps = 13/141 (9%) Query: 1286 SVLVVDDNATARDIMCTTLESMGFRVDTVRSGEEAISRCLLQAYEVALIDWKMPNMDGLE 1345 ++LV DD+A R ++ L G+ V + ++ + D MP+ + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 1346 TARQIQLQAQSQSQSQSQPQSHPQPKILMVSAHADHEFLTQIEQLALAGYISKPISASRL 1405 +I+ ++ P +L++SA + + Y+ KP + L Sbjct: 65 LLPRIK-------------KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTEL 111 Query: 1406 LDGIMNAIGREGILPVRRRTE 1426 + I A+ P + + Sbjct: 112 IGIIGRALAEPKRRPSKLEDD 132 Score = 71.4 bits (175), Expect = 1e-14 Identities = 29/134 (21%), Positives = 55/134 (41%), Gaps = 2/134 (1%) Query: 1436 LQGKRILLVEDNEMNLEVASEFLEQVGIILSIATNGQIALDKLSQQHFDLVLMDCQMPVM 1495 + G IL+ +D+ V ++ L + G + I +N ++ DLV+ D MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 1496 DGYQATQAIRKRPELANLPVVAMTANAMAGDRDMCIRAGMNDHIAKPIEVNVLYQTLLKY 1555 + + I+K +LPV+ M+A G D++ KP ++ L + + Sbjct: 61 NAFDLLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 1556 LAPASETVAVVTSA 1569 LA + + Sbjct: 119 LAEPKRRPSKLEDD 132
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 83.3 bits (206), Expect = 7e-20 Identities = 38/160 (23%), Positives = 63/160 (39%), Gaps = 8/160 (5%) Query: 1 MEKATILVVDDTPENIDILIGILGD-DYKVKVAIDGPRALALVAKSRPDLILLDVMMPGM 59 M ATILV DD +L L Y V++ + +A DL++ DV+MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 60 NGYEVCKLLKQ-DPLTSHIPIIFVTALSESSDEAQGFALGAVDYITKPVSAPVVKARVKT 118 N +++ +K+ P +P++ ++A + + GA DY+ KP + + Sbjct: 61 NAFDLLPRIKKARP---DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117 Query: 119 HLALY--DQKRLLEQQVKIRTHELEETRF-EIIRRLGRAA 155 LA +L + EI R L R Sbjct: 118 ALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLM 157
>PHPHLIPASEA1#Bacterial phospholipase A1 protein signature. Length = 289 Score = 217 bits (553), Expect = 1e-71 Identities = 102/303 (33%), Positives = 156/303 (51%), Gaps = 26/303 (8%) Query: 3 RLYSGIAMAGLLACTSINAEESLVEGRVKDE-----------LATAELPFVITPHKVNYI 51 R G + + ++ A+E+ V+ V D L + PF + P+ NY+ Sbjct: 2 RTLQGWLLPVFMLPMAVYAQEATVK-EVHDAPAVRGSIIANMLQEHDNPFTLYPYDTNYL 60 Query: 52 LPATYSPDPNMAPFAEDALINPYTLDEFEAKFQISFKFPIWYNVFGDNGHLFFAYTNQSY 111 + S ++ A + + E KFQ+S FP+W + G N L +YT +S+ Sbjct: 61 IYTQTS---DLNKEAIASYDWAENARKDEVKFQLSLAFPLWRGILGPNSVLGASYTQKSW 117 Query: 112 WQVYNKDTSSPFRETNHEPEVFMLFNNDWKIGSVTNSFWGIGAVHQSNGKSGPLSRSWNR 171 WQ+ N + SSPFRETN+EP++F+ F D++ T +G H SNG+S P SRSWNR Sbjct: 118 WQLSNSEESSPFRETNYEPQLFLGFATDYRFAGWTLRDVEMGYNHDSNGRSDPTSRSWNR 177 Query: 172 LYATMIFDAGPLAFSTKVWWRIPEDEKTDPHQARGDDNPNIDDYIGRAEFIGVYGIDEHR 231 LY ++ + G K W+ + DDNP+I Y+G + Y + + Sbjct: 178 LYTRLMAENGNWLVEVKPWYVVGNT----------DDNPDITKYMGYYQLKIGYHLGDAV 227 Query: 232 FTLTLKTNLEDIDRGSAELTWSYPIVGNLRLYTQYFNGYGESLIDYNYHNQRIGIGISLN 291 + + N G AEL SYPI ++RLYTQ ++GYGESLIDYN++ R+G+G+ LN Sbjct: 228 LSAKGQYNWNT-GYGGAELGLSYPITKHVRLYTQVYSGYGESLIDYNFNQTRVGVGVMLN 286 Query: 292 DIL 294 D+ Sbjct: 287 DLF 289
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 67.2 bits (164), Expect = 6e-14 Identities = 46/155 (29%), Positives = 70/155 (45%), Gaps = 17/155 (10%) Query: 41 VDDGKSTLIGRLLHDSAQIYEDQLASLKSDSAKMGTTGEAIDLALLVDGLQAEREQGITI 100 VD GK+TL LL++S I +L S+ + + D ER++GITI Sbjct: 12 VDAGKTTLTESLLYNSGAI--TELGSVDKGTTRT-------------DNTLLERQRGITI 56 Query: 101 DVAYRYFSSDKRKFIIADTPGHEQYTRNMATGASTCDLAVILVDARYGVQTQTKRHAFIA 160 F + K I DTPGH + + S D A++L+ A+ GVQ QT+ Sbjct: 57 QTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHAL 116 Query: 161 SLLGIRHFVVAVNKMDLLGFD-EQVFNRIRADFTD 194 +GI + +NK+D G D V+ I+ + Sbjct: 117 RKMGIPT-IFFINKIDQNGIDLSTVYQDIKEKLSA 150
>PF06580#Sensor histidine kinase Length = 349 Score = 52.6 bits (126), Expect = 2e-09 Identities = 30/125 (24%), Positives = 45/125 (36%), Gaps = 21/125 (16%) Query: 497 ELEIDIDANIEMNSYPGALGQSLENFVTNAITHAFEGR-GNGQIKISAKMIEDQIVEITV 555 + E I+ I P L Q+L V N I H G+I + ++ V + V Sbjct: 241 QFENQINPAIMDVQVPPMLVQTL---VENGIKHGIAQLPQGGKILLKGTK-DNGTVTLEV 296 Query: 556 SDNGIGMSAETMKQIFDPFFTTRRGNGGTGLGLHLTYQLVSQLLGGK--ITVSSKLGKGS 613 + G T + TG GL + + L G + I +S K GK + Sbjct: 297 ENTGSLALKNTKE--------------STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVN 342 Query: 614 VFSLI 618 LI Sbjct: 343 AMVLI 347
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 44.8 bits (106), Expect = 1e-06 Identities = 26/153 (16%), Positives = 54/153 (35%), Gaps = 15/153 (9%) Query: 27 KILTVDDDSNFQRSTAFALSTLKVLDCKIELSQAFSYAEACQVLTKENDFAIALVDVVME 86 IL DDD+ + ALS ++ + A + + D + + DVVM Sbjct: 5 TILVADDDAAIRTVLNQALS-----RAGYDVRITSNAATLWRWIAAG-DGDLVVTDVVMP 58 Query: 87 TEDAGLRLVRAIREVLGNEKIRIILLTGQPGMAPIFDVMRDYDINDYWTKS---ELSADR 143 E+ L+ I++ + +++++ Q DY K Sbjct: 59 DEN-AFDLLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEK-GAYDYLPKPFDLTELIGI 114 Query: 144 LQTILTTNLRSYQQISSIANAKRGLQLIAESSG 176 + L R ++ +++ G+ L+ S+ Sbjct: 115 IGRALAEPKRRPSKLE--DDSQDGMPLVGRSAA 145
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 34.8 bits (80), Expect = 5e-04 Identities = 32/143 (22%), Positives = 48/143 (33%), Gaps = 12/143 (8%) Query: 249 VVNLLFAPAIGRFIGRIGERNALTVEYVGLIIVFISYALVEQAHMAAALY---VIDHLLF 305 ++ AP +G R G R L V L + YA++ A LY ++ + Sbjct: 54 LMQFACAPVLGALSDRFGRRPVLLV---SLAGAAVDYAIMATAPFLWVLYIGRIVAGITG 110 Query: 306 AMAIAMKTYFQKIADSKDIAAT---MSVSFTINHIAAVIIPVLLGLLWLTDPALVFYIGA 362 A Y I D + A MS F +A PVL GL+ P F+ A Sbjct: 111 ATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAG---PVLGGLMGGFSPHAPFFAAA 167 Query: 363 GFAVCSLILALNVPRHPEPGNET 385 + + + G Sbjct: 168 ALNGLNFLTGCFLLPESHKGERR 190 Score = 30.9 bits (70), Expect = 0.009 Identities = 24/151 (15%), Positives = 58/151 (38%), Gaps = 11/151 (7%) Query: 204 YWLYYLLTFFSGARRQIFMVFAGFMMVEKFGYSVSEITALFLINYVVNLLF-APAIGRFI 262 +++++ ++++F ++F + + I +++ L A G Sbjct: 216 MAVFFIMQLVGQVPAALWVIFG----EDRFHWDATTIGISLAAFGILHSLAQAMITGPVA 271 Query: 263 GRIGERNALTVEYVGLIIVFISYALVEQAHMAAALYVIDHLLFAMAIAM---KTYFQKIA 319 R+GER AL + + +I A + MA + V LL + I M + + Sbjct: 272 ARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMV---LLASGGIGMPALQAMLSRQV 328 Query: 320 DSKDIAATMSVSFTINHIAAVIIPVLLGLLW 350 D + + + +++ P+L ++ Sbjct: 329 DEERQGQLQGSLAALTSLTSIVGPLLFTAIY 359
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 34.0 bits (78), Expect = 0.002 Identities = 22/144 (15%), Positives = 44/144 (30%), Gaps = 18/144 (12%) Query: 122 QINQINEQLFAVENHPDIPRLSTELETEQAQAQAELDAHRQVMIDSRQSRKAQRNQLAA- 180 + I EQ +N + E + +AE + + ++++L Sbjct: 187 LTSLIKEQFSTWQNQ------KYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDF 240 Query: 181 -QLAAN---PTDETL-RENAITEAKLS-QESISEKNQLRDIKRYWDERIHTISQ-----A 229 L L +EN EA + S+ Q+ E ++Q Sbjct: 241 SSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEI 300 Query: 230 LSQLTDERDALRQQRKRLSAALQQ 253 L +L D + L+ ++ Sbjct: 301 LDKLRQTTDNIGLLTLELAKNEER 324
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 31.3 bits (71), Expect = 0.005 Identities = 10/28 (35%), Positives = 13/28 (46%), Gaps = 2/28 (7%) Query: 17 GCGELGKEVAIELQRLGVEVIGVD--RY 42 G L K V LQ+ G V+G +Y Sbjct: 62 GWATLDKAVGGILQQQGWPVVGWSSLKY 89
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 61.0 bits (148), Expect = 2e-12 Identities = 52/320 (16%), Positives = 98/320 (30%), Gaps = 80/320 (25%) Query: 66 ITPAVKGLVSRVEVQPNTPVKQGDVLFRIDPIPFEAVVK--------------RKRAALV 111 I P +V + V+ V++GDVL ++ + EA R + Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSR 158 Query: 112 AAEL--------------------EVPQLAAALESAKANVER----VNADKDRNKSAYER 147 + EL EV +L + ++ + + + D+ ++ Sbjct: 159 SIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLT 218 Query: 148 YESGHRKGGANSPFTALELDNKRQL----------YLASEAQLTAARSE----------- 186 + + S LD+ L L E + A +E Sbjct: 219 VLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQI 278 Query: 187 -----ELRMRLA-----YESNIDG----VNTKVAGLQGDLASALYDLEQTVVRAPADGIV 232 + +++ I + L +LA + +V+RAP V Sbjct: 279 ESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKV 338 Query: 233 TQMALR-PGAMAVPLPLRPVMSFIPDEQRYFAGAFWQNSLL-RLKEGDEAEIILDAAPGK 290 Q+ + G V +M +P++ A QN + + G A I ++A P Sbjct: 339 QQLKVHTEG--GVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYT 396 Query: 291 ---VFKGKVAKVLPAMAEGE 307 GKV + E + Sbjct: 397 RYGYLVGKVKNINLDAIEDQ 416
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.4 bits (66), Expect = 0.041 Identities = 12/49 (24%), Positives = 24/49 (48%), Gaps = 5/49 (10%) Query: 266 VQQAKALDAPKGILLLGVQGSGKSLAAKAV---AGVWQRPLLRLDMAAL 311 + + D +++ G G+GK L A+A+ P + ++MAA+ Sbjct: 153 LARLMQTDLT--LMITGESGTGKELVARALHDYGKRRNGPFVAINMAAI 199
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.9 bits (64), Expect = 0.044 Identities = 11/38 (28%), Positives = 17/38 (44%), Gaps = 7/38 (18%) Query: 30 MIGLLGPSGSGKTTLLRIIAGLEGADSGNIYFGDRDVT 67 + L G G GK+TL+ + GL+ +F D Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLD-------FFSDTHFD 628
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 69.9 bits (171), Expect = 3e-16 Identities = 20/112 (17%), Positives = 51/112 (45%), Gaps = 2/112 (1%) Query: 12 LVEDQQLVRQGIASLLAISDNIRVLWQAEDGQDALSQLDNNPVDVLLSDIRMPNLDGIAM 71 + +D +R + L+ + V + + D++++D+ MP+ + + Sbjct: 8 VADDDAAIRTVLNQALSRAG-YDVR-ITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 72 LKQIRQSANSLPVIMLTTFDDSELFLNSLQAGANGFLLKDVSLDKLLHAIET 123 L +I+++ LPV++++ + + + + GA +L K L +L+ I Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>PF06580#Sensor histidine kinase Length = 349 Score = 32.9 bits (75), Expect = 0.002 Identities = 19/101 (18%), Positives = 44/101 (43%), Gaps = 15/101 (14%) Query: 291 LVLQEGISNAVRHG-----KANQLQLSMEDSQNALVLQLSDNGVGLTRVAARNASAKSGT 345 +++Q + N ++HG + ++ L + L++ + G + + K T Sbjct: 258 MLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALK------NTKEST 311 Query: 346 GLYGTGLSGMQERLQP-FNGKVQLRANDLAPGCQLTLTLPA 385 GTGL ++ERLQ + + Q++ ++ + +P Sbjct: 312 ---GTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIPG 349
>FLAGELLIN#Flagellin signature. Length = 507 Score = 29.6 bits (66), Expect = 0.033 Identities = 30/256 (11%), Positives = 73/256 (28%), Gaps = 14/256 (5%) Query: 74 AHDISVQTSKIAIGSAEVSHFIDLLNKSIESNGEHASAIAVAAGQLSHTTAQLGDNAADI 133 K+ + +A D + + + + A G Sbjct: 217 DTTAPTVPDKVYVNAANGQLTTDDAENNTAVDLFKTTKSTAGTAE---AKAIAGAIKGGK 273 Query: 134 LGQAQEAERVSVQGRSQAQKG-----VSAIRSLSTDIDTAAEQVQALKSRAEEIQKITEV 188 G + + V+ ++ + I + A A A +Q V Sbjct: 274 EGDTFDYKGVTFTIDTKTGNDGNGKVSTTINGEKVTLTVADITAGAANVDAATLQSSKNV 333 Query: 189 INSVAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAGKTAGATQDIGKMLLEIRSE 248 SV E+A+ + AV + ++ G A K+ L ++ Sbjct: 334 YTSVVNGQFTFDDKTKNESAKLSDLEANNAVKGESKITVNGAEYTANAAGDKVTLAGKTM 393 Query: 249 TDKTSGLMERVVTQTADVVA------AMGELDAHFTEISASVTQSAHALGDMEDSLKQYN 302 + + A + +D+ +++ A + + ++ Sbjct: 394 FIDKTASGVSTLINEDAAAAKKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLG 453 Query: 303 NTTNDISRSVTQIRDS 318 NT +++ + ++I D+ Sbjct: 454 NTVTNLNSARSRIEDA 469
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 59.6 bits (144), Expect = 2e-13 Identities = 30/167 (17%), Positives = 62/167 (37%), Gaps = 3/167 (1%) Query: 2 RNAEFDREQVLRGAMAAFMHKGYTKTSMQDLTQATGLHPGSIYCAFTNKRGLLIAAIEQY 61 + A+ R+ +L A+ F +G + TS+ ++ +A G+ G+IY F +K L E Sbjct: 7 QEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELS 66 Query: 62 QLDRNAQFNSLFAK-SENVLTNLKTYLDHIVAECLSCDSAQACLLTKALNEVAEQDVEIR 120 + + AK + L+ L+ L H++ ++ + + + ++ + Sbjct: 67 ESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVV 126 Query: 121 D-IINQYLQSWQQALTQQFTSAAEQGLLEGHRSDEQRAQYFMMGIYG 166 + Q E +L +RA M G Sbjct: 127 QQAQRNLCLESYDRIEQTLKHCIEAKMLPADL-MTRRAAIIMRGYIS 172
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.6 bits (69), Expect = 0.028 Identities = 12/39 (30%), Positives = 17/39 (43%), Gaps = 6/39 (15%) Query: 339 LFGYVENATFRGTVFTDFSLIRPGSLHKANGGVLLMDAV 377 LFG+ + A FT G +A GG L +D + Sbjct: 208 LFGHEKGA------FTGAQTRSTGRFEQAEGGTLFLDEI 240
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 56.9 bits (137), Expect = 2e-12 Identities = 31/163 (19%), Positives = 63/163 (38%), Gaps = 5/163 (3%) Query: 8 DRREKLI-LAMELFWQKGFAETSISDLVGHLGINRFSLYNSFGDKQKLYRECLSFYLDNY 66 + R+ ++ +A+ LF Q+G + TS+ ++ G+ R ++Y F DK L+ E N Sbjct: 11 ETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNI 70 Query: 67 SFGASDTLLHEKAGLAE-IAAYLARFVALQREQKYGCFMQNAVLEKSL--DDESVLQECQ 123 + + L + ++ + + K + +V+Q+ Q Sbjct: 71 GELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQ 130 Query: 124 RLFCRLQTS-FTQVLQDCQARGELLANVQPHQVAAFLVLQLQG 165 R C Q L+ C L A++ + A + + G Sbjct: 131 RNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISG 173
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 27.6 bits (61), Expect = 0.046 Identities = 13/46 (28%), Positives = 22/46 (47%), Gaps = 2/46 (4%) Query: 50 PALQFIEQMQPSILALSPRLTAVPKKVGGSLMRPQRDSRFSKDKTP 95 P L+ + +M+PS + S P+ + + + P R FS K P Sbjct: 87 PNLELLTEMKPSFMVWSAGYGPSPEML--ARIAPGRGFNFSDGKQP 130
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 31.0 bits (70), Expect = 0.008 Identities = 35/192 (18%), Positives = 68/192 (35%), Gaps = 9/192 (4%) Query: 36 LPSIQEDISLSFTLASMLTLLPVLAMGLGCFAGFSIAKRLGFNTVMTGSLLLLIVATAMR 95 LP I D + + + +L +G ++ +LG ++ +++ + + Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 96 FWAMD-ASWLICSALLAGIGIA-LIQTIMPAMIKLNFGERVPLMMGLYVTAIMGGAALAA 153 F S LI + + G G A +M + + E GL + + G + Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGV-- 154 Query: 154 SSAPFIGMNLGWRAGLGHWTWLGVVALALWMMVKHNAALPNQTAEQTVQLSFWRFRRSWL 213 P IG G A HW++L ++ + + V L + + Sbjct: 155 --GPAIG---GMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSV 209 Query: 214 LAIFFALGTSCY 225 +FF L T+ Y Sbjct: 210 GIVFFMLFTTSY 221
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 35.2 bits (81), Expect = 8e-04 Identities = 20/123 (16%), Positives = 43/123 (34%), Gaps = 8/123 (6%) Query: 42 IETLAVPVQKQSNSLQLVLLKMSRLATLAHSQQDTAALTKSQQAFTALQKKYQSIENELT 101 T+ + + N ++ ++ ++L H Q ++ A + KY NEL Sbjct: 216 RLTVLARINRYENLSRVEKSRLDDFSSLLHKQ------AIAKHAVLEQENKYVEAVNELR 269 Query: 102 ERVADQSKMQTSLHEAQARYQAYLQQSQAMFSAKLANEQAKQQYQQLFQRFNDAKTNASN 161 + ++++ + A+ YQ Q + KL Q L + Sbjct: 270 VYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLR--QTTDNIGLLTLELAKNEERQQA 327 Query: 162 AMI 164 ++I Sbjct: 328 SVI 330
>PF07824#Type III secretion chaperone Length = 120 Score = 27.6 bits (61), Expect = 0.018 Identities = 14/54 (25%), Positives = 23/54 (42%) Query: 80 AIGLDLTKRDLQSKLKAKGLPWERAKAFDGAALFSPFVAIDDAEAPLHFTLSIN 133 A+G+ D Q+ + + K D L PF A+ + L + LS+N Sbjct: 11 ALGIPSIDTDDQAIMLDDDVLIYIEKEGDSINLLCPFCALPENINDLIYALSLN 64
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.8 bits (67), Expect = 0.001 Identities = 12/56 (21%), Positives = 22/56 (39%), Gaps = 3/56 (5%) Query: 19 FKPNGIPMTQLEQVPLAEDEIEAMRLVDLL---GMQQQEAAKSMGVSRQTLANLVK 71 F G + E+E ++ L Q +AA +G++R TL ++ Sbjct: 416 FASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIR 471
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.2 bits (68), Expect = 0.018 Identities = 15/70 (21%), Positives = 29/70 (41%), Gaps = 13/70 (18%) Query: 64 KLPTPHELRAHLDDYVIGQDRAKKVLSVAVYNHYKRLKNASPKDGIELGKSNILLIGPTG 123 + P+ E + ++G+ S A+ Y+ L D +++ G +G Sbjct: 124 RRPSKLEDDSQDGMPLVGR-------SAAMQEIYRVLARLMQTD------LTLMITGESG 170 Query: 124 SGKTLLAETL 133 +GK L+A L Sbjct: 171 TGKELVARAL 180
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 34.4 bits (79), Expect = 0.002 Identities = 45/211 (21%), Positives = 76/211 (36%), Gaps = 37/211 (17%) Query: 262 NMPAEAKEKALAELNKLRMMSP---MSAEATV---VRSY----VDWMTSVPWSQRSKIKR 311 MP E L + K R P MSA+ T +++ D++ P+ I Sbjct: 56 VMPDENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPK-PFDLTELIGI 114 Query: 312 D---------LAKAQEVLDTDHFGLEKVKERILEYLAVQSRVRQLKGPILCLVGPPGVGK 362 E D L + E V +R+ Q ++ + G G GK Sbjct: 115 IGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLM-ITGESGTGK 173 Query: 363 TSLGQSIAKATGRK---YVRVALGGVRD---EAEIRGHRRTYIGSMPGKVIQKMAKVGVK 416 + +++ R+ +V + + + E+E+ GH + G+ G + + Sbjct: 174 ELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEK---GAFTGAQTRSTGRFEQA 230 Query: 417 N--PLFLLDEIDKMSSDMRGDPASALLEVLD 445 LFL DEI M D + + LL VL Sbjct: 231 EGGTLFL-DEIGDMPMDAQ----TRLLRVLQ 256
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 119 bits (300), Expect = 4e-39 Identities = 53/88 (60%), Positives = 69/88 (78%) Query: 2 NKSELIEKIASGADISKAAAGRALDSFIAAVTEGLKEGDKISLVGFGTFEVRERAERTGR 61 NK +LI K+A +++K + A+D+ +AV+ L +G+K+ L+GFG FEVRERA R GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 62 NPQTGEEIKIAAAKIPAFKAGKALKDAV 89 NPQTGEEIKI A+K+PAFKAGKALKDAV Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAV 90
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.022 Identities = 13/28 (46%), Positives = 16/28 (57%) Query: 42 TLAIVGEAGSGKSTLARILVGAEPRSGG 69 TL I GE+G+GK +AR L R G Sbjct: 162 TLMITGESGTGKELVARALHDYGKRRNG 189
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.2 bits (68), Expect = 0.011 Identities = 9/16 (56%), Positives = 14/16 (87%) Query: 38 LVGESGSGRSLLARAI 53 + GESG+G+ L+ARA+ Sbjct: 165 ITGESGTGKELVARAL 180
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.5 bits (157), Expect = 4e-14 Identities = 29/136 (21%), Positives = 53/136 (38%), Gaps = 7/136 (5%) Query: 3 RIAIVEDEAAIRENYKDVLQQHGYSVQTYADRPSAMLAFNTRLPDLAIIDIGLGNEIDGG 62 I + +D+AAIR L + GY V+ ++ + DL + D+ + +E Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE--NA 62 Query: 63 FMLCQSLRAMSSTLPIIFLTARDSDFDTVCGLRLGADDYLSKEVSFPHLTARLAALFRRS 122 F L ++ LP++ ++A+++ + GA DYL K L Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGI-----IGR 117 Query: 123 ELAASQTAQENLLERG 138 LA + L + Sbjct: 118 ALAEPKRRPSKLEDDS 133
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 65.0 bits (158), Expect = 3e-14 Identities = 28/92 (30%), Positives = 48/92 (52%), Gaps = 2/92 (2%) Query: 154 ELALGLNVQFRTGSSEVESHFLPQLDDVAEVM-NLSP-ELNLELKGYADRRGDVSYNQAL 211 L +V F + ++ LD + + NL P + ++ + GY DR G +YNQ L Sbjct: 214 HFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGL 273 Query: 212 SEQRLLEVRGYLIKQGVAAERMTTQAFGALSP 243 SE+R V YLI +G+ A++++ + G +P Sbjct: 274 SERRAQSVVDYLISKGIPADKISARGMGESNP 305
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 90.0 bits (223), Expect = 1e-25 Identities = 32/148 (21%), Positives = 58/148 (39%), Gaps = 2/148 (1%) Query: 9 LEHFLQRGGSLRMLADVEQSDLNVLYQYALQLMACRDQQGAKRIFYLLMRIEQWNYDYCF 68 +E FL+ GG++ ML ++ L LY A + A ++F L ++ ++ + Sbjct: 15 MESFLKGGGTIAMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFL 74 Query: 69 SLGICCQQLHEHEEAIFCLGRAGMIKVDNPLPAYHAGLSYLALGNHDYAKRSFNASLRWC 128 LG C Q + +++ AI ++ + P +HA L G A+ + Sbjct: 75 GLGACRQAMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQELI 134 Query: 129 EGHPESTGIAASAQRGLA--TLAKENSH 154 E ++ L L KE H Sbjct: 135 ADKTEFKELSTRVSSMLEAIKLKKEMEH 162
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 72.6 bits (178), Expect = 1e-15 Identities = 28/164 (17%), Positives = 65/164 (39%), Gaps = 6/164 (3%) Query: 255 KVLLVDDQQSMVDYFSSLLRSHGLMVKGLSSAEQVLPALEQFEPDLFIFDLYMPEVNGLE 314 +L+ DD ++ + L G V+ S+A + + + DL + D+ MP+ N + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 315 LAKMIRQLDKYTSSPILVLSSDDTMQNKVSIIQAGSDDLISKQTAPSLFVA---QVISRA 371 L I++ P+LV+S+ +T + + G+ D + K + + + ++ Sbjct: 65 LLPRIKKARPDL--PVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 372 QRGHDIRSSASRDSLTGLLNHTQILVAARRCYNVARRINSQVCI 415 +R + L+ + + R + + + I Sbjct: 123 KRRPS-KLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMI 165 Score = 55.2 bits (133), Expect = 4e-10 Identities = 30/135 (22%), Positives = 59/135 (43%), Gaps = 2/135 (1%) Query: 131 HIAIIEDDGNVGAMITKQLREFGFSVQHFLNFTSFLVVQNETPFDLILLDLILPDWTEEA 190 I + +DD + ++ + L G+ V+ N + DL++ D+++PD Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 191 LFEAATEFEKNNTRVFVLSSRGDFDMRLLAIRANVSEYFVKPAETTLLVRKIHQSLKMSE 250 L + + + V V+S++ F + A +Y KP + T L+ I ++L + Sbjct: 65 LLPRIKK-ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 251 KQPLKVLLVDDQQSM 265 ++P L D Q M Sbjct: 124 RRP-SKLEDDSQDGM 137
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 68.7 bits (168), Expect = 7e-15 Identities = 29/118 (24%), Positives = 51/118 (43%), Gaps = 6/118 (5%) Query: 3 IKVLVVDDSALMRSLLGKMIEADPELSLVGQAADAFEAKDLVNQFRPDVITLDIEMPKVD 62 +LV DD A +R++L + + + ++A + D++ D+ MP + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRI--TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 63 GLTFLDRLMKARPTAVVMISSLTEQG-ADATFNALALGAVDFIPKPKLDSPQGIHDYQ 119 L R+ KARP V++ ++ Q A GA D++PKP D + I Sbjct: 62 AFDLLPRIKKARPDLPVLV--MSAQNTFMTAIKASEKGAYDYLPKP-FDLTELIGIIG 116
>PF06580#Sensor histidine kinase Length = 349 Score = 43.7 bits (103), Expect = 2e-06 Identities = 24/151 (15%), Positives = 51/151 (33%), Gaps = 52/151 (34%) Query: 440 EIDKGMIEKLVDPLT--HLVRNSLDHGIEKPEKRLAAGKSEVGVLSLKASQRGGNIVIAV 497 +I+ +++ V P+ LV N + HGI + + G + LK ++ G + + V Sbjct: 245 QINPAIMDVQVPPMLVQTLVENGIKHGIAQ--------LPQGGKILLKGTKDNGTVTLEV 296 Query: 498 HDNGAGLNRERIIQKARESGLQVADNSSDKQIWQLIFAAGFSTAVEVTDVSGRGVGMDVV 557 + G+ + G G+ V Sbjct: 297 ENTGSLALKNTK--------------------------------------ESTGTGLQNV 318 Query: 558 RRNIEALGG---RIDIESTEGQGSTFEIQLP 585 R ++ L G +I + +G+ + + +P Sbjct: 319 RERLQMLYGTEAQIKLSEKQGKVNAM-VLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 87.6 bits (217), Expect = 1e-23 Identities = 29/122 (23%), Positives = 53/122 (43%), Gaps = 3/122 (2%) Query: 1 MSK-KILIVDDSAAIRQMVEATLKSANYQVVLAKDGREALDICNGQKFDFILTDQNMPRM 59 M+ IL+ DD AAIR ++ L A Y V + + D ++TD MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 60 DGLTLIKSLRAMSAFMRTPIIMLTTEAGDDMKAQGKAAGATGWMVKPFDPQKLLAITAKV 119 + L+ ++ P+++++ + + GA ++ KPFD +L+ I + Sbjct: 61 NAFDLLPRIKKAR--PDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 120 LG 121 L Sbjct: 119 LA 120
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 65.2 bits (159), Expect = 3e-13 Identities = 27/122 (22%), Positives = 55/122 (45%) Query: 11 ILVVDDDAIASQRISDFIHSKGYNVIVCNDLEEVFFEITQNTVDLILINYWLKDGTALAL 70 ILV DDDA ++ + GY+V + ++ ++ I DL++ + + D A L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 71 LNKLNEEKQETPVIVMSETKESQNVLACFSMGVLDFVVKPINVEIFWYKVECLLSRVQLQ 130 L ++ + + + PV+VMS + G D++ KP ++ + L+ + + Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRR 125 Query: 131 HK 132 Sbjct: 126 PS 127
>PF04183#IucA / IucC family Length = 580 Score = 625 bits (1614), Expect = 0.0 Identities = 168/593 (28%), Positives = 291/593 (49%), Gaps = 22/593 (3%) Query: 42 LTPAYWQAANRHLVKKILCEFTHEKIITPTLYGQKAGLNHYELRLKNSTYYFSARHYQLD 101 + W NR LV K+L E +E++ + G + Y + L + + F A Sbjct: 1 MNHKDWDLVNRRLVAKMLSELEYEQVFHA----ESQGDDRYCINLPGAQWRFIAERGIWG 56 Query: 102 HLAIDADSIRVSVAGQEQALDAMSLIISLKNDLGISETLLPTYLEEITSTLYSKAYKL-A 160 L IDA ++R ++ + A +L++ LK L +S+ + +++++ +TL L A Sbjct: 57 WLWIDAQTLRC----ADEPVLAQTLLMQLKQVLSMSDATVAEHMQDLYATLLGDLQLLKA 112 Query: 161 HQAIPAATLARADYQSIEAGMTEGHPVFIANNGRIGFDMQDYRQFAPESAMPMQLVWLGV 220 + + A+ L + ++ + GHP F+ N GR G+ + ++APE A +L WL V Sbjct: 113 RRGLSASDLINLNADRLQC-LLSGHPKFVFNKGRRGWGKEALERYAPEYANTFRLHWLAV 171 Query: 221 RKSKTTFAALENLSHDALLKEELG-QQFTDFQQRLKAQQHDPQDFYFMPVHPWQWREKIA 279 ++ + + LL + Q+F F Q + D ++ +PVHPWQW++KIA Sbjct: 172 KREHMIWRCDNEMDIHQLLTAAMDPQEFARFSQVWQENGLD-HNWLPLPVHPWQWQQKIA 230 Query: 280 RVFAGDIARGDLVYLGEGSQQYQVQQSIRTFFNLSSPQKCYVKTALSILNMGFMRGLSPL 339 F D A G +V LGE Q+ QQS+RT N S +K L+I N RG+ Sbjct: 231 TDFIADFAEGRMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGR 290 Query: 340 YMSCTPQINAWVANLVESDPYFTQQGFVILKEIAAIGYHHHYYEQALTQDSAYKKMLSAL 399 Y++ P + W+ + +D Q G VIL E AA H Y Y++ML + Sbjct: 291 YIAAGPLASRWLQQVFATDATLVQSGAVILGEPAAGYVSHEGYAALARAPYRYQEMLGVI 350 Query: 400 WRESPLPHIAPKQNLMTMAALLHTDHEDKALISALITASGLPAKDWLSRYLNLYLSPLLH 459 WRE+P + P ++ + MA L+ D ++ L A I SGL A+ WL++ + + PL H Sbjct: 351 WRENPCRWLKPDESPVLMATLMECDENNQPLAGAYIDRSGLDAETWLTQLFRVVVVPLYH 410 Query: 460 AFFAYDLVFMPHGENLILVLDEYVPVKILMKDIGEEVAVLNGTSP----LPDDVKRLAVS 515 Y + + HG+N+ L + E VP ++L+KD ++ ++ P LP +V+ + Sbjct: 411 LLCRYGVALIAHGQNITLAMKEGVPQRVLLKDFQGDMRLVKEEFPEMDSLPQEVRDVTSR 470 Query: 516 LEEEMKLNYILLDIFDCIFRYLAPLLDEQTSVSESQFWELVADNVRDYQAQHPHLAAKFA 575 L + ++ + F + R+++PL+ + V E +F++L+A + DY +HP ++ +FA Sbjct: 471 LSADYLIHDLQTGHFVTVLRFISPLMV-RLGVPERRFYQLLAAVLSDYMKKHPQMSERFA 529 Query: 576 QYDLFKDSFVRTCLNRIQLNNNQQMIDLADREKNL-RFAGGIDNPLAAFRQSH 627 + LF+ +R LN ++L DL + L + + NPL Q + Sbjct: 530 LFSLFRPQIIRVVLNPVKL----TWPDLDGGSRMLPNYLEDLQNPLWLVTQEY 578
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 30.4 bits (68), Expect = 0.034 Identities = 31/130 (23%), Positives = 42/130 (32%), Gaps = 21/130 (16%) Query: 231 DSGSVRGRVVAAYQDKDSFQDRYEQQRTTLYGIVETDIGDSTLFTLGVDYQDATPSGTMS 290 D+G GR A Q D+ R Q + G F LG D+ A G Sbjct: 645 DAGGAWGRGFAQRQQLDNRAGRRFDQ--KVAG-----------FELGADHAVAVAGGRWH 691 Query: 291 GGLPLFYSDGSRTNYDRATSTAPDWGSAHTQGLNTFASLEHRFDNGWNLKGTYTYGDNSL 350 G Y+ G R G HT ++ + D+G+ L T Sbjct: 692 LGGLAGYTRGDRG--------FTGDGGGHTDSVHVGGYATYIADSGFYLDATLRASRLEN 743 Query: 351 KFDVLWATGY 360 F V + GY Sbjct: 744 DFKVAGSDGY 753
>2FE2SRDCTASE#Ferric iron reductase signature. Length = 262 Score = 111 bits (279), Expect = 1e-30 Identities = 76/322 (23%), Positives = 113/322 (35%), Gaps = 108/322 (33%) Query: 45 LSATSSPTGLSFDEWSCADTYQTLLARFAIAHPSAETLTETKTENETETDKTAATSQTPA 104 L + ++ +WS + +LLA + Sbjct: 46 LDEPAPLNAMTLAQWSSPNVLSSLLAVY-------------------------------- 73 Query: 105 FASKSVLVSKNAGANRKDTRKALYSLWGQWYFGLLVPPMMEWIFNAPQTDLKSIHWQPQS 164 + R++ K L SLW QWY GL+VPP+M + + + P+ Sbjct: 74 ---SDHIYRNQPMMIREN--KPLISLWAQWYIGLMVPPLMLALLTQEKA----LDVSPEH 124 Query: 165 IFMQLHPSGRVAKFEFNIAKHQPNTALTFKKHHGIEPLCQINTKPSIKIDTEEHSPLSPY 224 + H +GRVA F ++ + + T HSP Sbjct: 125 FHAEFHETGRVACFWVDVCEDKNAT---------------------------PHSPQHRM 157 Query: 225 KPPVDKELVLQGFILNLLQPSVERLLTLSPVPVKLYWSHLGYLIHWYLGELG--LTEQHS 282 + I L P V+ L + KL WS+ GYLI+WYL E+ L E Sbjct: 158 ----------ETLISQALVPVVQALEATGEINGKLIWSNTGYLINWYLTEMKQLLGEATV 207 Query: 283 QQLKQALFRRTTFLDGSTNPLYNSINLLIEPERDSATPNTVARIVTSTASRSKPSPKIHC 342 + L+ ALF T +G NPL+ ++ L RD Sbjct: 208 ESLRHALFFEKTLTNGEDNPLWRTVVL-----RDGLL----------------------- 239 Query: 343 IRRTCCLRYQLANTGQCHDCPL 364 +RRTCC RY+L + QC DC L Sbjct: 240 VRRTCCQRYRLPDVQQCGDCTL 261
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 25.4 bits (55), Expect = 0.042 Identities = 9/44 (20%), Positives = 14/44 (31%) Query: 54 AGFSGSLVVADFESLVAAKHWADADPYIEAGVYKSVVVKPFKRV 97 G GS+ + + A W +P V V +V Sbjct: 279 IGGLGSVAGFEKNTREAVDRWIQENPNAAETVEAVFNVAAAAKV 322
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 30.1 bits (67), Expect = 0.038 Identities = 47/204 (23%), Positives = 74/204 (36%), Gaps = 29/204 (14%) Query: 157 RTNLGLTPEAVRLVEVYHQRFIMAGAKLTDEQKVKIRALNEEQSTLTNE--FSQRLLRLT 214 +T LG EA L E ++ A + K +A N+ QS + ++Q + Sbjct: 130 QTALGEAQEATDLYEASIKKTDTAKSVYDAATKKLTQAQNKLQSLDPADPGYAQAEAAVE 189 Query: 215 KEIAVVVESKNELAGLTDSDITSAANDAKAAGHDGKYLINITNTTRQPVLASLENRELRQ 274 + E+K L TD+ A DAKA ++ T Sbjct: 190 QAGKEATEAKEALDKATDA-TVKAGTDAKAKAEKADNILTKFQGTAN------------- 235 Query: 275 RIWEASANRGLTGENETASLVSRLAQLRAERAALLGYENWASYRLAPQMAKTPEAVYSMF 334 AS N+ GE + S V+RL L A ++G S L +A +F Sbjct: 236 ---AASQNQVSQGEQDNLSNVARLTMLMAMFIEIVGKNTEES--LQNDLA--------LF 282 Query: 335 GSMVPAVVANTEKEAADIQAMIDK 358 ++ A EK++A+ Q K Sbjct: 283 NALQEGRQAEMEKKSAEFQEETRK 306
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 28.2 bits (62), Expect = 0.010 Identities = 17/77 (22%), Positives = 29/77 (37%), Gaps = 13/77 (16%) Query: 20 ELSVEELRDLADKLDK-------ILVERESMAEEEEQAMAARNAKIEEIRQQMEAVG--- 69 +L E + L +++ I + A E+ A A R A EE +Q A+ Sbjct: 191 KLFTEAISSLQIRMNTLTAAKASIEAAAANKAREQAAAEAKRKA--EEQARQQAAIRAAN 248 Query: 70 -LSIDDLGGVAVKATAK 85 ++ G V A + Sbjct: 249 TYAMPANGSVVATAAGR 265
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 42.4 bits (100), Expect = 8e-06 Identities = 16/29 (55%), Positives = 19/29 (65%) Query: 919 TINPAKQLRVDEFVGSLTPGKMADIVLWN 947 TINPA + +GSL GK AD+VLWN Sbjct: 410 TINPAIAHGLSHEIGSLEVGKRADLVLWN 438 Score = 34.3 bits (79), Expect = 0.003 Identities = 34/124 (27%), Positives = 48/124 (38%), Gaps = 39/124 (31%) Query: 585 IKNATLWTSDKQGILEHADLLMANGRIEKIGQ----------QLSTPSGYQVLDATGKHL 634 I NA + D GI++ AD+ + +GRI IG+ + G +V+ GK + Sbjct: 72 ITNALI--LDHWGIVK-ADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIV 128 Query: 635 TAGIVDEHSHIAINGGTNEGTDAVTSEVRIGDIINPDDISIYRALAGGVTSAQLLHGSAN 694 TAG +D H H I P I AL G+T +L G Sbjct: 129 TAGGMDSHIH----------------------FICPQ--QIEEALMSGLTC--MLGGGTG 162 Query: 695 PIGG 698 P G Sbjct: 163 PAHG 166
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 30.9 bits (69), Expect = 0.012 Identities = 18/59 (30%), Positives = 33/59 (55%), Gaps = 5/59 (8%) Query: 201 PEDEKEKTKAIEKNQQAIDQLNIAFEDGYRYFLSDKAKGKDN-----NKDEDPQSATNN 254 P++ +E+ KA+EK ++A +Q A +D ++AK + N N +PQ+ +NN Sbjct: 138 PKELEEQKKALEKEKEAKEQAQKAQKDKREKRKEERAKNRANLENLTNAMSNPQNLSNN 196
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 66.4 bits (162), Expect = 5e-14 Identities = 31/168 (18%), Positives = 65/168 (38%), Gaps = 9/168 (5%) Query: 2 AIKVLVVDDSSFFRRRVSEIVNQDPELEVIATASNGAEAVKMAAELNPQVITMDIEMPVM 61 +LV DD + R +++ +++ + SN A + A + ++ D+ MP Sbjct: 3 GATILVADDDAAIRTVLNQALSR--AGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 62 DGITAVREIMAKCP-TPILMFSSLTHDGAKATLDALDAGALDFLPKRFEDIATNKDDAIL 120 + + I P P+L+ S+ + + A + GA D+LPK F D+ Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSA--QNTFMTAIKASEKGAYDYLPKPF-DLTELIGIIGR 117 Query: 121 LLQQRVKALGRRRMFRPIARPVVASTPSVRPTSSVLGTTSIASHTPAT 168 L + + + P+V + +++ + + T T Sbjct: 118 ALAEPKRRPSKLEDDSQDGMPLVGRSAAMQ---EIYRVLARLMQTDLT 162
>PF06580#Sensor histidine kinase Length = 349 Score = 45.2 bits (107), Expect = 6e-07 Identities = 18/105 (17%), Positives = 37/105 (35%), Gaps = 23/105 (21%) Query: 430 TLNKEIDLIMV---------GEETDLDKNLVEALADPLVH------LVRNSVDHGIEMPN 474 +L E+ ++ + + + A+ D V LV N + HGI Sbjct: 217 SLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGIA--- 273 Query: 475 EREANGKPRTGTITLSASQEGDHILLKIEDDGAGMDPEKLKKIAI 519 P+ G I L +++ + L++E+ G+ + Sbjct: 274 -----QLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGT 313
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.9 bits (223), Expect = 3e-24 Identities = 33/105 (31%), Positives = 51/105 (48%), Gaps = 3/105 (2%) Query: 6 KILIVDDFSTMRRIIKNLLRDLGFNNTQEADDGSTALPMLQKGDFDFVVTDWNMPGMQGI 65 IL+ DD + +R ++ L G++ + +T + GD D VVTD MP Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 66 DLLKAIRADDSLKHLPVLMVTAEAKREQIIAAAQAGVNGYVVKPF 110 DLL I+ LPVL+++A+ I A++ G Y+ KPF Sbjct: 64 DLLPRIKKAR--PDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPF 106
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.8 bits (69), Expect = 0.013 Identities = 9/25 (36%), Positives = 12/25 (48%) Query: 240 VKQGGVVALVGPTGVGKTTSLAKLA 264 K V L G G+GK+T + L Sbjct: 593 CKFDYSVVLEGTGGIGKSTLINTLV 617
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 331 bits (851), Expect = e-114 Identities = 93/347 (26%), Positives = 179/347 (51%), Gaps = 2/347 (0%) Query: 6 SGERSEEPTGRRLEQAREKGQIARSKELGTAAVLISAACGFYMLGPSLATSLTRVFETVF 65 SGE++E+PT +++ AR+KGQ+A+SKE+ + A++++ + L +++ + Sbjct: 2 SGEKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLM--LI 59 Query: 66 TMDRAQIFDTEEMFNVWGVVASEIAWPMAKIMLLIVVVAFIGNVALGGMNFSTQAMMPKA 125 +++ + ++ + V V E + ++ + ++A +V G S +A+ P Sbjct: 60 PAEQSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDI 119 Query: 126 SKMSPAAGLKRMFGVQALVELTKGIAKFSVVAFSAYLLLSFYFNDIMLLSSDHLPGNVYH 185 K++P G KR+F +++LVE K I K +++ ++++ ++ L + + Sbjct: 120 KKINPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPL 179 Query: 186 ALDLLVWMFILLCSSILLIVVIDVPFQIWNHNKQLKMTKQEVKDEYKDTEGKPEVKGRVR 245 +L + ++ ++I + D F+ + + K+LKM+K E+K EYK+ EG PE+K + R Sbjct: 180 LGQILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKRR 239 Query: 246 QMQRELAQRRMMTEVPNADVIVVNPEHFAVAIKYDVQRSAAPFVIAKGVDDVAFKIREIA 305 Q +E+ R M V + V+V NP H A+ I Y + P V K D +R+IA Sbjct: 240 QFHQEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIA 299 Query: 306 REHNIAIVSAPPLARAIYHTTKLDQQIPEGLFTAVAQILAYVFQLRQ 352 E + I+ PLARA+Y +D IP A A++L ++ + Sbjct: 300 EEEGVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQNI 346
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 124 bits (313), Expect = 1e-36 Identities = 93/243 (38%), Positives = 143/243 (58%), Gaps = 1/243 (0%) Query: 15 YMWPLFRVASMLMVMVVFGAATTPSRVRLLLAMAITFAIAPVLPPVQNADLFSLSAVFIT 74 Y WPL RV +++ + + P RV+L LAM ITFAIAP LP + +FS A+++ Sbjct: 16 YFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLP-ANDVPVFSFFALWLA 74 Query: 75 AQQIIIGVAMGFVTQMVMQVFVLTGQIIGMQTSLGFASMVDPGSGQQTPVIGNFFLLLAT 134 QQI+IG+A+GF Q G+IIG+Q L FA+ VDP S PV+ +LA Sbjct: 75 VQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHLNMPVLARIMDMLAL 134 Query: 135 LIFLAVDGHLLMIRMLVASFETLPISNQGLTLTSYRALADWGSYMFGAALTMSISAIIAL 194 L+FL +GHL +I +LV +F TLPI + L ++ AL GS +F L +++ I L Sbjct: 135 LLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLIFLNGLMLALPLITLL 194 Query: 195 LLVNLSFGVMTRAAPQLNIFSIGFPITMIGGLFILWLTLTPVMEHFDEVWAAAQVLLCDM 254 L +NL+ G++ R APQL+IF IGFP+T+ G+ ++ + + + +++ LL D+ Sbjct: 195 LTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFCEHLFSEIFNLLADI 254 Query: 255 LAL 257 ++ Sbjct: 255 ISE 257
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 48.2 bits (115), Expect = 3e-11 Identities = 21/78 (26%), Positives = 40/78 (51%) Query: 4 EALIDIFREALAVIVMMVSAIVLPGLGIGLIVAVFQAATSINEQTLSFLPRLLVTLFGLM 63 + L+ +AL +++++ + IGL+V +FQ T + EQTL F +LL L Sbjct: 2 DDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLF 61 Query: 64 FMGHWLVETLMDFFVEMV 81 + W E L+ + +++ Sbjct: 62 LLSGWYGEVLLSYGRQVI 79
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 278 bits (712), Expect = 4e-97 Identities = 126/244 (51%), Positives = 184/244 (75%), Gaps = 3/244 (1%) Query: 4 RMLALVGLVILLCMPSAWAADGVLPAVTVTTGPDGSTEYSVTMQILLLMTSLSFLPAMLI 63 R+L++ +++ L P A+A LP +T P G +S+ +Q L+ +TSL+F+PA+L+ Sbjct: 3 RLLSVAPVLLWLITPLAFAQ---LPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILL 59 Query: 64 MLTSFTRIIIVLSILRQAIGLQQTPSNQVLIGMSLFMTFFIMAPVFDRIYDEGVKPYIEE 123 M+TSFTRIIIV +LR A+G P NQVL+G++LF+TFFIM+PV D+IY + +P+ EE Sbjct: 60 MMTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEE 119 Query: 124 QLTLQQAFEKGKEPLKGFMLGQVRTTDLKTFIEISGYKNIKSPEEAPMSVLIPAFITSEL 183 ++++Q+A EKG +PL+ FML Q R DL F ++ ++ PE PM +L+PA++TSEL Sbjct: 120 KISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSEL 179 Query: 184 KTAFQIGFMLFVPFLVLDLVVASILMAMGMMMLSPMIVSLPFKIMLFVLVDGWSLVLGTL 243 KTAFQIGF +F+PFL++DLV+AS+LMA+GMMM+ P ++LPFK+MLFVLVDGW L++G+L Sbjct: 180 KTAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSL 239 Query: 244 ANSF 247 A SF Sbjct: 240 AQSF 243
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 109 bits (274), Expect = 4e-34 Identities = 53/119 (44%), Positives = 79/119 (66%) Query: 7 DDWAAAMAEQALEEANAIELDELVDDSRPITKAEAAKLDTILDIPVTISMEVGRSYISIR 66 D WA A+ EQ + +D I+DIPV +++E+GR+ ++I+ Sbjct: 17 DLWADALNEQKATTTKSAADAVFQQLGGGDVSGAMQDIDLIMDIPVKLTVELGRTRMTIK 76 Query: 67 NLLQLNQGSVVELDRVAGEPLDVMVNGTLIAHGEVVVVNDKFGIRLTDVISQTERIKKL 125 LL+L QGSVV LD +AGEPLD+++NG LIA GEVVVV DK+G+R+TD+I+ +ER+++L Sbjct: 77 ELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGVRITDIITPSERMRRL 135
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 251 bits (642), Expect = 1e-83 Identities = 87/326 (26%), Positives = 163/326 (50%), Gaps = 11/326 (3%) Query: 1 MSDLLSQDEIDALLHGVDDVDDDDVDAVGE----DARSYDFSSQDRIVRGRMPTLEIVNE 56 M+++LSQDEID LL + D DA YDF D+ + +M TL +++E Sbjct: 1 MTEVLSQDEIDQLLTAISSGDASIEDARPISDTRKITLYDFRRPDKFSKEQMRTLSLMHE 60 Query: 57 RFARHLRISMFNMMRRAAEVSINGVQMLKFGEYVHTLFVPTSLNMVRFSPLKGTALITME 116 FAR S+ +R V + V L + E++ ++ P++L ++ PLKG A++ ++ Sbjct: 61 TFARLTTTSLSAQLRSMVHVHVASVDQLTYEEFIRSIPTPSTLAVITMDPLKGNAVLEVD 120 Query: 117 ARLVFILVDNFFGGDGRFHAKIEGREFTPTERRIVQLLLKIIFEDYKDAWAPVMDVEFDY 176 + F ++D FGG G+ R+ T E +++ ++ I + +++W V+D+ Sbjct: 121 PSITFSIIDRLFGGTGQAAKVQ--RDLTDIENSVMEGVIVRILANVRESWTQVIDLRPRL 178 Query: 177 LDSEVNPAMANIVSPTEVVVINSFHIEVDGGGGDFHITMPYSMIEPIRELLDAG--VQSD 234 E NP A IV P+E+VV+ + +V G + +PY IEPI L + S Sbjct: 179 GQIETNPQFAQIVPPSEMVVLVTLETKVGEEEGMMNFCIPYITIEPIISKLSSQFWFSSV 238 Query: 235 KQDTDMRWSQALHDEIMDVKVGFDANIVEHELTLKDVMNFKAGDIIPIE---LPEYIMMK 291 ++ + ++ L D++ V + A + L+++D++ + GDII + + + ++ Sbjct: 239 RRSSTTQYMGVLRDKLSTVDMDVVAEVGSLRLSVRDILGLRVGDIIRLHDTHVGDPFVLS 298 Query: 292 IEDLPTYRCKMGRSRDNLALKIHEKI 317 I + + C+ G +A +I E+I Sbjct: 299 IGNRKKFLCQPGVVGKKIAAQILERI 324
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 50.2 bits (119), Expect = 1e-08 Identities = 35/132 (26%), Positives = 63/132 (47%), Gaps = 5/132 (3%) Query: 592 MKQQLITMVSQGIQHAEIRLDPPELGHMLVKIQVHGDQTQVQFHVTQTQTRDLVEQAMPR 651 + Q + QG Q AE+RL P +LG + + ++V +Q Q+Q R +E A+P Sbjct: 244 LSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMVSPHQHVRAALEAALPV 303 Query: 652 LRELLQEQGMQLADSHVSQGGQGERREGGFGDGGGSNGTDVDEISAEE-----LHLGLNQ 706 LR L E G+QL S++S +++ + + ++ E+ + + L Sbjct: 304 LRTQLAESGIQLGQSNISGESFSGQQQAASQQQQSQRTANHEPLAGEDDDTLPVPVSLQG 363 Query: 707 ATSVNSGIDYYA 718 + NSG+D +A Sbjct: 364 RVTGNSGVDIFA 375
>FLGFLIJ#Flagellar FliJ protein signature. Length = 147 Score = 44.0 bits (103), Expect = 2e-08 Identities = 39/145 (26%), Positives = 70/145 (48%) Query: 1 MANADPLLLVLKLANDAEEQAALLLKSAQLECQKRLNQLSALNNYRLEYMKQMQSQQGQA 60 MA L + LA E AA LL + CQ+ QL L +Y+ EY + S Sbjct: 1 MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAG 60 Query: 61 ISASHYHQFHRFIRQIDDAITQQNRVVADGEKQKEYRQQHWLEKQKKRKAVELLLASKEK 120 I+++ + + +FI+ ++ AITQ + + ++ + W EK+++ +A + L + Sbjct: 61 ITSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQST 120 Query: 121 KRQVVEQKREQKMTDEFASQQFYRR 145 + E + +QK DEFA + R+ Sbjct: 121 AALLAENRLDQKKMDEFAQRAAMRK 145
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 89.1 bits (220), Expect = 6e-23 Identities = 57/201 (28%), Positives = 102/201 (50%), Gaps = 4/201 (1%) Query: 50 AAKPTTVESVSPPTMAEIEDIRAQAEEEGFA---EGKQQGYEQGLEKGRLEGLEQGHTEG 106 A + P IE+ E++ + +QGY+ G+ +GR +G +QG+ EG Sbjct: 16 APPQAEFVPIVEPEETIIEEAEPSLEQQLAQLQMQAHEQGYQAGIAEGRQQGHKQGYQEG 75 Query: 107 LAQGHEQGLETGLAQAKVLLSRFEALLTQFEKPLQLLDGDIELSLLNLSMTLAKSVIGHE 166 LAQG EQGL +Q + +R + L+++F+ L LD I L+ +++ A+ VIG Sbjct: 76 LAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRLMQMALEAARQVIGQT 135 Query: 167 LKTHPEQVLSALRLGIESLPIKEQAVTIRLHPDDVILVEQLYSTAQLTRSKWELEVDPTL 226 ++ ++ ++ P+ +R+HPDD+ V+ + A L+ W L DPTL Sbjct: 136 PTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLG-ATLSLHGWRLRGDPTL 194 Query: 227 SAGDCILSSHRSLVDLTLSSR 247 G C +S+ +D ++++R Sbjct: 195 HPGGCKVSADEGDLDASVATR 215
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 287 bits (735), Expect = 1e-97 Identities = 109/350 (31%), Positives = 195/350 (55%), Gaps = 7/350 (2%) Query: 1 MAENKTKEVAPAAPPAFNIKDISGVEKTAILLLSLSEADAASILKHLEPKQVQKVGMAMA 60 M E K KE+ ++ ++G +K AILL+S+ ++ + K+L ++++ + +A Sbjct: 1 MEEKKEKEIL-------DVSALTGKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIA 53 Query: 61 AMDEFGQEKVIGVHKLFLDDIQKYSSIGFNSEEFVRKALTAALGEDKAGNLIEQIIMGSG 120 ++ E V F + + I ++ R+ L +LG KA ++I + Sbjct: 54 KLETITSELKDNVLLEFKELMMAQEFIQKGGIDYARELLEKSLGTQKAVDIINNLGSALQ 113 Query: 121 AKGLDSLKWMDARQVATIIQNEHPQIQTIVLSYLEPDQAAEIFGQFPENTRLDLMMRIAN 180 ++ + ++ D + IQ EHPQ ++LSYL+P +A+ I P + ++ RIA Sbjct: 114 SRPFEFVRRADPANILNFIQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIAL 173 Query: 181 LEEVQPAALQELNDIMEKQFAGQGGAQAAKMGGLKAAANIMNYLDTGIESQLMETMRESD 240 ++ P ++E+ ++EK+ A GG+ I+N D E ++E++ E D Sbjct: 174 MDRTSPEVVREVERVLEKKLASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEED 233 Query: 241 EEMAQQIQDLMFVFENLIDVDDRGIQALLREVQQDVLMKALKGTDDQLKEKILGNMSKRA 300 E+A++I+ MFVFE+++ +DDR IQ +LRE+ L KALK D ++EKI NMSKRA Sbjct: 234 PELAEEIKKKMFVFEDIVLLDDRSIQRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRA 293 Query: 301 AELLRDDLEAMGPIRISEVEVAQKEILSIARRLSDSGEIMLGGGGGDEFL 350 A +L++D+E +GP R +VE +Q++I+S+ R+L + GEI++ GG ++ L Sbjct: 294 ASMLKEDMEFLGPTRRKDVEESQQKIVSLIRKLEEQGEIVISRGGEEDVL 343
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 303 bits (778), Expect = 2e-98 Identities = 162/566 (28%), Positives = 261/566 (46%), Gaps = 54/566 (9%) Query: 25 NLGGVDMMRQVTMILALAICLALAVFVMLWAQEPEYRPL-GKMETQEMVQVLDVLDKNKV 83 L + ++ +I+A + +A+ V ++LWA+ P+YR L + Q+ ++ L + + Sbjct: 15 WLNRLRANPRIPLIVAGSAAVAIVVAMVLWAKTPDYRTLFSNLSDQDGGAIVAQLTQMNI 74 Query: 84 KYQIDVD--VIKVPEDKYQEVKMMLSRAGVDSPAASQDFLNQDSGFGVSQRMEQARLKHS 141 Y+ I+VP DK E+++ L++ G+ A L FG+SQ EQ + + Sbjct: 75 PYRFANGSGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQFSEQVNYQRA 134 Query: 142 QEENLARAIEQLQSVSRAKVILALPKENVFARNASKPSATVVINTRRG-GLGQGEVDAIV 200 E LAR IE L V A+V LA+PK ++F R PSA+V + G L +G++ A+V Sbjct: 135 LEGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLEPGRALDEGQISAVV 194 Query: 201 DIVASAVQGLEPSRVTVTDSNGRLLNSGSQDGASATARRELELVQQKEAEYRTKIESILV 260 +V+SAV GL P VT+ D +G LL + G +L+ E+ + +IE+IL Sbjct: 195 HLVSSAVAGLPPGNVTLVDQSGHLLTQSNTSGRDL-NDAQLKFANDVESRIQRRIEAILS 253 Query: 261 PILGPDNFTSQVDVSMDFTAVEQTSKRYNPDLPSLRSEMTVENNTT-----GGSSGGIPG 315 PI+G N +QV +DF EQT + Y+P+ + ++ + G GG+PG Sbjct: 254 PIVGNGNVHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQVGAGYPGGVPG 313 Query: 316 ALSNQPP---------------MESNIPQDAT-KATESVTAGNSHREATRNFELDTTISH 359 ALSNQP N PQ +T + S ++ R T N+E+D TI H Sbjct: 314 ALSNQPAPPNEAPIATPPTNQQNAQNTPQTSTSTNSNSAGPRSTQRNETSNYEVDRTIRH 373 Query: 360 TRQQVGAVRRISVSVAVDFKPGAAGENGQVARVARTEQELTNIRRLLEGAVGFSSQRGDV 419 T+ VG + R+SV+V V++K A G+ + T ++ I L A+GFS +RGD Sbjct: 374 TKMNVGDIERLSVAVVVNYKTLADGKP-----LPLTADQMKQIEDLTREAMGFSDKRGDT 428 Query: 420 LEVVTVPFMDQLVEDLPALELWEQPWFWRAIKLGIGALVILV----LILAVVRPMLKRLI 475 L VV PF + L W+Q F + L++LV L VRP L R + Sbjct: 429 LNVVNSPF-SAVDNTGGELPFWQQQSFIDQLLAAGRWLLVLVVAWILWRKAVRPQLTRRV 487 Query: 476 --YPDSVSMPEDGRLGNELAEIEDQYAADTLGMLNTQEAEYSYADDGSIHIPNLHKDDDM 533 + + + E E+ Q + M Sbjct: 488 EEAKAAQEQAQVRQETEEAVEVRLSKDEQLQQRRANQRLGA----------------EVM 531 Query: 534 IKAIRALVANEPELSTQVVKNWLQDN 559 + IR + N+P + V++ W+ ++ Sbjct: 532 SQRIREMSDNDPRVVALVIRQWMSND 557
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 56.6 bits (136), Expect = 6e-14 Identities = 29/86 (33%), Positives = 45/86 (52%) Query: 26 QPNIMQQVNNTSGADFGQLLSQAVGNVSGLQSTSSNLATRLEMGDTTVTLSDTVIAREKA 85 Q+ F L A+ +S Q+ + A + +G+ V L+D + +KA Sbjct: 18 MSARAQESLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTLGEPGVALNDVMTDMQKA 77 Query: 86 SVAFEATVQVRNKLVEAYKEIMSMPV 111 SV+ + +QVRNKLV AY+E+MSM V Sbjct: 78 SVSMQMGIQVRNKLVAAYQEVMSMQV 103
>FLAGELLIN#Flagellin signature. Length = 507 Score = 141 bits (356), Expect = 8e-41 Identities = 99/270 (36%), Positives = 133/270 (49%), Gaps = 9/270 (3%) Query: 2 AITVNTNVTSMKAQKNLNASGNALATSMERLSSGLRINSAKDDAAGLAISNRLNSQVRGL 61 A +NTN S+ Q NLN S ++L++++ERLSSGLRINSAKDDAAG AI+NR S ++GL Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 DVGMRNANDGISVAQIAEGAMQEQTNMLQRMRDLSVQAVNGANSTSDKDAIQAEIDQLAL 121 RNANDGIS+AQ EGA+ E N LQR+R+LSVQA NG NS SD +IQ EI Q Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 EITAISNTTAFGDTKLLSGGFSAKSFQVGHQEGENISISISGTDAGTLSVDALLVSSDSA 181 EI +SN T F K+LS QVG +GE I+I + D +L +D V+ Sbjct: 121 EIDRVSNQTQFNGVKVLSQDNQ-MKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKE 179 Query: 182 AS--------TSIGLIDAAIKTIDTQRAKLGATQNRLAHNISNSANTQANVADAKSRIVD 233 A+ ++ D + R + + + A D Sbjct: 180 ATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTD 239 Query: 234 VDFAKETSQMTKNQVLQQTGSAMLAQANQL 263 + K + A A + Sbjct: 240 DAENNTAVDLFKTTKSTAGTAEAKAIAGAI 269 Score = 85.1 bits (210), Expect = 7e-21 Identities = 56/265 (21%), Positives = 98/265 (36%) Query: 7 TNVTSMKAQKNLNASGNALATSMERLSSGLRINSAKDDAAGLAISNRLNSQVRGLDVGMR 66 N T++ K ++ + D G+ + + G Sbjct: 242 ENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGNGKVST 301 Query: 67 NANDGISVAQIAEGAMQEQTNMLQRMRDLSVQAVNGANSTSDKDAIQAEIDQLALEITAI 126 N +A+ ++ + N D ++ A Sbjct: 302 TINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSDLEAN 361 Query: 127 SNTTAFGDTKLLSGGFSAKSFQVGHQEGENISISISGTDAGTLSVDALLVSSDSAASTSI 186 + + ++A + + ++ ++ + + + Sbjct: 362 NAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINEDAAAAKKSTANPL 421 Query: 187 GLIDAAIKTIDTQRAKLGATQNRLAHNISNSANTQANVADAKSRIVDVDFAKETSQMTKN 246 ID+A+ +D R+ LGA QNR I+N NT N+ A+SRI D D+A E S M+K Sbjct: 422 ASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYATEVSNMSKA 481 Query: 247 QVLQQTGSAMLAQANQLPQVALSLL 271 Q+LQQ G+++LAQANQ+PQ LSLL Sbjct: 482 QILQQAGTSVLAQANQVPQNVLSLL 506
>FLAGELLIN#Flagellin signature. Length = 507 Score = 143 bits (362), Expect = 1e-41 Identities = 96/270 (35%), Positives = 135/270 (50%), Gaps = 9/270 (3%) Query: 2 AITVNTNVTSMKAQKNLNTSGNALATSMERLSSGLRINSAKDDAAGLAISNRLNSQVRGL 61 A +NTN S+ Q NLN S ++L++++ERLSSGLRINSAKDDAAG AI+NR S ++GL Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 EVGMRNANDGISVAQVAEGAMQEQTNMLQRMRDLAVQSVNGANSTSDKEALQAEIDQLTS 121 RNANDGIS+AQ EGA+ E N LQR+R+L+VQ+ NG NS SD +++Q EI Q Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 EITAISNSTAFGDTKLLSGGFTGKSFQVGHQEGENISISISGTDATTLGVNALVVSSDTA 181 EI +SN T F K+LS QVG +GE I+I + D +LG++ V+ Sbjct: 121 EIDRVSNQTQFNGVKVLSQDNQ-MKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKE 179 Query: 182 AS--------TAIGAIDSALKLIDTQRATLGAVQNRLAHNISNSANTQSNVADAKSRIVD 233 A+ + D+ + R + + + A D Sbjct: 180 ATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTD 239 Query: 234 VDFAKETAQMTKNQVLQQTGSSMLAQANQL 263 + K + A A + Sbjct: 240 DAENNTAVDLFKTTKSTAGTAEAKAIAGAI 269 Score = 86.3 bits (213), Expect = 3e-21 Identities = 60/265 (22%), Positives = 102/265 (38%) Query: 7 TNVTSMKAQKNLNTSGNALATSMERLSSGLRINSAKDDAAGLAISNRLNSQVRGLEVGMR 66 N T++ K ++ + D G+ + + G Sbjct: 242 ENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGNGKVST 301 Query: 67 NANDGISVAQVAEGAMQEQTNMLQRMRDLAVQSVNGANSTSDKEALQAEIDQLTSEITAI 126 N VA+ ++ + N + S++ A Sbjct: 302 TINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSDLEAN 361 Query: 127 SNSTAFGDTKLLSGGFTGKSFQVGHQEGENISISISGTDATTLGVNALVVSSDTAASTAI 186 + + +T + + +N ++ + + + Sbjct: 362 NAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINEDAAAAKKSTANPL 421 Query: 187 GAIDSALKLIDTQRATLGAVQNRLAHNISNSANTQSNVADAKSRIVDVDFAKETAQMTKN 246 +IDSAL +D R++LGA+QNR I+N NT +N+ A+SRI D D+A E + M+K Sbjct: 422 ASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYATEVSNMSKA 481 Query: 247 QVLQQTGSSMLAQANQLPQVALSLL 271 Q+LQQ G+S+LAQANQ+PQ LSLL Sbjct: 482 QILQQAGTSVLAQANQVPQNVLSLL 506
>FLAGELLIN#Flagellin signature. Length = 507 Score = 57.4 bits (138), Expect = 5e-11 Identities = 41/242 (16%), Positives = 83/242 (34%), Gaps = 3/242 (1%) Query: 20 QTATSKILDQLSSGKKVNTAGDDPVASQGIDNLNQKNALVDQFMKNIDYATNRLAVTESK 79 Q++ S +++LSSG ++N+A DD + + Q +N + + TE Sbjct: 21 QSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQASRNANDGISIAQTTEGA 80 Query: 80 LGSAEDLTGSIREQVMRAINGTLSGTERQMIADEMKGSMEELLSIANSKDESGNYMFSGF 139 L + +RE ++A NGT S ++ + I DE++ +EE+ ++N +G + S Sbjct: 81 LNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEEIDRVSNQTQFNGVKVLSQ- 139 Query: 140 STDKEPFAFDNSTPPKIVYSGDSGVRNSLVQTGVAMGTNI--PGDSAFMKAPNGLGDYSV 197 + N + V++ + G GD D Sbjct: 140 DNQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKEATVGDLKSSFKNVTGYDTYA 199 Query: 198 NYLASQQGEFSVKTAKIADTATYVADTYTFNFTDNGAGGTNLQVLDSANNPVANVANFDA 257 + + + TA V D N + + + + + + Sbjct: 200 VGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTDDAENNTAVDLFKTTKSTAGT 259 Query: 258 TN 259 Sbjct: 260 AE 261
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 207 bits (529), Expect = 2e-61 Identities = 122/455 (26%), Positives = 192/455 (42%), Gaps = 19/455 (4%) Query: 4 DLLNIARTGVLASQSQLGVTSNNIANANTAGYHRQVATQSTLESQRLGNSFYGTGTYVND 63 L+N A +G+ A+Q+ L SNNI++ N AGY RQ + S + G G YV+ Sbjct: 2 SLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVSG 61 Query: 64 VKRIYNDYAARELRIGQTTLSAAEASYGKLSELDQLFSQIGKVVPQSLNNLFSGLNSIAD 123 V+R Y+ + +LR QT S A Y ++S++D + S + + + F+ L ++ Sbjct: 62 VQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLVS 121 Query: 124 LPADLGIRSSTLTNAQQVASSLNQMQSYLNGQLDQTNDQITGMTKRINEIGTELAKLNLE 183 D R + + ++ + + YL Q Q N I +IN ++A LN + Sbjct: 122 NAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLNDQ 181 Query: 184 LMKSPNQDA-----QLLDKQDALVQELSQYAQVNVIPQENGAKSIMLGGSVMLVSGEIAM 238 + + A LLD++D LV EL+Q V V Q+ G +I + LV G A Sbjct: 182 ISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTAR 241 Query: 239 SMGTQAGNPFPKELQLNSSISSQSVTVDPSKL--GGQLGAMFDYRDQTLIPAGHELDQLA 296 + + P + + P KL G LG + +R Q L + L QLA Sbjct: 242 QLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQLA 301 Query: 297 LGVADNFNKMQAQGIDLNGQVGANIFKDINDPMMSLGRAAGFSGNTGNATLGVTIDDTSL 356 L A+ FN G D NG G + F + + N G+ +G T+ D S Sbjct: 302 LAFAEAFNTQHKAGFDANGDAGEDFFA------IGKPAVLQNTKNKGDVAIGATVTDASA 355 Query: 357 LTGGAYELSF--TSPATYELRDTETGTITPLTLTGSILSGGSGFSIDIKAGAMASGDRFA 414 + Y++SF L T T+TP G G A D F Sbjct: 356 VLATDYKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFT----GTPAVNDSFT 411 Query: 415 IRPTAGASNGIEVVMKDPKGIAAASPKITADAANS 449 ++P + A ++V++ D IA AS + D+ N Sbjct: 412 LKPVSDAIVNMDVLITDEAKIAMASEEDAGDSDNR 446 Score = 87.7 bits (217), Expect = 3e-20 Identities = 38/104 (36%), Positives = 56/104 (53%) Query: 535 AEGDNSNAVAMAKLSESKVMNNGKSTLADVFENTKLDIGSKTKAAEVRTGSAEAVYQQAY 594 + DN N A+ L + G + D + + DIG+KT + + + V Q Sbjct: 441 GDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGNKTATLKTSSATQGNVVTQLS 500 Query: 595 ARVESESGVNLDEEAANLMRFQQAYQASARIMTTAQQIFDTLLS 638 + +S SGVNLDEE NL RFQQ Y A+A+++ TA IFD L++ Sbjct: 501 NQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALIN 544
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 152 bits (386), Expect = 1e-45 Identities = 66/151 (43%), Positives = 94/151 (62%), Gaps = 1/151 (0%) Query: 219 GSREEFLATLYPHAEKAAKALGTQPEVLLAQSALETGWGQKIVRGNNGAPSHNLFNIKAD 278 G + FLA L A+ A++ G ++LAQ+ALE+GWGQ+ +R NG PS+NLF +KA Sbjct: 147 GDSKAFLAQLSLPAQLASQQSGVPHHLILAQAALESGWGQRQIRRENGEPSYNLFGVKAS 206 Query: 279 RRWQGDKANVSTLEFEHGVAVQQKADFRVYSDFEHSFNDFVSFIAEGDRYQDAKKVAASP 338 W+G ++T E+E+G A + KA FRVYS + + +D+V + RY A AAS Sbjct: 207 GNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYLEALSDYVGLLTRNPRYA-AVTTAASA 265 Query: 339 TQFIRALQDAGYATDPRYAEKVIKVMQSISE 369 Q +ALQDAGYATDP YA K+ ++Q + Sbjct: 266 EQGAQALQDAGYATDPHYARKLTNMIQQMKS 296 Score = 87.8 bits (217), Expect = 1e-21 Identities = 39/91 (42%), Positives = 61/91 (67%), Gaps = 3/91 (3%) Query: 12 DLGGLDSLRAQAQKDEKGALKKVAQQFEGIFVQMLMKSMRDANAVFQSDSPLNSQYTKFY 71 D L+ L+A+A +D ++ VA+Q EG+FVQM++KSMRDA D +S++T+ Y Sbjct: 14 DAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALP---KDGLFSSEHTRLY 70 Query: 72 EQMRDQQLSVDLSDKGVLGLADMMVQQLSPE 102 M DQQ++ ++ LGLA+MMV+Q++PE Sbjct: 71 TSMYDQQIAQQMTAGKGLGLAEMMVKQMTPE 101
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 369 bits (949), Expect = e-129 Identities = 158/367 (43%), Positives = 222/367 (60%), Gaps = 14/367 (3%) Query: 5 LVLAVAVLVFSLPSQAE--RIKDIANVQGVRSNQLIGYGLVVGLPGTGEKTS---YTEQT 59 LV + + + P+QA+ RIKDIA++Q R NQLIGYGLVVGL GTG+ +TEQ+ Sbjct: 11 LVFSALPFLSTPPAQADTSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFTEQS 70 Query: 60 FMTMLKNFGINLPDNVKPKIKNVAVVAVHADMPAFIKPGQDLDVTVSSLGEAKSLRGGTL 119 ML+N GI + KN+A V V A++P F PG +DVTVSSLG+A SLRGG L Sbjct: 71 MRAMLQNLGITTQGG-QSNAKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRGGNL 129 Query: 120 LQTFLKGVDGNVYAIAQGSLVVSGFSADGLDGSKVIQNTPTVGRIPNGAIVERSVATPFS 179 + T L G DG +YA+AQG+L+V+GFSA G D + + Q T R+PNGAI+ER + + F Sbjct: 130 IMTSLSGADGQIYAVAQGALIVNGFSAQG-DAATLTQGVTTSARVPNGAIIERELPSKFK 188 Query: 180 TGDYLTFNLRRSDFSTAQRMADAINEL----LGPDMARPLDATSVQVSAPRDVSQRVSFL 235 L LR DFSTA R+AD +N G +A P D+ + V PR V+ + Sbjct: 189 DSVNLVLQLRNPDFSTAVRVADVVNAFARARYGDPIAEPRDSQEIAVQKPR-VADLTRLM 247 Query: 236 ATLENLDVIPAEESAKVIVNSRTGTIVVGQNVRLLPAAITHGGMTVTIAEATQVSQPNAL 295 A +ENL + + AKV++N RTGTIV+G +VR+ A+++G +TV + E+ QV QP Sbjct: 248 AEIENL-TVETDTPAKVVINERTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQPAPF 306 Query: 296 ANGQTTVTSNSTITATESDRRMFMFNPGTTLDELVRAVNLVGAAPSDVLAILEALKVAGA 355 + GQT V + I A + ++ + G L LV +N +G ++AIL+ +K AGA Sbjct: 307 SRGQTAVQPQTDIMAMQEGSKVAIVE-GPDLRTLVAGLNSIGLKADGIIAILQGIKSAGA 365 Query: 356 LHGELII 362 L EL++ Sbjct: 366 LQAELVL 372
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 143 bits (362), Expect = 1e-44 Identities = 74/227 (32%), Positives = 113/227 (49%), Gaps = 18/227 (7%) Query: 4 YLVLAVALL-LAACSSTQKKPLADDPFYAPVYPEAPPTKIAATGSIYQDSQ-----ASSL 57 Y + ++ +L L C+ PL A P P A GSI+Q +Q L Sbjct: 9 YAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTP---VANGSIFQSAQPINYGYQPL 65 Query: 58 YSDIRAHKVGDIITIVLKESTQAKKSAGNQIKKGSDMSLDPIFAGGSNVSI-----GGVP 112 + D R +GD +TIVL+E+ A KS+ + + F + G Sbjct: 66 FEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTN----FGFDTVPRYLQGLFGNAR 121 Query: 113 IDLRYKDSMNTKRESDADQSNSLDGSISANVMQVLNNGSLVIRGEKWISINNGDEFIRVT 172 D+ + A+ SN+ G+++ V QVL NG+L + GEK I+IN G EFIR + Sbjct: 122 ADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRFS 181 Query: 173 GLVRSQDIKPDNTIDSTRMANARIQYSGTGTFADAQKVGWLSQFFMS 219 G+V + I NT+ ST++A+ARI+Y G G +AQ +GWL +FF++ Sbjct: 182 GVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLN 228
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 43.0 bits (101), Expect = 7e-07 Identities = 18/119 (15%), Positives = 40/119 (33%), Gaps = 4/119 (3%) Query: 145 DNATSITVSAEGEVSVKTPGTAENQVVGQLTMTDFINPSGLDPMGQNLYTETG---ASGT 201 + I +++E + + + Q + +L ++ G A+ Sbjct: 427 TDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGNKTATLK 486 Query: 202 PIQGTASLDGMGAIRQGALETSNVNVTEELVNLIESQRIYEMNSKVISAVDQMLSYVTQ 260 T + + S VN+ EE NL Q+ Y N++V+ + + + Sbjct: 487 TSSATQGNV-VTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALIN 544 Score = 35.7 bits (82), Expect = 2e-04 Identities = 9/36 (25%), Positives = 20/36 (55%) Query: 5 LWISKTGLDAQQTDIAVISNNVANASTVGYKKSRAV 40 + + +GL+A Q + SNN+++ + GY + + Sbjct: 4 INNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTI 39
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 134 bits (338), Expect = 4e-42 Identities = 64/132 (48%), Positives = 84/132 (63%), Gaps = 2/132 (1%) Query: 25 KAAQENIRLGNEFLTQNKTKEGVITTASGLQYQVLTKGDGTVHPKASDTVTVHYHGTLID 84 K A+EN G+ FL+ NK+K G++ SGLQY+++ G G P SDTVTV Y GTLID Sbjct: 99 KKAEENKAKGDAFLSANKSKPGIVVLPSGLQYKIIDAGTGA-KPGKSDTVTVEYTGTLID 157 Query: 85 GTVFDSSVDRGEPIAFPLNRVIKGWTEGVQLMVVGDKVRFFIPSVLAYGNSST-GKIGGG 143 GTVFDS+ G+P F +++VI GWTE +QLM G F+P+ LAYG S G IG Sbjct: 158 GTVFDSTEKAGKPATFQVSQVIPGWTEALQLMPAGSTWEVFVPADLAYGPRSVGGPIGPN 217 Query: 144 SVLIFDVELLKI 155 LIF + L+ + Sbjct: 218 ETLIFKIHLISV 229
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 47.8 bits (113), Expect = 2e-07 Identities = 35/168 (20%), Positives = 62/168 (36%), Gaps = 11/168 (6%) Query: 542 WEIDADNGDILNAMHEGLGHGEGTTPPVNKAPIANAGADVNVTGPTDVVLNGSGSRDPEN 601 ++D + + + + G+ T VNK P A +D +V ++ +G+ S+D + Sbjct: 744 HKVDGNGNYVYDVVFHGMNTDTNTDVHVNKEPKAVIKSDSSVIVEEEINFDGTESKDEDG 803 Query: 602 EALTYLWTQVSGPTIAITNADMANAAIQLAATQTDVAYSFSLKVTDPEGLSATDSVTVTN 661 E Y W G ++ A A + T Y L VTD G T+S + Sbjct: 804 EIKAYEWDFGDGEK-----SNEAKATHKYNKTGE---YEVKLTVTDNNGGINTESKKIKV 855 Query: 662 KADTPNQAPVVSVAAT---ATVEAGKTVSIVASASDADGDALTYAWTV 706 D P + S + K+ +V + + Y + V Sbjct: 856 VEDKPVEVINESEPNNDFEKANQIAKSNMLVKGTLSEEDYSDKYYFDV 903
>FLAGELLIN#Flagellin signature. Length = 507 Score = 30.4 bits (68), Expect = 0.021 Identities = 14/87 (16%), Positives = 35/87 (40%), Gaps = 4/87 (4%) Query: 293 QLSGAMEEMSSTITEVAQNTHLTSTSINTAYDLCLKSSANMKANTQKVEQLAKSVADAAN 352 ++ +T+ ++N + + T + + N Q+V +L+ + N Sbjct: 48 AIANRFTSNIKGLTQASRNANDGISIAQTTE----GALNEINNNLQRVRELSVQATNGTN 103 Query: 353 NAHQLNKEAEQVANAMGEIDSIAEQTN 379 + L +++ + EID ++ QT Sbjct: 104 SDSDLKSIQDEIQQRLEEIDRVSNQTQ 130
>SECA#SecA protein signature. Length = 901 Score = 32.9 bits (75), Expect = 0.003 Identities = 37/175 (21%), Positives = 65/175 (37%), Gaps = 46/175 (26%) Query: 220 SQVVYPVEQRRKRELLSELIGK-KNWQQVLVFTATRDAADTLVKELNLDGIPSEVVHGDK 278 +VY E + + ++ ++ + Q VLV T + + ++ + EL GI V++ Sbjct: 424 PDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNA-- 481 Query: 279 GQGSRRRALREFVAGDVR---VLVATEVAARGLDI---------------PSLEYVVNYD 320 + A VA V +AT +A RG DI P+ E + Sbjct: 482 -KFHANEA--AIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIK 538 Query: 321 LPFLAED---------YV-----H---RI-----GRTGRAGKTGVAISFVSREEE 353 + ++ H RI GR+GR G G + ++S E+ Sbjct: 539 ADWQVRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDA 593
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.5 bits (157), Expect = 9e-13 Identities = 28/124 (22%), Positives = 48/124 (38%), Gaps = 2/124 (1%) Query: 678 QSLTVLAVDDNFANLKLIDTLLSELVTTVIAVNSGDEAVKQAKTRTFDLIFMDIQMPGTD 737 T+L DD+ A +++ LS V ++ + DL+ D+ MP + Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 738 GISATKQIRQGSMNRNTPIIAVTAHAIAEERELILGSGMDGYLPKPIDEEALKDVIHRWI 797 +I+ + P++ ++A G YLPKP D L +I R + Sbjct: 62 AFDLLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119 Query: 798 TRPK 801 PK Sbjct: 120 AEPK 123
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 28.2 bits (62), Expect = 0.024 Identities = 17/41 (41%), Positives = 25/41 (60%) Query: 142 EALDDFVFAHEVMEEEKELQNSLLEIIEENPKITAELVKGL 182 EAL DF+ A M++ ++ +EI EN K+TAEL K + Sbjct: 533 EALADFMLARFAMDQIQQWLKQSVEIFGENQKVTAELQKAM 573
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 37.0 bits (85), Expect = 2e-04 Identities = 55/328 (16%), Positives = 105/328 (32%), Gaps = 28/328 (8%) Query: 59 ANKTEVSAR--FSLDDIPLAKRWLEDNDLELDDECILRRTIGSDGRSRAYINGNPVPLTQ 116 T + L K + E+++ + + ++A + Sbjct: 34 VVNTNEVSAVATRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKD-------H 86 Query: 117 LKLLGQLLIGIHGQHAHHAMLKSEHQLTLLDSYANHRLLIDTVAASFQRCKQIEADLKQL 176 L + L + + SE + + A L + + A +K L Sbjct: 87 NDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTL 146 Query: 177 EASQHERIARKQLVQYQVEELDEFDLKVDEFDEIEQEHKRLANGTELIDTCQASLDILTE 236 EA + ARK ++ +E F + K L ++ QA L E Sbjct: 147 EAEKAALAARKADLEKALEGAMNFST------ADSAKIKTLEAEKAALEARQAEL----E 196 Query: 237 GEENNIESLLNRVVSLAEDLQSYDPALSNINTMLNDALIQVQESAGELQHYLSKLELDPT 296 + + + L++ AL+ L AL + + LE + Sbjct: 197 KALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAE-- 254 Query: 297 HFAYLEERLSKAMQLARKHHVSPNKLAEHHLALKAELSTLDSDESKLEEIQLQVDASRAA 356 A LE R ++ + + L+AE + L+++++ LE ++A+R Sbjct: 255 -KAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQ- 312 Query: 357 YLSNAQKLSQSRARYAK---ELDKLVTQ 381 S + L SR + E KL Q Sbjct: 313 --SLRRDLDASREAKKQLEAEHQKLEEQ 338 Score = 36.2 bits (83), Expect = 4e-04 Identities = 39/217 (17%), Positives = 71/217 (32%), Gaps = 14/217 (6%) Query: 167 KQIEADLKQLEASQHERIARKQLVQYQVEELD-EFDLKVDEFDEIEQEHKRLANGTELID 225 + A A K ++ + EL+ + ++ + K L + Sbjct: 165 EGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALA 224 Query: 226 TCQASLDILTEGEENNIESLLNRVVSLAEDLQSYDPALSNINTMLNDALIQVQESAGELQ 285 +A L+ EG N + ++ +L + + L L AL + Sbjct: 225 ARKADLEKALEGAMNFSTADSAKIKTLEAEKAA----LEARQAELEKALEGAMNFSTADS 280 Query: 286 HYLSKLELDPTHFAYLEERLSKAMQLARKHHVSPNKLAEHHLALKAELSTLDSDESKLEE 345 + LE A LE + ++ + + L A + L+++ KLEE Sbjct: 281 AKIKTLE---AEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEE 337 Query: 346 IQLQVDASRAAYLSNAQKLSQSRARYAK---ELDKLV 379 Q S A+ S + L SR + E KL Sbjct: 338 ---QNKISEASRQSLRRDLDASREAKKQLEAEHQKLE 371
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 27.4 bits (61), Expect = 0.025 Identities = 9/39 (23%), Positives = 16/39 (41%) Query: 76 LSDLAAMGAEPAWMTLALTLPEVDETWLSGFSEGLFEAA 114 + DL G + ++ L L+ + G GLF+ Sbjct: 1 MDDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTV 39
>SECGEXPORT#Protein-export SecG membrane protein signature. Length = 110 Score = 118 bits (297), Expect = 4e-38 Identities = 61/111 (54%), Positives = 81/111 (72%), Gaps = 1/111 (0%) Query: 1 MYEVLVVIYLLVALGLIGLVLIQQGKGADMGASFGAGASGTLFGSSGSGNFLTRTTAILA 60 MYE L+V++L+VA+GL+GL+++QQGKGADMGASFGAGAS TLFGSSGSGNF+TR TA+LA Sbjct: 1 MYEALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFGSSGSGNFMTRMTALLA 60 Query: 61 IAFFTLSLLIGNLSANHAKNEDSWNNLGSDTEQVTQPVEQGTQKSETKIPD 111 FF +SL++GN+++N W NL S + Q K + IP+ Sbjct: 61 TLFFIISLVLGNINSNKTNKGSEWENL-SAPAKTEQTQPAAPAKPTSDIPN 110
>adhesinb#Adhesin B signature. Length = 310 Score = 31.4 bits (71), Expect = 0.003 Identities = 18/95 (18%), Positives = 34/95 (35%), Gaps = 16/95 (16%) Query: 142 REARRTFEVIAEELDIVIQKNGTMAFDNAIIAY----EPLWAVGTGKSATPEQAQEVHAF 197 +EA+ F I E +++ G F AY +W + T + TP+Q + + Sbjct: 186 KEAKEKFNNIPGEKKMIVTSEG--CFKYFSKAYNVPSAYIWEINTEEEGTPDQIKTLVEK 243 Query: 198 IRKRLSEVSPFIGENIRILYGGSVTPSNAADLFAQ 232 +RK + L+ S ++ Sbjct: 244 LRKT----------KVPSLFVESSVDDRPMKTVSK 268
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 34.0 bits (78), Expect = 0.002 Identities = 23/82 (28%), Positives = 32/82 (39%), Gaps = 18/82 (21%) Query: 198 VLMVGPPGTGKTLLAKAIAGESK---VPFFT-----ISGSDFVEMFVGV------GASRV 243 +++ G GTGK L+A+A+ K PF I G GA Sbjct: 163 LMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTR 222 Query: 244 RD-MFEQAKKSAPCIIFIDEID 264 FEQA+ +F+DEI Sbjct: 223 STGRFEQAEGGT---LFLDEIG 241
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 246 bits (630), Expect = 1e-82 Identities = 91/306 (29%), Positives = 161/306 (52%), Gaps = 14/306 (4%) Query: 2 KNINLTKWRYVSSAISILLMITSLAIIGVKGFNWGLDFTGGVVTEVQLDRKITSSELQPL 61 N + +W++ + +I++MI S+ + V G N+G+DF GG + I + Sbjct: 12 TNFDFFRWQWATFGAAIVMMIASVILPLVIGLNFGIDFKGGTTIRTESTTAIDVGVYRAA 71 Query: 62 LNAAYQQEVSVILASEPG----------RWVLRYGDIKSADTEQSNVDIQ----QALAPL 107 L +V + +P R ++ + ++ AL + Sbjct: 72 LEPLELGDVIISEVRDPSFREDQHVAMIRIQMQEDGQGAEGQGAQGQELVNKVETALTAV 131 Query: 108 NSEVQVLNSSVVGPQIGQELAEQGGLALLVAMLCILGYLSYRFEWRLASGALFALVHDVV 167 + +++ + VGP++ EL +LL A + I+ Y+ RFEW+ A GA+ ALVHDV+ Sbjct: 132 DPALKITSFESVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGAVVALVHDVL 191 Query: 168 FVLAFFALTQMEFNLTVLAAVLAILGYSLNDSIIIADRIRELLIAKPKLAIQEINNQAIV 227 + FA+ Q++F+LT +AA+L I GYS+ND++++ DR+RE LI + ++++ N ++ Sbjct: 192 LTVGLFAVLQLKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRDVMNLSVN 251 Query: 228 ATFSRTMVTSGTTLMTVGALWIMGGGPLEGFSIAMFIGILTGTFSSISVGTSLPELLGLT 287 T SRT++T TTL+ + + I GG + GF AM G+ TGT+SS+ V ++ +GL Sbjct: 252 ETLSRTVMTGMTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAKNIVLFIGLD 311 Query: 288 PEHYKE 293 K+ Sbjct: 312 RNKEKK 317
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 78.0 bits (192), Expect = 1e-17 Identities = 30/172 (17%), Positives = 82/172 (47%), Gaps = 4/172 (2%) Query: 422 VTIVEERTIGPTLGAENIENGFAALGLGMGITLLFMALWYR-RLGWVANIALISNMVILF 480 + I ++GP + E + +L + + ++ + + + A +AL+ ++++ Sbjct: 135 LKITSFESVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGAVVALVHDVLLTV 194 Query: 481 GLLALIPGAVLTLPGIAGLVLTVGMAVDTNVLIFERIKDKLKEGRSFALA--IDTGFDSA 538 GL A++ L +A L+ G +++ V++F+R+++ L + ++ L ++ + Sbjct: 195 GLFAVL-QLKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRDVMNLSVNET 253 Query: 539 FSTIFDANFTTMITAVVLYSIGNGPIQGFALTLGLGLLTSMFTGIFASRALI 590 S TT++ V + G I+GF + G+ T ++ ++ ++ ++ Sbjct: 254 LSRTVMTGMTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAKNIV 305
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 32.2 bits (73), Expect = 0.001 Identities = 19/88 (21%), Positives = 36/88 (40%), Gaps = 16/88 (18%) Query: 109 IHQAVDASLARLQIDTIDLYQIHWPDRNTNFFG--ELFYDQQDQEHQTPILETLEALAEV 166 + +++ L+ + L++ HW + +FF E F +E ET++ +AE Sbjct: 13 VENSLNTQLSNWFLLYSKLHRFHWYVKGPHFFTLHEKF-----EELYDHAAETVDTIAER 67 Query: 167 IRQGKVRYIGVSNETPWGLMK-YLQLAE 193 + IG P +K Y + A Sbjct: 68 LLA-----IGGQ---PVATVKEYTEHAS 87
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 29.6 bits (66), Expect = 0.015 Identities = 28/115 (24%), Positives = 43/115 (37%), Gaps = 6/115 (5%) Query: 127 IHLGTGTLSTKFQ--HDVTNVYDGFQADITYYHPINLGFGDLVPYAGVHYFSKDFANYYT 184 I LG G +K Q H+ Q +T NLG + P GV Y A++ Sbjct: 1377 IDLGYGKFQSKLQTNHNAKFARHTAQFGLTAGKAFNLGNFGITPIVGVRYSYLSNADFAL 1436 Query: 185 G---VTSSEATAQRPAYQADGTFAYKLGYALVIP-LTKHLDITQATGYSRIAANM 235 + + + + Q D ++ Y LG V P L+ D Q +G + Sbjct: 1437 DQARIKVNPISVKTAFAQVDLSYTYHLGEFSVTPILSARYDANQGSGKINVNGYD 1491
>PF06580#Sensor histidine kinase Length = 349 Score = 29.1 bits (65), Expect = 0.031 Identities = 23/156 (14%), Positives = 46/156 (29%), Gaps = 36/156 (23%) Query: 258 RDLDTMEDLVMTLLSYARLDEANIQPDWQSIELNAWLLEKYQGQVYPDFSVELVSYPTAL 317 D +++ +L R S+ +++ Y + + + L Sbjct: 188 EDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSY-------LQLASIQFEDRL 240 Query: 318 K--IKTDPKYLSMQVNNLL-----NNALRFG------KAKIRLTLAVEEGATWLHVDDDG 364 + + +P + +QV +L N ++ G KI L + G L V++ G Sbjct: 241 QFENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTG 300 Query: 365 PGIDELESAQVIKPFVRGQHSRGNSGHGMGLAIVDR 400 + G GL V Sbjct: 301 SLALK----------------NTKESTGTGLQNVRE 320
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 75.6 bits (186), Expect = 6e-18 Identities = 37/126 (29%), Positives = 56/126 (44%), Gaps = 1/126 (0%) Query: 6 HILVVEDDISLAEWISDYLLDHGYEVTVASQGDFALEMIAEEIPDLVLLDVMLPVKNGFD 65 ILV +DD ++ ++ L GY+V + S IA DLV+ DV++P +N FD Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 66 VCKEARAFYAG-PILFMTACVEDGDEIRGLDVGADDYLTKPIRPQVLLARIKALLRRVGD 124 + + P+L M+A I+ + GA DYL KP L+ I L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 125 EEQKQQ 130 K + Sbjct: 125 RPSKLE 130
>OMS28PORIN#OMS28 porin signature. Length = 257 Score = 28.6 bits (63), Expect = 0.019 Identities = 14/44 (31%), Positives = 25/44 (56%), Gaps = 1/44 (2%) Query: 46 NRNQLRKSIRTARKSLSETEQIQASLSASQRMLDALQAQNAQHV 89 N++ K + ++ ++ EQ++ +L AS+R LD Q AQ V Sbjct: 166 NKSPNNKELELTKEEFAKVEQVKETLMASERALDE-TVQEAQKV 208
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 49.3 bits (117), Expect = 3e-09 Identities = 53/264 (20%), Positives = 97/264 (36%), Gaps = 36/264 (13%) Query: 5 IIITGVGKRIGYALAKHFLAQGQQVIG-----TYRSHYDSIDELNALGATLYPCDFYDDA 59 ITG + IG A+A+ +QG + S + A A +P D D A Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSA 70 Query: 60 QVQSLIDEL-TQLPQIRAIIHNASDWLPDPVLIKNEPLKSTTFTPSQVLQRMMQVHVSVP 118 + + + ++ I +++ A P + ++ TF+ V+ + Sbjct: 71 AIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFS----------VNSTGV 120 Query: 119 YQLNLALEAQLRAAAGDEIGGSDVIHITDYVAEKGSQKHIAYAASKAALHNMTLSFAAKF 178 + + ++ + D GS V + A AYA+SKAA T + Sbjct: 121 FNASRSVSKYMM----DRRSGSIVT-VGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLEL 175 Query: 179 APE-VKVNSIAPAMILFNM-----GDDAAYQQKTLAKAL-------LPKEAGNAEIIELV 225 A ++ N ++P +M D+ +Q L K A ++I + V Sbjct: 176 AEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAV 235 Query: 226 DYLL--NSRYVTGRCHNVDGGRQL 247 +L+ + ++T VDGG L Sbjct: 236 LFLVSGQAGHITMHNLCVDGGATL 259
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 145 bits (367), Expect = 1e-47 Identities = 43/150 (28%), Positives = 71/150 (47%), Gaps = 5/150 (3%) Query: 6 NQDDLVRIFKSILKEERFGSQSEIVTALQAEGFGNINQSKVSRMLSKFGAVRTRNAKQEM 65 N+ + I+ +Q E+V L+ +G+ N+ Q+ VSR + + V+ Sbjct: 2 NKGQRHIKIREIITANEIETQDELVDILKKDGY-NVTQATVSRDIKELHLVKVPTNNGSY 60 Query: 66 VYCLPAELGVPTAGSPLKNLV---LDVDHNQAMIVVRTSPGAAQLIARLLDSIGKPEGIL 122 Y LPA+ ++L+ + +D +IV++T PG AQ I L+D++ E I+ Sbjct: 61 KYSLPADQRFNPLSKLKRSLMDAFVKIDSASHLIVLKTMPGNAQAIGALMDNLDWEE-IM 119 Query: 123 GTIAGDDTIFICPSSIQDIADTLETIKSLF 152 GTI GDDTI I + D + I L Sbjct: 120 GTICGDDTILIICRTHDDTKVVQKKILELL 149
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 39.4 bits (92), Expect = 6e-06 Identities = 30/123 (24%), Positives = 47/123 (38%), Gaps = 23/123 (18%) Query: 1 MKIAILGATGWIGGAILKEALSRGHQVTAL-----VRDPS-------KLSATDVAVHAVD 48 MK + GA G+IG + K L GHQV + D S L+ H +D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 49 LE-QPLVAQTFA--GVDVVI-----AAVGGRAQQNHDLVASTV---QHLLDVLPNAKVPR 97 L + + FA + V AV + H S + ++L+ + K+ Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 98 LLW 100 LL+ Sbjct: 121 LLY 123
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 32.2 bits (73), Expect = 0.002 Identities = 22/118 (18%), Positives = 43/118 (36%), Gaps = 4/118 (3%) Query: 280 LTTLYNLALILGDQGRLDEWAEINKVLELARIRNPYYYYDMAQQAFDEHQYDEALAWYQR 339 L LY+LA G+ ++ ++ + L + + ++ + QYD A+ Y Sbjct: 36 LEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSY 95 Query: 340 A--LAKADYRHEFFFGLSKTYWALGDEKRAKLNMEKALALSRDDSERHRYQNKLQVML 395 + + R F G+ A+ + A L D +E ++ ML Sbjct: 96 GAIMDIKEPRFPFHAAEC--LLQKGELAEAESGLFLAQELIADKTEFKELSTRVSSML 151
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 43.1 bits (101), Expect = 2e-07 Identities = 39/190 (20%), Positives = 68/190 (35%), Gaps = 31/190 (16%) Query: 2 LKPEECVLVIVDVQGKLAQIMDNS----DKLHQQLQTLIQGAQLFEIPILWLEQLPDKLG 57 P VL+I D+Q +L ++ L IP+++ Q P G Sbjct: 26 PDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCVQLGIPVVYTAQ-P---G 81 Query: 58 ATSPELQTLLEK------TGSP-----------------IAKQHFSGWHCEEFAQALTKT 94 + +P+ + LL P + K +S + + + K Sbjct: 82 SQNPDDRALLTDFWGPGLNSGPYEEKIITELAPEDDDLVLTKWRYSAFKRTNLLEMMRKE 141 Query: 95 DRKHVILAGIETHVCVYQTCCDLIEQQYSVHLVADGVSSRSADNKQLGIQMMTARGALLT 154 R +I+ GI H+ T C+ + V D V+ S + Q+ ++ R A Sbjct: 142 GRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVADFSLEKHQMALEYAAGRCAFTV 201 Query: 155 NVESLLFELQ 164 +SLL +LQ Sbjct: 202 MTDSLLDQLQ 211
>PF06580#Sensor histidine kinase Length = 349 Score = 42.2 bits (99), Expect = 4e-06 Identities = 27/147 (18%), Positives = 55/147 (37%), Gaps = 17/147 (11%) Query: 415 INEGVSTAYVQLRELLSTFRLTIK-EPDLKSALEAMLEQLRAKTNI-------KITLDYK 466 I E + A L L R +++ + +L L + + + ++ + + Sbjct: 186 ILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQ 245 Query: 467 LAPQWLEAKQHIHILQITREATLNAIKHA-----EASLINIHCYKDDKGMVNIDVCDNGI 521 + P ++ + ++Q E N IKH + I + KD+ G V ++V + G Sbjct: 246 INPAIMDVQVPPMLVQTLVE---NGIKHGIAQLPQGGKILLKGTKDN-GTVTLEVENTGS 301 Query: 522 GIGHLKERDQHFGIGIMHERASKLSGK 548 + G+ + ER L G Sbjct: 302 LALKNTKESTGTGLQNVRERLQMLYGT 328
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 61.4 bits (149), Expect = 2e-13 Identities = 27/159 (16%), Positives = 61/159 (38%), Gaps = 9/159 (5%) Query: 6 SVLVVDDHPLLRKGICQLIASDPDFSLFGEAGGGLDALTAVATDEPDIILLDLNMKGMTG 65 ++LV DD +R + Q S + + +A + D+++ D+ M Sbjct: 5 TILVADDDAAIRTVLNQ-ALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 66 LDTLNAMRQEGVTSRIVILTVSDAKQDVIRLLRAGADGYLLKDTEPDLLLEKLKNAMLGH 125 D L +++ +++++ + I+ GA YL K + L+ + A+ Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL--- 119 Query: 126 RVISDEVEEYLYELKDATDEQEWISSLTPRELQILEQLA 164 E + +L+D + + + + +I LA Sbjct: 120 ----AEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLA 154
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 29.2 bits (65), Expect = 0.026 Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 5/86 (5%) Query: 10 GTSVADYNAMNRCADIVLANPHCRLVVVSASSGVTNLLVELTQESINDDGRLQRLK-QIA 68 +S A +C + LA + R +VS S T++ L + ++G Q +K + Sbjct: 158 ASSKAAAVMFTKCLGLELAEYNIRCNIVSPGSTETDMQWSLWAD---ENGAEQVIKGSLE 214 Query: 69 QIQYAI-LDKLGRPNDVAAALDKLLS 93 + I L KL +P+D+A A+ L+S Sbjct: 215 TFKTGIPLKKLAKPSDIADAVLFLVS 240
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 61.0 bits (148), Expect = 8e-13 Identities = 25/107 (23%), Positives = 44/107 (41%), Gaps = 3/107 (2%) Query: 146 RVLVVDDSRMARNVIKRTIGNLGMKLITEAEDGAQAIELMKNNMFDLVITDYNMPSVDGL 205 +LV DD R V+ + + G + + A + DLV+TD MP + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 206 ALTQYIRNESQQSHIPILMVSSEANDTHLSNVSQAGVNALCDKPFEP 252 L I+ + +P+L++S++ S+ G KPF+ Sbjct: 64 DLLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDL 108 Score = 47.1 bits (112), Expect = 3e-08 Identities = 34/155 (21%), Positives = 60/155 (38%), Gaps = 6/155 (3%) Query: 10 SILLVEPSDIQRRIIIQRLQQEGILSIQTAENIEAAKEIIARHKPDLIASAMHFDDGTAI 69 +IL+ + R ++ Q L + G ++ N IA DL+ + + D A Sbjct: 5 TILVADDDAAIRTVLNQALSRAG-YDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 70 DLLGYLRTSADCKDIQFMLVSSECRREQLEIFRQSGVVAILPKPFSADHLATALNATIDL 129 DLL ++ + D+ +++S++ + G LPKPF L + + Sbjct: 64 DLLPRIKKAR--PDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 130 LSHDELDLSNFDVQDVRVLVVDDSRM--ARNVIKR 162 L + D QD LV + M V+ R Sbjct: 122 PKRRPSKLED-DSQDGMPLVGRSAAMQEIYRVLAR 155
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 109 bits (275), Expect = 2e-35 Identities = 45/88 (51%), Positives = 66/88 (75%) Query: 2 NKTELIAKIAENADLTKVEAARALKSFEAAITESMKNGDKISIVGFGSFETATRAARTGR 61 NK +LIAK+AE +LTK ++A A+ + +A++ + G+K+ ++GFG+FE RAAR GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 62 NPQTGKEIQIAEATVPKFKAGKTLRDSV 89 NPQTG+EI+I + VP FKAGK L+D+V Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAV 90
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 60.6 bits (147), Expect = 7e-12 Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 3/102 (2%) Query: 3 LLLIDDDEVDRTAIIRALRQSKLTFNVIEANCAFDGLNLALERHFDGILLDYLLPDANGL 62 +L+ DDD RT + +AL S+ ++V + A D ++ D ++PD N Sbjct: 6 ILVADDDAAIRTVLNQAL--SRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 63 EVLIKLNAMTQDQTVVVMLSRYEDEKLAQRCIELGAQDFLLK 104 ++L ++ D V+VM S A + E GA D+L K Sbjct: 64 DLLPRIKKARPDLPVLVM-SAQNTFMTAIKASEKGAYDYLPK 104
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 48.3 bits (115), Expect = 1e-09 Identities = 24/112 (21%), Positives = 44/112 (39%), Gaps = 10/112 (8%) Query: 8 QQVTILLVDDDDVDYMAVQRAMRQLRLLNPLVRARDGIEALAILTSLDTIKGPYLILLDL 67 TIL+ DDD + +A+ + + + + + L++ D+ Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGY--DVRITSNAATLWRWIAA----GDGDLVVTDV 55 Query: 68 NMPRMNGFEFLERIRS-DPSLSSSVVFMLTTSSTDEDRMKAYSHHVAGYMVK 118 MP N F+ L RI+ P L V +++ +T +KA Y+ K Sbjct: 56 VMPDENAFDLLPRIKKARPDL---PVLVMSAQNTFMTAIKASEKGAYDYLPK 104
>PF06580#Sensor histidine kinase Length = 349 Score = 29.8 bits (67), Expect = 0.038 Identities = 20/107 (18%), Positives = 37/107 (34%), Gaps = 22/107 (20%) Query: 608 LVIRNLISNAIKH---HDLGTGVITVLCESTSKHYLFSVLDDGPGISSAYQNKVFEMFQT 664 ++++ L+ N IKH G I + + V + G Sbjct: 258 MLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGS---------------- 301 Query: 665 LKPRDEVEGSGLGLSLVKKTVESLGGN---IQLKSQGRGCCFYFTWP 708 L ++ E +G GL V++ ++ L G I+L + P Sbjct: 302 LALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 54.3 bits (130), Expect = 6e-11 Identities = 47/209 (22%), Positives = 78/209 (37%), Gaps = 25/209 (11%) Query: 30 PTIRTMTQAQAPTELNANTTAVLVIDFQNEYFTGSMP--IPNGKQALGKAKQVVKFAHQN 87 PT M Q + + N +L+ D Q YF + + +++ Q Sbjct: 12 PTASDMPQNKVSWVPDPNRAVLLIHDMQ-NYFVDAFTAGASPVTELSANIRKLKNQCVQL 70 Query: 88 AMPVYFVRHLGPAA-----------GPLFAEGSVNAEFHQDLQPLEIDFVINKATPSSFV 136 +PV + G GP G + +L P + D V+ K S+F Sbjct: 71 GIPVVYTAQPGSQNPDDRALLTDFWGPGLNSGPYEEKIITELAPEDDDLVLTKWRYSAFK 130 Query: 137 GTNLDQQLKEKGIKTLVITGLMTHMCVSSTARDAVPMGYDVIIAEDATATRDLATWDGSI 196 TNL + ++++G L+ITG+ H+ TA +A DA A D S+ Sbjct: 131 RTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVA-------DFSL 183 Query: 197 VDHATLQRAAIAGVADVFAEIKTTQAVLN 225 H + A+ A A T ++L+ Sbjct: 184 EKH----QMALEYAAGRCAFTVMTDSLLD 208
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 37.6 bits (87), Expect = 6e-06 Identities = 21/72 (29%), Positives = 31/72 (43%), Gaps = 5/72 (6%) Query: 75 ASIGRVVVSPAGRGKGLAMPLMQHAIESALTTWPDAGIQIGAQDY-LKA--FYQKLGFVA 131 A I + V+ R KG+ L+ AIE A G+ + QD + A FY K F+ Sbjct: 90 ALIEDIAVAKDYRKKGVGTALLHKAIEWAKEN-HFCGLMLETQDINISACHFYAKHHFII 148 Query: 132 CS-EMYLEDGIP 142 + + L P Sbjct: 149 GAVDTMLYSNFP 160
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 51.2 bits (122), Expect = 6e-10 Identities = 41/183 (22%), Positives = 80/183 (43%), Gaps = 5/183 (2%) Query: 2 ILITGASSGLGAALASLYAKENEPLTLTGRNAERLQTVANALTPFSNKPIAAITADLASE 61 ITGA+ G+G A+A A + + N E+L+ V ++L + A AD+ Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHA-EAFPADVRDS 69 Query: 62 SSLEALFDGL---TQAPKTVIHCAGSGYFGAIETQGASDIHSLLNNNVTSTILLVRELVK 118 ++++ + + +++ AG G I + + + + N T R + K Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSK 129 Query: 119 RYKDQ-AVTVVVVMSTAALAAKAGESTYCAAKWAVRGFIESVRLELKQSPMKLIAVYPGG 177 D+ + ++V V S A + + Y ++K A F + + LEL + ++ V PG Sbjct: 130 YMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGS 189 Query: 178 MDT 180 +T Sbjct: 190 TET 192
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 54.4 bits (131), Expect = 3e-10 Identities = 62/338 (18%), Positives = 113/338 (33%), Gaps = 23/338 (6%) Query: 40 MTLVPYIASDLGVD---VAHVSYAISAYALGVVVGSPIIMVLAVRVRRRTLLIALAALMA 96 M ++P + DL AH ++ YAL +P++ L+ R RR +L+ A A Sbjct: 25 MPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAA 84 Query: 97 VANGLSALAPSLNWLIFFRFLSGLPHGAYFGVAMLLAASLVPPEMKARAVSRVIIGLTLA 156 V + A AP L L R ++G+ GA VA A + + +AR + Sbjct: 85 VDYAIMATAPFLWVLYIGRIVAGIT-GATGAVAGAYIADITDGDERARHFGFMSACFGFG 143 Query: 157 TIIGVPFATWMGQTVGWRSGIGIVAILATITAVMVYFLAPDQAVAADASPRKELQ----- 211 + G MG + A L + + FL P+ + + P + Sbjct: 144 MVAGPVLGGLMGG-FSPHAPFFAAAALNGLNFLTGCFLLPE-SHKGERRPLRREALNPLA 201 Query: 212 ------TLKNREVWLTLGIAAIGFGGIFCVYTYLAETLIQVTQVEPFKIPIMMAVFGI-G 264 + + + G + + I I +A FGI Sbjct: 202 SFRWARGMTVVAALMAVFFIMQLVGQVPA--ALWVIFGEDRFHWDATTIGISLAAFGILH 259 Query: 265 ATLGTLVCGWAADK-SALAAAFWSLVLSTVVLAIYPSLTGHYWALMPV-VFFVGCGLGLA 322 + ++ G A + A ++ I + W P+ V G+G+ Sbjct: 260 SLAQAMITGPVAARLGERRALMLGMIADGTGY-ILLAFATRGWMAFPIMVLLASGGIGMP 318 Query: 323 TIVQARLMDVAPDGQAMTGALVQCAFNLANAIGPWVGS 360 + V + Q + +L + +GP + + Sbjct: 319 ALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFT 356
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 45.1 bits (107), Expect = 6e-07 Identities = 18/33 (54%), Positives = 22/33 (66%) Query: 499 IAAYTINPANALGISDITGSIVLGKSADFVVLE 531 IA YTINPA A G+S GS+ +GK AD V+ Sbjct: 406 IAKYTINPAIAHGLSHEIGSLEVGKRADLVLWN 438 Score = 38.6 bits (90), Expect = 6e-05 Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 8/75 (10%) Query: 27 NDELADTLLTNTHVYGHDQ--ATSLAIKDGKIVYIGNSIN--AMDHVS----NQTKVIDL 78 DT++TN + H + +KDG+I IG + N V+ T+VI Sbjct: 64 EGGAVDTVITNALILDHWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAG 123 Query: 79 KGHYLLPGFIDNHNH 93 +G + G +D+H H Sbjct: 124 EGKIVTAGGMDSHIH 138
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 86.1 bits (213), Expect = 3e-22 Identities = 33/118 (27%), Positives = 53/118 (44%), Gaps = 12/118 (10%) Query: 77 NILFPNDSAYIAPEYYPQIEEVAIFLRQY--PTTKVTIEGHTSRTGTDERNAVLSQDRAN 134 ++LF + A + PE ++++ L V + G+T R G+D N LS+ RA Sbjct: 220 DVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQ 279 Query: 135 AVTAVLAERFSIDRSRLTAIGYGSSRPVVLEQTPDAEIR---------NRRVVAEVTG 183 +V L + I +++A G G S PV + + R +RRV EV G Sbjct: 280 SVVDYLISK-GIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKG 336
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 28.1 bits (62), Expect = 0.025 Identities = 21/125 (16%), Positives = 46/125 (36%), Gaps = 8/125 (6%) Query: 36 QAATKGHEERAFNPQNERTADQTQQQTKTLENNQQQVQEKQQQQQSSQQQSQQQQEKKAP 95 + A + N Q A Q ++T E + +E ++ + + + ++ ++ P Sbjct: 1067 EVAKEAKSNVKANTQTNEVA---QSGSETKETQTTETKETATVEKEEKAKVETEKTQEVP 1123 Query: 96 LVVAERVLPKTLKIAARGQAALQRKD-----IRLKVSQGAANYASSNAKANTSSAARQSL 150 V ++ + + QA R++ I+ SQ + TSS Q + Sbjct: 1124 KVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPV 1183 Query: 151 QGEST 155 +T Sbjct: 1184 TESTT 1188
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 80.3 bits (198), Expect = 6e-19 Identities = 26/123 (21%), Positives = 50/123 (40%), Gaps = 3/123 (2%) Query: 14 KGKILIVDDQPLNIKILHQLFN-EEYELFMATNGEQAIAICQKVQPDLVLLDIEMPGMSG 72 IL+ DD +L+Q + Y++ + +N DLV+ D+ MP + Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 73 FDVCQHIKADPETATIGVIFVTAHFDEVQEVKGFQLGAVDFIHKPINPIITTARVKNQFT 132 FD+ IK + V+ ++A + +K + GA D++ KP + + Sbjct: 63 FDLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 133 LKR 135 + Sbjct: 121 EPK 123
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 72.6 bits (178), Expect = 6e-15 Identities = 33/135 (24%), Positives = 61/135 (45%), Gaps = 4/135 (2%) Query: 1287 TILVVEDNQLNRQVIDELLSYEGANVVLAEGGMEGVSLVLESGDLFDIVIMDMQMPDMDG 1346 TILV +D+ R V+++ LS G +V + + + D+V+ D+ MPD + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWI--AAGDGDLVVTDVVMPDENA 62 Query: 1347 LEATRRIRADERFAALPILAMTANASQSDRQECLNAGMNDHVGKPIDMPLLLPSILRLVG 1406 + RI+ + LP+L M+A + + G D++ KP D+ L+ I R + Sbjct: 63 FDLLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 1407 REDMTSAEFEGHWPE 1421 ++ E + Sbjct: 121 EPKRRPSKLEDDSQD 135 Score = 61.0 bits (148), Expect = 2e-11 Identities = 19/93 (20%), Positives = 38/93 (40%), Gaps = 8/93 (8%) Query: 1138 LSGYRVLVVDDNELTTEILEKILTGFGCEVETALGGYAALAKVKQSHEKSTPFDVVLMDW 1197 ++G +LV DD+ +L + L+ G +V + D+V+ D Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGD-----GDLVVTDV 55 Query: 1198 RMPDLDGLQTAEMLRNSDANNQTPLVVMLTAYG 1230 MPD + ++ + + P++VM +A Sbjct: 56 VMPDENAFDLLPRIKKARPD--LPVLVM-SAQN 85
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 98.0 bits (244), Expect = 9e-26 Identities = 38/129 (29%), Positives = 67/129 (51%) Query: 6 SKILVVDDDMRLRALLERYLMEQGYQVRSAANAEQMDRLLERENFHLLVLDLMLPGEDGL 65 + ILV DDD +R +L + L GY VR +NA + R + + L+V D+++P E+ Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 66 SICRRLRQQGNPIPIVMLTAKGDEVDRIIGLELGADDYLPKPFNPRELLARIKAVMRRQT 125 + R+++ +P+++++A+ + I E GA DYLPKPF+ EL+ I + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 126 QDVPGAPAQ 134 + Sbjct: 124 RRPSKLEDD 132
>PF06580#Sensor histidine kinase Length = 349 Score = 49.5 bits (118), Expect = 1e-08 Identities = 26/179 (14%), Positives = 56/179 (31%), Gaps = 28/179 (15%) Query: 261 IVNDIEDMDAIISQFIAYIRQDQETSRE----LGQINKLIQDVAQAEANRAGEIEVVLTD 316 I+ D +++ +R S L ++ Q + + + Sbjct: 186 ILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQ 245 Query: 317 CPEAQFQAIAIKRVLSNLVENAFRYG------SGWIRISSQFDGKRIGFTVEDNGPGIDE 370 A ++ LVEN ++G G I + D + VE+ G + Sbjct: 246 INPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALK 305 Query: 371 SQITKLFQPFTQGDIARGSVGSGLGLA-IIKRIIDRHQGQVTLS-NRAEGGLRAQVWLP 427 + +G GL + +R+ + + + + +G + A V +P Sbjct: 306 NTKE----------------STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 82.6 bits (204), Expect = 2e-20 Identities = 30/125 (24%), Positives = 61/125 (48%) Query: 2 RLLLVEDDLELQANLKQHLLDAHYSIDVASDGEEGLFQALEYNYDAAIIDVGLPKLDGIA 61 +L+ +DD ++ L Q L A Y + + S+ + D + DV +P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 LIRSVREQERDFPILILTARDSWQDKVEGLDAGADDYLTKPFHPQELVARLKALIRRSAG 121 L+ +++ D P+L+++A++++ ++ + GA DYL KPF EL+ + + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 KASPL 126 + S L Sbjct: 125 RPSKL 129
>PF06580#Sensor histidine kinase Length = 349 Score = 29.4 bits (66), Expect = 0.031 Identities = 15/80 (18%), Positives = 24/80 (30%), Gaps = 15/80 (18%) Query: 365 KAAKSTVKLTVTGDAYQLLICIEDDGPGISEALQNQIFERGIRADSYHQGNGIGLAIVRD 424 + L T D + + +E+ G + + G GL VR+ Sbjct: 275 LPQGGKILLKGTKDNGTVTLEVENTGSLA--------------LKNTKESTGTGLQNVRE 320 Query: 425 -LVDSYNGRISVSRSETLGG 443 L Y + SE G Sbjct: 321 RLQMLYGTEAQIKLSEKQGK 340
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 33.1 bits (75), Expect = 0.003 Identities = 23/153 (15%), Positives = 50/153 (32%), Gaps = 13/153 (8%) Query: 352 ERDNRAPSYQKTQAELKERRSATMVQTPTHKDRNDAQSRPVQSKPMPSKEPQQRQYQTRE 411 E K +++ E+ +T +++ + E Q +T+E Sbjct: 1035 ETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKE 1094 Query: 412 SQPRNVDQQRTPPQRQENPRTATPRVETPR----PEIRRAEPQRVEQPRQAAPRQREEVR 467 +Q + E A +VET + P++ + EQ P+ Sbjct: 1095 TQT----TETKETATVEKEEKA--KVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPA-- 1146 Query: 468 VRQSEPRQNAQTARSVEHNQGRSTQSQERRHRE 500 R+++P N + +S + + Q + Sbjct: 1147 -RENDPTVNIKEPQSQTNTTADTEQPAKETSSN 1178 Score = 32.7 bits (74), Expect = 0.004 Identities = 26/145 (17%), Positives = 46/145 (31%), Gaps = 18/145 (12%) Query: 361 QKTQAELKERRSATMVQTPTHKDRNDAQSRPVQSKPMP-------SKEPQQRQ-YQTRES 412 +K + E ++ + V + + +++ Q++P KEPQ + Sbjct: 1110 EKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTE 1169 Query: 413 QPRNVDQQRTPPQRQENPRTATPRVETPRPEIRRAEPQRVEQPRQAAPRQREEVRVRQSE 472 QP E+ T PE P P E + Sbjct: 1170 QPAKETSSNVEQPVTESTTVNTGNSVVENPE--------NTTPATTQPTVNSESSNKPKN 1221 Query: 473 PRQNAQTARSVEHNQGRSTQSQERR 497 ++ ++ RSV HN +T S R Sbjct: 1222 --RHRRSVRSVPHNVEPATTSSNDR 1244
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1244 bits (3221), Expect = 0.0 Identities = 655/1032 (63%), Positives = 807/1032 (78%), Gaps = 4/1032 (0%) Query: 1 MARFFIDRPIFAWVIALIIMLAGILSIRSLPVSQYPNIAPPTVVISANYPGASAKIVEDS 60 MA FFI RPIFAWV+A+I+M+AG L+I LPV+QYP IAPP V +SANYPGA A+ V+D+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQVIEQRMTGIDHLRYISSTSDSFGNASITLTFNAEADPDIAQVQVQNKLQGAMTLLPQ 120 VTQVIEQ M GID+L Y+SSTSDS G+ +ITLTF + DPDIAQVQVQNKLQ A LLPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVQSQGVNVNKSSSGFLMVLGFVSTDGSLDKGDIADYVGANIQDPMSRVPGVGEIQLFGA 180 EVQ QG++V KSSS +LMV GFVS + + DI+DYV +N++D +SR+ GVG++QLFGA Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QYAMRIWLDPLKLTQYNLTSLDVIAAIRSQNAQVSAGQLGGAPSVAGQELNATVSAQSRL 240 QYAMRIWLD L +Y LT +DVI ++ QN Q++AGQLGG P++ GQ+LNA++ AQ+R Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 QTAEEFRKIILKSDISGANVFLGDVARVELGSESYAVVSLYNGQPATGLAIKLATGANAL 300 + EEF K+ L+ + G+ V L DVARVELG E+Y V++ NG+PA GL IKLATGANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 DTASAVREKIAEMKPFFPQGLEVVYPYDTTPFVEQSIEGVVHTLLEAIVLVFVIMYLFLQ 360 DTA A++ K+AE++PFFPQG++V+YPYDTTPFV+ SI VV TL EAI+LVF++MYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NFRATLIPTIAVPVVLLGTFAILSMAGFSINTLTMFAMVLAIGLLVDDAIVVVENVERVM 420 N RATLIPTIAVPVVLLGTFAIL+ G+SINTLTMF MVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 SEEGLSPLEATRKSMDQITGALVGIGLTLSAVFVPMAFMSGSTGVIYRQFSITIVSAMAL 480 E+ L P EAT KSM QI GALVGI + LSAVF+PMAF GSTG IYRQFSITIVSAMAL Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLVALILTPALCATMLKPVKKGHGHIETGFFGWFNRTFDKLTNRYESSVAGIIKRSFRV 540 SVLVALILTPALCAT+LKPV H + GFFGWFN TFD N Y +SV I+ + R Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 Query: 541 MTIYVVLVIAVGWIFIRMPTAFLPDEDQGILFTQAILPTNSTQESTLKVLEKVSDHFMA- 599 + IY ++V + +F+R+P++FLP+EDQG+ T LP +TQE T KVL++V+D+++ Sbjct: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 Query: 600 -EEGVRSVFSVAGFSFAGQGQNMGIAFVGLKDWSEREAPGMDVKSIAGRAMGVFGQMKDA 658 + V SVF+V GFSF+GQ QN G+AFV LK W ER +++ RA G+++D Sbjct: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG 660 Query: 659 LVFAFVPPAVIELGTANGFDMYLQDKNGQGHEKLVAARNQLLGMAAQNP-NLVGVRPNGQ 717 V F PA++ELGTA GFD L D+ G GH+ L ARNQLLGMAAQ+P +LV VRPNG Sbjct: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 Query: 718 EDAPIYQLHVDHAKLSALGIEITNVNSVLATAWGGSYVNDFIDRGRVKKVYVQGDAQYRM 777 ED ++L VD K ALG+ ++++N ++TA GG+YVNDFIDRGRVKK+YVQ DA++RM Sbjct: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM 780 Query: 778 QPGDLDTWYVRNNKGDMVPFSAFATGTWEYGSPRLERFNGLPSMNIQGATAPGFSTGAAM 837 P D+D YVR+ G+MVPFSAF T W YGSPRLER+NGLPSM IQG APG S+G AM Sbjct: 781 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM 840 Query: 838 EIMEDLAKQLPPGFGVEWNGLSYEERLSGNQAPALYALSILVVFLVLAALYESWSVPFAV 897 +ME+LA +LP G G +W G+SY+ERLSGNQAPAL A+S +VVFL LAALYESWS+P +V Sbjct: 841 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900 Query: 898 VLVVPLGIIGALIAMNGRGLPNDVFFQVGLLTTVGLATKNAILIVEFAKEFYEK-GSGLV 956 +LVVPLGI+G L+A NDV+F VGLLTT+GL+ KNAILIVEFAK+ EK G G+V Sbjct: 901 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV 960 Query: 957 EATLHAVRVRLRPILMTSLAFGLGVVPLAISSGVGSGSQNAIGTAVLGGMMSSTFLGIFF 1016 EATL AVR+RLRPILMTSLAF LGV+PLAIS+G GSG+QNA+G V+GGM+S+T L IFF Sbjct: 961 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF 1020 Query: 1017 VPLFFVIVERIF 1028 VP+FFV++ R F Sbjct: 1021 VPVFFVVIRRCF 1032 Score = 78.3 bits (193), Expect = 1e-16 Identities = 75/523 (14%), Positives = 170/523 (32%), Gaps = 40/523 (7%) Query: 534 IKRSFRVMTIYVVLVIAVGWIFIRMPTAFLPDEDQGILFTQAILPTNSTQESTLKVLEKV 593 I+R + ++L++A +++P A P + A P Q V + + Sbjct: 6 IRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQVI 65 Query: 594 SDHFMAEEGVRSVFSVAGFSFAGQGQNMGIAFVGLKDWSEREAPGMDVKSIAGRAMGVFG 653 + + + + S S + + + F G D + Sbjct: 66 EQNMNGIDNLMYMSST---SDSAGSVTITLTF----------QSGTDPDIAQVQVQNKLQ 112 Query: 654 QMKDALVFAFVPPAVIELGTANGFDMYL----QDKNGQGHEKLVAARNQLLGMAAQNPNL 709 L + +++ + M + + + + ++ + Sbjct: 113 LATPLLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGV 172 Query: 710 VGVRPNGQEDAPIYQLHVDHAKLSALGIEITNVNSVLATA----WGGSYVNDFIDRGRVK 765 V+ G + A ++ +D L+ + +V + L G G+ Sbjct: 173 GDVQLFGAQYA--MRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQL 230 Query: 766 KVYVQGDAQYRMQPGDLDTWYVRNNK-GDMVPFSAFAT---GTWEYGSPRLERFNGLPSM 821 + +++ P + +R N G +V A G Y + R NG P+ Sbjct: 231 NASIIAQTRFK-NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNV--IARINGKPAA 287 Query: 822 NIQGATAPGFST----GAAMEIMEDLAKQLPPGFGVEWNGL---SYEERLSGNQAPALYA 874 + A G + A + +L P G ++ + +LS ++ Sbjct: 288 GLGIKLATGANALDTAKAIKAKLAELQPFFPQG--MKVLYPYDTTPFVQLSIHEVVKTLF 345 Query: 875 LSILVVFLVLAALYESWSVPFAVVLVVPLGIIGALIAMNGRGLPNDVFFQVGLLTTVGLA 934 +I++VFLV+ ++ + VP+ ++G + G + G++ +GL Sbjct: 346 EAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLL 405 Query: 935 TKNAILIVE-FAKEFYEKGSGLVEATLHAVRVRLRPILMTSLAFGLGVVPLAISSGVGSG 993 +AI++VE + E EAT ++ ++ ++ +P+A G Sbjct: 406 VDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGA 465 Query: 994 SQNAIGTAVLGGMMSSTFLGIFFVPLFFVIVERIFSKREKKAK 1036 ++ M S + + P + + S + K Sbjct: 466 IYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENK 508
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 41.0 bits (96), Expect = 6e-06 Identities = 19/102 (18%), Positives = 39/102 (38%), Gaps = 10/102 (9%) Query: 97 ATYKAALVSANADLARANAGLASAKAKAARYQQLVKTNAISKQEFDEAEAAYKEALANVT 156 L + L + + + SAK + QL K + K ++ N+ Sbjct: 262 VEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDK---------LRQTTDNIG 312 Query: 157 VAEAAINTAKINLQYTEVLAPISGRIGKSSV-TAGALVTANQ 197 + + + Q + + AP+S ++ + V T G +VT + Sbjct: 313 LLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAE 354 Score = 40.6 bits (95), Expect = 8e-06 Identities = 40/211 (18%), Positives = 77/211 (36%), Gaps = 52/211 (24%) Query: 43 VVAQPQVIQVELPGRSKAFLEAEVRPQVSGIITKRSFV-EGGNVKQGESLYQIDSATYKA 101 A ++ GRSK E++P + I+ K V EG +V++G+ L ++ + Sbjct: 84 ATANGKLT---HSGRSK-----EIKPIENSIV-KEIIVKEGESVRKGDVLLKLTA----- 129 Query: 102 ALVSANADLARANAGLASAKAKAARYQQLVKTNAISKQEFDEAEAAYKEALANVTVAEAA 161 + A AD + + L A+ + RYQ L + +I + E + + NV+ E Sbjct: 130 --LGAEADTLKTQSSLLQARLEQTRYQILSR--SIELNKLPELKLPDEPYFQNVSEEEVL 185 Query: 162 INTAKINLQYTEVLAPISGRIGKSSVTAGALVTANQSQTLATIQQLDPINVDIAQSSAQL 221 T+ I + Q Q +++ + A+ Sbjct: 186 RLTSLI-----------------------------KEQFSTWQNQKYQKELNLDKKRAER 216 Query: 222 LRLKAKL----KQGKLQASENADVQLLLEDG 248 L + A++ +++ S D LL Sbjct: 217 LTVLARINRYENLSRVEKSRLDDFSSLLHKQ 247
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 28.3 bits (63), Expect = 0.003 Identities = 8/34 (23%), Positives = 17/34 (50%) Query: 1 MVSHRRSKPEIQFNTPLNETQTPTINTSLMTNIA 34 ++ ++ N +NET + T+ T + T +A Sbjct: 234 LIKYKTMPLRDVMNLSVNETLSRTVMTGMTTLLA 267
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 28.6 bits (64), Expect = 0.022 Identities = 21/95 (22%), Positives = 31/95 (32%), Gaps = 11/95 (11%) Query: 97 FIGKAGEFG--DSGFTYDVMLFSYLYQGASYSNYTEL--WLKVGKQFGRANLQLEVTPTV 152 FIG G FG G V L + + +L V K + V Sbjct: 97 FIGLKGGFGKLRVGRLNSV-----LKDTGDINPWDSKSDYLGVNKIAEPEARLISVRYDS 151 Query: 153 DDWFGVDGWHGVNYALHPSYNFDNGVKISGSVGYQ 187 ++ G+ G V YAL+ + N Y+ Sbjct: 152 PEFAGLSG--SVQYALNDNAGRHNSESYHAGFNYK 184
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 29.4 bits (66), Expect = 0.025 Identities = 12/39 (30%), Positives = 17/39 (43%) Query: 78 PQTQLLRQTVGAEVAFAIENLGIPAEQMLPKVQLALRRV 116 + Q LR+ E+ E A M PKV A+R + Sbjct: 247 EKEQWLREVKVEELRKYYEEGHFKAGSMGPKVLAAIRFI 285
>cloacin#Cloacin signature. Length = 551 Score = 58.6 bits (141), Expect = 6e-11 Identities = 36/100 (36%), Positives = 42/100 (42%), Gaps = 3/100 (3%) Query: 383 GGTGTGGGTGTGGGTGTGGGTGTGGGTGTGGGTGTGGGTGT---GGGTGTGGGTGTGGGT 439 GG G G TG +G G TG G G G G+G + GGG+G+G G G G Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGH 62 Query: 440 GTGGGTGTGGGTGTGGGTGTGGGTGTGGGTGTGGGTGTGG 479 G GGG G GG GG + G G GG Sbjct: 63 GNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGG 102 Score = 58.6 bits (141), Expect = 6e-11 Identities = 36/100 (36%), Positives = 42/100 (42%), Gaps = 3/100 (3%) Query: 389 GGTGTGGGTGTGGGTGTGGGTGTGGGTGTGGGTGTGGGTGT---GGGTGTGGGTGTGGGT 445 GG G G TG +G G TG G G G G+G + GGG+G+G G G G Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGH 62 Query: 446 GTGGGTGTGGGTGTGGGTGTGGGTGTGGGTGTGGGTGTGG 485 G GGG G GG GG + G G GG Sbjct: 63 GNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGG 102 Score = 57.4 bits (138), Expect = 1e-10 Identities = 33/83 (39%), Positives = 39/83 (46%), Gaps = 3/83 (3%) Query: 407 GGTGTGGGTGTGGGTGTGGGTGTGGGTGTGGGTGTGGGTGT---GGGTGTGGGTGTGGGT 463 GG G G TG +G G TG G G G G+G + GGG+G+G G G G Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGH 62 Query: 464 GTGGGTGTGGGTGTGGGTGTGGA 486 G GGG G GG GG + A Sbjct: 63 GNGGGNGNSGGGSGTGGNLSAVA 85 Score = 55.1 bits (132), Expect = 6e-10 Identities = 35/99 (35%), Positives = 41/99 (41%), Gaps = 5/99 (5%) Query: 380 GSGGGTGTGGGTGTGGGTGTGGGTGTGGGTGTGGGTGT-----GGGTGTGGGTGTGGGTG 434 G G G TG + +G G G G GGG G G + GGG+G+G G G G G Sbjct: 4 GDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHG 63 Query: 435 TGGGTGTGGGTGTGGGTGTGGGTGTGGGTGTGGGTGTGG 473 GGG G GG GG + G G GG Sbjct: 64 NGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGG 102 Score = 53.2 bits (127), Expect = 2e-09 Identities = 34/96 (35%), Positives = 38/96 (39%), Gaps = 1/96 (1%) Query: 372 GSNNGGTIGSGGGTGTGGGTGTGGGTGTGGGTGTGGGTGTGGGTGTGGGTGTGGGTGTGG 431 G N G SG G G G GGG G G + GGG+G+G G G G G GG Sbjct: 8 GHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSEN-NPWGGGSGSGIHWGGGSGHGNGG 66 Query: 432 GTGTGGGTGTGGGTGTGGGTGTGGGTGTGGGTGTGG 467 G G GG GG + G G GG Sbjct: 67 GNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGG 102 Score = 52.0 bits (124), Expect = 7e-09 Identities = 33/93 (35%), Positives = 41/93 (44%), Gaps = 1/93 (1%) Query: 370 NTGSNNGGTIGSGGGTGTGGGTGTGGGTGTGG-GTGTGGGTGTGGGTGTGGGTGTGGGTG 428 NTG+++ +GG TG G G G G+G GGG+G+G G G G G GGG G Sbjct: 10 NTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNG 69 Query: 429 TGGGTGTGGGTGTGGGTGTGGGTGTGGGTGTGG 461 GG GG + G G GG Sbjct: 70 NSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGG 102 Score = 51.3 bits (122), Expect = 1e-08 Identities = 32/79 (40%), Positives = 39/79 (49%), Gaps = 6/79 (7%) Query: 377 GTIGSGGGTGTGGGTGTGGGTGTGGGTGTGGGTGTGGGT-----GTGGGTGTGGGTGTGG 431 G G G TG +G G TG G G G G+G + G G G+G G G+G Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGH 62 Query: 432 GTGTGGGTGTGGGTGTGGG 450 G G GG +GGG+GTGG Sbjct: 63 GNG-GGNGNSGGGSGTGGN 80 Score = 50.9 bits (121), Expect = 2e-08 Identities = 29/73 (39%), Positives = 35/73 (47%), Gaps = 3/73 (4%) Query: 419 GGTGTGGGTGTGGGTGTGGGTGTGGGTGTGGGTGTGGGTGT---GGGTGTGGGTGTGGGT 475 GG G G TG +G G TG G G G G+G + GGG+G+G G G G Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGH 62 Query: 476 GTGGGTGTGGAEN 488 G GGG G G + Sbjct: 63 GNGGGNGNSGGGS 75 Score = 37.8 bits (87), Expect = 2e-04 Identities = 25/69 (36%), Positives = 32/69 (46%), Gaps = 7/69 (10%) Query: 431 GGTGTGGGTGTGGGTGTGGGTGTGGGTGTGGGTGTGGGTGT---GGGTGTG----GGTGT 483 GG G G TG +G G TG G G G G+G + GGG+G+G GG+G Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGH 62 Query: 484 GGAENLNDS 492 G +S Sbjct: 63 GNGGGNGNS 71 Score = 36.6 bits (84), Expect = 3e-04 Identities = 21/63 (33%), Positives = 25/63 (39%) Query: 369 ANTGSNNGGTIGSGGGTGTGGGTGTGGGTGTGGGTGTGGGTGTGGGTGTGGGTGTGGGTG 428 ++ + GG GSG G G G G GGG G GG GG + G G Sbjct: 40 SSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPG 99 Query: 429 TGG 431 GG Sbjct: 100 AGG 102 Score = 32.0 bits (72), Expect = 0.010 Identities = 18/43 (41%), Positives = 23/43 (53%), Gaps = 1/43 (2%) Query: 360 WKSVVDTYTANTGSNNGGTIGSGGGTGTGGGTGTGGGTGTGGG 402 W S + + +GS GSG G G GG +GGG+GTGG Sbjct: 39 WSSENNPWGGGSGSGIHWGGGSGHGNG-GGNGNSGGGSGTGGN 80 Score = 30.8 bits (69), Expect = 0.020 Identities = 17/41 (41%), Positives = 21/41 (51%), Gaps = 1/41 (2%) Query: 368 TANTGSNNGGTIGSGGGTGTGGGTGTGGGTGTGGGTGTGGG 408 + N G G G G+G G G GG +GGG+GTGG Sbjct: 41 SENNPWGGGSGSGIHWGGGSGHGNG-GGNGNSGGGSGTGGN 80
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 30.3 bits (68), Expect = 0.002 Identities = 10/36 (27%), Positives = 20/36 (55%) Query: 80 VASDFRRLGLAQSLLEYQETWARRQGYNHIQVKTMN 115 VA D+R+ G+ +LL WA+ + + ++T + Sbjct: 97 VAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQD 132
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 449 bits (1157), Expect = e-157 Identities = 156/476 (32%), Positives = 239/476 (50%), Gaps = 43/476 (9%) Query: 13 SAVSVLIVDDEPGMRSFLNKALSKKFALVETAGSIEDAEQLRSRCHFDLLIVDIRLPGRS 72 + ++L+ DD+ +R+ LN+ALS+ V + + + DL++ D+ +P + Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 73 GIEWHEALDEQGRRSDIIFMTGYADMEVAITALRAGASDFIMKPFHLEQMMTAVDRCIER 132 + + + ++ M+ AI A GA D++ KPF L +++ + R + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 133 RLLKRENLMLRREVSIGYSSTIIGSSEAMKSVKHIIERVAPTNAVVLIQGESGTGKELVA 192 + L + + ++G S AM+ + ++ R+ T+ ++I GESGTGKELVA Sbjct: 122 PKRRPSKLEDDSQDGMP----LVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVA 177 Query: 193 RQLHLLSGR-QGPFVPVNCGSIAPELLESELFGHTAGAFTGAKGNREGLFSFASGGTIFL 251 R LH R GPFV +N +I +L+ESELFGH GAFTGA+ G F A GGT+FL Sbjct: 178 RALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFL 237 Query: 252 DEIGEMPLKMQTALLRVLEQKAIRPVGSEKEVNIDVRVIAATNRTLIDEVDAGNFRRDLY 311 DEIG+MP+ QT LLRVL+Q VG + DVR++AATN+ L ++ G FR DLY Sbjct: 238 DEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLY 297 Query: 312 YRLNVLDILIPPLRDRPEDVVELTHHFTRQLAAELGVREVVWSHEDMVKLQQHEWPGNIR 371 YRLNV+ + +PPLRDR ED+ +L HF +Q E G+ + E + ++ H WPGN+R Sbjct: 298 YRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKE-GLDVKRFDQEALELMKAHPWPGNVR 356 Query: 372 ELRNMIERCILL------------------------------------GKPPAEYWKQQL 395 EL N++ R L + E +Q Sbjct: 357 ELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYF 416 Query: 396 KS-ESLSTSGYPLDWPLKEVEKHHVTSVVDLHSGNKSAAARDLGVSRKTLDRKYKE 450 S D L E+E + + + GN+ AA LG++R TL +K +E Sbjct: 417 ASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRE 472