>PF00577#Outer membrane usher protein FimD Length = 878 Score = 254 bits (650), Expect = 3e-79 Identities = 87/387 (22%), Positives = 162/387 (41%), Gaps = 20/387 (5%) Query: 1 MAAWRYASQDYRTFSDHLYENDKINHQSDYD----------DFYNIG--RKNSLSANIMQ 48 + +RY++ Y F+D Y + D D+YN+ ++ L + Q Sbjct: 476 LVGYRYSTSGYFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQ 535 Query: 49 PLSNNLGNVSLSALWRNYWGRSGNAKDYQFSYSNSWQRISYTFSASQSYDENDKEEER-F 107 L + LS + YWG S + +Q + +++ I++T S S + + K ++ Sbjct: 536 QL-GRTSTLYLSGSHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQML 594 Query: 108 NLFISIPF--YWGDDIAKTRHQINLSNSTSFSKDGYSSNNTGITGIAGEHDQLNYGI--- 162 L ++IPF + D + S S S +G +N G+ G E + L+Y + Sbjct: 595 ALNVNIPFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTG 654 Query: 163 YVNQQQQNNDTSLGTNLSWRTPIAIIDGSYSHSKNAWQSGGSISSGLVVWSGGINITNQL 222 Y N+ ++ L++R + YSHS + Q +S G++ + G+ + L Sbjct: 655 YAGGGDGNSGSTGYATLNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPL 714 Query: 223 SDTFAILDEPGLEGAHINGQKYNRTNSKGQVVYDPIIPHRENHLVLDIANSESETELQGN 282 +DT ++ PG + A + Q RT+ +G V +REN + LD +L Sbjct: 715 NDTVVLVKAPGAKDAKVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNA 774 Query: 283 RQIIAPYRGAVSYVQFTTDQRKPWYIQALRPDGSPLTFGYDVLDLQENNIGVVGQGSRLF 342 + P RGA+ +F + L + PL FG V + G+V +++ Sbjct: 775 VANVVPTRGAIVRAEFKARVGIKLLMT-LTHNNKPLPFGAMVTSESSQSSGIVADNGQVY 833 Query: 343 IRVDEIPTGIKVALNDEQNLFCTITFQ 369 + + ++V +E+N C +Q Sbjct: 834 LSGMPLAGKVQVKWGEEENAHCVANYQ 860
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 30.7 bits (69), Expect = 0.002 Identities = 14/32 (43%), Positives = 19/32 (59%) Query: 8 NSAVLVHFTLKLDDGTTAESTRNNGKPALFRL 39 + V V +T L DGT +ST GKPA F++ Sbjct: 144 SDTVTVEYTGTLIDGTVFDSTEKAGKPATFQV 175
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 33.7 bits (77), Expect = 0.004 Identities = 25/143 (17%), Positives = 49/143 (34%), Gaps = 20/143 (13%) Query: 34 CKALREEGYRVILVNS-----------NPATIMTDPEMADATYIEPIHWEVVRKIIEKER 82 +AL GY V + ++ + ++TD M D + + I+K R Sbjct: 20 NQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD------LLPRIKKAR 73 Query: 83 PDAVLPTMGGQTALNCALELERQGVLEEFGVTM-IGATADAIDKAEDRRRFDVAMKKIGL 141 PD + M Q A++ +G + + I +A + + + Sbjct: 74 PDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPSKLEDDS 133 Query: 142 ETARSGIAHS--MEEALAVAAEV 162 + + S M+E V A + Sbjct: 134 QDGMPLVGRSAAMQEIYRVLARL 156
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 32.1 bits (73), Expect = 0.006 Identities = 20/103 (19%), Positives = 40/103 (38%), Gaps = 18/103 (17%) Query: 300 ILIADKQSVGERAVKGICGQVDGSVV------PGFIGLEAGQS-AFGDIYAWFGRVLGWP 352 + I++K+ + + + ++G + G I + + + G P Sbjct: 281 VRISEKEKIK---ITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSV---LGDTKLLP 334 Query: 353 L-EQLAAQHPELKTQINASQKQ----LLPALTEAWAKNPSLDH 390 E++ P L+T + S+ Q LL AL E +P L + Sbjct: 335 QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRY 377
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 28.9 bits (64), Expect = 0.022 Identities = 26/118 (22%), Positives = 47/118 (39%), Gaps = 21/118 (17%) Query: 82 YGRHPEAREWYHQWVYFRPRAYWHEWLNWPSIFANTGFFRPDEAHQPHFSDLFGQ-IINA 140 Y R PE +E + R YW + N P ++ +F+ + +F G ++ Sbjct: 158 YSRFPEVKELMESQMERLARPYWEKLRNRPDMY----YFKNYNFKRCYFGLNGGDCLVAK 213 Query: 141 G-----------QGEGRYSELLAINLLEQLLLRRMEA-----INESLHPPMDNRVREA 182 G QG +Y E + LE++L +++A I + +P +V A Sbjct: 214 GDDGRTFISFSLQGNSKYKEEMDAKKLEEILSLKVDANPDKYIKATGYPGYSEKVEVA 271
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.1 bits (73), Expect = 0.007 Identities = 15/60 (25%), Positives = 29/60 (48%), Gaps = 2/60 (3%) Query: 119 EVTEILVKVGDKV-EAEQSLITVEGDKASMEVPAPFAGTVKEIKVN-VGDKVSTGSLIMV 176 E+ + L + D + L E + + + AP + V+++KV+ G V+T +MV Sbjct: 299 EILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMV 358 Score = 31.7 bits (72), Expect = 0.008 Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 2/63 (3%) Query: 26 DKVEAEQSLITVEGDKASMEVPSPQAGIVKEIKVSVGDKTQTGALIMIFDSADGAADAAP 85 + V +T G S E+ + IVKEI V G+ + G +++ + AD Sbjct: 81 EIVATANGKLTHSGR--SKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLK 138 Query: 86 AQA 88 Q+ Sbjct: 139 TQS 141 Score = 30.6 bits (69), Expect = 0.019 Identities = 14/60 (23%), Positives = 28/60 (46%), Gaps = 2/60 (3%) Query: 220 EVTEVMVKVGDKVAA-EQSLITVEGDKASMEVPAPFAGVVKELKVN-VGDKVKTGSLIMI 277 E+ + + + D + L E + + + AP + V++LKV+ G V T +M+ Sbjct: 299 EILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMV 358 Score = 29.8 bits (67), Expect = 0.035 Identities = 20/95 (21%), Positives = 35/95 (36%), Gaps = 3/95 (3%) Query: 230 DKVAAEQSLITVEGDKASMEVPAPFAGVVKELKVNVGDKVKTGSLIMIFEVEGAAPAAAP 289 + VA +T G S E+ +VKE+ V G+ V+ G +++ GA A Sbjct: 81 EIVATANGKLTHSGR--SKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAE-ADTL 137 Query: 290 AKQEAAAPAPAAKAEAPAAAPAAKAEGKSEFAEND 324 Q + A + + + + E D Sbjct: 138 KTQSSLLQARLEQTRYQILSRSIELNKLPELKLPD 172
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 29.2 bits (65), Expect = 0.022 Identities = 26/99 (26%), Positives = 39/99 (39%), Gaps = 20/99 (20%) Query: 110 MVKIEGGEWL----VETVQMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEAGDQL-L 164 V +E G L + V L AV GL P +V + D++G L Sbjct: 176 TVTLEPGRALDEGQISAVVHLVSSAVA-----GLPPGNVTLV---------DQSGHLLTQ 221 Query: 165 SDALALEAAGAQLLVLECVPVELAKRITEALAIPVIGIG 203 S+ + AQL V + +RI L+ P++G G Sbjct: 222 SNTSGRDLNDAQLKFANDVESRIQRRIEAILS-PIVGNG 259
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 792 bits (2048), Expect = 0.0 Identities = 271/870 (31%), Positives = 432/870 (49%), Gaps = 40/870 (4%) Query: 14 RIATFCALLYCNTAFSAELVEYDHTFLMGQNASNIDLSRYSEGNPAIPGVYDVSVYVNDQ 73 R+ CA SAE + ++ FL + DLSR+ G PG Y V +Y+N+ Sbjct: 29 RLFVACAFAAQAPLSSAE-LYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNG 87 Query: 74 PIINQSITFVAIEGKKNAQACITLKNLLQFHINSPDINNEKAVLLARDETLGNCLNLTEI 133 + + +TF + ++ C+T L +N+ + LLA D C+ LT + Sbjct: 88 YMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASV--SGMNLLADDA----CVPLTSM 141 Query: 134 IPQASVRYDVNDQRLDIDVPQAWVMKNYQNYVDPSLWENGINAAMLSYNLNGYHSETP-G 192 I A+ + DV QRL++ +PQA++ + Y+ P LW+ GINA +L+YN +G + G Sbjct: 142 IHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIG 201 Query: 193 RKNESIYAAFNGGMNLGAWRLRASGNYNWMTDSGS-----NYDFKNRYVQRDIASLRSQL 247 + Y G+N+GAWRLR + +++ + S + N +++RDI LRS+L Sbjct: 202 GNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRL 261 Query: 248 ILGESYTTGETFDSVSIRGIRLYSDSRMLPPTLASFAPIIHGVANTNAKVTITQGGYKIY 307 LG+ YT G+ FD ++ RG +L SD MLP + FAP+IHG+A A+VTI Q GY IY Sbjct: 262 TLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIY 321 Query: 308 ETTVPPGAFVIDDLSPSGYGSDLIVTIEESDGSKRTFSQPFSSVVQMLRPGVGRWDISGG 367 +TVPPG F I+D+ +G DL VTI+E+DGS + F+ P+SSV + R G R+ I+ G Sbjct: 322 NSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAG 381 Query: 368 QVLKDD-IQDEPNLFQASYYYGLNNYLTGYTGIQITDNNYTAGLLGLGLNT-SVGAFSFD 425 + + Q++P FQ++ +GL T Y G Q+ D Y A G+G N ++GA S D Sbjct: 382 EYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLAD-RYRAFNFGIGKNMGALGALSVD 440 Query: 426 VTHSNVRIPDDKTYQGQSYRVSWNKLFEETSTSLNIAAYRYSTQNYLGLNDALTLIDEVK 485 +T +N +PDD + GQS R +NK E+ T++ + YRYST Y D Sbjct: 441 MTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGY 500 Query: 486 HPE-----QDLEPKFMRNYSRM---KNQVTVSINQPLKFEKKDYGSFYLSGSWSDYWASG 537 + E ++PKF Y+ + ++ +++ Q L + YLSGS YW + Sbjct: 501 NIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQL----GRTSTLYLSGSHQTYWGTS 556 Query: 538 QNRSNYSIGYSNSTSWGSYSVSAQRSWNE-DGDTDDSVYLSFTIPIEKLLGTEQRTS-GF 595 + G + + ++++S + N D + L+ IP L ++ ++ Sbjct: 557 NVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRH 616 Query: 596 QSIDTQISSDFKGNNQLNVSSSGYS-DNARVSYSVNTGYTMNKASKDLSYVGGYASYESP 654 S +S D G G ++ +SYSV TGY S +Y Sbjct: 617 ASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGG 676 Query: 655 WGTLAGSISANSDNSRQVSLSTDGGFVLHSGGLTFSNDSFSDSDTLAVVQAPGAQGARIN 714 +G S + D +Q+ GG + H+ G+T +DT+ +V+APGA+ A++ Sbjct: 677 YGNANIGYSHSDDI-KQLYYGVSGGVLAHANGVTLGQPL---NDTVVLVKAPGAKDAKVE 732 Query: 715 YGNST-IDRWGYGVTSALSPYHENRIALDINDLENDVELKSTSAVAVPRQGSVVFADFET 773 D GY V + Y ENR+ALD N L ++V+L + A VP +G++V A+F+ Sbjct: 733 NQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKA 792 Query: 774 VQGQSAIMNITRSDGKNIPFAADIYDEQGNVIGNVGQGGQAFVRGIEQQGNISIKWLEQS 833 G +M +T + K +PF A + E G V GQ ++ G+ G + +KW E+ Sbjct: 793 RVGIKLLMTLTH-NNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEE 851 Query: 834 KPVSCLAHYQQSPEAEKIAQSIILNGIRCQ 863 C+A+YQ P + L+ C+ Sbjct: 852 NA-HCVANYQL-PPESQQQLLTQLSA-ECR 878
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 511 bits (1318), Expect = 0.0 Identities = 296/296 (100%), Positives = 296/296 (100%) Query: 1 MSGLPLISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGIVPYGVA 60 MSGLPLISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGIVPYGVA Sbjct: 1 MSGLPLISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGIVPYGVA 60 Query: 61 DTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGR 120 DTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGR Sbjct: 61 DTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGR 120 Query: 121 GFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLT 180 GFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLT Sbjct: 121 GFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLT 180 Query: 181 TLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDH 240 TLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDH Sbjct: 181 TLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDH 240 Query: 241 DNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVRVLDNAIGGKA 296 DNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVRVLDNAIGGKA Sbjct: 241 DNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVRVLDNAIGGKA 296
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 34.3 bits (78), Expect = 4e-04 Identities = 12/55 (21%), Positives = 28/55 (50%), Gaps = 4/55 (7%) Query: 186 NDYYRKVKELRAKNQITLPVILKNERQINVFLRT----EDIDLINVINEETLLQQ 236 + ++ EL A N T+ +K ++N+ +R D + I V +E+++++ Sbjct: 589 QNIKNQLAELNATNIYTVLDKIKLNAKMNILIRDKRFHYDRNNIAVGADESVVKE 643
>PF01206#SirA family protein Length = 76 Score = 30.5 bits (69), Expect = 0.001 Identities = 15/58 (25%), Positives = 32/58 (55%), Gaps = 1/58 (1%) Query: 58 PLTLDVAKKILSPITSFDYIHFITTHPSGIKDTLAWLVNAG-KLMTEFDDNGKIIFNL 114 PL + AKK L+ + + + ++ + T P +KD ++ G +L+ + +++G F L Sbjct: 16 PLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKEEDGTYHFRL 73
>PF06580#Sensor histidine kinase Length = 349 Score = 31.8 bits (72), Expect = 0.016 Identities = 15/95 (15%), Positives = 29/95 (30%), Gaps = 9/95 (9%) Query: 18 RPAMPRFKVSAFWLLILAWIFL-LVWIWWKGPTWTLYEEQWLKPLANRWLATAAWG---- 72 + + ++ A + + +VW W L KP+A + Sbjct: 66 QGWLKLNMGQIILRVLPACVVIGMVWFVANTSIWRLLAFINTKPVAFTLPLALSIIFNVV 125 Query: 73 IIALMW----LTVRVMKRLQQLEKMQKQQREEAVD 103 ++ MW K +Q E Q + A + Sbjct: 126 VVTFMWSLLYFGWHFFKNYKQAEIDQWKMASMAQE 160
>OUTRSURFACE#Outer surface protein signature. Length = 273 Score = 37.2 bits (86), Expect = 4e-04 Identities = 34/147 (23%), Positives = 60/147 (40%), Gaps = 21/147 (14%) Query: 536 DGTGVRRRITRNRYGQLLAFTDCSGYTTRYEYDQYGQQIA---VHREEGISTYSSYNPRG 592 +G+GV ++ L D TT + + G+ + V ++ ST +N +G Sbjct: 71 NGSGVLEGTKDDKSKAKLTIADDLSKTTFELFKEDGKTLVSRKVSSKDKTSTDEMFNEKG 130 Query: 593 QLISRKDAQGRETRYEYSAAGDLTATISPDGKRSATEYDKR----------GRPVSVTEG 642 +L ++ + T+ EY+ + DG A E K + V EG Sbjct: 131 ELSAKTMTRENGTKLEYT-------EMKSDGTGKAKEVLKNFTLEGKVANDKVTLEVKEG 183 Query: 643 GLTRSMGYDAAGRITV-LTNENGSQST 668 +T S +G +TV L + N +Q+T Sbjct: 184 TVTLSKEIAKSGEVTVALNDTNTTQAT 210
>ENTSNTHTASED#Enterobactin synthetase component D signature. Length = 234 Score = 26.9 bits (59), Expect = 0.011 Identities = 6/23 (26%), Positives = 10/23 (43%) Query: 45 AVYKDHPLQGSWKGYRDAHVEPD 67 +VYK + + G+ A V Sbjct: 153 SVYKAFSDRVTLPGFNSAKVTSL 175
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 38.0 bits (88), Expect = 1e-05 Identities = 30/118 (25%), Positives = 46/118 (38%), Gaps = 22/118 (18%) Query: 71 FERGSAKIMPFFKTLLVELAPVFDSL---DNKIIITGHTDAM---AYKNNIYNNWNLSGD 124 F A + P + L +L +L D +++ G+TD + AY N LS Sbjct: 223 FNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAY------NQGLSER 276 Query: 125 RALSARRVLEEAGMPEDKVMQVS-----AMADQMLLDSKNPQS-----AGNRRIEIMV 172 RA S L G+P DK+ + + K + A +RR+EI V Sbjct: 277 RAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEV 334
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 549 bits (1415), Expect = 0.0 Identities = 232/384 (60%), Positives = 269/384 (70%), Gaps = 34/384 (8%) Query: 1 MKKSTLALVVMGIVASASVQAAEIYNKDGNKLDVYGKVKAMHYMSDNASKDGDQSYIRFG 60 MK+ LALV+ ++A+ + AAEIYNKDGNKLD+YGKV +HY SD++SKDGDQ+Y+R G Sbjct: 1 MKRKVLALVIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSDDSSKDGDQTYMRVG 60 Query: 61 FKGETQINDQLTGYGRWEAEFAGNKAESDTAQQKTRLAFAGLKYKDLGSFDYGRNLGALY 120 FKGETQINDQLTGYG+WE N E + A TRLAFAGLK+ D GSFDYGRN G LY Sbjct: 61 FKGETQINDQLTGYGQWEYNVQANTTEGEGANSWTRLAFAGLKFGDYGSFDYGRNYGVLY 120 Query: 121 DVEAWTDMFPEFGGDSSAQTDNFMTKRASGLATYRNTDFFGVIDGLNLTLQYQGKNEN-- 178 DVE WTDM PEFGGDS DN+MT RA+G+ATYRNTDFFG++DGLN LQYQGKNE+ Sbjct: 121 DVEGWTDMLPEFGGDSYTYADNYMTGRANGVATYRNTDFFGLVDGLNFALQYQGKNESQS 180 Query: 179 --------------RDVKKQNGDGFGTSLTYDFGGSDFSISGAYTNSDRTNEQNLQSR-- 222 D++ NGDGFG S TYD G FS AYT SDRTNEQ Sbjct: 181 ADDVNIGTNNRNNGDDIRYDNGDGFGISTTYDI-GMGFSAGAAYTTSDRTNEQVNAGGTI 239 Query: 223 GTGKRAEAWATGLKYDANNIYLATFYSETRKMTP-------ITGGFANKTQNFEAVAQYQ 275 G +A+AW GLKYDANNIYLAT YSETR MTP GG ANKTQNFE AQYQ Sbjct: 240 AGGDKADAWTAGLKYDANNIYLATMYSETRNMTPYGKTDKGYDGGVANKTQNFEVTAQYQ 299 Query: 276 FDFGLRPSLGYVLSKGKDIE----GIGDEDLINYIDVGATYYFNKNMSAFVDYKINQLDS 331 FDFGLRP++ +++SKGKD+ D+DL+ Y DVGATYYFNKN S +VDYKIN LD Sbjct: 300 FDFGLRPAVSFLMSKGKDLTYNNVNGDDKDLVKYADVGATYYFNKNFSTYVDYKINLLDD 359 Query: 332 DNKL----NINNDDIVAVGMTYQF 351 D+ I+ DDIVA+GM YQF Sbjct: 360 DDPFYKDAGISTDDIVALGMVYQF 383
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 37.5 bits (87), Expect = 6e-05 Identities = 28/127 (22%), Positives = 48/127 (37%), Gaps = 17/127 (13%) Query: 119 DTLRALLDNNI---------VPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLT 169 +T++ L++ + VPVI E+ + E V D D A AD ++LT Sbjct: 177 ETIKKLVERGVIVIASGGGGVPVILEDGEIKGVE-AVIDKDLAGEKLAEEVNADIFMILT 235 Query: 170 DQKGLYTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKLQAA-DVACRAG 228 D G + + +++V +++ + G M K+ AA G Sbjct: 236 DVNGAALY--YGTEKEQWLREV-KVEELRKYYEEG---HFKAGSMGPKVLAAIRFIEWGG 289 Query: 229 IDTIIAA 235 IIA Sbjct: 290 ERAIIAH 296 Score = 30.2 bits (68), Expect = 0.013 Identities = 16/76 (21%), Positives = 33/76 (43%), Gaps = 13/76 (17%) Query: 4 SQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQ----LHAAGHRIVIVTSG-------- 51 + +V+ LG + L ++ + +++ VR+ A+ + A G+ +VI Sbjct: 2 GKRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSLL 61 Query: 52 -AIAAGREHLGYPELP 66 + AG+ G P P Sbjct: 62 LHMDAGQATYGIPAQP 77
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 63.3 bits (154), Expect = 3e-12 Identities = 38/316 (12%), Positives = 93/316 (29%), Gaps = 33/316 (10%) Query: 487 TLNLNSLWSKLGTFSISYNDDRRYNSHYYTADYYQNVYSGTFGSLGLRAGIQRYNNGDSN 546 L + + T +S + Y + +Q + F + N Sbjct: 530 QLTVTQQLGRTSTLYLSG-SHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQK 588 Query: 547 ANTGKYIALDLSLPLGNWFSAGMTHQNGYTMANLSARKQFDEGT------------IRTV 594 + +AL++++P +W + Q + A+ S + + Sbjct: 589 -GRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNL 647 Query: 595 GANLSRAISGDTGDDKTLSGGAYAQFDARYASGTLNVNSAADGYVNTNLTANGSVGWQGK 654 ++ +G + +G A + Y + + S +D +G V Sbjct: 648 SYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIGY-SHSDDIKQLYYGVSGGVLAHAN 706 Query: 655 NIAASGRTDGNAGVIFNTGLED---DGQISAKINGRIFPLNGKRNYLPLSPYGRYEVELQ 711 + + ++ G +D + Q + + R G + Y V L Sbjct: 707 GVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTDWR-----GYAVLPYATEYRENRVALD 761 Query: 712 NSKNSLDSYDIVSGRKSRLTLYPGNVAVIEPEVKQMVTVSGRIRAEDGTLLANARINNHI 771 + + + D+ + + G + E + + + + + + L A + Sbjct: 762 TNTLADN-VDLDNAVA-NVVPTRGAIVRAEFKARVGIKLLMTLTHNNKPLPFGAMV---- 815 Query: 772 GRTRTDENGEFVMDVD 787 T E+ + V Sbjct: 816 ----TSESSQSSGIVA 827
>INTIMIN#Intimin signature. Length = 939 Score = 560 bits (1443), Expect = 0.0 Identities = 233/818 (28%), Positives = 362/818 (44%), Gaps = 49/818 (5%) Query: 41 PVMAARAQHAVQPRLSMGNTTVTADNNVEKNVASFAANAGTFLSSQPDS-----DATRNF 95 P++AA +L+ + VT N + ++AA L SQ S D ++ Sbjct: 131 PLVAAGGVAGHTNKLTKMSPDVTKSNMTDDKALNYAAQQAASLGSQLQSRSLNGDYAKDT 190 Query: 96 ITGMATAKANQEIQEWLGKYGTARVKLNVDKDFSLKDSSLEMLYPIYDTPTNMLFTQGAI 155 G+A +A+ ++Q WL YGTA V L +F SSL+ L P YD+ + F Q Sbjct: 191 ALGIAGNQASSQLQAWLQHYGTAEVNLQSGNNFD--GSSLDFLLPFYDSEKMLAFGQVGA 248 Query: 156 HRTDDRTQSNIGFGWRHFSGNDWMAGVNTFIDHDLSRSHTRIGVGAEYWRDYLKLSANGY 215 D R +N+G G R F M G N FID D S +TR+G+G EYWRDY K S NGY Sbjct: 249 RYIDSRFTANLGAGQRFFLPE-NMLGYNVFIDQDFSGDNTRLGIGGEYWRDYFKSSVNGY 307 Query: 216 IRASGWKKSPDIEDYQERPANGWDIRAEGYLPAWPQLGASLMYEQYYGDEVGLFGKDKRQ 275 R SGW +S + +DY ERPANG+DIR GYLP++P LGA LMYEQYYGD V LF DK Q Sbjct: 308 FRMSGWHESYNKKDYDERPANGFDIRFNGYLPSYPALGAKLMYEQYYGDNVALFNSDKLQ 367 Query: 276 KDPHAISAEVTYTPVPLLTLSAGHKQGKSGENDTRFGLEVNYRIGEPLAKQLDTDSIRER 335 +P A + V YTP+PL+T+ ++ G END + ++ Y+ +P ++Q++ + E Sbjct: 368 SNPGAATVGVNYTPIPLVTMGIDYRHGTGNENDLLYSMQFRYQFDKPWSQQIEPQYVNEL 427 Query: 336 RVLAGSRYDLVERNNNIVLEYRKSEVIRIALPERIEGKGGQTLSLGLVVSKATHGLKNVQ 395 R L+GSRYDLV+RNNNI+LEY+K +++ + +P I G T + L+V K+ +GL + Sbjct: 428 RTLSGSRYDLVQRNNNIILEYKKQDILSLNIPHDINGTERSTQKIQLIV-KSKYGLDRIV 486 Query: 396 WEAPSLLAEGGKITGQGSQ----WQVTLPAYRPGKDNYYAISAVAYDNKGNASKRVQTEV 451 W+ +L ++GG+I GSQ +Q LPAY G N Y ++A AYD GN+S V + Sbjct: 487 WDDSALRSQGGQIQHSGSQSAQDYQAILPAYVQGGSNVYKVTARAYDRNGNSSNNVLLTI 546 Query: 452 VITGAGMSADRTALTLDGQSRIQMLANGNEQRPLVLSLRDAEGQPVTGTKDQIKTELAFK 511 + G D+ +T + A+G E +T T K +A Sbjct: 547 TVLSNGQVVDQVGVTDFTADKTSAKADGTE--------------AITYTATVKKNGVA-- 590 Query: 512 PAGNIVTRSLKATKSQAKPTLGEFTETEAGVYQSVFTTGTQSGEATITVSVDGMSKTVTA 571 A V S A + +G + G+ ++ M+ + A Sbjct: 591 QANVPV--SFNIVSGTAVLSANSANTNGSGKATVTLKSDK-PGQVVVSAKTAEMTSALNA 647 Query: 572 ELRATMMDVANSTLSANEPSGDVVADGQQAYTLTLTAVDSEGNPVTGEASRLRFVPQDTN 631 + S VA+GQ A T T+ V PV+ + T Sbjct: 648 NAVIFVDQTKASITEIKADKTTAVANGQDAITYTVK-VMKGDKPVSNQEVTF-----TTT 701 Query: 632 GVTVGAIS--EIKPGVYSATVSSTRAGNVVVRAFSEQYQLGTLQQTLKFVAGP-LDAAHS 688 + + G T++ST G +V A + ++F +D + Sbjct: 702 LGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNI 761 Query: 689 SITLNPDKPVVGGTVTAIWTAKDAYDNPVTSLTPE---APSLAGAAAVGSTASGWTNNGD 745 I V G + +W + + + + A+V +++ T Sbjct: 762 EIVGTG----VKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPAIASVDASSGQVTLKEK 817 Query: 746 GTWTAQITLGSTAGELEVMPKLNGQDAAANAAKVTVVADALSSNQSKVSVAEDHVKAGES 805 GT T + + N N +K DA+++ ++ E+ Sbjct: 818 GTTTISVISSDNQTATYTIATPNSL-IVPNMSKRVTYNDAVNTCKNFGGKLPSSQNELEN 876 Query: 806 TTVTLIAKDAHGNTISGLSLSASLTGTASEGATVSSWT 843 A + + S ++ + + TA + + + T Sbjct: 877 VFKAWGAANKYEYYKSSQTIISWVQQTAQDAKSGVAST 914 Score = 76.6 bits (188), Expect = 4e-16 Identities = 75/372 (20%), Positives = 124/372 (33%), Gaps = 51/372 (13%) Query: 882 TVIAGEMSSANSTLVADNKAPTVKMTTELTFTVKDAYGNPVTGLKPDAPVFSGAASTGSE 941 V + ++ ++ AD + T + PV+ + SG A Sbjct: 557 QVGVTDFTADKTSAKADGTEA-ITYTATVKKNGVAQANVPVSFN-----IVSGTAV---- 606 Query: 942 RPSAGNWTEKGNGVYVATLTLGSAAGQLSVMPRVNGQNAVAQPLVLNVAGDASKAEIRDM 1001 SA + G+G TL + +A+ V+ V D +KA I ++ Sbjct: 607 -LSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFV--DQTKASITEI 663 Query: 1002 TVKVNNQLANGQSANQITLTV-VDSYGNPLQGQEVTLTLPQGVTSKTGNTVTTNAAGKVD 1060 +ANGQ A IT TV V P+ QEVT T G S + T T+ G Sbjct: 664 KADKTTAVANGQDA--ITYTVKVMKGDKPVSNQEVTFTTTLGKLSNS--TEKTDTNGYAK 719 Query: 1061 IELMSTVAGEHSITASVNNAQ---KTVTVKFKADFS--TGQATLE---VDGSTPKVANDN 1112 + L ST G+ ++A V++ K V+F + G + V G P V Sbjct: 720 VTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGTGVKGKLPTVWLQY 779 Query: 1113 DAFTLTATVKDQYGNLLPGAVVVFNLPRGVKPLADGNIMVNADKEGKAELKVVSVTAGTY 1172 L A+ G + A+ I G+ LK GT Sbjct: 780 GQVNLKAS----------GGNGKYTW-----RSANPAIASVDASSGQVTLK----EKGTT 820 Query: 1173 EITASAGNDQPSNAQSVTFVADKTTATISSIEVIGNRAVADGKTKQTYKVTVTDANNNLL 1232 I+ + ++Q T+ + I + D ++ N L Sbjct: 821 TISVISSDNQT-----ATYTIATPNSLI-VPNMSKRVTYNDAVNTCKNFGGKLPSSQNEL 874 Query: 1233 KDSDVTLTASSE 1244 ++ A+++ Sbjct: 875 ENVFKAWGAANK 886 Score = 54.7 bits (131), Expect = 3e-09 Identities = 57/366 (15%), Positives = 104/366 (28%), Gaps = 52/366 (14%) Query: 779 VTVVADALSSNQSKV---SVAEDHVKAGESTTVTLIA------KDAHGNTISGLSLSASL 829 +TV+++ +Q V + + KA + +T A +S +S Sbjct: 546 ITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKNGVAQANVPVSFNIVS--- 602 Query: 830 TGTASEGATVSSWTEKGDCSYVATLTTGGKTGELRVMPLFNGQPAATEAAQLTVIAGEMS 889 GTA A +S G TL + + A A + + Sbjct: 603 -GTAVLSA--NSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALN--ANAVIFVDQTK 657 Query: 890 SANSTLVADNKAPTVKMTTELTFTVKDAY-GNPVTGLKPDAPVFSGAASTGSERPSAGNW 948 ++ + + AD +T+TVK PV+ + +T + S Sbjct: 658 ASITEIKADKTTAVANGQDAITYTVKVMKGDKPVSNQEV-------TFTTTLGKLSNSTE 710 Query: 949 TEKGNGVYVATLTLGSAAGQLSVMPRVNGQN-AVAQPLVLNVAG---DASKAEIRDMTVK 1004 NG TLT + G+ V RV+ V P V D EI Sbjct: 711 KTDTNGYAKVTLT-STTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEI------ 763 Query: 1005 VNNQLANGQSANQITLTV-VDSYGNPLQGQEVTLTLPQGVTSKTGNTVTTNAAGKVDIEL 1063 + G T+ + G T ++ ++G+V ++ Sbjct: 764 ----VGTGVKGKLPTVWLQYGQVNLKASGGNGKYTW---RSANPAIASVDASSGQVTLK- 815 Query: 1064 MSTVAGEHSITASVNNAQKTVTVKFKADFSTGQATLEVDGSTPKVANDNDAFTLTATVKD 1123 G +I+ ++ Q T + + + + Sbjct: 816 ---EKGTTTISVISSDNQ---TATYTIATPNSLIVPNMSKRV-TYNDAVNTCKNFGGKLP 868 Query: 1124 QYGNLL 1129 N L Sbjct: 869 SSQNEL 874 Score = 51.2 bits (122), Expect = 3e-08 Identities = 38/178 (21%), Positives = 64/178 (35%), Gaps = 12/178 (6%) Query: 1168 TAGTYEITASA----GNDQPSNAQSVTFVADKTTAT---ISSIEVIGNRAVADGKTKQTY 1220 + Y++TA A GN + ++T +++ ++ A ADG TY Sbjct: 521 GSNVYKVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITY 580 Query: 1221 KVTVTDANNNLLKDSDVTLTASSENLVLDPKGTAKTNEQGQAVFTGSTTIAATYTLTAKV 1280 TV S + +A TN G+A T + ++AK Sbjct: 581 TATVKKNGVAQANVPVSFNIVS--GTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAK- 637 Query: 1281 EQANGQVSTKTAESKFVADDKNAVLAASPERVDSLVADGKTTATMTVTLMAGVNPVGG 1338 A + FV K ++ ++ + VA+G+ T TV +M G PV Sbjct: 638 -TAEMTSALNANAVIFVDQTKASITEIKADK-TTAVANGQDAITYTVKVMKGDKPVSN 693
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 28.4 bits (63), Expect = 0.023 Identities = 12/42 (28%), Positives = 19/42 (45%) Query: 3 RQKILQQLLEWIECNLEHPISIEDIAQKSGYSRRNIQLLFRN 44 RQ IL L S+ +IA+ +G +R I F++ Sbjct: 13 RQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKD 54
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.6 bits (69), Expect = 0.009 Identities = 15/50 (30%), Positives = 24/50 (48%), Gaps = 2/50 (4%) Query: 6 TEENLLAFTTAARFGSFSKAAEELGLTTSAISYTIKRMETGLDVVLFTRS 55 E L+ A G+ KAA+ LGL + + I+ + G+ V +RS Sbjct: 436 MEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIREL--GVSVYRSSRS 483
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 435 bits (1119), Expect = e-156 Identities = 139/315 (44%), Positives = 201/315 (63%), Gaps = 3/315 (0%) Query: 1 MKELVVVAIGGNSIIKDNASQSIEHQAEAVKAVADTVLEMLASDYDIVLTHGNGPQVGLD 60 M + VV+A+GGN++ + S E + V+ A + E++A Y++V+THGNGPQVG Sbjct: 1 MGKRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSL 60 Query: 61 LRRAEIAHKREGLPLTPLANCVADTQGGIGYLIQQALNNRLARHG-EKKAVTVVTQVEVD 119 L + G+P P+ A +QG IGY+IQQAL N L + G EKK VT++TQ VD Sbjct: 61 LLHMDAGQATYGIPAQPMDVAGAMSQGWIGYMIQQALKNELRKRGMEKKVVTIITQTIVD 120 Query: 120 KNDPGFAHPTKPIGAFFSDSQRDELQKANPDWCFVEDAGRGYRRVVASPEPKRIVEAPAI 179 KNDP F +PTKP+G F+ + L + W ED+GRG+RRVV SP+PK VEA I Sbjct: 121 KNDPAFQNPTKPVGPFYDEETAKRLAREK-GWIVKEDSGRGWRRVVPSPDPKGHVEAETI 179 Query: 180 KALIQQGFVVIGAGGGGIPVVRTDAGDYQSVDAVIDKDLSTALLAREIHADILVITTGVE 239 K L+++G +VI +GGGG+PV+ D G+ + V+AVIDKDL+ LA E++ADI +I T V Sbjct: 180 KKLVERGVIVIASGGGGVPVILED-GEIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVN 238 Query: 240 KVCIHFGKPQQQALDRVDIATMTRYMQEGHFPPGSMLPKIIASLTFLEQGGKEVIITTPE 299 +++G ++Q L V + + +Y +EGHF GSM PK++A++ F+E GG+ II E Sbjct: 239 GAALYYGTEKEQWLREVKVEELRKYYEEGHFKAGSMGPKVLAAIRFIEWGGERAIIAHLE 298 Query: 300 CLPAALRGETGTHII 314 AL G+TGT ++ Sbjct: 299 KAVEALEGKTGTQVL 313
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 342 bits (878), Expect = e-114 Identities = 121/401 (30%), Positives = 200/401 (49%), Gaps = 54/401 (13%) Query: 164 DLAEEAGMTGIFIYSAATVRQAFSDALDMTRMSLRHNTHDATRNALRTRYVLGDMLGQSP 223 A +A G + Y ++ + + +L ++ ++G+S Sbjct: 88 MTAIKASEKGAYDYLPKPFDL--TELIGIIGRALAEPKRRPSK-LEDDSQDGMPLVGRSA 144 Query: 224 QMEQVRQTILLYARSSAAVLIEGETGTGKELAAQAIHREYFARHDARQGKKSHPFVAVNC 283 M+++ + + ++ ++I GE+GTGKEL A+A+H + R+ PFVA+N Sbjct: 145 AMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHD-----YGKRRNG---PFVAINM 196 Query: 284 GAIAESLLEAELFGYEEGAFTGSRRGGRAGLFEIAHGGTLFLDEIGEMPLPLQTRLLRVL 343 AI L+E+ELFG+E+GAFTG++ G FE A GGTLFLDEIG+MP+ QTRLLRVL Sbjct: 197 AAIPRDLIESELFGHEKGAFTGAQTR-STGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVL 255 Query: 344 EEKEVTRVGGHQPVPVDVRVISATHCNLEEDMQQGRFRRDLFYRLSILRLQLPPLRERVA 403 ++ E T VGG P+ DVR+++AT+ +L++ + QG FR DL+YRL+++ L+LPPLR+R Sbjct: 256 QQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAE 315 Query: 404 DILPLAESFLKVSLAALSAPFSAALRQGLQASETVLLHYDWPGNIRELRNMMERLALFLS 463 DI L F++ ++ L+ + + WPGN+REL N++ RL Sbjct: 316 DIPDLVRHFVQ-QAEKEGLDVKRFDQEALEL----MKAHPWPGNVRELENLVRRLTALYP 370 Query: 464 VEP-TPDLTPQFMQLLLPELARESAKTPAPRLLTP------------------------- 497 + T ++ ++ +P+ E A + L Sbjct: 371 QDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYD 430 Query: 498 -----------QQALEKFNGDKTAAANYLGISRTTFWRRLK 527 AL G++ AA+ LG++R T ++++ Sbjct: 431 RVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIR 471
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 29.8 bits (67), Expect = 0.022 Identities = 11/33 (33%), Positives = 19/33 (57%), Gaps = 1/33 (3%) Query: 65 LIHGKLPTRDE-LAAYKTKLKALRGLPANVRTV 96 + +LPT +E AYK ++ + G P +RT+ Sbjct: 303 MDRDQLPTEEEQFEAYKEVVQRMDGKPVVIRTL 335
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 30.3 bits (68), Expect = 0.006 Identities = 24/129 (18%), Positives = 53/129 (41%), Gaps = 22/129 (17%) Query: 80 FYANFN----LTIVDDYTVTIGDNVLIAPNVTLSVTGHPVHHELRKNGEMYSFPITIGNN 135 F A+F ++ + + V+I P+V ++T +++ + Y F +++ + Sbjct: 30 FSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTIT--VRSYDMLNEEQYYQFFLSV-LD 86 Query: 136 VWIGSHVVINPGVTI---------------GDNSVIGAGSIVTKDIPPNVVAAGVPCRVI 180 V+ + + +N GV D + +VT+ +P VAA ++ Sbjct: 87 VYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIGDEVVTRVVPLTNVAARDLAPLL 146 Query: 181 REINDRDKH 189 R++ND Sbjct: 147 RQLNDNAGV 155
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 35.6 bits (82), Expect = 3e-04 Identities = 44/192 (22%), Positives = 72/192 (37%), Gaps = 22/192 (11%) Query: 4 LKNTNFWMFGLFFFFYFFI-MGAYFPFFPIWLHDINHISK--SDTGIIFAAISLFSLLFQ 60 +K + L + +G P P L D+ H + + GI+ A +L Sbjct: 1 MKPNRPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACA 60 Query: 61 PLFGLLSDKLGLRKYLLWIITGMLVMFAPFFIFIFGPLLQYNILVGSIVGGIYLGFCFNA 120 P+ G LSD+ G R LL + + I P L + + +G IV GI A Sbjct: 61 PVLGALSDRFGRRPVLL---VSLAGAAVDYAIMATAPFL-WVLYIGRIVAGIT-----GA 111 Query: 121 GAPAVEAFIEKVSRRSNFEFGRARMFG----CVGWALCAS--IVGIMFTINNQFVFWLGS 174 A+I ++ RAR FG C G+ + A + G+M + F+ + Sbjct: 112 TGAVAGAYIADITDGDE----RARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAA 167 Query: 175 GCALILAVLLFF 186 + + F Sbjct: 168 ALNGLNFLTGCF 179
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 33.3 bits (76), Expect = 0.003 Identities = 21/96 (21%), Positives = 42/96 (43%), Gaps = 4/96 (4%) Query: 92 AAVGVVQQLRTDVMDAA--LRQPLSEFDTQ-PVGQVISRVTNDTEVIRDLYVTVVATVLR 148 A +G+ + +D A ++ L+E P G + + T ++ VV T+ Sbjct: 287 AGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFE 346 Query: 149 SAALVGAMLVAMFSLDWRMALVAIMIFPVVLVVMVI 184 + LV +++ +F + R L+ + PVVL+ Sbjct: 347 AIMLV-FLVMYLFLQNMRATLIPTIAVPVVLLGTFA 381
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1369 bits (3546), Expect = 0.0 Identities = 802/1033 (77%), Positives = 915/1033 (88%), Gaps = 1/1033 (0%) Query: 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDT 60 M NFFI RPIFAWV+AII+M+AG LAIL+LPVAQYPTIAPPAV++SA+YPGADA+TVQDT Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQ 120 VTQVIEQNMNGIDNLMYMSS SDS G+V ITLTF+SGTD DIAQVQVQNKLQLA PLLPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGS 180 EVQQQG+SVEKSSSS+LMV G ++ + TQ+DISDYVA+N+KD +SR +GVGDVQLFG+ Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240 QYAMRIW++ + LNK++LTPVDVI +K QN Q+AAGQLGGTP + GQQLNASIIAQTR Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 TSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANAL 300 + EEFGK+ L+VN DGS V L+DVA++ELGGENY++IA NG+PA+GLGIKLATGANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 DTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQ 360 DTA AI+A+LA+++PFFP G+K++YPYDTTPFV++SIHEVVKTL EAI+LVFLVMYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 N RATLIPTIAVPVVLLGTFA+LAAFG+SINTLTMFGMVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 AEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480 E+ LPPKEAT KSM QIQGALVGIAMVLSAVF+PMAFFGGSTGAIYRQFSITIVSAMAL Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGR 540 SVLVALILTPALCAT+LKP++ H E K GFFGWFN F+ S +HYT+SVG IL STGR Sbjct: 481 SVLVALILTPALCATLLKPVSAE-HHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 541 YLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLT 600 YL++Y +IV GM LF+RLPSSFLP+EDQGVF+TM+QLPAGATQERTQKVL++VT YYL Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 601 KEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKD 660 EK NVESVF VNGF F+G+ QN G+AFVSLK W +R G+EN EA+ RA +I+D Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRD 659 Query: 661 AMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNG 720 V FN+PAIVELGTATGFDFELIDQAGLGH+ LTQARNQLL AA+HP L SVRPNG Sbjct: 660 GFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNG 719 Query: 721 LEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYR 780 LEDT QFK+++DQEKAQALGVS++DIN T+ A GG+YVNDFIDRGRVKK+YV ++AK+R Sbjct: 720 LEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFR 779 Query: 781 MLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEA 840 MLP+D+ YVR+A+G+MVPFSAF++S W YGSPRLERYNGLPSMEI G+AAPG S+G+A Sbjct: 780 MLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDA 839 Query: 841 MELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFS 900 M LME LASKLP G+GYDWTGMSYQERLSGNQAP+L AIS +VVFLCLAALYESWSIP S Sbjct: 840 MALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVS 899 Query: 901 VMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL 960 VMLVVPLG++G LLAAT NDVYF VGLLTTIGLSAKNAILIVEFAKDLM+KEGKG+ Sbjct: 900 VMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGV 959 Query: 961 IEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIF 1020 +EATL AVRMRLRPILMTSLAFILGV+PL IS GAGSGAQNAVG GVMGGMV+AT+LAIF Sbjct: 960 VEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIF 1019 Query: 1021 FVPVFFVVVRRRF 1033 FVPVFFVV+RR F Sbjct: 1020 FVPVFFVVIRRCF 1032
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 44.0 bits (104), Expect = 6e-07 Identities = 33/212 (15%), Positives = 71/212 (33%), Gaps = 23/212 (10%) Query: 100 TYQATYDSAKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTA 159 + Y A +L + + Q+ Q +++ ++ L +Q + Sbjct: 256 EQENKYVEAVNELR--VYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGL 313 Query: 160 AKAAVETARINLAYTKVTSPISGRIGKSNV-TEGALVQNGQATALATVQQLDPIYVDVTQ 218 + + + +P+S ++ + V TEG +V + T + V + D + V Sbjct: 314 LTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAE-TLMVIVPEDDTLEVTALV 372 Query: 219 SSNDFLRLKQELA----------NGTLKQENGKAKVSLITSDGIKFPQDGTLEFSDVTVD 268 + D + KV I D I+ + G + ++++ Sbjct: 373 QNKDIGFINVGQNAIIKVEAFPYTRYGYLV---GKVKNINLDAIEDQRLGLVFNVIISIE 429 Query: 269 QTTGSITLRAIFPNPDHTLLPGMFVRARLEEG 300 + S + I L GM V A ++ G Sbjct: 430 ENCLSTGNKNIP------LSSGMAVTAEIKTG 455 Score = 34.4 bits (79), Expect = 8e-04 Identities = 24/125 (19%), Positives = 43/125 (34%), Gaps = 13/125 (10%) Query: 49 PLQITTELPGR-TSAYRIAEVRPQVSGIILKRNFKEGSDIEAGVSLYQIDPATYQATYDS 107 ++I G+ T + R E++P + I+ + KEG + G L ++ +A Sbjct: 79 QVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEA---- 134 Query: 108 AKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTAAKAAVETA 167 D K Q++ A+L RYQ L E ++ Sbjct: 135 ---DTLKTQSSLLQARLEQTRYQILS-----RSIELNKLPELKLPDEPYFQNVSEEEVLR 186 Query: 168 RINLA 172 +L Sbjct: 187 LTSLI 191
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 201 bits (511), Expect = 2e-67 Identities = 189/192 (98%), Positives = 189/192 (98%) Query: 36 FLTAGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPG 95 F GVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPG Sbjct: 24 FSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPG 83 Query: 96 DPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRNLCLESYDRIEQ 155 DPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRNLCLESYDRIEQ Sbjct: 84 DPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRNLCLESYDRIEQ 143 Query: 156 TLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLKKEARDYVAILLEMYL 215 TLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLKKEARDYVAILLEMYL Sbjct: 144 TLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLKKEARDYVAILLEMYL 203 Query: 216 LCPTLRNPATNE 227 LCPTLRNPATNE Sbjct: 204 LCPTLRNPATNE 215
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.7 bits (72), Expect = 0.017 Identities = 19/125 (15%), Positives = 40/125 (32%), Gaps = 6/125 (4%) Query: 28 QNTAFARASSNGDLPTKADLQAQLDSLNKQKDLSAQDKLVQQDLTDTLATLDKIDRIKEE 87 N RA L + + L L+ + A L++ ++ E Sbjct: 207 LNLDKKRAERLTVLARINRYENLSRVEKSR--LDDFSSLLHKQAIAKHAVLEQENKYVEA 264 Query: 88 TVQLRQKVAEAPEKMRQATAALTALSDVDND--EETRKIL--STLSLRQLETRVAQALDD 143 +LR ++ + + +A V E L +T ++ L +A+ + Sbjct: 265 VNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEER 324 Query: 144 LQNAQ 148 Q + Sbjct: 325 QQASV 329
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 39.7 bits (92), Expect = 4e-05 Identities = 40/251 (15%), Positives = 77/251 (30%), Gaps = 31/251 (12%) Query: 404 PLPETTSQVLAARQQLQRVQGATKAKKSEPAA----ATRARPVNNAALERLASVTDRVQA 459 P E +Q + + + P+ AR + A + A T Sbjct: 983 PEVEKRNQTVDTTN----ITTPNNIQADVPSVPSNNEEIARV-DEAPVPPPAPATPSETT 1037 Query: 460 RPVPSALEKAPAKKEAYRWKATTPVMQQKE--------VVATPKALKKA---LEHEKTPE 508 V ++ E AT Q +E V A + + A E ++T Sbjct: 1038 ETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQT 1097 Query: 509 LAAKLAA---------EAIERDPWAAQVSQLSLPKLVEQVALNAWKE-ESDNAVCLHLRS 558 K A E+ +V+ PK + + E +N ++++ Sbjct: 1098 TETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKE 1157 Query: 559 SQRHLNNRGAQQKLAEALS-MLKGSTVELTIVEDDNPAVRTPLEWRQAIYEEKLAQARES 617 Q N ++ A+ S ++ E T V N V P A + + + Sbjct: 1158 PQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSN 1217 Query: 618 IIADNNIQTLR 628 + + +++R Sbjct: 1218 KPKNRHRRSVR 1228
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 27.8 bits (62), Expect = 0.047 Identities = 11/43 (25%), Positives = 18/43 (41%) Query: 38 GQLAAVAIVTCDGNVYSAGDSDYRFALESISKVCTLALALEDV 80 G++ + + G +A +D RF + S KV L V Sbjct: 38 GRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARV 80
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 77.8 bits (191), Expect = 4e-19 Identities = 49/212 (23%), Positives = 81/212 (38%), Gaps = 7/212 (3%) Query: 3 KSVLITGCSSGIGLESALELKRQGFHVLAGCRKPDDVERMNS----MGFT--GVLIDLDS 56 K ITG + GIG A L QG H+ A P+ +E++ S D+ Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 57 PESVDRAADEVIALTDNCLYGIFNNAGFGMYGPLSTISRAQMEQQFSANFFGAHQLTMRL 116 ++D + + + N AG G + ++S + E FS N G + + Sbjct: 69 SAAIDEITARIEREMGP-IDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 117 LPAMLPHGEGRIVMTSSVMGLISTPGRGAYAASKYALEAWSDALRMELRHSGIKVSLIEP 176 M+ G IV S + AYA+SK A ++ L +EL I+ +++ P Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 177 GPIRTRFTDNVNQTQSDKPVENPGIAARFTLG 208 G T ++ ++ G F G Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLETFKTG 219
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.014 Identities = 12/20 (60%), Positives = 13/20 (65%) Query: 41 LVGESGSGKSTLLAILAGLD 60 L G G GKSTL+ L GLD Sbjct: 601 LEGTGGIGKSTLINTLVGLD 620
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 55.1 bits (133), Expect = 3e-10 Identities = 39/163 (23%), Positives = 59/163 (36%), Gaps = 32/163 (19%) Query: 4 DLIIKNGTVILENEARVVDIAVKGGKIAAIG-------QD-----LGDAKEVMDASGLVV 51 D +I N ++ DI +K G+IAAIG Q +G EV+ G +V Sbjct: 69 DTVITNALILDHWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIV 128 Query: 52 SPGMVDAHTHISEPGRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRAS------- 104 + G +D+H H P + A G+T M+ PA A+ Sbjct: 129 TAGGMDSHIHFICPQQIE---------EALMSGLTCMLGGGTG--PAHGTLATTCTPGPW 177 Query: 105 -IELKFDAAKGKLTIDAAQLGGLVSYNIDRLHELDEVGVVGFK 146 I +AA ++ A G + L E+ G K Sbjct: 178 HIARMIEAADA-FPMNLAFAGKGNASLPGALVEMVLGGATSLK 219
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 386 bits (992), Expect = e-138 Identities = 126/310 (40%), Positives = 176/310 (56%), Gaps = 16/310 (5%) Query: 2 KTLVVALGGNALLQRGEALTAENQYRNIASAVPALARL-ARSYRLAIVHGNGPQVGLLAL 60 K +V+ALGGNAL QRG+ + E N+ +A + AR Y + I HGNGPQVG L L Sbjct: 3 KRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSLLL 62 Query: 61 QNLAWKE---VEPYPLDVLVAESQGMIGYMLAQSLSAQPQM----PPVTTVLTRIEVSPD 113 A + + P+DV A SQG IGYM+ Q+L + + V T++T+ V + Sbjct: 63 HMDAGQATYGIPAQPMDVAGAMSQGWIGYMIQQALKNELRKRGMEKKVVTIITQTIVDKN 122 Query: 114 DPAFLQPEKFIGPVYQPEEQEALEAAYGWQMKRD-GKYLRRVVASPQPRKILDSEAIELL 172 DPAF P K +GP Y E + L GW +K D G+ RRVV SP P+ +++E I+ L Sbjct: 123 DPAFQNPTKPVGPFYDEETAKRLAREKGWIVKEDSGRGWRRVVPSPDPKGHVEAETIKKL 182 Query: 173 LKEGHVVICSGGGGVPVTDDG---AGSEAVIDKDLAAALLAEQINADGLVILTDADAVYE 229 ++ G +VI SGGGGVPV + G EAVIDKDLA LAE++NAD +ILTD + Sbjct: 183 VERGVIVIASGGGGVPVILEDGEIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVNGAAL 242 Query: 230 NWGTPQQRAIRHATPDELAPFAKAD----GSMGPKVTAVSGYVRSRGKPAWIGALSRIEE 285 +GT +++ +R +EL + + GSMGPKV A ++ G+ A I L + E Sbjct: 243 YYGTEKEQWLREVKVEELRKYYEEGHFKAGSMGPKVLAAIRFIEWGGERAIIAHLEKAVE 302 Query: 286 TLAGEAGTCI 295 L G+ GT + Sbjct: 303 ALEGKTGTQV 312
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.4 bits (66), Expect = 0.029 Identities = 16/150 (10%), Positives = 44/150 (29%), Gaps = 8/150 (5%) Query: 299 RSQLNYSEENLKQARAALERLYTALRGTDKTVAPAGGEAFEARFIEAMDDDFNTP----- 353 + ++ +L QAR R R + P E F +++ Sbjct: 133 EADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIK 192 Query: 354 EAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLGLLEQEPEAFLQSGAQADDSEV 413 E +S + + + A + + + + + + + + F + Sbjct: 193 EQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSS---LLHKQAI 249 Query: 414 AEIEALIQQRLDARKAKDWAAADAARDRLN 443 A+ L Q+ + + +++ Sbjct: 250 AKHAVLEQENKYVEAVNELRVYKSQLEQIE 279
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 818 bits (2115), Expect = 0.0 Identities = 402/855 (47%), Positives = 570/855 (66%), Gaps = 20/855 (2%) Query: 20 ICYSSLAILPSFLSYAESYFNPAFLLENGTSVADLSRFERGNHQPAGVYRVDLWRNDEFI 79 + A + LS AE YFNP FL ++ +VADLSRFE G P G YRVD++ N+ ++ Sbjct: 31 FVACAFA-AQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGYM 89 Query: 80 GSQDIVFESTTENTGDKSGGLMPCFNQVLLERIGLNSSAFPELAQQQNNKCINLLKAVPD 139 ++D+ F NTGD G++PC + L +GLN+++ + ++ C+ L + D Sbjct: 90 ATRDVTF-----NTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLTSMIHD 144 Query: 140 ATINFDFAAMRLNITIPQIALLSSAHGYIPPEEWDEGIPALLLNYNFTGN----RGNGND 195 AT D RLN+TIPQ + + A GYIPPE WD GI A LLNYNF+GN R GN Sbjct: 145 ATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNS 204 Query: 196 SYFFSEL-SGINIGPWRLRNNGSWNYFRGNG--YHSEQWNNIGTWVQRAIIPLKSELVMG 252 Y + L SG+NIG WRLR+N +W+Y + +W +I TW++R IIPL+S L +G Sbjct: 205 HYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTLG 264 Query: 253 DGNTGSDIFDGVGFRGVRLYSSDNMYPDSQQGFAPTVRGIARTAAQLTIRQNGFIIYQSY 312 DG T DIFDG+ FRG +L S DNM PDSQ+GFAP + GIAR AQ+TI+QNG+ IY S Sbjct: 265 DGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNST 324 Query: 313 VSPGAFEITDLHPTSSNGDLDVTIDERDGNQQNYTIPYSTVPILQREGRFKFDLTAGDFR 372 V PG F I D++ ++GDL VTI E DG+ Q +T+PYS+VP+LQREG ++ +TAG++R Sbjct: 325 VPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYR 384 Query: 373 SGNSQQSSPFFFQGTALGGLPQEFTAYGGTQLSANYTAFLLGLGRNLGNWGAVSLDVTHA 432 SGN+QQ P FFQ T L GLP +T YGGTQL+ Y AF G+G+N+G GA+S+D+T A Sbjct: 385 SGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQA 444 Query: 433 RSQLADASRHEGDSIRFLYAKSMNTFGTNFQLMGYRYSTQGFYTLDDVAYRRMEGY-EYD 491 S L D S+H+G S+RFLY KS+N GTN QL+GYRYST G++ D Y RM GY Sbjct: 445 NSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIET 504 Query: 492 YDGEHRDEPIIVNYHNLRFSRKDRLQLNVSQSLNDFGSLYISGTHQKYWNTSDSDTWYQV 551 DG + +P +Y+NL ++++ +LQL V+Q L +LY+SG+HQ YW TS+ D +Q Sbjct: 505 QDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSNVDEQFQA 564 Query: 552 GYTSSWVGISYSLSFSWNESVGIPDNERIVGLNVSVPFNVLTKRRYTRENALDRAYASFN 611 G +++ I+++LS+S ++ ++++ LNV++PF+ R ++ A AS++ Sbjct: 565 GLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWL--RSDSKSQWRHASASYS 622 Query: 612 ANRNSNGQNSWLAGVGGTLLEGHNLSYHVSQG----DTSNNGYTGSATANWQAAYGTLGG 667 + + NG+ + LAGV GTLLE +NLSY V G N+G TG AT N++ YG Sbjct: 623 MSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANI 682 Query: 668 GYNYDRDQHDVNWQLSGGVVGHENGITLSQPLGDTNVLIKAPGAGGVRIENQTGILTDWR 727 GY++ D + + +SGGV+ H NG+TL QPL DT VL+KAPGA ++ENQTG+ TDWR Sbjct: 683 GYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTDWR 742 Query: 728 GYAVMLYATVYRYNRIALDTNTMGNSIDVEKNISSVVPTQGALVRANFDTRIGVRALITV 787 GYAV+ YAT YR NR+ALDTNT+ +++D++ +++VVPT+GA+VRA F R+G++ L+T+ Sbjct: 743 GYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKLLMTL 802 Query: 788 TQGGKPVPFGSLVRENSTGITSMVGDDGQVYLSGAPLSGELLVQWGDGANSRCIAHYVLP 847 T KP+PFG++V S+ + +V D+GQVYLSG PL+G++ V+WG+ N+ C+A+Y LP Sbjct: 803 THNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCVANYQLP 862 Query: 848 KQSLQQAVTVISAVC 862 +S QQ +T +SA C Sbjct: 863 PESQQQLLTQLSAEC 877
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 34.8 bits (80), Expect = 6e-04 Identities = 81/393 (20%), Positives = 144/393 (36%), Gaps = 38/393 (9%) Query: 27 FISIVSLGLLGVAVPVQIQMMTHSTWQV---GLSVTLTGGAMFVGLMVGGVLADRYERKK 83 + V +GL+ +P ++ + HS G+ + L F V G L+DR+ R+ Sbjct: 15 ALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRP 74 Query: 84 VILLARGTCGIGFIGLCLNALL--PEPSLLAIYLLGLWDGFFASLGVTALLAATPALVGR 141 V+L + G ++ + P L +Y+ + G + G A A + Sbjct: 75 VLL-------VSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVA-GAYIADITDG 126 Query: 142 ENLMQAGAITMLTVRLGSVISPMIGGLLLATGGVAWNYGLAAAGTFITLLPLLSLPALPP 201 + + G V P++GGL+ GG + + AA L L LP Sbjct: 127 DERARHFGFMSACFGFGMVAGPVLGGLM---GGFSPHAPFFAAAALNGLNFLTGCFLLPE 183 Query: 202 PPQPREHPLK----SLLAGFRFLLASPLVGGIALLGGLLTMAS----AVRVLYPALADNW 253 + PL+ + LA FR+ +V + + ++ + A+ V++ D + Sbjct: 184 SHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFG--EDRF 241 Query: 254 QMSAAQIGFLYAAIP-LGAAIGALTSGKLAHSARPGLLMLLSTLGS---FLAIGLFGLMP 309 A IG AA L + A+ +G +A ++L + ++ + Sbjct: 242 HWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGW 301 Query: 310 MWILGVVCLALFGWLSAVSSLLQYTMLQTQTPEAMLGRINGLWTAQNVTGDAIGAALLGG 369 M +V LA G ML Q E G++ G A +G L Sbjct: 302 MAFPIMVLLASGGIGMPALQ----AMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTA 357 Query: 370 LGAMMTPVASASASGFGLLIIGVLLLLVLVELR 402 + A + + +G+ + L LL L LR Sbjct: 358 IYA----ASITTWNGWAWIAGAALYLLCLPALR 386
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 62.7 bits (152), Expect = 2e-13 Identities = 60/280 (21%), Positives = 100/280 (35%), Gaps = 35/280 (12%) Query: 40 HTLESQPQRIVSTSVTLTGSLLAIDAPVIASGATTPNNRVADDQGFLRQWSKVAKERKLQ 99 H P RIV+ LLA+ VAD + R W E L Sbjct: 29 HAAAIDPNRIVALEWLPVELLLALGIVPYG---------VADTINY-RLW---VSEPPLP 75 Query: 100 RLYIG-----EPSAEAVAAQMPDLILISATGGDSALALYDQLSTIAPTLIINYDDKS--- 151 I EP+ E + P ++ SA G S + L+ IAP N+ D Sbjct: 76 DSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPS----PEMLARIAPGRGFNFSDGKQPL 131 Query: 152 --WQSLLTQLGEITGHEKQAAERIAQFDKQLAAAKEQIKLPPQPVTAIVYTAAAHSANLW 209 + LT++ ++ + A +AQ++ + + K + + ++ Sbjct: 132 AMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVF 191 Query: 210 TPESAQGQMLEQLGFTLAKLPAGLNASQSQGKRHDIIQLGGENLAAGLNGESLFLFAGDQ 269 P S ++L++ G NA Q + + + LAA + + L + Sbjct: 192 GPNSLFQEILDEYGIP--------NAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNS 243 Query: 270 KDADAIYANPLLAHLPAVQNKQVYALGTETFRLDYYSAMQ 309 KD DA+ A PL +P V+ + + F SAM Sbjct: 244 KDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMH 283
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 440 bits (1134), Expect = e-159 Identities = 145/299 (48%), Positives = 194/299 (64%), Gaps = 18/299 (6%) Query: 1 MAIPKLQAYALPESHDIPQNKVDWAFEPQRAALLIHDMQDYFVSFWGENCPMMEQVIANI 60 MAIP +Q Y +P + D+PQNKV W +P RA LLIHDMQ+YFV + + ++ ANI Sbjct: 1 MAIPAIQPYQMPTASDMPQNKVSWVPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANI 60 Query: 61 AALRDYCKQHNIPVYYTAQPKEQSDEDRALLNDMWGPGLTRSPEQQKVVDRLTPDADDTV 120 L++ C Q IPV YTAQP Q+ +DRALL D WGPGL P ++K++ L P+ DD V Sbjct: 61 RKLKNQCVQLGIPVVYTAQPGSQNPDDRALLTDFWGPGLNSGPYEEKIITELAPEDDDLV 120 Query: 121 LVKWRYSAFHRSPLEQMLKESGRNQLIITGVYAHIGCMTTATDAFMRDIKPFMVADALAD 180 L KWRYSAF R+ L +M+++ GR+QLIITG+YAHIGC+ TA +AFM DIK F V DA+AD Sbjct: 121 LTKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVAD 180 Query: 181 LSRDEHLMSLKYVAGRSGRVVMTEELL------PAPIPASKA-----------ALREVIL 223 S ++H M+L+Y AGR VMT+ LL PA + + A +R+ I Sbjct: 181 FSLEKHQMALEYAAGRCAFTVMTDSLLDQLQNAPADVQKTSANTGKKNVFTCENIRKQIA 240 Query: 224 PLLDESDEPFDDD-NLIDYGLDSVRMMALAARWRKVHGDIDFVMLAKNPTIDAWWKLLS 281 LL E+ E D +L+D GLDSVR+M L +WR+ ++ FV LA+ PTI+ W KLL+ Sbjct: 241 ELLQETPEDITDQEDLLDRGLDSVRIMTLVEQWRREGAEVTFVELAERPTIEEWQKLLT 299
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 364 bits (935), Expect = e-131 Identities = 110/258 (42%), Positives = 149/258 (57%), Gaps = 20/258 (7%) Query: 5 GKNVWVTGAGKGIGYATALAFVEAGAKVTGFD---------------QAFTQEQYPFATE 49 GK ++TGA +GIG A A GA + D +A E +P Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP---- 63 Query: 50 VMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109 DV D+A + ++ R+ E +D LVN AG+LR G LS E+W+ TF+VN G FN Sbjct: 64 -ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 110 LFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 + +R G+IVTV S+ A PR M+AY +SKAA +GLELA +RC Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 170 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 229 N+VSPGST+TDMQ +LW ++ EQ I+G E FK GIPL K+A+P +IA+ +LFL S Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 230 ASHITLQDIVVDGGSTLG 247 A HIT+ ++ VDGG+TLG Sbjct: 243 AGHITMHNLCVDGGATLG 260
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 92.2 bits (229), Expect = 7e-24 Identities = 35/125 (28%), Positives = 58/125 (46%), Gaps = 1/125 (0%) Query: 2 TNVLIVEDEQAIRRFLRTALEGDGMRVFEAETLQRGLLEAATRKPDLIILDLGLPDGDGI 61 +L+ +D+ AIR L AL G V A DL++ D+ +PD + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 EFIRDLRQWSA-VPVIVLSARSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHS 120 + + +++ +PV+V+SA++ I A + GA DYL KPF + EL + AL Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 121 ATTAP 125 + Sbjct: 124 RRPSK 128
>PF06580#Sensor histidine kinase Length = 349 Score = 31.8 bits (72), Expect = 0.012 Identities = 10/48 (20%), Positives = 21/48 (43%), Gaps = 4/48 (8%) Query: 785 LLENAVKYAGAQAE----IGIDAHVEGENLQLDVWDNGPGLPPGQEQT 828 L+EN +K+ AQ I + + + L+V + G +++ Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKES 310
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 602 bits (1553), Expect = 0.0 Identities = 235/861 (27%), Positives = 379/861 (44%), Gaps = 63/861 (7%) Query: 5 RLSFVSCLVMAMPCAMA-VEFNLNVLDKSMRDRIDISLLKEKGVIAPGEYFVSVAVNNNK 63 RL P + A + FN L + D+S + + PG Y V + +NN Sbjct: 29 RLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGY 88 Query: 64 ISNGQ-KINWQKKGDKTIPCINDSLVDKFGLKPDIRQSLPQI--DRCIDFSSR-PEMLFN 119 ++ N +PC+ + + GL + + D C+ +S + Sbjct: 89 MATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLTSMIHDATAQ 148 Query: 120 FDQANQQLNISIPQAWLAWHSENWAPPSTWKEGVAGVLMDYNLFASSYRPQDGSSSTNLN 179 D Q+LN++IPQA+++ + + PP W G+ L++YN +S + + G +S Sbjct: 149 LDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNSHYAY 208 Query: 180 AYGTAGINAGAWRLRSDYQLNKTDSEDNHDQSGGI--SRTYLFRPLPQLGSKLTLGETDF 237 +G+N GAWRLR + + S+ + T+L R + L S+LTLG+ Sbjct: 209 LNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTLGDGYT 268 Query: 238 SSNIFDGFSYTGAALASDDRMLPWELRGYAPQISGIAQTNATVTISQSGRVIYQKKVPPG 297 +IFDG ++ GA LASDD MLP RG+AP I GIA+ A VTI Q+G IY VPPG Sbjct: 269 QGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPPG 328 Query: 298 PFIIDDLNQ-SVQGTLDVKVTEEDGRVNNFQVSAASTPFLTRQGQVRYKLAAGQPRPSMS 356 PF I+D+ G L V + E DG F V +S P L R+G RY + AG+ R + Sbjct: 329 PFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYRSG-N 387 Query: 357 HQTENETFFSNEVSWGMLSNTSLYGGLLISDDDYHSAAMGIGQNMLWLGALSFDVTWASS 416 Q E FF + + G+ + ++YGG ++ D Y + GIG+NM LGALS D+T A+S Sbjct: 388 AQQEKPRFFQSTLLHGLPAGWTIYGGTQLA-DRYRAFNFGIGKNMGALGALSVDMTQANS 446 Query: 417 HFDTQQDERGLSYRFNYSKQVDATNSTISLAAYRFSDRHFHSYANYLDHKYND------- 469 G S RF Y+K ++ + + I L YR+S + ++A+ + N Sbjct: 447 TLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQD 506 Query: 470 -------------SDAQDEKQTISLSVGQPITPLNLNLYANLLHQTWWNADASTTANITA 516 + A +++ + L+V Q + LY + HQT+W A Sbjct: 507 GVIQVKPKFTDYYNLAYNKRGKLQLTVTQQL-GRTSTLYLSGSHQTYWGTSNVDE-QFQA 564 Query: 517 GFNVDIGDWRDISISTSFNTTHYE-DKDRDNQIYLSISLPFGNGGR-----------VGY 564 G N + DI+ + S++ T K RD + L++++PF + R Y Sbjct: 565 GLNT---AFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHASASY 621 Query: 565 DMQNSSHS-TIHRMSWNDTLDERN--SWGMSAGL-QSDRPDNGAQVSGNYQHLSSAGEWD 620 M + + + TL E N S+ + G ++G+ + G + Sbjct: 622 SMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNAN 681 Query: 621 ISGTYAASDYSSVSSSWSGSFTATQYGAAFHRRSSTNEPRLMVSTDGVADIPVQGNLDY- 679 I ++ + D + SG A G + N+ ++V G D V+ Sbjct: 682 IGYSH-SDDIKQLYYGVSGGVLAHANGVTLGQP--LNDTVVLVKAPGAKDAKVENQTGVR 738 Query: 680 TNHFGIAVVPLISSYQPSTVAVNMNDLPDGVTVAENVIKETWIEGAIGYKSLASRSGKDV 739 T+ G AV+P + Y+ + VA++ N L D V + V GAI +R G + Sbjct: 739 TDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKL 798 Query: 740 NVIIRNASGQFPPLGADIRQDDSGISVGMVGEEGHAWLSGVAENQLFTVVWGE---QSCI 796 + + + + P GA + +S S G+V + G +LSG+ V WGE C+ Sbjct: 799 LMTLT-HNNKPLPFGAMV-TSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCV 856 Query: 797 IH--LPERLEDTT-KRLILPC 814 + LP + +L C Sbjct: 857 ANYQLPPESQQQLLTQLSAEC 877
>FIMBRIALPAPE#Escherichia coli: P pili tip fibrillum papE protein signature. Length = 173 Score = 34.6 bits (79), Expect = 9e-05 Identities = 39/179 (21%), Positives = 78/179 (43%), Gaps = 26/179 (14%) Query: 14 SLLFTAPVYAADEGSGEIHFKGEVIEAPCEIHPEDID-KNIDLGQVTTTHINREHHSNKV 72 ++L + V+AAD + FKG++I C + +++ +I++ + + N++ + Sbjct: 15 AVLMSQHVHAADN----LTFKGKLIIPACTVQNAEVNWGDIEIQNLVQSGGNQKDFT--- 67 Query: 73 AVDIRLINCDLPASDNGSGMPVSKVGVTFDSTAKTTGATPLLSNTSAGEATGVGVRLMDK 132 ++ + P S + + VT S TG + L+ NTS G+ + L + Sbjct: 68 ------VDMNCPYS-------LGTMKVTITSNG-QTGNSILVPNTSTASGDGLLIYLYNS 113 Query: 133 NDGNI----VLGSAAPDLDLDASSSEQTLNFFAWMEQIDNAVDVTAGEVTANATYVLDY 187 N+ I LGS + ++ + + +A + N + AG +A AT V Y Sbjct: 114 NNSGIGNAVTLGSQVTPGKITGTAPARKITLYAKLGYKGNMQSLQAGTFSATATLVASY 172
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 30.6 bits (69), Expect = 0.006 Identities = 11/41 (26%), Positives = 23/41 (56%), Gaps = 1/41 (2%) Query: 14 VDDAPRMQDYTLEADEGRDM-MLLDALIQLKEKDPSLSFRR 53 +++ + T+E + + MLLDAL+++ + DP L + Sbjct: 339 IENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYV 379
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.8 bits (67), Expect = 0.020 Identities = 27/196 (13%), Positives = 56/196 (28%), Gaps = 12/196 (6%) Query: 48 EVPASADGILDAVLEDEGTTVTSRQILGRLREGNSAGKETSAKSE-EKASTPAQRQQASL 106 E+ + I+ ++ EG +V +L +L + +S +A R Q Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILS 157 Query: 107 EEQNNDAL----SPAIRRLLAEHNLDASAIKGTGVGGRLTRED----VEKHLAKAPAKES 158 + L P + + T ++ E +L K A+ Sbjct: 158 RSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERL 217 Query: 159 APAAAAPAAQPALAARSEKRVPMTRLRKRVA---ERLLEAKNSTAMLTTFNEVNMKPIMD 215 A + + + L + A +LE +N V + Sbjct: 218 TVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQ 277 Query: 216 LRKQYGEAFEKRHGIR 231 + + A E+ + Sbjct: 278 IESEILSAKEEYQLVT 293
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 60.1 bits (145), Expect = 9e-12 Identities = 34/199 (17%), Positives = 69/199 (34%), Gaps = 8/199 (4%) Query: 99 EQERLKQLEKERLAAQEQKKQAEEAAKQAELKQKQAEEAAAKAAADAKAKAEADAKAAEE 158 E E+ Q QA+ + E A A ++ E Sbjct: 984 EVEKRNQTVDTTNITTPNNIQADVPSVP----SNNEEIARVDEAPVPPPAPATPSETTET 1039 Query: 159 AAK--KAAADAKKKAEAEAAKAAAEAQKKAEAAAAALKKKAEAAEAA--AAEARKKAATE 214 A+ K + +K E +A + A+ ++ A+ A + +K + E A +E ++ TE Sbjct: 1040 VAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTE 1099 Query: 215 AAEKAKAEAEKKAAAEKAAADKKAAAEKAAADKKAAEKAAAEKAAADKKAAAEKAAADKK 274 E A E E+KA E + + K+ + +A ++ + + Sbjct: 1100 TKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQ 1159 Query: 275 AAAAKAAAEKAAAAKAAAE 293 + A + A + ++ Sbjct: 1160 SQTNTTADTEQPAKETSSN 1178 Score = 57.0 bits (137), Expect = 9e-11 Identities = 30/236 (12%), Positives = 85/236 (36%), Gaps = 11/236 (4%) Query: 68 QSQESSAKRSDEQRKMKEQQAAEELREKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQA 127 Q+ S ++E+ ++ +E ++ + +K E+ A + Sbjct: 1004 QADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKN--EQDATET 1061 Query: 128 ELKQKQ-AEEAAAKAAAD------AKAKAEADAKAAEEAAKKAAADAKKKAEAEAAKAAA 180 + ++ A+EA + A+ A++ +E E + A + ++KA+ E K Sbjct: 1062 TAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQE 1121 Query: 181 EAQKKAEAAAAALKKKAEAAEAAAAEARKKAATEAAEKAKAEAEKKAAAEKAAADKKAAA 240 + ++ + ++++E + A AR+ T ++ +++ A E+ A + + Sbjct: 1122 VPKVTSQVSPK--QEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNV 1179 Query: 241 EKAAADKKAAEKAAAEKAAADKKAAAEKAAADKKAAAAKAAAEKAAAAKAAAEADD 296 E+ + + + A ++ K + ++ + Sbjct: 1180 EQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVE 1235 Score = 56.2 bits (135), Expect = 2e-10 Identities = 28/228 (12%), Positives = 75/228 (32%), Gaps = 2/228 (0%) Query: 66 RMQSQESSAKRSDEQRKMKEQQAAEELREKQAAEQERLKQLEKERLAAQEQKKQAEEAAK 125 R ++E+ + + + Q+ E +E Q E + +EKE A E +K E Sbjct: 1066 REVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKV 1125 Query: 126 QAELKQKQAEEAAAKAAADAKAKAEADAKAAEEAAK--KAAADAKKKAEAEAAKAAAEAQ 183 +++ KQ + + A+ + + E ++ A + E + + Sbjct: 1126 TSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTE 1185 Query: 184 KKAEAAAAALKKKAEAAEAAAAEARKKAATEAAEKAKAEAEKKAAAEKAAADKKAAAEKA 243 ++ + E A + + + K + ++ ++ +++ Sbjct: 1186 STTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRS 1245 Query: 244 AADKKAAEKAAAEKAAADKKAAAEKAAADKKAAAAKAAAEKAAAAKAA 291 +D +A A+ A + A ++ ++ + Sbjct: 1246 TVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHISQLEMNNEGQ 1293 Score = 55.5 bits (133), Expect = 2e-10 Identities = 32/265 (12%), Positives = 86/265 (32%), Gaps = 14/265 (5%) Query: 51 DAVMVDSGAVVEQYKRMQSQESSAKRSDEQRKMKEQQAAE-ELREKQAAEQER------L 103 D V A + ++ ++K+ + + EQ A E + ++ A++ + Sbjct: 1021 DEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANT 1080 Query: 104 KQLEKERLAAQEQKKQAEEAAKQAELKQKQAEEAAAKAAADAKAKAEADAKAAEEAAKKA 163 + E + ++ ++ Q K+ +K+ KA + + E ++ + K+ Sbjct: 1081 QTNEVAQSGSETKETQ-TTETKETATVEKE-----EKAKVETEKTQEVPKVTSQVSPKQE 1134 Query: 164 AADA-KKKAEAEAAKAAAEAQKKAEAAAAALKKKAEAAEAAAAEARKKAATEAAEKAKAE 222 ++ + +AE K+ ++ + A+ ++ + Sbjct: 1135 QSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNS 1194 Query: 223 AEKKAAAEKAAADKKAAAEKAAADKKAAEKAAAEKAAADKKAAAEKAAADKKAAAAKAAA 282 + A + +++ K + + + + A + A + Sbjct: 1195 VVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTS 1254 Query: 283 EKAAAAKAAAEADDIFGELSSGKNA 307 A + A A F L+ GK Sbjct: 1255 TNTNAVLSDARAKAQFVALNVGKAV 1279
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 40.0 bits (93), Expect = 3e-06 Identities = 30/159 (18%), Positives = 53/159 (33%), Gaps = 20/159 (12%) Query: 7 RLDKNDAAVLLVDHQAGLLSLVRDIEP--DKFKNNVLALGDLAKYFNLPTILTT---SFE 61 D N A +L+ D Q + + N+ L + +P + T S Sbjct: 25 VPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCVQLGIPVVYTAQPGSQN 84 Query: 62 TGPNGPLV----PELKAQFPDTPYIAR----PGNI-------NAWDNEDFVKAVKATGKK 106 L P L + + I ++ +A+ + ++ ++ G+ Sbjct: 85 PDDRALLTDFWGPGLNSGPYEEKIITELAPEDDDLVLTKWRYSAFKRTNLLEMMRKEGRD 144 Query: 107 QLIIAGVVTEVCVAFPALSAIEEGFDVFVVTDASGTFNE 145 QLII G+ + A A E F V DA F+ Sbjct: 145 QLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVADFSL 183
>FIMBRIALPAPE#Escherichia coli: P pili tip fibrillum papE protein signature. Length = 173 Score = 28.5 bits (63), Expect = 0.012 Identities = 26/92 (28%), Positives = 37/92 (40%), Gaps = 14/92 (15%) Query: 6 LTAFITVVCATSSVMAADDNAITDGSVTFNGKVIAPACTLVAATKDSVVTLPDVSATKLQ 65 L + V + V AAD+ +TF GK+I PACT+ A V D+ L Sbjct: 9 LPVMLGAVLMSQHVHAADN-------LTFKGKLIIPACTVQNAE----VNWGDIEIQNLV 57 Query: 66 TNGQVS---GVQIDVPIELKDCDTTVTKNATF 94 +G V ++ P L T+T N Sbjct: 58 QSGGNQKDFTVDMNCPYSLGTMKVTITSNGQT 89
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 827 bits (2139), Expect = 0.0 Identities = 414/862 (48%), Positives = 569/862 (66%), Gaps = 18/862 (2%) Query: 15 GVPSFIGGLVVFVSAAFNAQAETWFDPAFFKDDPSMVADLSRFEKGQKITPGVYRVDIVL 74 G + F + A + AE +F+P F DDP VADLSRFE GQ++ PG YRVDI L Sbjct: 25 GFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYL 84 Query: 75 NQTIVDTRNVNFVEITPEKGIAACLTTESLDAMGVNTDAFPAFKQLDKQACVPLAEIIPD 134 N + TR+V F E+GI CLT L +MG+NT + L ACVPL +I D Sbjct: 85 NNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLTSMIHD 144 Query: 135 ASVTFNVNKLRLEISVPQIAIKSNARGYVPPERWDEGINALLLGYSFSGANSIHSSADSD 194 A+ +V + RL +++PQ + + ARGY+PPE WD GINA LL Y+FSG + + + Sbjct: 145 ATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNS 204 Query: 195 SGDSYFLNLNSGVNLGPWRLRNNSTWSR-----SSGQTAEWKNLSSYLQRAVIPLKGELT 249 +LNL SG+N+G WRLR+N+TWS SSG +W++++++L+R +IPL+ LT Sbjct: 205 --HYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLT 262 Query: 250 VGDDYTAGDFFDSVSFRGVQLASDDNMLPDSLKGFAPVVRGIAKSNAQITIKQNGYTIYQ 309 +GD YT GD FD ++FRG QLASDDNMLPDS +GFAPV+ GIA+ AQ+TIKQNGY IY Sbjct: 263 LGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYN 322 Query: 310 TYVSPGAFEISDLYSTSSSGDLLVEIKEADGSVNSYSVPFSSVPLLQRQGRIKYAVTLAK 369 + V PG F I+D+Y+ +SGDL V IKEADGS ++VP+SSVPLLQR+G +Y++T + Sbjct: 323 STVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGE 382 Query: 370 YRTNSNEQQESKFAQATLQWGGPWGTTWYGGGQYAEYYRAAMFGLGFNLGDFGAISFDAT 429 YR+ + +Q++ +F Q+TL G P G T YGG Q A+ YRA FG+G N+G GA+S D T Sbjct: 383 YRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMT 442 Query: 430 QAKSTLADQSEHKGQSYRFLYAKTLNHLGTNFQLMGYRYSTSGFYTLSDTMYKHMDGY-- 487 QA STL D S+H GQS RFLY K+LN GTN QL+GYRYSTSG++ +DT Y M+GY Sbjct: 443 QANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNI 502 Query: 488 EFNDGDDEDTPMWSRYYNLFYTKRGKLQVNISQQLGEYGSFYLSGSQQTYWHTDQQDRLL 547 E DG + P ++ YYNL Y KRGKLQ+ ++QQLG + YLSGS QTYW T D Sbjct: 503 ETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSNVDEQF 562 Query: 548 QFGYNTQIKDLSLGISWNYSKSRGQPDADQVFALNFSLPLNLLLPRSNDSYTRKKNYAWM 607 Q G NT +D++ +S++ +K+ Q DQ+ ALN ++P + L + S R +A Sbjct: 563 QAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWR---HASA 619 Query: 608 TSNTSIDNEGHTTQNLGLTETLLDDGNLSYSVQQGYNSEGKTANGS---ASMDYKGAFAD 664 + + S D G T G+ TLL+D NLSYSVQ GY G +GS A+++Y+G + + Sbjct: 620 SYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGN 679 Query: 665 ARVGYNYSDNGSQQQLNYALSGSLVAHSQGITLGQSLGETNVLIAAPGAENTRVANSTGL 724 A +GY++SD+ +QL Y +SG ++AH+ G+TLGQ L +T VL+ APGA++ +V N TG+ Sbjct: 680 ANIGYSHSDD--IKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGV 737 Query: 725 KTDWRGYTVVPYATSYRENRIALDAASLKRNVDLENAVVNVVPTKGALVLAEFNAHAGAR 784 +TDWRGY V+PYAT YRENR+ALD +L NVDL+NAV NVVPT+GA+V AEF A G + Sbjct: 738 RTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIK 797 Query: 785 VLMKTSKQGIPLRFGAIATLDGVQANSGIIDDDGSLYMAGLPAKGTISVRWGEAPDQICH 844 +LM + PL FGA+ T + +SGI+ D+G +Y++G+P G + V+WGE + C Sbjct: 798 LLMTLTHNNKPLPFGAMVTSES-SQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCV 856 Query: 845 INYELTEQQINSAITRMDAICR 866 NY+L + +T++ A CR Sbjct: 857 ANYQLPPESQQQLLTQLSAECR 878
>CLENTEROTOXN#Clostridium enterotoxin signature. Length = 319 Score = 31.6 bits (71), Expect = 0.004 Identities = 13/48 (27%), Positives = 22/48 (45%) Query: 295 VGVVVTDSQNNIISPAGGTLPLSIPDDADSIARMNVYPVSTTGVPPET 342 + V TD + I+ A T L++ D +S N+Y ++ P T Sbjct: 188 LTVPSTDIEKEILDLAAATERLNLTDALNSNPAGNLYDWRSSNSYPWT 235
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 75.4 bits (185), Expect = 3e-18 Identities = 44/176 (25%), Positives = 71/176 (40%), Gaps = 23/176 (13%) Query: 13 TFDPQQSALIVVDMQNAYATPGGYLDLAGFDVSTTRPVIANIQTAVTAARAAGMLIIWFQ 72 DP ++ L++ DMQN + +D S + ANI+ G+ +++ Sbjct: 25 VPDPNRAVLLIHDMQNYF------VDAFTAGASPVTELSANIRKLKNQCVQLGIPVVY-- 76 Query: 73 NGWDEQYVEAGGPGSPNFHKSNALKTMRKQPQLQGKLLAKGSWDYQLVDELVPQPGDIVL 132 PGS N L G L G ++ +++ EL P+ D+VL Sbjct: 77 ---------TAQPGSQNPDDRALLTDF------WGPGLNSGPYEEKIITELAPEDDDLVL 121 Query: 133 PKPRYSGFFNTPLDSILRSRGIRHLVFTGIATNVCVESTLRDGFFLEYFGVVLEDA 188 K RYS F T L ++R G L+ TGI ++ T + F + + DA Sbjct: 122 TKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDA 177
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 65.8 bits (160), Expect = 2e-15 Identities = 30/165 (18%), Positives = 62/165 (37%), Gaps = 8/165 (4%) Query: 10 GKRSRAVSAKKKAILSAALDTFSQFGFHGTRLEQIAELAGVSKTNLLYYFPSKEALYIAV 69 K + ++ IL AL FSQ G T L +IA+ AGV++ + ++F K L+ + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 70 LRQILDIWLAPLKAFREDF--APLAAIKEYIRLKLEVSRDYPQASRLFCM-----EMLAG 122 ++ F PL+ ++E + LE + + L + E + Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 123 APLLMDELTGDLKALIDEKSALIAGWVKSGKL-APIDPQHLIFMI 166 ++ D + +++ L A + + ++ Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIM 167
>ARGDEIMINASE#Bacterial arginine deiminase signature. Length = 409 Score = 29.8 bits (67), Expect = 0.047 Identities = 27/183 (14%), Positives = 61/183 (33%), Gaps = 23/183 (12%) Query: 450 WPRAAENELKK-AEVIEPRNINLEVEQAWTALTLQEWQQA--AVLTHDVVEREPQDPGVV 506 + A E + A +++ + +E + + L ++ ++E E + + Sbjct: 47 YLEVARQEHEVFASILKNNLVEIEYIEDLISEVLVSSVALENKFISQFILEAEIKTDFTI 106 Query: 507 -RLK---RAVDVHNLAELRIAGSTGIDAEGPDSGKHDVDLTTIVYS---PPLKDNWRGFA 559 LK ++ + N+ I+G E + DL P+ + F Sbjct: 107 NLLKDYFSSLTIDNMISKMISGVVT--EELKNYTSSLDDLVNGANLFIIDPMPNVL--FT 162 Query: 560 GFGYADGQFSEGKGIVRDWLAGVEWRSRNIWLEAEYAERVFNHEHKPGARLSGWYDFNDN 619 D S G G+ + + + R E +AE +F + + W + + Sbjct: 163 ----RDPFASIGNGVT---INKMFTKVRQ--RETIFAEYIFKYHPVYKENVPIWLNRWEE 213 Query: 620 WRI 622 + Sbjct: 214 ASL 216
>BINARYTOXINA#Clostridial binary toxin A signature. Length = 454 Score = 29.6 bits (66), Expect = 0.027 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 6/77 (7%) Query: 335 DQVIKTVVNIIGKSIRPDDLLA--RVGGEEFGVLLTDIDTERAKALAERIRENVERLTGD 392 D + + N + + P +L+ R G +EFG+ LT + + K E I E+ G Sbjct: 313 DSKVNNIENALKLTPIPSNLIVYRRSGPQEFGLTLTSPEYDFNK--IENIDAFKEKWEGK 370 Query: 393 NPEYAIPQKVTISIGAV 409 Y P ++ SIG+V Sbjct: 371 VITY--PNFISTSIGSV 385
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 41.5 bits (97), Expect = 5e-06 Identities = 17/49 (34%), Positives = 29/49 (59%) Query: 354 TLTNGALEASNVDLSKELVNMIVAQRNYQSNAQTIKTQDQILNTLVNLR 402 L+N S V+L +E N+ Q+ Y +NAQ ++T + I + L+N+R Sbjct: 498 QLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR 546 Score = 36.9 bits (85), Expect = 1e-04 Identities = 22/56 (39%), Positives = 30/56 (53%), Gaps = 4/56 (7%) Query: 6 AVSGLNAAATNLDVIGNNIANSATYGFKSGTASFAD----MFAGSKVGLGVKVAGI 57 A+SGLNAA L+ NNI++ G+ T A + AG VG GV V+G+ Sbjct: 7 AMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVSGV 62
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 43.8 bits (103), Expect = 4e-07 Identities = 18/81 (22%), Positives = 36/81 (44%), Gaps = 14/81 (17%) Query: 3 SSLWIAKTGLDAQQTNMDVIANNLANVSTNGFKRQRAVFEDLLYQTIRQPGAQSSEQTTL 62 S + A +GL+A Q ++ +NN+++ + G+ RQ + + +TL Sbjct: 2 SLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTI--------------MAQANSTL 47 Query: 63 PSGLQIGTGVRPVATERLHSQ 83 +G +G GV +R + Sbjct: 48 GAGGWVGNGVYVSGVQREYDA 68 Score = 41.1 bits (96), Expect = 3e-06 Identities = 11/41 (26%), Positives = 21/41 (51%) Query: 220 ETSNVNVAEELVNMIQVQRAYEINSKAVSTTDQMLQKLTQL 260 S VN+ EE N+ + Q+ Y N++ + T + + L + Sbjct: 505 SISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 349 bits (897), Expect = e-126 Identities = 232/232 (100%), Positives = 232/232 (100%) Query: 1 MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINY 60 MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINY Sbjct: 1 MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINY 60 Query: 61 GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNA 120 GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNA Sbjct: 61 GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNA 120 Query: 121 RADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRF 180 RADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRF Sbjct: 121 RADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRF 180 Query: 181 SGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM 232 SGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM Sbjct: 181 SGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM 232
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 427 bits (1100), Expect = e-152 Identities = 157/363 (43%), Positives = 213/363 (58%), Gaps = 9/363 (2%) Query: 4 FLSALILLLVTTAAQAERIRDLTSVQGVRQNSLIGYGLVVGLDGTGDQTTQTPFTTQTLN 63 F + L A RI+D+ S+Q R N LIGYGLVVGL GTGD +PFT Q++ Sbjct: 13 FSALPFLSTPPAQADTSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFTEQSMR 72 Query: 64 NMLSQLGITVPTGTNMQLKNVAAVMVTASLPPFGRQGQTIDVVVSSMGNAKSLRGGTLLM 123 ML LGIT G + KN+AAVMVTA+LPPF G +DV VSS+G+A SLRGG L+M Sbjct: 73 AMLQNLGITTQGGQS-NAKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRGGNLIM 131 Query: 124 TPLKGVDSQVYALAQGNILVGGAGASAGGSSVQVNQLNGGRITNGAVIERELPSQFGVGN 183 T L G D Q+YA+AQG ++V G A +++ R+ NGA+IERELPS+F Sbjct: 132 TSLSGADGQIYAVAQGALIVNGFSAQGDAATLTQGVTTSARVPNGAIIERELPSKFKDSV 191 Query: 184 TLNLQLNDEDFSMAQQIADTINRVR----GYGSATALDARTIQVRVPSGNSSQVRFLADI 239 L LQL + DFS A ++AD +N G A D++ I V+ P + R +A+I Sbjct: 192 NLVLQLRNPDFSTAVRVADVVNAFARARYGDPIAEPRDSQEIAVQKPRV-ADLTRLMAEI 250 Query: 240 QNMQVNVTPQDAKVVINSRTGSVVMNREVTLDSCAVAQGNLSVTVNRQANVSQPDTPFGG 299 +N+ V T AKVVIN RTG++V+ +V + AV+ G L+V V V QP PF Sbjct: 251 ENLTVE-TDTPAKVVINERTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQP-APFSR 308 Query: 300 GQTVVTPQTQIDLRQSGGSLQSVRSSASLNNVVRALNALGATPMDLMSILQSMQSAGCLR 359 GQT V PQT I Q G + ++ L +V LN++G +++ILQ ++SAG L+ Sbjct: 309 GQTAVQPQTDIMAMQEGSKV-AIVEGPDLRTLVAGLNSIGLKADGIIAILQGIKSAGALQ 367 Query: 360 AKL 362 A+L Sbjct: 368 AEL 370
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 511 bits (1318), Expect = 0.0 Identities = 313/313 (100%), Positives = 313/313 (100%) Query: 1 MISDSKLLASAAWDAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALPKDG 60 MISDSKLLASAAWDAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALPKDG Sbjct: 1 MISDSKLLASAAWDAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALPKDG 60 Query: 61 LFSSEHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEESTPAAPMKFPLET 120 LFSSEHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEESTPAAPMKFPLET Sbjct: 61 LFSSEHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEESTPAAPMKFPLET 120 Query: 121 VVRYQNQALSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQAAL 180 VVRYQNQALSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQAAL Sbjct: 121 VVRYQNQALSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQAAL 180 Query: 181 ESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYL 240 ESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYL Sbjct: 181 ESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYL 240 Query: 241 EALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQMKSISDK 300 EALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQMKSISDK Sbjct: 241 EALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQMKSISDK 300 Query: 301 VSKTYSMNIDNLF 313 VSKTYSMNIDNLF Sbjct: 301 VSKTYSMNIDNLF 313
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 682 bits (1762), Expect = 0.0 Identities = 545/546 (99%), Positives = 545/546 (99%) Query: 2 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMEQANSTLGAGGWVGNGVYVS 61 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIM QANSTLGAGGWVGNGVYVS Sbjct: 1 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVS 60 Query: 62 GVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLV 121 GVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLV Sbjct: 61 GVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLV 120 Query: 122 SNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLND 181 SNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLND Sbjct: 121 SNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLND 180 Query: 182 QISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTA 241 QISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTA Sbjct: 181 QISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTA 240 Query: 242 RQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQL 301 RQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQL Sbjct: 241 RQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQL 300 Query: 302 ALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGDVAIGATVTDASAVLATD 361 ALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGDVAIGATVTDASAVLATD Sbjct: 301 ALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGDVAIGATVTDASAVLATD 360 Query: 362 YKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPVSDAIV 421 YKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPVSDAIV Sbjct: 361 YKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPVSDAIV 420 Query: 422 NMDVLITDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGN 481 NMDVLITDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGN Sbjct: 421 NMDVLITDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGN 480 Query: 482 KTATLKTSSATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFD 541 KTATLKTSSATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFD Sbjct: 481 KTATLKTSSATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFD 540 Query: 542 ALINIR 547 ALINIR Sbjct: 541 ALINIR 546
>FLAGELLIN#Flagellin signature. Length = 507 Score = 45.4 bits (107), Expect = 2e-07 Identities = 30/132 (22%), Positives = 60/132 (45%), Gaps = 3/132 (2%) Query: 7 MMYQQNMRGITNSQAEWMKYGEQMSTGKRVVNPSDDPIAASQAVVLSQAQAQNSQYTLAR 66 ++ Q N+ +S + + E++S+G R+ + DD + A + +Q + Sbjct: 11 LLTQNNLNKSQSSLSSAI---ERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQASRNA 67 Query: 67 TFATQKVSLEESVLSQVTTAIQNAQEKIVYASNGTLSDDDRASLATDIQGLRDQLLNLAN 126 E L+++ +Q +E V A+NGT SD D S+ +IQ +++ ++N Sbjct: 68 NDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEEIDRVSN 127 Query: 127 TTDGNGRYIFAG 138 T NG + + Sbjct: 128 QTQFNGVKVLSQ 139
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 64.7 bits (157), Expect = 2e-12 Identities = 47/288 (16%), Positives = 83/288 (28%), Gaps = 36/288 (12%) Query: 513 PSEEEFAERKRPEQPALATFAMPDVPPAPT-PAEPAAPVVAPAPKAAPATPVAPAQPGLL 571 P E+ + DVP P+ E A AP P APATP Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETT----- 1037 Query: 572 SRFFGALKALFSGGEETKPTEQPAPKAEAKPERQQDRRKPRQNNRRDRNERRDTRSER-- 629 ET + Q QN + + + ++ Sbjct: 1038 ---------------ETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQT 1082 Query: 630 TEGSDNREENRRNRRQAQQQTAETRESRQQAEVTEKARTADEQQAPRRERSRRRNDDKRQ 689 E + + E + + ++TA + + TEK + + + + + + Q Sbjct: 1083 NEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQ 1142 Query: 690 AQ---QEAKALNVEEQSVQETEQEERVRPVQPRRKQRQLNQKVRYEQSV--AEEAVVAPV 744 A+ + +N++E Q + +P + + Q V +V V P Sbjct: 1143 AEPARENDPTVNIKEPQSQTNTTADTEQPA--KETSSNVEQPVTESTTVNTGNSVVENPE 1200 Query: 745 VEETVAAEPIVQEAPA------PRTELVKVPLPVVAQTAPEQQEENNA 786 +P V + R + VP V T A Sbjct: 1201 NTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVA 1248 Score = 63.2 bits (153), Expect = 5e-12 Identities = 46/261 (17%), Positives = 83/261 (31%), Gaps = 26/261 (9%) Query: 551 VAPAPKAAPATPVAPAQPGLLSRFFGALKALFSGGEETKPTEQP-APKAEAKPERQQDRR 609 + P + S E + E P P A A P Sbjct: 991 TVDTTNITTPNNIQADVPSVPSN----------NEEIARVDEAPVPPPAPATPSETT--- 1037 Query: 610 KPRQNNRRDRNERRDTRSERTEGSDNREENRRNRRQAQQQTAETRESRQQAEV------T 663 N ++++++ D E +NR A++ + + + Q EV T Sbjct: 1038 -----ETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSET 1092 Query: 664 EKARTADEQQAPRRERSRRRNDDKRQAQQEAKALNVEEQSVQETEQEERVRPVQPRRKQR 723 ++ +T + ++ E+ + + + Q+ K + + QE + + + R Sbjct: 1093 KETQTTETKETATVEKEEKAKVETEKTQEVPK-VTSQVSPKQEQSETVQPQAEPARENDP 1151 Query: 724 QLNQKVRYEQSVAEEAVVAPVVEETVAAEPIVQEAPAPRTELVKVPLPVVAQTAPEQQEE 783 +N K Q+ P E + E V E+ T V P A Q Sbjct: 1152 TVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTV 1211 Query: 784 NNADNRDNGGMPRRSRRSPRH 804 N+ + RRS RS H Sbjct: 1212 NSESSNKPKNRHRRSVRSVPH 1232
>CHLAMIDIAOMP#Chlamydia major outer membrane protein signature. Length = 393 Score = 28.4 bits (63), Expect = 0.044 Identities = 19/67 (28%), Positives = 28/67 (41%), Gaps = 8/67 (11%) Query: 137 GVNGDAVDPKSVTSWADL------WKPEYKGSLLLTDDAREVFQMALRKLGYSGNTTDPK 190 G GD DP T+W D + ++ +L D + FQM + +GN T P Sbjct: 42 GFGGDPCDP--CTTWCDAISMRMGYYGDFVFDRVLKTDVNKEFQMGDKPTSTTGNATAPT 99 Query: 191 EIEAAYN 197 + A N Sbjct: 100 TLTAREN 106
>HOKGEFTOXIC#Hok/Gef cell toxic protein family signature. Length = 52 Score = 67.2 bits (164), Expect = 3e-19 Identities = 19/46 (41%), Positives = 32/46 (69%) Query: 23 QKAMLIALIVICLTVIVTALVTRKDLCEVRIRTGQTEVAVFTAYEP 68 + +++ ++++CLT+++ +TRK LCE+R R G EVA F AYE Sbjct: 5 RSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYES 50
>PF06291#Lambda prophage Bor protein Length = 102 Score = 174 bits (441), Expect = 1e-60 Identities = 95/97 (97%), Positives = 96/97 (98%) Query: 1 MKKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKETITHHFFVSGIGQEKTVDAAKICGG 60 MKKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKETITHHFFVSGIGQ+KTVDAAKICGG Sbjct: 6 MKKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKETITHHFFVSGIGQKKTVDAAKICGG 65 Query: 61 AENVVKTETQQTFVNGFLGFITLGIYTPLEARVYCSQ 97 AENVVKTETQQTFVNG LGFITLGIYTPLEARVYCSQ Sbjct: 66 AENVVKTETQQTFVNGLLGFITLGIYTPLEARVYCSQ 102
>cloacin#Cloacin signature. Length = 551 Score = 32.4 bits (73), Expect = 0.003 Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 6/88 (6%) Query: 36 EWNRAKAELDALDEQIAREEELRRQDQAYVDESGPEERQNNEAENGKKAVEEKRAAAFNR 95 + RA+AEL+ +E +AR +E QA + + +A N A FNR Sbjct: 322 NYERARAELNQANEDVARNQE----RQAKAVQVYNSRKSELDAANKTLADAIAEIKQFNR 377 Query: 96 FLRAGFAELNAEERNLMRELRAQSVTTD 123 F A + + M L+AQ TD Sbjct: 378 FAHDPMAGGHRMWQ--MAGLKAQRAQTD 403
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 42.4 bits (99), Expect = 4e-06 Identities = 30/115 (26%), Positives = 57/115 (49%), Gaps = 7/115 (6%) Query: 387 GTTTLKLSENTIWNMKDDSVVTHLTNSDSIINL-SYDDGQTFTQGKTLTVKGNYVGNNGQ 445 G + ++L+EN+ W++ +S V L ++ I+L S D+ T+ TLTV N + NG Sbjct: 842 GNSQVRLTENSHWHLTGNSDVHQLDLANGHIHLNSADNSNNVTKYNTLTV--NSLSGNGS 899 Query: 446 LNIRTVLGDDKSATDRLIVEGNTSGSTTVYVKNAGGSGAATLNGIELITVNGDES 500 T L + + D+++V + +G+ T+ V + G N + L + + Sbjct: 900 FYYLTDLSNKQG--DKVVVTKSATGNFTLQVADKTGE--PNHNELTLFDASKAQR 950
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 62.4 bits (151), Expect = 1e-12 Identities = 53/225 (23%), Positives = 83/225 (36%), Gaps = 39/225 (17%) Query: 110 WRLGVMAGYARDYNLTHSSVSDYRSKGSVRGYSAGLYATWFADDISKKGAYIDSWAQYSW 169 W LG +AGY R + G G YAT+ AD G Y+D+ + S Sbjct: 690 WHLGGLAGYTR----GDRGFTGDGG-GHTDSVHVGGYATYIADS----GFYLDATLRASR 740 Query: 170 FKN----------SVKGDELAYESYSAKGATVSLEAGYGFALNKSFGLEAAKYTWIFQPQ 219 +N +VKG Y G SLEAG F W +PQ Sbjct: 741 LENDFKVAGSDGYAVKGK------YRTHGVGASLEAGRRFTHADG---------WFLEPQ 785 Query: 220 AQAIWMGVDHNAHTEANGSRIENDANNNIQTRLGFRTFIRTQEKNSGPHGDDFEPFVEMN 279 A+ A+ ANG R+ ++ +++ RLG R + G +P+++ + Sbjct: 786 AELAVFRAGGGAYRAANGLRVRDEGGSSVLGRLGLEVGKRIELAG----GRQVQPYIKAS 841 Query: 280 WIHNSK-DFAVSMNGVKVEQDGASNLGEIKLGVNGNLNPAASVWG 323 + V NG+ + E+ LG+ L S++ Sbjct: 842 VLQEFDGAGTVHTNGIAHRTELRGTRAELGLGMAAALGRGHSLYA 886
>SECA#SecA protein signature. Length = 901 Score = 57.2 bits (138), Expect = 2e-12 Identities = 16/28 (57%), Positives = 20/28 (71%) Query: 125 IDGTRPQFGRNDPCPCGSGKKFKKCCGQ 152 + GRNDPCPCGSGKK+K+C G+ Sbjct: 872 AQTGERKVGRNDPCPCGSGKKYKQCHGR 899
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.5 bits (222), Expect = 7e-22 Identities = 40/152 (26%), Positives = 64/152 (42%), Gaps = 3/152 (1%) Query: 10 ILIVEDEQVFRSLLDSWFSSLGATTVLAADGVDALELLGGFTPDLMICDIAMPRMNGLKL 69 IL+ +D+ R++L+ S G + ++ + DL++ D+ MP N L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 70 LEHIRNRGDQTPVLVISATENMADIAKALRLGVEDVLLKPVKDLNRLREMVFACLYPSMF 129 L I+ PVLV+SA KA G D L KP DL L ++ L + Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPF-DLTELIGIIGRAL--AEP 122 Query: 130 NSRVEEEERLFRDWDAMVDNPAAAAKLLQELQ 161 R + E +D +V AA ++ + L Sbjct: 123 KRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLA 154
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.6 bits (69), Expect = 0.008 Identities = 9/16 (56%), Positives = 11/16 (68%) Query: 55 VVGESGCGKSTFARAI 70 + GESG GK ARA+ Sbjct: 165 ITGESGTGKELVARAL 180
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 31.2 bits (70), Expect = 4e-04 Identities = 16/57 (28%), Positives = 20/57 (35%), Gaps = 2/57 (3%) Query: 41 GPMPAVDSNDPGAAGFTGSTVIAEFESLEAAQAWADADPYVAAGVYEHVSVKPFKKV 97 P+PA G GS E + EA W +P A V +V KV Sbjct: 268 APLPA--EGKFAVIGGLGSVAGFEKNTREAVDRWIQENPNAAETVEAVFNVAAAAKV 322
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 262 bits (670), Expect = 6e-91 Identities = 239/239 (100%), Positives = 239/239 (100%) Query: 6 MTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVTPADLEPPQA 65 MTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVTPADLEPPQA Sbjct: 1 MTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVTPADLEPPQA 60 Query: 66 VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESR 125 VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESR Sbjct: 61 VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESR 120 Query: 126 PASPFENTAPARLTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKF 185 PASPFENTAPARLTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKF Sbjct: 121 PASPFENTAPARLTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKF 180 Query: 186 DVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGIVVNILFKINGTTEIQ 244 DVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGIVVNILFKINGTTEIQ Sbjct: 181 DVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGIVVNILFKINGTTEIQ 239
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 341 bits (877), Expect = e-117 Identities = 125/341 (36%), Positives = 182/341 (53%), Gaps = 23/341 (6%) Query: 6 DNLLGEANSFLEVLEQVSHLAPLDKPVLIIGERGTGKELIASRLHYLSSRWQGPFISLNC 65 L+G + + E+ ++ L D ++I GE GTGKEL+A LH R GPF+++N Sbjct: 137 MPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINM 196 Query: 66 AALNENLLDSELFGHEAGAFTGAQKRHPGRFERADGGTLFLDELATAPMMVQEKLLRVIE 125 AA+ +L++SELFGHE GAFTGAQ R GRFE+A+GGTLFLDE+ PM Q +LLRV++ Sbjct: 197 AAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQ 256 Query: 126 YGELERVGGSQPLQVNVRLVCATNADLPAMVNEGTFRADLLDRLAFDVVQLPPLRERESD 185 GE VGG P++ +VR+V ATN DL +N+G FR DL RL ++LPPLR+R D Sbjct: 257 QGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAED 316 Query: 186 IMLMAEYFAIQMCREIKLPLFPGFTERARETLLNYRWPGNIRELKNVVERSVYRHGTSDY 245 I + +F Q +E F + A E + + WPGN+REL+N+V R + Sbjct: 317 IPDLVRHFVQQAEKEGLDVK--RFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVI 374 Query: 246 PLDDIIID---PFKRRPPEDAIAVSETTSLPTLPLD------------------LREFQM 284 + I + P E A A S + S+ + Sbjct: 375 TREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLA 434 Query: 285 QQEKELLQLSLQQGKYNQKRAAELLGLTYHQFRALLKKHQI 325 + E L+ +L + NQ +AA+LLGL + R +++ + Sbjct: 435 EMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGV 475
>MPTASEINHBTR#Metalloprotease inhibitor signature. Length = 122 Score = 24.6 bits (53), Expect = 0.030 Identities = 7/43 (16%), Positives = 17/43 (39%) Query: 30 SGRSELSQSEQQRLAQLADEAKRMRERIQALESILDAEHPNWR 72 +G+ + + A A++A + + E L + +W Sbjct: 37 AGQLGIEATGSGVCAGPAEQANALAGDVACAEQWLGDKPVSWS 79
>PF08280#M protein trans-acting positive regulator Length = 530 Score = 29.8 bits (67), Expect = 0.016 Identities = 10/36 (27%), Positives = 16/36 (44%) Query: 185 RVEECWHLTEQNAMYETFIQSFRPLVPLLKEAADEL 220 + +C L E+N + + L+P LKE L Sbjct: 311 HIRQCCQLFEENDTFRLLLNPIITLLPNLKEQKASL 346
>FLAGELLIN#Flagellin signature. Length = 507 Score = 38.1 bits (88), Expect = 8e-05 Identities = 37/336 (11%), Positives = 76/336 (22%), Gaps = 9/336 (2%) Query: 161 NGKTTVDGKDSTGTEINGNNGKVIQDGDLDVSGGGHGIDITGDSATVDNKGTMTVTDPES 220 NG + + ++ N+G+ I + + D V+ TV D Sbjct: 132 NGVKVLSQDNQMKIQVGANDGETITIDLQKIDVK----SLGLDGFNVNGPKEATVGDL-- 185 Query: 221 MGIQIDGDKAIVNNEGESTITNGGTGTQINGDDATANN-NGKTTVDGKDSTGTEINGNNG 279 + + D TA K V+ + T + N Sbjct: 186 -KSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTDDAENN 244 Query: 280 KVIQDGDLDVSGGGHGIDITGDSATVDNKGTMTVTDPESIGIQVDGDQAVVNNEGESAIT 339 + S G + + + D + + +D N S Sbjct: 245 TAVDLFKTTKSTAG-TAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGNGKVSTTI 303 Query: 340 NGGTGTQINGDDATANNNGKTTVDGKDSTGTEIAGNNGKVIQDGDLDVSGGGHGIDITGD 399 NG T D N N D + S ++ Sbjct: 304 NGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSDLEANNA 363 Query: 400 SATVDNKGTMTVTDPESIGIQIDGDQAIVNNEGESTITNGGTGTQINGNDATANNSGKTT 459 + ++ + + + + Sbjct: 364 VKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINEDAAAAKKSTANPLAS 423 Query: 460 VDGKDSTGTKIAGNIGIVNLDGSLTVTGGAHGVENI 495 +D S + ++G + +T + V N+ Sbjct: 424 IDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNL 459 Score = 35.0 bits (80), Expect = 7e-04 Identities = 43/277 (15%), Positives = 76/277 (27%), Gaps = 14/277 (5%) Query: 248 QINGDDATANNNGKTTVDGKDSTGTEINGNNGKVIQ-----------DGDLDVSGGGHGI 296 +I+ NG + + ++ N+G+ I D G Sbjct: 121 EIDRVSNQTQFNGVKVLSQDNQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKEA 180 Query: 297 DITGDSATVDNKGTMTVTDPESIGIQVDGDQAVVNNEGESAITNGGTGTQINGDDATANN 356 + ++ N + +VD + V + + T ++ Sbjct: 181 TVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTDD 240 Query: 357 NGKTTVDGKDSTGTEIAGNNGKVIQDGDLDVSGGGHGIDITGDSATVDNKGTMTVTDPES 416 T T AG G + G D G + T+D K S Sbjct: 241 AENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGNGKVS 300 Query: 417 IGIQIDGDQAIVNNEGESTITNGGTGTQINGNDATANNSGKTTVDGK---DSTGTKIAGN 473 I + V + Q + N T+ +G+ T D K +S Sbjct: 301 TTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSDLEA 360 Query: 474 IGIVNLDGSLTVTGGAHGVENIGDNGTVNNKGVMTPT 510 V + +TV G + GD T+ K + Sbjct: 361 NNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDK 397
>PF03944#delta endotoxin Length = 633 Score = 32.0 bits (72), Expect = 0.020 Identities = 54/204 (26%), Positives = 75/204 (36%), Gaps = 31/204 (15%) Query: 855 IMNISGTGAVAMEGDKNAQLVNNGTINLGTAGTTDTGMIGMQLDANATAD---AVIENNG 911 I NISG V D L N N+ + T G + + + AV EN Sbjct: 423 IRNISGVPLVVRNEDLRRPLHYNEIRNIASPSGTPGGARAYMVSVHNRKNNIHAVHENGS 482 Query: 912 TINIFANDSFAFSVLGTVGHVVNNGTVVIADGVTGSGLIKQGDSINVEGMNGN------- 964 I++ ND F++ VNN T G+ QGDS+ E N Sbjct: 483 MIHLAPNDYTGFTISPIHATQVNNQTRTFISEKFGN----QGDSLRFEQNNTTARYTLRG 538 Query: 965 NGNSSEVHYGDYTLPDVPKPNTVSVTSGSDEAGGSMNNLNGYV-VGTNVNGSAGKLKVNN 1023 NGNS Y Y +T+ VT +NG V TNVN + VN+ Sbjct: 539 NGNS----YNLYLRVSSIGNSTIRVT------------INGRVYTATNVNTTTNNDGVND 582 Query: 1024 ASMNGVEINTGFTAGTADTTVSFD 1047 +IN G ++++ V D Sbjct: 583 NGARFSDINIGNVVASSNSDVPLD 606
>FIMBRIALPAPF#Escherichia coli: P pili tip fibrillum papF protein signature. Length = 167 Score = 32.0 bits (72), Expect = 5e-04 Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 7/93 (7%) Query: 16 LFTATLQAADVTITVNGRVVAKPCTIQT-KEANVNLGDLYTRNLQQPGSASGWHNITLSL 74 L T+ ADV I + G V PCTI + V+ G++ N + ++ G +S+ Sbjct: 11 LLTSVAVLADVQINIRGNVYIPPCTINNGQNIVVDFGNI---NPEHVDNSRGEVTKNISI 67 Query: 75 TDCPVETSAVTAIVTGSTDNTGYYKNEGTAENI 107 + CP ++ ++ VTG+T G +N A NI Sbjct: 68 S-CPYKSGSLWIKVTGNTMGVG--QNNVLATNI 97
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 53.3 bits (128), Expect = 7e-10 Identities = 41/192 (21%), Positives = 83/192 (43%), Gaps = 8/192 (4%) Query: 36 LSDIAQSFHMQTAQVGIMLTIYAWVVALMSLPFMLMTSQVERRKLLICLFVVFIASHVLS 95 L DIA F+ A + T + ++ + + ++ Q+ ++LL+ ++ V+ Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 96 FLSWS-FTVLVISRIGVAFAHAIFWSITASLAIRMAPAGKRAQALSLIATGTALAMVLGL 154 F+ S F++L+++R A F ++ + R P R +A LI + A+ +G Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 155 PLGRIVGQYFGWRMTFFAIGIGALITLLCLIKLLPLLPSEHSGSLKSLPLLFRRPALMSI 214 +G ++ Y W I + +IT+ L+KLL + LMS+ Sbjct: 157 AIGGMIAHYIHWSY-LLLIPMITIITVPFLMKLLK------KEVRIKGHFDIKGIILMSV 209 Query: 215 YLLTVVVVTAHY 226 ++ ++ T Y Sbjct: 210 GIVFFMLFTTSY 221
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 42.9 bits (101), Expect = 1e-06 Identities = 42/239 (17%), Positives = 82/239 (34%), Gaps = 18/239 (7%) Query: 7 RSTSALLASSLLLTIGRGATLPFMTIYLSRQYSLSVDLI---GYAMTIALTIGVVFSLGF 63 R +L++ L +G G +P + L R S D+ G + + + + Sbjct: 5 RPLIVILSTVALDAVGIGLIMPVLPGLL-RDLVHSNDVTAHYGILLALYALMQFACAPVL 63 Query: 64 GILADKFDKKRYMLLAITAFASGFIAIPLVNNVTLVVLFFALINCAYSVFATVLKAWFAD 123 G L+D+F ++ +L+++ A + + + ++ + + + A A+ AD Sbjct: 64 GALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAG-AYIAD 122 Query: 124 NLSSTSKTKIFSINYTMLNIGWTIGPPLGTLLVMQSINLPFWLAAICSAFPMLFIQIWVK 183 + + F G GP LG L+ S + PF+ AA + L + Sbjct: 123 ITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLP 182 Query: 184 RSEK---------IIATETGSVWSPKVLLQDKALLWFTCSGFLASFVSGAFASCISQYV 233 S K + W + A L F+ V A+ + Sbjct: 183 ESHKGERRPLRREALNPLASFRW--ARGMTVVAALMAV--FFIMQLVGQVPAALWVIFG 237 Score = 32.5 bits (74), Expect = 0.003 Identities = 22/155 (14%), Positives = 60/155 (38%), Gaps = 2/155 (1%) Query: 7 RSTSALLASSLLLTIGRGATLPFMTIYLSRQYSLSVDLIGYAMTIALTIGVVF-SLGFGI 65 +AL+A ++ + I+ ++ IG ++ + + ++ G Sbjct: 210 TVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGP 269 Query: 66 LADKFDKKRYMLLAITAFASGFIAIPLVNNVTLVVLFFALINCAYSVFATVLKAWFADNL 125 +A + ++R ++L + A +G+I + + L+ + L+A + + Sbjct: 270 VAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASG-GIGMPALQAMLSRQV 328 Query: 126 SSTSKTKIFSINYTMLNIGWTIGPPLGTLLVMQSI 160 + ++ + ++ +GP L T + SI Sbjct: 329 DEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASI 363
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 100 bits (249), Expect = 2e-27 Identities = 70/244 (28%), Positives = 114/244 (46%), Gaps = 16/244 (6%) Query: 2 IVLVTGATAGFGECITRRFIQQGHKVIATGRRQERLQELKDELGDNLYIAQ---LDVRNR 58 I +TGA G GE + R QG + A E+L+++ L A+ DVR+ Sbjct: 10 IAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDS 69 Query: 59 AAIEEMLASLPAEWCNIDILVNNAGLALGMEPAHKASVEDWETMIDTNNKGLVYMTRAVL 118 AAI+E+ A + E IDILVN AG+ L H S E+WE N+ G+ +R+V Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGV-LRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 119 PGMVERNHGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLNLRTDLHGTAVRVTDIEPG 178 M++R G I+ +GS P Y ++KA F+ L +L +R + PG Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 179 LVGGTEFSNVRFKGDDGKAE------KTYQNTVALT----PEDVSEAV-WWVSTLPAHVN 227 T+ + ++G + +T++ + L P D+++AV + VS H+ Sbjct: 189 ST-ETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHIT 247 Query: 228 INTL 231 ++ L Sbjct: 248 MHNL 251
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 48.7 bits (116), Expect = 3e-08 Identities = 33/118 (27%), Positives = 55/118 (46%), Gaps = 16/118 (13%) Query: 72 VGAFIFGKMGDRIGRKKVLFITITMMGICTTLIGVLPTYAQIGVFAPILLVTLRIIQGLG 131 +G ++GK+ D++G K++L I + + + V ++ + + A R IQG G Sbjct: 64 IGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMA-------RFIQGAG 116 Query: 132 AGAEISGAGTMLAEYAPKGKR----GIISSFVAMGTNCGTLSATAI-----WAFMFFI 180 A A + ++A Y PK R G+I S VAMG G I W+++ I Sbjct: 117 AAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLI 174
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 30.6 bits (69), Expect = 0.010 Identities = 58/311 (18%), Positives = 107/311 (34%), Gaps = 16/311 (5%) Query: 61 FAGLLSDRFGRRPFIMLGMCCYMAFFFGILQTNNIIIAYVFGFLAGMANSFLDAGTYPSL 120 G LSDRFGRRP +++ + + + + + Y+ +AG+ + A + Sbjct: 62 VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATG-AVAGAYI 120 Query: 121 MEAFPRSPGTANI-LIKAFVSSGQFLLPLIISLLVWAELWFGWSFMIAAGIMFINALFLY 179 + + + A G P++ L+ F AA + +N L Sbjct: 121 ADITDGDERARHFGFMSACFGFGMVAGPVLGGLM--GGFSPHAPFFAAAALNGLNFLTGC 178 Query: 180 RCTFPPHPGRRLPV---IKKTTSSTEHRCSIIDLASYTLYGYISMATFYLVSQWLAQYGQ 236 H G R P+ +S + +A+ +I + + +G+ Sbjct: 179 FLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGE 238 Query: 237 FVAGMSYTM-SIKLLSIYTVGSLLCVFITAPLIRNTVRPTTLLMLYTFISFIALFTVCLH 295 T I L + + SL IT P+ L++ IA T + Sbjct: 239 DRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALML-----GMIADGTGYIL 293 Query: 296 PTFYVVIIFAF-VIGFTSAGGVVQIGLTLMAERF--PYAKGKATGIYYSAGSIATFTIPL 352 F AF ++ ++GG+ L M R +G+ G + S+ + PL Sbjct: 294 LAFATRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPL 353 Query: 353 ITAHLSQRSIA 363 + + SI Sbjct: 354 LFTAIYAASIT 364
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 30.6 bits (69), Expect = 0.011 Identities = 38/177 (21%), Positives = 75/177 (42%), Gaps = 9/177 (5%) Query: 12 ILAVLCIYFSYFLHGISVITLAQNMSSLAEKFSTDNAGIAYLISGIGLGRLISILFFGVI 71 IL LCI F ++ + L ++ +A F+ A ++ + L I +G + Sbjct: 15 ILIWLCIL--SFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKL 72 Query: 72 SDKFGRRAVILMAVIMY----LLFFFGIPACPNLTLAYGLAVCVGIANSALDTGGYPALM 127 SD+ G + ++L +I+ ++ F G L +A + A AL Sbjct: 73 SDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARY- 131 Query: 128 ECFPKASGSAVILVKAMVSFGQMFYPMLVSYMLLNNIWYGYGLIIPGILFVLITLML 184 + G A L+ ++V+ G+ P + M+ + I + Y L+IP I + + ++ Sbjct: 132 -IPKENRGKAFGLIGSIVAMGEGVGP-AIGGMIAHYIHWSYLLLIPMITIITVPFLM 186
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 119 bits (301), Expect = 3e-39 Identities = 34/89 (38%), Positives = 55/89 (61%) Query: 4 TKAEMSEYLFDKLGLSKRDAKELVELFFEEIRRALENGEQVKLSGFGNFDLRDKNQRPGR 63 K ++ + + L+K+D+ V+ F + L GE+V+L GFGNF++R++ R GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 64 NPKTGEDIPITARRVVTFRPGQKLKSRVE 92 NP+TGE+I I A +V F+ G+ LK V+ Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAVK 91
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 31.2 bits (71), Expect = 0.002 Identities = 14/61 (22%), Positives = 28/61 (45%), Gaps = 5/61 (8%) Query: 74 SNKAELTAIIARETGKPRWEAATEVTAMINKIAISIKAYHVRTGEQRSEMPDGAASLRHR 133 +NK +L A +A T + ++A V A+ + ++ + GE+ + G +R R Sbjct: 2 ANKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAK-----GEKVQLIGFGNFEVRER 56 Query: 134 P 134 Sbjct: 57 A 57
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 37.3 bits (86), Expect = 3e-05 Identities = 36/192 (18%), Positives = 56/192 (29%), Gaps = 58/192 (30%) Query: 2 PPRALLLV-DLQNDFCAGGALAVPEGDSTVDVANRLIDWCQSRGEAVI-----ASQD--- 52 P RA+LL+ D+QN F +L + C G V+ SQ+ Sbjct: 28 PNRAVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCVQLGIPVVYTAQPGSQNPDD 87 Query: 53 -------WHPANHGSFASQHGVEPYTPGQLDGLPQTFWPDHCVQNSEGAQLHPLLHQKAI 105 W P + + + P D + T W Sbjct: 88 RALLTDFWGPGLNSGPYEEKIITELAPEDDDLV-LTKW---------------------- 124 Query: 106 AAVFHKGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDAL 165 YSAF +T+L + +R D+LI+ G+ T +A Sbjct: 125 -------------RYSAFK------RTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAF 165 Query: 166 QLGYKVNVITDG 177 K + D Sbjct: 166 MEDIKAFFVGDA 177
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 39.9 bits (93), Expect = 2e-05 Identities = 30/129 (23%), Positives = 50/129 (38%), Gaps = 1/129 (0%) Query: 65 ALMFGYFIGSLTGGFIGDYFGRRRAFRINLLIVGIAATGAAFVPDMY-WLIFFRFLMGTG 123 A M + IG+ G + D G +R ++I + + LI RF+ G G Sbjct: 57 AFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAG 116 Query: 124 MGALIMVGYASFTEFIPATVRGKWSARLSFVGNWSPMLSAAIGVVVIAFFSWQIMFLLGG 183 A + +IP RGK + + + AIG ++ + W + L+ Sbjct: 117 AAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPM 176 Query: 184 IGILLAWFL 192 I I+ FL Sbjct: 177 ITIITVPFL 185
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 31.0 bits (70), Expect = 0.011 Identities = 33/142 (23%), Positives = 48/142 (33%), Gaps = 23/142 (16%) Query: 71 MFLGALVGGIIGDKTGRRNAFILYEAIHIASMVVGAFSPNMDF-LIACRFVMGVGLGALL 129 +G V G + D+ G + + I+ V+G + LI RF+ G G A Sbjct: 62 FSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFP 121 Query: 130 VTLFAGFTEYMPGRNR----GTWSSRVSFIGNWSYPLCSLIAMGLTPLISA----EWNWR 181 + Y+P NR G S V+ + G+ P I +W Sbjct: 122 ALVMVVVARYIPKENRGKAFGLIGSIVA------------MGEGVGPAIGGMIAHYIHWS 169 Query: 182 VQLLIPAILSLIATALAWRYFP 203 LLIP I I T Sbjct: 170 YLLLIPMI--TIITVPFLMKLL 189
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 27.7 bits (61), Expect = 0.022 Identities = 18/61 (29%), Positives = 26/61 (42%) Query: 49 QGLSIGIIILTIGVMAPIASGTLPPSTLIHSFLNWKSLVAIAVGVIVSWLGGRGVTLMGS 108 Q +I L IG + + LPPS ++ N ++ A VS LG +TL G Sbjct: 174 QRSAIVDGGLHIGALQSLQPEDLPPSRVVLRDTNVTAVPASGAPAAVSVLGASELTLDGG 233 Query: 109 Q 109 Sbjct: 234 H 234
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 30.0 bits (67), Expect = 6e-04 Identities = 9/37 (24%), Positives = 17/37 (45%), Gaps = 5/37 (13%) Query: 4 LSWIIFGLIAGILAKWIMPG-----KDGGGFFMTILL 35 + I+ G I+G++ W+ K ++ ILL Sbjct: 163 AAIIMRGYISGLMENWLFAPQSFDLKKEARDYVAILL 199
>FLAGELLIN#Flagellin signature. Length = 507 Score = 163 bits (413), Expect = 1e-45 Identities = 177/418 (42%), Positives = 223/418 (53%), Gaps = 6/418 (1%) Query: 2 AQVINTNSLSLITQNNINKNQSALSSSIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 61 AQVINTNSLSL+TQNN+NK+QS+LSS+IERLSSGLRINSAKDDAAGQAIANRFTSNIKGL Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 TQAARNANDGISVAQTTEGALSEINNNLQRIRELTVQATTGTNSDSDLDSIQDEIKSRLD 121 TQA+RNANDGIS+AQTTEGAL+EINNNLQR+REL+VQAT GTNSDSDL SIQDEI+ RL+ Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 EIDRVSGQTQFNGVNVLSKDGSMKIQVGANDGETITIDLKKIDSDTLNLAGFNVNGKGSV 181 EIDRVS QTQFNGV VLS+D MKIQVGANDGETITIDL+KID +L L GFNVNG Sbjct: 121 EIDRVSNQTQFNGVKVLSQDNQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKEA 180 Query: 182 ANTAATSDDLKLAGFTKGTTDTNGVTAYTNTISNDKAKASDLLANITDGSVITGGGANAF 241 S + G+ N +++ + D + Sbjct: 181 TVGDLKSSFKNVTGYDTYAVGANKYRV---DVNSGAVVTDTTAPTVPDKVYVNAANGQLT 237 Query: 242 GVAAKNGYTYDAASKSYSFAADGADSAKTLSIINPNTGDSSQATVTIGGKEQKVNISQDG 301 A+N D + S A A +I GD+ + K +G Sbjct: 238 TDDAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGNG 297 Query: 302 KITAADDNATLYL---DKQGNLTKTNAGNDTAATWDGLISNSDSTGAVPVGVATTITITS 358 K++ + + L D +A ++ + + ++ Sbjct: 298 KVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSD 357 Query: 359 GTASGMSVQSAGAGIQTSTNSQILAGGAFAAKVSIEGGAATDILVASNGNITAADGNA 416 A+ + + + + AG T V++ N AA Sbjct: 358 LEANNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINEDAAAAKK 415 Score = 92.8 bits (230), Expect = 7e-22 Identities = 91/332 (27%), Positives = 125/332 (37%) Query: 338 SNSDSTGAVPVGVATTITITSGTASGMSVQSAGAGIQTSTNSQILAGGAFAAKVSIEGGA 397 ++T +T A G + V+ G Sbjct: 176 GPKEATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQ 235 Query: 398 ATDILVASNGNITAADGNALYLDATTGGFTTTAGGNTAASLDNLIANSKDATLTVTSGTG 457 T +N + A T T G Sbjct: 236 LTTDDAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDG 295 Query: 458 QNTVYSTTGSGAQFTSLAKVDTVNVTNAHVSAEGMANLTKSNFTIDMGGTGTVTYTVSNG 517 V +T ++A + + + N+ S + Sbjct: 296 NGKVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKL 355 Query: 518 DVKAAANADVYVEDGALSANATKDVTYFEQKNGAITNSTGGTIYETADGKLTTEATTASS 577 A NA ++ ++ A + +A A Sbjct: 356 SDLEANNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINEDAAAAKK 415 Query: 578 STADPLKALDEAISSIDKFRSSLGAVQNRLDSAVTNLNNTTTNLSEAQSRIQDADYATEV 637 STA+PL ++D A+S +D RSSLGA+QNR DSA+TNL NT TNL+ A+SRI+DADYATEV Sbjct: 416 STANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYATEV 475 Query: 638 SNMSKAQIIQQAGNSVLAKANQVPQQVLSLLQ 669 SNMSKAQI+QQAG SVLA+ANQVPQ VLSLL+ Sbjct: 476 SNMSKAQILQQAGTSVLAQANQVPQNVLSLLR 507
>TYPE3OMBPROT#Type III secretion system outer membrane B protein family signature. Length = 538 Score = 32.7 bits (74), Expect = 0.003 Identities = 24/72 (33%), Positives = 37/72 (51%), Gaps = 2/72 (2%) Query: 214 NGMEVSVAAQNAQLTVNNVAIENSSNTISDALENITLNLNDVTTGNQTLTITQDTSKAQT 273 N E +VAA+N + + A+ + +S AL T++L V+T LT T T ++ Sbjct: 236 NSSERAVAARNKAEELVSAALYSRPELLSQALSGKTVDLKIVSTS--LLTPTSLTGGEES 293 Query: 274 AIKDWVNAYNSL 285 +KD VNA L Sbjct: 294 MLKDQVNALKGL 305
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.2 bits (68), Expect = 0.017 Identities = 10/57 (17%), Positives = 17/57 (29%), Gaps = 2/57 (3%) Query: 164 RFTLLPIFRIPVKMQKVSAASPLTQKPDQARRRF--RLGMLVFFGMLGWALLTAMNQ 218 R L R + + + A L + P R R M ++L + Sbjct: 26 RKQLDTPVREKDENEFLPAHLELIETPVSRRPRLVAYFIMGFLVIAFILSVLGQVEI 82
>PF01206#SirA family protein Length = 76 Score = 92.5 bits (230), Expect = 6e-29 Identities = 16/71 (22%), Positives = 37/71 (52%) Query: 7 DYRLDMVGEPCPYPAVATLEAMPQLKKGEILEVVSDCPQSINNIPLDARNHGYTVLDIQQ 66 D LD G CP P + + + + GE+L V++ P S+ + ++ G+ +L+ ++ Sbjct: 5 DQSLDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKE 64 Query: 67 DGPTIRYLIQK 77 + T + +++ Sbjct: 65 EDGTYHFRLKR 75
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 117 bits (294), Expect = 5e-38 Identities = 103/103 (100%), Positives = 103/103 (100%) Query: 2 SAIQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTL 61 SAIQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTL Sbjct: 1 SAIQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTL 60 Query: 62 GEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV 104 GEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV Sbjct: 61 GEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV 103
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 756 bits (1952), Expect = 0.0 Identities = 478/555 (86%), Positives = 514/555 (92%), Gaps = 5/555 (0%) Query: 3 ATAAQTKSLEWLNRLRANPKIPLIVAGSAAVAVMVALILWAKAPDYRTLFSNLSDQDGGA 62 +TA Q K LEWLNRLRANP+IPLIVAGSAAVA++VA++LWAK PDYRTLFSNLSDQDGGA Sbjct: 5 STATQPKPLEWLNRLRANPRIPLIVAGSAAVAIVVAMVLWAKTPDYRTLFSNLSDQDGGA 64 Query: 63 IVSQLTQMNIPYRFSEASGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQ 122 IV+QLTQMNIPYRF+ SGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQ Sbjct: 65 IVAQLTQMNIPYRFANGSGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQ 124 Query: 123 FSEQVNYQRALEGELSRTIETIGPVKGARVHLAMPKPSLFVREQKSPSASVTVNLLPGRA 182 FSEQVNYQRALEGEL+RTIET+GPVK ARVHLAMPKPSLFVREQKSPSASVTV L PGRA Sbjct: 125 FSEQVNYQRALEGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLEPGRA 184 Query: 183 LDEGQISAIVHLVSSAVAGLPPGNVTLVDQGGHLLTQFNTSGRDLNDAQLKYASDVEGRI 242 LDEGQISA+VHLVSSAVAGLPPGNVTLVDQ GHLLTQ NTSGRDLNDAQLK+A+DVE RI Sbjct: 185 LDEGQISAVVHLVSSAVAGLPPGNVTLVDQSGHLLTQSNTSGRDLNDAQLKFANDVESRI 244 Query: 243 QRRIEAILSPIVGNGNIHAQVTAQLDFASKEQTEEQYRPNGDESHAALRSRQLNESEQSG 302 QRRIEAILSPIVGNGN+HAQVTAQLDFA+KEQTEE Y PNGD S A LRSRQLN SEQ G Sbjct: 245 QRRIEAILSPIVGNGNVHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQVG 304 Query: 303 SGYPGGVPGALSNQPAPANNAPISTPPANQNNRQQ--QASTTSNS---GPRSTQRNETSN 357 +GYPGGVPGALSNQPAP N API+TPP NQ N Q Q ST++NS GPRSTQRNETSN Sbjct: 305 AGYPGGVPGALSNQPAPPNEAPIATPPTNQQNAQNTPQTSTSTNSNSAGPRSTQRNETSN 364 Query: 358 YEVDRTIRHTKMNVGDVQRLSVAVVVNYKTLPDGKPLPLSNEQMKQIEDLTREAMGFSEK 417 YEVDRTIRHTKMNVGD++RLSVAVVVNYKTL DGKPLPL+ +QMKQIEDLTREAMGFS+K Sbjct: 365 YEVDRTIRHTKMNVGDIERLSVAVVVNYKTLADGKPLPLTADQMKQIEDLTREAMGFSDK 424 Query: 418 RGDSLNVVNSPFNSSDESGGELPFWQQQAFIDQLLAAGRWLLVLLVAWLLWRKAVRPQLT 477 RGD+LNVVNSPF++ D +GGELPFWQQQ+FIDQLLAAGRWLLVL+VAW+LWRKAVRPQLT Sbjct: 425 RGDTLNVVNSPFSAVDNTGGELPFWQQQSFIDQLLAAGRWLLVLVVAWILWRKAVRPQLT 484 Query: 478 RRAEAMKAVQQQAQAREEVEDAVEVRLSKDEQLQQRRANQRLGAEVMSQRIREMSDNDPR 537 RR E KA Q+QAQ R+E E+AVEVRLSKDEQLQQRRANQRLGAEVMSQRIREMSDNDPR Sbjct: 485 RRVEEAKAAQEQAQVRQETEEAVEVRLSKDEQLQQRRANQRLGAEVMSQRIREMSDNDPR 544 Query: 538 VVALVIRQWINNDHE 552 VVALVIRQW++NDHE Sbjct: 545 VVALVIRQWMSNDHE 559
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 341 bits (876), Expect = e-119 Identities = 117/329 (35%), Positives = 197/329 (59%), Gaps = 2/329 (0%) Query: 1 MSNLTGTDKSVILLMTIGEDRAAEVFKHLSQREVQTLSAAMANVTQISNKQLTDVLAEFE 60 +S LTG K+ ILL++IG + +++VFK+LSQ E+++L+ +A + I+++ +VL EF+ Sbjct: 12 VSALTGKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKLETITSELKDNVLLEFK 71 Query: 61 QEAEQFAALNINANDYLRSVLVKALGEERAASLLEDILETRDTASGIETLNFMEPQSAAD 120 + + DY R +L K+LG ++A ++ + L + + E + +P + + Sbjct: 72 ELMMAQEFIQKGGIDYARELLEKSLGTQKAVDIINN-LGSALQSRPFEFVRRADPANILN 130 Query: 121 LIRDEHPQIIATILVHLKRAQAADILALFDERLRHDVMLRIATFGGVQPAALAELTEVLN 180 I+ EHPQ IA IL +L +A+ IL+ ++ +V RIA P + E+ VL Sbjct: 131 FIQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVVREVERVLE 190 Query: 181 GLLDGQ-NLKRSKMGGVRTAAEIINLMKTQQEEAVITAVREFDGELAQKIIDEMFLFENL 239 L + + GGV EIIN+ + E+ +I ++ E D ELA++I +MF+FE++ Sbjct: 191 KKLASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPELAEEIKKKMFVFEDI 250 Query: 240 VDVDDRSIQRLLQEVDSESLLIALKGAEQPLREKFLRNMSQRAADILRDDLANRGPVRLS 299 V +DDRSIQR+L+E+D + L ALK + P++EK +NMS+RAA +L++D+ GP R Sbjct: 251 VLLDDRSIQRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRAASMLKEDMEFLGPTRRK 310 Query: 300 QVENEQKAILLIVRRLAETGEMVIGSGED 328 VE Q+ I+ ++R+L E GE+VI G + Sbjct: 311 DVEESQQKIVSLIRKLEEQGEIVISRGGE 339
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 373 bits (959), Expect = e-135 Identities = 226/228 (99%), Positives = 228/228 (100%) Query: 1 MSDNLPWKTWTPDDLAPPQAEFVPMVEPEETIIEEAEPSLEQQLAQLQMQAHEQGYQAGI 60 MSDNLPWKTWTPDDLAPPQAEFVP+VEPEETIIEEAEPSLEQQLAQLQMQAHEQGYQAGI Sbjct: 1 MSDNLPWKTWTPDDLAPPQAEFVPIVEPEETIIEEAEPSLEQQLAQLQMQAHEQGYQAGI 60 Query: 61 AEGRQQGHEQGYQEGLAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRL 120 AEGRQQGH+QGYQEGLAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRL Sbjct: 61 AEGRQQGHKQGYQEGLAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRL 120 Query: 121 MQMALEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGAT 180 MQMALEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGAT Sbjct: 121 MQMALEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGAT 180 Query: 181 LSLHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQELCRLAAPGVV 228 LSLHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQELCRLAAPGVV Sbjct: 181 LSLHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQELCRLAAPGVV 228
>FLGFLIJ#Flagellar FliJ protein signature. Length = 147 Score = 202 bits (515), Expect = 2e-70 Identities = 146/147 (99%), Positives = 147/147 (100%) Query: 1 MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAG 60 MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAG Sbjct: 1 MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAG 60 Query: 61 MTSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQST 120 +TSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQST Sbjct: 61 ITSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQST 120 Query: 121 AALLAENRLDQKKMDEFAQRAAMRKPE 147 AALLAENRLDQKKMDEFAQRAAMRKPE Sbjct: 121 AALLAENRLDQKKMDEFAQRAAMRKPE 147
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 461 bits (1186), Expect = e-165 Identities = 361/375 (96%), Positives = 366/375 (97%) Query: 1 MIRLAPLITADVDTTTLPGGKASDAAQDFLALLSEALAGETTTDKAAPQLLVATDKPTTK 60 MIRLAPLITADVDTTTLPGGKASDAAQDFLALLSEALAGETTTDKAAPQLLVATDKPTTK Sbjct: 1 MIRLAPLITADVDTTTLPGGKASDAAQDFLALLSEALAGETTTDKAAPQLLVATDKPTTK 60 Query: 61 GEPLVSEILADAQQADLLIPVDETPPVINDEQSTSTPLTTAQTMTLAAVAGNNTAKDEKA 120 GEPL+S+I++DAQQA+LLIPVDETPPVINDEQSTSTPLTTAQTM LAAVA NT KDEKA Sbjct: 61 GEPLISDIVSDAQQANLLIPVDETPPVINDEQSTSTPLTTAQTMALAAVADKNTTKDEKA 120 Query: 121 DDLNEDVTASLSALFAMLPGFDNTPKVTDVPSTVLPAEKPTLFTKLTSAQLTTAQPDDAP 180 DDLNEDVTASLSALFAMLPGFDNTPKVTD PSTVLP EKPTLFTKLTS QLTTAQPDDAP Sbjct: 121 DDLNEDVTASLSALFAMLPGFDNTPKVTDAPSTVLPTEKPTLFTKLTSEQLTTAQPDDAP 180 Query: 181 GTPAQPLTPLVAEAQSKAEVISTPSPVTAAASPLITPHQTQPLPTVAAPVLSAPLGSHEW 240 GTPAQPLTPLVAEAQSKAEVISTPSPVTAAASPLITPHQTQPLPTVAAPVLSAPLGSHEW Sbjct: 181 GTPAQPLTPLVAEAQSKAEVISTPSPVTAAASPLITPHQTQPLPTVAAPVLSAPLGSHEW 240 Query: 241 QQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMVSPHQHVRAALEAA 300 QQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMVSPHQHVRAALEAA Sbjct: 241 QQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMVSPHQHVRAALEAA 300 Query: 301 LPVLRTQLAESGIQLGQSNISGESFSGQQQAASQQQQSQRTANHEPLAGEDDDTLPVPVS 360 LPVLRTQLAESGIQLGQSNISGESFSGQQQAASQQQQSQRTANHEPLAGEDDDTLPVPVS Sbjct: 301 LPVLRTQLAESGIQLGQSNISGESFSGQQQAASQQQQSQRTANHEPLAGEDDDTLPVPVS 360 Query: 361 LQVRVTGNSSVDIFA 375 LQ RVTGNS VDIFA Sbjct: 361 LQGRVTGNSGVDIFA 375
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 381 bits (979), Expect = e-135 Identities = 85/324 (26%), Positives = 148/324 (45%), Gaps = 10/324 (3%) Query: 5 ILSQAEIDALLNGDS--EVKDEPTASVSGESDIRPYDPNTQRRVVRERLQALEIINERFA 62 +LSQ EID LL S + E +S I YD + +E+++ L +++E FA Sbjct: 4 VLSQDEIDQLLTAISSGDASIEDARPISDTRKITLYDFRRPDKFSKEQMRTLSLMHETFA 63 Query: 63 RHFRMGLFNLLRRSPDITVGAIRIQPYHEFARNLPVPTNLNLIHLKPLRGTGLVVFSPSL 122 R L LR + V ++ Y EF R++P P+ L +I + PL+G ++ PS+ Sbjct: 64 RLTTTSLSAQLRSMVHVHVASVDQLTYEEFIRSIPTPSTLAVITMDPLKGNAVLEVDPSI 123 Query: 123 VFIAVDNLFGGDGRFPTKVEGREFTHTEQRVINRMLKLALEGYSDAWKAINPLEVEYVRS 182 F +D LFGG G+ KV+ R+ T E V+ ++ L ++W + L + Sbjct: 124 TFSIIDRLFGGTGQ-AAKVQ-RDLTDIENSVMEGVIVRILANVRESWTQVIDLRPRLGQI 181 Query: 183 EMQVKFTNITTSPNDIVVNTPFHVEIGNLTGEFNICLPFSMIEPLRELLVNPPLENS--R 240 E +F I P+++VV ++G G N C+P+ IEP+ L + +S R Sbjct: 182 ETNPQFAQI-VPPSEMVVLVTLETKVGEEEGMMNFCIPYITIEPIISKLSSQFWFSSVRR 240 Query: 241 NEDQNWRDNLVRQVQHSQLELVANFADISLRLSQILKLKPGDVLPIEKP---DRIIAHVD 297 + + L ++ +++VA + L + IL L+ GD++ + D + + Sbjct: 241 SSTTQYMGVLRDKLSTVDMDVVAEVGSLRLSVRDILGLRVGDIIRLHDTHVGDPFVLSIG 300 Query: 298 GVPVLTSQYGTLNGQYALRIEHLI 321 Q G + + A +I I Sbjct: 301 NRKKFLCQPGVVGKKIAAQILERI 324
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 212 bits (542), Expect = 1e-74 Identities = 125/137 (91%), Positives = 134/137 (97%) Query: 1 MSDMNNPADDNNGAMDDLWAEALSEQKSTSSKSAADAVFQQFGGGDVSGTLQDIDLIMDI 60 MSDMNNP+D+N GA+DDLWA+AL+EQK+T++KSAADAVFQQ GGGDVSG +QDIDLIMDI Sbjct: 1 MSDMNNPSDENTGALDDLWADALNEQKATTTKSAADAVFQQLGGGDVSGAMQDIDLIMDI 60 Query: 61 PVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGV 120 PVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGV Sbjct: 61 PVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGV 120 Query: 121 RITDIITPSERMRRLSR 137 RITDIITPSERMRRLSR Sbjct: 121 RITDIITPSERMRRLSR 137
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 334 bits (857), Expect = e-119 Identities = 244/245 (99%), Positives = 245/245 (100%) Query: 1 MRRLLSVAPVLLWLVTPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLM 60 MRRLLSVAPVLLWL+TPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLM Sbjct: 1 MRRLLSVAPVLLWLITPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLM 60 Query: 61 MTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEK 120 MTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEK Sbjct: 61 MTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEK 120 Query: 121 ISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELK 180 ISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELK Sbjct: 121 ISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELK 180 Query: 181 TAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLA 240 TAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLA Sbjct: 181 TAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLA 240 Query: 241 QSFYS 245 QSFYS Sbjct: 241 QSFYS 245
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 67.1 bits (164), Expect = 1e-18 Identities = 22/78 (28%), Positives = 42/78 (53%) Query: 4 ESVMMMGTEAMKVALALAAPLLLVALVTGLIISILQAATQINEMTLSFIPKIIAVFIAII 63 + ++ G +A+ + L L+ +VA + GL++ + Q TQ+ E TL F K++ V + + Sbjct: 2 DDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLF 61 Query: 64 IAGPWMLNLLLDYVRTLF 81 + W +LL Y R + Sbjct: 62 LLSGWYGEVLLSYGRQVI 79
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 202 bits (516), Expect = 6e-67 Identities = 256/261 (98%), Positives = 259/261 (99%) Query: 1 MMQVTSDQWLSWLSLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPA 60 M+QVTS+QWLSWL+LYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPA Sbjct: 1 MLQVTSEQWLSWLNLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPA 60 Query: 61 NDVPVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPGSHL 120 NDVPVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDP SHL Sbjct: 61 NDVPVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHL 120 Query: 121 NMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGSEPLNSNAFLALTKAGSLIF 180 NMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIG EPLNSNAFLALTKAGSLIF Sbjct: 121 NMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLIF 180 Query: 181 LNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFC 240 LNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFC Sbjct: 181 LNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFC 240 Query: 241 EHLFSEIFNLLADIISELPLI 261 EHLFSEIFNLLADIISELPLI Sbjct: 241 EHLFSEIFNLLADIISELPLI 261
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.045 Identities = 20/62 (32%), Positives = 29/62 (46%), Gaps = 15/62 (24%) Query: 320 AKYILTPVLWKYLYRYAKKHQARGNGFGYGMVYPNNPQSVTRTLSARYYKDGAEILIDRG 379 A+Y + PVLW Y+ R+ K + G+ VY +R +DG+E RG Sbjct: 166 ARYQVGPVLWGYVVRFIK---SDGDKLTLPYVY------------SRSQRDGSEAWKWRG 210 Query: 380 WD 381 WD Sbjct: 211 WD 212
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 34.4 bits (79), Expect = 3e-04 Identities = 22/92 (23%), Positives = 35/92 (38%), Gaps = 9/92 (9%) Query: 37 AQKLAADDDVDMLVILTACYFHDIVTLAKNHPQRQRSSILAAEETRRLLREEFVQFPA-- 94 +KLA + + D+ +ILT + L + Q + EE R+ E F A Sbjct: 219 GEKLAEEVNADIFMILTDV---NGAALYYGTEKEQWLREVKVEELRKYYEEG--HFKAGS 273 Query: 95 --EKIEAVCHAIAAHSFSAQIAPLTTEAKIVQ 124 K+ A I A IA L + ++ Sbjct: 274 MGPKVLAAIRFIEWGGERAIIAHLEKAVEALE 305
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 540 bits (1393), Expect = 0.0 Identities = 264/399 (66%), Positives = 307/399 (76%), Gaps = 22/399 (5%) Query: 1 MKRKVLAMLVPALLVAGAANAAEVYNKDGNKLDLYGKVAGLHYFSDDAGSDGDKSYARIG 60 MKRKVLA+++PALL AGAA+AAE+YNKDGNKLDLYGKV GLHYFSDD+ DGD++Y R+G Sbjct: 1 MKRKVLALVIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSDDSSKDGDQTYMRVG 60 Query: 61 FKGETQIADQFTGYGQWEFNIGANGTESDKGNTATRLAFAGLGFGQNGTFDYGRNYGVVY 120 FKGETQI DQ TGYGQWE+N+ AN TE + N+ TRLAFAGL FG G+FDYGRNYGV+Y Sbjct: 61 FKGETQINDQLTGYGQWEYNVQANTTEGEGANSWTRLAFAGLKFGDYGSFDYGRNYGVLY 120 Query: 121 DVEAWTDMLPEFGGDTYAGADNFMNGRANGVATYRNNGFFGQVDGLNFALQYQSNNEN-S 179 DVE WTDMLPEFGGD+Y ADN+M GRANGVATYRN FFG VDGLNFALQYQ NE+ S Sbjct: 121 DVEGWTDMLPEFGGDSYTYADNYMTGRANGVATYRNTDFFGLVDGLNFALQYQGKNESQS 180 Query: 180 GGLFGQEGSGKGKGRDIAQENGDGFGMSTSYDFDFGLSLGAAYSNSDRTDNQVHKGWHNT 239 + + G DI +NGDGFG+ST+YD G S GAAY+ SDRT+ QV Sbjct: 181 ADDVNIGTNNRNNGDDIRYDNGDGFGISTTYDIGMGFSAGAAYTTSDRTNEQV------- 233 Query: 240 RDGDRSDTTAGGETAEAWTVGAKYDANNVYLAAMYAETRNMTGYGKVDA-----IANKTQ 294 + T AGG+ A+AWT G KYDANN+YLA MY+ETRNMT YGK D +ANKTQ Sbjct: 234 ---NAGGTIAGGDKADAWTAGLKYDANNIYLATMYSETRNMTPYGKTDKGYDGGVANKTQ 290 Query: 295 NFEVVAQYQFDFGLRPSIAYLQSKGKDLGGWAHDGNGDPRYTNKDLVKYVDIGATYYFNK 354 NFEV AQYQFDFGLRP++++L SKGKDL + +KDLVKY D+GATYYFNK Sbjct: 291 NFEVTAQYQFDFGLRPAVSFLMSKGKDLTY------NNVNGDDKDLVKYADVGATYYFNK 344 Query: 355 NMSTYVDYKINLLDNDDDFYKENGIATDDIVAVGLVYQF 393 N STYVDYKINLLD+DD FYK+ GI+TDDIVA+G+VYQF Sbjct: 345 NFSTYVDYKINLLDDDDPFYKDAGISTDDIVALGMVYQF 383
>PF06580#Sensor histidine kinase Length = 349 Score = 37.5 bits (87), Expect = 7e-05 Identities = 29/147 (19%), Positives = 58/147 (39%), Gaps = 21/147 (14%) Query: 308 DTLSLNKEVENLLDYL--EYLSDEKEIRFKVECNQQIFADKI---LLQRMLSNLIVNAIR 362 +SL E+ + YL + E ++F+ + N I ++ L+Q ++ N I + I Sbjct: 214 RQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGIA 273 Query: 363 YSPEKSRIHITSFLDANGSLNIDIASPGTKINEPEKLFRRFWRGDNSRHSVGQGLGLSLV 422 P+ +I + D NG++ +++ + G+ + K G GL V Sbjct: 274 QLPQGGKILLKGTKD-NGTVTLEVENTGSLALKNTKE--------------STGTGLQNV 318 Query: 423 KA-IAELHGGSATYHYLSKHNVFRITL 448 + + L+G A K + Sbjct: 319 RERLQMLYGTEAQIKLSEKQGKVNAMV 345
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 84.5 bits (209), Expect = 9e-21 Identities = 30/117 (25%), Positives = 60/117 (51%), Gaps = 1/117 (0%) Query: 39 KILLIEDNQRTQEWVTQGLSEAGYVIDAVSDGRDGLYLALKDDYALIILDIMLPGMDGWQ 98 IL+ +D+ + + Q LS AGY + S+ D L++ D+++P + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 99 ILQTLRTA-KQTPVICLTARDSVDDRVRGLDSGANDYLVKPFSFSELLARVRAQLRQ 154 +L ++ A PV+ ++A+++ ++ + GA DYL KPF +EL+ + L + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 51.2 bits (122), Expect = 2e-08 Identities = 22/70 (31%), Positives = 44/70 (62%) Query: 22 QQLRERLIQELNLTPQQLHEESNLIQAGLDSIRLMRWLHWFRKNGYRLTLRELYAAPTLA 81 + +R+++ + L TP+ + ++ +L+ GLDS+R+M + +R+ G +T EL PT+ Sbjct: 233 ENIRKQIAELLQETPEDITDQEDLLDRGLDSVRIMTLVEQWRREGAEVTFVELAERPTIE 292 Query: 82 AWNQLMLSRS 91 W +L+ +RS Sbjct: 293 EWQKLLTTRS 302
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 45.8 bits (108), Expect = 1e-06 Identities = 32/156 (20%), Positives = 55/156 (35%), Gaps = 19/156 (12%) Query: 1561 LVTGAFGGLGRLAVNWLREKGARRIALLAPRVDESWLRDVEGGQTRVCR------CDVGD 1614 +TGA G+G L +GA + A + L V R DV D Sbjct: 12 FITGAAQGIGEAVARTLASQGAH---IAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 1615 AGQLATVLDDLAAN-GGIAGAIHAAGVLADAPLQELDDHQLAAVFAVKAQAASQLLQTLR 1673 + + + + G I ++ AGVL + L D + A F+V + +++ Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 1674 NH-----DGRYLILYSSAAAT----LGAPGQSAHAL 1700 + G + + S+ A + A S A Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAA 164
>INTIMIN#Intimin signature. Length = 939 Score = 73.2 bits (179), Expect = 9e-18 Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 3/60 (5%) Query: 86 QQIASTSQLIGSLLAEDMNSEQAANIARGWASSQASGVMTDWLSRFGTARITLGVNEDFS 145 QQ AS + S +N + A + A G A +QAS + WL +GTA + L +F Sbjct: 168 QQAASLGSQLQS---RSLNGDYAKDTALGIAGNQASSQLQAWLQHYGTAEVNLQSGNNFD 224
>INTIMIN#Intimin signature. Length = 939 Score = 56.6 bits (136), Expect = 1e-10 Identities = 61/263 (23%), Positives = 90/263 (34%), Gaps = 20/263 (7%) Query: 175 IAVKAHVNDQFGNPVTHQPATFSAAPSSQMIISQNTVSTNTQGVAEVTMTPERNGSYTVK 234 I A V G + P +F+ S ++S N+ +TN G A VT+ ++ G V Sbjct: 578 ITYTATVKKN-GVAQANVPVSFNIV-SGTAVLSANSANTNGSGKATVTLKSDKPGQVVVS 635 Query: 235 ASLANGASLEKQLEAI---DEKLTLTSSPLIGVNAPKGATLTATLT---SANGTPVEGQV 288 A A S I K ++T A T T PV Q Sbjct: 636 AKTAEMTSALNANAVIFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKGDKPVSNQE 695 Query: 289 INFSVTPEGATLSGGKVRTNSSGQAPVVLTSNKVGTYTVTASFHNGVTIQTQTTVKVTGN 348 + F+ T LS +T+++G A V LTS G V+A + V+ Sbjct: 696 VTFTTT--LGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTT 753 Query: 349 PSTTHVASFIADPSTIAATNSDLSTLKATVEDGSGNL-IEGLTVYFALKSGSTTLTSLTA 407 + I T ++ G NL G + +S + + S Sbjct: 754 LTID------DGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPAIAS--- 804 Query: 408 VTDQNGIATTSVKGEITGSVTVS 430 V +G T KG T SV S Sbjct: 805 VDASSGQVTLKEKGTTTISVISS 827 Score = 52.8 bits (126), Expect = 3e-09 Identities = 45/169 (26%), Positives = 62/169 (36%), Gaps = 5/169 (2%) Query: 271 TLTATLTSANGTPVEGQVINFSVTPEGATLSGGKVRTNSSGQAPVVLTSNKVGTYTVTAS 330 T TAT+ NG ++F++ A LS TN SG+A V L S+K G V+A Sbjct: 579 TYTATVKK-NGVAQANVPVSFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAK 637 Query: 331 FHNGVTIQTQTTVKVTGNPSTTHVASFIADPSTIAATNSDLSTLKATVEDGSGNLIEGLT 390 + V + AD +T A D T V G + Sbjct: 638 TAEMTSALNANAVIFVDQTKASI-TEIKADKTTAVANGQDAITYTVKVMKG-DKPVSNQE 695 Query: 391 VYFALKSGSTTLTSLTAVTDQNGIATTSVKGEITGSVTVSAVTSAGGMQ 439 V F G + + T TD NG A ++ G VSA S + Sbjct: 696 VTFTTTLGKLSNS--TEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVD 742 Score = 51.2 bits (122), Expect = 8e-09 Identities = 39/139 (28%), Positives = 59/139 (42%), Gaps = 3/139 (2%) Query: 13 AVTDADGKAKVTLKGTKAGAHTVTASMVGGKS--EQLVVNFTADTLTAQVNLNVTEDNFI 70 A T+ GKA VTLK K G V+A S V F T + + + + Sbjct: 612 ANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQTKASITEIKADKTTAV 671 Query: 71 ANNIGMTRLQATVTDGNGNPVEGIKVNFRGTSVTLSSTSVETDDQVFAEILVTSTEVGLK 130 AN V PV +V F T LS+++ +TD +A++ +TST G Sbjct: 672 ANGQDAITYTVKVMK-GDKPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKS 730 Query: 131 TVSASLADKPTEVISRLLN 149 VSA ++D +V + + Sbjct: 731 LVSARVSDVAVDVKAPEVE 749 Score = 39.7 bits (92), Expect = 2e-05 Identities = 35/213 (16%), Positives = 63/213 (29%), Gaps = 18/213 (8%) Query: 4 NFTLSDGDKAVTDADGKAKVTLKGTKAGAHTVTASMVGGKSE--QLVVNFTADTLTAQVN 61 TD +G AKVTL T G V+A + + V F N Sbjct: 701 TLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGN 760 Query: 62 LNVTEDNFIANNIGMTRLQATVTDGNGN-PVEGIKVNFRGTSVTLSSTSVETDDQVFAEI 120 + + + + + G N G + S + SV+ Sbjct: 761 IEI-----VGTGVKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPAIASVDASSGQ---- 811 Query: 121 LVTSTEVGLKTVSASLADKPTEVISRLLNAKVDVNSATITSQEIPEGQVMVAQDIAVKAH 180 VT E G T+S +D T + + + ++ + V ++ Sbjct: 812 -VTLKEKGTTTISVISSDNQT--ATYTIATPNSLIVPNMSKRVTYNDAVNTCKNFGG--- 865 Query: 181 VNDQFGNPVTHQPATFSAAPSSQMIISQNTVST 213 N + + + AA + S T+ + Sbjct: 866 KLPSSQNELENVFKAWGAANKYEYYKSSQTIIS 898
>INTIMIN#Intimin signature. Length = 939 Score = 30.0 bits (67), Expect = 0.004 Identities = 23/129 (17%), Positives = 47/129 (36%), Gaps = 6/129 (4%) Query: 11 KISAIDYSQNINGDYKATVTGGGEGIATLIPVLNGVHQAGLSTTIEFISAETRPMTGTVS 70 K+S + NG K T+T G + + ++ V + +EF G + Sbjct: 704 KLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFF-TTLTIDDGNIE 762 Query: 71 VNGANLPTASFPSQGFTGAYYQLNNDNFAPGKTAADYSFSSSASWVGVDATGKVTFKNDG 130 + G + P+ L + G + ++ A ++G+VT K G Sbjct: 763 IVGTGV-KGKLPTVWLQYGQVNL---KASGGNGKYTWRSANPAIASVDASSGQVTLKEKG 818 Query: 131 DSNTVIITA 139 + T+ + + Sbjct: 819 -TTTISVIS 826
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 35.2 bits (81), Expect = 5e-04 Identities = 42/262 (16%), Positives = 99/262 (37%), Gaps = 24/262 (9%) Query: 79 LGGVIFGHFGDRLGRKRMLMLTVWMMGIATALIGILPSFSTIGWWAPILLVTLRAIQGFA 138 +G ++G D+LG KR+L+ + + + + + SF ++ L+ R IQG Sbjct: 64 IGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSL-------LIMARFIQGAG 116 Query: 139 VGGEWGGAALLSVESAPENKK----AFYSSGVQVGYGVGLLLSTGLVSLISMMTTDEQFL 194 ++ P+ + S V +G GVG + + I Sbjct: 117 AAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYI---------- 166 Query: 195 SWGWRIPFLFSIVLVLGALWVRNGMEESAEFEQQQHYQAAAKKRIPVIEALLRHPGAFLK 254 W L ++ ++ ++ +++ + + + ++ +L + Sbjct: 167 --HWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSIS 224 Query: 255 IIALRLCELLTMYIVTAFALNYSTQNMGLPRELFLNIGLLVGGLSCLTIPCFAWLADRFG 314 + + + L +++ + + GL + + IG+L GG+ T+ F + Sbjct: 225 FLIVSVLSFL-IFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMM 283 Query: 315 RRRVYITGALIGTLSAFPFFMA 336 + ++ A IG++ FP M+ Sbjct: 284 KDVHQLSTAEIGSVIIFPGTMS 305
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 32.3 bits (73), Expect = 0.010 Identities = 162/831 (19%), Positives = 253/831 (30%), Gaps = 125/831 (15%) Query: 38 IALSLAAVTSVPALAAD----TVVQAGETVSGGTLTNHDNQIVLGTANGMTISTG----- 88 +A++L A+ + PA AD ++V+ GE G + D V TA+G TI Sbjct: 19 LAMALGALGAAPAAHADWNNQSIVKTGERQHGIHIQGSDPGGVR-TASGTTIKVSGRQAQ 77 Query: 89 ---LEYGPDNEANTGGQWIQNGGIANNTTVTGGGLQRVNAGGSVSDTVISAGGGQSLQGQ 145 LE G +G ++++ G V AG V+D A G + Sbjct: 78 GILLENPAAELQFRNGSVTSSGQLSDDGIRRFLGTVTVKAGKLVADHATLANVGDTWDDD 137 Query: 146 AVNTTLNGGEQWVHEGGIA---TGTVINEKGWQAVKSGAVATDTVVNTGAEGGPDAENGD 202 + + G + G V E+G + D ++ GA E+ Sbjct: 138 GIALYVAGEQAQASIADSTLQGAGGVQIERGANVTVQRSAIVDGGLHIGALQSLQPEDLP 197 Query: 203 TGQTVYGDAVRTTINKNGRQIVAAEGTVNTTVVYAGGDQTVHGHALDTTLNGGYQYVHNG 262 + V D T V A G V + T+ G + G + Sbjct: 198 PSRVVLRDTNVTA--------VPASGAPAAVSVLGASELTLDGGHITGGRAAGVAAMQGA 249 Query: 263 GTASGTVVNSDGWQIIKEGGLADFTTVNQKGKLQVNAGGTATNVTLKQGGALVTSTAATV 322 G GG GG GGA+ Sbjct: 250 VVHLQRATIRRGDA--PAGGAV--------------PGGAV------PGGAVPGGFGPGG 287 Query: 323 TGSNRLGNFTVENGKADGVVLESGGRLDVLEGHSAEKTRVDDGGTLAVSAGGKA---TGV 379 G G + V+ + + +S L G +GG G Sbjct: 288 FGPVLDGWYGVDVSGSSVELAQSIVEAPELGAAIRVGR-----GARVTVSGGSLSAPHGN 342 Query: 380 TMTSGGALI---ADSGATV---EGTNASGKFSIDGISGQASGLLLENG----GSFTVNAG 429 + +GGA + ++ G +A GK + + + L L G G Sbjct: 343 VIETGGARRFAPQAAPLSITLQAGAHAQGKALLYRVLPEPVKLTLTGGADAQGDIVATEL 402 Query: 430 GQASNTTVGHRGTLMLAAGGSLSGRTQLSKGASMVLNGDVVSTGDIVNAGEIRFDNQTTP 489 T++G + LA+ +G T+ S+ N V T + N G +R + + Sbjct: 403 PSIPGTSIG-PLDVALASQARWTGATRAVDSLSID-NATWVMTDN-SNVGALRLASDGSV 459 Query: 490 DAVLSRAVAKGDSPVTFHKLTTSNLTGQGGTINMRVRLDGSNASDQLVINGGQATGKTWL 549 D + F LT + L G G M V D SD+LV+ A+G+ L Sbjct: 460 D------FQQPAEAGRFKVLTVNTLAGS-GLFRMNVFAD-LGLSDKLVVMQD-ASGQHRL 510 Query: 550 AFTNVGNSNLGVATTGQGIRVVDAQNGATTEEGAFALSRPLQAGAFNYTLNRDSDEDWYL 609 N G+ T + +V G+ + G + Y L + + W L Sbjct: 511 WVRNSGSEPASANT----LLLVQTPLGSAATFTLANKDGKVDIGTYRYRLAANGNGQWSL 566 Query: 610 RSENAYRAEVPLY-----------------------TSMLTQAMDYDRILAGSRSHQTGV 646 A A P L+ A + G T Sbjct: 567 VGAKAPPAPKPAPQPGPQPPQPPQPQPEAPAPQPPAGRELSAAANAAVNTGGVGLASTLW 626 Query: 647 NGENNSVRLSIQGGHLGHDNNGGIARGATPKSSGSYGFVRLEGDLLRTEVAGMSL----- 701 E+N++ + L D G RG + R +VAG L Sbjct: 627 YAESNALSKRLGELRLNPDAGGAWGRGFAQRQQLDNRAGR----RFDQKVAGFELGADHA 682 Query: 702 ---TTGVYGAAGHSSVDVKDDDGSRAGTVRDDAGSLGGYLNLTHTSSGLWADIVAQGTRH 758 G + G + D + G D+ +GGY SG + D + +R Sbjct: 683 VAVAGGRWHLGGLAGYTRGDRGFTGDGGGHTDSVHVGGYATYI-ADSGFYLDATLRASRL 741 Query: 759 SMKASSDNND-------FRARGWGWLGSLETGLPFSITDNLMLEPQLQYTW 802 +D +R G G SLE G F+ D LEPQ + Sbjct: 742 ENDFKVAGSDGYAVKGKYRTHGVGA--SLEAGRRFTHADGWFLEPQAELAV 790
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 53.6 bits (129), Expect = 2e-10 Identities = 38/163 (23%), Positives = 65/163 (39%), Gaps = 29/163 (17%) Query: 1 MKILLIGKNGQVGWELQRSLSTLGD-VVAVD----YFDKEL----------------CGD 39 MK L+ G G +G+ + + L G VV +D Y+D L D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 40 LTNLEGIAQTVRTVRPDVVVNAAAHTAVDKA-ESERELSDLLNDKGVAVL--AAESAKLG 96 L + EG+ + + V + AV + E+ +D N G + K+ Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYAD-SNLTGFLNILEGCRHNKIQ 119 Query: 97 ALMVHYSTDYVFDGAGSH--YRREDEATGPLNVYGETKRAGEL 137 L ++ S+ V+ G + +D P+++Y TK+A EL Sbjct: 120 HL-LYASSSSVY-GLNRKMPFSTDDSVDHPVSLYAATKKANEL 160
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 182 bits (463), Expect = 8e-57 Identities = 84/355 (23%), Positives = 147/355 (41%), Gaps = 46/355 (12%) Query: 1 MKILVTGGAGFIGSAVVRHIIENTRDEVRVVDCLT--YAGNL-ESLAPVAGSERYSFSQT 57 MK LVTG AGFIG V + ++E +V +D L Y +L ++ + + F + Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAG-HQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKI 59 Query: 58 DITDAAAVAAQFSEFRPDIVMHLAAESHVDRSIDGPTAFIQTNVIGTFTLLEAARHYWSG 117 D+ D + F+ + V V S++ P A+ +N+ G +LE RH Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHN--- 116 Query: 118 LGEEQKQAFRFHHISTDEVYGDLHGTDDLFTEETPYA-PSSPYSASKAGSDHLVRAWNRT 176 + + S+ VYG F+ + P S Y+A+K ++ + ++ Sbjct: 117 ------KIQHLLYASSSSVYGL--NRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHL 168 Query: 177 YGLPVVVTNCSNNYGPYHFPEKLIPLTILNALAGKPLPVYGNGEQIRDWLYVEDHARALY 236 YGLP YGP+ P+ + L GK + VY G+ RD+ Y++D A A+ Sbjct: 169 YGLPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAII 228 Query: 237 KV------------------ATEGKSGETYNIGGHNERKNIDVVRTICAILDKVVAQKPG 278 ++ A YNIG + + +D ++ + L A+K Sbjct: 229 RLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGI-EAKK-- 285 Query: 279 NITHFADLITFVTDRPGHDLRYAIDAAKIQRDLGWVPQETFESGIEKTVHWYLNN 333 + L +PG L + D + +G+ P+ T + G++ V+WY + Sbjct: 286 ---NMLPL------QPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDF 331
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 35.8 bits (82), Expect = 6e-04 Identities = 28/162 (17%), Positives = 55/162 (33%), Gaps = 14/162 (8%) Query: 241 LEKTLNSISNNYLAQNVARQAAQDAKSLEFLNQQLPKVRNDLDIAEDKLNQYRRQKDSVD 300 LEK L N A + + + L + + L+ A + + +++ Sbjct: 195 LEKALEGAMNFSTADSAKIKTLE--AEKAALAARKADLEKALEGAMNFSTADSAKIKTLE 252 Query: 301 LSLEAKSVLEQIVNVDNQLNELTFRESEISQLYTKEHPTYKALMEKRKTLQDEKAKLNER 360 + ++ + EL T + K L ++ L+ EKA L + Sbjct: 253 ---------AEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQ 303 Query: 361 VSAMPKTQQDILQLSRDVDSGQAVYMQLLNRQQELNIAKSSA 402 + +Q L RD+D+ + QL Q+L + Sbjct: 304 SQVLNANRQS---LRRDLDASREAKKQLEAEHQKLEEQNKIS 342
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 36.0 bits (83), Expect = 2e-04 Identities = 53/268 (19%), Positives = 89/268 (33%), Gaps = 17/268 (6%) Query: 29 LSKSGFSAGEIGWSYACTAIAAILSPILVGSITDRFFSAQKVLAVLMFAGALLMYFAAQQ 88 L S G A A+ ++G+++DRF ++ + ++ AGA + Y Sbjct: 35 LVHSNDVTAHYGILLALYALMQFACAPVLGALSDRF--GRRPVLLVSLAGAAVDYAI--- 89 Query: 89 TTFAGFFPLLLAYSLTYMPTIALTNSIAFANVPDVERDFPRIRVMGTIG-WIASGLACGF 147 A F +L + T A T ++A A + D+ R R G + G+ G Sbjct: 90 MATAPFLWVLYIGRIVAGITGA-TGAVAGAYIADITDGDERARHFGFMSACFGFGMVAG- 147 Query: 148 LPQILGY-ADISPTNIPLLITAGSSALLGVFAFFLPDTPPKSTGKMDIKVMLGLDALILL 206 P + G SP + P A + L + FL K + + L A Sbjct: 148 -PVLGGLMGGFSP-HAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRW 205 Query: 207 RDKN------FLVFFFCSFLFAMPLAFYYIFANGYLTEVGMKNATGWMTLGQFSEIFFML 260 VFF + +P A + IF G + + Sbjct: 206 ARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAM 265 Query: 261 ALPFFTKRFGIKKVLLLGLVTAAIRYGF 288 R G ++ L+LG++ Y Sbjct: 266 ITGPVAARLGERRALMLGMIADGTGYIL 293 Score = 31.7 bits (72), Expect = 0.006 Identities = 32/153 (20%), Positives = 52/153 (33%), Gaps = 20/153 (13%) Query: 253 FSEIFFMLALPFFTKRFGIKKVLLLGLVTAAIRYGFFIYGSADEYFTYALLFPGILLHGV 312 + L + RFG + VLL+ L AA+ Y +L+ G ++ G+ Sbjct: 54 LMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAP-----FLWVLYIGRIVAGI 108 Query: 313 SYDFYYVTAYIYVDKKAPVHMRTAAQGLITLCCQGFGSLLGYRLGGVMMEKMFAYQEPVN 372 + V D R G ++ C GFG + G LGG+M F+ P Sbjct: 109 TGATGAVAGAYIAD-ITDGDERARHFGFMS-ACFGFGMVAGPVLGGLMGG--FSPHAP-- 162 Query: 373 GLTFNWSGMWTFGAVMIAIIAVLFMIFFRESDN 405 + A + + + ES Sbjct: 163 ---------FFAAAALNGLNFLTGCFLLPESHK 186
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 26.4 bits (58), Expect = 0.029 Identities = 13/42 (30%), Positives = 21/42 (50%), Gaps = 1/42 (2%) Query: 6 KMLLGVLLLVTSAAWAAPATAGSTNTSGISKYE-LSSFIADF 46 ++L G LLL++S +WA ++K E L + DF Sbjct: 11 RVLTGTLLLLSSYSWAQELDWLPIPYVYVAKGESLRDLLTDF 52
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 718 bits (1855), Expect = 0.0 Identities = 243/843 (28%), Positives = 392/843 (46%), Gaps = 35/843 (4%) Query: 2 LRMTPLASAI---VALLLGIEAYAAEETFDTHFMIGGMKDQQVANIRL--DDNQPLPGQY 56 R+ + A +AE F+ F+ Q VA++ + + PG Y Sbjct: 21 HRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADD--PQAVADLSRFENGQELPPGTY 78 Query: 57 DIDIYVNKQWRGKYEIIVKDNPQET----CLSREVIKRLGIN-----SDNFASGKQCLTF 107 +DIY+N + ++ E CL+R + +G+N N + C+ Sbjct: 79 RVDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPL 138 Query: 108 EQLVQGGSYTWDIGVFRLDFSVPQAWVEELESGYVPPENWERGINAFYTSYYLSQYYSDY 167 ++ + D+G RL+ ++PQA++ GY+PPE W+ GINA +Y S Sbjct: 139 TSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQN 198 Query: 168 KASGNNKSTYVRFNSGLNLLGWQLHSDASFSKTNNNPGV-----WKSNTLYLERGFAQLL 222 + GN+ Y+ SGLN+ W+L + ++S +++ W+ +LER L Sbjct: 199 RIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLR 258 Query: 223 GTLRVGDMYTSSDIFDSVRFRGVRLFRDMQMLPNSKQNFTPRVQGIAQSNALVTIEQNGF 282 L +GD YT DIFD + FRG +L D MLP+S++ F P + GIA+ A VTI+QNG+ Sbjct: 259 SRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGY 318 Query: 283 VVYQKEVPPGPFAITDLQLAGGGADLDVSVKEADGSVTTYLVPYAAVPNMLQPGVSKYDF 342 +Y VPPGPF I D+ AG DL V++KEADGS + VPY++VP + + G ++Y Sbjct: 319 DIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSI 378 Query: 343 AAGRSHIEGASKQSE-FVQVGYQYGFNNLLTLYGGSMVANNYYAFTLGTGWNT-RIGAIS 400 AG A ++ F Q +G T+YGG+ +A+ Y AF G G N +GA+S Sbjct: 379 TAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALS 438 Query: 401 VDATKSHSKQDNGDVFDGQSYQIAYNKFVSQTSTRFGLAAWRYSSRDYRTFNDHVWANNK 460 VD T+++S + DGQS + YNK ++++ T L +RYS+ Y F D ++ Sbjct: 439 VDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMN 498 Query: 461 DNYRRDENDVYDI----ADYYQNDFGRKNSFSANMSQSLPEGWGSVSLSTLWRDYWGRSG 516 ++ V + DYY + ++ ++Q L ++ LS + YWG S Sbjct: 499 GYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGR-TSTLYLSGSHQTYWGTSN 557 Query: 517 SSKDYQLSYSNNWRRISYTLAASQAYDENHHE-EKRFNIFISIPFD--WGDDVTTPRRQI 573 + +Q + + I++TL+ S + ++ + ++IPF D + R Sbjct: 558 VDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHA 617 Query: 574 YMSNSTTFDDQGFASNNTGLSGTVGSRDQFNYGVNLSYQHQGN---ETTAGANLTWNAPV 630 S S + D G +N G+ GT+ + +Y V Y G+ +T A L + Sbjct: 618 SASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGY 677 Query: 631 ATVNGSYSQSSTYRQAGASVSGGIVAWSGGVNLANRLSETFAVMNAPGIKDAYVNGQKYR 690 N YS S +Q VSGG++A + GV L L++T ++ APG KDA V Q Sbjct: 678 GNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGV 737 Query: 691 TTNRNGVVVYDGMTPYRENHLMLDVSQSDSEAELRGNRKIAAPYRGAVVLVNFDTDQRKP 750 T+ G V T YREN + LD + +L P RGA+V F + Sbjct: 738 RTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKA-RVGI 796 Query: 751 WFIKALRADGQPLMFGYEVNDIHGHNIGVVGQGSQLFIRTNEVPPSVNVAIDKQQGLSCT 810 + L + +PL FG V + G+V Q+++ + V V +++ C Sbjct: 797 KLLMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCV 856 Query: 811 ITF 813 + Sbjct: 857 ANY 859
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.1 bits (156), Expect = 3e-14 Identities = 22/113 (19%), Positives = 47/113 (41%), Gaps = 2/113 (1%) Query: 9 VMIVDDHPLMRRGVRQLLELDPGFEVVAEAGDGASAIDLANRLDIDVILLDLNMKGMSGL 68 +++ DD +R + Q L G++V + A+ D D+++ D+ M + Sbjct: 6 ILVADDDAAIRTVLNQALS-RAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 69 DTLNALRRDGVTAQIIILTVSDASSDVFALIDAGADGYLLKDSDPEVLLEAIR 121 D L +++ +++++ + + GA YL K D L+ I Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 28.0 bits (62), Expect = 0.008 Identities = 12/31 (38%), Positives = 18/31 (58%), Gaps = 1/31 (3%) Query: 34 KHIVLWLGLALACLGLAMVLWLLVL-QNVPV 63 + I+ +L + L C LAM+ W + L N PV Sbjct: 15 RRILFYLLMLLFCQQLAMIFWRIGLPDNAPV 45
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 30.2 bits (68), Expect = 0.016 Identities = 19/124 (15%), Positives = 47/124 (37%), Gaps = 20/124 (16%) Query: 339 EMHNGKLTIVG-----RLDNLFFSGGEGIQPEEVERVIAAHPAVLQVFIVPVADKEF--- 390 E +G + G +++ + + ++++ + H +++ + + + ++ Sbjct: 19 ESKDGNVLAKGLAERIGINDSLLTHNANGEKIKIKKDMKDHKDAIKLVLDALVNSDYGVI 78 Query: 391 ---------GHRPVAVMEYDHESVDLSEWVKDKLARFQQPVRWLTLPPELKNGGIKISRQ 441 GHR V EY SV +++ V + + L P + GIK Q Sbjct: 79 KDMSEIDAVGHRVVHGGEYFTSSVLITDDVLKAITDC-IELAPLHNPANI--EGIKACTQ 135 Query: 442 ALKE 445 + + Sbjct: 136 IMPD 139
>AUTOINDCRSYN#Autoinducer synthesis protein signature. Length = 216 Score = 34.8 bits (80), Expect = 6e-05 Identities = 14/79 (17%), Positives = 32/79 (40%), Gaps = 12/79 (15%) Query: 1 MIEWQDLHHSELSVSQLYALLQLRCAVFV--------VEQNCPYQDIDGDDLTGDNRHIL 52 M+E D++H+ LS ++ L LR F + D + + ++ Sbjct: 1 MLEIFDVNHTLLSETKSGELFTLRKETFKDRLNWAVQCTDGMEFDQYDNN----NTTYLF 56 Query: 53 GWKNDELVAYARILKSDDD 71 G K++ ++ R +++ Sbjct: 57 GIKDNTVICSLRFIETKYP 75
>PERTACTIN#Pertactin signature. Length = 922 Score = 29.7 bits (66), Expect = 0.035 Identities = 31/125 (24%), Positives = 47/125 (37%), Gaps = 14/125 (11%) Query: 21 PQPENKESQQQQPSTPTEQQVLAAQQAAIKEAEQSAAAAKALAQQEVQQYSDKQALQGRL 80 PQP ++ + P P +++ AA AA+ A+ Y++ AL RL Sbjct: 598 PQPPQRQPEAPAPQPPAGRELSAAANAAVNTGGVGLASTLW--------YAESNALSKRL 649 Query: 81 QEAPTFARAAKAKATHIANPGTARYQQFDDNPVKQVAQNPLATFSLDVDTGSYANVRRFL 140 E A A G A+ QQ D+ ++ Q +A F L D R+ Sbjct: 650 GELRLNPDAGGAWGR-----GFAQRQQLDNRAGRRFDQK-VAGFELGADHAVAVAGGRWH 703 Query: 141 NQGLL 145 GL Sbjct: 704 LGGLA 708
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 29.9 bits (67), Expect = 0.007 Identities = 13/67 (19%), Positives = 27/67 (40%), Gaps = 3/67 (4%) Query: 90 NGISIEDQDFAANLFRVARKCLSTGRLDDALPLLQRATEQLPEVSEYWLALAIQYRRCKK 149 N IS + + L+ +A +G+ +DA + Q S ++L L + + Sbjct: 29 NEISSDTLE---QLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQ 85 Query: 150 TEAAAQA 156 + A + Sbjct: 86 YDLAIHS 92
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 407 bits (1048), Expect = e-148 Identities = 250/251 (99%), Positives = 250/251 (99%) Query: 1 MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWR 60 MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWR Sbjct: 1 MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWR 60 Query: 61 DYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGM 120 DYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGM Sbjct: 61 DYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGM 120 Query: 121 ANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMADGLYPVLSWLTWPM 180 ANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMAD LYPVLSWLTWPM Sbjct: 121 ANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMADALYPVLSWLTWPM 180 Query: 181 SVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKPQENPNAQA 240 SVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKPQENPNAQA Sbjct: 181 SVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKPQENPNAQA 240 Query: 241 IQDDLKDIDSE 251 IQDDLKDIDSE Sbjct: 241 IQDDLKDIDSE 251
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 121 bits (306), Expect = 4e-32 Identities = 92/404 (22%), Positives = 167/404 (41%), Gaps = 17/404 (4%) Query: 19 VTIALSLATFMQMLDSTISNVAIPTISGFLGASTDEGTWVITSFGVANAIAIPVTGRLAQ 78 + I L + +F +L+ + NV++P I+ WV T+F + +I V G+L+ Sbjct: 15 ILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSD 74 Query: 79 RIGELRLFLLSVTFFSLSSLMCSLS-TNLDVLIFFRVVQGLMAGPLIPLSQSLLLRNYPP 137 ++G RL L + S++ + + +LI R +QG A L ++ R P Sbjct: 75 QLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPK 134 Query: 138 EKRTFALALWSMTVIIAPICGPILGGYICDNFSWGWIFLINVPMGIIVLTLCLTLLKGRE 197 E R A L V + GP +GG I W +L+ +PM I+ L L +E Sbjct: 135 ENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKE 192 Query: 198 TETSPVKMNLPGLTLLVLGVGGLQIMLDKGRDLDWFNSSTIIILTVVSVISLISLVIWES 257 ++ G+ L+ +G+ + ML F +S I +VSV+S + V Sbjct: 193 VRIKG-HFDIKGIILMSVGI--VFFML--------FTTSYSISFLIVSVLSFLIFVKHIR 241 Query: 258 TSENPILDLSLFKSRNFTIGIVSITCAYLFYSGAIVLMPQLLQETMGYNAIWAGLAYAPI 317 +P +D L K+ F IG++ + +G + ++P ++++ + G Sbjct: 242 KVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFP 301 Query: 318 GIMPLLIS-PLIGRYGNKIDMRLLVTFSFLMYAVCYYWRSVTFMPTIDFTGIILPQFFQG 376 G M ++I + G ++ ++ +V + S T F II+ G Sbjct: 302 GTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGG 361 Query: 377 FAVACFFLPLTTISFSGLPDNKFANASSMSNFFRTLSGSVGTSL 420 + ++TI S L + S+ NF LS G ++ Sbjct: 362 LSFTK--TVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAI 403
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 78.3 bits (193), Expect = 6e-18 Identities = 62/412 (15%), Positives = 122/412 (29%), Gaps = 96/412 (23%) Query: 13 RRKYFSLLAVVLFIAFSGAYAYWSMELEDMISTDDAYVT-GNADPISAQVSGSVTVVNHK 71 RR ++ F+ + + ++E + + + G + I + V + K Sbjct: 55 RRPRLVAYFIMGFLVIAFILSVLG-QVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVK 113 Query: 72 DTNYVRQGDILVSLDKTDATIALNKA---------------------------------- 97 + VR+GD+L+ L A K Sbjct: 114 EGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDE 173 Query: 98 ------------------KNNLANIVRQTNKLYLQDKQYSAEVASARIQ---YQQSLEDY 136 K + Q + L + AE + + Y+ Sbjct: 174 PYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233 Query: 137 NRRV----PLAKQGVISKE----------TLEHTKDTLISSKAALNAAIQAYKANKALVM 182 R+ L + I+K + S + + I + K LV Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVT 293 Query: 183 N-------TPLNR-QPQVVEAADATKEAWLALKRTDIKSPVTGYIAQRSVQ-VGETVSPG 233 L + + + + + I++PV+ + Q V G V+ Sbjct: 294 QLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTA 353 Query: 234 QSLMAVVPARQ-MWVNANFKETQLTDVRIGQSVNIISDLYGENVVFHGRVTGINMGTGNA 292 ++LM +VP + V A + + + +GQ+ I + F G +G Sbjct: 354 ETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVE------AFPYTRYGYLVGK--- 404 Query: 293 FSLLPAQNATGNWIKIVQRVPVEVSLDPKELMEH----PLRIGLSMTATIDT 340 + + +V V +S++ L PL G+++TA I T Sbjct: 405 VKNINLDAIEDQRLGLVFNVI--ISIEENCLSTGNKNIPLSSGMAVTAEIKT 454
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 49.1 bits (117), Expect = 3e-09 Identities = 22/148 (14%), Positives = 53/148 (35%), Gaps = 31/148 (20%) Query: 4 IIIDDHPLAIAAIRNLLIKNDIEILAELTEGGSAVQRVETLKPDIVIIDVDIPGVNGIQV 63 ++ DD + L + ++ + + + + D+V+ DV +P N + Sbjct: 7 LVADDDAAIRTVLNQALSRAGYDVRIT-SNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 64 LETLRKRQYSGIIIIVSAKNDHFYGKHCADAGANGFVSKKEGMNNIIAAIEAAKNGYCYF 123 L ++K + ++++SA+N + AI+A++ G + Sbjct: 66 LPRIKKARPDLPVLVMSAQNT------------------------FMTAIKASEKGAYDY 101 Query: 124 ---PFSLNRFVGSLTSDQQKLDSLSKQE 148 PF L + + L ++ Sbjct: 102 LPKPFDLTE---LIGIIGRALAEPKRRP 126
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 79.9 bits (197), Expect = 2e-17 Identities = 30/105 (28%), Positives = 51/105 (48%) Query: 960 SILIADDHPTNRLLLKRQLNLLGYDVDEATDGVQALHKVSMQHYDLLITDVNMPNMDGFE 1019 +IL+ADD R +L + L+ GYDV ++ ++ DL++TDV MP+ + F+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 1020 LTRKLREQNSSLPIWGLTANAQANEREKGLSCGMNLCLFKPLTLD 1064 L ++++ LP+ ++A K G L KP L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLT 109
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 50.5 bits (121), Expect = 2e-09 Identities = 33/116 (28%), Positives = 50/116 (43%), Gaps = 9/116 (7%) Query: 63 VRDGIVWDFFGAVTIVRRHLD-TLEQQFGRRFSHAATSFPPGTDP---RISINVLESAGL 118 ++DG++ DFF +++ + F R P G R + AG Sbjct: 76 MKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGA 135 Query: 119 EVSHVLDEPTAVA---DLLQLDNAG--VVDIGGGTTGIAIVKKGKVTYSADEATGG 169 +++EP A A L + G VVDIGGGTT +A++ V YS+ GG Sbjct: 136 REVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNGVVYSSSVRIGG 191
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 28.5 bits (63), Expect = 0.020 Identities = 19/124 (15%), Positives = 40/124 (32%), Gaps = 6/124 (4%) Query: 34 QQGKNEEQRQHDEWVAERNREIQQEKQRRANAQAAANKRAATAAANKKARQDKLDAEASA 93 Q + ++ + + + E+ Q Q K AT +KA+ + + Sbjct: 1064 QNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVET-EKTQEV 1122 Query: 94 DKKRDQSYEDELRSLEIQKQKLALAKEEARVKRENEFIDQELKHKAAQTDVVQSEADANR 153 K Q + +S +Q Q + + V I + D Q + + Sbjct: 1123 PKVTSQVSPKQEQSETVQPQAEPARENDPTVN-----IKEPQSQTNTTADTEQPAKETSS 1177 Query: 154 NMTE 157 N+ + Sbjct: 1178 NVEQ 1181
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 114 bits (288), Expect = 5e-30 Identities = 81/371 (21%), Positives = 144/371 (38%), Gaps = 74/371 (19%) Query: 23 GIDLGTTNSLVATVRSGQAETLADHEGRHLLPSVVHYQQQGHS-------VGYDARTNAA 75 IDLGT N+L+ G + +E PSVV +Q VG+DA+ Sbjct: 14 SIDLGTANTLIYVKGQG----IVLNE-----PSVVAIRQDRAGSPKSVAAVGHDAK-QML 63 Query: 76 LDTANTISSVKRLMGRSLADIQQRYPHLPYQFQASENGLPMIETAAGLLNPVRVSADILK 135 T I++++ + +AD V+ +L+ Sbjct: 64 GRTPGNIAAIRPMKDGVIADF-------------------------------FVTEKMLQ 92 Query: 136 ALAARATEALAGE-LDGVVITVPAYFDDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYG 194 + V++ VP +R+ +++A+ AG + L+ EP AAAI G Sbjct: 93 HFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAG 152 Query: 195 LDSGQEGVIAVYDLGGGTFDISILRLSRGVFEVLATGGDSALGGDDFDHLLADYIREQAG 254 L + V D+GGGT +++++ L+ V +GGD FD + +Y+R G Sbjct: 153 LPVSEATGSMVVDIGGGTTEVAVISLNGVV-----YSSSVRIGGDRFDEAIINYVRRNYG 207 Query: 255 --IPDRSDNRVQRELLDAAIAAKIALSDADSVTVNVAG---WQG-----EISREQFNELI 304 I + + R++ E+ A + + V G +G ++ + E + Sbjct: 208 SLIGEATAERIKHEI-------GSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEAL 260 Query: 305 APLVKRTLLACRRALKDAGVE-ADEVLE--VVMVGGSTRVPLVRERVGEFFGRPPLTSID 361 + + A AL+ E A ++ E +V+ GG + + + E G P + + D Sbjct: 261 QEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAED 320 Query: 362 PDKVVAIGAAI 372 P VA G Sbjct: 321 PLTCVARGGGK 331
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 26.3 bits (58), Expect = 0.032 Identities = 23/87 (26%), Positives = 36/87 (41%), Gaps = 11/87 (12%) Query: 4 KTLTAAAAVLLMLTAGCSTLERVVYRPDINQGNYLTANDVSKIRV--GMTQQQVAYALGT 61 K + AVL + AG LER ++ Q + + + VS+ + GMT ++ A Sbjct: 69 KVV-LCGAVLARVDAGDEQLERKIH---YRQQDLVDYSPVSEKHLADGMTVGELCAA--A 122 Query: 62 PLMSDPFGTNTWFYVFRQQPGHEGVTQ 88 MSD N + G G+T Sbjct: 123 ITMSDNSAANL---LLATVGGPAGLTA 146
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 232 bits (593), Expect = 5e-65 Identities = 220/891 (24%), Positives = 344/891 (38%), Gaps = 103/891 (11%) Query: 722 NDGGTLDVREKGSATGIQQSSQGAL-VATTRATRVTGTRADGVAFSIEQGAANNILLANG 780 N+ + E+ IQ S G + A+ +V+G +A G+ + A + NG Sbjct: 37 NNQSIVKTGERQHGIHIQGSDPGGVRTASGTTIKVSGRQAQGILL---ENPAAELQFRNG 93 Query: 781 GVLT----VESDTSSDKTQVNMGGREIVKTKATATGTTLTGGEQ----IVEGVANETTIN 832 V + + V + ++V AT T + V G + +I Sbjct: 94 SVTSSGQLSDDGIRRFLGTVTVKAGKLVADHATLANVGDTWDDDGIALYVAGEQAQASIA 153 Query: 833 DGGIQTVSANGEAIKTKINEGGTLTVNDNGKATDIVQN--------SGAALQTSTANGIE 884 D +Q + + D G +Q+ S L+ + + Sbjct: 154 DSTLQGAGGVQIERGANVTVQR-SAIVDGGLHIGALQSLQPEDLPPSRVVLRDTNVTAVP 212 Query: 885 ISGTHQY------------GTFSISGNLATNMLLENGGNLLVLAGTEARDSTVG------ 926 SG G G A ++ L A D+ G Sbjct: 213 ASGAPAAVSVLGASELTLDGGHITGGRAAGVAAMQGAVVHLQRATIRRGDAPAGGAVPGG 272 Query: 927 --KGGAMQNLGQDSATKVNSGGQYTL---GRSKDEFQALARAEDLQVA-----GGTAIVY 976 GGA+ G Y + G S + Q++ A +L A G V Sbjct: 273 AVPGGAVPGGFGPGGFGPVLDGWYGVDVSGSSVELAQSIVEAPELGAAIRVGRGARVTVS 332 Query: 977 AGTLA--DASVSGATGSLSLMTPRDNVTPVKLEGAVRITDSA----------TLTLGNGV 1024 G+L+ +V G+ P+ + L+ A LTL G Sbjct: 333 GGSLSAPHGNVIETGGARRFA-PQAAPLSITLQAGAHAQGKALLYRVLPEPVKLTLTGGA 391 Query: 1025 DTTLADLTA----------ASRGSVWLNSNNSCAG---------------TSNCEYRVNS 1059 D D+ A V L S G V + Sbjct: 392 DA-QGDIVATELPSIPGTSIGPLDVALASQARWTGATRAVDSLSIDNATWVMTDNSNVGA 450 Query: 1060 LLLNDGDVYLSAQTAAPATTNGIYNTLTTNELSGSGNFYLHTNVAGSRGDQLVVNNNATG 1119 L L D + Q A A G + LT N L+GSG F ++ D+LVV +A+G Sbjct: 451 LRL-ASDGSVDFQQPAEA---GRFKVLTVNTLAGSGLFRMNVFADLGLSDKLVVMQDASG 506 Query: 1120 NFKIFVQDTGVSPQSDDAMTLVKT-GGGDASFTLGNTGGFVDLGTYEYVLKSDGNSNWNL 1178 +++V+++G P S + + LV+T G A+FTL N G VD+GTY Y L ++GN W+L Sbjct: 507 QHRLWVRNSGSEPASANTLLLVQTPLGSAATFTLANKDGKVDIGTYRYRLAANGNGQWSL 566 Query: 1179 TNDVKPNPDPIPNPKPDPKPDPKPDPNPKPDPTPDPTPTPVPEKRITPSTAAVLNMA--A 1236 P P PKP P+P P+P P+P P P P P + ++ + A +N Sbjct: 567 VGAKAP-----PAPKPAPQPGPQPPQPPQPQPEA-PAPQPPAGRELSAAANAAVNTGGVG 620 Query: 1237 TLPLVFDAELNSIRERLNIMKASPHNNNVWGATYNTRNNVTTDAGAGFEQTLTGMTVGID 1296 ++ AE N++ +RL ++ +P WG + R + AG F+Q + G +G D Sbjct: 621 LASTLWYAESNALSKRLGELRLNPDAGGAWGRGFAQRQQLDNRAGRRFDQKVAGFELGAD 680 Query: 1297 SRNDIPEGITTLGAFMGYSHSHIGFDRGGHGSVGSYSLGGYASWEHESGFYLDGVVKLNR 1356 + G LG GY+ GF G G S +GGYA++ +SGFYLD ++ +R Sbjct: 681 HAVAVAGGRWHLGGLAGYTRGDRGFTGDGGGHTDSVHVGGYATYIADSGFYLDATLRASR 740 Query: 1357 FKSNVAGKMSSGGAANGSYHSNGLGGHIETGMRFT-DGNWNLTPYASLTGFTADNPEYHL 1415 +++ S G A G Y ++G+G +E G RFT W L P A L F A Y Sbjct: 741 LENDFKVAGSDGYAVKGKYRTHGVGASLEAGRRFTHADGWFLEPQAELAVFRAGGGAYRA 800 Query: 1416 SNGMKSKSVDTRSIYRELGATLSYNMRLGNGMEVEPWLKAAVRKEFVDDNRVKVNSDGNF 1475 +NG++ + S+ LG + + L G +V+P++KA+V +EF V N + Sbjct: 801 ANGLRVRDEGGSSVLGRLGLEVGKRIELAGGRQVQPYIKASVLQEFDGAGTVHTNGIAHR 860 Query: 1476 VNYLSGRRGIYQAGIKASFSSTLSGHLGVGYSHSAGVESPWNAVAGVNWSF 1526 L G R G+ A+ S + YS + PW AG +S+ Sbjct: 861 TE-LRGTRAELGLGMAAALGRGHSLYASYEYSKGPKLAMPWTFHAGYRYSW 910
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 28.7 bits (64), Expect = 0.014 Identities = 20/105 (19%), Positives = 35/105 (33%), Gaps = 17/105 (16%) Query: 1 MKPRQRQAAILEYLQKQGKCSVEEL-----AQYFDTTGTTIRKDLVILEHAGTVIRTYGG 55 M QR I E + + +EL ++ T T+ +D+ E + T G Sbjct: 1 MNKGQRHIKIREIITANEIETQDELVDILKKDGYNVTQATVSRDIK--ELHLVKVPTNNG 58 Query: 56 ---VVLNKEESDPPIDHKTLINTHKKELIAEAAVSFIHDGDSIIL 97 L ++ P+ K + +A V I+L Sbjct: 59 SYKYSLPADQRFNPLS-------KLKRSLMDAFVKIDSASHLIVL 96
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 374 bits (961), Expect = e-127 Identities = 125/388 (32%), Positives = 196/388 (50%), Gaps = 33/388 (8%) Query: 149 IAALAAGALS----------NALLIEQLESQNMLPGDATPFEAVKQTQMIGLSPGMTQLK 198 I A GA +I + ++ ++ ++G S M ++ Sbjct: 91 IKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIY 150 Query: 199 KEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLVYLNCAALPESVAESELFG 258 + + + +DL ++I+GE+GTGKELVA+A+H+ R P V +N AA+P + ESELFG Sbjct: 151 RVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFG 210 Query: 259 HVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRCLR 318 H KGAFTGA + +G+FE A+ GTLFLDEIG++ + Q +LLRVLQ G+ VG +R Sbjct: 211 HEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIR 270 Query: 319 VDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRL 378 DVR++AATN+DL++ + G FR DL++RL+V PL +PPLR+R +D+ L +F +Q Sbjct: 271 SDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAE- 329 Query: 379 RQGLSRVVLSAGARNLLQHYSFPGNVRELEHAIHRAVVLARATRSGDEVIL-----EAQH 433 ++GL A L++ + +PGNVRELE+ + R L E+I E Sbjct: 330 KEGLDVKRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPD 389 Query: 434 FAFPEVTLPTPEVAAVPVVKQNLR-----------------EATEAFQRETIRQALAQNH 476 + + ++ V++N+R + I AL Sbjct: 390 SPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATR 449 Query: 477 HNWAACARMLETDVANLHRLAKRLGLKD 504 N A +L + L + + LG+ Sbjct: 450 GNQIKAADLLGLNRNTLRKKIRELGVSV 477
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 28.4 bits (63), Expect = 0.036 Identities = 17/93 (18%), Positives = 29/93 (31%), Gaps = 7/93 (7%) Query: 3 TTMLEVAKRAGVSKATVSRVLSG-----NGYVSQETKDRVFQAVEESGYRPNLLARNLSA 57 T++ E+AK AGV++ + + + +E P L Sbjct: 32 TSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPGDPLSVLRE 91 Query: 58 KSTQTLGLVVTNTLYHGIYFSELLFHAARMAEE 90 L VT + E++FH E Sbjct: 92 ILIHVLESTVTEERRRLLM--EIIFHKCEFVGE 122
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 29.5 bits (66), Expect = 0.029 Identities = 22/130 (16%), Positives = 40/130 (30%), Gaps = 16/130 (12%) Query: 261 SAPSWTQISRVVVDKIIQNENGNRVAAVVNQ-FRNIAPQSPLELIMGGYRNNQASILERR 319 +A QI + + + ++ VVN F + EL Q S +++ Sbjct: 404 TADQMKQIEDLTREAMGFSDKRGDTLNVVNSPFSAVDNTGG-ELPF----WQQQSFIDQ- 457 Query: 320 HDVLMFNQGWQQYGNVINEIVTVGLGYKTALRKALYTFAEGFKNKDFKGAGVSVHETAER 379 G + +V + ++ A+R L E K + E A Sbjct: 458 ---------LLAAGRWLLVLVVAWILWRKAVRPQLTRRVEEAKAAQEQAQVRQETEEAVE 508 Query: 380 HFYRQSELLI 389 + E L Sbjct: 509 VRLSKDEQLQ 518
>PF07675#Cleaved Adhesin Length = 1358 Score = 30.4 bits (68), Expect = 0.021 Identities = 20/92 (21%), Positives = 39/92 (42%), Gaps = 12/92 (13%) Query: 206 ILGQTYLPRKFKTTVVIP---PQND--IDLHANDMNFVAIAENGKLVGFNLLVGGGLSIE 260 ++ +P+ T +P PQN + A+ ++VAI+++G L G + G++ Sbjct: 240 VMPYRAMPKT--NTYTLPASLPQNQASYSIQASAGSYVAISKDGVLYGTGVANASGVATV 297 Query: 261 HGNK-----KTYARTASEFGYLPLEHTLAVAE 287 + K Y + YLP+ + E Sbjct: 298 NMTKQITENGNYDVVITRSNYLPVIKQIQAGE 329
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 35.2 bits (81), Expect = 4e-04 Identities = 45/314 (14%), Positives = 112/314 (35%), Gaps = 36/314 (11%) Query: 93 LGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTP-EHLIGLRILIGIGLGGDYSV 151 +G+ V G +SD +G +++ F ++ S + F + LI R + G G ++ Sbjct: 64 IGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPAL 123 Query: 152 GHTLLAEFSPRRHRGILLGAFSVVWT----VGYVLASIAGHHFISENPEAWRWLLASAAL 207 ++A + P+ +RG G + VG + + H+ W +LL + Sbjct: 124 VMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYI------HWSYLLLIPMI 177 Query: 208 PALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVVTATHKHIKTLF-- 265 + + L + R +G F I+ +L + + + L Sbjct: 178 TIITVPFLMKLLKKEVR---IKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFL 234 Query: 266 -SSRYWRRTA--------FNSVFFVCLVIPWFVIYT----WLPTIAQTIGLEDALTASLM 312 ++ R+ ++ F+ V+ +I+ ++ + + L+ + + Sbjct: 235 IFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEI 294 Query: 313 LNALLIVGALLGLV-------LTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLF 365 + ++ G + ++ L L L+ + + + L +S + + Sbjct: 295 GSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTII 354 Query: 366 VLFSTTISAVSNLV 379 ++F + + V Sbjct: 355 IVFVLGGLSFTKTV 368
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 102 bits (255), Expect = 4e-28 Identities = 73/257 (28%), Positives = 116/257 (45%), Gaps = 11/257 (4%) Query: 11 MDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANIFIPSFVKDNGETKEMIEK-QGVEVD 69 M+ ++GK A +TG G+G+A A LA GA+I + + E K + + Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE 60 Query: 70 FMQVGITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAA 129 + A +I A G +DILVN AG+ + + +W+ VN T Sbjct: 61 AFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGV 120 Query: 130 FELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNI 189 F S +K M+ ++SG I+ + S + + AY+++K A FTK EL +YNI Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNI 180 Query: 190 QVNGIAPGYYATDI--TLATRSNPETNQRVLDH-------IPANRWGDTQDLMGAAVFLA 240 + N ++PG TD+ +L N Q + IP + D+ A +FL Sbjct: 181 RCNIVSPGSTETDMQWSLWADENGAE-QVIKGSLETFKTGIPLKKLAKPSDIADAVLFLV 239 Query: 241 SPASNYVNGHLLVVDGG 257 S + ++ H L VDGG Sbjct: 240 SGQAGHITMHNLCVDGG 256
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 30.2 bits (68), Expect = 0.018 Identities = 22/103 (21%), Positives = 45/103 (43%), Gaps = 8/103 (7%) Query: 48 GLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVMLCIQIA 107 G++++ + + G ++D+F R ++ ++ + +MAT P LWV+ +I Sbjct: 46 GILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIV 105 Query: 108 FAITTILMLWSVSIKAASLLGD---HSEQGKIMGWMEGLRGVG 147 IT + A + + D E+ + G+M G G Sbjct: 106 AGITG-----ATGAVAGAYIADITDGDERARHFGFMSACFGFG 143
>cloacin#Cloacin signature. Length = 551 Score = 33.1 bits (75), Expect = 0.001 Identities = 15/36 (41%), Positives = 20/36 (55%) Query: 253 ASGRSYHSDNSGSAGGSDSGGFSGGGGSSGGGGASG 288 + G + S+N+ GGS SG GGG G GG +G Sbjct: 34 SDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNG 69 Score = 30.8 bits (69), Expect = 0.006 Identities = 11/34 (32%), Positives = 14/34 (41%) Query: 254 SGRSYHSDNSGSAGGSDSGGFSGGGGSSGGGGAS 287 SG H G G SGGG +GG ++ Sbjct: 50 SGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSA 83 Score = 30.1 bits (67), Expect = 0.012 Identities = 11/30 (36%), Positives = 11/30 (36%) Query: 259 HSDNSGSAGGSDSGGFSGGGGSSGGGGASG 288 GGS G G G S GG G G Sbjct: 50 SGSGIHWGGGSGHGNGGGNGNSGGGSGTGG 79 Score = 29.7 bits (66), Expect = 0.013 Identities = 12/34 (35%), Positives = 17/34 (50%), Gaps = 1/34 (2%) Query: 255 GRSYHSDNSGSAGGSDSGGFSGGGGSSGGGGASG 288 GR H+ + S G+ +GG +G G G SG Sbjct: 6 GRG-HNTGAHSTSGNINGGPTGLGVGGGASDGSG 38
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 29.3 bits (65), Expect = 0.038 Identities = 31/132 (23%), Positives = 51/132 (38%), Gaps = 9/132 (6%) Query: 211 GYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLA-----GEGN 265 P L N + A+ +E K YE+GK I+L + + ++ + + Sbjct: 147 RETPKLIINIKDYAINSEQSKEVYYEIGKGISLDIISKDKSLDPEFLNLIKSLSDDSDSS 206 Query: 266 KAFTSEEFTHFLEELTKQYPIVSIEDGLDESDW---DGFAYQTKVLG-DKIQLVGDDLFV 321 S++F LE K I I++ L E F+Y ++L D+F Sbjct: 207 DLLFSQKFKEKLELNNKSIDINFIKENLTEFQHAFSLAFSYYFAPDHRTVLELYAPDMFE 266 Query: 322 TNTKILKEGIEK 333 K+ K G EK Sbjct: 267 YMNKLEKGGFEK 278
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 55.7 bits (134), Expect = 2e-10 Identities = 39/167 (23%), Positives = 69/167 (41%), Gaps = 1/167 (0%) Query: 38 LDIGVIAGALPFITDHFVLTSRLQEWVVSSMMLGAAIGALFNGWLSFRLGRKYSLMAGAI 97 L+ V+ +LP I + F WV ++ ML +IG G LS +LG K L+ G I Sbjct: 28 LNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGII 87 Query: 98 LFVLGSIGSAFATS-VEMLIAARVVLGIAVGIASYTAPLYLSEMASENVRGKMISMYQLM 156 + GS+ S +LI AR + G + ++ + RGK + + Sbjct: 88 INCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSI 147 Query: 157 VTLGIVLAFLSDTAFSYSGNWRAMLGVLALPAVLLIILVVFLPNSPR 203 V +G + ++ +W +L + + + + L+ L R Sbjct: 148 VAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVR 194
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 111 bits (278), Expect = 1e-31 Identities = 72/257 (28%), Positives = 129/257 (50%), Gaps = 11/257 (4%) Query: 3 LSAFSLEGKVAVVTGCDTGLGQGMALGLAQAGCDIVGIN-IVEPTETIEQ-VTALGRRFL 60 ++A +EGK+A +TG G+G+ +A LA G I ++ E E + + A R Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE 60 Query: 61 SLTADLRKIDGIPALLDRAVAEFGHIDILVNNAGLIRREDALEFSEKDWDDVMNLNIKSV 120 + AD+R I + R E G IDILVN AG++R S+++W+ ++N V Sbjct: 61 AFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGV 120 Query: 121 FFMSQAAAKHFIAQGNGGKIINIASMLSFQGGIRVPSYTASKSGVMGVTRLMANEWAKHN 180 F S++ +K+ + + G I+ + S + + +Y +SK+ + T+ + E A++N Sbjct: 121 FNASRSVSKYMMDR-RSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYN 179 Query: 181 INVNAIAPGYMATNNTQQLRADEQRSAEILD--------RIPAGRWGLPSDLMGPIVFLA 232 I N ++PG T+ L ADE + +++ IP + PSD+ ++FL Sbjct: 180 IRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLV 239 Query: 233 SSASDYVNGYTIAVDGG 249 S + ++ + + VDGG Sbjct: 240 SGQAGHITMHNLCVDGG 256
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 70.7 bits (173), Expect = 4e-18 Identities = 28/164 (17%), Positives = 65/164 (39%), Gaps = 9/164 (5%) Query: 1 MSTETIEIFNNSDEWANQLKHALSKGENLALLHGLTPDILDRIYAYAFDYHEKGNITDAE 60 M ET + + E+ ++ L G +A+L+ ++ D L+++Y+ AF+ ++ G DA Sbjct: 1 MQQETTD----TQEYQLAMESFLKGGGTIAMLNEISSDTLEQLYSLAFNQYQSGKYEDAH 56 Query: 61 IYYKFLCIYAFENHEYLKDFASVCQPKKKYQQAYDLYKLSYNYFPYDDYSVIYRMGQCQI 120 ++ LC+ + + + Q +Y A Y + + +C + Sbjct: 57 KVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDI-KEPRFPFHAAECLL 115 Query: 121 GAKNIDNAMQCFYH----IINNCEDDSVKSKAQAYIELLNDNSE 160 + A + I + E + ++ + +E + E Sbjct: 116 QKGELAEAESGLFLAQELIADKTEFKELSTRVSSMLEAIKLKKE 159
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 34.6 bits (79), Expect = 3e-04 Identities = 22/126 (17%), Positives = 49/126 (38%), Gaps = 5/126 (3%) Query: 4 ISLLLFILLLCGCKQQE-LLNHLDQQQANDVLAVLQRHNINAEKKDQGKTGFSIYVEPTD 62 +++++ ++L L ++L Q ++A L + NI + I V Sbjct: 35 VAIVVAMVLWAKTPDYRTLFSNLSDQDGGAIVAQLTQMNIPYRFANGSGA---IEVPADK 91 Query: 63 FASAVDWLKIYNLPGKPDIQISQMFPADALVSSPRAEKARLYSAIEQRLEQSLKIMDGIV 122 L LP + + + S +E+ A+E L ++++ + + Sbjct: 92 VHELRLRLAQQGLPKGGAVGFE-LLDQEKFGISQFSEQVNYQRALEGELARTIETLGPVK 150 Query: 123 SSRVHV 128 S+RVH+ Sbjct: 151 SARVHL 156
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 28.1 bits (62), Expect = 0.012 Identities = 18/98 (18%), Positives = 31/98 (31%), Gaps = 2/98 (2%) Query: 31 FTEIVVTSMLNGLPALSAGAHAILTSLHAAGLNANDYGAY--SRAWAESNAEARREAERQ 88 E V P+ + A + + + N+ A + E EA+ + Sbjct: 1020 VDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKAN 1079 Query: 89 RIENEKDRQRIAAMYATPEEIAKEAAERKERKAELERR 126 NE + E + A KE KA++E Sbjct: 1080 TQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETE 1117
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 43.0 bits (101), Expect = 4e-07 Identities = 52/246 (21%), Positives = 79/246 (32%), Gaps = 55/246 (22%) Query: 1 MNKVIAVSALAMAGMFSTQALADESKTGFYVTGKAGASVMSLADQRFLSGDGEETSKYKG 60 M K A+A+AG F+T A A +Y K G S D F++ Sbjct: 1 MKKTAIAIAVALAG-FATVAQAAPKDNTWYTGAKLGWS--QYHDTGFIN---------NN 48 Query: 61 GDGHDTVFSGGIAAGYDFYPQFSIPVRTELEFYARGKADSKYNVDKDSWSGGYWRDDLKN 120 G H+ G GY P E+ + G+ K +V+ + Sbjct: 49 GPTHENQLGAGAFGGYQVNPYVGF----EMGYDWLGRMPYKGSVE-----------NGAY 93 Query: 121 EVSVNTLMLNAYYDFRNDSAFTPWVSAGIGYARIHQKTTGISTWDYGYGSSGRESLSRSG 180 + L Y +D + G R K YG + +S Sbjct: 94 KAQGVQLTAKLGYPITDD--LDIYTRLGGMVWRADTK-------SNVYGKNHDTGVS--- 141 Query: 181 SADNFAWSFGAGVRYDVTPDIALDLSYRYLDAGDSSVSYKDEWGDKYKSEVDVKSHDIML 240 F GV Y +TP+IA L Y++ + GD + + + L Sbjct: 142 ------PVFAGGVEYAITPEIATRLEYQWT----------NNIGDAHTIGTRPDNGMLSL 185 Query: 241 GVTYNF 246 GV+Y F Sbjct: 186 GVSYRF 191
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 30.6 bits (69), Expect = 0.023 Identities = 25/149 (16%), Positives = 47/149 (31%), Gaps = 17/149 (11%) Query: 483 HHVKADVDGVLVLFPAGERGRFSPSPEFITAVLTLRLGSVVALIDNS------------L 530 H + G +++FP +I +L R G + L L Sbjct: 287 HQLSTAEIGSVIIFPGTMSVIIF---GYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFL 343 Query: 531 DQAEQKVLENAINNNASFSDDEKRSLHAYLTWQLHTPANMTGMK--SRIELLGAAEKSAV 588 + + I K + ++ L GM + L A+ Sbjct: 344 LETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAI 403 Query: 589 GKVIVSVACSDGRITPAEIKQLEKIYTSL 617 ++S+ D R+ P E+ Q +Y++L Sbjct: 404 VGGLLSIPLLDQRLLPMEVDQSTYLYSNL 432
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 31.8 bits (72), Expect = 8e-04 Identities = 18/48 (37%), Positives = 24/48 (50%), Gaps = 5/48 (10%) Query: 1 MRRTR--AGFTLLEMLVAIAIFASLA-LMAQQVTNGVTR--VNSAVAD 43 MR T GFTLLE++V I I LA L+ + + AV+D Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSD 48
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 33.4 bits (76), Expect = 9e-05 Identities = 13/24 (54%), Positives = 18/24 (75%) Query: 2 KRGFTLLEVMLALAIFALAATAVL 25 +RGFTLLE+ML L + ++A VL Sbjct: 3 QRGFTLLEMMLILLLMGVSAGMVL 26
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 74.2 bits (182), Expect = 4e-19 Identities = 41/196 (20%), Positives = 69/196 (35%), Gaps = 41/196 (20%) Query: 1 MPERGFTLLEIMLVIFLIGLASSGVVQTFATDSEPPAKKAAQDFLTRFAQFKDRAVIEGQ 60 M +RGFTLLE+ML++ L+G+++ V+ F + A + F + + R + GQ Sbjct: 1 MRQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQTLARFEAQLRFVQQRGLQTGQ 60 Query: 61 TLGVLIDAPGYQFMQRRQGQWLPVSATRLSAQVTVPKQVQMLLQPGSDIWQKEYALELQR 120 GV + +QF+ + P D W L L+ Sbjct: 61 FFGVSVHPDRWQFLVLEARDGADPA-------------------PADDGWSGYRWLPLRA 101 Query: 121 RRL----TLHDIELEL-----QKEAKKKTPQIRFSPFEPATPFTLRFYSAAQNACWAVKL 171 R+ ++ +L L + P + P TPF L L Sbjct: 102 GRVATSGSIAGGKLNLAFAQGEAWTPGDNPDVLIFPGGEMTPFRLT-------------L 148 Query: 172 AHDGALSLNQCDERMP 187 ++ N E +P Sbjct: 149 GEAPGIAFNARGESLP 164
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 218 bits (556), Expect = 2e-76 Identities = 91/146 (62%), Positives = 109/146 (74%), Gaps = 3/146 (2%) Query: 6 RTQKPRAGFTLLEVMVVIVILGVLASLVVPNLLGNKEKADRQKAISDIVALENALDMYRL 65 R + GFTLLE+MVVIVI+GVLASLVVPNL+GNKEKAD+QKA+SDIVALENALDMY+L Sbjct: 2 RATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKL 61 Query: 66 DNGRYPTTEQGLEALIQQPANMADARNYRTGGYIKRLPKDPWGNDYQYLSPGEKGLFDVY 125 DN YPTT QGLE+L++ P A NY GYIKRLP DPWGNDY ++PGE G +D+ Sbjct: 62 DNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDLL 121 Query: 126 TLGADGQENGEGAGADIGNWNLQEFQ 151 + G DG+ E DI NW L + + Sbjct: 122 SAGPDGEMGTED---DITNWGLSKKK 144
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 455 bits (1171), Expect = e-162 Identities = 226/406 (55%), Positives = 302/406 (74%), Gaps = 1/406 (0%) Query: 1 MALFYYQALERNGRKTKGMIEADSARHARQLLRGKELIPVHI-EARMNTSSGGMLQRRRH 59 MA ++YQAL+ G+K +G EADSAR ARQLLR + L+P+ + E R + G Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 60 AHRRVAAADLALFTRQLATLVQAAMPLETCLQAVSEQSEKLHVKSLGMALRSRIQEGYTL 119 R++ +DLAL TRQLATLV A+MPLE L AV++QSEK H+ L A+RS++ EG++L Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 120 SDSLREHPRVFDSLFCSMVAAGEKSGHLDVVLNRLADYTEQRQRLKSRLLQAMLYPLVLL 179 +D+++ P F+ L+C+MVAAGE SGHLD VLNRLADYTEQRQ+++SR+ QAM+YP VL Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 180 VVATGVVTILLTAVVPKIIEQFDHLGHALPVSTRTLIAMSDALQASGVYWLAGLLGLLVL 239 VVA VV+ILL+ VVPK++EQF H+ ALP+STR L+ MSDA++ G + L LL + Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMA 240 Query: 240 GQRLLKNPAMRLRWDKTLLRLPVIGRVARGLNTARFSRTLSILTASSVPLLEGIQTAAAV 299 + +L+ R+ + + LL LP+IGR+ARGLNTAR++RTLSIL AS+VPLL+ ++ + V Sbjct: 241 FRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 300 SANRYVEQQLLLAADRVREGSSLRAALAELRLFPPMMLYMIASGEQSGELETMLEQAAVN 359 +N Y +L LA D VREG SL AL + LFPPMM +MIASGE+SGEL++MLE+AA N Sbjct: 301 MSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADN 360 Query: 360 QEREFDTQVGLALGLFEPALVVMMAGVVLFIVIAILEPMLQLNNMV 405 Q+REF +Q+ LALGLFEP LVV MA VVLFIV+AIL+P+LQLN ++ Sbjct: 361 QDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 574 bits (1482), Expect = 0.0 Identities = 295/668 (44%), Positives = 431/668 (64%), Gaps = 34/668 (5%) Query: 24 LLPLVLAAALCSSPVWAEEATFTANFKDTDLKSFIETVGANLNKTIIMGPGVQGKVSIRT 83 L L++ AAL P AEE F+A+FK TD++ FI TV NLNKT+I+ P V+G +++R+ Sbjct: 11 SLTLLIFAALLFRPAAAEE--FSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRS 68 Query: 84 MTPLNERQYYQLFLNLLEAQGYAVVPMENDVLKVVKSSAAKVEPLPLVGEGSDNYAGDEM 143 LNE QYYQ FL++L+ G+AV+ M N VLKVV+S AK +P+ + + GDE+ Sbjct: 69 YDMLNEEQYYQFFLSVLDVYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPG-IGDEV 127 Query: 144 VTKVVPVRNVSVRELAPILRQMIDSAGSGNVVNYDPSNVIMLTGRASVVERLTEVIQRVD 203 VT+VVP+ NV+ R+LAP+LRQ+ D+AG G+VV+Y+PSNV+++TGRA+V++RL +++RVD Sbjct: 128 VTRVVPLTNVAARDLAPLLRQLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVD 187 Query: 204 HAGNRTEEVIPLDNASASEIARVLESLTKNSGENQ-PATLKSQIVADERTNSVIVSGDPA 262 +AG+R+ +PL ASA+++ +++ L K++ ++ P ++ + +VADERTN+V+VSG+P Sbjct: 188 NAGDRSVVTVPLSWASAADVVKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSGEPN 247 Query: 263 TRDKMRRLIRRLDSEMERSGNSQVFYLKYSKAEDLVDVLKQVSGTLTAAKEEAEGTVGSG 322 +R ++ +I++LD + GN++V YLKY+KA DLV+VL +S T+ + K+ A+ + Sbjct: 248 SRQRIIAMIKQLDRQQATQGNTKVIYLKYAKASDLVEVLTGISSTMQSEKQAAKPV-AAL 306 Query: 323 REVVSIAASKHSNALIVTAPQDIMQSLQSVIEQLDIRRAQVHVEALIVEVAEGSNINFGV 382 + + I A +NALIVTA D+M L+ VI QLDIRR QV VEA+I EV + +N G+ Sbjct: 307 DKNIIIKAHGQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLGI 366 Query: 383 QWASKDAGLMQFANGTQIPIGTLGAAISQAKPQKGSTVISENGATTINPDTNGDLST-LA 441 QWA+K+AG+ QF N + +PI T A + +G +S+ LA Sbjct: 367 QWANKNAGMTQFTN-SGLPISTAIAG-------------------ANQYNKDGTVSSSLA 406 Query: 442 QLLSGFSGTAVGVVKGDWMALVQAVKNDSSSNVLSTPSITTLDNQEAFFMVGQDVPVLTG 501 LS F+G A G +G+W L+ A+ + + +++L+TPSI TLDN EA F VGQ+VPVLTG Sbjct: 407 SALSSFNGIAAGFYQGNWAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVPVLTG 466 Query: 502 STVGSNNSNPFNTVERKKVGIMLKVTPQINEGNAVQMVIEQEVSKVEGQTS-----LDVV 556 S S N FNTVERK VGI LKV PQINEG++V + IEQEVS V S L Sbjct: 467 SQTTSG-DNIFNTVERKTVGIKLKVKPQINEGDSVLLEIEQEVSSVADAASSTSSDLGAT 525 Query: 557 FGERKLKTTVLANDGELIVLGGLMDDQAGESVAKVPLLGDIPLIGNLFKSTADKKEKRNL 616 F R + VL GE +V+GGL+D ++ KVPLLGDIP+IG LF+ST+ K KRNL Sbjct: 526 FNTRTVNNAVLVGSGETVVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRNL 585 Query: 617 MVFIRPTILRDGMAADGVSQRKYNYMRAEQIYR--DEQGLSLMPHTAQPVLPAQNQALPP 674 M+FIRPT++RD S +Y Q + E +++ + P Q+ A Sbjct: 586 MLFIRPTVIRDRDEYRQASSGQYTAFNDAQSKQRGKENNDAMLNQDLLEIYPRQDTAAFR 645 Query: 675 EVRAFLNA 682 +V A ++A Sbjct: 646 QVSAAIDA 653
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 101 bits (254), Expect = 6e-28 Identities = 66/278 (23%), Positives = 108/278 (38%), Gaps = 38/278 (13%) Query: 1 MLLIISAKMAHSLWRYISFSAEYTA-VSQPVNKPSRVDAKTFDKNDVQLISQQNWFGKYQ 59 ++L+ ++A WR A VS P++ + ND L FG Sbjct: 22 LMLLFCQQLAMIFWR---IGLPDNAPVSSVQITPAQARQQPVTLNDFTL------FGVSP 72 Query: 60 PV--AAQVKQPEPVPVAETRLNVVLRGIAFG---ARPGAVIEEGGKQQVYLQGETLGSHN 114 A + + + + LN+ L G+ G +R A+I + +Q E + +N Sbjct: 73 EKNKAGALDASQMSNLPPSTLNLSLTGVMAGDDDSRSIAIISKDNEQFSRGVNEEVPGYN 132 Query: 115 AVIEEINRDHVMLRYQGKIERLSLAEEERSTVAVTNKKAVSDEAKQAVAEPAVSVPVEIP 174 A I I D V+L+YQG+ E L L +E S SD A + Sbjct: 133 AKIVSIRPDRVVLQYQGRYEVLGLYSQEDSG---------SDGVPGAQVNEQLQ------ 177 Query: 175 AAVRQALAKDPQKIFNYIQLTPVRKEG-IVGYAAKPGADRSLFDASGFKEGDIAIALNQQ 233 + + +Y+ +P+ + + GY PG F G ++ D+A+ALN Sbjct: 178 -------QRASTTMSDYVSFSPIMNDNKLQGYRLNPGPKSDSFYRVGLQDNDMAVALNGL 230 Query: 234 DFTDPRAMIALMRQLPSMDSIQLTVLRKGARHDISIAL 271 D D M ++ + + LTV R G R DI + Sbjct: 231 DLRDAEQAKKAMERMADVHNFTLTVERDGQRQDIYMEF 268
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 282 bits (723), Expect = 8e-98 Identities = 110/274 (40%), Positives = 150/274 (54%), Gaps = 12/274 (4%) Query: 1 MLFDVFQQYPTAMPVLATVGGLIIGSFLNVVIWRYPIML-RQQMAEFHGEMSSAQSKI-- 57 +L ++ P L + L+IGSFLNVVI R PIML R+ AE+ + + Sbjct: 3 LLLELAHGLPWLYFSLVFLFSLMIGSFLNVVIHRLPIMLEREWQAEYRSYFNPDDEGVDE 62 Query: 58 ---SLALPRSHCPHCQQTIRIRDNIPLFSWLMLKGRCRDCQAKISKRYPLVELLTALAFL 114 +L +PRS CPHC I +NIPL SWL L+GRCR CQA IS RYPLVELLTAL + Sbjct: 63 PPYNLMVPRSCCPHCNHPITALENIPLLSWLWLRGRCRGCQAPISARYPLVELLTALLSV 122 Query: 115 LASLVWPESGWGLAVMILSAWLIAASVIDLDHQWLPDVFTQGVLWTGLIAAWAQQSPLTL 174 ++ LA ++L+ L+A + IDLD LPD T +LW GL+ ++L Sbjct: 123 AVAMTLAPGWGTLAALLLTWVLVALTFIDLDKMLLPDQLTLPLLWGGLLFNL-LGGFVSL 181 Query: 175 QDAVTGVLVGFITFYSLRWIAGIVLRKEALGMGDVLLFAALGGWVGALSLPNVALIASCC 234 DAV G + G++ +SL W ++ KE +G GD L AALG W+G +LP V L++S Sbjct: 182 GDAVIGAMAGYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALPIVLLLSSLV 241 Query: 235 GLIYAVI-----TKRGSTTLPFGPCLSLGGIATL 263 G + S +PFGP L++ G L Sbjct: 242 GAFMGIGLILLRNHHQSKPIPFGPYLAIAGWIAL 275
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 49.2 bits (117), Expect = 4e-08 Identities = 24/60 (40%), Positives = 30/60 (50%), Gaps = 3/60 (5%) Query: 32 SSDTPPVDSGTGSLPEVKPDPTPNPEPTPEPTPDPEPTPEP---IPDPEPTPEPEPEPVP 88 S T + V+P P P EP PEP P PEP E I P+P P+P+P+PV Sbjct: 50 ISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVK 109 Score = 41.9 bits (98), Expect = 9e-06 Identities = 16/92 (17%), Positives = 27/92 (29%), Gaps = 2/92 (2%) Query: 33 SDTPPVDSGTGSLPEVKPDPTPNPEPTPEPTPDPEPTPEPIPDPEPTPEPEPEPVPTKTG 92 +D P + PE +P P PEP PEP + E + V Sbjct: 58 ADLEPPQAVQ-PPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKR 116 Query: 93 YLTLGGSQRVTGATCNGESSDGFTFKPGEDVT 124 + S+ + N + + + Sbjct: 117 DVKPVESRPASPFE-NTAPARPTSSTATAATS 147 Score = 40.7 bits (95), Expect = 2e-05 Identities = 18/59 (30%), Positives = 23/59 (38%), Gaps = 2/59 (3%) Query: 35 TPPVDSGTGSLPEVKPDPTPNPEPTPEPTPDPEPTPEPIPDP--EPTPEPEPEPVPTKT 91 P + +P +P PEP +PEP PEPIP+P E E K Sbjct: 45 APAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKP 103 Score = 40.7 bits (95), Expect = 2e-05 Identities = 20/96 (20%), Positives = 28/96 (29%), Gaps = 7/96 (7%) Query: 29 SGSSSDTPPVDSGTGSLPEVKPDPTPNPEPT---PEPTPDPEPTPEPIPDPEPTPEPEPE 85 + P V PE +P P P E +P P P+P P+P+ E Sbjct: 65 AVQPPPEPVV----EPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKP 120 Query: 86 PVPTKTGYLTLGGSQRVTGATCNGESSDGFTFKPGE 121 R T +T +S T Sbjct: 121 VESRPASPFENTAPARPTSSTATAATSKPVTSVASG 156 Score = 35.0 bits (80), Expect = 0.001 Identities = 17/40 (42%), Positives = 17/40 (42%) Query: 50 PDPTPNPEPTPEPTPDPEPTPEPIPDPEPTPEPEPEPVPT 89 P P T D EP P PEP EPEPEP P Sbjct: 44 PAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPI 83 Score = 30.7 bits (69), Expect = 0.039 Identities = 11/40 (27%), Positives = 13/40 (32%) Query: 52 PTPNPEPTPEPTPDPEPTPEPIPDPEPTPEPEPEPVPTKT 91 P P + + P P P P EPEP P Sbjct: 44 PAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPI 83
>FIMBRIALPAPE#Escherichia coli: P pili tip fibrillum papE protein signature. Length = 173 Score = 28.1 bits (62), Expect = 0.015 Identities = 36/163 (22%), Positives = 66/163 (40%), Gaps = 35/163 (21%) Query: 14 AMILSNNVFADEGHGIVKFKGEVISAPCSIKPGDEDLTVNLGEVADTVLKSDQKSLAE-- 71 A+++S +V A + + FKG++I C++ ++ VN G++ L + + Sbjct: 15 AVLMSQHVHAADN---LTFKGKLIIPACTV----QNAEVNWGDIEIQNLVQSGGNQKDFT 67 Query: 72 -----PFTIHLQDCMLSQGGTTYSKAKVTFTTANTMTGQSDLLKNTKETEIGGATGVGVR 126 P+++ ++ G T + V T+ + G L N+ + IG A Sbjct: 68 VDMNCPYSLGTMKVTITSNGQTGNSILVPNTSTASGDGLLIYLYNSNNSGIGNA------ 121 Query: 127 ILDSQSGEVTLGTPVV---ITFNNTNS----YQELNFKARMES 162 VTLG+ V IT Y +L +K M+S Sbjct: 122 --------VTLGSQVTPGKITGTAPARKITLYAKLGYKGNMQS 156
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 201 bits (513), Expect = 2e-61 Identities = 66/251 (26%), Positives = 111/251 (44%), Gaps = 12/251 (4%) Query: 22 CSLSVIIIGCA-------SAYAVEFNKDLIEAEDRENVNLSQFETDGQLPVGKYSLSTLI 74 + + CA S+ + FN + + + +LS+FE +LP G Y + + Sbjct: 25 GFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYL 84 Query: 75 NNKRTPIHLDLQWVLIDN--QTAVCVTPEQLTLLGFTDEFIEKTQQNLIDGCYPIEK-EK 131 NN D+ + D+ C+T QL +G + D C P+ Sbjct: 85 NNGYMA-TRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLTSMIH 143 Query: 132 QITTYLDKGKMQLSISAPQAWLKYKDANWTPPELWNHGIAGAFLDYNLYASHYAPHQGDN 191 T LD G+ +L+++ PQA++ + + PPELW+ GI L+YN + G N Sbjct: 144 DATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGN 203 Query: 192 SQNISSYGQAGVNLGAWRLRTDYQYDQSFNNGKS-QATNLDFPRIYLFRPIPAMNAKLTI 250 S Q+G+N+GAWRLR + + + ++ S +L R I + ++LT+ Sbjct: 204 SHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTL 263 Query: 251 GQYDTESSIFD 261 G T+ IFD Sbjct: 264 GDGYTQGDIFD 274
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 422 bits (1086), Expect = e-140 Identities = 152/577 (26%), Positives = 266/577 (46%), Gaps = 51/577 (8%) Query: 1 MLPPDLRGYAPQITGVAQTNAKVTVSQNNRIIYQENVPPGPFAITNLFNT-LQGQLDVKV 59 MLP RG+AP I G+A+ A+VT+ QN IY VPPGPF I +++ G L V + Sbjct: 289 MLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTI 348 Query: 60 EEEDGRVTQWQVASNSIPYLTRKGQIRYTTAMGKPTSVGGDSLQQPFFWTGEFSWGWLNN 119 +E DG + V +S+P L R+G RY+ G+ S G ++P F+ G Sbjct: 349 KEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYRS-GNAQQEKPRFFQSTLLHGLPAG 407 Query: 120 VSLYGGSVLTNRDYQSLAAGVGFNLNSLGSLSFDVTRSDAQLHNQDKETGYSYRANYSKR 179 ++YGG+ L +R Y++ G+G N+ +LG+LS D+T++++ L + + G S R Y+K Sbjct: 408 WTIYGGTQLADR-YRAFNFGIGKNMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKS 466 Query: 180 FESTGSQLTFAGYRFSDKNFVTMNEYIND--------------------TNHYTNYQNEK 219 +G+ + GYR+S + + T++Y N++ Sbjct: 467 LNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKR 526 Query: 220 ESYIVTFNQYLESLRLNTYVSLARNTYWDAS-SNVNYSLSLSRDFDIGPLKNVSTSLTFS 278 +T Q L Y+S + TYW S + + L+ F ++++ +L++S Sbjct: 527 GKLQLTVTQQLGR-TSTLYLSGSHQTYWGTSNVDEQFQAGLNTAF-----EDINWTLSYS 580 Query: 279 RIN--WEEDNQDQLYLNISIPWGTSR-----------TLSYGMQRNQDNEISHTASWYDS 325 W++ L LN++IP+ + SY M + + +++ A Y + Sbjct: 581 LTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGT 640 Query: 326 --SDRNNSWSVSASGDNDEFKDMKASLRASYQHNTENGRLYLSGTSQRDSYYSLNASWNG 383 D N S+SV + ++ A+ + G + + D L +G Sbjct: 641 LLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIGYSHSDD-IKQLYYGVSG 699 Query: 384 SFTATRHGAAFHDYSGSADSRFMIDADGTEDIPLNNKRAV-TNRYGIGVIPSVSSYITTS 442 A +G D+ ++ A G +D + N+ V T+ G V+P + Y Sbjct: 700 GVLAHANGVTLGQPLN--DTVVLVKAPGAKDAKVENQTGVRTDWRGYAVLPYATEYRENR 757 Query: 443 LSVDTRNLPENVDIENSVITTTLTEGAIGYAKLDTRKGYQIIGVIRLADGSHPPLGISVK 502 +++DT L +NVD++N+V T GAI A+ R G +++ + + P G V Sbjct: 758 VALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKLLMTLT-HNNKPLPFGAMVT 816 Query: 503 DETSHKELGLVADGGFVYLNGIQDDNKLALRWGDKSC 539 E+S + G+VAD G VYL+G+ K+ ++WG++ Sbjct: 817 SESS-QSSGIVADNGQVYLSGMPLAGKVQVKWGEEEN 852
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 51.6 bits (123), Expect = 7e-09 Identities = 47/287 (16%), Positives = 92/287 (32%), Gaps = 16/287 (5%) Query: 197 PNNAFDAEGLTKLTQETERRRRERNEVEQDVEVAVREKNRDALSRKLEIEQQEAFMTLEQ 256 N A+ + + E R A + + ++ E +QE+ + Sbjct: 999 TPNNIQAD-VPSVPSNNEEIARVDEAPVPPPAPATPSETTETVA---ENSKQESKTVEKN 1054 Query: 257 EQQVKTRTAEQNARIAAFEAERRREAE-QTRILAERQIQETEIDREQAVRSRKVEAEREV 315 EQ TA+ R A EA+ +A QT +A+ + E + + VE E + Sbjct: 1055 EQDATETTAQN--REVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKA 1112 Query: 316 RIKEIEQQQVTEIANQTKSIAIAAKSEQ---QSQAEARANLALAEAVSAQQNVETTRQTA 372 +++ + Q+V ++ +Q +++ Q + E + + E S T Q A Sbjct: 1113 KVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPA 1172 Query: 373 EADRAKQVALIAAAQDAET------KAVELTVRAKAEKEAAEMQAAAIVELAEATRKKGL 426 + + + + T T +E + R Sbjct: 1173 KETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPH 1232 Query: 427 AEAEAQRALNDAINVLSDEQTSLKFKLALLQALPAVIEKSVEPMKSI 473 A + ND V + TS L A ++ K++ Sbjct: 1233 NVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAV 1279
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 29.0 bits (65), Expect = 0.028 Identities = 10/37 (27%), Positives = 20/37 (54%) Query: 347 GVFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRL 383 G FD + GH+ + +L D++ VAV + + + + Sbjct: 7 GSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPM 43
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 537 bits (1385), Expect = 0.0 Identities = 173/397 (43%), Positives = 254/397 (63%), Gaps = 11/397 (2%) Query: 7 VLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAFLSVN-GGEPAP--LAHHSYEGA 63 +LVINCGSSS+K+ ++++ D VL G+A+ I ++ L+ N GE ++ A Sbjct: 3 ILVINCGSSSLKYQLIESKDGNVLAKGLAERIGINDSLLTHNANGEKIKIKKDMKDHKDA 62 Query: 64 LKAIAFELEKRNLN-----DSVALIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAPLH 118 +K + L + + +GHR+ HGG FT S +ITD+V+ I LAPLH Sbjct: 63 IKLVLDALVNSDYGVIKDMSEIDAVGHRVVHGGEYFTSSVLITDDVLKAITDCIELAPLH 122 Query: 119 NYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLPWKYYEELGVRRYGFHGTS 178 N AN+ GI++ Q+ P V VAVFDT+FHQTM AYLY +P++YY + +R+YGFHGTS Sbjct: 123 NPANIEGIKACTQIMPDVPMVAVFDTAFHQTMPDYAYLYPIPYEYYTKYKIRKYGFHGTS 182 Query: 179 HRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSG 238 H+YVSQRA +LN + ++ HLGNG+SI AV+NG+S+DTSMG TPLEGL MGTRSG Sbjct: 183 HKYVSQRAAEILNKPIESLKIITCHLGNGSSIAAVKNGKSIDTSMGFTPLEGLAMGTRSG 242 Query: 239 DVDFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLR-VLEKAWHEGHERAQLAI 297 +D +S++ + N S ++ ++NK+SG+ GISG+SSD R + + A+ G +RAQLA+ Sbjct: 243 SIDPSIISYLMEKENISAEEVVNILNKKSGVYGISGISSDFRDLEDAAFKNGDKRAQLAL 302 Query: 298 KTFVHRIARHIAGHAASLRRLDGIIFTGGIGENSSLIRRLVMEHLAVLGLEIDTEMNNRS 357 F +R+ + I +AA++ +D I+FT GIGEN IR +++ L LG ++D E N Sbjct: 303 NVFAYRVKKTIGSYAAAMGGVDVIVFTAGIGENGPEIREFILDGLEFLGFKLDKEKNKVR 362 Query: 358 NSCGERIVSSENARVICAVIPTNEEKMIALDAIHLGK 394 E I+S+ +++V V+PTNEE MIA D + + Sbjct: 363 GE--EAIISTADSKVNVMVVPTNEEYMIAKDTEKIVE 397
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 29.0 bits (65), Expect = 0.014 Identities = 8/22 (36%), Positives = 13/22 (59%) Query: 4 VLITGATGLVGGHLLRMLINEP 25 L+TGA G +G H+ + L+ Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAG 24
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 73.4 bits (180), Expect = 2e-15 Identities = 69/313 (22%), Positives = 109/313 (34%), Gaps = 77/313 (24%) Query: 396 IMGHVDHGKTSLLDYI-----RSTKVASGEAG-------------GITQHIGAYHVETEN 437 ++ HVD GKT+L + + T++ S + G GIT G + EN Sbjct: 8 VLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWEN 67 Query: 438 GMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAQVPVVVAV 497 + +DTPGH F + R D +L+++A DGV QT + +P + + Sbjct: 68 TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFI 127 Query: 498 NKIDKPEADPDRV----KNELSQYGI-----------------LPEEWG----------- 525 NKID+ D V K +LS + E+W Sbjct: 128 NKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGNDDLLE 187 Query: 526 ---------------GESQFV---------HVSAKAGTGIDELLDAILLQAEVLELKAVR 561 ES H SAK GID L++ I + Sbjct: 188 KYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVIT--NKFYSSTHRG 245 Query: 562 KGMASGAVIESFLDKGRGPVATVLVREGTLHKGDIVL-CGFEYGRVRAMRNELGQEVLEA 620 + G V + + R +A + + G LH D V E ++ M + E+ + Sbjct: 246 QSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKIKITEMYTSINGELCKI 305 Query: 621 GPSIPVEILGLSG 633 + EI+ L Sbjct: 306 DKAYSGEIVILQN 318
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 61.0 bits (148), Expect = 3e-14 Identities = 21/129 (16%), Positives = 33/129 (25%), Gaps = 12/129 (9%) Query: 3 KKTLLAYTIGFAFSP-PANADGIEIAAVDFDRETLKSLGVDPNISHYFSRSARFLPGEYS 61 K L + + + A + A + F+ L F PG Y Sbjct: 20 KHRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYR 79 Query: 62 LIVSVNGEKKGNIATRFDENGD-----ICLDQAFLQQAGLKIPSEEK------NGCYDYI 110 + + +N F+ CL +A L GL S + C Sbjct: 80 VDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLT 139 Query: 111 LSYPGTTIT 119 T Sbjct: 140 SMIHDATAQ 148
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 326 bits (836), Expect = e-103 Identities = 146/697 (20%), Positives = 265/697 (38%), Gaps = 76/697 (10%) Query: 2 SSRAEFSNGSSDYSQAALEGGININDWMLRSHQFLTQTNGTFSN------QNSSTYLQRT 55 +S G+S Y+ L+ G+NI W LR + + + S+ Q+ +T+L+R Sbjct: 194 NSVQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERD 253 Query: 56 FTDLKTLMRAGEVNLNNSVLEGASIYGIEIAPDNALQTS---GSGVQVTGIANTSQARVE 112 L++ + G+ + +G + G ++A D+ + G + GIA A+V Sbjct: 254 IIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARG-TAQVT 312 Query: 113 IRQQGVLIHSILVPAGAFTIPDVPVRNGNSDLNVTVVETDGSSHNYIVP-STLFNQHVES 171 I+Q G I++ VP G FTI D+ + DL VT+ E DGS+ + VP S++ E Sbjct: 313 IKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREG 372 Query: 172 FQGYRFAIGRVDDDY--DESPWVISASSGWNLTRWSAMNGGVIVAENYQAASIRSSLVPL 229 Y G E P ++ L + GG +A+ Y+A + Sbjct: 373 HTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMG 432 Query: 230 PDLTVSSQISTSQ---DTKDSLQGQKYRLDANYNLPFSLGLTTSLTR-----SDRHYREL 281 +S ++ + GQ R YN + T++ S Y Sbjct: 433 ALGALSVDMTQANSTLPDDSQHDGQSVRF--LYNKSLN-ESGTNIQLVGYRYSTSGYFNF 489 Query: 282 SEAIDD------------------------DYTDPTKSTYALGLNWSNSILGGFNISGYK 317 ++ + + L + +SG Sbjct: 490 ADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSH 549 Query: 318 TYSYDGDNDSSNLNINWNKAFKHATVSVNWQHQLSASENNEDDGDLFYVNISIPFGR--- 374 + N N AF+ ++++ +A + D +N++IPF Sbjct: 550 QTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQM--LALNVNIPFSHWLR 607 Query: 375 --------SNTATLYTRHDDH-KTHYGTGVMGVV--SDEMSYYVNAERDHDER---ETSL 420 +A+ HD + + GV G + + +SY V ++ Sbjct: 608 SDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTG 667 Query: 421 NGSISSNLHYTQVSLAAGASGSDSRTYNGTMSGGIAVHDQGVTFSPWTINDTFAIAKMDN 480 +++ Y ++ S D + +SGG+ H GVT +NDT + K Sbjct: 668 YATLNYRGGYGNANIGYSHS-DDIKQLYYGVSGGVLAHANGVTLGQ-PLNDTVVLVKAP- 724 Query: 481 NIAGVRITSQAGPVWTDFRGNAVIPSIQPWRTSGVEIDTASLPKNVDIGNGTKMIKQGRG 540 ++ +Q G V TD+RG AV+P +R + V +DT +L NVD+ N + RG Sbjct: 725 GAKDAKVENQTG-VRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRG 783 Query: 541 AVGKVGFSAITQRRALLNITLSDGKKLPRGVAIEDSEGNYLTTSVDDGVVFLNNIKPDMV 600 A+ + F A + L+ +T + K LP G + D+G V+L+ + Sbjct: 784 AIVRAEFKARVGIKLLMTLT-HNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGK 842 Query: 601 LDIK---DEQQSCRIHLTFPEDAPKDVFYETATGECQ 634 + +K +E C + P ++ + + + + EC+ Sbjct: 843 VQVKWGEEENAHCVANYQLPPESQQQLLTQL-SAECR 878
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 43.5 bits (102), Expect = 2e-06 Identities = 39/199 (19%), Positives = 70/199 (35%), Gaps = 19/199 (9%) Query: 143 DLAGNATDQANGVQPAPGTTSAENTQQDVSL-----------------PPISSTPTQGQT 185 DL ++ N T+ N Q DV PP +TP++ Sbjct: 979 DLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTE 1038 Query: 186 PVATDGQQRVEVQGDLNNALTQPQNQQQLNNVAVNSTLPTEPATVAPVRNGNASRDTAKT 245 VA + +Q + T+ Q + S + T ++G+ +++T T Sbjct: 1039 TVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTT 1098 Query: 246 QTAERPSTTRPARQQAVIEPKKPQATVKTEPKPVAQTPKRTEPAAPVASTKAPAATSTPA 305 +T E + + + + E + V ++ P + + +P A A P Sbjct: 1099 ETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEP 1158 Query: 306 PKETATTAPVQTASPAQTT 324 +T TTA T PA+ T Sbjct: 1159 QSQTNTTA--DTEQPAKET 1175 Score = 42.0 bits (98), Expect = 4e-06 Identities = 41/203 (20%), Positives = 68/203 (33%), Gaps = 10/203 (4%) Query: 126 APSTTSSDQTASGEKSIDLAGNATDQANGVQPAPGTTSAENTQQDVSLPPISST-PTQGQ 184 P+ +D + + ++A D+A PAP T S + S T Q Sbjct: 999 TPNNIQADVPSVPSNNEEIA--RVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQ 1056 Query: 185 TPVATDGQQRVEVQGDLNNALTQPQN----QQQLNNVAVNSTLPTEPATVAPVRNGNASR 240 T Q R + +N Q Q +T E ATV + A Sbjct: 1057 DATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVE--KEEKAKV 1114 Query: 241 DTAKTQTAERPSTTRPARQQAVIEPKKPQATVKTEPKPVAQTPKRTEPAAPVASTKAPAA 300 +T KTQ + ++ +Q+ E +PQA E P + A T+ PA Sbjct: 1115 ETEKTQEVPKVTSQVSPKQEQS-ETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAK 1173 Query: 301 TSTPAPKETATTAPVQTASPAQT 323 ++ ++ T + + Sbjct: 1174 ETSSNVEQPVTESTTVNTGNSVV 1196
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 32.1 bits (73), Expect = 8e-04 Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 18/91 (19%) Query: 32 FYDSDQEIEKRTGADVGWVFDLEGEEGFRD----------REEKVINELTEKQGIVLATG 81 FYD + KR + GW+ + G+R E + I +L E+ IV+A+G Sbjct: 136 FYDEETA--KRLAREKGWIVKEDSGRGWRRVVPSPDPKGHVEAETIKKLVERGVIVIASG 193 Query: 82 GGSVKSRETRNRLSARGVVVYLETTIEKQLA 112 GG V + +GV E I+K LA Sbjct: 194 GGGVPVILEDGEI--KGV----EAVIDKDLA 218
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 287 bits (735), Expect = 1e-93 Identities = 80/301 (26%), Positives = 132/301 (43%), Gaps = 18/301 (5%) Query: 107 LENRSITLQYADAGELAKAGEKLLSAKGSMTVDKRTNRLLLRDNKTALSALEQWVAQMDL 166 L + +I D + +A SA+ + D N +++RD+ + ++ + +D Sbjct: 219 LSDATIQQVTVDNQRIPQAAT-RASAQARVEADPSLNAIIVRDSPERMPMYQRLIHALDK 277 Query: 167 PVGQVELSAHIVTINEKSLRELGVKWTLADAQHAGGVGQVTTLGSDLSVATATTHVGFNI 226 P ++E++ IV IN L ELGV W + + T G ++A+ G Sbjct: 278 PSARIEVALSIVDINADQLTELGVDWRVGIRTGNNHQVVIKTTGDQSNIASN----GALG 333 Query: 227 GRINGRLLDL---ELSALEQKQQLDIIASPRLLASHLQPASIKQGSEIPYQVSSGESGAT 283 ++ R LD ++ LE + +++ P LL A I SE Y +G+ A Sbjct: 334 SLVDARGLDYLLARVNLLENEGSAQVVSRPTLLTQENAQAVIDH-SETYYVKVTGKEVA- 391 Query: 284 SVEFKEAVLG--MEVTPTVLQKG---RIRLKLHISQNVPGQVLQQADGEVLAIDKQEIET 338 E K G + +TP VL +G I L LHI +G + I + ++T Sbjct: 392 --ELKGITYGTMLRMTPRVLTQGDKSEISLNLHIEDGNQKPNSSGIEG-IPTISRTVVDT 448 Query: 339 QVEVKSGETLALGGIFTRKNKSGQDSVPLLGDIPWFGQLFRHDGKEDERRELVVFITPRL 398 V G++L +GGI+ + VPLLGDIP+ G LFR + R + I PR+ Sbjct: 449 VARVGHGQSLIIGGIYRDELSVALSKVPLLGDIPYIGALFRRKSELTRRTVRLFIIEPRI 508 Query: 399 V 399 + Sbjct: 509 I 509 Score = 33.3 bits (76), Expect = 0.002 Identities = 23/116 (19%), Positives = 43/116 (37%), Gaps = 20/116 (17%) Query: 10 KPQKVTLMVDDVPVAQVLQALAEQEKLNLVVSPDVSGTVSLHLTDVPWKQALQTVVKSAG 69 P + + +L +VVS ++ VS + LQ + Sbjct: 32 LPIPYVYVAKGESLRDLLTDFGANYDATVVVSDKINDKVSGQFEHDNPQDFLQHIASLYN 91 Query: 70 LITRQEGNILSVHSIAWQNNNIARQEAEQARAQANLPLENRSITLQYADAGELAKA 125 L+ +GN+L + ++N+ +A +R I LQ ++A EL +A Sbjct: 92 LVWYYDGNVLYI----FKNSEVA----------------SRLIRLQESEAAELKQA 127
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 38.4 bits (89), Expect = 4e-06 Identities = 21/92 (22%), Positives = 34/92 (36%), Gaps = 16/92 (17%) Query: 55 VACIDGDVVGHLTIDVQQRPRRSHVADFGICVDSRWKNRGVASALMREMIE------MCD 108 + ++ + +G + I + + D + D R K GV +AL+ + IE C Sbjct: 69 LYYLENNCIGRIKIR-SNWNGYALIEDIAVAKDYRKK--GVGTALLHKAIEWAKENHFCG 125 Query: 109 NWLRVDRIELTVFVDNAPAIKVYKKYGFEIEG 140 L I N A Y K+ F I Sbjct: 126 LMLETQDI-------NISACHFYAKHHFIIGA 150
>NAFLGMOTY#Sodium-type flagellar protein MotY precursor signature. Length = 293 Score = 31.6 bits (71), Expect = 0.007 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 17/82 (20%) Query: 275 RTPISGDYRGYQVYSMPPPSSGGIHIVQILNI--LENFDMKKYGF-GSADAMQIMAEAEK 331 R P+ G+ R + SMPPP G H +I N+ + FD G+ G A I++E EK Sbjct: 77 RRPM-GETRNVSLISMPPPWRPGEHADRITNLKFFKQFD----GYVGGQTAWGILSELEK 131 Query: 332 YAYADRSEYLGDPDFVKVPWQA 353 Y P F WQ+ Sbjct: 132 GRY---------PTFSYQDWQS 144
>PF04619#Dr-family adhesin Length = 160 Score = 29.5 bits (66), Expect = 0.008 Identities = 12/65 (18%), Positives = 23/65 (35%), Gaps = 4/65 (6%) Query: 29 VGAKYGHKMIEFDAKLSKDGEIFLLHDDNLERTSNGWGVAGELNWQD----LLRVDAGSW 84 +G ++ D + G+ FL+ D+N ++ W + D GSW Sbjct: 70 LGCDARQVALKADTDNFEQGKFFLISDNNRDKLYVNIRPTDNSAWTTDNGVFYKNDVGSW 129 Query: 85 YSKMF 89 + Sbjct: 130 GGIIG 134
>PF05272#Virulence-associated E family protein Length = 892 Score = 32.4 bits (73), Expect = 0.003 Identities = 13/43 (30%), Positives = 20/43 (46%), Gaps = 7/43 (16%) Query: 33 IVMVGPSGCGKSTLLRMVAGLERVTEGDIWINDQRVTEMEPKD 75 +V+ G G GKSTL+ + GL+ + +D KD Sbjct: 599 VVLEGTGGIGKSTLINTLVGLD-------FFSDTHFDIGTGKD 634
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 39.3 bits (91), Expect = 2e-05 Identities = 39/160 (24%), Positives = 66/160 (41%), Gaps = 14/160 (8%) Query: 134 GHLLSQPFNSSTPVLYYNKDAFKKAGLDPEQPPKTWQDLADYAAKLKASGMKCGYASGWQ 193 G L++ P L YNKD PPKTW+++ +LKA G + + Sbjct: 127 GKLIAYPIAVEALSLIYNKDLLP-------NPPKTWEEIPALDKELKAKGKSALMFNLQE 179 Query: 194 GWIQLENFSAWNGLPFASKNNGFDGTDAVLEF--NKPEQVKHIAMLEEMNKKGDFSYVGR 251 + +A G F +N +D D ++ K + +++ + D Y Sbjct: 180 PYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDY--- 236 Query: 252 KDESTEKFYNGDCAMTTASSGSLANIREYAKFNYGVGMMP 291 + F G+ AMT + +NI + +K NYGV ++P Sbjct: 237 -SIAEAAFNKGETAMTINGPWAWSNI-DTSKVNYGVTVLP 274
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 53.5 bits (128), Expect = 1e-09 Identities = 39/181 (21%), Positives = 62/181 (34%), Gaps = 14/181 (7%) Query: 19 EQTPEKETEVQNEQPVVEEI---VQAQEPVKASEQAVEEQPQAHTEAEAETFAADVVEVT 75 TP + TE E E Q+ + + Q E +A + +A T EV Sbjct: 1030 PATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTN---EVA 1086 Query: 76 EQVAESEKAQPEAEVVAQPEPVVEETPEPVAIEREELPLPEDVNAEAVSPEEWQAEAETV 135 + +E+++ Q E E E +E E+ V ++ VSP++ Q+E Sbjct: 1087 QSGSETKETQTT----ETKETATVEKEEKAKVETEKTQEVPKVTSQ-VSPKQEQSETVQP 1141 Query: 136 EIVEAAEEEA---AKEEITDEELETALAAEAAEEAVMVVPPAEEEQPVEEIAQEQEKPTK 192 + A E + KE + A E + V P E V E P Sbjct: 1142 QAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPEN 1201 Query: 193 E 193 Sbjct: 1202 T 1202 Score = 45.4 bits (107), Expect = 4e-07 Identities = 29/157 (18%), Positives = 53/157 (33%), Gaps = 10/157 (6%) Query: 17 QKEQTPEKETEVQNEQPVVEEIVQAQEPVKASE------QAVEEQPQAHTEAEAETFAAD 70 Q +T E T + E+ VE + P S+ Q+ QPQA E + Sbjct: 1096 QTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNI 1155 Query: 71 VVEVTEQVAESEKAQPEAEVVAQPEPVVEETPEPVAIEREELPLPEDVNAEAVSPEEWQA 130 ++ ++ QP E + E V E+ V + PE+ P Sbjct: 1156 KEPQSQTNTTADTEQPAKETSSNVEQPVTES-TTVNTGNSVVENPENTTPATTQP---TV 1211 Query: 131 EAETVEIVEAAEEEAAKEEITDEELETALAAEAAEEA 167 +E+ + + + + E T + + + A Sbjct: 1212 NSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVA 1248 Score = 41.2 bits (96), Expect = 1e-05 Identities = 31/153 (20%), Positives = 57/153 (37%), Gaps = 7/153 (4%) Query: 17 QKEQTPEKETEVQNEQPVVEEIVQAQEPVKASEQAVE-EQPQAHTEAEAETFAADVV--- 72 + ++ P+ ++V +Q E + EP + ++ V ++PQ+ T A+T Sbjct: 1118 KTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSS 1177 Query: 73 EVTEQVAESEKAQPEAEVVAQPEPVVEETPEPVAIEREELPLPEDVNAEAVSPEEWQAEA 132 V + V ES VV PE T +P E P++ + +V E Sbjct: 1178 NVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNS-ESSNKPKNRHRRSVRSVPHNVEP 1236 Query: 133 ETVEIVEAAEEEAAKEEITDEELETALAAEAAE 165 T + A ++T L+ A+ Sbjct: 1237 ATTSSNDR--STVALCDLTSTNTNAVLSDARAK 1267 Score = 38.1 bits (88), Expect = 9e-05 Identities = 29/178 (16%), Positives = 53/178 (29%), Gaps = 7/178 (3%) Query: 17 QKEQTPEKETEVQNEQPVVEEIVQAQEPVKASEQAVEEQPQAHTEAE-AETFAADVVEVT 75 +E E ++ V+ E+ Q+ K ++ ++ + E A+ EV Sbjct: 1065 NREVAKEAKSNVKAN-TQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVP 1123 Query: 76 EQVAESEKAQPEAEVV-AQPEPVVEETPEPVAIEREELPLPEDVNAEAVSP-EEWQAEAE 133 + ++ Q ++E V Q EP E P E + + A+ P +E + E Sbjct: 1124 KVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQS---QTNTTADTEQPAKETSSNVE 1180 Query: 134 TVEIVEAAEEEAAKEEITDEELETALAAEAAEEAVMVVPPAEEEQPVEEIAQEQEKPT 191 E A P + V + E T Sbjct: 1181 QPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPAT 1238 Score = 34.3 bits (78), Expect = 0.001 Identities = 30/144 (20%), Positives = 50/144 (34%), Gaps = 9/144 (6%) Query: 52 VEEQPQAHTEAEAETFAADVVEVT-EQVAESEKAQPEAEVVAQPEPVVE-ETPEPVAIER 109 VE++ Q T +V E A+ + V P P ET E VA Sbjct: 985 VEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENS 1044 Query: 110 EELPLPEDVNAEAVSPEEWQAEAETVEIVEAAEEEAAKEEITDEELETALAAEAAEEAVM 169 ++ ++ V E A T + E A+E + + + E A + +E Sbjct: 1045 KQ-------ESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQT 1097 Query: 170 VVPPAEEEQPVEEIAQEQEKPTKE 193 EE A+ + + T+E Sbjct: 1098 TETKETATVEKEEKAKVETEKTQE 1121
>SHIGARICIN#Ribosome inactivating protein family signature. Length = 289 Score = 25.9 bits (57), Expect = 0.042 Identities = 6/21 (28%), Positives = 13/21 (61%) Query: 7 FFIVIIGLIVVAASFRFMQQR 27 +V+I AA ++F++Q+ Sbjct: 173 ALMVLIQSTSEAARYKFIEQQ 193
>PF01206#SirA family protein Length = 76 Score = 105 bits (265), Expect = 3e-34 Identities = 24/72 (33%), Positives = 41/72 (56%) Query: 9 DHTLDALGLRCPEPVMMVRKTVRNMQPGETLLIIADDPATTRDIPGFCTFMEHELVAKET 68 D +LDA GL CP P++ +KT+ M GE L ++A DP + +D F HEL+ ++ Sbjct: 5 DQSLDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKE 64 Query: 69 DGLPYRYLIRKG 80 + Y + +++ Sbjct: 65 EDGTYHFRLKRA 76
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 56.0 bits (135), Expect = 9e-11 Identities = 80/398 (20%), Positives = 147/398 (36%), Gaps = 32/398 (8%) Query: 24 LRLNLRIVSIVMFNFASYLTIGLPLAVLPGYVHDVM--GFSAFWAGLVISLQYFATLLSR 81 ++ N ++ I+ + IGL + VLPG + D++ G++++L Sbjct: 1 MKPNRPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACA 60 Query: 82 PHAGRYADSLGPKKIVVFGLCGCFLSGLGYLTAGLTASLPVISLLLLCLGRVILGI-GQS 140 P G +D G + +++ L G + + Y L V L +GR++ GI G + Sbjct: 61 PVLGALSDRFGRRPVLLVSLAG---AAVDYAIMATAPFLWV-----LYIGRIVAGITGAT 112 Query: 141 FAGTGSTLWGVGVVGSL--HIGRVISWNGIVTYGAMAMGAPLGVVFYHWGGLQALALIIM 198 A G+ + + H G + + G +G +G H A AL + Sbjct: 113 GAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGL 172 Query: 199 GVALVAILLAIPRPTVK--ASKGKPLPFRAVLGRVWLYGMALALA-----SAGFGVIATF 251 LL + + P + + +A +A V A Sbjct: 173 NFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAAL 232 Query: 252 ITLFYDAK-GWDGAAFALTLFSCAFVGT---RLLFPNGINRIGGLNVAMICFSVEIIGLL 307 +F + + WD ++L + + + ++ R+G M+ + G + Sbjct: 233 WVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYI 292 Query: 308 LVGVATMPWMAKIG-VLLAGAGFSLVFPALGVVAVKAVPQQNQGAALATYTVFMDLSLGV 366 L+ AT WMA VLLA G + PAL + + V ++ QG + L+ + Sbjct: 293 LLAFATRGWMAFPIMVLLASGGIGM--PALQAMLSRQVDEERQGQLQGSLAALTSLT-SI 349 Query: 367 TGPLAGLVMSWAGVPV----IYLAAAGLVAIALLLTWR 400 GPL + A + ++A A L + L R Sbjct: 350 VGPLLFTAIYAASITTWNGWAWIAGAALYLLCLPALRR 387
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.020 Identities = 10/34 (29%), Positives = 19/34 (55%) Query: 25 QAVLNNVSLTLKSGETVALLGRSGCGKSTLARLL 58 Q + ++ +++ T+ + G SG GK +AR L Sbjct: 147 QEIYRVLARLMQTDLTLMITGESGTGKELVARAL 180
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 49.9 bits (119), Expect = 5e-09 Identities = 41/171 (23%), Positives = 73/171 (42%), Gaps = 7/171 (4%) Query: 200 REREHGTVEHLLVMPITPFEIMMAKI-WSMGLVVLVVSGLSLVLMVKGVLGVPIEGSIPL 258 R T E +L + +I++ ++ W+ L +G+ +V G + L Sbjct: 93 RMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAGIGVVAAALGY----TQWLSLL 148 Query: 259 FMLGV-ALSLFATTSIGIFMGTIARSMPQLGLLVILVLLPLQMLSGGSTPRESMPQMVQD 317 + L V AL+ A S+G+ + +A S LV+ P+ LSG P + +P + Q Sbjct: 149 YALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQT 208 Query: 318 IMLTMPTTHFVSLAQAILYRGAGFEIVWPQFLTLMAIGGAFF-TIALLRFR 367 +P +H + L + I+ ++ + I FF + ALLR R Sbjct: 209 AARFLPLSHSIDLIRPIMLGHPVVDVCQHVGALCIYIVIPFFLSTALLRRR 259
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.045 Identities = 9/26 (34%), Positives = 14/26 (53%) Query: 37 ARCMVGLIGPDGVGKSSLLSLISGAR 62 V L G G+GKS+L++ + G Sbjct: 595 FDYSVVLEGTGGIGKSTLINTLVGLD 620
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 84.1 bits (208), Expect = 5e-20 Identities = 73/409 (17%), Positives = 142/409 (34%), Gaps = 83/409 (20%) Query: 6 RHLAWWVVGLLAVAAIVVWWLLRPAGVPEGFAVSNGRI--EATEVDIASKIAGRIDTILV 63 R +A++++G L +A + +L E A +NG++ +I + I+V Sbjct: 58 RLVAYFIMGFLVIA--FILSVLGQV---EIVATANGKLTHSGRSKEIKPIENSIVKEIIV 112 Query: 64 KEGQFVREGEVLAKMDTRV----------------LQEQRLEAI---------------- 91 KEG+ VR+G+VL K+ L++ R + + Sbjct: 113 KEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPD 172 Query: 92 --------------------AQIKEAQSAVAAAQALLEQRQSETRAAQSLVNQRQAELDS 131 Q Q+ + L+++++E + +N+ + Sbjct: 173 EPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRV 232 Query: 132 VAKRHTRSRSLAQRGAISAQQLDDDRAAAESARAALESAKAQVSASKAAIEAARTNIIQ- 190 R SL + AI+ + + A L K+Q+ ++ I +A+ Sbjct: 233 EKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLV 292 Query: 191 ------------AQTRVEAAQATERRIAADID--DSELKAPRDGRV-QYRVAEPGEVLAA 235 QT T + S ++AP +V Q +V G V+ Sbjct: 293 TQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTT 352 Query: 236 GGRVLNMVDLSDVY-MTFFLPTEQAGTLKLGGEARLILDAAPDLRIPATISFVASVAQFT 294 ++ +V D +T + + G + +G A + ++A P R V V Sbjct: 353 AETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYG---YLVGKVKNIN 409 Query: 295 PKTVETSDERLKLMFRVKARIPPELLQQHLEYV--KTGLPGVAWVRVNE 341 +E D+RL L+F V I L + + +G+ A ++ Sbjct: 410 LDAIE--DQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGM 456
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 51.0 bits (122), Expect = 4e-09 Identities = 41/218 (18%), Positives = 70/218 (32%), Gaps = 33/218 (15%) Query: 97 LQAELNSAKGSLAKALSTASNARITFNRQASLLKTNYVSR-QDYDT-ARTQLNEAEANVT 154 + + A L S + K Y Q + +L + N+ Sbjct: 257 QENKYVEAVNELRVYKSQLEQIE----SEILSAKEEYQLVTQLFKNEILDKLRQTTDNIG 312 Query: 155 VAKAAVEQATINLQYANVTSPITGVSGKSSV-TVGALVTANQADSLVTVQRLDPIYVDLT 213 + + + Q + + +P++ + V T G +VT + +V V D + V Sbjct: 313 LLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAET-LMVIVPEDDTLEVTAL 371 Query: 214 QSVQDFLRMKEEVASGQIKQVQGSTPVQLNLE--NGKRY-SQTGTLK--FSDPTVDETTG 268 +D I + + +E RY G +K D D+ G Sbjct: 372 VQNKD------------IGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLG 419 Query: 269 SVT--LRAI------FPNPNGDLLPGMYVTALVDEGSR 298 V + +I N N L GM VTA + G R Sbjct: 420 LVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGMR 457 Score = 32.1 bits (73), Expect = 0.004 Identities = 25/118 (21%), Positives = 47/118 (39%), Gaps = 7/118 (5%) Query: 53 PGRTVPY-EVAEIRPQVGGIIIKRNFI-EGDKVNQGDSLYQIDPAPLQAELNSAKGSLAK 110 G+ EI+P I+ K + EG+ V +GD L ++ +A+ + SL + Sbjct: 87 NGKLTHSGRSKEIKPIENSIV-KEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQ 145 Query: 111 ALSTASNARITFNRQASLLKTNYVSRQDYDTARTQLNEAEANVTVAKAAVEQATINLQ 168 A + +I +R L K + D + N +E V + +++ Q Sbjct: 146 ARLEQTRYQIL-SRSIELNKLPELKLPDEPYFQ---NVSEEEVLRLTSLIKEQFSTWQ 199
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1292 bits (3345), Expect = 0.0 Identities = 723/1032 (70%), Positives = 845/1032 (81%), Gaps = 1/1032 (0%) Query: 1 MANYFIDRPVFAWVLAIIMMLAGGLAIMNLPVAQYPQIAPPTITVSATYPGADAQTVEDS 60 MAN+FI RP+FAWVLAII+M+AG LAI+ LPVAQYP IAPP ++VSA YPGADAQTV+D+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQVIEQNMNGLDGLMYMSSTSDAAGNASITLTFETGTSPDIAQVQVQNKLQLAMPSLPE 120 VTQVIEQNMNG+D LMYMSSTSD+AG+ +ITLTF++GT PDIAQVQVQNKLQLA P LP+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 AVQQQGISVDKSSSNILMVAAFISDNGSLNQYDIADYVASNIKDPLSRTAGVGSVQLFGS 180 VQQQGISV+KSSS+ LMVA F+SDN Q DI+DYVASN+KD LSR GVG VQLFG+ Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 EYAMRIWLDPQKLNKYNLVPSDVISQIKVQNNQISGGQLGGMPQAADQQLNASIIVQTRL 240 +YAMRIWLD LNKY L P DVI+Q+KVQN+QI+ GQLGG P QQLNASII QTR Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 QTPEEFGKILLKVQQDGSQVLLRDVARVELGAEDYSTVARYNGKPAAGIAIKLAAGANAL 300 + PEEFGK+ L+V DGS V L+DVARVELG E+Y+ +AR NGKPAAG+ IKLA GANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 DTSRAVKEELNRLSAYFPASLKTVYPYDTTPFIEISIQEVFKTLVEAIILVFLVMYLFLQ 360 DT++A+K +L L +FP +K +YPYDTTPF+++SI EV KTL EAI+LVFLVMYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NFRATIIPTIAVPVVILGTFAILSAVGFTINTLTMFGMVLAIGLLVDDAIVVVENVERVI 420 N RAT+IPTIAVPVV+LGTFAIL+A G++INTLTMFGMVLAIGLLVDDAIVVVENVERV+ Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 AEDKLPPKEATHKSMGQIQRALVGIAVVLSAVFMPMAFMSGATGEIYRQFSITLISSMLL 480 EDKLPPKEAT KSM QIQ ALVGIA+VLSAVF+PMAF G+TG IYRQFSIT++S+M L Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVFVAMSLTPALCATILKAAPEGGHK-PNALFARFNTLFEKSTQHYTDSTRSLLRCTGRY 539 SV VA+ LTPALCAT+LK H+ F FNT F+ S HYT+S +L TGRY Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 Query: 540 MVVYLLICAGMAVLFLRTPTSFLPEEDQGVFMTTAQLPSGATMVNTTKVLQQVTDYYLTK 599 +++Y LI AGM VLFLR P+SFLPEEDQGVF+T QLP+GAT T KVL QVTDYYL Sbjct: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 Query: 600 EKDNVQSVFTVGGFGFSGQGQNNGLAFISLKPWSERVGEENSVTAIIQRAMIALSSINKA 659 EK NV+SVFTV GF FSGQ QN G+AF+SLKPW ER G+ENS A+I RA + L I Sbjct: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG 660 Query: 660 VVFPFNLPAVAELGTASGFDMELLDNGNLGHEKLTQARNELLSLAAQSPNQVTGVRPNGL 719 V PFN+PA+ ELGTA+GFD EL+D LGH+ LTQARN+LL +AAQ P + VRPNGL Sbjct: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 Query: 720 EDTPMFKVNVNAAKAEAMGVALSDINQTISTAFGSSYVNDFLNQGRVKKVYVQAGTPFRM 779 EDT FK+ V+ KA+A+GV+LSDINQTISTA G +YVNDF+++GRVKK+YVQA FRM Sbjct: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM 780 Query: 780 LPDNINQWYVRNASGTMAPLSAYSSTEWTYGSPRLERYNGIPSMEILGEAAAGKSTGDAM 839 LP+++++ YVR+A+G M P SA++++ W YGSPRLERYNG+PSMEI GEAA G S+GDAM Sbjct: 781 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM 840 Query: 840 KFMADLVAKLPAGVGYSWTGLSYQEALSSNQAPALYAISLVVVFLALAALYESWSIPFSV 899 M +L +KLPAG+GY WTG+SYQE LS NQAPAL AIS VVVFL LAALYESWSIP SV Sbjct: 841 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900 Query: 900 MLVVPLGVVGALLATDLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAVEMMQKEGKTPI 959 MLVVPLG+VG LLA L NDVYF VGLLTTIGLSAKNAILIVEFA ++M+KEGK + Sbjct: 901 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV 960 Query: 960 EAIIEAARMRLRPILMTSLAFILGVLPLVISHGAGSGAQNAVGTGVMGGMFAATVLAIYF 1019 EA + A RMRLRPILMTSLAFILGVLPL IS+GAGSGAQNAVG GVMGGM +AT+LAI+F Sbjct: 961 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF 1020 Query: 1020 VPVFFVVVEHLF 1031 VPVFFVV+ F Sbjct: 1021 VPVFFVVIRRCF 1032
>HOKGEFTOXIC#Hok/Gef cell toxic protein family signature. Length = 52 Score = 65.2 bits (159), Expect = 8e-19 Identities = 17/50 (34%), Positives = 32/50 (64%) Query: 1 MPQKYRLLSLIVICFTLLFFTWMIRDSLCELHIKQESYELAAFLACKLKE 50 +P+ + ++++C TLL FT++ R SLCE+ + E+AAF+A + + Sbjct: 3 LPRSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYESGK 52
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 27.5 bits (61), Expect = 0.017 Identities = 19/66 (28%), Positives = 26/66 (39%), Gaps = 1/66 (1%) Query: 77 MTCLTVFIISVALLMVGLWNATLLLSEKGFYGLAFFLSLFGAVAVQKNIRDAGINPPKET 136 MT T II LL L + + GLA FL+ F V I P E Sbjct: 61 MTSFTRIIIVFGLLRNALGTPSAP-PNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEE 119 Query: 137 QVTQEE 142 +++ +E Sbjct: 120 KISMQE 125
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 102 bits (257), Expect = 2e-27 Identities = 76/348 (21%), Positives = 127/348 (36%), Gaps = 67/348 (19%) Query: 2 IIVTGGAGFIGSNIVKALNDKGITDILVVDNLKD--------------GTKFVNLVDLNI 47 +VTG AGFIG ++ K L + G ++ +DNL D +++ Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAG-HQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 48 ADYMDKEDFLIQIMAGEEFGDVEAIFHEGACSSTTEWDGKYMMDNNYQYSK-------EL 100 AD + + + A F E +F + +Y ++N + Y+ + Sbjct: 62 ADR----EGMTDLFASGHF---ERVFISPHRLAV-----RYSLENPHAYADSNLTGFLNI 109 Query: 101 LHYCLEREIP-FLYASSAATYGGRTSD-FIESREYEKPLNVYGYSKFLFDEYVRQILPEA 158 L C +I LYASS++ YG F + P+++Y +K + Sbjct: 110 LEGCRHNKIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLY 169 Query: 159 NSQIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVA 218 G R+F VYGP + MA F + G+S ++ KRDF Y+ D+A Sbjct: 170 GLPATGLRFFTVYGPWG--RPDMA--LFKFTKAMLEGKSIDVY-NYGKMKRDFTYIDDIA 224 Query: 219 DVNL------------WFLENGVSG-------IFNLGTGRAESFQAVADATLAY-HKKGQ 258 + + W +E G ++N+G A + + Sbjct: 225 EAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAK 284 Query: 259 IEYIPFPDKLKGRYQAFTQADLTNLRAA-GYDKPFKTVAEGVTEYMAW 305 +P G T AD L G+ P TV +GV ++ W Sbjct: 285 KNMLPLQ---PGDVL-ETSADTKALYEVIGF-TPETTVKDGVKNFVNW 327
>SECA#SecA protein signature. Length = 901 Score = 41.8 bits (98), Expect = 9e-06 Identities = 38/129 (29%), Positives = 56/129 (43%), Gaps = 18/129 (13%) Query: 233 NLSMLALRAGAQRFHAQPLSANDTLKNKLLAALPFKPTGAQARVVAEIEHDM-ALDVPMM 291 LS L+ F A+ L + L+N + A A R ++ M DV ++ Sbjct: 37 KLSDEELKGKTAEFRAR-LEKGEVLENLIPEAF------AVVREASKRVFGMRHFDVQLL 89 Query: 292 ---RLVQGDV-----GSGKTLVAALAA-LRAIAHGKQVALMAPTELLAEQHANNFRNWFA 342 L + + G GKTL A L A L A+ GK V ++ + LA++ A N R F Sbjct: 90 GGMVLNERCIAEMRTGEGKTLTATLPAYLNALT-GKGVHVVTVNDYLAQRDAENNRPLFE 148 Query: 343 PLGIKVGWL 351 LG+ VG Sbjct: 149 FLGLTVGIN 157
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.0 bits (91), Expect = 2e-05 Identities = 71/391 (18%), Positives = 130/391 (33%), Gaps = 33/391 (8%) Query: 20 LLVAFLTSIAGALQTPTLSIFLADELKARPIM--VGFFFTGSAIMGILVSQFLARHSDKQ 77 L L ++ L P L L D + + + G A+M + L SD+ Sbjct: 11 LSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRF 70 Query: 78 GDRKLLILLCCLFGVLACTLFAWNRNYFILLSTGVLLSSFASTANPQMFALAREHADRTG 137 G R ++L+ + + A ++L ++ A AD T Sbjct: 71 GRR-PVLLVSLAGAAVDYAIMATAPFLWVLYIGRIV----AGITGATGAVAGAYIADITD 125 Query: 138 RET-VMFSTFLRAQISLAWVIGPPLAYELAMGFSFKVMYLTAAIAFVVCGLIVWLFLP-- 194 + F+ A V GP L + GFS + AA + L LP Sbjct: 126 GDERARHFGFMSACFGFGMVAGPVLGGLMG-GFSPHAPFFAAAALNGLNFLTGCFLLPES 184 Query: 195 --SIQRNIPVVT-QPVEILPSTHRKRDTRLLFVVCSMMWAANNLYMINMPLFIIDELHLT 251 +R + P+ L V +M + +F D H Sbjct: 185 HKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWD 244 Query: 252 DKLAGEMI-GIAAGLEIPMMLIAGYYMKRIGKRLLMLIAIVSGMCFYASVLMATTPAVEL 310 G + + +I G R+G+R +++ +++ Y +L+A + Sbjct: 245 ATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGY--ILLAFATRGWM 302 Query: 311 ELQILNAIFLGILCGIGMLYFQDLMPEKI---------GSATTLYANTSRVGWIIAGSVD 361 + L GIGM Q ++ ++ GS L + TS VG ++ ++ Sbjct: 303 ---AFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIY 359 Query: 362 GIMVEIWSYHALFWLAIGMLGIAMICLLFIK 392 + W+ W I + ++CL ++ Sbjct: 360 AASITTWNG----WAWIAGAALYLLCLPALR 386 Score = 33.3 bits (76), Expect = 0.002 Identities = 18/102 (17%), Positives = 34/102 (33%) Query: 17 AAFLLVAFLTSIAGALQTPTLSIFLADELKARPIMVGFFFTGSAIMGILVSQFLARHSDK 76 AA + V F+ + G + IF D +G I+ L + Sbjct: 213 AALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAA 272 Query: 77 QGDRKLLILLCCLFGVLACTLFAWNRNYFILLSTGVLLSSFA 118 + + ++L + L A+ ++ VLL+S Sbjct: 273 RLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGG 314
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 38.3 bits (89), Expect = 4e-05 Identities = 33/208 (15%), Positives = 71/208 (34%), Gaps = 13/208 (6%) Query: 49 IIVEFLPVSLLTP----MAQDLGISEGVA---GQSVTVTAFVAMFASLFITQTIQATDRR 101 + ++ + + L+ P + +DL S V G + + A + + + RR Sbjct: 14 VALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRR 73 Query: 102 YVVILFAVLLTLSCLLVSFANSFSLLLIGRACLGLALGGFWAMSASLTMRLVPPRTVPKA 161 V+++ + +++ A +L IGR G+ G A++ + + + Sbjct: 74 PVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGIT-GATGAVAGAYIADITDGDERARH 132 Query: 162 LSVIFGAVSIALVIAAPLGSFLGELIGWRNVFNAAAVMG----VLCIFWIIKSLPSLPGE 217 + +V LG +G F AAA + + F + +S Sbjct: 133 FGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRP 191 Query: 218 PSHQKQNTFRLLQRPGVMAGMIAIFMSF 245 + N + M + A+ F Sbjct: 192 LRREALNPLASFRWARGMTVVAALMAVF 219
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 38.2 bits (89), Expect = 9e-05 Identities = 28/105 (26%), Positives = 41/105 (39%), Gaps = 17/105 (16%) Query: 22 AVSRGDAVADYIIDNVSILDLINGGEISGPIVIKGRYIAGVG----------AEYTDAPA 71 V+R D +I N ILD + G + I +K IA +G P Sbjct: 60 QVTREGGAVDTVITNALILD--HWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPG 117 Query: 72 LQRIDARGATAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVI 116 + I G G +D+H+H + P E A L GLT ++ Sbjct: 118 TEVIAGEGKIVTAGGMDSHIH----FICPQQIEEA-LMSGLTCML 157
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 34.1 bits (78), Expect = 0.001 Identities = 28/168 (16%), Positives = 61/168 (36%), Gaps = 17/168 (10%) Query: 49 FNIAQNDMISTYGLSMTQLGMIGLGFSITYGVGKTLVSYYADGKNTKQFLPFMLILSAIC 108 N++ D+ + + + F +T+ +G + +D K+ L F +I++ C Sbjct: 33 LNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIIN--C 90 Query: 109 MLGFSASMGSGSVSLFLMIAFYALSGFFQSTGGSCSYSTI----TKWTPRRKRGTFLGFW 164 +G SL +M + F Q G + + + ++ P+ RG G Sbjct: 91 FGSVIGFVGHSFFSLLIM------ARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLI 144 Query: 165 NISHNLGGAGAAGVALFGANYLFDGHVIGMFIFPSIIALIVGFIGLRY 212 +G + A+Y+ + + + P + I+ L Sbjct: 145 GSIVAMGEGVGPAIGGMIAHYIHWSY---LLLIP--MITIITVPFLMK 187
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 40.6 bits (95), Expect = 9e-06 Identities = 65/408 (15%), Positives = 137/408 (33%), Gaps = 60/408 (14%) Query: 29 RHILLTIWLGYALFY--FTRKSFNAAVPEILANGVLSRSDIGLLATLFYITYGVSKFVSG 86 RH + IWL F+ N ++P+I + + + T F +T+ + V G Sbjct: 11 RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYG 70 Query: 87 IVSDRSNARYFMGIGLIATGIINILFGFSTSLWAFAVLWVLNAFFQGWGS---PVCARLL 143 +SD+ + + G+I +++ S F L ++ F QG G+ P ++ Sbjct: 71 KLSDQLGIKRLLLFGIIINCFGSVIGFVGHS---FFSLLIMARFIQGAGAAAFPALVMVV 127 Query: 144 TAWY-SRTERGGWWALWNTAHNVGGALIPIVMAAAALHYGWRAGMMIAGCMAIVVGIFLC 202 A Y + RG + L + +G + P + A + W ++ M ++ + Sbjct: 128 VARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHW--SYLLLIPMITIITVPF- 184 Query: 203 WRLRDRPQALGLPAVGEWRHDALEIAQQQEGAGLTRKEILTKYVLLNPYIWLLSFCYVLV 262 + L +I G L I+ + Y VL Sbjct: 185 --------LMKLLKKEVRIKGHFDIK----GIILMSVGIVFFMLFTTSYSISFLIVSVLS 232 Query: 263 YVV-----RAAINDWGNLYMSETLGVDLVTANTAVTMFELGGFI-----------GALVA 306 +++ R + + + + + + + + + GF+ A Sbjct: 233 FLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTA 292 Query: 307 GWGSDKLFNGNRGPMNLIFAAGILL-SVGSLWLMPFASYVMQATCFFTIGFFVFGPQMLI 365 GS +F G + + GIL+ G L+++ + + F T F + + Sbjct: 293 EIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFL-SVSFLTASFLLETTSWFM 351 Query: 366 ---------GMAAAECS---------HKEAAGAATGFVGLFAYLGASL 395 G++ + ++ AGA + ++L Sbjct: 352 TIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGT 399
>PF06580#Sensor histidine kinase Length = 349 Score = 39.8 bits (93), Expect = 2e-05 Identities = 28/142 (19%), Positives = 56/142 (39%), Gaps = 11/142 (7%) Query: 365 LRPRQLDDLTLEQAIRSLMREMELEGRGIVSHLEWRIDESALSENQRVTLFRVCQEGLNN 424 LR ++L + + ++L L++ + + +V + Q + N Sbjct: 208 LRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPM-LVQTLVEN 266 Query: 425 IVKHA-----DASAVTLQGWQQDERLMLVIEDDGSGLPPGSGQ-QGFGLTGMRERVTALG 478 +KH + L+G + + + L +E+ GS + + G GL +RER+ L Sbjct: 267 GIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQMLY 326 Query: 479 G---TLHISCLHG-TRVSVSLP 496 G + +S G V +P Sbjct: 327 GTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 61.4 bits (149), Expect = 2e-13 Identities = 29/174 (16%), Positives = 59/174 (33%), Gaps = 20/174 (11%) Query: 2 ITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDIS 61 T+ + DD +R+ Q L V + + + + D+ MPD + Sbjct: 4 ATILVADDDAAIRTVLNQALSRA-GYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 62 GLELLSQLPK---GMATIMLSVHDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATG 118 +LL ++ K + +++S ++ +A GA +L K ELI + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR---- 117 Query: 119 GCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQG---MAVKEIAAELGLSPKTV 169 A+ R L + + + + + A L + T+ Sbjct: 118 --------ALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTL 163
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 29.2 bits (65), Expect = 0.048 Identities = 23/80 (28%), Positives = 31/80 (38%), Gaps = 10/80 (12%) Query: 367 LGDAEIGDNVNIGAGTITCNYDGANKFKTIIGDDVFVGSDTQLVAPVTVGKGATIAAGTT 426 LGD + D V + AG+ N G DV T G AT A T Sbjct: 616 LGDGD--DKVFLSAGSA--NIYAGK------GHDVVYYDKTDTGYLTIDGTKATEAGNYT 665 Query: 427 VTRNVGENALAISRVPQTQK 446 VTR +G + + V + Q+ Sbjct: 666 VTRVLGGDVKVLQEVVKEQE 685
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 27.3 bits (60), Expect = 0.028 Identities = 20/101 (19%), Positives = 37/101 (36%), Gaps = 18/101 (17%) Query: 31 AAIEKRQKEIADGLASAERAHKDLDLAKASATDQLKKAKAEAQVIIEQ--ANKRRSQILD 88 +EK +++ + A K+ + T + A++ ++ Q K + + Sbjct: 1049 KTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEK 1108 Query: 89 EAKAEAEQERTKIVA----------------QAQAEIEAER 113 E KA+ E E+T+ V Q QAE E Sbjct: 1109 EEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPAREN 1149
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 34.8 bits (80), Expect = 7e-04 Identities = 38/196 (19%), Positives = 62/196 (31%), Gaps = 51/196 (26%) Query: 170 KHALERPKPTDAVSRALQHDLSDVIGQEQG----KRGLEITAAGGHNILLIGPPGTGKTM 225 AL PK + D ++G+ R L +++ G GTGK + Sbjct: 116 GRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKEL 175 Query: 226 LASRINGLLPDLSNEEALESAAILSLVNAESVQKQWRQRPFRSPHHSA--------SLTA 277 +A ++ R PF + + +A L Sbjct: 176 VARALHDYGK-------------------------RRNGPFVAINMAAIPRDLIESELFG 210 Query: 278 MVGG---GAIP-GPGEISLAHNGVLFLDEL----PEFERRTLDALREPIESGQIHLSRTR 329 G GA G A G LFLDE+ + + R L L++ G+ Sbjct: 211 HEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQ----GEYT--TVG 264 Query: 330 AKITYPARFQLVAAMN 345 + + ++VAA N Sbjct: 265 GRTPIRSDVRIVAATN 280
>SECA#SecA protein signature. Length = 901 Score = 30.2 bits (68), Expect = 0.004 Identities = 11/71 (15%), Positives = 30/71 (42%) Query: 14 AKARRKTREELDQEARDRKRQKKRRGHAPGSRAAGGNTTSGSKGQNAPKDPRIGSKTPIP 73 +K + + EE+++ + R+ + +R ++ + + + ++G P P Sbjct: 827 SKVQVRMPEEVEELEQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCP 886 Query: 74 LGVTEKVTKQH 84 G +K + H Sbjct: 887 CGSGKKYKQCH 897
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 602 bits (1553), Expect = 0.0 Identities = 206/478 (43%), Positives = 300/478 (62%), Gaps = 11/478 (2%) Query: 1 MQRGIVWVVDDDSSIRWVLERALAGAGLTCTTFENGAEVLEALASKTPDVLLSDIRMPGM 60 M + V DDD++IR VL +AL+ AG N A + +A+ D++++D+ MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 DGLALLKQIKQRHPMLPVIIMTAHSDLDAAVSAYQQGAFDYLPKPFDIDEAVALVERAIS 120 + LL +IK+ P LPV++M+A + A+ A ++GA+DYLPKPFD+ E + ++ RA++ Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 121 HYQEQQQPRNVQLNGPTTDIIGEAPAMQDVFRIIGRLSRSSISVLINGESGTGKELVAHA 180 + + ++G + AMQ+++R++ RL ++ ++++I GESGTGKELVA A Sbjct: 121 EPKRRPSKLEDDSQDGM-PLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARA 179 Query: 181 LHRHSPRAKAPFIALNMAAIPKDLIESELFGHEKGAFTGANTIRQGRFEQADGGTLFLDE 240 LH + R PF+A+NMAAIP+DLIESELFGHEKGAFTGA T GRFEQA+GGTLFLDE Sbjct: 180 LHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDE 239 Query: 241 IGDMPLDVQTRLLRVLADGQFYRVGGYAPVKVDVRIIAATHQNLEQRVQEGKFREDLFHR 300 IGDMP+D QTRLLRVL G++ VGG P++ DVRI+AAT+++L+Q + +G FREDL++R Sbjct: 240 IGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYR 299 Query: 301 LNVIRVHLPPLRERREDIPRLARHFLQVAARELGVEAKLLHPETEAALTRLAWPGNVRQL 360 LNV+ + LPPLR+R EDIP L RHF+Q A +E G++ K E + WPGNVR+L Sbjct: 300 LNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKE-GLDVKRFDQEALELMKAHPWPGNVREL 358 Query: 361 ENTCRWLTVMAAGQEVLIQDLPGELFESTVAESTSQMQPDSWATLLAQWADRALRS---- 416 EN R LT + + + + EL + S + ++Q + +R Sbjct: 359 ENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFAS 418 Query: 417 -----GHQNLLSEAQPELERTLLTTALRHTQGHKQEAARLLGWGRNTLTRKLKELGME 469 L E+E L+ AL T+G++ +AA LLG RNTL +K++ELG+ Sbjct: 419 FGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>PF06580#Sensor histidine kinase Length = 349 Score = 28.3 bits (63), Expect = 0.042 Identities = 34/190 (17%), Positives = 72/190 (37%), Gaps = 41/190 (21%) Query: 171 IIEQADRLRNLVDRL---LGPQLPGTRVTE-SIHKVAERV---VTLVSMELPDNVRLIRD 223 I+E + R ++ L + L + + S+ V + L S++ D ++ Sbjct: 186 ILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQ 245 Query: 224 YDPSLPELAHDPDQIEQVLLN-IVRNALQ---ALGPEGGEIILRTRTAFQLTLHGERYRL 279 +P++ ++ Q+ +L+ +V N ++ A P+GG+I+L+ Sbjct: 246 INPAIMDV-----QVPPMLVQTLVENGIKHGIAQLPQGGKILLKGT------KDNGTVT- 293 Query: 280 AARIDVEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIARNLIDQHSGK---IEFTSWP 336 ++VE+ G + ++ TG GL R + G I+ + Sbjct: 294 ---LEVENTGSLALKNTKE------------STGTGLQNVRERLQMLYGTEAQIKLSEKQ 338 Query: 337 GHTEFSVYLP 346 G V +P Sbjct: 339 GKVNAMVLIP 348
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 180 bits (458), Expect = 4e-51 Identities = 97/445 (21%), Positives = 170/445 (38%), Gaps = 81/445 (18%) Query: 4 KLRNIAIIAHVDHGKTTLVDKLLQQSGTFDSRAETQE--RVMDSNDLEKERGITILAKNT 61 K+ NI ++AHVD GKTTL + LL SG + D+ LE++RGITI T Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 62 AIKWNDYRINIVDTPGHADFGGEVERVMSMVDSVLLVVDAFDGPMPQTRFVTKKAFAYGL 121 + +W + ++NI+DTPGH DF EV R +S++D +L++ A DG QTR + G+ Sbjct: 62 SFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGI 121 Query: 122 KPIVVINKVDRPGARPDWVVDQVFD-------------LFVNLDATDEQLD--------- 159 I INK+D+ G V + + L+ N+ T+ Sbjct: 122 PTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEG 181 Query: 160 --------------------------------FPIVYASALNGIAGLDHEDMAEDMTPLY 187 FP+ + SA N I G+D+ L Sbjct: 182 NDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNI-GIDN---------LI 231 Query: 188 QAIVDHVPAPDVDLDGPFQMQISQLDYNSYVGVIGIGRIKRGKVKPNQQVTIIDSEGKTR 247 + I + + ++ +++Y+ + R+ G + V I + E Sbjct: 232 EVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKI-- 289 Query: 248 NAKVGKVLGHLGLERIETDLAEAGDIVAITGLGELNISDTVCDTQNVEALPALSVDEPTV 307 K+ ++ + E + D A +G+IV + L ++ + DT+ + + P + Sbjct: 290 --KITEMYTSINGELCKIDKAYSGEIVILQNEF-LKLNSVLGDTKLLPQRERIENPLPLL 346 Query: 308 SMFFCVNTSPFCGKEGKFVTSRQILDRLNKELVHNVALRVEETEDADAFRVSGRGELHLS 367 + + D L LR +S G++ + Sbjct: 347 QTTVEPSKPQQREMLLDALLEISDSDPL---------LRYYVDSATHEIILSFLGKVQME 397 Query: 368 VLIENMRRE-GFELAVSRPKVIFRE 391 V ++ + E+ + P VI+ E Sbjct: 398 VTCALLQEKYHVEIEIKEPTVIYME 422 Score = 32.5 bits (74), Expect = 0.005 Identities = 13/75 (17%), Positives = 29/75 (38%), Gaps = 1/75 (1%) Query: 398 EPYENVTLDVEEQHQGSVMQALGERKGDLKNMNPDGKGRVRLDYVIPSRGLIGFRSEFMT 457 EPY + + +++ + ++ + V L IP+R + +RS+ Sbjct: 537 EPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKN-NEVILSGEIPARCIQEYRSDLTF 595 Query: 458 MTSGTGLLYSTFSHY 472 T+G + + Y Sbjct: 596 FTNGRSVCLTELKGY 610
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 29.5 bits (66), Expect = 0.028 Identities = 31/161 (19%), Positives = 64/161 (39%), Gaps = 15/161 (9%) Query: 227 NVFFVYAVYCGLTFFIPFLKNIYLLP----------VALVGAYGIINQYCLKMIGGPIGG 276 N+ F+ V CG F + ++P A +G+ I +I G IGG Sbjct: 255 NIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGG 314 Query: 277 MISDKILKSPSKYLCYTFIISTAALVLLIMLPHESMPVYLGMACTLGFGAIVFTQRAVFF 336 ++ D+ + P L + + + L E+ ++ + G + FT+ Sbjct: 315 ILVDR--RGPLYVLNIGVTFLSVSFLTASFLL-ETTSWFMTIIIVFVLGGLSFTK--TVI 369 Query: 337 APIGEAKIAENKTGAAMALGSFIGYAPAMFCFSLYGYILDL 377 + I + + + + GA M+L +F + ++ G +L + Sbjct: 370 STIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSI 410
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 92.2 bits (229), Expect = 9e-24 Identities = 35/117 (29%), Positives = 62/117 (52%), Gaps = 2/117 (1%) Query: 3 KILLVDDDRELTSLLKELLEMEGFNVIVAHDGEQALDLL-DDSIDLLLLDVMMPKKNGID 61 IL+ DDD + ++L + L G++V + + + DL++ DV+MP +N D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 TLKALRQTH-QTPVIMLTARGSELDRVLGLELGADDYLPKPFNDRELVARIRAILRR 117 L +++ PV++++A+ + + + E GA DYLPKPF+ EL+ I L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>SECA#SecA protein signature. Length = 901 Score = 28.3 bits (63), Expect = 0.015 Identities = 11/72 (15%), Positives = 26/72 (36%) Query: 9 VEKQPAAMRRIIGKHLAVPRWQDTCDYYNQMMERERLTVCFHAQLKQRHATMRFEEMNDV 68 + ++ L + W D ++ RER+ +++ + E M Sbjct: 703 IPGLQERLKNDFDLDLPIAEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHF 762 Query: 69 ERERLVCAIDEL 80 E+ ++ +D L Sbjct: 763 EKGVMLQTLDSL 774
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 40.8 bits (95), Expect = 5e-06 Identities = 31/155 (20%), Positives = 64/155 (41%), Gaps = 5/155 (3%) Query: 79 LTPEQRQLLEQMQADMRQQPTQLVEVPWNEQTPEQRQQTLQRQRQAQQLAEQQRLAQQSR 138 + +QAD+ P+ E+ ++ P + +AE + Q+S+ Sbjct: 992 VDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSK--QESK 1049 Query: 139 TTEQSWQQQT-RTSQAAPVQAQPRQSKPASSQQPYQDLLQTPAHTTAQSKPQQAAPVARA 197 T E++ Q T T+Q V + + + A++Q + T ++ ++ A V + Sbjct: 1050 TVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKE 1109 Query: 198 ADAPKPTAEKKDERRWMVQCGSFRGAEQAETVRAQ 232 A T + ++ + Q + EQ+ETV+ Q Sbjct: 1110 EKAKVETEKTQEVPKVTSQVSPKQ--EQSETVQPQ 1142
>PF05272#Virulence-associated E family protein Length = 892 Score = 34.7 bits (79), Expect = 6e-04 Identities = 13/35 (37%), Positives = 18/35 (51%) Query: 32 VVFVGPSGCGKSTLLRMIAGLETITSGDLFIGEKR 66 VV G G GKSTL+ + GL+ + IG + Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGK 633
>PERTACTIN#Pertactin signature. Length = 922 Score = 27.0 bits (59), Expect = 0.048 Identities = 15/50 (30%), Positives = 19/50 (38%), Gaps = 4/50 (8%) Query: 119 GGAPAGGNIGGGQPQGGWGQPQQPQGGNQFSG----GAQSRPQQSAPAAP 164 G APAGG + GG GG + + G + QS AP Sbjct: 261 GDAPAGGAVPGGAVPGGAVPGGFGPLLDGWYGVDVSDSTVDLAQSIVEAP 310
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 32.1 bits (73), Expect = 0.021 Identities = 17/61 (27%), Positives = 32/61 (52%), Gaps = 3/61 (4%) Query: 229 VIVSGEGGVGKTAVIKKIYEA-EKQYTPFYVFKASEFKKDSI-NELFGAHGLDDFSNAHQ 286 ++++GE G GK V + +++ +++ PF + +D I +ELFG H F+ A Sbjct: 163 LMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFG-HEKGAFTGAQT 221 Query: 287 D 287 Sbjct: 222 R 222
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 26.7 bits (59), Expect = 0.020 Identities = 5/33 (15%), Positives = 13/33 (39%), Gaps = 1/33 (3%) Query: 17 ELVEKR-QRFATILSIIMLAVYIGFILLIAFAP 48 EL+E R +++ ++ + +L Sbjct: 47 ELIETPVSRRPRLVAYFIMGFLVIAFILSVLGQ 79
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 29.9 bits (67), Expect = 0.006 Identities = 6/21 (28%), Positives = 11/21 (52%) Query: 179 FGNLDDPNSEISQLLRQKPTY 199 GNL++P ++ L+ P Sbjct: 75 TGNLEEPAVMVNYFLQGDPYQ 95
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 32.6 bits (74), Expect = 3e-04 Identities = 20/84 (23%), Positives = 32/84 (38%), Gaps = 5/84 (5%) Query: 50 HLALLDGEVVGMIGLHLQFHLHHVNWIGEIQELVVMPQARGLNVGSKLLAWAEEEARQAG 109 L L+ +G I + + N I+++ V R VG+ LL A E A++ Sbjct: 68 FLYYLENNCIGRIKIRSNW-----NGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENH 122 Query: 110 AEMTELSTNVKRHDAHRFYLREGY 133 L T A FY + + Sbjct: 123 FCGLMLETQDINISACHFYAKHHF 146
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.013 Identities = 17/70 (24%), Positives = 25/70 (35%), Gaps = 8/70 (11%) Query: 36 CVVLHGHSGSGKSTLLRSLYANYLPDEGQIQIKHGDEWVDLVTAPARKVVEI------RK 89 VVL G G GKSTL+ +L + I G + + + E+ R+ Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIAGIV--AYELSEMTAFRR 655 Query: 90 TTVGWVSQFL 99 V F Sbjct: 656 ADAEAVKAFF 665
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 70.2 bits (172), Expect = 4e-16 Identities = 31/109 (28%), Positives = 50/109 (45%), Gaps = 4/109 (3%) Query: 4 VLIIDDDAMVAELNRRYVAQIPGFQCCGTASTLEKAKEIIFNSDTPIDLILLDIYMQKEN 63 +L+ DDDA + + + +++ G+ S I + DL++ D+ M EN Sbjct: 6 ILVADDDAAIRTVLNQALSRA-GYDVR-ITSNAATLWRWI--AAGDGDLVVTDVVMPDEN 61 Query: 64 GLDLLPVLHNARCKSDVIVISSAADAATIKDSLHYGVVDYLIKPFQASR 112 DLLP + AR V+V+S+ T + G DYL KPF + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTE 110
>PF06580#Sensor histidine kinase Length = 349 Score = 41.0 bits (96), Expect = 7e-06 Identities = 21/99 (21%), Positives = 38/99 (38%), Gaps = 18/99 (18%) Query: 442 LIENALE-ALGP-EPGGEISVTLHYRHGWLHCEVNDDGPGIAPDKIDHIFDKGVSTKGSE 499 L+EN ++ + GG+I + +G + EV + G + Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKN------------TKES 310 Query: 500 RGVGLALVKQQVENLGG---SIAVESEPGIFTQFFVQIP 535 G GL V+++++ L G I + + G V IP Sbjct: 311 TGTGLQNVRERLQMLYGTEAQIKLSEKQGKVN-AMVLIP 348
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 26.8 bits (59), Expect = 0.011 Identities = 9/28 (32%), Positives = 16/28 (57%) Query: 32 LAIIEHTDVDESLKGQGIGKQLVAKVVE 59 A+IE V + + +G+G L+ K +E Sbjct: 89 YALIEDIAVAKDYRKKGVGTALLHKAIE 116
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 29.8 bits (67), Expect = 0.023 Identities = 36/190 (18%), Positives = 66/190 (34%), Gaps = 14/190 (7%) Query: 44 NHAISLFSAYA-SLVYVTPILGGWLADRLLGNRTAVIAGALLMTLGHVVLGIDTNSTFSL 102 H L + YA P+LG +DR G R ++ + + ++ + L Sbjct: 43 AHYGILLALYALMQFACAPVLGAL-SDRF-GRRPVLLVSLAGAAVDYAIMAT-APFLWVL 99 Query: 103 YLALAIIICGYGLFKSNISCLLGELYDEND-HRRDGGFSLLYAAGNIGSIAAPIACGLAA 161 Y+ + G+ + + + D D R F + A G +A P+ GL Sbjct: 100 YIGRIV----AGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMG 155 Query: 162 QWYGWHVGFALAGGGMFIGLLIFLSGHRHFQSTRSMDKKALTSVKF-ALPVWSWLVVMLC 220 + H F A + L FL+G + +++ L L + W M Sbjct: 156 G-FSPHAPFFAAA---ALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTV 211 Query: 221 LAPVFFTLLL 230 +A + + Sbjct: 212 VAALMAVFFI 221
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 36.8 bits (85), Expect = 7e-05 Identities = 16/97 (16%), Positives = 36/97 (37%), Gaps = 7/97 (7%) Query: 391 PLDEKQLAALNTEIDNIVTLPELNNLS-----IIYQIKAVSALVKGKTDESYQAINTGID 445 ++ A+ + + T+ LN +S +Y + A + GK +++++ Sbjct: 6 TDTQEYQLAMESFLKGGGTIAMLNEISSDTLEQLYSL-AFNQYQSGKYEDAHKVFQALCV 64 Query: 446 LEMSWLNYVL-LGKVYEMKGMNREAADAYLTAFNLRP 481 L+ + L LG + G A +Y + Sbjct: 65 LDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDI 101
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 44.6 bits (105), Expect = 5e-08 Identities = 28/188 (14%), Positives = 51/188 (27%), Gaps = 13/188 (6%) Query: 3 REDVLGEALKLLELQGIANTTLEMVAERVDYPLDELRRFWPDKEAILYDALRYLSQQIDV 62 R+ +L AL+L QG+++T+L +A+ + + DK + + I Sbjct: 13 RQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGE 72 Query: 63 WRRQLMLDETQTAEQKLLARYQALSECVKNNRYPGCLFIAACTFYPDPGH----PIHQLA 118 + L + E + F+ + Q Sbjct: 73 LELEYQAKFPGDPLSVLREILIHVLEST--VTEERRRLLMEIIFHKCEFVGEMAVVQQAQ 130 Query: 119 DQQKSAAYDFTHELLTT-------LEVDDPAMVAKQMELVLEGCLSRMLVNRSQADVDTA 171 +YD + L A M + G + L D+ Sbjct: 131 RNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLKKE 190 Query: 172 HRLAEDIL 179 R IL Sbjct: 191 ARDYVAIL 198
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 50.8 bits (121), Expect = 2e-08 Identities = 50/312 (16%), Positives = 105/312 (33%), Gaps = 18/312 (5%) Query: 121 SRQAQQEQERAREIADSLNQLPQQQTDARRQLNEIERRLGTLTGNTPLNQAQNFALQSDS 180 + ++ QERA + N L + +D ++ LT L+ + Sbjct: 49 TDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTE---ELSNAKEKLRKND 105 Query: 181 ARLKALVDEL-ELAQLSANNRQELARLRSELAEKES--QQLDAYLQALRNQLNSQRQLEA 237 L ++ EL A+ + L + + + L+A AL + + + Sbjct: 106 KSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAAR-KADLEKAL 164 Query: 238 ERALESTELLAENSADLPKDIVAQFKINRELSAALNQQAQRMDLVASQQRQAASQTLQVR 297 E A+ + + L + A EL AL +++ + ++ + Sbjct: 165 EGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALA 224 Query: 298 QALNTLREQSQWLGSSNLLGEALRAQVARLPEMPKPQQLDTEMAQLRVQRLRYEDLLNKQ 357 L + L + A A++ L + L+ A+L + Sbjct: 225 ARKADLEKA---LEGAMNFSTADSAKIKTLEA--EKAALEARQAELEKALEGAMNFSTAD 279 Query: 358 PLLRQIHQADGQPLTAE------QNRILEAQLRTQRELLNSLLQGGDTLLLELTKLKVSN 411 + +A+ L AE Q+++L A ++ R L++ + L E KL+ N Sbjct: 280 SAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQN 339 Query: 412 GQLEDALKEVNE 423 E + + + Sbjct: 340 KISEASRQSLRR 351 Score = 42.7 bits (100), Expect = 7e-06 Identities = 48/239 (20%), Positives = 92/239 (38%), Gaps = 23/239 (9%) Query: 20 ATAPDSKQITQELEQAKAAKPAQPEVVEALQSALNALEERKGSLER-IKQYQQVIDNYPK 78 A A + + LE A A ++ L++ ALE R+ LE+ ++ Sbjct: 222 ALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSA 281 Query: 79 LSATLRAQLNNMRDEPRSVSPGMSTDALNQEILQVSSQLLDKSRQAQQEQERAREIADSL 138 TL A+ + E + + Q + LD SR+A+++ E + + Sbjct: 282 KIKTLEAEKAALEAEKADL---EHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQ 338 Query: 139 NQLPQQQTDARRQLNEIERRLGTLTGNTPLNQAQNFALQSDSARLKAL--VDELELAQLS 196 N++ ++A RQ + R L L+++ +L+ + E L Sbjct: 339 NKI----SEASRQ--SLRRDLDASR-------EAKKQLEAEHQKLEEQNKISEASRQSLR 385 Query: 197 AN---NRQELARLRSELAEKESQQLDAYLQALRNQLNSQRQLEAERALESTELLAENSA 252 + +R+ ++ L E S +L A + + S++ E E+A +L AE A Sbjct: 386 RDLDASREAKKQVEKALEEANS-KLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKA 443
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 31.1 bits (70), Expect = 0.010 Identities = 27/147 (18%), Positives = 43/147 (29%), Gaps = 25/147 (17%) Query: 329 VLQQQLETPLPLDDEPQPAPRAIPENRVAAGRNHFAEPAAREPVAPRYTPAPA------- 381 + + P +P P P PE + A P+ P P Sbjct: 53 TMVAPADLEPPQAVQPPPEPVVEPE-PEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKV 111 Query: 382 ---------SGSRPAAPWPNAQPGYQ---KQQGEVYRQLLQTPAPMQKLKAPEPQEPALA 429 SRPA+P+ N P + + + + L +PQ PA A Sbjct: 112 EQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQYPARA 171 Query: 430 ANSQSFGRVLTIVHSDCALLERDGNIS 456 + G+V + DG + Sbjct: 172 QALRIEGQVKVKFD-----VTPDGRVD 193
>SECA#SecA protein signature. Length = 901 Score = 32.2 bits (73), Expect = 0.005 Identities = 26/144 (18%), Positives = 54/144 (37%), Gaps = 6/144 (4%) Query: 282 HVIDAADVRVQENIEAVNTVLEEIDAHEIPTLLVMNKIDMLEDFEPRIDRDEENK-PIRV 340 ++D +DV N + IDA+ P L ++ + + R+ D + PI Sbjct: 665 ELLDVSDVSETINSIREDVFKATIDAYIPPQSL--EEMWDIPGLQERLKNDFDLDLPIAE 722 Query: 341 WLSAQTGAGIPQLFQALTERLSGEVAQHTLRLPPQEGRLRSRFYQLQAIEKEWMEEDGSV 400 WL + L + + + + + + R + LQ ++ W E ++ Sbjct: 723 WLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAM 782 Query: 401 SLQVRMPIVDWRRLCKQEPALIDY 424 +R I R +++P +Y Sbjct: 783 D-YLRQGIH-LRGYAQKDP-KQEY 803
>cloacin#Cloacin signature. Length = 551 Score = 31.6 bits (71), Expect = 0.006 Identities = 25/81 (30%), Positives = 30/81 (37%), Gaps = 10/81 (12%) Query: 17 GSSKPGGNSEGNGNKGGRDQGPPDLDDIFRKLSKKLGGLGGGKGTGSGGGSSSQGP---- 72 S G +SE N GG G G GGG GTG G S+ P Sbjct: 33 ASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTG-GNLSAVAAPVAFG 91 Query: 73 -----RPQLGGRVVTIAAAAI 88 P GG V+I+A A+ Sbjct: 92 FPALSTPGAGGLAVSISAGAL 112
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.6 bits (69), Expect = 0.028 Identities = 12/55 (21%), Positives = 24/55 (43%), Gaps = 1/55 (1%) Query: 165 VVPDDSRLSFDILIPPDQIMGARMGFVVVVELTQRPTRRTKAV-GKIVEVLGDNM 218 +VP+D L L+ I +G ++++ P R + GK+ + D + Sbjct: 359 IVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAI 413
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 34.9 bits (80), Expect = 5e-04 Identities = 30/150 (20%), Positives = 64/150 (42%), Gaps = 5/150 (3%) Query: 29 IMYFVAFIDRVNVGFAKDAMKLDIGLSESAFALGAGIFFAAYALFGIPANLILNKIGAQK 88 I+ F + ++ + + + + D ++ F +++ + +++G ++ Sbjct: 21 ILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKR 80 Query: 89 WLSITTAIWGLLSAMMGFVTGETQFIIL---RFLLGLGEAGFYPGILLLASIYFPNKVRG 145 L I S ++GFV G + F +L RF+ G G A F ++++ + Y P + RG Sbjct: 81 LLLFGIIINCFGS-VIGFV-GHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRG 138 Query: 146 SVVGIFVLGVPLALTLGSPISGALLELHGW 175 G+ V + +G I G + W Sbjct: 139 KAFGLIGSIVAMGEGVGPAIGGMIAHYIHW 168
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 88.2 bits (218), Expect = 4e-23 Identities = 67/250 (26%), Positives = 113/250 (45%), Gaps = 24/250 (9%) Query: 6 GKTVLILGGSRGIGAAIVRHFVTDGANVRFTYAGSKDAAERLAQETGATAVFT-----DS 60 GK I G ++GIG A+ R + GA++ + + E++ A A D Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQGAHI-AAVDYNPEKLEKVVSSLKAEARHAEAFPADV 66 Query: 61 ADRDAVIDVV----RKSGALDILVVNAGIGVFGDALELNADDIDRLFKINIHAPYHASVE 116 D A+ ++ R+ G +DILV AG+ G L+ ++ + F +N ++AS Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 117 AARQMP--EGGRILIIGSVNGDRMPVAGMAAYAASKSALQGMARGLARDFGPRGITINVV 174 ++ M G I+ +GS N +P MAAYA+SK+A + L + I N+V Sbjct: 127 VSKYMMDRRSGSIVTVGS-NPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 175 QPGPIDTDA--------NPANGPMRDMLHGF---MAIKRHGQPEEVAGMVAWLAGPEASF 223 PG +TD N A ++ L F + +K+ +P ++A V +L +A Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGH 245 Query: 224 VTGAMHTIDG 233 +T +DG Sbjct: 246 ITMHNLCVDG 255
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 51.2 bits (122), Expect = 3e-10 Identities = 20/100 (20%), Positives = 38/100 (38%), Gaps = 6/100 (6%) Query: 5 KQSRVPGRPRRFAPEQAVSAAKVLFHQKGFDAVSVAEVTDYLGINPPSLYAAFGSKAGLF 64 ++++ + R + + A LF Q+G + S+ E+ G+ ++Y F K+ LF Sbjct: 3 RKTKQEAQETR---QHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLF 59 Query: 65 SRVLNEYVGTEAIPLADILLDDRPVGECLVEVLKEAARRY 104 S + L P + VL+E Sbjct: 60 SEIWELSESN-IGELELEYQAKFP--GDPLSVLREILIHV 96
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 64.6 bits (157), Expect = 5e-14 Identities = 44/240 (18%), Positives = 91/240 (37%), Gaps = 13/240 (5%) Query: 36 TPQRIVVLELSFADALAAVDVSPIGIADDNDAKRILPEVRAHLKPWQSVGTRAQPSLEAI 95 P RIV LE + L A+ + P G+AD + + + E VG R +P+LE + Sbjct: 34 DPNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSE-PPLPDSVIDVGLRTEPNLELL 92 Query: 96 AALKPDLIIADSSRHAGVYIALQQIAPVLLLKSR--NETYAENLQSAAIIGEMVGKKREM 153 +KP ++ S+ + L +IAP + A +S + +++ + Sbjct: 93 TEMKPSFMVW-SAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNLQSAA 151 Query: 154 QARLEQHKERMAQWASQLPKGTR---VAFGTSREQQFNLHTQETWTGSVLASLGLNVPAA 210 + L Q+++ + + K + + + + +L G +P A Sbjct: 152 ETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYG--IPNA 209 Query: 211 MAGSS----MPSIGLEQLLAVNPAWLLVAHYREESIVKRWQQDPLWQMLTAAQKQQVASV 266 G + ++ +++L A +L + + PLWQ + + + V Sbjct: 210 WQGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNSKDMDALMATPLWQAMPFVRAGRFQRV 269
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 32.9 bits (75), Expect = 0.004 Identities = 19/89 (21%), Positives = 29/89 (32%), Gaps = 9/89 (10%) Query: 546 GSFGTVQYSQIGKAVQSGNVEPEKARTWELGTRYDDGALTAEMGLFLINFNNQYDSNQTN 605 G F + NV EK + L + YD+ AL A + Q D+ Sbjct: 187 GFFVQYGGAYKRHHQVQENVNIEKYQIHRLVSGYDNDALYASV------AVQQQDAKLVE 240 Query: 606 DTVTARGKTRHTGLETQARYDLGTLTPTL 634 + T + Y G +TP + Sbjct: 241 E---NYSHNSQTEVAATLAYRFGNVTPRV 266
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 28.2 bits (63), Expect = 0.037 Identities = 17/69 (24%), Positives = 28/69 (40%), Gaps = 10/69 (14%) Query: 187 FISGTGFAMDYRRLSGHALKGSEIIRLVEESDPVAELALRRYELRLAKSLAHVVNILDP- 245 +G + D+R L A + D A+LAL + R+ K++ + Sbjct: 273 VYGISGISSDFRDLEDAAF---------KNGDKRAQLALNVFAYRVKKTIGSYAAAMGGV 323 Query: 246 DVIVLGGGM 254 DVIV G+ Sbjct: 324 DVIVFTAGI 332
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 52.1 bits (125), Expect = 2e-09 Identities = 74/356 (20%), Positives = 126/356 (35%), Gaps = 35/356 (9%) Query: 33 ILSLALGTFGLGMAEFGIMGVLTELAHNVGISIPAAGH---MISYYALGVVVGAPIIALF 89 + ++AL G+G+ IM VL L ++ S H +++ YAL AP++ Sbjct: 11 LSTVALDAVGIGL----IMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGAL 66 Query: 90 SSRYSLKHILLFLVALCVIGNAMFTLSSSYLMLAIGRLVSGFPHGAFFGVGAIVLSKIIK 149 S R+ + +LL +A + A+ + +L IGR+V+G GA + I Sbjct: 67 SDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIAD--IT 124 Query: 150 PGKVTAAVAGMVSGMTVANLLGIPLGTYLSQEFSWRYTFLLIAVFNIAVMASVYFWVPDI 209 G A G +S ++ P+ L FS F A N + F +P+ Sbjct: 125 DGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPES 184 Query: 210 RDEAKGNLREQ----------FHFLRSPAPWLI--FAATMFGNAGVFAWFSYVKPYMMFI 257 + LR + + A + F + G W + Sbjct: 185 HKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFG------E 238 Query: 258 SGFSETAMTFIMMLVGLGM---VLGNMLSGRISGRYSPLRIAAVTDFIIVLALLMLFFCG 314 F A T + L G+ + M++G ++ R R + ++L F Sbjct: 239 DRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFAT 298 Query: 315 GMKTTSLIFAFICCAGLFALSAPLQILLLQNAKGGELLGAAGGQIAF--NLGSAVG 368 I + G+ LQ +L + E G G +A +L S VG Sbjct: 299 RGWMAFPIMVLLASGGIG--MPALQAMLSRQV-DEERQGQLQGSLAALTSLTSIVG 351
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 40.6 bits (95), Expect = 3e-05 Identities = 27/204 (13%), Positives = 61/204 (29%), Gaps = 18/204 (8%) Query: 487 EARIKTLEAQRAQLQAGQPCPLCGSTSHPAVEAYQALEPGVNQSRLLALENEVKKLGEEG 546 EA ++ Q + Q ++E + E + +E + L Sbjct: 133 EADTLKTQSSLLQARLEQ---TRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLT- 188 Query: 547 ATLRGQLDAITKQLQRDENETQSLRQDEQALTQQWQAVTASLNITLQPLDDIQPWLDAQD 606 + ++ Q Q + E R + + + + LDD L Q Sbjct: 189 SLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQA 248 Query: 607 -------EHERQL-RLLSQRHELQGQIAAHNQQIIQYQQQIEQRQQLLLTTLTGYALTLP 658 E E + +++ + Q+ +I+ +++ + QL L Sbjct: 249 IAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLF------KNEILD 302 Query: 659 QEDEEESWLATRQQEAQSWQQRQN 682 + + + E ++RQ Sbjct: 303 KLRQTTDNIGLLTLELAKNEERQQ 326 Score = 35.6 bits (82), Expect = 0.001 Identities = 35/199 (17%), Positives = 72/199 (36%), Gaps = 13/199 (6%) Query: 671 QQEAQSWQQRQNELTALQNRIQQLTPILETLPQSDELPHCEETVVLENWRQVHEQCLALH 730 + + Q + Q R Q L+ +E + E + +V + Sbjct: 133 EADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIK 192 Query: 731 SQQQTLQQQDVLAAQSLQKAQAQFDTAL--------QASVFDDQQAFLAALMDEQTLTQL 782 Q T Q Q +L K +A+ T L + V + ++L+ +Q + + Sbjct: 193 EQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKH 252 Query: 783 EQLKQNLENQRRQAQTLVTQTAETLAQHQQHRPDDGLALTVTVEQIQQELAQTHQKLREN 842 L+Q EN+ +A + L Q + + + + E+ KLR+ Sbjct: 253 AVLEQ--ENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEIL---DKLRQT 307 Query: 843 TTSQGEIRQQLKQDADNRQ 861 T + G + +L ++ + +Q Sbjct: 308 TDNIGLLTLELAKNEERQQ 326 Score = 33.6 bits (77), Expect = 0.004 Identities = 25/212 (11%), Positives = 65/212 (30%), Gaps = 19/212 (8%) Query: 375 QTSDREHLRQWQQQLTHAEQKLNALAAITLTLTADEV------ATALAQHAEQRPLRQHL 428 + Q L A + ++ ++ +++ Q+ + + + Sbjct: 129 ALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLT 188 Query: 429 VALHGQIVPQQKRLAQLQVAIQNVTQEQTQRNAALNEMRQRYKEKTQQLADVKTICEQEA 488 + Q Q + Q ++ + E+ A +N + + +L D ++ ++A Sbjct: 189 SLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQA 248 Query: 489 --RIKTLEAQRAQLQAGQPCPLCGSTSHPAVEAYQALEPGVNQSRLLALENEVKKLGEEG 546 + LE + ++A + Y++ + L A E Sbjct: 249 IAKHAVLEQENKYVEAVN-----------ELRVYKSQLEQIESEILSAKEEYQLVTQLFK 297 Query: 547 ATLRGQLDAITKQLQRDENETQSLRQDEQALT 578 + +L T + E + +QA Sbjct: 298 NEILDKLRQTTDNIGLLTLELAKNEERQQASV 329
>FRAGILYSIN#Fragilysin metallopeptidase (M10C) enterotoxin signature. Length = 405 Score = 29.7 bits (66), Expect = 0.022 Identities = 13/70 (18%), Positives = 23/70 (32%), Gaps = 4/70 (5%) Query: 149 KQQHLLAAITDYYQQHYADACKLRGDQPLPIIATGHLTTVGASKSDAVRDIYIGTLDAFP 208 K+ ++ I ++Y + + + I T D + + I A Sbjct: 135 KEAQMMNEIAEFYAAPFKKTRAINEKEAFECI-YDSRTRSA--GKD-IVSVKINIDKAKK 190 Query: 209 AQNFPPADYI 218 N P DYI Sbjct: 191 ILNLPECDYI 200
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 94.9 bits (236), Expect = 1e-24 Identities = 33/149 (22%), Positives = 62/149 (41%), Gaps = 9/149 (6%) Query: 4 RILVVEDEAPIREMVCFVLEQNGFQPVEAEDYDSAVNQLNEPWPDLILLDWMLPGGSGIQ 63 ILV +D+A IR ++ L + G+ + + + DL++ D ++P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 64 FIKHLKRESMTRDIPVVMLTARGEEEDRVRGLETGADDYITKPFSPKELVARIKAVMRRI 123 + +K+ D+PV++++A+ ++ E GA DY+ KPF EL+ I + Sbjct: 65 LLPRIKKARP--DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA-- 120 Query: 124 SPMAVEEVIEMQGLSLDPTSHRVMAGEEP 152 E L D + G Sbjct: 121 -----EPKRRPSKLEDDSQDGMPLVGRSA 144
>PF06580#Sensor histidine kinase Length = 349 Score = 34.1 bits (78), Expect = 0.001 Identities = 19/105 (18%), Positives = 33/105 (31%), Gaps = 26/105 (24%) Query: 325 LVYNAVNH----TPEGTHITVRWQRVPHGAEFSVEDNGPGIAPEHIPRLTERFYRVDKAR 380 LV N + H P+G I ++ + VE+ G Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKN---------------- 306 Query: 381 SRQTGGSGLGLAIVKHAVNH---HESRLNIESTVGKGTRFSFVIP 422 +G GL V+ + E+++ + GK +IP Sbjct: 307 --TKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAM-VLIP 348
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.0 bits (91), Expect = 3e-05 Identities = 71/347 (20%), Positives = 135/347 (38%), Gaps = 20/347 (5%) Query: 62 KFLWSPLMDRYTPPFFGRRRGWLLATQILLLVAIAAMGFLEPGTQLRWMAALAVVIAFCS 121 +F +P++ + F RR LL + V A M W+ + ++A + Sbjct: 56 QFACAPVLGALSDRF--GRRPVLLVSLAGAAVDYAIMAT----APFLWVLYIGRIVAGIT 109 Query: 122 ASQDIVFDAWKTDVLPAEERGAGAAISVLGYRLGMLVSGGLALWLADKWLGWQGMYWLMA 181 + V A+ D+ +ER + GM+ L + ++ A Sbjct: 110 GATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG--FSPHAPFFAAA 167 Query: 182 AL-LIPCIIATLLAPEP--TDTIPVPKTLEQAVVAPLRDFFGRNNAWLILLLIVLYKLGD 238 AL + + L PE + P+ + + + A L+ + ++ +G Sbjct: 168 ALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQ 227 Query: 239 AFAMSLTTTFLIRGVGFDAGEVGVVNKTLGLLATIVGALYGGILMQRLSLFRALLIFGIL 298 A +L F +DA +G+ G+L ++ A+ G + RL RAL+ G++ Sbjct: 228 VPA-ALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALM-LGMI 285 Query: 299 QGASNAGYWLLSITDKHLYSMGAAVFFENLCGGMGTSAFVALLMTLCNKSFSATQFALLS 358 A GY LL+ + + V GG+G A A+L ++ L+ Sbjct: 286 --ADGTGYILLAFATRGWMAFPIMVLL--ASGGIGMPALQAMLSRQVDEERQGQLQGSLA 341 Query: 359 ALSAVGRVYVGPVAGWFVEAHGWSTF--YLFSVAAAVPGLILLLVCR 403 AL+++ + VGP+ + A +T+ + + AA+ L L + R Sbjct: 342 ALTSLTSI-VGPLLFTAIYAASITTWNGWAWIAGAALYLLCLPALRR 387
>PF06291#Lambda prophage Bor protein Length = 102 Score = 26.5 bits (58), Expect = 0.027 Identities = 11/34 (32%), Positives = 18/34 (52%) Query: 3 KKILFPLVALFMLAGCAKPPTTIEVSPTITLPQQ 36 KK+LF ++ GCA+ T+ PT P++ Sbjct: 7 KKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKE 40
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.043 Identities = 16/73 (21%), Positives = 29/73 (39%), Gaps = 13/73 (17%) Query: 60 ERSALPTPHEIRNHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIG 119 E P+ E + ++G+ A + +Y RL D +++ G Sbjct: 121 EPKRRPSKLEDDSQDGMPLVGRSAAMQ----EIYRVLARLMQTD---------LTLMITG 167 Query: 120 PTGSGKTLLAETL 132 +G+GK L+A L Sbjct: 168 ESGTGKELVARAL 180
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 34.3 bits (78), Expect = 0.002 Identities = 34/133 (25%), Positives = 68/133 (51%), Gaps = 15/133 (11%) Query: 191 ERLEYLMAMMESEIDLLQVEKRIRNRVKKQMEKSQREYYLNEQMKAIQKELGEMDDAPD- 249 LE A +E + +L R +++ ++ S+ +Q++A ++L E + + Sbjct: 291 AALEAEKADLEHQSQVLNAN---RQSLRRDLDASREAK---KQLEAEHQKLEEQNKISEA 344 Query: 250 ENEALKRKIDAAKMPKEAKEKAEAELQKLKMMSPMS-AEATVVRGYIDWMVQVPWNARSK 308 ++L+R +DA++ EAK++ EAE QKL+ + +S A +R +D + A+ + Sbjct: 345 SRQSLRRDLDASR---EAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASRE----AKKQ 397 Query: 309 VKKDLRQAQEILD 321 V+K L +A L Sbjct: 398 VEKALEEANSKLA 410
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 117 bits (294), Expect = 3e-38 Identities = 49/88 (55%), Positives = 67/88 (76%) Query: 2 NKSQLIDKIAAGADISKAAAGRALDAIIASVTESLKEGDDVALVGFGTFAVKERAARTGR 61 NK LI K+A +++K + A+DA+ ++V+ L +G+ V L+GFG F V+ERAAR GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 62 NPQTGKEITIAAAKVPSFRAGKALKDAV 89 NPQTG+EI I A+KVP+F+AGKALKDAV Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAV 90
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 60.6 bits (147), Expect = 4e-13 Identities = 26/122 (21%), Positives = 55/122 (45%), Gaps = 2/122 (1%) Query: 1 MKPTSVIIMDTHPIIRMSIEVLLQKNSELQIVLKTDDYRITIDYLRTRPVDLIIMDIDLP 60 M ++++ D IR + L + V T + ++ DL++ D+ +P Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGY--DVRITSNAATLWRWIAAGDGDLVVTDVVMP 58 Query: 61 GTDGFTFLKRIKQIQSTVKVLFLSSKSECFYAGRAIQAGANGFVSKCNDQNDIFHAVQMI 120 + F L RIK+ + + VL +S+++ A +A + GA ++ K D ++ + Sbjct: 59 DENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 121 LS 122 L+ Sbjct: 119 LA 120
>PF06580#Sensor histidine kinase Length = 349 Score = 31.4 bits (71), Expect = 0.007 Identities = 28/190 (14%), Positives = 66/190 (34%), Gaps = 46/190 (24%) Query: 306 EELTRMAKMVSDML-FLAQADNNQLIPEKKMLNLADEVGKVFDFFEALAEDRGVELRFVG 364 + M +S+++ + + N + + LADE+ V + + ++F Sbjct: 191 TKAREMLTSLSELMRYSLRYSNARQVS------LADELTVVDSYLQLA------SIQF-E 237 Query: 365 DKCQV-------AGDPLMLRRALSNLLSNALRY----TPTGETIVVRCQTVDHLVQVIVE 413 D+ Q D + + L+ N +++ P G I+++ + V + VE Sbjct: 238 DRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVE 297 Query: 414 NPGTPIAPEHLPRLFDRFYRVDPSRQRKGEGSGIGLAIVK---SIVVAHKGTVAVTSDAR 470 N G+ E +G GL V+ ++ + + ++ Sbjct: 298 NTGSLALKN------------------TKESTGTGLQNVRERLQMLYGTEAQIKLSEKQG 339 Query: 471 GTRFVITLPA 480 ++ +P Sbjct: 340 KVNAMVLIPG 349
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 85.7 bits (212), Expect = 2e-21 Identities = 35/117 (29%), Positives = 62/117 (52%) Query: 2 KLLIVEDEKKTGEYLTKGLTEAGFVVDLADNGLNGYHLAMTGDYDLIILDIMLPDVNGWD 61 +L+ +D+ L + L+ AG+ V + N + GD DL++ D+++PD N +D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 IVRMLRSANKGMPILLLTALGTIEHRVKGLELGADDYLVKPFAFAELLARVRTLLRR 118 ++ ++ A +P+L+++A T +K E GA DYL KPF EL+ + L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 38.7 bits (90), Expect = 4e-05 Identities = 25/189 (13%), Positives = 60/189 (31%), Gaps = 13/189 (6%) Query: 254 QAQTVNSDSLQSVKLPA-GLSSQILLQRPDIMEAEHALM-----AANANIGAARAAFFPS 307 + +S + +K + +I+++ + + L+ A A+ ++ Sbjct: 87 NGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQS----- 141 Query: 308 ISLTSGISTASSDLSSLFNASSGMWNFIPKIEIPIFNAGRNQANLDIAEIRQQQSVVNYE 367 SL + + + + P F + L + + ++Q Sbjct: 142 -SLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQN 200 Query: 368 QKIQNAFKEVADALALRQSLNDQISAQQRYLASLQITLQRARALYQHGAVSYLEVLDAER 427 QK Q + A R ++ +I+ + + L +L A++ VL+ E Sbjct: 201 QKYQ-KELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQEN 259 Query: 428 SLFATRQTL 436 L Sbjct: 260 KYVEAVNEL 268
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 25.9 bits (57), Expect = 0.033 Identities = 9/56 (16%), Positives = 24/56 (42%), Gaps = 1/56 (1%) Query: 3 KALQVAMFSLFTVIGFNAQANEHHHETMSEAQPQVISATGVVKGIDLESKKITIHH 58 + +++ + SL + A+ E + ++ Q+ G++ +DL S + Sbjct: 2 RYIRLCIISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMI-EMDLASGRTLTAW 56
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 695 bits (1794), Expect = 0.0 Identities = 214/1059 (20%), Positives = 440/1059 (41%), Gaps = 54/1059 (5%) Query: 1 MIEWIIRRSVANRFLVLMGALFLSIWGTWTIINTPVDALPDLSDVQVIIKTSYPGQAPQI 60 M + IRR + A+ L + G I+ PV P ++ V + +YPG Q Sbjct: 1 MANFFIRR----PIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQT 56 Query: 61 VENQVTYPLTTTMLSVPGAKTVRGFSQ-FGDSYVYVIFEDGTDPYWARSRVLEYLNQVQG 119 V++ VT + M + + S G + + F+ GTDP A+ +V L Sbjct: 57 VQDTVTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATP 116 Query: 120 KLPAGVSAELGP-DATGVGWIYEYALVDRSGKHDLADLRSLQDWFLKYELKTIPDVAEVA 178 LP V + + + ++ V + D+ +K L + V +V Sbjct: 117 LLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQ 176 Query: 179 SVGGVVKEYQVVIDPQRLAQYGISLAEVKSALDASNQEAGGSSIELA------EAEYMVR 232 G ++ +D L +Y ++ +V + L N + + + + Sbjct: 177 LFGAQ-YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASII 235 Query: 233 ASGYLQTLDDFNHIVLKASENGVPVYLRDVAKVQIGPEMRRGIAELNGEGEVAGGVVILR 292 A + ++F + L+ + +G V L+DVA+V++G E IA +NG+ AG + L Sbjct: 236 AQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGK-PAAGLGIKLA 294 Query: 293 SGKNAREVIAAVKDKLETLKSSLPEGVEIVTTYDRSQLIDRAIDNLSGKLLEEFIVVAVV 352 +G NA + A+K KL L+ P+G++++ YD + + +I + L E ++V +V Sbjct: 295 TGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLV 354 Query: 353 CALFLWHVRSALVAIISLPLGLCIAFIVMHFQGLNANIMSLGGIAIAVGAMVDAAIVMIE 412 LFL ++R+ L+ I++P+ L F ++ G + N +++ G+ +A+G +VD AIV++E Sbjct: 355 MYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVE 414 Query: 413 NAHKRLEEWQHQHPDATLDNKTRWQVITDASVEVGPALFISLLIITLSFIPIFTLEGQEG 472 N + + E D + + ++ AL ++++ FIP+ G G Sbjct: 415 NVERVMME----------DKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTG 464 Query: 473 RLFGPLAFTKTYAMAGAALLAIVVIPILMGYWIRGKIPPESSNPLNRF----------LI 522 ++ + T AMA + L+A+++ P L ++ + E F + Sbjct: 465 AIYRQFSITIVSAMALSVLVALILTPALCATLLKP-VSAEHHENKGGFFGWFNTTFDHSV 523 Query: 523 RVYHPLLLKVLHWPKTTLLVAALSVLTVLWPLNKVGGEFLPQINEGDLLYMPSTLPGISA 582 Y + K+L LL+ AL V ++ ++ FLP+ ++G L M G + Sbjct: 524 NHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQ 583 Query: 583 AEAASMLQKTDKLIM--SVPEVARVFGKTGKAETATDSAPLEMVETTIQLKPQEQW-RPG 639 +L + + V VF G + + + LKP E+ Sbjct: 584 ERTQKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQN---AGMAFVSLKPWEERNGDE 640 Query: 640 MTMDKIIEELDNTVRLPGLANLWVPPIRNRIDMLSTGIKSPIGIKVSGTVLADI-DAMAE 698 + + +I + + + +++ + I +G + A + Sbjct: 641 NSAEAVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQ 700 Query: 699 QIEEVARTVPGVASALAERLEGGRYINVEINREKAARYGMTVADVQLFVTSAVGGAMVGE 758 + A+ + S LE +E+++EKA G++++D+ +++A+GG V + Sbjct: 701 LLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVND 760 Query: 759 TVEGIARYPINLRYPQSWRDSPQALRQLPILTPMKQQITLADVADIKVSTGPSMLKTENA 818 ++ + ++ +R P+ + +L + + + + + G L+ N Sbjct: 761 FIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNG 820 Query: 819 RPTSWIYIDARDRDMVSVVHDLQKAIAEKVQLKPGTSVAFSGQFELLERANHKLKLMVPM 878 P+ I +A L + +A K L G ++G + ++ +V + Sbjct: 821 LPSMEIQGEAAPGTSSGDAMALMENLASK--LPAGIGYDWTGMSYQERLSGNQAPALVAI 878 Query: 879 TLMIIFVLLYLAFRRVGEALLIISSVPFALVGGIWLLWWMGFHLSVATGTGFIALAGVAA 938 + +++F+ L + + ++ VP +VG + V G + G++A Sbjct: 879 SFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSA 938 Query: 939 EFGVVMLMYLRHAIEAVPSLNNPQTFSEQKLDEALYHGAVLRVRPKAMTVAVIIAGLLPI 998 + ++++ + + +E + + EA +R+RP MT I G+LP+ Sbjct: 939 KNAILIVEFAKDLMEK----------EGKGVVEATLMAVRMRLRPILMTSLAFILGVLPL 988 Query: 999 LWGTGAGSEVMSRIAAPMIGGMITAPLLSLFIIPAAYKL 1037 GAGS + + ++GGM++A LL++F +P + + Sbjct: 989 AISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVV 1027
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 47.2 bits (112), Expect = 3e-08 Identities = 36/146 (24%), Positives = 63/146 (43%), Gaps = 5/146 (3%) Query: 197 AREREQGTLDQLLVSPLTTWQIFIGKAVPALIVATFQATIVLAIGIWAYQIPFAGSLALF 256 R Q T + +L + L I +G+ A A IG+ A + + L+L Sbjct: 92 GRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGA---GIGVVAAALGYTQWLSLL 148 Query: 257 YFTMVI--YGLSLVGFGLLISSLCSTQQQAFIGVFVFMMPAILLSGYVSPVENMPVWLQN 314 Y VI GL+ G+++++L + + + P + LSG V PV+ +P+ Q Sbjct: 149 YALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQT 208 Query: 315 LTWINPIRHFTDITKQIYLKDASLDI 340 P+ H D+ + I L +D+ Sbjct: 209 AARFLPLSHSIDLIRPIMLGHPVVDV 234
>PF05272#Virulence-associated E family protein Length = 892 Score = 31.6 bits (71), Expect = 0.012 Identities = 20/90 (22%), Positives = 28/90 (31%), Gaps = 21/90 (23%) Query: 293 TPRFEDAFIDLLGGAGTSESPLGAILHTVEGTPGETVIEAKELTKKFGDFAATDHVNFAV 352 PR E + +LG P + + + K HV + Sbjct: 547 VPRLEKWLVHVLGKTPDDYKP-------------RRLRYLQLVGKYI----LMGHVARVM 589 Query: 353 KRGEIFG----LLGPNGAGKSTTFKMMCGL 378 + G F L G G GKST + GL Sbjct: 590 EPGCKFDYSVVLEGTGGIGKSTLINTLVGL 619 Score = 29.7 bits (66), Expect = 0.046 Identities = 11/23 (47%), Positives = 13/23 (56%) Query: 34 YVTGLVGPDGAGKTTLMRMLAGL 56 Y L G G GK+TL+ L GL Sbjct: 597 YSVVLEGTGGIGKSTLINTLVGL 619
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 62.2 bits (151), Expect = 6e-13 Identities = 42/259 (16%), Positives = 92/259 (35%), Gaps = 25/259 (9%) Query: 82 ALMQAKAGVSVAQAQYDLMLAGYRDEEIAQAAAAVKQAQAAYDYAQNFYNRQQGLWKSRT 141 Q + + +A+ +LA E + + + + L + Sbjct: 201 QKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENK 260 Query: 142 ISA--NDLENARSSRDQAQATLKSAQDKLRQYRSGNREQ---DIAQAKASLEQAQAQLAQ 196 N+L +S +Q ++ + SA+++ + + + + Q ++ +LA+ Sbjct: 261 YVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAK 320 Query: 197 AELNLQDSTLIAPSDGTLLTRAV-EPGTVLNEGGTVFTVSLT-RPVWVRAYVDERNLDQA 254 E Q S + AP + V G V+ T+ + + V A V +++ Sbjct: 321 NEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFI 380 Query: 255 QPGRKVLLYTDGRPDKPYH---GQIGFVSPTAEFTPKTVETPDLRTDLVYRLRIVVT--- 308 G+ ++ + P Y G++ ++ A D R LV+ + I + Sbjct: 381 NVGQNAIIKVEAFPYTRYGYLVGKVKNINLDA--------IEDQRLGLVFNVIISIEENC 432 Query: 309 ----DADDALRQGMPVTVQ 323 + + L GM VT + Sbjct: 433 LSTGNKNIPLSSGMAVTAE 451
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 72.7 bits (178), Expect = 7e-18 Identities = 33/214 (15%), Positives = 77/214 (35%), Gaps = 17/214 (7%) Query: 9 KGEQAKKQLIAAALAQFGEYGMNATT-REIAAQAGQNIAAITYYFGSKEDLYLACAQWIA 67 + ++ ++ ++ AL F + G+++T+ EIA AG AI ++F K DL+ + Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSE 67 Query: 68 DFIGEQFRPHAEEAERLFAQPQPDRAAIRELILRACRNMIKLLTQDDTVNLSKFISREQL 127 IGE E + P + +RE+++ + + + + + F E + Sbjct: 68 SNIGELEL---EYQAKFPGDP---LSVLREILIHVLESTVTEERRRLLMEII-FHKCEFV 120 Query: 128 SPTAAYHLVHEQVISPLHSHLTRLIAAWTGCDANDTRMILHTHALIGEILAFRLGKETIL 187 A + + + + + +A L T + + G Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKH--CIEAKMLPADLMTRRAAIIMRGYISG----- 173 Query: 188 LRTGWTAFDEEKTELINQTVTCHIDLILQGLSQR 221 L W + + + ++ ++L+ Sbjct: 174 LMENWLFAPQSFD--LKKEARDYVAILLEMYLLC 205
>SECA#SecA protein signature. Length = 901 Score = 29.8 bits (67), Expect = 0.025 Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 4/67 (5%) Query: 246 QQVLVFTRTKHGANHLAEQLNKDGIRSAAIHG-NKSQGARTRALADFKSGDIRVLVATDI 304 Q VLV T + + ++ +L K GI+ ++ + A A A + + V +AT++ Sbjct: 450 QPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAA---VTIATNM 506 Query: 305 AARGLDI 311 A RG DI Sbjct: 507 AGRGTDI 513
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 43.2 bits (102), Expect = 8e-07 Identities = 41/201 (20%), Positives = 64/201 (31%), Gaps = 34/201 (16%) Query: 16 AFLFLFAPTAFAAEQTVEAPSVDARAW----------ILMDYASGKVLAEGNADEKLDPA 65 + L A A P + I MD ASG+ L ADE+ Sbjct: 7 CIISLLATLPLAV-HASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMM 65 Query: 66 SLTKIMTSYVVGQALKADKIKLTDMVTVGKDAWATGNPALRGSSVMFLKPGDQVSVADLN 125 S K++ V + A +L + + +P V D ++V +L Sbjct: 66 STFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSP------VSEKHLADGMTVGELC 119 Query: 126 KGVIIQSGNDACIALADYVAGSQESFIGLMNGYAKKLGLTNTT---FQTVHGLDAPGQF- 181 I S N A L V G + + +++G T ++T PG Sbjct: 120 AAAITMSDNSAANLLLATVGGPAG-----LTAFLRQIGDNVTRLDRWETELNEALPGDAR 174 Query: 182 --STARDMA------LLGKAL 194 +T MA L + L Sbjct: 175 DTTTPASMAATLRKLLTSQRL 195
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.8 bits (93), Expect = 1e-05 Identities = 58/269 (21%), Positives = 106/269 (39%), Gaps = 23/269 (8%) Query: 71 LLGPLSDRIGRRPVMLAGVVWFIVTCLAILLAQNIEQFTLLRFLQGISLCFIGAVGYAAI 130 +LG LSDR GRRPV+L + V + A + + R + GI+ GAV A I Sbjct: 62 VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGA-TGAVAGAYI 120 Query: 131 QESFEEAVCIKITALMANVALIAPLLGPLVG---AAWIHVLPWEGMFVLFAALAAISFFG 187 + + + M+ + GP++G + P F AAL ++F Sbjct: 121 ADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAP----FFAAAALNGLNFLT 176 Query: 188 LQRAMPETATRIGEKLSLKELGRDYKLVLKNG-RFVAGALALGFVSLPLLAWIAQSP--I 244 +PE+ L + L G VA +A+ F ++ + Q P + Sbjct: 177 GCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFF----IMQLVGQVPAAL 232 Query: 245 IIITGEQLSSYEYGLLQVPIFGALIAGNL----LLARLTSRRTVRSLIIMGGWPIMIGLL 300 +I GE ++ + + + I +L + + +R R +++G G + Sbjct: 233 WVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYI 292 Query: 301 VAAAATVISSHAYLWMTAGLSIYAFGIGL 329 + A AT ++ + + + GIG+ Sbjct: 293 LLAFAT----RGWMAFPIMVLLASGGIGM 317
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 33.7 bits (77), Expect = 0.001 Identities = 34/150 (22%), Positives = 65/150 (43%), Gaps = 6/150 (4%) Query: 191 LLIGVVVLAMAFAEGSANDWL-PLLMVDGHGFSP-TSGSLIYAGFTLGMTVGRFTGGWFI 248 +IGV+ + F + + P +M D H S GS+I T+ + + + GG + Sbjct: 258 FMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILV 317 Query: 249 DRYSRVAVVR-ASALM--GALGIGLIIFVDSAWVA-GVSVVLWGLGASLGFPLTISAASD 304 DR + V+ + L ++ S ++ + VL GL + TI ++S Sbjct: 318 DRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSL 377 Query: 305 TGPDAPTRVSVVATTGYLAFLVGPPLLGYL 334 +A +S++ T +L+ G ++G L Sbjct: 378 KQQEAGAGMSLLNFTSFLSEGTGIAIVGGL 407
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 50.4 bits (120), Expect = 4e-10 Identities = 14/81 (17%), Positives = 31/81 (38%) Query: 2 RRANDPQRREKIIQATLEAVKLYGIHAVTHRKIATLAGVPLGSMTYYFSGIDELLLEAFS 61 + + R+ I+ L G+ + + +IA AGV G++ ++F +L E + Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 62 SFTEIMSRQYQAFFSDVSDAP 82 + + + P Sbjct: 65 LSESNIGELELEYQAKFPGDP 85
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 32.1 bits (73), Expect = 0.006 Identities = 21/106 (19%), Positives = 34/106 (32%), Gaps = 6/106 (5%) Query: 394 LMIGMITFQFSTFSFGMGNAAGLLFAGIML-GFMRANHPTFG-YIPQ--GALSMVKEFGL 449 L++ + +L+ G ++ G A G YI + FG Sbjct: 76 LLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGF 135 Query: 450 MVFMAGVGLSAGSGINNGLGAIGGQM--LIAGLIVSLVPVVICFLF 493 M G G+ AG + +G A + L + CFL Sbjct: 136 MSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLL 181
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.010 Identities = 9/18 (50%), Positives = 12/18 (66%) Query: 31 LVLLGPSGAGKSSLLRVL 48 +VL G G GKS+L+ L Sbjct: 599 VVLEGTGGIGKSTLINTL 616
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 28.0 bits (62), Expect = 0.041 Identities = 20/54 (37%), Positives = 26/54 (48%), Gaps = 9/54 (16%) Query: 2 RRFFWLVAAALLLAGCAGEKGIVEKEGYQLDTRRQAQAAYPRIKVLVIHYTADD 55 R+ LV ALL AG A I K+G +LD Y ++ L HY +DD Sbjct: 3 RKVLALVIPALLAAGAAHAAEIYNKDGNKLDL-------YGKVDGL--HYFSDD 47
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 75.2 bits (185), Expect = 2e-17 Identities = 70/363 (19%), Positives = 123/363 (33%), Gaps = 65/363 (17%) Query: 1 MKVLVTGATSGLGRNAVEFLCQKGISVRA---------TGRNEAMGKLLEKMGAEFVPAD 51 MK LVTGA +G + + L + G V +A +LL + G +F D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 52 LTELVSSQAKVMLAGIDTLWHCS-------SFTSPWGTQQAFDLANVRATRRLGEWAVAW 104 L + + ++ S +P A+ +N+ + E Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPH----AYADSNLTGFLNILEGCRHN 116 Query: 105 GVRNFIHISSPSLYFDYHHHRDIKEDFRPHRFANEFARSKAASEEVINMLSQANPQTRFT 164 +++ ++ SS S+Y + D + +A +K A+E + + S T Sbjct: 117 KIQHLLYASSSSVYGL-NRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSH-LYGLPAT 174 Query: 165 ILRPQSLFGPHDK--VFIPRLAHMMHHYGSILLPHGGSALVDMTYYENAVHAMWLASQEA 222 LR +++GP + + + + M SI + + G D TY ++ A+ Sbjct: 175 GLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVI 234 Query: 223 CDKLPS--------------GRVYNITNGEHRTLRSIVQKLIDELNIDCRIRSVPYPMLD 268 RVYNI N L +Q L D L I+ + +P D Sbjct: 235 PHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQPGD 294 Query: 269 MIARSMERLGRKSAKEPPLTHYGVSKLNFDFTLDITRAQEELGYQPVITLDEGIEKTAAW 328 + T D E +G+ P T+ +G++ W Sbjct: 295 V----------------LETS-----------ADTKALYEVIGFTPETTVKDGVKNFVNW 327 Query: 329 LRD 331 RD Sbjct: 328 YRD 330
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 55.6 bits (134), Expect = 1e-10 Identities = 29/125 (23%), Positives = 52/125 (41%), Gaps = 17/125 (13%) Query: 4 RILVLGASGYIGQHLVRTLSQQGHQILA---------AARHVDRLAKLQLANVSCHKVDL 54 + LV GA+G+IG H+ + L + GHQ++ + RL L HK+DL Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 55 SWPDNLPALLQD--IDTVYFLVH------SMGEGGDFIAQERQVALNVRDALREVPVKQL 106 + + + L + V+ H S+ + LN+ + R ++ L Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 107 IFLSS 111 ++ SS Sbjct: 122 LYASS 126
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 27.9 bits (62), Expect = 0.025 Identities = 19/90 (21%), Positives = 32/90 (35%), Gaps = 8/90 (8%) Query: 25 LFLLGLTWGCELFAHDGTVNISGSFRRNTCVLAQDSKQINVQLGDVSLTRFSHGNYGPEK 84 F + L C A + F N LA D + L+RF +G P Sbjct: 25 GFFVRLFVACAFAAQAPLSSAELYF--NPRFLADDPQ------AVADLSRFENGQELPPG 76 Query: 85 SFIINLQDCGTDVSTVDVTFSGTPDGVQSE 114 ++ +++ ++T DVTF+ Sbjct: 77 TYRVDIYLNNGYMATRDVTFNTGDSEQGIV 106
>ENTEROVIROMP#Enterobacterial virulence outer membrane protein signature. Length = 171 Score = 139 bits (351), Expect = 3e-44 Identities = 63/200 (31%), Positives = 99/200 (49%), Gaps = 30/200 (15%) Query: 1 MRKVYAAILSAAICLAVSGTPAWASEHQSTLSAGYLHARTNVPGSDNLNGINVKYRYEFT 60 M+K+ AA+ +GT A ST++ GY + + + G N+KYRYE Sbjct: 1 MKKIACLSALAAVLAFTAGTSVAA---TSTVTGGYAQSDAQGQMNK-MGGFNLKYRYEED 56 Query: 61 DT-LGLVTSFSYANAKDEQKTHYSDTRWHEDSVRNRWFSVMAGPSVRVNEWFSAYAMAGM 119 ++ LG++ SF+Y T S T D +N+++ + AGP+ R+N+W S Y + G+ Sbjct: 57 NSPLGVIGSFTY--------TEKSRTASSGDYNKNQYYGITAGPAYRINDWASIYGVVGV 108 Query: 120 AYSRVSTFSGDYLRVTDNKGKTHDVLTGSDDGRHSNTSLAWGAGVQFNPTESVAVDVAYE 179 Y + T T+ HD S+ ++GAG+QFNP E+VA+D +YE Sbjct: 109 GYGKFQT--------TEYPTYKHD---------TSDYGFSYGAGLQFNPMENVALDFSYE 151 Query: 180 GSGSGDWRTDGFIVGVGYKF 199 S +I GVGY+F Sbjct: 152 QSRIRSVDVGTWIAGVGYRF 171
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 45.4 bits (107), Expect = 1e-06 Identities = 54/346 (15%), Positives = 107/346 (30%), Gaps = 43/346 (12%) Query: 9 LKDGTGKPVQNCTIQLKAKRNSTTVVVNTLASENPDE-AGRYSMDVEYGQYSVILLVEGF 67 + D TG+P N A + + +L D A +Y + G+Y + + Sbjct: 928 VADKTGEPNHNELTLFDASKAQRDHLNVSLVGNTVDLGAWKYKLRNVNGRYDL------Y 981 Query: 68 PPSHAGTITVYEDSRPGTLNDFLGAMTEDDARPEALRRFELMV-------------EEVA 114 P + + T N+ + + E + R + E VA Sbjct: 982 NPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVA 1041 Query: 115 RNASAVAQNTAAAKKSASDASTSAREAATRATDAAGSARAASTSAGQAASSAQSASSSAG 174 N+ ++ ++ A++ + RE A A + + A + + ++ ++ Sbjct: 1042 ENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETK 1101 Query: 175 TASTKATEASKSAAAAESSKSAAATSAGAAKTSEMNAAASQKSAATSASTATTKASEAAT 234 +T E ++ + TS + K + Q A + Sbjct: 1102 ETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQ 1161 Query: 235 SARDASASKVAAKSS-------ETSAASSAG-----------SAASSATAAGNSAKAAKT 276 + A + A ++S S + G A + T S+ K Sbjct: 1162 TNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKN 1221 Query: 277 SETNADNSAQAAADSQTASANSATAAKKSE-----TNAKNSEAAAK 317 + S + T S+N + + TNA S+A AK Sbjct: 1222 RHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAK 1267
>LUXSPROTEIN#Bacterial autoinducer-2 (AI-2) production protein LuxS signature. Length = 171 Score = 31.4 bits (71), Expect = 0.002 Identities = 18/66 (27%), Positives = 30/66 (45%), Gaps = 7/66 (10%) Query: 37 TKEHLLPHFL-EHLGNNHLDI------GVGTGFYLTHVPESSLISLMDLNEASLNAASTR 89 T EHL F+ HL + ++I G TGFY++ + S + D A++ Sbjct: 54 TLEHLYAGFMRNHLNGDSVEIIDISPMGCRTGFYMSLIGTPSEQQVADAWIAAMEDVLKV 113 Query: 90 AGESKI 95 ++KI Sbjct: 114 ENQNKI 119
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.017 Identities = 10/36 (27%), Positives = 19/36 (52%), Gaps = 1/36 (2%) Query: 46 LTLLGPSGCGKTTVLRLIAGLE-TVDSGRIMLDNED 80 + L G G GK+T++ + GL+ D+ + +D Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKD 634
>PF06580#Sensor histidine kinase Length = 349 Score = 28.7 bits (64), Expect = 0.048 Identities = 11/69 (15%), Positives = 22/69 (31%), Gaps = 20/69 (28%) Query: 389 NACKYCLE------FVEISARQTDEHLYIVVEDDGPGIPLSKREVIFDRGQRVDTLRPGQ 442 N K+ + + + + + + + VE+ G + +E Sbjct: 266 NGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE--------------ST 311 Query: 443 GVGLAVARE 451 G GL RE Sbjct: 312 GTGLQNVRE 320
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 86.8 bits (215), Expect = 6e-22 Identities = 31/124 (25%), Positives = 62/124 (50%) Query: 2 RVLVVEDNALLRHHLKVQIQDAGHQVDDAEDAKEADYYLNEHIPDIAIVDLGLPDEDGLS 61 +LV +D+A +R L + AG+ V +A ++ D+ + D+ +PDE+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 LIRRWRSNDVSLPILVLTARESWQDKVEVLSAGADDYVTKPFHIEEVMARMQALMRRNSG 121 L+ R + LP+LV++A+ ++ ++ GA DY+ KPF + E++ + + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 LASQ 125 S+ Sbjct: 125 RPSK 128
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 143 bits (361), Expect = 3e-39 Identities = 62/206 (30%), Positives = 102/206 (49%), Gaps = 1/206 (0%) Query: 258 GKAFYYQPVLCTVQAKSTLTVEEEQDRLRQAIDFTLLDLMTLTAKAEASGLDDIAAIFSG 317 KAF + ++ S V E ++L A++ + +L + + EAS D A IF+ Sbjct: 17 AKAFIHLEPNVDIEKTSITDVSTEIEKLTAALEKSKEELRAIKDQTEASMGADKAEIFAA 76 Query: 318 HHTLLDDPELLAAASELLQHEHCTAEYAWQQVLKELSQQYQQLDDEYLQARYIDVDDLLH 377 H +LDDPEL+ +++E AEYA ++V ++ +D+EY++ R D+ D+ Sbjct: 77 HLLVLDDPELVDGIKGKIENEQMNAEYALKEVSDMFVSMFESMDNEYMKERAADIRDVSK 136 Query: 378 RTLVHLT-QTKEELPQFNSPTILLAENIYPSTVLQLDPAVVKGICLSAGSPVSHSALIAR 436 R L HL L T+++AE++ PS QL+ VKG G SHSA+++R Sbjct: 137 RVLGHLIGVETGSLATIAEETVIIAEDLTPSDTAQLNKQFVKGFATDIGGRTSHSAIMSR 196 Query: 437 ELGIGWICQQGEKLYAIQPEETLTLD 462 L I + E IQ + + +D Sbjct: 197 SLEIPAVVGTKEVTEKIQHGDMVIVD 222
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 28.5 bits (63), Expect = 0.019 Identities = 10/47 (21%), Positives = 26/47 (55%) Query: 138 VESLRQSSEQNLSVPVALEAASSIAESAAQSTITMQARKGRASYLGE 184 E++ + ++N + +EA ++A +A + + A+ G+A+ G+ Sbjct: 293 REAVDRWIQENPNAAETVEAVFNVAAAAKVAKLAKAAKPGKAAVSGD 339
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 244 bits (625), Expect = 6e-76 Identities = 91/363 (25%), Positives = 155/363 (42%), Gaps = 33/363 (9%) Query: 308 QMRQLMTSQLGKVSHTFAHMPQDDPQTRRLIHFGRQAARSSFPVLLCGEEGVGKALLSQA 367 + S+L S + + + + ++ +++ GE G GK L+++A Sbjct: 120 AEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARA 179 Query: 368 IHNESERAAGPYIAVNCELYGDAALAEEFIG---GDRTDNENGRLSRLELAHGGTLFLEK 424 +H+ +R GP++A+N + E G G T + R E A GGTLFL++ Sbjct: 180 LHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDE 239 Query: 425 IEYLAVELQSALLQVIKQGVITRLDARRLIPIDVKVIATTTADLAMLVEQNRFSRQLYYA 484 I + ++ Q+ LL+V++QG T + R I DV+++A T DL + Q F LYY Sbjct: 240 IGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYR 299 Query: 485 LHAFEITIPPLRMRRGSIPALVNNKLRSLEKRFSTRLKIDDDALARLVSCAWPGNDFELY 544 L+ + +PPLR R IP LV + ++ EK + D +AL + + WPGN EL Sbjct: 300 LNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELE 359 Query: 545 SVIENLALSSDNGRIRVSDLPEHLFTEQATDDVSATRLSTS------------------- 585 +++ L I + L +E + + Sbjct: 360 NLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASF 419 Query: 586 -----------LSFAEVEKEAIINAAQVTGGRIQEMSALLGIGRTTLWRKMKQHGIDAGQ 634 AE+E I+ A T G + + LLG+ R TL +K+++ G+ + Sbjct: 420 GDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVSVYR 479 Query: 635 FKR 637 R Sbjct: 480 SSR 482
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 214 bits (546), Expect = 7e-60 Identities = 242/979 (24%), Positives = 400/979 (40%), Gaps = 115/979 (11%) Query: 14 RLAELKIRSPSIQLIKFGAIGLNAIIFSPLLIAADTGSQYGTNITINDGDRI---TGDTA 70 + A L+ + ++ L GA ++ I Q+G +I +D + +G T Sbjct: 10 KAAPLRRTTLAMALGALGAAPAAHADWNNQSIVKTGERQHGIHIQGSDPGGVRTASGTTI 69 Query: 71 DPSGN-LYGVMTPAGNTPGNINLGNDVTVN---VNDASGYAKGIIIQGKNSSLTANRLTV 126 SG G++ N + N + ++D + K L A+ T+ Sbjct: 70 KVSGRQAQGILLE--NPAAELQFRNGSVTSSGQLSDDGIRRFLGTVTVKAGKLVADHATL 127 Query: 127 DVVGQT---SAIGINLIGDYTHADLGTGSTIKSNDDGIIIGHSSTLTATQFTIENSNGIG 183 VG T I + + G+ A + ST++ G+ I + +T + I + G+ Sbjct: 128 ANVGDTWDDDGIALYVAGEQAQASIAD-STLQGAG-GVQIERGANVTVQRSAIVD-GGLH 184 Query: 184 LTINDYGTSVDLGSGSKITTDGS-TGVYIGGLNGNNANGAARFTATDLTID---VQGYSA 239 + DL + D + T V G + A++LT+D + G A Sbjct: 185 IGALQSLQPEDLPPSRVVLRDTNVTAVPASGAPA----AVSVLGASELTLDGGHITGGRA 240 Query: 240 MGINVQKNSVVDLGTNSTIKTNGDNAHGLWSFGQVSANAL-------TVDVTGAAANGVE 292 G+ + +VV L +TI+ A G G V A+ GV+ Sbjct: 241 AGVAAMQGAVVHL-QRATIRRGDAPAGGAVPGGAVPGGAVPGGFGPGGFGPVLDGWYGVD 299 Query: 293 VRGGTTTIGADSHISSAQGGGLVTSGSDAIINFTGTAAQRNSIFSGGSYGASAQTATAVV 352 V G + + A S + + + G + G A + +G + +G +T A Sbjct: 300 VSGSSVEL-AQSIVEAPELGAAIRVGRGARVTVSGGSLS-------APHGNVIETGGARR 351 Query: 353 NM-QNTDITVD-RNGSLALGLWALSGGRITGDSLAITGAAGARGIYAMTNSQIDLTSDLV 410 Q +++ + G+ A G L L +TG A A+G T + + Sbjct: 352 FAPQAAPLSITLQAGAHAQGKALLYRVLPEPVKLTLTGGADAQGDIVATELPSIPGTSI- 410 Query: 411 IDMSTPDQMAIATQHDDGYATSRINASGRMLINGSVLSKGGLINLDMHPGSVWTGSSLSD 470 P +A+A+ + WTG++ Sbjct: 411 ----GPLDVALAS------------------------------------QARWTGAT--R 428 Query: 471 NVNGGKLDVAMNNSVWNVTSNSNLDTLAL-SHSTVDFASHGSTAGTFATLNVENLSGNST 529 V+ +D N+ W +T NSN+ L L S +VDF + AG F L V L+G+ Sbjct: 429 AVDSLSID----NATWVMTDNSNVGALRLASDGSVDFQQ-PAEAGRFKVLTVNTLAGSGL 483 Query: 530 FIMRADVVGEGNGVNNKGDLLNISGSSAGNHVLAIRNQGSEATTGNEVLTVVKTTDGAAS 589 F M D L + ++G H L +RN GSE + N +L V AA+ Sbjct: 484 FRMNV------FADLGLSDKLVVMQDASGQHRLWVRNSGSEPASANTLLLVQTPLGSAAT 537 Query: 590 FSASS---QVELGGYLYDVRKNG-TNWELYASGTVPEPTPNPEPTPAPAQPPIVNPD-PT 644 F+ ++ +V++G Y Y + NG W L + P P P P+P P P QPP P+ P Sbjct: 538 FTLANKDGKVDIGTYRYRLAANGNGQWSLVGAKAPPAPKPAPQPGPQPPQPPQPQPEAPA 597 Query: 645 PEPAPTPKPTTTADAGGNYLNVGYL--LNYVENRTLMQRMGDLRNQSKDGNIWLRSYG-- 700 P+P + + A+A N VG L Y E+ L +R+G+LR G W R + Sbjct: 598 PQPPAGRELSAAANAAVNTGGVGLASTLWYAESNALSKRLGELRLNPDAGGAWGRGFAQR 657 Query: 701 GSLDSFASGKLSGFDMGYSGIQFGGDKRLSDVM-PLYVGLYIGSTHASPDYSG-GDGTAR 758 LD+ A + FD +G + G D ++ ++G G T ++G G G Sbjct: 658 QQLDNRAGRR---FDQKVAGFELGADHAVAVAGGRWHLGGLAGYTRGDRGFTGDGGGHTD 714 Query: 759 SDYMGMYASYMAQNGFYSDLVIKASRQKNSFHVLDSQNNGVNANGTANGMSISLEAGQRF 818 S ++G YA+Y+A +GFY D ++ASR +N F V S V +G+ SLEAG+RF Sbjct: 715 SVHVGGYATYIADSGFYLDATLRASRLENDFKVAGSDGYAVKGKYRTHGVGASLEAGRRF 774 Query: 819 NLSPTGYGFYIEPQTQLTYSHQNEMTMKASNGLNIHLNHYESLLGRASMILGYDIT-AGN 877 + G+++EPQ +L +A+NGL + S+LGR + +G I AG Sbjct: 775 THAD---GWFLEPQAELAVFRAGGGAYRAANGLRVRDEGGSSVLGRLGLEVGKRIELAGG 831 Query: 878 SQLNVYVKTGAIREFSGDTEYLLNNSREKYSFKGNGWNNGVGVSAQYNKQHTFYLEADYT 937 Q+ Y+K ++EF G N + +G G+G++A + H+ Y +Y+ Sbjct: 832 RQVQPYIKASVLQEFDGAGTVHTNGIAHRTELRGTRAELGLGMAAALGRGHSLYASYEYS 891 Query: 938 QGNLFDQK-QVNGGYRFSF 955 +G + GYR+S+ Sbjct: 892 KGPKLAMPWTFHAGYRYSW 910
>INTIMIN#Intimin signature. Length = 939 Score = 257 bits (658), Expect = 5e-79 Identities = 120/378 (31%), Positives = 197/378 (52%), Gaps = 21/378 (5%) Query: 79 GEQAKAFALGKVRDALSQQVNQHVESWLSPWGNASVDVKVDNEGHFTGSRGSWFVPLQDN 138 G+ AK ALG + Q + +++WL +G A V+++ N F GS + +P D+ Sbjct: 184 GDYAKDTALGIAGN----QASSQLQAWLQHYGTAEVNLQSGNN--FDGSSLDFLLPFYDS 237 Query: 139 DRYLTWSQLGLTQQDNGLVSNVGVGQRWARGNWLVGYNTFYDNLLDENLQRAGFGAEAWG 198 ++ L + Q+G D+ +N+G GQR+ ++GYN F D + R G G E W Sbjct: 238 EKMLAFGQVGARYIDSRFTANLGAGQRFFLPENMLGYNVFIDQDFSGDNTRLGIGGEYWR 297 Query: 199 EYLRLSANFYQPFAAWHE--QTATQEQRMARGYDLTARMRMPFYQHLNTSVSLEQYFGDR 256 +Y + S N Y + WHE ++R A G+D+ +P Y L + EQY+GD Sbjct: 298 DYFKSSVNGYFRMSGWHESYNKKDYDERPANGFDIRFNGYLPSYPALGAKLMYEQYYGDN 357 Query: 257 VDLFNSGTGYHNPVALSLGLNYTPVPLVTVTAQHKQGESGENQNNLGLNLNYRFGVPLKK 316 V LFNS NP A ++G+NYTP+PLVT+ ++ G EN + Y+F P + Sbjct: 358 VALFNSDKLQSNPGAATVGVNYTPIPLVTMGIDYRHGTGNENDLLYSMQFRYQFDKPWSQ 417 Query: 317 QLSAGEVAESQSLRGSRYDNPQRNNLPTLEYRQRKTLTVFLATPPWDLKPGETVPLKLQI 376 Q+ V E ++L GSRYD QRNN LEY+++ L++ + + T ++L + Sbjct: 418 QIEPQYVNELRTLSGSRYDLVQRNNNIILEYKKQDILSLNI-PHDINGTERSTQKIQLIV 476 Query: 377 RSRYGIRQLIWQGDTQILS-----LTPGAQANSAEGWTLIMPDWQNGEGASNHWRLSVVV 431 +S+YG+ +++W D+ + S G+Q SA+ + I+P + +G SN ++++ Sbjct: 477 KSKYGLDRIVWD-DSALRSQGGQIQHSGSQ--SAQDYQAILPAYV--QGGSNVYKVTARA 531 Query: 432 EDNQGQRVSSNEITLTLV 449 D G SSN + LT+ Sbjct: 532 YDRNGN--SSNNVLLTIT 547
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 73.7 bits (181), Expect = 2e-17 Identities = 32/117 (27%), Positives = 56/117 (47%), Gaps = 2/117 (1%) Query: 7 ATILLIDDHPMLRTGVKQLISMAPDITVVGEASNGEQGIELAESLDPDLILLDLNMPGMN 66 ATIL+ DD +RT + Q +S A + SN + D DL++ D+ MP N Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRI--TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 67 GLETLDKLREKSLSGRIVVFSVSNHEEDVVTALKRGADGYLLKDMEPEDLLKALHQA 123 + L ++++ ++V S N + A ++GA YL K + +L+ + +A Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118
>PF06580#Sensor histidine kinase Length = 349 Score = 53.3 bits (128), Expect = 1e-09 Identities = 36/172 (20%), Positives = 73/172 (42%), Gaps = 23/172 (13%) Query: 424 PESSRELLSQIRNELNASWAQLRELLTTFRLQLTEPGLRPALEASCEEYSAKFGFPVKLD 483 P +RE+L+ + + S + +LT +++ + S +F ++ + Sbjct: 190 PTKAREMLTSLSELMRYSLRYSNARQVSLADELT------VVDSYLQLASIQFEDRLQFE 243 Query: 484 YQLPPRL----VPSHQAIHLLQIAREALSNALKH-----SQASEVVVTVAQNDNQVKLTV 534 Q+ P + VP L+Q E N +KH Q ++++ +++ V L V Sbjct: 244 NQINPAIMDVQVPPM----LVQTLVE---NGIKHGIAQLPQGGKILLKGTKDNGTVTLEV 296 Query: 535 QDNGCGVPENAIRSNHYGMIIMRDRAQSLRG-DCRVRRRESGGTEVVVTFIP 585 ++ G +N S G+ +R+R Q L G + +++ E G + IP Sbjct: 297 ENTGSLALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 31.3 bits (71), Expect = 0.010 Identities = 35/166 (21%), Positives = 60/166 (36%), Gaps = 22/166 (13%) Query: 258 IMSLLYLATFGSFIGFSAGFAMLSKTQFPDVQILQYAFFGPFIGALARSA---GGALSDR 314 I+S + L+ + I A A L K + + FFG F S ++ Sbjct: 474 IVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKI 533 Query: 315 LGGTRVTLVNFILMAIFSGLLFLTLPTD----GQGGSFMAFFAVFLALFLTAGLGSGSTF 370 LG T L+ + L+ +LFL LP+ G F+ L +G+T Sbjct: 534 LGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTM----------IQLPAGATQ 583 Query: 371 QMISVIFRKLTMDRVKAEGGSDER-----AMREAATDTAAALGFIS 411 + + ++T +K E + E + A + F+S Sbjct: 584 ERTQKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVS 629
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.5 bits (222), Expect = 4e-24 Identities = 30/105 (28%), Positives = 51/105 (48%), Gaps = 3/105 (2%) Query: 7 KFLVVDDFSTMRRIVRNLLKELGFNNVEEAEDGVDALNKLQAGGYGFVISDWNMPNMDGL 66 LV DD + +R ++ L G++ V + + AG V++D MP+ + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYD-VRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 67 ELLKTIRADGAMSALPVLMVTAEAKKENIIAAAQAGASGYVVKPF 111 +LL I+ LPVL+++A+ I A++ GA Y+ KPF Sbjct: 64 DLLPRIKKARPD--LPVLVMSAQNTFMTAIKASEKGAYDYLPKPF 106
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 65.2 bits (159), Expect = 8e-14 Identities = 35/188 (18%), Positives = 72/188 (38%), Gaps = 23/188 (12%) Query: 1 MSKIRVLSVDDSALMRQIMTEIINSHSDMEMVATAPDPLVARDLIKKFNPDVLTLDVEMP 60 M+ +L DD A +R ++ + ++ V + I + D++ DV MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAG--YDVRITSNAATLWRWIAAGDGDLVVTDVVMP 58 Query: 61 RMDGLDFLEKLMRLRPMPVVMVSSLTGKGS-EVTLRALELGAIDFVTKPQLGIREGMLAY 119 + D L ++ + RP V+V ++ + + ++A E GA D++ KP + E + Sbjct: 59 DENAFDLLPRIKKARPDLPVLV--MSAQNTFMTAIKASEKGAYDYLPKP-FDLTELIGII 115 Query: 120 NEMIAEKVRTAAKASLAAHKPLSAPTTLKAGPLLSSEKLIAIGASTGGTEAIRHVLQPLP 179 +AE R +K + + +G S E R + + + Sbjct: 116 GRALAEPKRRPSKLEDDSQDGMP-----------------LVGRSAAMQEIYRVLARLMQ 158 Query: 180 LSSPALLI 187 ++ Sbjct: 159 TDLTLMIT 166
>PF06580#Sensor histidine kinase Length = 349 Score = 42.5 bits (100), Expect = 3e-06 Identities = 23/151 (15%), Positives = 49/151 (32%), Gaps = 52/151 (34%) Query: 361 ELDKSLIERIIDPLT--HLVRNSLDHGIELPEKRLAAGKNSVGNLILSAEHQGGNICIEV 418 +++ ++++ + P+ LV N + HGI G ++L G + +EV Sbjct: 245 QINPAIMDVQVPPMLVQTLVENGIKHGIA--------QLPQGGKILLKGTKDNGTVTLEV 296 Query: 419 TDDGAGLNRERILAKAASQGLTVSENMSDDEVAMLIFAPGFSTAEQVTDVSGRGVGMDVV 478 + G+ + G G+ V Sbjct: 297 ENTGSLALKNTK--------------------------------------ESTGTGLQNV 318 Query: 479 KRNIQEMGG---HVEIQSKQGTGTTIRILLP 506 + +Q + G +++ KQG +L+P Sbjct: 319 RERLQMLYGTEAQIKLSEKQG-KVNAMVLIP 348
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.010 Identities = 22/93 (23%), Positives = 35/93 (37%), Gaps = 11/93 (11%) Query: 46 LISISSPKELIQIAEYFRTPLATAVTGGDRISNSESPIPGGGDDYTQSQGEVNKQPNIEE 105 L +SSP A P + G + ++ PGGGDD GE +++ Sbjct: 384 LADVSSPTAAAGGAGGGEPPKKRDPSAG---AGTDPGGPGGGDD-----GEDPFGEWLDD 435 Query: 106 LKKRM---EQSRLRKLRGDLDQLIESDPKLRAL 135 R+ + L+ R L + + S P L Sbjct: 436 EVARLRLRGRWLLKPRRAALIEALRSAPALAGC 468
>PF05844#YopD protein Length = 295 Score = 33.1 bits (75), Expect = 0.001 Identities = 12/28 (42%), Positives = 22/28 (78%), Gaps = 2/28 (7%) Query: 76 MDLLALLYRLMAKSRQMGMFSLERDIEN 103 ++LL +L+R+ K+R++G+ L+RD EN Sbjct: 74 VELLLILFRIAQKARELGV--LQRDNEN 99
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 49.0 bits (117), Expect = 2e-08 Identities = 32/129 (24%), Positives = 58/129 (44%), Gaps = 20/129 (15%) Query: 132 AMMLH-IRQQAQAQLPDAITQAVIGRPINFQGLGGDEANTQAQGILERAAKRAGFKDVVF 190 M+ H I+Q + ++ P+ + + + I E +A+ AG ++V Sbjct: 89 KMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQV-------ERRAIRE-SAQGAGAREVFL 140 Query: 191 QYEPVAAGLDYEATLQEEKRVLVVDIGGGTTDCSLLLMGPQWRSRLDREASLLGHSGCRI 250 EP+AA + + E +VVDIGGGTT+ +++ + ++ S RI Sbjct: 141 IEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLN-----------GVVYSSSVRI 189 Query: 251 GGNDLDIAL 259 GG+ D A+ Sbjct: 190 GGDRFDEAI 198
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 49.4 bits (118), Expect = 2e-08 Identities = 47/369 (12%), Positives = 105/369 (28%), Gaps = 87/369 (23%) Query: 44 SYKSRWVIVIVVVIAAIAAFWFWQGRNDSQSAAPG-----ATKQAQQSPAGGRRG---MR 95 S + R V ++ IA G+ + + A G + + ++ Sbjct: 54 SRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVK 113 Query: 96 SG-------PLA---PVQAATAVEQAVPRYLTGLGTIIAANTVTVRSRVDG--QLMALHF 143 G L + A + L ++ ++ +L Sbjct: 114 EGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDE 173 Query: 144 QEGQQVKAGDLLAEI------------DPSQFKVALAQTQGQLA-------KDKATLANA 184 Q V ++L Q ++ L + + + + + Sbjct: 174 PYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233 Query: 185 RRDLARYQQLAKTNLVSRQELDAQQALVSETEGTIKADEASVA----------------- 227 + L + L +++ + Q+ E ++ ++ + Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVT 293 Query: 228 --------------------------SAQLQLDWSRITAPVDGRV-GLKQVDVGNQISSG 260 + + S I APV +V LK G +++ Sbjct: 294 QLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTA 353 Query: 261 DTTGIVVITQTHPIDLVFTLPESDIATIVQAQKAGKPLVVEAWDRTNSKKL-SEGTLLSL 319 +T +V++ + +++ + DI I Q A + VEA+ T L + ++L Sbjct: 354 ETL-MVIVPEDDTLEVTALVQNKDIGFINVGQNA--IIKVEAFPYTRYGYLVGKVKNINL 410 Query: 320 DNQIDATTG 328 D D G Sbjct: 411 DAIEDQRLG 419
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 920 bits (2379), Expect = 0.0 Identities = 300/1036 (28%), Positives = 513/1036 (49%), Gaps = 29/1036 (2%) Query: 13 SRLFIMRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAV 72 + FI RP+ +L + +++AG + LPV+ P + P + V YPGA + V Sbjct: 2 ANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTV 61 Query: 73 TAPLERQFGQMSGLKQMSSQS-SGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSD 131 T +E+ + L MSS S S G+ ITL FQ D+A+ +VQ + AT LLP + Sbjct: 62 TQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE 121 Query: 132 LPNPPVYSKVNPADPPIMTLAVTSTAMPMTQVE--DMVETRVAQKISQISGVGLVTLSGG 189 + + S + +M S TQ + D V + V +S+++GVG V L G Sbjct: 122 VQQQGI-SVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 190 QRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGP------SRAVTLSANDQ 243 Q A+R+ L+A + LT V + N A G L G ++ A + Sbjct: 181 QY-AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 244 MQSAEEYRQLII-AYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANI 302 ++ EE+ ++ + +G+ +RL DVA VE G EN + A N + A + ++ GAN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 303 ISTADSIRQMLPQLTESLPKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFL 362 + TA +I+ L +L P+ +KV D T ++ S+ + L AI LV +++YLFL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 363 RNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRY 422 +N+ AT+IP +AVP+ L+GTFA++ +SIN LT+ + +A G +VDDAIVV+EN+ R Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 423 I-EKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAIL 481 + E P A K +I ++ + L AV IP+ F G G ++R+F+IT+ A+ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 482 ISAVVSLTLTPMMCARML---SQESLRKQNRFSRASEKMFDRIIAAYGRGLAKVLNHPWL 538 +S +V+L LTP +CA +L S E + F FD + Y + K+L Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 539 TLSVALSTLLLSVLLWVFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQ 598 L + + V+L++ +P F P +D G+ +Q P ++ + QV D L+ Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 599 DPA--VQSLTSFVGVDGTNPSLNSARLQINLKPLDERDDR---VQKVIARLQTAVDKVPG 653 + V+S+ + G + + N+ ++LKP +ER+ + VI R + + K+ Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIR- 658 Query: 654 VDLFLQPTQDLTIDTQVSRTQYQFTLQ---ATSLDALSTWVPQLMEKLQQLP-QLSDVSS 709 D F+ P I + T + F L DAL+ QL+ Q P L V Sbjct: 659 -DGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRP 717 Query: 710 DWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTE 769 + + + VD++ A LG+S++D++ + A G ++ + ++ ++ + + Sbjct: 718 NGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAK 777 Query: 770 NTPGLAALDTIRLTSSDGGVVPLSSIAKIEQRFAPLSINHLDQFPVTTISFNVPDNYSLG 829 +D + + S++G +VP S+ + + + P I S G Sbjct: 778 FRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSG 837 Query: 830 DAVQAIMDTEKTLNLPVDITTQFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGILYESFI 889 DA A+M+ + LP I + G + + + L+ + V +++ L LYES+ Sbjct: 838 DA-MALMENLAS-KLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWS 895 Query: 890 HPITILSTLPTAGVGALLALLIAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQ 949 P++++ +P VG LLA + + DV ++G++ IG+ KNAI++++FA ++ Sbjct: 896 IPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKE 955 Query: 950 GMSPREAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQV 1009 G EA A +R RPILMT+LA +LG LPL +S G G+ + +GIG++GG++ + + Sbjct: 956 GKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATL 1015 Query: 1010 LTLFTTPVIYLLFDRL 1025 L +F PV +++ R Sbjct: 1016 LAIFFVPVFFVVIRRC 1031
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 923 bits (2386), Expect = 0.0 Identities = 288/1035 (27%), Positives = 508/1035 (49%), Gaps = 36/1035 (3%) Query: 6 LFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVAT 65 FI RP+ +L++ + + G L LPVA P + P + VSA+ PGA +T+ +V Sbjct: 4 FFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQ 63 Query: 66 PLERSLGRIAGVSEMTSSS-SLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMP 124 +E+++ I + M+S+S S GS I L F D + A VQ + A LLP + Sbjct: 64 VIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQ 123 Query: 125 SRPTYRKANPSDAPIMILTLTSDT--YSQGELYDFASTQLAPTISQIDGVGDVDVGGSSL 182 + S + +M+ SD +Q ++ D+ ++ + T+S+++GVGDV + G+ Sbjct: 124 -QQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQY 182 Query: 183 PAVRVGLNPQALFNQGVSLDDVRTAVSNANVRKPQG------ALEDGTHRWQIQTNDELK 236 A+R+ L+ L ++ DV + N + G AL I K Sbjct: 183 -AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK 241 Query: 237 TAAEYQPLIIHYN-NGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQ 295 E+ + + N +G VRL DVA V ++ N KPA L I+ AN + Sbjct: 242 NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALD 301 Query: 296 TVDSIRAKLPELQETIPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRS 355 T +I+AKL ELQ P + + D +P ++ S+ EV +TL ++ LV LV++LFL++ Sbjct: 302 TAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQN 361 Query: 356 GRATIIPAVSVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHL- 414 RAT+IP ++VPV L+GTFA + G+S+N L++ + +A G +VDDAIVV+EN+ R + Sbjct: 362 MRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 415 EAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGIS 474 E + P +A + ++ ++ +++ L AVF+P+ GG G + R+F++T+ A+ +S Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 475 LLVSLTLTPMMCGWMLKASKPREQKRLRGFG----RMLVALQQGYGKSLKWVLNHTRLVG 530 +LV+L LTP +C +LK + GF Y S+ +L T Sbjct: 482 VLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYL 541 Query: 531 VVLLGTIALNIWLYISIPKTFFPEQDTGVLMGGIQADQSISFQ----AMRGKLQDFMKII 586 ++ +A + L++ +P +F PE+D GV + IQ + + + ++K Sbjct: 542 LIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNE 601 Query: 587 RD-DPAVDNVTGFT-GGSRVNSGMMFITLKPRDERS---ETAQQIIDRLRVKLAKEPGAN 641 + +V V GF+ G N+GM F++LKP +ER+ +A+ +I R +++L K Sbjct: 602 KANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGF 661 Query: 642 LFLMAVQDIRVGGRQSNASYQYTLLSDDLAALREWEPKIRKKLATL-----PELADVNSD 696 + + I G + ++ L D + + R +L + L V + Sbjct: 662 VIPFNMPAIVELGTATGFDFE---LIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPN 718 Query: 697 QQDNGAEMNLVYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRY 756 ++ A+ L D++ LG+ + N ++ A G ++ K+ ++ D ++ Sbjct: 719 GLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKF 778 Query: 757 TQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPTGKSLSD 816 ++K++V + G+ +P S F + + I G S D Sbjct: 779 RMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGD 838 Query: 817 ASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILIIAAIATVYIVLGILYESYVH 876 A A ++ ++L P+ + + G + + + N L+ + V++ L LYES+ Sbjct: 839 AMALMENLASKL--PAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSI 896 Query: 877 PLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRHGN 936 P++++ +P VG LLA LFN + ++G++ IG+ KNAI++V+FA + Sbjct: 897 PVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEG 956 Query: 937 LTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRHPLGITIVGGLVMSQLL 996 EA A +R RPI+MT+LA + G LPL +S G GS ++ +GI ++GG+V + LL Sbjct: 957 KGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLL 1016 Query: 997 TLYTTPVVYLFFDRL 1011 ++ PV ++ R Sbjct: 1017 AIFFVPVFFVVIRRC 1031 Score = 79.5 bits (196), Expect = 4e-17 Identities = 77/446 (17%), Positives = 161/446 (36%), Gaps = 26/446 (5%) Query: 592 VDNVTGFTGGS-RVNSGMMFITLKPRDERSETAQQIIDRLRVKLAKEPGANLFLMAVQDI 650 +DN+ + S S + +T + + Q+ ++L++ P + Q I Sbjct: 72 IDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE----VQQQGI 127 Query: 651 RVGGRQSNASYQYTLLSDDLAALREW-----EPKIRKKLATLPELADVNSDQQDNGAE-- 703 V S+ +SD+ ++ ++ L+ L + DV GA+ Sbjct: 128 SVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQL----FGAQYA 183 Query: 704 MNLVYDRDTMARLGID----VQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQD 759 M + D D + + + + + + T P Q + R+ Sbjct: 184 MRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKNP 243 Query: 760 ISALEKMFVINNEGKAIPLSYFAK--WQPANAPLSVNHQGLSAASTISFNLPTGKSLSDA 817 + +N++G + L A+ N + G AA +L D Sbjct: 244 EEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL-DT 302 Query: 818 SAAIDRAMTQL--GVPSTVRGSFA-GTAQVFQETMNSQVILIIAAIATVYIVLGILYESY 874 + AI + +L P ++ + T Q +++ V + AI V++V+ + ++ Sbjct: 303 AKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNM 362 Query: 875 VHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRH 934 L +P +G L F + + + G++L IG++ +AI++V+ Sbjct: 363 RATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMME 422 Query: 935 GNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRHPLGITIVGGLVMSQ 994 L P+EA ++ ++ + +P+ GG + ITIV + +S Sbjct: 423 DKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSV 482 Query: 995 LLTLYTTPVVYLFFDRLRLRFSRKPK 1020 L+ L TP + + + K Sbjct: 483 LVALILTPALCATLLKPVSAEHHENK 508
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 121 bits (305), Expect = 3e-32 Identities = 98/435 (22%), Positives = 190/435 (43%), Gaps = 25/435 (5%) Query: 20 FMQSLDTTIVNTALPSMAQSLGESPLHMHMVIVSYVLTVAVMLPASGWLADKVGVRNIFF 79 F L+ ++N +LP +A + P + V +++LT ++ G L+D++G++ + Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 80 TAIVLFTLGSLFCALSGTLNELL-LARALQGVGGAMMVPVGRLTVMKIVPREQYMAAMTF 138 I++ GS+ + + LL +AR +QG G A + + V + +P+E A Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 139 VTLPGQVGPLLGPALGGLLVEYASWHWIFLINIPVGIIGAIATLL-LMPNYTMQTRRFDL 197 + +G +GPA+GG++ Y HW +L+ IP+ I + L+ L+ FD+ Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHY--IHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDI 201 Query: 198 SGFLLLAVGMAVLTLALDGSKGTGLSPLTIAGLVAVGVVALVLYLLHARNNNRALFSLKL 257 G +L++VG+ L + L V V++ ++++ H R L Sbjct: 202 KGIILMSVGIVFFMLFTTSYSISFLI---------VSVLSFLIFVKHIRKVTDPFVDPGL 252 Query: 258 FRTRTFSLGLAGSFAGRIGSGMLPFMTPVFLQIGLDFSPFHAG-LMMIPMVLGSMGMKRI 316 + F +G+ M P ++ S G +++ P + + I Sbjct: 253 GKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYI 312 Query: 317 VVQVVNRFGYRRVLVATTLGLSLVTLLFMTTALL----GWYYVLPFVLFLQGMVNSTRFS 372 +V+R G VL +G++ +++ F+T + L W+ + V L G+ S + Sbjct: 313 GGILVDRRGPLYVL---NIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGL--SFTKT 367 Query: 373 SMNTLTLKDLPDNLASSGNSLLSMIMQLSMSIGVTIAGLLLGLFGSQHVSVDSGTTQTVF 432 ++T+ L A +G SLL+ LS G+ I G LL + + Q+ + Sbjct: 368 VISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTY 427 Query: 433 MYT--WLSMALIIAL 445 +Y+ L + II + Sbjct: 428 LYSNLLLLFSGIIVI 442
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 31.3 bits (71), Expect = 0.009 Identities = 27/95 (28%), Positives = 35/95 (36%), Gaps = 20/95 (21%) Query: 164 RQTSWLIVALATLLAALATFLLA------RGLLAPVKRLVDGTHKLAAGDFTTRVTPTSE 217 RQ + L+ A L AL L+A V+ V H LA + P S Sbjct: 75 RQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLAD---AMKCFPGSF 131 Query: 218 DEL-----------GKLAQDFNQLASTLEKNQQMR 241 + L G L N+LA E+ QQMR Sbjct: 132 ERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMR 166
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 75.6 bits (186), Expect = 6e-18 Identities = 28/136 (20%), Positives = 65/136 (47%), Gaps = 1/136 (0%) Query: 11 PRILIVEDEPKLGQLLIDYLRAASYAPTLISHGDQVLPYVRQTPPDLILLDLMLPGTDGL 70 IL+ +D+ + +L L A Y + S+ + ++ DL++ D+++P + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 71 TLCREIR-RFSDIPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTILRRCK 129 L I+ D+P+++++A+ + + E GA DY+ KP+ E++ + L K Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 130 PQRELQQQDAESPLII 145 + + D++ + + Sbjct: 124 RRPSKLEDDSQDGMPL 139
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 40.6 bits (95), Expect = 9e-06 Identities = 32/160 (20%), Positives = 66/160 (41%), Gaps = 5/160 (3%) Query: 221 LYTNRNILLSSIVRIINTLSLFGFAVIMPMMFVDELGFTTSEWLQVWAVFFFTTIFSNVF 280 L N ++ + I ++ GF ++P M D +T+E + +V F S + Sbjct: 252 LGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAE---IGSVIIFPGTMSVII 308 Query: 281 WGVLAEKMGWMKVVRWFGCVGMALSSLAFYYMP-QHFGHNFAMALIPAVALGIFVAAFVP 339 +G + + + + +G+ S++F ++ M +I LG Sbjct: 309 FGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTV 368 Query: 340 MAAVFP-ALEPKHKGAAISVYNLSAGLSNFLAPAIAVVLL 378 ++ + +L+ + GA +S+ N ++ LS AI LL Sbjct: 369 ISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLL 408 Score = 29.1 bits (65), Expect = 0.041 Identities = 26/130 (20%), Positives = 50/130 (38%), Gaps = 9/130 (6%) Query: 255 ELGFTTSEWLQVWAVFFFTTIFSNVFWGVLAEKMGWMKVVRWFGCVGMALSSLAFYYMPQ 314 + + V F T +G L++++G +++ + + S + F Sbjct: 43 DFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGF----- 97 Query: 315 HFGHNFAMALIPA-VALGIFVAAFVPMAAVFPA--LEPKHKGAAISVYNLSAGLSNFLAP 371 GH+F LI A G AAF + V A + +++G A + + + P Sbjct: 98 -VGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 372 AIAVVLLPYF 381 AI ++ Y Sbjct: 157 AIGGMIAHYI 166
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 29.0 bits (65), Expect = 0.050 Identities = 17/65 (26%), Positives = 25/65 (38%), Gaps = 13/65 (20%) Query: 383 VLQESGTAIEQCS-------------LVGGGARSPFWAQLLADILDMPVVTHKGGETGGA 429 ++ A+EQC L GGGA +LL + +PVV + T A Sbjct: 267 IVSAVMVALEQCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAEDPLTCVA 326 Query: 430 LGAAR 434 G + Sbjct: 327 RGGGK 331
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 110 bits (276), Expect = 2e-31 Identities = 72/252 (28%), Positives = 118/252 (46%), Gaps = 17/252 (6%) Query: 12 LNGKVAAITGAASGIGLQCAKTLLDAGAKVVLIDREGDKLHKIVAELGENAY---ALQLD 68 + GK+A ITGAA GIG A+TL GA + +D +KL K+V+ L A A D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 69 LFNNQQVDNMLADIIELAGGLDIFHANAGAYIGGPVAEGDPDVWDRVLNLNINAAFRCVR 128 + ++ +D + A I G +DI AG G + + W+ ++N F R Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 129 AVLPHMIAQRSGDIIFTSSIAGVVPVIWEPIYTASKFAVQAFVHTTRRQVSQYGVRVGAV 188 +V +M+ +RSG I+ S VP Y +SK A F ++++Y +R V Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 189 LPGPVVTALLDD-WPKAKMEEALANGSLMQ------------PIEVAESVLFMVT-RSKN 234 PG T + W E + GSL P ++A++VLF+V+ ++ + Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGH 245 Query: 235 VTVRDLVILPGS 246 +T+ +L + G+ Sbjct: 246 ITMHNLCVDGGA 257
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 41.0 bits (96), Expect = 6e-06 Identities = 32/160 (20%), Positives = 65/160 (40%), Gaps = 5/160 (3%) Query: 221 LYTNRNIFLSSIVRIINTLSLFGFAVIMPMMFVDELGFTTSEWLQVWAAFFFTTIFSNIF 280 L N + + I ++ GF ++P M D +T+E + + F S I Sbjct: 252 LGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAE---IGSVIIFPGTMSVII 308 Query: 281 WGIVAEKMGWMRVIRWFGCLGMAASSLAFYYMPQY-FGHNYWMAMIPAIALGTFVAAFVP 339 +G + + R + +G+ S++F +++M +I LG Sbjct: 309 FGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTV 368 Query: 340 MAAVFP-ALEPKHKGAAISVYNLSAGMSNFLAPAIAVVLL 378 ++ + +L+ + GA +S+ N ++ +S AI LL Sbjct: 369 ISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLL 408
>PF09025#YopR Core Length = 143 Score = 28.4 bits (63), Expect = 0.043 Identities = 28/102 (27%), Positives = 40/102 (39%), Gaps = 6/102 (5%) Query: 374 WPRSEQENSPAATRRLFSFQAGALAGGQIVSQAAKRSADGELLLATRNRLSSVVPLSPDA 433 + ++ PAA RRL + GAL + A L + L + +PL Sbjct: 32 FEQALGGEPPAAGRRLAGLENGALGERLLQRFAQPLQGLEADRLELKAMLRAELPLGRQQ 91 Query: 434 ----WQMLSAPLRQPGIVALREYLRQRPPACIRPLN-QVDNL 470 Q+L A PG L + R+ I PLN +DNL Sbjct: 92 QTFLLQLLGAVEHAPGGEYLAQLARRELQVLI-PLNGMLDNL 132
>INTIMIN#Intimin signature. Length = 939 Score = 27.3 bits (60), Expect = 0.028 Identities = 19/94 (20%), Positives = 31/94 (32%) Query: 36 LNGTEIAITYVYKGDKVLKQSSETKIQFASIGATTKEDAAKTLEPLSAKYKNIAGVEEKL 95 + + AITY K K K S ++ F + KT AK + K Sbjct: 671 VANGQDAITYTVKVMKGDKPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKS 730 Query: 96 TYTDTYAQENVTIDMEKVDFKALQGISGINVSAE 129 + + V + +V+F I N+ Sbjct: 731 LVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIV 764
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 71.4 bits (175), Expect = 1e-16 Identities = 41/177 (23%), Positives = 77/177 (43%), Gaps = 12/177 (6%) Query: 2 IKVLIVDDEPLARENLRVFLQEQSDIEIVGECSNAVEGIGAVHKLRPDVLFLDIQMPRIS 61 +L+ DD+ R L L ++ ++ SNA + D++ D+ MP + Sbjct: 4 ATILVADDDAAIRTVLNQAL-SRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 62 GLEMVGMLDPEHRPYI--VFLTAFD--EYAIKAFEEHAFDYLLKPIDEARLEKTLARLRQ 117 +++ + + RP + + ++A + AIKA E+ A+DYL KP D L + R Sbjct: 62 AFDLLPRIK-KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 118 ERSKQDVSLLPENQQALKFIPCTGHSRIYLLQMKDVAFVSSRMSGVYVT--SHEGKE 172 E ++ L ++Q + + G S + +A + + +T S GKE Sbjct: 121 EPKRRPSKLEDDSQDGMPLV---GRSAAMQEIYRVLARLMQTDLTLMITGESGTGKE 174
>PF06580#Sensor histidine kinase Length = 349 Score = 220 bits (562), Expect = 4e-69 Identities = 63/216 (29%), Positives = 115/216 (53%), Gaps = 3/216 (1%) Query: 343 LGEGIAQLLSAQILAGQYERQKAMLTQSEIKLLHAQVNPHFLFNALNTIKAVIRRDSEQA 402 L G + + + +M ++++ L AQ+NPHF+FNALN I+A+I D +A Sbjct: 134 LYFGWHFFKNYKQAEIDQWKMASMAQEAQLMALKAQINPHFMFNALNNIRALILEDPTKA 193 Query: 403 SQLVQYLSTFFRKNLKR-PSEFVTLADEIEHVNAYLQIEKARFQSRLQVNIAIPQELSQQ 461 +++ LS R +L+ + V+LADE+ V++YLQ+ +F+ RLQ I + Sbjct: 194 REMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDV 253 Query: 462 QLPAFTLQPIVENAIKHGTSQLLDTGRVAISARREGQHLMLEIEDNAGL-YQPVTNASGL 520 Q+P +Q +VEN IKHG +QL G++ + ++ + LE+E+ L + ++G Sbjct: 254 QVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGT 313 Query: 521 GMNLVDKRLRERFGDDYGISVACEPDSYTRITLRLP 556 G+ V +RL+ +G + I ++ + + +P Sbjct: 314 GLQNVRERLQMLYGTEAQIKLSEKQGKVN-AMVLIP 348
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 43.6 bits (103), Expect = 5e-07 Identities = 42/195 (21%), Positives = 76/195 (38%), Gaps = 18/195 (9%) Query: 1 MPKFRVSLFSLALMLAVPFAPQAVAKTAAATTASQPEIASGSAMI-VDLNTNKVIYSNHP 59 M R+ + SL + +P A A + S+ +++ MI +DL + + + + Sbjct: 1 MRYIRLCIISL--LATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRA 58 Query: 60 DLVRPIASISKLMTAMVVLDARLPLDEKLKVDISQTPEMKGVYSRV---RLNSEISRKDM 116 D P+ S K++ VL DE+L+ I + YS V L ++ ++ Sbjct: 59 DERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGEL 118 Query: 117 LLLALMSSENRAAASLAHHYPGGYKAFIKAMNAKAKSLGMNNTRFV--EPTGLS-----V 169 A+ S+N +AA+L GG + A + +G N TR E Sbjct: 119 CAAAITMSDN-SAANLLLATVGG----PAGLTAFLRQIGDNVTRLDRWETELNEALPGDA 173 Query: 170 HNVSTARDLTKLLIA 184 + +T + L Sbjct: 174 RDTTTPASMAATLRK 188
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 28.3 bits (63), Expect = 0.019 Identities = 5/33 (15%), Positives = 16/33 (48%), Gaps = 2/33 (6%) Query: 152 WLHNLDQHLKHW-VWLILVVVL-VVGVRWWLKR 182 L + ++ + W++L ++ + R L++ Sbjct: 215 VLMGMSDAVRTFGPWMLLALLAGFMAFRVMLRQ 247
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 113 bits (284), Expect = 1e-32 Identities = 71/253 (28%), Positives = 116/253 (45%), Gaps = 12/253 (4%) Query: 3 QVAIITASDSGIGKECALLLAQQGFDIGITWHSDEEGAKDTAREVVSHGVRAEIVQLDLG 62 ++A IT + GIG+ A LA QG I ++ E+ K + AE D+ Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKA-EARHAEAFPADVR 67 Query: 63 NLPEGALALEKLIQRLGRIDVLVNNAGAMTKAPFLDMAFDEWRKIFTVDVDGAFLCSQIA 122 + ++ + +G ID+LVN AG + ++ +EW F+V+ G F S+ Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 123 ARQMVKQGQGGRIINITSVHEHTPLPDASAYTAAKHALGGLTKAMALELVRHKILVNAVA 182 ++ M+ + + G I+ + S P +AY ++K A TK + LEL + I N V+ Sbjct: 128 SKYMMDR-RSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 183 PGAIATPM-------NGMDDSDVKPDAEP---SIPLRRFGATHEIASLVVWLCSEGANYT 232 PG+ T M + +K E IPL++ +IA V++L S A + Sbjct: 187 PGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHI 246 Query: 233 TGQSLIVDGGFML 245 T +L VDGG L Sbjct: 247 TMHNLCVDGGATL 259
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 28.2 bits (63), Expect = 0.044 Identities = 31/127 (24%), Positives = 53/127 (41%), Gaps = 5/127 (3%) Query: 122 GAKAMREAVPAHLPVSVKVRLGWDSGEK-KFEIADAVQQAGATELVVHGRTKEQGY-RAE 179 G EA+ ++ + +G + E+ K EI A E+ V GR +G R Sbjct: 190 GGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGF 249 Query: 180 HIDWQAIGD-IRQRLNIPVIANGEIWDWQSAQQCMAISGCDAVMIGRGALNIPNLSRVVK 238 ++ I + +++ L V A + + IS V+ G GAL + NL R++ Sbjct: 250 TLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGAL-LRNLDRLL- 307 Query: 239 YNEPRMP 245 E +P Sbjct: 308 MEETGIP 314
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 529 bits (1365), Expect = 0.0 Identities = 252/383 (65%), Positives = 295/383 (77%), Gaps = 19/383 (4%) Query: 1 MKVKVLSLLVPALLVAGAANAAEIYNKDGNKLDLYGKVDGLHYFSDNDSKDGDKTYMRLG 60 MK KVL+L++PALL AGAA+AAEIYNKDGNKLDLYGKVDGLHYFSD+ SKDGD+TYMR+G Sbjct: 1 MKRKVLALVIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSDDSSKDGDQTYMRVG 60 Query: 61 FKGETQVTDQLTGYGQWEYQIQGNEPESDNS-SWTRVAFAGLKFQDVGSFDYGRNYGVVY 119 FKGETQ+ DQLTGYGQWEY +Q N E + + SWTR+AFAGLKF D GSFDYGRNYGV+Y Sbjct: 61 FKGETQINDQLTGYGQWEYNVQANTTEGEGANSWTRLAFAGLKFGDYGSFDYGRNYGVLY 120 Query: 120 DVTSWTDVLPEFGGDTY-DSDNFMQQRGNGFATYRNTDFFGLVDGLDFAVQYQGKNGSAH 178 DV WTD+LPEFGGD+Y +DN+M R NG ATYRNTDFFGLVDGL+FA+QYQGKN S Sbjct: 121 DVEGWTDMLPEFGGDSYTYADNYMTGRANGVATYRNTDFFGLVDGLNFALQYQGKNESQS 180 Query: 179 GEGMT-----TNGRDDVFEQNGDGVGGSITYNY-EGFGIGAAVSSSKRTWDQNNT-GLIG 231 + + N DD+ NGDG G S TY+ GF GAA ++S RT +Q N G I Sbjct: 181 ADDVNIGTNNRNNGDDIRYDNGDGFGISTTYDIGMGFSAGAAYTTSDRTNEQVNAGGTIA 240 Query: 232 TGDRAETYTGGLKYDANNIYLAAQYTQTYNATRVGSL------GWANKAQNFEAVAQYQF 285 GD+A+ +T GLKYDANNIYLA Y++T N T G G ANK QNFE AQYQF Sbjct: 241 GGDKADAWTAGLKYDANNIYLATMYSETRNMTPYGKTDKGYDGGVANKTQNFEVTAQYQF 300 Query: 286 DFGLRPSLAYLQSKGKNLGR---GYDDEDILKYVDVGATYYFNKNMSTYVDYKINLLD-D 341 DFGLRP++++L SKGK+L DD+D++KY DVGATYYFNKN STYVDYKINLLD D Sbjct: 301 DFGLRPAVSFLMSKGKDLTYNNVNGDDKDLVKYADVGATYYFNKNFSTYVDYKINLLDDD 360 Query: 342 NRFTRDAGINTDDIVALGLVYQF 364 + F +DAGI+TDDIVALG+VYQF Sbjct: 361 DPFYKDAGISTDDIVALGMVYQF 383
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 47.9 bits (114), Expect = 9e-09 Identities = 26/145 (17%), Positives = 60/145 (41%), Gaps = 20/145 (13%) Query: 1 MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMP 60 M +++ADD + + ++L + + + ++ L + D +++TD+ MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRI--TSNAATLWRWIAAGDGDLVVTDVVMP 58 Query: 61 GDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLDIEGIVLKQGA------PT 114 + L+ IK+ P L ++V++ N +A+ ++GA P Sbjct: 59 D---ENAFDLLPRIKKARPDLPVLVMSAQNTFM--TAIKA-------SEKGAYDYLPKPF 106 Query: 115 DLPKALAALQKGKKFTPESVSRLLE 139 DL + + + + S+L + Sbjct: 107 DLTELIGIIGRALAEPKRRPSKLED 131
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 82.2 bits (203), Expect = 3e-18 Identities = 29/106 (27%), Positives = 48/106 (45%) Query: 827 ILVVDDHPINRRLLADQLGSLGYQCKTANDGVDALNVLSKNHIDIVLSDVNMPNMDGYRL 886 ILV DD R +L L GY + ++ ++ D+V++DV MP+ + + L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 887 TQRIRQLGLTLPVIGVTANALAEEKQRCLESGMDSCLSKPVTLDVI 932 RI++ LPV+ ++A + E G L KP L + Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTEL 111
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 563 bits (1452), Expect = 0.0 Identities = 181/484 (37%), Positives = 270/484 (55%), Gaps = 35/484 (7%) Query: 1 MTAINRILIVDDEDNVRRMLSTAFALQGFETHCANNGRTALHLFADIHPDVVLMDIRMPE 60 MT IL+ DD+ +R +L+ A + G++ +N T A D+V+ D+ MP+ Sbjct: 1 MTGA-TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPD 59 Query: 61 MDGIKALKEMRSHETRTPVILMTAYAEVETAVEALRCGAFDYVIKPFDLDELNLIVQRAL 120 + L ++ PV++M+A TA++A GA+DY+ KPFDL EL I+ RAL Sbjct: 60 ENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119 Query: 121 QLQSMKKEIRHLHQALSTSWQWGH-ILTNSPAMMDICKDTAKIALSQASVLISGESGTGK 179 + L Q G ++ S AM +I + A++ + +++I+GESGTGK Sbjct: 120 AEP------KRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGK 173 Query: 180 ELIARAIHYNSRRAKGPFIKVNCAALPESLLESELFGHEKGAFTGAQTLRQGLFERANEG 239 EL+ARA+H +R GPF+ +N AA+P L+ESELFGHEKGAFTGAQT G FE+A G Sbjct: 174 ELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGG 233 Query: 240 TLLLDEIGEMPLVLQAKLLRILQEREFERIGGHQTIKVDIRIIAATNRDLQAMVKEGTFR 299 TL LDEIG+MP+ Q +LLR+LQ+ E+ +GG I+ D+RI+AATN+DL+ + +G FR Sbjct: 234 TLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFR 293 Query: 300 EDLFYRLNVIHLILPPLRDRREDISLLANHFLQKFSSENQRDIIDIDPMAMSLLTAWSWP 359 EDL+YRLNV+ L LPPLRDR EDI L HF+Q+ E + D A+ L+ A WP Sbjct: 294 EDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLD-VKRFDQEALELMKAHPWP 352 Query: 360 GNIRELSNVIERAVVMNSGPIIFSEDLPPQIRQPV---------CNAGEVKTAPVGERN- 409 GN+REL N++ R + +I E + ++R + +G + + E N Sbjct: 353 GNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENM 412 Query: 410 ----------------LKEEIKRVEKRIIMEVLEQQEGNRTRTALMLGISRRALMYKLQE 453 + +E +I+ L GN+ + A +LG++R L K++E Sbjct: 413 RQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRE 472 Query: 454 YGID 457 G+ Sbjct: 473 LGVS 476
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 45.6 bits (108), Expect = 2e-07 Identities = 32/165 (19%), Positives = 70/165 (42%), Gaps = 2/165 (1%) Query: 34 LDTIARNFSLSASSAGFIVTAAQLGYAAGLLFLVPLGDMFERRRLIVSMTLLAACGMLIT 93 L IA +F+ +S ++ TA L ++ G L D +RL++ ++ G +I Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 94 ASSQSLA-MMILGTALTGLFSVVAQILVPLA-ATLASPDKRGKVVGTIMSGLLLGILLAR 151 S ++I+ + G + LV + A + RGK G I S + +G + Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 152 TVAGLLANLGGWRTVFWVASVLMALMALALWRGLPQMKSETHLNY 196 + G++A+ W + + + + + + +++ + H + Sbjct: 157 AIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDI 201
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.010 Identities = 24/99 (24%), Positives = 39/99 (39%), Gaps = 12/99 (12%) Query: 23 PYQEILLTRLCMHMQSKLLENRNKMLKAQGINETLFMALITLESQENHSIQPSELSCALG 82 P QE+ L + + L R A+G + + T + ++L ALG Sbjct: 756 PEQELRLVETGVQGRLWALLTREGAPAAEGAAQKGYSVNTTFVTI-------ADLVQALG 808 Query: 83 -----SSRTNATRIADELEKRGWIERRESDNDRRCLYLQ 116 SS ++ D L + GW RE+ RR Y++ Sbjct: 809 ADPGKSSPMLEGQVRDWLNENGWEYLRETSGQRRRGYMR 847
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 78.3 bits (193), Expect = 6e-18 Identities = 64/412 (15%), Positives = 120/412 (29%), Gaps = 97/412 (23%) Query: 25 LLLTLLFIIIAVAIGIYWFLVLRHFEETDDA----YVAGNQIQIMSQVSGSVTKVWADNT 80 L FI+ + I VL E A +G +I + V ++ Sbjct: 57 PRLVAYFIMGFLVIAFILS-VLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEG 115 Query: 81 DFVKEGDVLVTLDPTDARQAFEKA------------------------------------ 104 + V++GDVL+ L A K Sbjct: 116 ESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPY 175 Query: 105 ----------------KTALASSVRQTHQLMINSKQLQANIEVQKIALAKA-------QS 141 K ++ Q +Q +N + +A + + +S Sbjct: 176 FQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKS 235 Query: 142 DYNRRVPLGNANLIGREELQHARDAVTSAQAQLDVAIQQYNANQAMILGTKLEDQPAVQQ 201 + L + I + + + A +L V Q ++ IL K E Q Q Sbjct: 236 RLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQL 295 Query: 202 AATEVRN------------------AWLALERTRIISPMTGYVSRRAVQ-PGAQISPTTP 242 E+ + + + I +P++ V + V G ++ Sbjct: 296 FKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAET 355 Query: 243 LMAVVPA-TNMWVDANFKETQIANMRIGQPVTITTDIYGDDVKY---TGKVVGLDMGTGS 298 LM +VP + V A + I + +GQ I + + +Y GKV + + Sbjct: 356 LMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAF-PYTRYGYLVGKVKNI-----N 409 Query: 299 AFSLLPAQNATGNWIKVVQRLPVRIELDQKQLEQYPLRIGLSTLVSVNTTNR 350 ++ G V+ + + PL G++ + T R Sbjct: 410 LDAIE--DQRLGLVFNVIISIEENCLST--GNKNIPLSSGMAVTAEIKTGMR 457
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 132 bits (333), Expect = 9e-36 Identities = 97/405 (23%), Positives = 169/405 (41%), Gaps = 23/405 (5%) Query: 17 IALSLATFMQVLDSTIANVAIPTIAGNLGSSLSQGTWVITSFGVANAISIPLTGWLAKRV 76 I L + +F VL+ + NV++P IA + + WV T+F + +I + G L+ ++ Sbjct: 17 IWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQL 76 Query: 77 GEVKLFLWSTIAFAIASWACGVS-SSLNMLIFFRVIQGIVAGPLIPLSQSLLLNNYPPAK 135 G +L L+ I S V S ++LI R IQG A L ++ P Sbjct: 77 GIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKEN 136 Query: 136 RSIALALWSMTVIVAPICGPILGGYISDNYHWGWIFFINVPIGVAVVLMTLQTLRGRETR 195 R A L V + GP +GG I+ HW + + +P+ + + L L +E R Sbjct: 137 RGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKEVR 194 Query: 196 TERRRIDAVGLALLVIGIGSLQIMLDRGKELDWFSSQEIIILTVVAVVAICFLIVWELTD 255 + D G+ L+ +GI + ML F++ I +V+V++ + Sbjct: 195 I-KGHFDIKGIILMSVGI--VFFML--------FTTSYSISFLIVSVLSFLIFVKHIRKV 243 Query: 256 DNPIVDLSLFKSRNFTIGCLCISLAYMLYFGAIVLLPQLLQEVYGYTATWAGLASAPVGI 315 +P VD L K+ F IG LC + + G + ++P ++++V+ + G G Sbjct: 244 TDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGT 303 Query: 316 IPVILS-PIIGRFAHKLDMRRLVTFSFIMYAVCFYWRAYTFEPGMDFGASAWPQFIQGF- 373 + VI+ I G + ++ +V F ++ S + I F Sbjct: 304 MSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFL-----LETTSWFMTIIIVFV 358 Query: 374 --AVACFFMPLTTITLSGLPPERLAAASSLSNFTRTLAGSIGTSI 416 ++ ++TI S L + A SL NFT L+ G +I Sbjct: 359 LGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAI 403
>LUXSPROTEIN#Bacterial autoinducer-2 (AI-2) production protein LuxS signature. Length = 171 Score = 292 bits (750), Expect = e-105 Identities = 131/170 (77%), Positives = 148/170 (87%) Query: 2 PLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPNKEVMPERGIHTLEHLFA 61 PLLDSFTVDHTRM APAVRVAKTM TP GD ITVFDLRF PNK+++ E+GIHTLEHL+A Sbjct: 1 PLLDSFTVDHTRMNAPAVRVAKTMQTPKGDTITVFDLRFTAPNKDILSEKGIHTLEHLYA 60 Query: 62 GFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMEDVLKVQDQNQIP 121 GFMRNHLNG+ VEIIDISPMGCRTGFYMSLIGTP EQ+VADAW AAMEDVLKV++QN+IP Sbjct: 61 GFMRNHLNGDSVEIIDISPMGCRTGFYMSLIGTPSEQQVADAWIAAMEDVLKVENQNKIP 120 Query: 122 ELNVYQCGTYQMHSLQEAQDIARSILERDVRINSNEELALPKEKLQELHI 171 ELN YQCGT MHSL EA+ IA++ILE V +N N+ELALP+ L+EL I Sbjct: 121 ELNEYQCGTAAMHSLDEAKQIAKNILEVGVAVNKNDELALPESMLRELRI 170
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 773 bits (1998), Expect = 0.0 Identities = 317/849 (37%), Positives = 469/849 (55%), Gaps = 48/849 (5%) Query: 31 SGMLCTTANAEEYYFDPIMLETTKSGMQTTDLSRFSKKYAQLPGTYQVDIWLNKKKVSQK 90 + ++ E YF+P L DLSRF PGTY+VDI+LN ++ + Sbjct: 35 AFAAQAPLSSAELYFNPRFLAD--DPQAVADLSRFENGQELPPGTYRVDIYLNNGYMATR 92 Query: 91 KITFTAN-AEQLLQPQFTVEQLRELGIKVDEIPALAEKDDDSVINSLEQIIPGTAAEFDF 149 +TF +EQ + P T QL +G+ + + DD+ + L +I A+ D Sbjct: 93 DVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVP-LTSMIHDATAQLDV 151 Query: 150 NHQQLNLSIPQIALYRDARGYVSPSRWDDGIPTLFTNYSFTGSDNRYRQGNRSQRQYLNM 209 Q+LNL+IPQ + ARGY+ P WD GI NY+F+G+ + R G S YLN+ Sbjct: 152 GQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNSHYAYLNL 211 Query: 210 QNGANFGPWRLRNYSTWTRNDQTSS------WNTISSYLQRDIKALKSQLLLGESATSGS 263 Q+G N G WRLR+ +TW+ N SS W I+++L+RDI L+S+L LG+ T G Sbjct: 212 QSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTLGDGYTQGD 271 Query: 264 IFSSYTFTGVQLASDDNMLPNSQRGFAPTVRGIANSSAIVTIRQNGYVIYQSNVSAGAFE 323 IF F G QLASDDNMLP+SQRGFAP + GIA +A VTI+QNGY IY S V G F Sbjct: 272 IFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPPGPFT 331 Query: 324 INDLYPSSNSGDLEVTIEESDGTQRRFIQPYSSLPMMQRPGHLKYSATAGRYRADANSDS 383 IND+Y + NSGDL+VTI+E+DG+ + F PYSS+P++QR GH +YS TAG YR+ Sbjct: 332 INDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYRSGNAQQE 391 Query: 384 KEPEFAEATAIYGLNNTFTLYGGLLGSEDYYALGIGIGGTLGALGALSMDINRADTQFDN 443 K P F ++T ++GL +T+YGG ++ Y A GIG +GALGALS+D+ +A++ + Sbjct: 392 K-PRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQANSTLPD 450 Query: 444 QHSFHGYQWRTQYIKDIPETNTNIAVSYYRYTNDGYFSFNEA------------------ 485 G R Y K + E+ TNI + YRY+ GYF+F + Sbjct: 451 DSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGVIQ 510 Query: 486 ----NTRNWDYNSRQKSEIQFNISQTIFDGVSLYASGSQQDYWGNNDKNRNISVGVSGQQ 541 T ++ ++ ++Q ++Q + +LY SGS Q YWG ++ + G++ Sbjct: 511 VKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSNVDEQFQAGLNTAF 570 Query: 542 WGVGYSLNYQYSRYTDQN-NDRALSLNLSIPLERWLPRSR--------VSYQMTSQKDRP 592 + ++L+Y ++ Q D+ L+LN++IP WL SY M+ + Sbjct: 571 EDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSMSHDLNGR 630 Query: 593 TQHEMRLDGSLLDDGRLSYSLEQSLDDDNNHNS----SLNASYRSPYGTFSAGYSYGNDS 648 + + G+LL+D LSYS++ + NS +YR YG + GYS+ +D Sbjct: 631 MTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIGYSHSDDI 690 Query: 649 SQYNYGVTGGVVIHPHGVTLSQYLGNAFALIDANGASGVRIQNYPGIATDPFGYAVVPYL 708 Q YGV+GGV+ H +GVTL Q L + L+ A GA +++N G+ TD GYAV+PY Sbjct: 691 KQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTDWRGYAVLPYA 750 Query: 709 TTYQENRLSVDTTQLPDNVDLEQTTQFVVPNRGAMVAARFNANIGYRVLVTVSDRNGKPL 768 T Y+ENR+++DT L DNVDL+ VVP RGA+V A F A +G ++L+T+ N KPL Sbjct: 751 TEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKLLMTL-THNNKPL 809 Query: 769 PFGALASNDDTGQQSIVDEGGILYLSGISSKSQSWTVRWGNQADQQCQFAFSTPDSEPTT 828 PFGA+ +++ + IV + G +YLSG+ + V+WG + + C + P Sbjct: 810 PFGAMVTSESSQSSGIVADNGQVYLSGMPLAGK-VQVKWGEEENAHCVANYQLPPESQQQ 868 Query: 829 SVLQGTAQC 837 + Q +A+C Sbjct: 869 LLTQLSAEC 877
>FIMBRIALPAPF#Escherichia coli: P pili tip fibrillum papF protein signature. Length = 167 Score = 29.7 bits (66), Expect = 0.011 Identities = 42/160 (26%), Positives = 67/160 (41%), Gaps = 21/160 (13%) Query: 208 VKLSIQGNLTAPQSCKINQGDVIKVNFGFINGQKFTTRNAMPDGFTPVDFDITYDCGDTS 267 V+++I+GN+ P C IN G I V+FG IN + V +I+ C S Sbjct: 21 VQINIRGNVYIP-PCTINNGQNIVVDFGNINPEHVDNSRG------EVTKNISISCPYKS 73 Query: 268 KIKNSLQMRIDGTTGVVDQYNLVARRRSSDNVPDVGIRIENLGGGVANIPFQNG------ 321 SL +++ G T V Q N++A N+ GI + G + NG Sbjct: 74 ---GSLWIKVTGNTMGVGQNNVLA-----TNITHFGIALYQGKGMSTPLTLGNGSGNGYR 125 Query: 322 ILPVDPSGHGTVNMRAWPVNLVGGELETGKFQGTATITVI 361 + + T + P G L G F+ TA++++I Sbjct: 126 VTAGLDTARSTFTFTSVPFRNGSGILNGGDFRTTASMSMI 165
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 30.4 bits (68), Expect = 0.029 Identities = 11/72 (15%), Positives = 24/72 (33%), Gaps = 4/72 (5%) Query: 487 AGVNGGSGIALTGSPITLRATTDSGMTTNNPTLQTTPTDDQFTNNGGRVDAVYIVATPGE 546 + V+G + + + I + + ++ T D + G R A + + Sbjct: 330 SEVHGNAEVHASFFDIGGSVSAGFSNSNSS----TVAIDHSLSLAGERTWAETMGLNTAD 385 Query: 547 IAFIKPMIAMRN 558 A + I N Sbjct: 386 TARLNANIRYVN 397
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 27.6 bits (61), Expect = 0.036 Identities = 26/111 (23%), Positives = 44/111 (39%), Gaps = 22/111 (19%) Query: 42 NKILCCGNGTSAANAQHFAASMINRFETERPSLPAIALNTDNVVLTAIA-------NDRL 94 K+L GN + A T + IA + V AI+ D+ Sbjct: 277 TKVL--GNVGKGISQYIIAQRAAQGLSTSAAAAGLIA----SAVTLAISPLSFLSIADKF 330 Query: 95 HD----EVYAKQVRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVA 141 E Y+++ + LG+ GD LLA + A++A++T T++A Sbjct: 331 KRANKIEEYSQRFKKLGYDGDSLLAAFHKETG-----AIDASLTTISTVLA 376
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 72.0 bits (176), Expect = 6e-16 Identities = 32/184 (17%), Positives = 63/184 (34%), Gaps = 38/184 (20%) Query: 90 GLGSGVIINASKGYVLTNNHVINQAQKISIQL------------NDGREFDAKLIGSDDQ 137 + SGV++ K +LTN HV++ L +G ++ + Sbjct: 102 FIASGVVVG--KDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGE 159 Query: 138 SDIALLQIQN-------PSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALG 190 D+A+++ + ++++ + +V G P V+ + Sbjct: 160 GDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKP-------VATMW 212 Query: 191 RSGLNLEGLEN-FIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSN 249 S + L+ +Q D S GNSG + N E+IGI+ G+ Sbjct: 213 ESKGKITYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHWG---------GVPNEFNGA 263 Query: 250 MART 253 + Sbjct: 264 VFIN 267
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 52.7 bits (126), Expect = 8e-10 Identities = 31/160 (19%), Positives = 59/160 (36%), Gaps = 26/160 (16%) Query: 77 RTLGSGVIMDQRGYIITNKHVINDADQIIVALQ------------DGRVFEALLVGSDSL 124 + SGV++ + ++TNKHV++ AL+ +G + Sbjct: 101 TFIASGVVVG-KDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGE 159 Query: 125 TDLAVLKI-------NATGGLPTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATG 177 DLA++K + + ++ + + G P + T + G Sbjct: 160 GDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGD-KPVATMW--ESKG 216 Query: 178 RIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINT 217 +I + +Q D S GNSG + N E++GI+ Sbjct: 217 KI---TYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHW 253
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 28.1 bits (62), Expect = 0.045 Identities = 37/167 (22%), Positives = 61/167 (36%), Gaps = 27/167 (16%) Query: 3 VAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSGED 62 + GAA GIG+A+A L G+ ++ D P V S A + F + Sbjct: 11 AFITGAAQGIGEAVARTL---ASQGAHIAAVDYNP-EKLEKVVSSLKAEARHAEAFPADV 66 Query: 63 ATPA------------LEGADVVLISAGVARK------PGMDRSDLFNVNAGIVKNLVQQ 104 A + D+++ AGV R + F+VN+ V N + Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 105 VAKTCPK----ACIGIITNPVNTT-VAIAAEVLKKAGVYDKNKLFGV 146 V+K + + + +NP ++AA KA K G+ Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGL 173
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 169 bits (430), Expect = 4e-57 Identities = 44/141 (31%), Positives = 71/141 (50%), Gaps = 5/141 (3%) Query: 15 KALLKEEKFSSQGEIVAALQEQGFDNINQSKVSRMLTKFGAVRTRNAKMEMVYCLPAELG 74 + ++ + +Q E+V L++ G+ N+ Q+ VSR + + V+ Y LPA+ Sbjct: 11 REIITANEIETQDELVDILKKDGY-NVTQATVSRDIKELHLVKVPTNNGSYKYSLPADQR 69 Query: 75 VPTTSSPLKNLV---LDIDYNDAVVVIHTSPGAAQLIARLLDSLGKAEGILGTIAGDDTI 131 S ++L+ + ID ++V+ T PG AQ I L+D+L E I+GTI GDDTI Sbjct: 70 FNPLSKLKRSLMDAFVKIDSASHLIVLKTMPGNAQAIGALMDNLDWEE-IMGTICGDDTI 128 Query: 132 FTTPANGFTVKDLYEAILELF 152 K + + ILEL Sbjct: 129 LIICRTHDDTKVVQKKILELL 149
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 53.3 bits (128), Expect = 4e-10 Identities = 28/163 (17%), Positives = 59/163 (36%), Gaps = 16/163 (9%) Query: 6 RKFSRTAITVVLVILAFIAIFNAWVYYTE----SPWTRDARFSADVVAIAPDVSGLITQV 61 SR V I+ F+ I + + S I P + ++ ++ Sbjct: 51 TPVSRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEI 110 Query: 62 NVHDNQLVKKGQILFTIDQPR-------YQKALEEAQADVAYYQVLAQEKRQEAGRRNRL 114 V + + V+KG +L + Q +L +A+ + YQ+L++ E + L Sbjct: 111 IVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRS--IELNKLPEL 168 Query: 115 GVQAMSREEIDQANNVL---QTVLHQLAKAQATRDLAKLDLER 154 + + VL + Q + Q + +L+L++ Sbjct: 169 KLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDK 211 Score = 51.4 bits (123), Expect = 2e-09 Identities = 28/147 (19%), Positives = 54/147 (36%), Gaps = 15/147 (10%) Query: 100 LAQEKRQEAGRRNRLGVQ-AMSREEIDQANNVLQT-VLHQLAKAQAT-------RDLAKL 150 E R + ++ + ++EE + + +L +L + + Sbjct: 264 AVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEE 323 Query: 151 DLERTVIRAPADGWVTNLNVYT-GEFITRGSTAVALVKQNSFY-VLAYMEETKLEGVRPG 208 + +VIRAP V L V+T G +T T + +V ++ V A ++ + + G Sbjct: 324 RQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVG 383 Query: 209 YRAEIT----PLGSNKVLKGTVDSVAA 231 A I P L G V ++ Sbjct: 384 QNAIIKVEAFPYTRYGYLVGKVKNINL 410
>DNABINDNGFIS#DNA-binding protein FIS signature. Length = 98 Score = 157 bits (399), Expect = 3e-54 Identities = 98/98 (100%), Positives = 98/98 (100%) Query: 1 MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQ 60 MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQ Sbjct: 1 MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQ 60 Query: 61 PLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN 98 PLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN Sbjct: 61 PLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN 98
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 41.4 bits (97), Expect = 3e-06 Identities = 38/217 (17%), Positives = 70/217 (32%), Gaps = 38/217 (17%) Query: 13 ATYQANYDSAKGELAKSEAAAAIAHLTVKRYVPLVGTKYISQQEYDQAIADA-RQADAAV 71 K +L + E+ A + Q + I D RQ + Sbjct: 262 VEAVNELRVYKSQLEQIESEILSAKEEYQLV----------TQLFKNEILDKLRQTTDNI 311 Query: 72 IAAKATVESARINLAYTKVTAPISGRIGK-STVTEGALVTNGQTTELATVQQLDPIYVDV 130 + + + AP+S ++ + TEG +VT +T + V + D + V Sbjct: 312 GLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETL-MVIVPEDDTLEVTA 370 Query: 131 TQSSND--FMRLKQSVEQGNLHKENATSNVELVMENGQTYP-LKGTLQ--FSDVTVDEST 185 + D F+ + Q+ +++ Y L G ++ D D+ Sbjct: 371 LVQNKDIGFINVGQNAI------------IKVEAFPYTRYGYLVGKVKNINLDAIEDQRL 418 Query: 186 GSIT--LRAV------FPNPQHTLLPGMFVRARIDEG 214 G + + ++ N L GM V A I G Sbjct: 419 GLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTG 455
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1406 bits (3642), Expect = 0.0 Identities = 1034/1034 (100%), Positives = 1034/1034 (100%) Query: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 Query: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN Sbjct: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 Query: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG 660 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG Sbjct: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG 660 Query: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL Sbjct: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 Query: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM 780 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM Sbjct: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM 780 Query: 781 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM 840 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM Sbjct: 781 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM 840 Query: 841 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV Sbjct: 841 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900 Query: 901 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV 960 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV Sbjct: 901 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV 960 Query: 961 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF 1020 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF Sbjct: 961 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF 1020 Query: 1021 VPVFFVVIRRCFKG 1034 VPVFFVVIRRCFKG Sbjct: 1021 VPVFFVVIRRCFKG 1034
>adhesinb#Adhesin B signature. Length = 310 Score = 27.5 bits (61), Expect = 0.004 Identities = 14/68 (20%), Positives = 26/68 (38%), Gaps = 10/68 (14%) Query: 1 MKR---LIPVALLTALLAGCAHDSPCVPVYDDQGRLVHTNTCMKGTTQDNWETAGAIAGG 57 MK+ L+ + L LA C+ + +V TN+ + T++ IAG Sbjct: 1 MKKCRFLVLLLLAFVGLAACSSQKSSTETGSSKLNVVATNSIIADITKN-------IAGD 53 Query: 58 AAAVAGLT 65 + + Sbjct: 54 KINLHSIV 61
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 84.6 bits (209), Expect = 2e-21 Identities = 53/200 (26%), Positives = 95/200 (47%), Gaps = 15/200 (7%) Query: 59 DFSLAALWRNENHAGVKDANPVAVNQETPKLSIALNGIVLTSNDETSFVLINEGSEQKRY 118 DF+L + +N AG DA N L+++L G++ +D S +I++ +EQ Sbjct: 64 DFTLFGVSPEKNKAGALDA-SQMSNLPPSTLNLSLTGVMAGDDDSRSIAIISKDNEQFSR 122 Query: 119 SLNEALESAPGT--FIRKINKTSVVFETHGHYEKVTLH-------PGLP--DIIKQPDSE 167 +NE + PG I I VV + G YE + L+ G+P + +Q Sbjct: 123 GVNEEV---PGYNAKIVSIRPDRVVLQYQGRYEVLGLYSQEDSGSDGVPGAQVNEQLQQR 179 Query: 168 SQNVLADYIIATPIRDGEQIYGLRLNPRKGLNAFTTSLLQPGDIALRINNLSLTHPDEVS 227 + ++DY+ +PI + ++ G RLNP ++F LQ D+A+ +N L L ++ Sbjct: 180 ASTTMSDYVSFSPIMNDNKLQGYRLNPGPKSDSFYRVGLQDNDMAVALNGLDLRDAEQAK 239 Query: 228 QALSLLLTQQSAQFTIRRNG 247 +A+ + + T+ R+G Sbjct: 240 KAMERMADVHNFTLTVERDG 259
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 719 bits (1856), Expect = 0.0 Identities = 348/630 (55%), Positives = 469/630 (74%), Gaps = 13/630 (2%) Query: 7 ITCCLLAALLMPCAGHAENEQYGANFNNADIRQFVEIVGQHLGKTILIDPSVQGTISVRS 66 +T + AALL A E++ A+F DI++F+ V ++L KT++IDPSV+GTI+VRS Sbjct: 12 LTLLIFAALLF---RPAAAEEFSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRS 68 Query: 67 NDTFSQQEYYQFFLSILDLYGYSVITLDNGFLKVVRSANVKTSPGMIADSSRPGVGDELV 126 D ++++YYQFFLS+LD+YG++VI ++NG LKVVRS + KT+ +A + PG+GDE+V Sbjct: 69 YDMLNEEQYYQFFLSVLDVYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIGDEVV 128 Query: 127 TRIVPLENVPARDLAPLLRQMMDAGSVGNVVHYEPSNVLILTGRASTINKLIEVIKRVDV 186 TR+VPL NV ARDLAPLLRQ+ D VG+VVHYEPSNVL++TGRA+ I +L+ +++RVD Sbjct: 129 TRVVPLTNVAARDLAPLLRQLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDN 188 Query: 187 IGTEKQQIIHLEYASAEDLAEILNQLISESHGKSQMPALLSAKIVADKRTNSLIISGPEK 246 G + L +ASA D+ +++ +L ++ KS +P + A +VAD+RTN++++SG Sbjct: 189 AGDRSVVTVPLSWASAADVVKLVTEL-NKDTSKSALPGSMVANVVADERTNAVLVSGEPN 247 Query: 247 ARQRITSLLKSLDVEESEEGNTRVYYLKYAKATNLVEVLTGVSEKLKDEKGNARKPSSSG 306 +RQRI +++K LD +++ +GNT+V YLKYAKA++LVEVLTG+S ++ EK A+ Sbjct: 248 SRQRIIAMIKQLDRQQATQGNTKVIYLKYAKASDLVEVLTGISSTMQSEKQAAK---PVA 304 Query: 307 AMD-NVAITADEQTNSLVITADQSVQEKLATVIARLDIRRAQVLVEAIIVEVQDGNGLNL 365 A+D N+ I A QTN+L++TA V L VIA+LDIRR QVLVEAII EVQD +GLNL Sbjct: 305 ALDKNIIIKAHGQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNL 364 Query: 366 GVQWANKNVGAQQFTNTGLPIFNAAQGVADYKKNGGITSANPAWDMFSAYNGMAAGFFNG 425 G+QWANKN G QFTN+GLPI A G Y K+G ++S+ S++NG+AAGF+ G Sbjct: 365 GIQWANKNAGMTQFTNSGLPISTAIAGANQYNKDGTVSSSLA--SALSSFNGIAAGFYQG 422 Query: 426 DWGVLLTALASNNKNDILATPSIVTLDNKLASFNVGQDVPVLSGSQTTSGDNVFNTVERK 485 +W +LLTAL+S+ KNDILATPSIVTLDN A+FNVGQ+VPVL+GSQTTSGDN+FNTVERK Sbjct: 423 NWAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVPVLTGSQTTSGDNIFNTVERK 482 Query: 486 TVGTKLKVTPQVNEGDAVLLEIEQEVSSVD---SSSNSTLGPTFNTRTIQNAVLVKTGET 542 TVG KLKV PQ+NEGD+VLLEIEQEVSSV SS++S LG TFNTRT+ NAVLV +GET Sbjct: 483 TVGIKLKVKPQINEGDSVLLEIEQEVSSVADAASSTSSDLGATFNTRTVNNAVLVGSGET 542 Query: 543 VVLGGLLDDFSKEQVSKVPLLGDIPLVGQLFRYTSTERAKRNLMVFIRPTIIRDDDVYRS 602 VV+GGLLD + KVPLLGDIP++G LFR TS + +KRNLM+FIRPT+IRD D YR Sbjct: 543 VVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRNLMLFIRPTVIRDRDEYRQ 602 Query: 603 LSKEKYTRYRQEQQQRIDGKSKALVGSEDL 632 S +YT + Q ++ ++ + ++DL Sbjct: 603 ASSGQYTAFNDAQSKQRGKENNDAMLNQDL 632
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 515 bits (1329), Expect = 0.0 Identities = 195/405 (48%), Positives = 282/405 (69%), Gaps = 8/405 (1%) Query: 2 NYRYRAMTQDGQKLQGIIDANDERQARLRLREEGLFLLDIRPQK-------SSGVKTRRP 54 Y Y+A+ G+K +G +A+ RQAR LRE GL L + + S+G+ RR Sbjct: 3 QYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLRRK 62 Query: 55 -RISHSELTLFTRQLATLSAAALPLEESLAVIGQQSSNKRLGDVLNQVRSAILEGHPLSD 113 R+S S+L L TRQLATL AA++PLEE+L + +QS L ++ VRS ++EGH L+D Sbjct: 63 IRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLAD 122 Query: 114 ALQHFPTLFDSLYRTLVKAGEKSGLLAPVLEKLADYNENRQKIRSKLIQSLIYPCMLTTV 173 A++ FP F+ LY +V AGE SG L VL +LADY E RQ++RS++ Q++IYPC+LT V Sbjct: 123 AMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLTVV 182 Query: 174 AIGVVIILLTAVVPKITEQFVHMKQQLPLSTRILLGLSDTLQRIGPTLLATVFIVAVGFW 233 AI VV ILL+ VVPK+ EQF+HMKQ LPLSTR+L+G+SD ++ GP +L + + F Sbjct: 183 AIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMAFR 242 Query: 234 LWLKRGNNRHRFHAMLLRVALIGPLICAINSARYLRTLSILQSSGVPLLDGMNLSTESLN 293 + L++ R FH LL + LIG + +N+ARY RTLSIL +S VPLL M +S + ++ Sbjct: 243 VMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDVMS 302 Query: 294 NLEIRQRLANAAENVRQGNSIHLSLEQTAIFPPMMLYMVASGEKSGQLGTLMVRAADNQE 353 N R RL+ A + VR+G S+H +LEQTA+FPPMM +M+ASGE+SG+L +++ RAADNQ+ Sbjct: 303 NDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADNQD 362 Query: 354 TLQQNRIALTLSIFEPALIITMALIVLFIVVSVLQPLLQLNSMIN 398 +++ L L +FEP L+++MA +VLFIV+++LQP+LQLN++++ Sbjct: 363 REFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLMS 407
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 250 bits (639), Expect = 3e-89 Identities = 145/145 (100%), Positives = 145/145 (100%) Query: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK 60 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK 60 Query: 61 LDNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDL 120 LDNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDL Sbjct: 61 LDNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDL 120 Query: 121 LSAGPDGEMGTEDDITNWGLSKKKK 145 LSAGPDGEMGTEDDITNWGLSKKKK Sbjct: 121 LSAGPDGEMGTEDDITNWGLSKKKK 145
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 146 bits (369), Expect = 2e-47 Identities = 51/156 (32%), Positives = 78/156 (50%), Gaps = 22/156 (14%) Query: 3 QQRGFTLLEMMLVLALVAITASVVLFTY--GREDVASTRARETAARFTAALELAIDRATL 60 +QRGFTLLEMML+L L+ ++A +VL + R+D A+ +T ARF A L R Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAA----QTLARFEAQLRFVQQRGLQ 57 Query: 61 SGQPVGIHFSDSAWRIMV----PGKTP-------SAWRWVPLQEDAADESQNDWDEELSI 109 +GQ G+ W+ +V G P S +RW+PL+ S + +L++ Sbjct: 58 TGQFFGVSVHPDRWQFLVLEARDGADPAPADDGWSGYRWLPLRAGRVATSGSIAGGKLNL 117 Query: 110 HL---QPFKPDDSNQPQVVILADGQITPFSLLMANA 142 + + P D P V+I G++TPF L + A Sbjct: 118 AFAQGEAWTPGD--NPDVLIFPGGEMTPFRLTLGEA 151
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 30.2 bits (68), Expect = 0.001 Identities = 17/90 (18%), Positives = 41/90 (45%), Gaps = 8/90 (8%) Query: 1 MNKQSGMTLLEVLLAMSIFTAVALTLMSSMQGQ--RNAIERMRNETLALWIADNQLQSQD 58 +KQ G TLLE+++ + I +A ++ ++ G + ++ ++ +AL A + + D Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK-LD 62 Query: 59 SFGEENTSSSGKELING-----EEWNWRSD 83 + T+ + L+ N+ + Sbjct: 63 NHHYPTTNQGLESLVEAPTLPPLAANYNKE 92
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 33.4 bits (76), Expect = 3e-04 Identities = 12/47 (25%), Positives = 25/47 (53%), Gaps = 2/47 (4%) Query: 4 RQQGFTLLEVMAALAIFSMLSVLAFMIFSQASELHQRSQKEIQQFNQ 50 RQ+GFTLLE+M L + + + + + F + + + + + +F Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGMVLLAFPASRD--DSAAQTLARFEA 46
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 153 bits (388), Expect = 5e-48 Identities = 74/167 (44%), Positives = 96/167 (57%), Gaps = 18/167 (10%) Query: 71 PFTPIVTGALFLY-----------------FCFVLTLSVIDFRTQLLPDKLTLPLLWLGL 113 P ++T L + ++ L+ ID LLPD+LTLPLLW GL Sbjct: 111 PLVELLTALLSVAVAMTLAPGWGTLAALLLTWVLVALTFIDLDKMLLPDQLTLPLLWGGL 170 Query: 114 VFNAQYGLIDLHDAVYGAVAGYGVLWCVYWGVWLVCHKEGLGYGDFKLLAAAGAWCGWQT 173 +FN G + L DAV GA+AGY VLW +YW L+ KEG+GYGDFKLLAA GAW GWQ Sbjct: 171 LFNLLGGFVSLGDAVIGAMAGYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQA 230 Query: 174 LPMILLIASLGGIGYAIVSQLLQRRTITT-IAFGPWLALGSMINLGY 219 LP++LL++SL G I LL+ + I FGP+LA+ I L + Sbjct: 231 LPIVLLLSSLVGAFMGIGLILLRNHHQSKPIPFGPYLAIAGWIALLW 277
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 35.2 bits (81), Expect = 3e-05 Identities = 28/150 (18%), Positives = 59/150 (39%), Gaps = 24/150 (16%) Query: 5 TKVINYLNKLLGNE---LVAINQYFLHARMFKNWGLKRLNDVEYHESIDEM-----KHAD 56 T V N LN L N ++++ +W +K + HE +E+ + D Sbjct: 11 TLVENSLNTQLSNWFLLYSKLHRF--------HWYVKGPHFFTLHEKFEELYDHAAETVD 62 Query: 57 RYIERILFLEGLPN--LQDLGKL------NIGEDVEEMLRSDLALELDGAKNLREAIGYA 108 ER+L + G P +++ + EM+++ + + + IG A Sbjct: 63 TIAERLLAIGGQPVATVKEYTEHASITDGGNETSASEMVQALVNDYKQISSESKFVIGLA 122 Query: 109 DSVHDYVSRDMMIEILRDEEGHIDWLETEL 138 + D + D+ + ++ + E + L + L Sbjct: 123 EENQDNATADLFVGLIEEVEKQVWMLSSYL 152
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 31.6 bits (71), Expect = 0.015 Identities = 14/60 (23%), Positives = 24/60 (40%) Query: 181 ATEISETSNPQSCTSAPQPSPDVKPAPDVKPAPDVQPAPADKSNDNYAVVAWKGQEGSST 240 A + E + ++ ++ +PD KP P P K N N A + ++ ST Sbjct: 449 AKQAEELAKLRAGKASDSQTPDAKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQLPST 508
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 613 bits (1583), Expect = 0.0 Identities = 178/698 (25%), Positives = 304/698 (43%), Gaps = 81/698 (11%) Query: 9 RYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAAT 68 + NIG+ AH+DAGKTT TE +L+ +G ++G V G D E++RGITI + T Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 69 TAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWR 128 + W ++NIIDTPGH+DF EV RS+ VLDGA+++ A GVQ Q+ ++ Sbjct: 62 SFQWEN-------TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFH 114 Query: 129 QANKYKVPRIAFVNKMDRMGANFLKVVNQIKTRLGANPVPLQLAIGAEEHFTGVVDLVKM 188 K +P I F+NK+D+ G + V IK +L A V Q V M Sbjct: 115 ALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQ----------KVELYPNM 164 Query: 189 KAINWNDADQGVTFEYEDIPADMVELANEWHQNLIESAAEASEELMEKYLGGEELTEAEI 248 N+ +++Q ++ E +++L+EKY+ G+ L E+ Sbjct: 165 CVTNFTESEQ------------------------WDTVIEGNDDLLEKYMSGKSLEALEL 200 Query: 249 KGALRQRVLNNEIILVTCGSAFKNKGVQAMLDAVIDYLPSPVDVPAINGILDDGKDTPAE 308 + R N + V GSA N G+ +++ + + S Sbjct: 201 EQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSSTH----------------- 243 Query: 309 RHASDDEPFSALAFKIATDPFVGNLTFFRVYSGVVNSGDTVLNSVKAARERFGRIVQMHA 368 FKI L + R+YSGV++ D+V S K + + + Sbjct: 244 ---RGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEK-EKIKITEMYTSIN 299 Query: 369 NKREEIKEVRAGDIAAAIG----LKDVTTGDTLCDPDAPIILERMEFPEPVISIAVEPKT 424 + +I + +G+I L V GDT P ER+E P P++ VEP Sbjct: 300 GELCKIDKAYSGEIVILQNEFLKLNSV-LGDTKLLPQR----ERIENPLPLLQTTVEPSK 354 Query: 425 KADQEKMGLALGRLAKEDPSFRVWTDEESNQTIIAGMGELHLDIIVDRMKREFNVEANVG 484 +E + AL ++ DP R + D +++ I++ +G++ +++ ++ +++VE + Sbjct: 355 PQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIK 414 Query: 485 KPQVAYRETIRQKVTDVEGKHAKQSGGRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGV 544 +P V Y E +K E + + + + + PL GS G ++ + + G Sbjct: 415 EPTVIYMERPLKK---AEYTIHIEVPPNPFWASIGLSVSPLPLGS---GMQYESSVSLGY 468 Query: 545 IPGEYIPAVDKGIQEQLKAGPLAGYPVVDMGIRLHFGSYHDVDSSELAFKLAASIAFKEG 604 + + AV +GI+ + G L G+ V D I +G Y+ S+ F++ A I ++ Sbjct: 469 LNQSFQNAVMEGIRYGCEQG-LYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQV 527 Query: 605 FKKAKPVLLEPIMKVEVETPEENTGDVIGDLSRRRGMLKGQESEVTGVKIHAEVPLSEMF 664 KKA LLEP + ++ P+E D + + + + V + E+P + Sbjct: 528 LKKAGTELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKNNEVILSGEIPARCIQ 587 Query: 665 GYATQLRSLTKGRASYTMEFLKYDEAPSNVAQAVIEAR 702 Y + L T GR+ E Y + V + R Sbjct: 588 EYRSDLTFFTNGRSVCLTELKGYHVT---TGEPVCQPR 622
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 29.0 bits (65), Expect = 0.021 Identities = 14/62 (22%), Positives = 29/62 (46%), Gaps = 1/62 (1%) Query: 160 ASSVEDLVTQTLEFTIEEVNADRNV-SNNAKNRQIVLNLYEKGIFDIKDAINQVADRLNI 218 A +V+D VTQ +E + ++ + S + + + L + D A QV ++L + Sbjct: 54 AQTVQDTVTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQL 113 Query: 219 SK 220 + Sbjct: 114 AT 115
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 134 bits (339), Expect = 1e-40 Identities = 80/226 (35%), Positives = 125/226 (55%), Gaps = 9/226 (3%) Query: 28 AAKPATAADSKAAFKNDDQKSAYALGASLGRYMENSLKEQEKLGIKLDKDQLIAGVQDAF 87 A A AA + D K +Y++GA LG K + GI ++ D L G+QD Sbjct: 14 AMSTAMAATDATSLTTDKDKLSYSIGADLG-------KNFKNQGIDINPDVLAKGMQDGM 66 Query: 88 A-DKSKLSDQEIEQTLQAFEARVKSSAQAKMEKDAADNEAKGKEYREKFAKEKGVKTSST 146 + + L++++++ L F+ + + A+ K A +N+AKG + + G+ + Sbjct: 67 SGAQLILTEEQMKDVLSKFQKDLMAKRSAEFNKKAEENKAKGDAFLSANKSKPGIVVLPS 126 Query: 147 GLVYQVVEAGKGEAPKDSDTVVVNYKGTLIDGKEFDNSYTRGEPLSFRLDGVIPGWTEGL 206 GL Y++++AG G P SDTV V Y GTLIDG FD++ G+P +F++ VIPGWTE L Sbjct: 127 GLQYKIIDAGTGAKPGKSDTVTVEYTGTLIDGTVFDSTEKAGKPATFQVSQVIPGWTEAL 186 Query: 207 KNIKKGGKIKLVIPPELAYGKAGVPG-IPPNSTLVFDVELLDVKPA 251 + + G ++ +P +LAYG V G I PN TL+F + L+ VK A Sbjct: 187 QLMPAGSTWEVFVPADLAYGPRSVGGPIGPNETLIFKIHLISVKKA 232
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 30.7 bits (69), Expect = 0.021 Identities = 13/69 (18%), Positives = 29/69 (42%), Gaps = 6/69 (8%) Query: 261 TAIDPFKGLLLG---LFFISVGMSLNLGVLYTHL-LWVVISVVVLVAVKILVLYLLARLY 316 A+ P L + L+FIS + L +++ + W +++ V+ ++ L Sbjct: 318 AAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKA-- 375 Query: 317 GVRSSERMQ 325 S +M+ Sbjct: 376 QYTSMAKMR 384
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 31.9 bits (72), Expect = 0.001 Identities = 32/135 (23%), Positives = 51/135 (37%), Gaps = 16/135 (11%) Query: 11 YAHPESQDSVANRVLLKPATQLSNVTVHDLYAHYPDFFIDIPREQALLREHEVIVFQH-- 68 Y P + D N+V P + + +HD+ ++ D F L + + Sbjct: 9 YQMPTASDMPQNKVSWVPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCV 68 Query: 69 ----PLYTYSCPALLKEWLDRVLSRGFASGPGGNQLAGKYWRSVITTGEPESA------Y 118 P+ + P DR L F GPG N +G Y +IT PE + Sbjct: 69 QLGIPVVYTAQPGSQNP-DDRALLTDFW-GPGLN--SGPYEEKIITELAPEDDDLVLTKW 124 Query: 119 RYDALNRYPMSDVLR 133 RY A R + +++R Sbjct: 125 RYSAFKRTNLLEMMR 139
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 32.7 bits (74), Expect = 0.005 Identities = 28/152 (18%), Positives = 54/152 (35%), Gaps = 22/152 (14%) Query: 504 KVEPFDGDLEDYQQWLSDVQKQENQTDEAPKENANSAQARKDQKRREAELRAQTQPLRKE 563 + D + ++ E + + ++ R+ +R R + L E Sbjct: 272 AMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAE 331 Query: 564 IARLEKEME---------------------KLNAQLAQAEEKLGDSELYDQSRKAELTAC 602 +LE++ + +L A+ + EE+ SE QS + +L A Sbjct: 332 HQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDAS 391 Query: 603 LQQQASAKSGLEECEMAWLEAQEQLEQMLLEG 634 + + + LEE L A E+L + L E Sbjct: 392 REAKKQVEKALEEANSK-LAALEKLNKELEES 422 Score = 32.0 bits (72), Expect = 0.008 Identities = 13/125 (10%), Positives = 39/125 (31%), Gaps = 7/125 (5%) Query: 513 EDYQQWLSDVQKQENQTDEAPKENANSAQARKDQKRREAELRAQTQPLRKEIARLEKEME 572 + + ++ + E A A + D ++ + +++ Sbjct: 127 KALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFST-------ADSAKIK 179 Query: 573 KLNAQLAQAEEKLGDSELYDQSRKAELTACLQQQASAKSGLEECEMAWLEAQEQLEQMLL 632 L A+ A E + + E + TA + + ++ + ++ LE + Sbjct: 180 TLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMN 239 Query: 633 EGQSN 637 ++ Sbjct: 240 FSTAD 244
>PF07299#Fibronectin-binding protein (FBP) Length = 219 Score = 31.8 bits (72), Expect = 0.002 Identities = 10/46 (21%), Positives = 21/46 (45%), Gaps = 2/46 (4%) Query: 71 PEANDFGLLEQTFIEYGQSGKGKSRKYLHTYDEAVPWNQVPGTFTP 116 P+ + + E ++ KG SRK++ ++ + + GTF Sbjct: 112 PDMEELDMKELSY--LSWIDKGSSRKFIIAKNDKNKFVGLQGTFQS 155
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 29.0 bits (65), Expect = 0.033 Identities = 23/98 (23%), Positives = 38/98 (38%), Gaps = 18/98 (18%) Query: 226 ENLLFTHRGLSGPAVLQISSYWQPGEFVSINLLPDVDLETFL--NEQRNAHPNQSLKNTL 283 E + RG GP +L + ++ + + + L T + N Q A N LK L Sbjct: 63 EAITLRERGWKGP-ILMLEGFFHAQD---LEIYDQHRLTTCVHSNWQLKALQNARLKAPL 118 Query: 284 AVHL------------PKRLVERLQQLGQIPDVSLKQL 309 ++L P R++ QQL + +V L Sbjct: 119 DIYLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTL 156
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 42.9 bits (101), Expect = 2e-06 Identities = 48/275 (17%), Positives = 94/275 (34%), Gaps = 32/275 (11%) Query: 44 PVSQVAFSFGLLSLGLAIS----SSVAGKLQERFGVKRVTMASGILLGLGFFLTAHSDNL 99 + V +G+L A+ + V G L +RFG + V + S + + + A + L Sbjct: 37 HSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFL 96 Query: 100 MMLWLS---AGVLVGLADGAGYLL----TLSNCVKWFPERKGLISAFAIGSYGLGSLGFK 152 +L++ AG+ AG + + F + LG Sbjct: 97 WVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGG---- 152 Query: 153 FIDTQLLETVGLEKTFVIWGAIALLMIVFGATLMKDAPKQEVKTSNGVVEKDYTLAESMR 212 L+ F A+ L + G L+ ++ K E + R Sbjct: 153 -----LMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWAR 207 Query: 213 --KPQYWMLAVMFLTACMSG----LYVIGVAKDIAQSLAHLDVVSAANAVTVISIAN-LS 265 ++AV F+ + L+VI + H D + ++ I + L+ Sbjct: 208 GMTVVAALMAVFFIMQLVGQVPAALWVI-----FGEDRFHWDATTIGISLAAFGILHSLA 262 Query: 266 GRLVLGILSDKIARIRVITIGQVISLVGMAALLFA 300 ++ G ++ ++ R + +G + G L FA Sbjct: 263 QAMITGPVAARLGERRALMLGMIADGTGYILLAFA 297 Score = 36.3 bits (84), Expect = 2e-04 Identities = 37/155 (23%), Positives = 64/155 (41%), Gaps = 9/155 (5%) Query: 241 AQSLAHLDVVSAANAVTVISIANLSGRLVLGILSDKIARIRVITIGQVISLVGMAALLFA 300 AH ++ A A+ + A + G L SD+ R V+ + + V A + A Sbjct: 39 NDVTAHYGILLALYALMQFACAPVLGAL-----SDRFGRRPVLLVSLAGAAVDYAIMATA 93 Query: 301 PLNAVTFFAAIACVAFNFGGTITVFPSLVSEFFGLNNLAKNYGVIYLGFGIGSICGSIIA 360 P V + I VA G T V + +++ + A+++G + FG G + G ++ Sbjct: 94 PFLWVLYIGRI--VAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLG 151 Query: 361 SLFGGF--YVTFYVIFALLILSLALSTTIRQPEQK 393 L GGF + F+ AL L+ + K Sbjct: 152 GLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHK 186
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 27.5 bits (61), Expect = 0.048 Identities = 19/90 (21%), Positives = 37/90 (41%), Gaps = 13/90 (14%) Query: 119 SMYNEFGDSTTTLTDPLWHASVSTLGWRVDSRLGDLRPWAQISYNQQFGENIWKAQSGLS 178 S+ + D+ + H S + + + R G++ P ++SY F + Sbjct: 228 SVAVQQQDAKLV-EENYSHNSQTEVAATLAYRFGNVTP--RVSYAHGFKGSF-------- 276 Query: 179 RMTATNQNGNWLDVTVGADMLLNQNIAAYA 208 ATN N ++ V VGA+ ++ +A Sbjct: 277 --DATNYNNDYDQVVVGAEYDFSKRTSALV 304
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.1 bits (83), Expect = 2e-05 Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 5/52 (9%) Query: 76 VAPKAVRRGIGKALM----QYVQQRHP-HLMLEVYQKNQPAINFYQAQGFHI 122 VA ++G+G AL+ ++ ++ H LMLE N A +FY F I Sbjct: 97 VAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFII 148
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 113 bits (285), Expect = 2e-32 Identities = 41/122 (33%), Positives = 62/122 (50%), Gaps = 11/122 (9%) Query: 108 LNMPNNVTFDSSSATLKPAGANTLTGVAMVLKEY--PKTAVNVIGYTDSTGGHDLNMRLS 165 + ++V F+ + ATLKP G L + L +V V+GYTD G N LS Sbjct: 215 FTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLS 274 Query: 166 QQRADSVASALITQGVDASRIRTQGLGPANPIASNSTAEGK---------AQNRRVEITL 216 ++RA SV LI++G+ A +I +G+G +NP+ N+ K A +RRVEI + Sbjct: 275 ERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEV 334 Query: 217 SP 218 Sbjct: 335 KG 336
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 59.9 bits (145), Expect = 6e-12 Identities = 41/184 (22%), Positives = 81/184 (44%), Gaps = 1/184 (0%) Query: 5 RNVNLLLMLVLLVAVGQMAQTIYIPAIADMARDLNVREGAVQSVMGAYLLTYGVSQLFYG 64 R+ +L+ L +L + + + ++ D+A D N + V A++LT+ + YG Sbjct: 11 RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYG 70 Query: 65 PISDRVGRRPVILVGMSIFMLATLVA-VTTSSLTVLIAASAMQGMGTGVGGVMARTLPRD 123 +SD++G + ++L G+ I +++ V S ++LI A +QG G + + Sbjct: 71 KLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVAR 130 Query: 124 LYERTQLRHANSLLNMGILVSPLLAPLIGGLLDTMWNWRACYLFLLVLCAGVTFSMARWM 183 + A L+ + + + P IGG++ +W L ++ V F M Sbjct: 131 YIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLK 190 Query: 184 PETR 187 E R Sbjct: 191 KEVR 194
>PF06580#Sensor histidine kinase Length = 349 Score = 37.5 bits (87), Expect = 9e-05 Identities = 49/262 (18%), Positives = 104/262 (39%), Gaps = 43/262 (16%) Query: 204 ILFALATVLLA-SVLSFFW-YRRYLRSRQLLQDEMKRKEKLVALGHLAAGV-AHEIRNPL 260 I+F + V S+L F W + + + ++ Q +M + L L A + H + N L Sbjct: 120 IIFNVVVVTFMWSLLYFGWHFFKNYKQAEIDQWKMASMAQEAQLMALKAQINPHFMFNAL 179 Query: 261 SSIKGLAKYFAERAPAGGEAHQLAQVM---AKEADRLNRVVSELLELVKPTHLALQAVDL 317 ++I+ L +A L+++M + ++ +++ L +V ++L L ++ Sbjct: 180 NNIRALILEDPTKAREM--LTSLSELMRYSLRYSNARQVSLADELTVVD-SYLQLASIQF 236 Query: 318 NTLINHSLQLVSQDANSREIQLRFTANDTLPEIQADPDRLTQVLL-NLYLNAIQAIGQHG 376 + Q+ + ++Q+ P L Q L+ N + I + Q G Sbjct: 237 EDRLQFENQI---NPAIMDVQV--------------PPMLVQTLVENGIKHGIAQLPQGG 279 Query: 377 VISVTASESGAGVKISVTDSGKGIAADQLDAIFTPYFTTKAEGTGLGLAVVHNIVEQHGG 436 I + ++ V + V ++G + E TG GL V ++ G Sbjct: 280 KILLKGTKDNGTVTLEVENTGSLALKNT------------KESTGTGLQNVRERLQMLYG 327 Query: 437 ---TIQVASQEGKGSTFTLWLP 455 I+++ ++GK + +P Sbjct: 328 TEAQIKLSEKQGKV-NAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 524 bits (1351), Expect = 0.0 Identities = 183/468 (39%), Positives = 253/468 (54%), Gaps = 35/468 (7%) Query: 8 ILVVDDDISHCTILQALLRGWGYNVALANSGRQALEQVREQVFDLVLCDVRMAEMDGIAT 67 ILV DDD + T+L L GY+V + ++ + DLV+ DV M + + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 68 LKEIKALNPAIPVLIMTAYSSVETAVEALKTGALDYLIKPLDFDNLQATLEKALAHTHSI 127 L IK P +PVL+M+A ++ TA++A + GA DYL KP D L + +ALA Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRR 125 Query: 128 DAETPAVTASQFGMVGKSPAMQHLLSEIALVAPSEATVLIHGDSGTGKELVARAIHASSA 187 ++ + +VG+S AMQ + +A + ++ T++I G+SGTGKELVARA+H Sbjct: 126 PSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGK 185 Query: 188 RSEKPLVTLNCAALNESLLESELFGHEKGAFTGADKRREGRFVEADGGTLFLDEIGDISP 247 R P V +N AA+ L+ESELFGHEKGAFTGA R GRF +A+GGTLFLDEIGD+ Sbjct: 186 RRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPM 245 Query: 248 MMQVRLLRAIQEREVQRVGSNQIISVDVRLIAATHRDLAAEVNAGRFRQDLYYRLNVVAI 307 Q RLLR +Q+ E VG I DVR++AAT++DL +N G FR+DLYYRLNVV + Sbjct: 246 DAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPL 305 Query: 308 EVPSLRQRREDIPLLAGHFLQRFAERNRKAVKGFTPQAMDLLIHYDWPGNIRELENAVER 367 +P LR R EDIP L HF+Q+ + VK F +A++L+ + WPGN+RELEN V R Sbjct: 306 RLPPLRDRAEDIPDLVRHFVQQAEKEGLD-VKRFDQEALELMKAHPWPGNVRELENLVRR 364 Query: 368 AVVLLTGEYISERELPLAIASTPIPLGQSQDIQP-------------------------- 401 L + I+ + + S + Sbjct: 365 LTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALP 424 Query: 402 --------LVEVEKEVILAALEKTGGNKTEAARQLGITRKTLLAKLSR 441 L E+E +ILAAL T GN+ +AA LG+ R TL K+ Sbjct: 425 PSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRE 472
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 31.3 bits (71), Expect = 7e-04 Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 9/62 (14%) Query: 37 IANFFVAEKVLQDLVLQLHPRSTWHSFLPAKRMDIVVSALEMNEGGLSQVEERILHEVVA 96 IA+FFV EK+LQ + Q+H S P+ R+ + V G +QVE R + E Sbjct: 81 IADFFVTEKMLQHFIKQVHSNSF---MRPSPRVLVCVPV------GATQVERRAIRESAQ 131 Query: 97 GA 98 GA Sbjct: 132 GA 133
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 34.9 bits (80), Expect = 4e-05 Identities = 16/54 (29%), Positives = 21/54 (38%), Gaps = 5/54 (9%) Query: 78 IDPDVRGCGVGRVLVEHALSMAPE-----LTTNVNEQNEQAVGFYKKVGFKVTG 126 + D R GVG L+ A+ A E L + N A FY K F + Sbjct: 97 VAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGA 150
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 32.3 bits (73), Expect = 0.004 Identities = 14/58 (24%), Positives = 23/58 (39%) Query: 289 ETSTPDLELARRFAQAIHAKYPGKLLAYNCSPSFNWQKNLDDKTIASFQQQLSDMGYK 346 ET+ PD+ L A P L Y + N D +T + + QL+++ Sbjct: 544 ETTKPDMTLKEALKIAFGFNEPNGNLQYQGKDITEFDFNFDQQTSQNIKNQLAELNAT 601
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 30.4 bits (68), Expect = 0.007 Identities = 21/95 (22%), Positives = 38/95 (40%), Gaps = 3/95 (3%) Query: 20 AAGTVKVFSNGSSEAKTLTGAEHLIDLVGQPRLANSWWPGAVISEELATAAALRQQQALL 79 A + + + LT + L D+V + N+ + A AA++ + L Sbjct: 73 AKAAAEAQAKAKANRDALT--QRLKDIVNEALRHNASRTPSATELAHANNAAMQAEDERL 130 Query: 80 TRLAEQGADSSADDAAAINALRQQIQALKVTGRQK 114 RLA+ + + AA A ++ Q K R+K Sbjct: 131 -RLAKAEEKARKEAEAAEKAFQEAEQRRKEIEREK 164
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 35.6 bits (82), Expect = 4e-04 Identities = 20/87 (22%), Positives = 42/87 (48%), Gaps = 3/87 (3%) Query: 279 VIGVMLSIFQQFVGINVVLYYAPEVFKTLGASTDIALLQTIIVGVINLTFTVLAIMT--- 335 +I ++ ++ VGI +++ P + + L S D+ I++ + L A + Sbjct: 7 LIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGAL 66 Query: 336 VDKFGRKPLQIIGALGMAIGMFSLGTA 362 D+FGR+P+ ++ G A+ + TA Sbjct: 67 SDRFGRRPVLLVSLAGAAVDYAIMATA 93
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 31.1 bits (70), Expect = 0.011 Identities = 22/124 (17%), Positives = 43/124 (34%), Gaps = 21/124 (16%) Query: 128 GDEWQLALSDGETGKNYLSDAFKFGGEQKLQLKETTAQPEGERANLRVITQNRQALSDIT 187 ++WQ+ T DA L+L T + L+ + A+ ++ Sbjct: 367 NNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPV---SDAIVNMD 423 Query: 188 AILPDGNKVMMSSLRQFSGTQPLYTLDGDGTLTNNQSGVKYRPNNQ--------IGFYQS 239 ++ D K+ M+S GD N Q+ + + N++ Y S Sbjct: 424 VLITDEAKIAMAS----------EEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYAS 473 Query: 240 ITAD 243 + +D Sbjct: 474 LVSD 477
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 756 bits (1953), Expect = 0.0 Identities = 396/396 (100%), Positives = 396/396 (100%) Query: 1 MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIK 60 MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIK Sbjct: 1 MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIK 60 Query: 61 VTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTW 120 VTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTW Sbjct: 61 VTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTW 120 Query: 121 DAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEP 180 DAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEP Sbjct: 121 DAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEP 180 Query: 181 YFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAE 240 YFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAE Sbjct: 181 YFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAE 240 Query: 241 AAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKE 300 AAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKE Sbjct: 241 AAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKE 300 Query: 301 LAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIP 360 LAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIP Sbjct: 301 LAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIP 360 Query: 361 QMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITK 396 QMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITK Sbjct: 361 QMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITK 396
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 28.8 bits (64), Expect = 0.016 Identities = 14/45 (31%), Positives = 20/45 (44%), Gaps = 4/45 (8%) Query: 145 PLLVSHGIALGCLVSTILGLPAWAERRLRLRNCSISRVDYQESLW 189 P +V GIA G V T+ GL W ++ N D + +W Sbjct: 42 PAIVG-GIATGAAVGTVSGLLGWGLKQAEEAN---KTPDKPDKVW 82
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 88.3 bits (219), Expect = 2e-22 Identities = 34/139 (24%), Positives = 60/139 (43%) Query: 1 MQRETVWLVEDEQGIADTLVYMLQQEGFAVEVFERGLPVLDKARQQAPDVMILDVGLPDI 60 M T+ + +D+ I L L + G+ V + + D+++ DV +PD Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 SGFELCRQLLALHPALPVLFLTARSEEVDRLLGLEIGADDYVAKPFSPREVCARVRTLLR 120 + F+L ++ P LPVL ++A++ + + E GA DY+ KPF E+ + L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 121 RVKKFSSPSPVIRIGHFEL 139 K+ S L Sbjct: 121 EPKRRPSKLEDDSQDGMPL 139
>PF06580#Sensor histidine kinase Length = 349 Score = 32.9 bits (75), Expect = 0.002 Identities = 40/182 (21%), Positives = 73/182 (40%), Gaps = 40/182 (21%) Query: 312 LRQARLENRQEVVLTVVDVAALFR---RVSEARTVQLAE--KNITLHVM--------PTE 358 +R LE+ + + ++ L R R S AR V LA+ + ++ + Sbjct: 182 IRALILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQ 241 Query: 359 VNVAAEPALLEQALGNLL-----DNA----IDFTPESGRITLSAEVDQEHVALKVLDTGS 409 PA+++ + +L +N I P+ G+I L D V L+V +TGS Sbjct: 242 FENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGS 301 Query: 410 GIPDYALSRIFERFYSLPRANGQKSSGLGLAFVSE-VARLFNGEVTLR-NVQEGGVLASL 467 N ++S+G GL V E + L+ E ++ + ++G V A + Sbjct: 302 LALK----------------NTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMV 345 Query: 468 RL 469 + Sbjct: 346 LI 347
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 81.8 bits (202), Expect = 4e-20 Identities = 30/122 (24%), Positives = 60/122 (49%), Gaps = 1/122 (0%) Query: 1 MQTPHILIVEDELVTRNTLKSIFEAEGYDVFEATDGAEMHQILSEYDINLVIMDINLPGK 60 M IL+ +D+ R L GYDV ++ A + + ++ D +LV+ D+ +P + Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 NGLLLARELRE-QANVALMFLTGRDNEVDKILGLEIGADDYITKPFNPRELTIRARNLLS 119 N L +++ + ++ ++ ++ ++ + I E GA DY+ KPF+ EL L+ Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 120 RT 121 Sbjct: 121 EP 122