>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 72.9 bits (179), Expect = 2e-17 Identities = 27/121 (22%), Positives = 52/121 (42%), Gaps = 11/121 (9%) Query: 8 LILDDDDVFAQTLARALTRRGFAPQIAHTGGEALSLARQTPFAYVTVDLHLAASDRGLMP 67 L+ DDD L +AL+R G+ +I V D+ MP Sbjct: 7 LVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVV--------MP 58 Query: 68 HGGTDSGLHWIAPLRQALPEARMLVLTGYASIATAVQAVKLGADEYLAKPANVDSILLAL 127 + + +++A P+ +LV++ + TA++A + GA +YL KP ++ ++ + Sbjct: 59 DE---NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGII 115 Query: 128 Q 128 Sbjct: 116 G 116 Score = 45.2 bits (107), Expect = 5e-08 Identities = 12/47 (25%), Positives = 22/47 (46%) Query: 141 ENPAPLSVARLEWEHIQRVLSEHGGNISATARALNMHRRTLQRKLGK 187 +A +E+ I L+ GN A L ++R TL++K+ + Sbjct: 426 SGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRE 472
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.6 bits (69), Expect = 0.015 Identities = 11/36 (30%), Positives = 18/36 (50%), Gaps = 3/36 (8%) Query: 50 TPKNILMIGPTGVGKTEIAR---RLAKLADAPFIKI 82 T +++ G +G GK +AR K + PF+ I Sbjct: 159 TDLTLMITGESGTGKELVARALHDYGKRRNGPFVAI 194
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 31.3 bits (70), Expect = 0.006 Identities = 35/133 (26%), Positives = 62/133 (46%), Gaps = 8/133 (6%) Query: 72 DIVGAQIDAVAQDIGVDAAKTGMLGSPAVVEAIVSALARHPIAALVVDPVMVSTSGAQLG 131 +++G I + +GVD M GS +V AIV+A+A +A +VV V+ + A+LG Sbjct: 383 ELIGKAITKALEGLGVDKKTAEMAGS--IVGAIVAAIAM--VAVIVVVAVVGKGAAAKLG 438 Query: 132 SDATAQAMAKWLFPRALLITPNLPE-ASALLGRAVRTADDMLPAARDLLTLGSRAVL--L 188 +A ++ M + + + L + S L + ++ L + L + A+ L Sbjct: 439 -NALSKMMGETIKKLVPNVLKQLAQNGSKLFTQGMQRITSGLGNVGSKMGLQTNALSKEL 497 Query: 189 KGGHLADVAIPGE 201 G L VA+ E Sbjct: 498 VGNTLNKVALGME 510
>INTIMIN#Intimin signature. Length = 939 Score = 27.7 bits (61), Expect = 0.011 Identities = 18/54 (33%), Positives = 26/54 (48%) Query: 56 NGRDALTITANGPFVFAATVPFNGGYTVTIGTQPSSASCAVSNGSGIATADVTS 109 +G +A+T TA A + + GT SA+ A +NGSG AT + S Sbjct: 573 DGTEAITYTATVKKNGVAQANVPVSFNIVSGTAVLSANSANTNGSGKATVTLKS 626
>INTIMIN#Intimin signature. Length = 939 Score = 39.3 bits (91), Expect = 1e-04 Identities = 69/383 (18%), Positives = 121/383 (31%), Gaps = 27/383 (7%) Query: 400 TPTSAGTFSFTVTATDSSTGTGPFSATSGTLSLTIAAPTITVSPSTLTSPTVGAASSQSV 459 + + T A D + S+ + L++T+ + V +T T S+++ Sbjct: 518 VQGGSNVYKVTARAYDRNGN----SSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKAD 573 Query: 460 SASGGTSPYTYA---VTAGALPAGMSLSSAGTLSGTPTA--GGAFSFTATATDST-GGTG 513 T T V +P ++ S + +A G+ T T G Sbjct: 574 GTEAITYTATVKKNGVAQANVPVSFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVV 633 Query: 514 PYTGSRSYTLTVNAPTLSITPAAGSLSATSGVAYSQAFVAASGTAPYTYALSVNSGALPT 573 + T +NA + + ++ + + + A+G TY + V G P Sbjct: 634 VSAKTAEMTSALNANAVIFVD--QTKASITEIKADKTTAVANGQDAITYTVKVMKGDKPV 691 Query: 574 G---LSFNTATGMLSGTPTTAGTANFTVTGTDSSTGTGPYTVSATYTLTTSAPTISLAPA 630 ++F T G LS + T + T +ST G VSA S + + Sbjct: 692 SNQEVTFTTTLGKLSNSTEKTDTNGYA-KVTLTSTTPGKSLVSA----RVSDVAVDVKAP 746 Query: 631 TLTGATVGTAYSQSVTASG-GATPYTYAITSGALPAGLNLNTGTGALTGTPTAAGTFSFT 689 + T T ++ G G + L + G G T S Sbjct: 747 EVEFFTTLTIDDGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPAIAS-- 804 Query: 690 VRGTDANAFSGTRSYSLTVAAPTIALTPTTLAGATVSSAYSQSVAASGGTAPYTYAVTSG 749 DA++ T ++ + A T+++ S V Y AV + Sbjct: 805 ---VDASSGQVTLKEK-GTTTISVISSDNQTATYTIATPNSLIVPNMSKRVTYNDAVNTC 860 Query: 750 ALPAGLSLSSAGVLSGTPTAGGS 772 G SS L A G+ Sbjct: 861 KNFGGKLPSSQNELENVFKAWGA 883 Score = 32.7 bits (74), Expect = 0.015 Identities = 62/388 (15%), Positives = 112/388 (28%), Gaps = 57/388 (14%) Query: 237 TVTTSGGTSATSSADQFTYAAPPTANASSATVA----HGSSSNAITLSISGGTPTSVAVS 292 + SG SA +N T +G+SSN + L+I+ V Sbjct: 498 QIQHSGSQSAQDYQAILPAYVQGGSNVYKVTARAYDRNGNSSNNVLLTIT--------VL 549 Query: 293 TAASHGTATASGTSITYTPTASYSGTDTFAYTASNAGGTSAAATVTITVSSATVSYAPAS 352 + +A GT+ YTA+ A A V ++ + + Sbjct: 550 SNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKNGVAQANVPVSFNIVS------- 602 Query: 353 PAAGTVGTAYSQSVASASGGTSPYTYALASGSLPPGLTLSTGGTLSGTPT---SAGTFSF 409 GTA + ++ + G+ T L S PG + + T T +A F Sbjct: 603 ------GTAVLSANSANTNGSGKATVTLKSDK--PGQVVVSAKTAEMTSALNANAVIFVD 654 Query: 410 TVTATDSSTGTGPFSATSGTLSLTIAAPTITVSPSTLTSPTVGAASSQSVSASGGTSPYT 469 A+ + +A + IT + + + + + + G + Sbjct: 655 QTKASITEIKADKTTAVANGQD------AITYTVKVMKGDKPVSNQEVTFTTTLGKLSNS 708 Query: 470 YAVTAGALPAGMSLSSAGTLSGTPTA---GGAFSFTATATDSTGGTGPYTGSRSYTLTVN 526 T A ++L+S +A A A + G N Sbjct: 709 TEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDG--------N 760 Query: 527 APTLSITPAAGSLSATSGVAYSQAFVAASGTAPYTYALSVNSGALPTGLSFNTATGMLSG 586 + + A+ G YT+ + + A + SG Sbjct: 761 IEIVGTGVKGKLPTVWLQYGQVN-LKASGGNGKYTWRSANPAIA---------SVDASSG 810 Query: 587 TPTTAGTANFTVTGTDSSTGTGPYTVSA 614 T T++ S T YT++ Sbjct: 811 QVTLKEKGTTTISVISSDNQTATYTIAT 838
>PERTACTIN#Pertactin signature. Length = 922 Score = 28.9 bits (64), Expect = 0.005 Identities = 18/68 (26%), Positives = 23/68 (33%), Gaps = 4/68 (5%) Query: 47 RMAPPPRTMQSINQDLQQHRRPSGKRPDGAPGRGRKPPPDSANADGKPPAPPDGPPPSDA 106 R+A S L + P +P PG P P +PP PP P Sbjct: 551 RLAANGNGQWS----LVGAKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPE 606 Query: 107 PPPDGPPS 114 P PP+ Sbjct: 607 APAPQPPA 614
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 45.6 bits (108), Expect = 2e-07 Identities = 78/316 (24%), Positives = 125/316 (39%), Gaps = 30/316 (9%) Query: 69 LMDRFTPPLIGR------RRGWLVLTQAGLAASIAAMAFCPPHAALWALAGLAVLVAFLS 122 LM P++G RR L+++ AG A A MA P LW L + +VA ++ Sbjct: 54 LMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAP---FLWVLY-IGRIVAGIT 109 Query: 123 ASQDIVFDAYSTDVLHASERGVGAAVKVLGYRLAMLVSGGLALWLADRVMGWSS--MYLL 180 + V AY D+ ER + G+ A G +A + +MG S Sbjct: 110 GATGAVAGAYIADITDGDER-----ARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFF 164 Query: 181 MAGLMAL--FVLATLWSPEPEAAARPPRSLQEAVVGPLRDFFARRGAWALLALIVLYKLG 238 A + F+ PE R P + + PL F RG + AL+ ++ + Sbjct: 165 AAAALNGLNFLTGCFLLPESHKGERRPLRREA--LNPLASFRWARGMTVVAALMAVFFIM 222 Query: 239 DAFAGSLSTTFLIRG---VGFSAGEVGIVNKTLGLVATIIGALYGGTLMVRLGLVRALLL 295 + ++I G + A +GI G++ ++ A+ G + RLG RAL+L Sbjct: 223 QLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALML 282 Query: 296 FGVLQAVSNLGYWVLAVTPQHLWTMALAIGIENLCGGMGTAAFVALLMALCNRSFSATQY 355 + ++L W MA I + GG+G A A+L + Sbjct: 283 GMIADGTG----YILLAFATRGW-MAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQ 337 Query: 356 ALLSALASIGRVYVGP 371 L+AL S+ + VGP Sbjct: 338 GSLAALTSLTSI-VGP 352
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 63.9 bits (155), Expect = 3e-14 Identities = 72/266 (27%), Positives = 109/266 (40%), Gaps = 24/266 (9%) Query: 6 NESPILPRIALVTGAARRVGRVIALALARQGWDV-AVHCHRSRAEADAVAAEIIAMGRRA 64 N I +IA +TGAA+ +G +A LA QG + AV + + E V + + A R A Sbjct: 2 NAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLE--KVVSSLKAEARHA 59 Query: 65 AVLQADLADEAAAGRLIADCTAALGTPTCLVNNASLFQYDVATSFSYASLDTHMRINVAA 124 AD+ D AA + A +G LVN A + + + S S + +N Sbjct: 60 EAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTG 119 Query: 125 PLLLARELHRVLAAEDGGAGEVRGVVVNLLDQKLDNLNPDFLSYTLSKAALATATTQLAQ 184 +R + + + G+ +V + +Y SKAA T L Sbjct: 120 VFNASRSVSKYMMDRRSGS------IVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGL 173 Query: 185 ALAPT-LRVVGVAPGATLVSWKQSE-----------SGFERAHKMA-PLGRSSTPEDIAE 231 LA +R V+PG+T + S G K PL + + P DIA+ Sbjct: 174 ELAEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIAD 233 Query: 232 AVCYLTTARA--VTGTTLFVDGGQHL 255 AV +L + +A +T L VDGG L Sbjct: 234 AVLFLVSGQAGHITMHNLCVDGGATL 259
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 62.3 bits (151), Expect = 7e-14 Identities = 35/211 (16%), Positives = 79/211 (37%), Gaps = 7/211 (3%) Query: 13 RPRGPVREDLRDRLLDIAVQRFARDGIDATTMAAIAREAGVTAPMVHYHFATRDQLLDAV 72 R ++ R +LD+A++ F++ G+ +T++ IA+ AGVT +++HF + L + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 73 VDMRLKPLIDEVMDPALTAIPDDGHAPELARIVAGAAQRMVAVASATPWFPTLWIREIAS 132 ++ + + ++ D L I+ + V ++ + Sbjct: 63 WELSESNIGELELEYQAKFPGDP--LSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 133 EGGQLRERVFARIALERATVLVERIARAQAAGAVNAALEPTLVMVSVIGLAMLPLATRAL 192 + ++ + LE + + + A + A L ++ + L Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAA-IIMRGYISGLMEN-- 177 Query: 193 WGRLPHAETIDAQAIGRHVAALLLHGVGPAP 223 W P ++ D + R A+LL P Sbjct: 178 WLFAP--QSFDLKKEARDYVAILLEMYLLCP 206
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 57.1 bits (138), Expect = 3e-11 Identities = 40/357 (11%), Positives = 90/357 (25%), Gaps = 85/357 (23%) Query: 44 VASPVGGRLEHLGVQRGQTVSAGTPLFILESTDEAAARQQAAAQQQAAEAQLADLNLGRR 103 + ++ + V+ G++V G L L + A + + A + + R Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSR 158 Query: 104 VPEVDAV------------RAQLAQAVAADQLSATQRVRDEAQFRAGGIPQAQLDASRST 151 E++ + + + L Q + Q + + A R T Sbjct: 159 SIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLT 218 Query: 152 AQTNAQRVRELTNQLRI-----------------------AQLPARTDQIHAQSAQVEAA 188 R L+ + + +++ +Q+E Sbjct: 219 VLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQI 278 Query: 189 RAAVAQAQWRLDQKAQ------------------------------------KATQGGLV 212 + + A+ Q +A V Sbjct: 279 ESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKV 338 Query: 213 FD-TLYREGEWVGAGSPVVRMLPPANV-KVRFFVPEGVVGRLKPGQAVRIRCDG----CA 266 ++ EG V ++ ++P + +V V +G + GQ I+ + Sbjct: 339 QQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRY 398 Query: 267 AEVNATISYV---ASEAEYTPPVIYSNSRRDKLVFMVEARPAAADGPKLRPGQPVEV 320 + + + A E + V ++ L G V Sbjct: 399 GYLVGKVKNINLDAIEDQRLGLVFNVIISIEE-----NCLSTGNKNIPLSSGMAVTA 450
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 36.4 bits (84), Expect = 1e-04 Identities = 39/192 (20%), Positives = 80/192 (41%), Gaps = 8/192 (4%) Query: 194 GVILTMTMVMMT----GLAMTRERERGTMENLLATPVRPLEVMTGKIVPYIFIGLVQVSI 249 G++ T M T A R + T E +L T +R +++ G++ + + Sbjct: 72 GMVATSAMTAATFETIYAAFGRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAG 131 Query: 250 ILLAARFIFHVPFVGSAWMVYLAALL-FIVASLTVGITLSSLAQNQLQATQLTFFYFLPS 308 I + A + + ++ + + + AL ASL + +T + + + Q P Sbjct: 132 IGVVAAALGYTQWLSLLYALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVI--TPI 189 Query: 309 ILLSGFMFPFAGMPKWAQVIGDVLPMTYFHRLTRGILLKGNGWVELWPSIWPLLVFTAVV 368 + LSG +FP +P Q LP+++ L R I+L V++ + L ++ + Sbjct: 190 LFLSGAVFPVDQLPIVFQTAARFLPLSHSIDLIRPIMLGHPV-VDVCQHVGALCIYIVIP 248 Query: 369 MGIALRFYRKTL 380 ++ R+ L Sbjct: 249 FFLSTALLRRRL 260
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 35.2 bits (81), Expect = 5e-04 Identities = 30/190 (15%), Positives = 52/190 (27%), Gaps = 35/190 (18%) Query: 77 LDALVDEALRASPTVAQAAARLREAQAQA--DAQFGAVLPSVDGSASAVRQQVNPEAFGF 134 L AL EA + ARL + + Q + LP + Q V+ E Sbjct: 127 LTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEE--- 183 Query: 135 NTPKPGPFTLYSASLSVSYALDLFGGVRRALEASRAQVDMQRYELEAARLSLAGNVVTAA 194 V R + Q + + L+L Sbjct: 184 --------------------------VLRLTSLIKEQFSTWQNQKYQKELNLDK----KR 213 Query: 195 VRIASLDAQIATTQRLLAAQRDQLVITERRFGAGGVARVDVLSQRTQVAQTEATLPPLAQ 254 ++ A+I + L ++ +L +A+ VL Q + + L Sbjct: 214 AERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKS 273 Query: 255 QAAQARHRLS 264 Q Q + Sbjct: 274 QLEQIESEIL 283
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 49.4 bits (118), Expect = 6e-09 Identities = 27/131 (20%), Positives = 53/131 (40%), Gaps = 18/131 (13%) Query: 5 RIVLPGGAGLVGQNLVARLKARGYTNLVVLDK---------HEANLDVLRSVHPDITAVF 55 + ++ G AG +G ++ RL G+ +V +D +A L++L P Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQ-VVGIDNLNDYYDVSLKQARLELLA--QPGFQFHK 58 Query: 56 ADLAEPGDWARHFE--GADVVVMLQAQIGAP--TREP--FVRNNIDSTRCVLEVIKQHAI 109 DLA+ F + V + ++ P + +N+ +LE + + I Sbjct: 59 IDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKI 118 Query: 110 PYTVHISSSVV 120 + ++ SSS V Sbjct: 119 QHLLYASSSSV 129
>PF06580#Sensor histidine kinase Length = 349 Score = 38.3 bits (89), Expect = 5e-05 Identities = 28/140 (20%), Positives = 53/140 (37%), Gaps = 14/140 (10%) Query: 318 PLLDELELVPAIEWIAKNFRQRFGLIVNVHAQEMPMQERAAISVFRIVQEALNNVVRHA- 376 L DEL +V + +A +F + Q P + +VQ + N ++H Sbjct: 217 SLADELTVVDSYLQLASI---QFEDRLQFENQINPAIMDVQVPPM-LVQTLVENGIKHGI 272 Query: 377 ----DATRVEIEFVRLDDMLELSIQDNGRGWSGVPPAPGERKPLGLLGIRERARLL-GGQ 431 ++ ++ + + + L +++ G S E GL +RER ++L G + Sbjct: 273 AQLPQGGKILLKGTKDNGTVTLEVENTG---SLALKNTKESTGTGLQNVRERLQMLYGTE 329 Query: 432 ATIAHTP-DSGFRLSVRFPA 450 A I + V P Sbjct: 330 AQIKLSEKQGKVNAMVLIPG 349
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 81.4 bits (201), Expect = 3e-20 Identities = 30/116 (25%), Positives = 55/116 (47%), Gaps = 2/116 (1%) Query: 2 IRVMIADDHAVMRDGVRHILERAGDFEVACEASDGTQVLQLVRDHQPQVIVLDLSMPGRS 61 +++ADD A +R + L RAG ++V S+ + + + ++V D+ MP + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAG-YDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 62 GLELLRQLHDDHPTVRVLVLTMHAEEQYVARAFRAGAAAYLTKESAATELVTALQK 117 +LL ++ P + VLV++ +A GA YL K TEL+ + + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>OMADHESIN#Yersinia outer membrane adhesin signature. Length = 455 Score = 29.1 bits (64), Expect = 0.043 Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 7/77 (9%) Query: 190 TLIDGGLAQQVVGAS---AYAFWQRHVYAELGAYRTADQAFSV---FRAGQDTATPGGVA 243 T +D GLA S Y + + A +G YR++ QA ++ +R ++ A GVA Sbjct: 380 TRVDKGLASSAALNSLFQPYGVGKVNFTAGVGGYRSS-QALAIGSGYRVNENVALKAGVA 438 Query: 244 RLSGANPYWRVAYNQEW 260 ++ + ++N EW Sbjct: 439 YAGSSDVMYNASFNIEW 455
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 34.8 bits (80), Expect = 6e-04 Identities = 57/354 (16%), Positives = 112/354 (31%), Gaps = 17/354 (4%) Query: 31 AFILVASEFMPVSLLTPIAGSL----HLTEGQAGQAISVSGAFALLTSLFIP---AMAAR 83 VA + + + L+ P+ L + + +AL+ P A++ R Sbjct: 10 ILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDR 69 Query: 84 LDRKVLLLLLTLLTVVSGVVVTLAPDYSTFIIGRALIGVAIGGFWSMSAATAMRLVPHHD 143 R+ +LL+ V ++ AP IGR + G+ G +++ A + + Sbjct: 70 FGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGIT-GATGAVAGAYIADITDGDE 128 Query: 144 VPHALAIVNGGNALATVLAAPLGSLLGAVVGWRGAFFCIVPVATIALVWQWMTLPALKAD 203 ++ V LG L+G FF + + + LP Sbjct: 129 RARHFGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFAAAALNGLNFLTGCFLLPESHKG 187 Query: 204 SSPGAAGDVFTLLRRPAVALGMAAVGLFFMGQFMLF-------TYLRPFLETVTNTRAST 256 + L A GM V F++ F E + A+T Sbjct: 188 ERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATT 247 Query: 257 LSFVLLVIGVAGFVGTAVI-GTFLKDGLYRTLIVIPVLMAGIALALASFGGSLAASTILL 315 + L G+ + A+I G R +++ ++ G L +F + ++ Sbjct: 248 IGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIM 307 Query: 316 AIWGLVATAAPVGWWTWLARTLPQDAETGGGLMVAIIQLAITLGAAGGGAMFDA 369 + P + + G + A+ L +G A++ A Sbjct: 308 VLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAA 361
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 27.3 bits (60), Expect = 0.047 Identities = 18/97 (18%), Positives = 42/97 (43%), Gaps = 1/97 (1%) Query: 78 PGKELLERTSMNSWDDQKVRDVLARNGRKKVVVSGLWTEVCNTTFALCAMAEGGYEIYMV 137 +L + +++ + +++ + GR +++++G++ + A A E + + V Sbjct: 116 DDDLVLTKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMED-IKAFFV 174 Query: 138 ADASGGTSKEAHDYAMQRLIQAGAVPVTWQQVLLEWQ 174 DA S E H A++ A V +L + Q Sbjct: 175 GDAVADFSLEKHQMALEYAAGRCAFTVMTDSLLDQLQ 211
>PF04647#Accessory gene regulator B Length = 212 Score = 29.4 bits (66), Expect = 0.011 Identities = 14/64 (21%), Positives = 23/64 (35%), Gaps = 3/64 (4%) Query: 169 VDEMGYLPMDREQANLLFQVIAKRYETGSLVLTSNLPFGQWDQTFAGDATLTAALLDRLL 228 VD Y P ++E+ +V ++L G + L+AA+ R Sbjct: 13 VDRSDY-PFNQEEIRYGIEVFLGTVFQIIIILLVAFVIGLAKEVAF--CLLSAAVYRRFS 69 Query: 229 HHAH 232 AH Sbjct: 70 GGAH 73
>PF06580#Sensor histidine kinase Length = 349 Score = 33.7 bits (77), Expect = 0.001 Identities = 17/91 (18%), Positives = 35/91 (38%), Gaps = 11/91 (12%) Query: 360 IVQESLTNASKYAHATIVS---VALDASEEG--VRLRVRDNGRGFPADLERRRMVGHHGL 414 +VQ + N K+ A + + L +++ V L V + G L+ + GL Sbjct: 259 LVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLA---LKNTKESTGTGL 315 Query: 415 LGMEQRAIALGG---TLTIDSTPGGGVTIIV 442 + +R L G + + G +++ Sbjct: 316 QNVRERLQMLYGTEAQIKLSEKQGKVNAMVL 346
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 52.5 bits (126), Expect = 6e-11 Identities = 26/127 (20%), Positives = 50/127 (39%), Gaps = 3/127 (2%) Query: 14 RVLLIEDSPVLRGMVLEYLKASAFVAVVEWADTEDLALRLLAQGHYDVVIVDLQLRQGNG 73 +L+ +D +R VL + A V ++ R +A G D+V+ D+ + N Sbjct: 5 TILVADDDAAIR-TVLNQALSRAGYDVRITSNAAT-LWRWIAAGDGDLVVTDVVMPDENA 62 Query: 74 FKVLQSLRDQASPSVRIVYTNHAQVPTYRQRCFEAGANYFFDKSLELDKVFEVIEERAGM 133 F +L ++ +V + T + E GA + K +L ++ +I Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTA-IKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 134 VRPRPQA 140 + RP Sbjct: 122 PKRRPSK 128
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 91.0 bits (226), Expect = 1e-23 Identities = 37/122 (30%), Positives = 54/122 (44%), Gaps = 2/122 (1%) Query: 2 IRVLIADDHEIVRAGLRQFLSEERDIEVAGEAASGEEVMEQLRTGTFDVVVLDISMPDRN 61 +L+ADD +R L Q L +V ++ + + G D+VV D+ MPD N Sbjct: 4 ATILVADDDAAIRTVLNQAL-SRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 62 GIDTLKLVRQRHPDLPVLILSTFPEDQYAINLIRAGASGYLTKESAPDELVKAIRTVSQG 121 D L +++ PDLPVL++S AI GA YL K EL+ I Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 122 RR 123 + Sbjct: 122 PK 123
>YERSINIAYOPE#Yersinia virulence determinant YopE protein signature. Length = 219 Score = 28.2 bits (62), Expect = 0.045 Identities = 24/119 (20%), Positives = 43/119 (36%), Gaps = 3/119 (2%) Query: 215 SGTVTDASGRILSGQTVEAFWNSL--RHAKPITFGLNCALGAALMRPYIAELAKICDTAV 272 S +V + SGR +S QT + + N+L R P L + L + + I Sbjct: 20 SSSVGEMSGRSVSQQTSDQYANNLAGRTESPQGSSLASRIIERLSSVAHSVIGFI-QRMF 78 Query: 273 SCYPNAGLPNPMSDTGFDETPEVTSSLVDEFAAAGLVNLVGGCCGTTPEHIRAIAERVA 331 S + + P +P S + + AA L + E ++ ++ A Sbjct: 79 SEGSHKPVVTPAPTPAQMPSPTSFSDSIKQLAAETLPKYMQQLNSLDAEMLQKNHDQFA 137
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 40.4 bits (94), Expect = 5e-06 Identities = 30/141 (21%), Positives = 44/141 (31%), Gaps = 13/141 (9%) Query: 22 RWRRWGVVALAALLAHGIAVIWVARSHQVMWPPAPEQ------VVPTLLLQP-------E 68 R W + + +A + HQV+ PAP Q V P L P E Sbjct: 7 RRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVTPADLEPPQAVQPPPE 66 Query: 69 PVHPPAPPAPAPVAAKPRPPAPRPHPQHAPTPTPEPAPTVPDMADTELPELTGTGAQASA 128 PV P P P P+ P P P+P V + ++ + A Sbjct: 67 PVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESRPASPFE 126 Query: 129 DTGVVTDLGAERPDAPAAPPG 149 +T + A + P Sbjct: 127 NTAPARLTSSTATAATSKPVT 147 Score = 35.3 bits (81), Expect = 2e-04 Identities = 23/107 (21%), Positives = 37/107 (34%), Gaps = 3/107 (2%) Query: 53 PPAPEQVVPTLLLQPEPVHPPAPPAPAPVAA-KPRP-PAPRPHPQHAPTPTPEPAPTVPD 110 PP Q P +++PEP P P P +P P P+P P+ +P V Sbjct: 57 PPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKP 116 Query: 111 MADTELPELTGTGAQASADTGVVTDLGAERPDAPAAPPGPGFALPPS 157 ++ A A + T ++ + A+ P P Sbjct: 117 -VESRPASPFENTAPARLTSSTATAATSKPVTSVASGPRALSRNQPQ 162 Score = 30.3 bits (68), Expect = 0.009 Identities = 22/112 (19%), Positives = 32/112 (28%), Gaps = 5/112 (4%) Query: 44 VARSHQVMWPPAPEQVVPTLLLQPEPVHPPAPPAPAPVAAKPRPPAPR-PHPQHAPTPTP 102 V + + P PE + PV P KP P P + Sbjct: 61 VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESR 120 Query: 103 EPAPTVPDMADTELPELTGTGAQASADTGVVTDLGAERPDAPAAPPGPGFAL 154 +P +T LT + A A+ V + R + P P A Sbjct: 121 PASP----FENTAPARLTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQ 168
>PF03309#Bvg accessory factor Length = 271 Score = 136 bits (343), Expect = 1e-40 Identities = 55/280 (19%), Positives = 100/280 (35%), Gaps = 34/280 (12%) Query: 13 LLLIDAGNTRIKWAWTAADVAPPAVAPGGTPWQ--HAGARPHDQLAELVEDWRDCHAGAG 70 LL ID NT + V W+ D+LA + G Sbjct: 2 LLAIDVRNTHTVVGLISGSGDHAKVVQ---QWRIRTEPEVTADELALTI------DGLIG 52 Query: 71 MAPPDV----WISVVAGPALRDALCARIARVFDGARLRIVASEAAAAGLRNGYRDPAQLG 126 + +S V P++ + + + + ++ G+ +P ++G Sbjct: 53 DDAERLTGASGLSTV--PSVLHEVRVMLEQYW-PNVPHVLIEPGVRTGIPLLVDNPKEVG 109 Query: 127 TDRWVGAVGARHAWPDTALLLVTAGTATTLDIVAPDGRFAGGLILPGLTLMMRALSRNTA 186 DR V + A H + A ++V G++ +D+V+ G F GG I PG+ + A + +A Sbjct: 110 ADRIVNCLAAYHKYGT-AAIVVDFGSSICVDVVSAKGEFLGGAIAPGVQVSSDAAAARSA 168 Query: 187 QLPEIDIGYLAARDDAQAPADVPSWADNTQDAIALGCVTAQAGAI----AQTWQALQAQY 242 L +++ P V NT + + G V AG + + + Sbjct: 169 ALRRVELT---------RPRSV--IGKNTVECMQAGAVFGFAGLVDGLVNRIRDDVDGFS 217 Query: 243 PGPYRCVLSGGARAALAPHLRMPFQMHDNLVLLGLQVLAH 282 V +G + P LR +L L GL+++ Sbjct: 218 GADVAVVATGHTAPLVLPDLRTVEHYDRHLTLDGLRLVFE 257
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 27.0 bits (60), Expect = 0.018 Identities = 8/36 (22%), Positives = 17/36 (47%) Query: 12 SLLQIMLRGLPILLMAVVCGVTFLLVQVNTPQTEET 47 +L +++ ++A + G+ L Q T E+T Sbjct: 11 ALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQT 46
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 34.8 bits (80), Expect = 0.002 Identities = 30/189 (15%), Positives = 74/189 (39%), Gaps = 14/189 (7%) Query: 637 QVRAAVE--RAGVPDALFIDMKAEADRLYVNYVREDIRLSLAGVGAIALLLAIALRSARR 694 ++A + + P + + + + E ++ + + L++ + L++ R Sbjct: 305 AIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMRA 364 Query: 695 AM-----LALAPLAAAVLMVAAGFALAGVPLTILHL-IGMLL---IVAVGSNYALFFSRR 745 + + + L ++ A G+++ + + + L IG+L+ IV V + + + Sbjct: 365 TLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMMEDK 424 Query: 746 ANASAGAQPVTPQTLVSLLIANLATVAGFGLLAL---SRVPMLETFGLTVGPGAILALVF 802 + Q +L+ + A F +A S + F +T+ L+++ Sbjct: 425 LPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLV 484 Query: 803 AAILAPAAT 811 A IL PA Sbjct: 485 ALILTPALC 493
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 99.7 bits (248), Expect = 2e-27 Identities = 70/247 (28%), Positives = 112/247 (45%), Gaps = 14/247 (5%) Query: 3 ALVTGGSGAIGQAVSEALARAGHEVWVHANRNLEQAEAVAQRIVAAGGTAHAIAFDVTDA 62 A +TG + IG+AV+ LA G + + N E+ E V + A A A DV D+ Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHI-AAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDS 69 Query: 63 QATEAALAPVL-DGAPVQILVNNAGVHDDAPMAGMTQQQWRRVIDVSLNGFFNVTQPLLM 121 A + A + + P+ ILVN AGV + ++ ++W V+ G FN ++ + Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSK 129 Query: 122 PMIRTRWGRIINMASVAGVMGNRGQANYAAAKAGLIGATKSLAQELASRGITVNAVAPGI 181 M+ R G I+ + S + A YA++KA + TK L ELA I N V+PG Sbjct: 130 YMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGS 189 Query: 182 IASPMAGEAFP------------AERIKQLVPAGRAGQPDEVAGMVAYLASDAAAYVTGQ 229 + M + E K +P + +P ++A V +L S A ++T Sbjct: 190 TETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITMH 249 Query: 230 VLSINGG 236 L ++GG Sbjct: 250 NLCVDGG 256
>DNABINDNGFIS#DNA-binding protein FIS signature. Length = 98 Score = 74.2 bits (182), Expect = 2e-21 Identities = 29/75 (38%), Positives = 55/75 (73%) Query: 2 SRNPIERCIRDSLDTYYRDLDGENPSNVYDMVLQAIERPLLETVMEWASNNQSLAADYLG 61 ++ P+ ++ +L Y+ L+G++ +++Y++VL +E+PLL+ VM++ NQ+ AA +G Sbjct: 23 TQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMG 82 Query: 62 INRNTLRKKLQQHGL 76 INR TLRKKL+++G+ Sbjct: 83 INRGTLRKKLKKYGM 97
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 87.0 bits (215), Expect = 2e-21 Identities = 64/255 (25%), Positives = 112/255 (43%), Gaps = 14/255 (5%) Query: 229 LAGRTALVTGASRGIGAAIAQVLARDGARVLCLD-VPAAQPALDGVARAIG--GEALAYD 285 + G+ A +TGA++GIG A+A+ LA GA + +D P + +A EA D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 286 IAEAETPARLARQLAA-MGGIDILVHNAGITRDKTIARMTEAAWRSVLDINLAAQLRIND 344 + ++ + ++ MG IDILV+ AG+ R I +++ W + +N + Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 345 ALLAAGALHAGGAIVCVSSISGIAGNPGQTNYATAKAGVIGLVQACAPLLAERGITINAV 404 ++ G+IV V S YA++KA + + LAE I N V Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 405 APGFIETQMTAAVPFTIREAGRRMNAMAQG----------GQPVDVAEAIAWLACPASNG 454 +PG ET M ++ A + + + +P D+A+A+ +L + Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGH 245 Query: 455 VTGNVVRVCGQSLLG 469 +T + + V G + LG Sbjct: 246 ITMHNLCVDGGATLG 260
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 60.8 bits (147), Expect = 5e-13 Identities = 24/104 (23%), Positives = 35/104 (33%), Gaps = 5/104 (4%) Query: 1 MARPGAG---DTKNRILEATELLFIEFGYEAMSLRQITARAKVNLAAVNYHFGSKEALMQ 57 MAR +T+ IL+ LF + G + SL +I A V A+ +HF K L Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 58 SVLGRRLDPLNTRRLALLTACEE--RWPQRLSCEHVLGALFVPA 99 + + L R HVL + Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEE 104
>SECA#SecA protein signature. Length = 901 Score = 29.8 bits (67), Expect = 0.033 Identities = 19/65 (29%), Positives = 33/65 (50%), Gaps = 4/65 (6%) Query: 253 VLVFTRTKHGANRLAEQLTRDGIPALAIHG-NKSQSARTRALSEFKAGTLRVLVATDIAA 311 VLV T + + ++ +LT+ GI ++ + A A + + A V +AT++A Sbjct: 452 VLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAA---VTIATNMAG 508 Query: 312 RGIDI 316 RG DI Sbjct: 509 RGTDI 513
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 92.6 bits (230), Expect = 6e-24 Identities = 42/157 (26%), Positives = 79/157 (50%), Gaps = 5/157 (3%) Query: 2 RILIAEDDATLADGLTRSLRQAGYAVDRAADGAAADAALSAQTAQTYDLLILDVGLPRLS 61 IL+A+DDA + L ++L +AGY V ++ A ++A DL++ DV +P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGD---GDLVVTDVVMPDEN 61 Query: 62 GLEVLKRLRSRGAMLPVLILTAADSVDERVKGLDLGADDYMAKPFALSELEARVRALVRR 121 ++L R++ LPVL+++A ++ +K + GA DY+ KPF L+EL + + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 122 GTGGGATLVRHGPLAFDQVGRIAYIRD--QMVDLSAR 156 + L VGR A +++ +++ + Sbjct: 122 PKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQ 158
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 62.0 bits (150), Expect = 6e-14 Identities = 28/160 (17%), Positives = 56/160 (35%), Gaps = 2/160 (1%) Query: 30 RERKRRDTLQRIAQTGLDLFIAKGYEATTLDDVAAAAGISRRTFFHYFTSKDEILLAWQV 89 +++ ++T Q I L LF +G +T+L ++A AAG++R + +F K ++ Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 90 GLVDALYDAVLQAATDQ--SPLEALCGALQKLASHFDAEKAIDIARVLRSSEQLRAANHA 147 + + L+ PL L L + E+ + + + A Sbjct: 65 LSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMA 124 Query: 148 KFMNLENAAFEALCRLWPQRGRRGLLRMVAMAGLGAFRVA 187 + Q + + + A L R A Sbjct: 125 VVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAA 164
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 49.4 bits (118), Expect = 1e-08 Identities = 57/239 (23%), Positives = 89/239 (37%), Gaps = 61/239 (25%) Query: 1 MMSNACGVDFGTSNSTVGWLRSDAPTLLPLEDGKVT-LPSVIFFHAEDPLVSYGRAALTD 59 M SN +D GT+N+ + G V PSV+ + + Sbjct: 8 MFSNDLSIDLGTANTLI----------YVKGQGIVLNEPSVV------AIRQDRAGSPKS 51 Query: 60 YLA-GYEGRLM-----------RSLKSLLGTSMMDESTEVMGQAMPFRKLLAHFIGELKR 107 A G++ + M R +K G TE M L HFI K+ Sbjct: 52 VAAVGHDAKQMLGRTPGNIAAIRPMKD--GVIADFFVTEKM---------LQHFI---KQ 97 Query: 108 RAERAAGHEFRRAVLGRPVFFIDEDPKADQLAEDTLSEIARDAGFDEIAFQYEPIAAAFD 167 + R ++ PV A Q+ + E A+ AG E+ EP+AAA Sbjct: 98 VHSNSFMRPSPRVLVCVPV-------GATQVERRAIRESAQGAGAREVFLIEEPMAAAIG 150 Query: 168 YEAGISGEELVLVADIGGGTSDFSLVRLSPDRAKRPDRREDILANGGVHIGGTDFDRAL 226 +S +V DIGGGT++ +++ L+ ++ + V IGG FD A+ Sbjct: 151 AGLPVSEATGSMVVDIGGGTTEVAVISLN-----------GVVYSSSVRIGGDRFDEAI 198
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 37.1 bits (86), Expect = 1e-04 Identities = 25/123 (20%), Positives = 44/123 (35%), Gaps = 7/123 (5%) Query: 2 AKIAVVSADESHLQFLAGLVTQAA--NHVVQRARTTPSQALAQPGLTLGTDLLVLEAGNF 59 A I V D + L +++A + A T A G DL+V + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDG-----DLVVTDVVMP 58 Query: 60 TADDIDQLRRLTAEQQDTLCMLLTENPSAELLMRAMRAGVQCVLPWPPDAQEFRDEVQRC 119 + D L R+ + D ++++ + ++A G LP P D E + R Sbjct: 59 DENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 120 TSH 122 + Sbjct: 119 LAE 121
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 125 bits (315), Expect = 3e-32 Identities = 55/268 (20%), Positives = 113/268 (42%), Gaps = 29/268 (10%) Query: 260 RIINMMSVEAPQQVMLEVKVAEVSKTLINQMGAA---------------LNLNGSF-GSW 303 R+I + + QV++E +AEV +G L ++ + G+ Sbjct: 335 RVIAQLDIR-RPQVLVEAIIAEVQDADGLNLGIQWANKNAGMTQFTNSGLPISTAIAGAN 393 Query: 304 TFGALANFLSGAPDIFSADKANKLPF-----QLRVDAQKGDGLVKVLAEPNLMAISGQEA 358 + S S+ F + + A +LA P+++ + EA Sbjct: 394 QYNKDGTVSSSLASALSSFNGIAAGFYQGNWAMLLTALSSSTKNDILATPSIVTLDNMEA 453 Query: 359 SFLAGGKVYIPVPQSFGTGTT-TILLQEETFGVGLRFTPTVLENGRINLKVAPEVSELSP 417 +F G +V + +G ++ +T G+ L+ P + E + L++ EVS ++ Sbjct: 454 TFNVGQEVPVLTGSQTTSGDNIFNTVERKTVGIKLKVKPQINEGDSVLLEIEQEVSSVAD 513 Query: 418 TGVAVTAPNVSGTSILPLITTRRASTTLQVHDGQSFAIGGLIKSNVTGSLKAIPGVGELP 477 + + + TR + + V G++ +GGL+ +V+ + +P +G++P Sbjct: 514 AAS------STSSDLGATFNTRTVNNAVLVGSGETVVVGGLLDKSVSDTADKVPLLGDIP 567 Query: 478 VIGALARSTSFQQDQTELLFVVTPHLVK 505 VIGAL RSTS + + L+ + P +++ Sbjct: 568 VIGALFRSTSKKVSKRNLMLFIRPTVIR 595
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 28.7 bits (64), Expect = 0.009 Identities = 11/31 (35%), Positives = 17/31 (54%) Query: 1 MTRVAWQAGVTLAELTMVLAILAILAVFAMP 31 M Q G TL E+ +V+ I+ +LA +P Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVP 31
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 40.6 bits (95), Expect = 3e-07 Identities = 19/88 (21%), Positives = 32/88 (36%), Gaps = 2/88 (2%) Query: 1 MLRPTGFTFIELLITLAIAGVLA-LAASQAWSGAYLRTERMAAHAALVATMAALEQHHAQ 59 + GFT +E+++ + I GVLA L + ++ A + +VA AL+ + Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKE-KADKQKAVSDIVALENALDMYKLD 62 Query: 60 TGSYALPGDDTSPLDRWPHTLEHPRGYR 87 Y L P Y Sbjct: 63 NHHYPTTNQGLESLVEAPTLPPLAANYN 90
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 29.5 bits (66), Expect = 0.006 Identities = 10/25 (40%), Positives = 15/25 (60%) Query: 3 MRPLRPSRGFMLVFVMTSTVLLGLL 27 MR RGF L+ +M V++G+L Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGVL 25
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 39.9 bits (93), Expect = 1e-06 Identities = 19/58 (32%), Positives = 31/58 (53%), Gaps = 3/58 (5%) Query: 9 RRRSARGFTLLELMVTIAIISIMLVLVAPSF---SDFLRKQRLLSAADSVASAIGQAR 63 RGFTLLE+MV I II ++ LV P+ + KQ+ +S ++ +A+ + Sbjct: 3 ATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK 60
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 47.2 bits (112), Expect = 2e-09 Identities = 13/43 (30%), Positives = 31/43 (72%) Query: 12 QRGFTLIELMIVVIVVAILSTIAYPSYTQFVQKSRRTQAKAAL 54 QRGFTL+E+M+V++++ +L+++ P+ +K+ + +A + + Sbjct: 7 QRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDI 49
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 32.9 bits (75), Expect = 6e-04 Identities = 15/33 (45%), Positives = 22/33 (66%), Gaps = 1/33 (3%) Query: 10 RRTRGFSLVELMVALVIALLVLAATVSFYLMTR 42 + RGF+L+E+MV +VI + VLA+ V LM Sbjct: 5 DKQRGFTLLEIMVVIVI-IGVLASLVVPNLMGN 36
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 77.6 bits (191), Expect = 7e-20 Identities = 32/135 (23%), Positives = 58/135 (42%), Gaps = 9/135 (6%) Query: 1 MDKSQYRFLVVDDFPTMRRIIRGQLKELGFANIDEAEDGTAGLSKIKESRFDFVISDWNM 60 M + LV DD +R ++ L G+ ++ + I D V++D M Sbjct: 1 MTGA--TILVADDDAAIRTVLNQALSRAGY-DVRITSNAATLWRWIAAGDGDLVVTDVVM 57 Query: 61 PKMDGLQMLQAIRA-DPNPGISKLPVLIVTAEAKKENVIAAAQAGASGYVVKPFTAATLG 119 P + +L I+ P+ LPVL+++A+ I A++ GA Y+ KPF L Sbjct: 58 PDENAFDLLPRIKKARPD-----LPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELI 112 Query: 120 EKLNKIFEKFERAEA 134 + + + +R + Sbjct: 113 GIIGRALAEPKRRPS 127
>PF07520#Virulence protein SrfB Length = 1041 Score = 29.2 bits (65), Expect = 0.037 Identities = 12/31 (38%), Positives = 15/31 (48%) Query: 310 LSSGERRISGVMIESHLEEGRQDLKPGVPLQ 340 L G R G++IE E R DL PL+ Sbjct: 283 LDIGNSRTCGILIERFPGETRVDLTRSFPLE 313
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 63.5 bits (154), Expect = 2e-14 Identities = 39/209 (18%), Positives = 76/209 (36%), Gaps = 16/209 (7%) Query: 19 PTQERSRATVDAIMQAATYILVKFGWERLTTNAIAERAGVNIGSLYQYFPNKQAIIAELQ 78 T++ ++ T I+ A + + G + IA+ AGV G++Y +F +K + +E+ Sbjct: 4 KTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIW 63 Query: 79 RRHVLQTREILSKALPQVSEQ--RSLREALTLLV-----------VAMIDEHRVAPAVHR 125 E+ + + LRE L ++ + I H+ Sbjct: 64 ELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEM 123 Query: 126 AIDAELPRSVRVPLGDESRGGDQPLQVLQPFMKNVPDPHFALRIARIAAHAVIHEAASHQ 185 A+ + R++ + D + + ++ A I R ++ Sbjct: 124 AVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADL-MTRRAAIIMRGYISGLMENWLF-A 181 Query: 186 PELFDRPDFVDEVVA-LLEGYFRRPAARS 213 P+ FD + VA LLE Y P R+ Sbjct: 182 PQSFDLKKEARDYVAILLEMYLLCPTLRN 210
>SECA#SecA protein signature. Length = 901 Score = 56.4 bits (136), Expect = 4e-10 Identities = 19/23 (82%), Positives = 22/23 (95%) Query: 847 RKIGRNEPCPCGSGAKYKRCHGR 869 RK+GRN+PCPCGSG KYK+CHGR Sbjct: 877 RKVGRNDPCPCGSGKKYKQCHGR 899
>PF05272#Virulence-associated E family protein Length = 892 Score = 49.3 bits (117), Expect = 5e-08 Identities = 95/361 (26%), Positives = 139/361 (38%), Gaps = 94/361 (26%) Query: 31 LLDRLDSVLAILFPAGKKRRNKFVIGDIQGNLGDSLEIVLDGEKAGLWTDRATGDGG--- 87 LL R +L P G +++ G + G GDS ++ + G W D +TG+ G Sbjct: 18 LLTRAKDLLPEWLPGGVLVGHEYECGSLAGGKGDSCKVNV---TTGKWCDFSTGESGRDL 74 Query: 88 -DVFAVIAGTLGVDVQTEFPR---VLARAADLLGLASTQPVRRK-RKEPPTDDL------ 136 D++A I G + R + + A ++G + P + R EPP + Sbjct: 75 LDLYAEIHGLKVSKAAAQVAREEGLESVAGIVMGAPAGAPAPKPPRPEPPPRPVVEKECW 134 Query: 137 ------------------GPETAKWDYLDAAGR------LIGVVYRYDPPGRGKEFRPWD 172 P+ + D ++ R L G V R+ K P+ Sbjct: 135 ETIQPVPEHAVPPSFWHPAPKGREPDKIEHTARYQVGPVLWGYVVRFIKSDGDKLTLPYV 194 Query: 173 AKRRKMAPP---------DPRPLYNQPGLASATQ-VVLVEGEK---CAQALIDAG---IV 216 R + DPRPLY A ++ VVLVEGE+ C Q L+DAG + Sbjct: 195 YSRSQRDGSEAWKWRGWDDPRPLYFPSHRAPESRTVVLVEGERKADCLQQLLDAGAPGVY 254 Query: 217 ATTAMHGANAPVEKTDWSPLAGKAVLIWPDRD--------------------------KP 250 + G + K DWS LAG V++WPD D KP Sbjct: 255 CVASWPGGSNGWPKADWSWLAGCTVVLWPDCDSLREKLTRQELKDTPDPLAREKLLAAKP 314 Query: 251 GWEYADRASQ-AILQAGALL------VAILLP---PDDKPEGWDAADAIE-EGFDVAGYL 299 + + Q A+L G +L +LP P KP GWD DAIE +G+D+ L Sbjct: 315 YLPFDKQPGQKAMLGIGEVLRDTHGCTVQMLPIDKPGIKPSGWDCRDAIETDGWDIDRVL 374 Query: 300 A 300 A Sbjct: 375 A 375
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 28.2 bits (62), Expect = 0.005 Identities = 9/26 (34%), Positives = 14/26 (53%) Query: 21 VWRPSDGGPPRTNMVGFAAPDETLLD 46 W P D PP+ V P+ET+++ Sbjct: 9 TWTPDDLAPPQAEFVPIVEPEETIIE 34
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 26.0 bits (57), Expect = 0.032 Identities = 11/50 (22%), Positives = 21/50 (42%), Gaps = 4/50 (8%) Query: 5 KDLLSQKAKLEEQLEAAR---QKELAEITAQV-RQVVQEYGLTAEDIGLA 50 LL A+ L + R ++ A+ +V ++ Q G++ DI Sbjct: 699 NQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQT 748
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 48.9 bits (116), Expect = 1e-07 Identities = 63/419 (15%), Positives = 136/419 (32%), Gaps = 32/419 (7%) Query: 498 GEVEQAVSKASSTVNDATARMAEAYKGLTSIIDGHLQRQVEAVKARYQQELSALERSGQA 557 G V ++ T + + + + +++ AL+ Sbjct: 32 GLVVNTNEVSAVATRSQTDTLEKVQERADKFEIENNTLKLKNSD--LSFNNKALKDHNDE 89 Query: 558 QAVQIATSTQLLVGALTQQTALRQQAATEALKLIDDESRARVDAVAREGKTEAERAANVQ 617 +++ +L ++A+ + A T Sbjct: 90 LTEELS---NAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTL 146 Query: 618 RVENEILATRRQTLTQAASEYRQHIDALNAEANRHLTEIRRIEDEKRQLSMSTEERIRDI 677 E LA R+ L +A A +A+ E +E + +L + E Sbjct: 147 EAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGA---- 202 Query: 678 RRAGLSDYEAQEDRKRQIAEYQASARAALADGEFDQARQRASKAMDLAAQVASAQSGEAK 737 ++ A + + + +A+ A AD E + ++ Sbjct: 203 ----MNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMN------------FSTADSA 246 Query: 738 RAEDARKQSEAAVTQVAQLEAQAREATGRREYAQAEALTRQADELRARSAQQAANADAQA 797 + + + A + A+LE A A+ T +A++ + + +Q Sbjct: 247 KIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQV 306 Query: 798 VRGKAAVNEAIGRIRDSQAILNQTLDAEAQAHQRAAQSAVSARQDIQQTLAQTDSQIAQL 857 A +++ R D+ + L+AE Q + + + ++RQ +++ L + QL Sbjct: 307 ---LNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQL 363 Query: 858 TAKLQQGLKVTIDADTQRFDKAIADLDKALVERERLVVIKADLEQAEKTLQDYEQRLKE 916 A+ Q+ + ++ R DLD + RE ++ LE+A L E+ KE Sbjct: 364 EAEHQKLEEQNKISEASRQS-LRRDLDAS---REAKKQVEKALEEANSKLAALEKLNKE 418
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 36.6 bits (84), Expect = 3e-04 Identities = 10/78 (12%), Positives = 24/78 (30%) Query: 30 TPPTQSAATATANTEQEQRLRQQQQAREREQAVQAPAVRAQQAAPAEFPELPTETPCFRI 89 PP + + T T E ++ + + EQ + ++ A + T + Sbjct: 1026 PPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEV 1085 Query: 90 DRFALEVPQDLPEAARTK 107 + E + + Sbjct: 1086 AQSGSETKETQTTETKET 1103
>PERTACTIN#Pertactin signature. Length = 922 Score = 31.6 bits (71), Expect = 0.026 Identities = 45/155 (29%), Positives = 57/155 (36%), Gaps = 19/155 (12%) Query: 368 APDGSINFAQLGGKPAPEAKPAA-PAPAAQPKPLDVAVGKLQLANSSVHWRDATTQPAAD 426 A +G+ ++ +G K P KPA P P P+P R Sbjct: 553 AANGNGQWSLVGAKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQP 612 Query: 427 LVLDDLHG--DAAVRTLGGPTTLDVGAKLASGGTLNVKGSTSLEKRTGELELKLEALKLA 484 +L +AAV T G + TL S +L KR GEL L +A Sbjct: 613 PAGRELSAAANAAVNTGG----------VGLASTLWYAESNALSKRLGELRLNPDAGGAW 662 Query: 485 GIGPYLRQAGAPQLQNGALSA-DGKIA-LEFGADK 517 G G RQ QL N A D K+A E GAD Sbjct: 663 GRGFAQRQ----QLDNRAGRRFDQKVAGFELGADH 693
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 135 bits (340), Expect = 2e-40 Identities = 63/147 (42%), Positives = 87/147 (59%), Gaps = 5/147 (3%) Query: 73 APAAAPQAQPTPAAKPVVGSEKVTFAADALFDFDKAVLKPEGKSKLDDLVSKLKGITLE- 131 AAP P PA P V ++ T +D LF+F+KA LKPEG++ LD L S+L + + Sbjct: 193 QGEAAPVVAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKD 252 Query: 132 -VVIAVGHTDSFGSDKYNDRLSVRRAEAVKGYLVSKGIEANRVYTEGKGKRQLKVDPKSC 190 V+ +G+TD GSD YN LS RRA++V YL+SKGI A+++ G G+ V +C Sbjct: 253 GSVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPADKISARGMGESN-PVTGNTC 311 Query: 191 KG--ARKAQIACQQPNRRVEVEVVGTR 215 R A I C P+RRVE+EV G + Sbjct: 312 DNVKQRAALIDCLAPDRRVEIEVKGIK 338
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 125 bits (316), Expect = 3e-37 Identities = 81/257 (31%), Positives = 125/257 (48%), Gaps = 10/257 (3%) Query: 3 QALNNQVALVTGASRGIGRAIALELARQGATVVGTATSEAGAQAISAYFAEAGVKGAGVV 62 + + ++A +TGA++GIG A+A LA QGA + + + + + Sbjct: 4 KGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP 63 Query: 63 LNVNDAARCEAVIDEAIKTHGGLNILVNNAGITQDNLAMRMKDDEWMAVIDTNLSAVFRL 122 +V D+A + + + G ++ILVN AG+ + L + D+EW A N + VF Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 123 SRAVLRPMMKARGGRIINITSVVGSAGNPGQANYAAAKAGVEGMARAMAKEIGSRNITVN 182 SR+V + MM R G I+ + S A YA++KA + + E+ NI N Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 183 SVAPGFIDTDMTKVLSDEQHTA----------LKAQIPLGRLGMPEDIANAVAFLASPAA 232 V+PG +TDM L +++ A K IPL +L P DIA+AV FL S A Sbjct: 184 IVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 233 GYITGATLHVNGGMYMG 249 G+IT L V+GG +G Sbjct: 244 GHITMHNLCVDGGATLG 260
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 78.9 bits (194), Expect = 4e-18 Identities = 36/157 (22%), Positives = 62/157 (39%), Gaps = 24/157 (15%) Query: 114 SRGVGSGFIMSGDGYVLTNAHVVEGAETIYVTLTDKR-----------EFKA-KLIGSDK 161 + SG ++ G +LTN HVV+ L F A ++ Sbjct: 100 GTFIASGVVV-GKDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSG 158 Query: 162 RTDVALVKVEAT--------GLPSLKLGDSDKVRVGEWVLAIGSPFGLDNTVTAGIVSAK 213 D+A+VK + + ++ + +V + + G P A + +K Sbjct: 159 EGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKPV---ATMWESK 215 Query: 214 GRDTGDYLPFIQSDVAVNPGNSGGPLINLRGEVIGIN 250 G+ T +Q D++ GNSG P+ N + EVIGI+ Sbjct: 216 GKITYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIH 252
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 138 bits (350), Expect = 8e-37 Identities = 107/497 (21%), Positives = 200/497 (40%), Gaps = 99/497 (19%) Query: 3 NIRNFSIIAHIDHGKSTLADRIIQLCGG---LSDREMEAQVLDSMDIEKERGITIKAQTA 59 I N ++AH+D GK+TL + ++ G L + D+ +E++RGITI QT Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITI--QTG 59 Query: 60 ALSYKARDGKVYNLNLIDTPGHVDFSYEVSRSLSACEGALLVVDASQGVEAQTVANCYTA 119 S++ + KV N+IDTPGH+DF EV RSLS +GA+L++ A GV+AQT + Sbjct: 60 ITSFQWENTKV---NIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHAL 116 Query: 120 IELGVEVVPVLNKIDLPAADPDSAIQEIEDVIGIDA--------------QDATRCSAKT 165 ++G+ + +NKID D + Q+I++ + + + T Sbjct: 117 RKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWD 176 Query: 166 GV--GVPDVLEALIAKVPAPKGDPDAPLQALIID---------SWFDNYVGVVMLVRVVN 214 V G D+LE ++ + + + S +N +G+ L+ V+ Sbjct: 177 TVIEGNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNN-IGIDNLIEVIT 235 Query: 215 GTL-------------------------------------RAKDKVLLMATGAQHLVEQV 237 +D V + + E Sbjct: 236 NKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKIKITEMY 295 Query: 238 GVFSPKSVPRESLSAGQVGFVIAGIKELKAAKVGDTITHVVPRKADAPLPGFKEVKPQVF 297 + + + +G++ + +L + +GDT + + PLP + Sbjct: 296 TSINGELCKIDKAYSGEIVILQNEFLKLNSV-LGDTKLLPQRERIENPLPLLQTT----- 349 Query: 298 AGLYPVEANQYEALRESLEKLQLNDASLQFE-PEVSQALGFGFRCGFLGLLHMEIVQERL 356 + P + Q E L ++L ++ +D L++ + + FLG + ME+ L Sbjct: 350 --VEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIIL----SFLGKVQMEVTCALL 403 Query: 357 EREFDMDLITTAPTVVYQVMQR----DGTTVQVENPAK--------MPDPSKIESILEPI 404 + ++ +++ PTV+Y M+R T+ +E P P + S ++ Sbjct: 404 QEKYHVEIEIKEPTVIY--MERPLKKAEYTIHIEVPPNPFWASIGLSVSPLPLGSGMQYE 461 Query: 405 VTVNL-YMPQEYVGAVI 420 +V+L Y+ Q + AV+ Sbjct: 462 SSVSLGYLNQSFQNAVM 478 Score = 48.7 bits (116), Expect = 5e-08 Identities = 28/118 (23%), Positives = 48/118 (40%), Gaps = 18/118 (15%) Query: 362 MDLITTAPTVVYQVMQRDGTTVQVENPAKMPDPSKIESILEPIVTVNLYMPQEYVGAVIT 421 D AP V+ QV+++ GT +LEP ++ +Y PQEY+ T Sbjct: 514 ADFRMLAPIVLEQVLKKAGTE-----------------LLEPYLSFKIYAPQEYLSRAYT 556 Query: 422 LCEQKRGSQINMSYHGRQVQLTYEIPMGEIVLDFFDRLKSVSRGYASMDYEFKEYRPS 479 + + ++ +V L+ EIP I ++ L + G + E K Y + Sbjct: 557 DAPKYCANIVDTQLKNNEVILSGEIPARCI-QEYRSDLTFFTNGRSVCLTELKGYHVT 613
>SECA#SecA protein signature. Length = 901 Score = 29.8 bits (67), Expect = 0.011 Identities = 10/46 (21%), Positives = 23/46 (50%), Gaps = 1/46 (2%) Query: 105 RPPELVARLDALIRRVAVSRAVRAAEIKL-GHYTVDRQNRSIHLRE 149 E+ R++ +I + + + GH++VD ++R ++L E Sbjct: 231 DSSEMYKRVNKIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTE 276
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 41.8 bits (98), Expect = 4e-06 Identities = 31/164 (18%), Positives = 62/164 (37%), Gaps = 11/164 (6%) Query: 10 WIIALVCLGTITNYLARNSLGVLAPQLKTELGMSTQQYSYVVGAFQIGYTIMQPVCGFIV 69 W+ L + + L V P + + ++V AF + ++I V G + Sbjct: 18 WLCILSFFSVLNEMV----LNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLS 73 Query: 70 DLIGLR----IGFALFAVLWSIAGCLHAGASGWLSLASFRGLMGLTEAAAIPSGMKAVAE 125 D +G++ G + S+ G + L +A F + G AA M VA Sbjct: 74 DQLGIKRLLLFGIIIN-CFGSVIGFVGHSFFSLLIMARF--IQGAGAAAFPALVMVVVAR 130 Query: 126 WFPDKEKSVAVGYFNAGTSLGALLAPPLVVFLSLRYGWQSAFVV 169 + P + + A G + ++G + P + ++ W ++ Sbjct: 131 YIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLI 174
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 92.6 bits (230), Expect = 4e-23 Identities = 77/357 (21%), Positives = 120/357 (33%), Gaps = 59/357 (16%) Query: 28 AAAQSSVTLYGVVDTAFAYSSNQGGHS-----NTYMSQGNLLASKFGLSGTEDLGGGTQA 82 AA + VTLYG + S + + + L SK G G EDLG G +A Sbjct: 15 VAAMADVTLYGTIKAGVETSRSVAHNGAQAASVETGTGIVDLGSKIGFKGQEDLGNGLKA 74 Query: 83 LFRLESGFNSATGAQAAAGYLFNRLAFVGLSDKTYGALTLGRQYTPYFQYVAALGPTNVL 142 ++++E + A NR +F+GL +G L +GR + + Sbjct: 75 IWQVEQKASIAGTDSG----WGNRQSFIGLK-GGFGKLRVGRLNSVLKDTGDINPWDSKS 129 Query: 143 T---GATGAHPGDVDALDTTLRFNNSVTYTLPVIGGLQAGVQYGMGEQPGSISGGSSFSA 199 A P SV Y P GL VQY + + G S+ A Sbjct: 130 DYLGVNKIAEPEA---------RLISVRYDSPEFAGLSGSVQYALNDNAGR-HNSESYHA 179 Query: 200 ALRYDYQAFAWSAGYIHLKNIPTSNSVGTFANNSPVNSGYASADSAQLIATAARYTFGKL 259 Y F G G + + V + + Q+ + Y L Sbjct: 180 GFNYKNGGFFVQYG-------------GAYKRHHQVQEN-VNIEKYQIHRLVSGYDNDAL 225 Query: 260 MVGLNYSNVQYKPGAGSLFTQAAMFNS-YGLISTYA-----LTPAITVAAGYSYTAEKAR 313 Y++V + L + NS + +T A +TP + Y++ + + Sbjct: 226 -----YASVAVQQQDAKLVEENYSHNSQTEVAATLAYRFGNVTPRV----SYAHGFKGSF 276 Query: 314 NGISSPARYHQFSMEQTYALSKRTAFYALEAYQKASGKTLRTVGGVSTIVDTVASVG 370 + + Y Q + Y SKRT+ S L+ G S V T VG Sbjct: 277 DATNYNNDYDQVVVGAEYDFSKRTSAL-------VSAGWLQEGKGESKFVSTAGGVG 326
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 74.1 bits (182), Expect = 7e-17 Identities = 76/355 (21%), Positives = 130/355 (36%), Gaps = 55/355 (15%) Query: 8 LSLLLAAPALASAQSVTLYGVVDTGVEYVNRIGTTGN--SVVRMPNLSGTVPSRWGLRGM 65 ++L LAA +A+ VTLYG + GVE + G + V + S+ G +G Sbjct: 6 IALTLAALPVAAMADVTLYGTIKAGVETSRSVAHNGAQAASVETGTGIVDLGSKIGFKGQ 65 Query: 66 EDLGGGTRALFALESGFATDSGTANQGGRLFGRQAWVGLSNSSWGQLSFGRQYTMLF--- 122 EDLG G +A++ +E + A RQ+++GL +G+L GR ++L Sbjct: 66 EDLGNGLKAIWQVEQK----ASIAGTDSGWGNRQSFIGLK-GGFGKLRVGRLNSVLKDTG 120 Query: 123 ----WATLDTDLLGPNAYGSSSLDNYLPNARADNAIAYKGKFGGLTVGATYSFGRDTVNA 178 W +D LG N + L + R D+ +F GL+ Y+ + Sbjct: 121 DINPW-DSKSDYLGVNKIAEP--EARLISVRYDSP-----EFAGLSGSVQYALNDN---- 168 Query: 179 GPSPSGTNCAGENPADSLACREWSAMLMYETGRWGLSAAY------DSLRGGPGAFAGLT 232 AG + ++S + A Y+ G + + + Sbjct: 169 ---------AGRHNSES-----YHAGFNYKNGGFFVQYGGAYKRHHQVQENVNIEKYQIH 214 Query: 233 SSALKDDRLAL--GGYALFDNARIGLGWIGR--RNGALATPRSDLFYAGAAYDVTPALTL 288 D AL +A++ + AT + V+ A Sbjct: 215 RLVSGYDNDALYASVAVQQQDAKLVEENYSHNSQTEVAATLAYR--FGNVTPRVSYAHGF 272 Query: 289 AGEVFHLRYHNSANKAWLGAVRASYALSKRSSVYATVGYIDNGGSLALSVSSAAT 343 G Y+N ++ +G A Y SKR+S + G++ G + VS+A Sbjct: 273 KGSFDATNYNNDYDQVVVG---AEYDFSKRTSALVSAGWLQEGKGESKFVSTAGG 324
>PF05043#Transcriptional activator Length = 493 Score = 31.8 bits (72), Expect = 0.003 Identities = 15/54 (27%), Positives = 27/54 (50%) Query: 8 LNLLVVFNELLRQRRVSAVAETLGITQPAISNALNRLRKLLGDELFVRTSKGMI 61 L LL + E R S +AE L T+ A+ + L+ ++ D +F ++ G+ Sbjct: 13 LELLELLFEHKRWFHRSELAELLNCTERAVKDDLSHVKSAFPDLIFHSSTNGIR 66
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 56.4 bits (136), Expect = 1e-10 Identities = 40/160 (25%), Positives = 73/160 (45%), Gaps = 4/160 (2%) Query: 48 APALAQDWHIGPAVLGTVFSAGLAGLMVGALIFGPLADRIGRKQTLLFTVGAFGLASVLS 107 P +A D++ PA V +A + +G ++G L+D++G K+ LLF + SV+ Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 108 AFAPS-VGALVALRFLTGLGLGGAMPNAIA-LTSEYCPERRRAFLTTVMFCGFTLGSGFG 165 S L+ RF+ G G A P + + + Y P+ R ++ +G G G Sbjct: 97 FVGHSFFSLLIMARFIQGAG-AAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVG 155 Query: 166 GIVAAQLVPEFGWRSVLLFGGVIPLLLLPVMVFALPESVR 205 + + W +LL +I ++ +P ++ L + VR Sbjct: 156 PAIGGMIAHYIHWSYLLLI-PMITIITVPFLMKLLKKEVR 194
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 27.8 bits (62), Expect = 0.004 Identities = 8/29 (27%), Positives = 16/29 (55%), Gaps = 1/29 (3%) Query: 1 MKRRLLMWILWPAFLAAALAELVVFSVVD 29 MK+ L+ L A AA+A++ ++ + Sbjct: 1 MKKSLIALTL-AALPVAAMADVTLYGTIK 28
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 124 bits (312), Expect = 4e-33 Identities = 87/405 (21%), Positives = 179/405 (44%), Gaps = 13/405 (3%) Query: 23 VLFTLTVGAVSSIISATIVNVAIPDLSRHFVLGQERAQWVSASFMVAMTLAMLLTPWLLL 82 +L L + + S+++ ++NV++PD++ F WV+ +FM+ ++ + L Sbjct: 15 ILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSD 74 Query: 83 RFGLRRTFIGALLLLGVGGLVGGLSPTY-GVMIAMRVVGGVAAGIMQPLPNILILRVFPE 141 + G++R + +++ G ++G + ++ ++I R + G A L +++ R P+ Sbjct: 75 QLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPK 134 Query: 142 REQGKAFGLFGFGVVLAPALGPSLGGFLVELFGWRSIFFVVVPFTLLGWAMARRFMAINS 201 +GKAFGL G V + +GP++GG + W S ++ T++ + + Sbjct: 135 ENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHW-SYLLLIPMITIITVPFLMKLLKKEV 193 Query: 202 SMAGEPKPLDWRGLLLVGAATVALLNGLVELHADVTRGVALMAVSAVCLAVFLFWQRRVE 261 + G D +G++L+ V + + ++ + VS + +F+ R+V Sbjct: 194 RIKG---HFDIKGIILMSVGIVFFMLFT------TSYSISFLIVSVLSFLIFVKHIRKVT 244 Query: 262 SPLLDLRLFSYRQFAMGAVVAFIYGAGLYGSTYLLPVYMQVALAYTPSSAGLVLLPPG-L 320 P +D L F +G + I + G ++P M+ + + G V++ PG + Sbjct: 245 DPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTM 304 Query: 321 ALAATIVVAGRLTSRIEPYRLVSFGLAALAVSFLLMTTNTRATGYLLLIGIAAIGRVGLG 380 ++ + G L R P +++ G+ L+VSFL + T + + I I + GL Sbjct: 305 SVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFV-LGGLS 363 Query: 381 FVLPSLSLGAMRGVDFTLIPQGSSAVNFLRQLGGAIGVSATGIFL 425 F +S + G S +NF L G++ G L Sbjct: 364 FTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLL 408
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 43.4 bits (102), Expect = 7e-08 Identities = 18/74 (24%), Positives = 30/74 (40%) Query: 90 NVTVAPAWQRQGLGRWLLRAAQALTLAHGFASLLLEVRPSNAGAIALYRRVGFAEIGRRK 149 ++ VA ++++G+G LL A + F L+LE + N A Y + F Sbjct: 94 DIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGAVDT 153 Query: 150 RYYPAENNTREDAL 163 Y E A+ Sbjct: 154 MLYSNFPTANEIAI 167
>SURFACELAYER#Lactobacillus surface layer protein signature. Length = 439 Score = 28.9 bits (64), Expect = 0.029 Identities = 13/71 (18%), Positives = 28/71 (39%) Query: 48 VADAPAPRIEASPVVVAEVVPVAAPAAAAAATVADVPTDSTVPTDSTDPVAPRAQRIAAF 107 + A A + A + A +PV A A + + T++ D T ++ A + Sbjct: 7 IVSAAAAALLAVAPIAATAMPVNAATTINADSAINANTNAKYDVDVTPSISAIAAVAKSD 66 Query: 108 DWAQLEAAVSG 118 + +++G Sbjct: 67 TMPAIPGSLTG 77
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 419 bits (1080), Expect = e-149 Identities = 211/359 (58%), Positives = 256/359 (71%), Gaps = 4/359 (1%) Query: 1 MPRPIQAVIHGPALVNNLQVVRRHAADSRVWAVIKANAYGHGIERAYEGLRQADGFGLLD 60 M RPIQA + AL NL +VR+ A +RVW+V+KANAYGHGIER + + DGF LL+ Sbjct: 1 MTRPIQASLDLQALKQNLSIVRQAATHARVWSVVKANAYGHGIERIWSAIGATDGFALLN 60 Query: 61 LDEAVRLRQLGWQGPILLLEGFFKPEDLALVEQYRLTTTVHCEEQLRMLELARLKGPVSI 120 L+EA+ LR+ GW+GPIL+LEGFF +DL + +Q+RLTT VH QL+ L+ ARLK P+ I Sbjct: 61 LEEAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQNARLKAPLDI 120 Query: 121 QLKINTGMSRLGFAPAAYRAAWEHARAISGIGTIVHMTHFSDADGPRGIDHQLAAFEQAT 180 LK+N+GM+RLGF P W+ RA++ +G + M+HF++A+ P GI +A EQA Sbjct: 121 YLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHFAEAEHPDGISGAMARIEQAA 180 Query: 181 QGLPGEASLSNSAATLWHPRAHRDWVRPGVILYGASPTGVAADIEGTGLMPAMTLKSELI 240 +GL SLSNSAATLWHP AH DWVRPG+ILYGASP+G DI TGL P MTL SE+I Sbjct: 181 EGLECRRSLSNSAATLWHPEAHFDWVRPGIILYGASPSGQWRDIANTGLRPVMTLSSEII 240 Query: 241 AVQDLQPGATVGYGSRFEAEQPMRIGIVACGYADGYPRHAPGWDGNYTPVLVDGVRTRMV 300 VQ L+ G VGYG R+ A RIGIVA GYADGYPRHAP TPVLVDGVRT V Sbjct: 241 GVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAP----TGTPVLVDGVRTMTV 296 Query: 301 GRVSMDMITVDLAEVPGARVGAPVTLWGQGLPIDEVAHAAGTVGYELMCALAPRVPVTV 359 G VSMDM+ VDL P A +G PV LWG+ + ID+VA AAGTVGYELMCALA RVPV Sbjct: 297 GTVSMDMLAVDLTPCPQAGIGTPVELWGKEIKIDDVAAAAGTVGYELMCALALRVPVVT 355
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 29.1 bits (65), Expect = 0.046 Identities = 15/74 (20%), Positives = 29/74 (39%), Gaps = 12/74 (16%) Query: 106 LLQALSNLAASRRVLYVSGEESGAQIALRARRLGVESPNLALLAEIQLERIQATIEAEKP 165 LL AL ++ S +L + + +I L L ++Q+E A ++ + Sbjct: 361 LLDALLEISDSDPLLRYYVDSATHEIILS------------FLGKVQMEVTCALLQEKYH 408 Query: 166 EVVVIDSIQTLYSE 179 + I +Y E Sbjct: 409 VEIEIKEPTVIYME 422
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 31.2 bits (70), Expect = 0.003 Identities = 22/84 (26%), Positives = 31/84 (36%), Gaps = 12/84 (14%) Query: 98 VSFHGRRDHRPFVLTGGVGLHALIDFQHALGAALERAGLRVPQARFVPHVTLLYDRGGFA 157 V+F G+ + F+LTGG L+ G G R PH D G + Sbjct: 669 VTFKGKSEQNRFLLTGGTNLN---------GDLTVEKGTLFLSGRPTPHA---RDIAGIS 716 Query: 158 PKPIEPIAWTVREFVLIDSWLGRT 181 +P E V+ D W+ R Sbjct: 717 STKKDPHFAENNEVVVEDDWINRN 740
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 57.9 bits (140), Expect = 2e-11 Identities = 82/365 (22%), Positives = 135/365 (36%), Gaps = 33/365 (9%) Query: 22 GVSLLMDVASEMIHSLLPMFMVSALGASALTVGLVEGLAESTALIVKIFSGALSDYLGRR 81 G+ L+M V ++ L+ G++ L GALSD GRR Sbjct: 20 GIGLIMPVLPGLLRDLVHS------NDVTAHYGILLALYALMQFACAPVLGALSDRFGRR 73 Query: 82 KGLAVFGYALGAVSKPLFALAPTAGLVLAARLLDRVGKGVRGAPRDALVADIAPPELRGA 141 L + A AV + A AP ++ R++ + G GA A +ADI + R Sbjct: 74 PVL-LVSLAGAAVDYAIMATAPFLWVLYIGRIVAGI-TGATGAVAGAYIADITDGDERAR 131 Query: 142 AFGLRQSLDTVGAFLGPLLAVGLMLRWANDFRAVFWVAVVPGLLSVALLAFGLREPAAR- 200 FG + G GP+L GLM ++ A F+ A L+ F L E Sbjct: 132 HFGFMSACFGFGMVAGPVLG-GLMGGFSP--HAPFFAAAALNGLNFLTGCFLLPESHKGE 188 Query: 201 ---AATHRANPIRRANLRRLTRAYWWVVAIGAVFTLARFSEAFLVLRAQ----RGGVPIA 253 NP+ R ++A+ F + + L R Sbjct: 189 RRPLRREALNPLASFRWARGMTVVAALMAVF--FIMQLVGQVPAALWVIFGEDRFHWDAT 246 Query: 254 LVPLVMVAMNVVYAL-SAYPFGKLSDRVSHTGLLALGLVV-LIAADLVLGATDHWGAVLA 311 + + + A ++++L A G ++ R+ L LG++ L+ AT W A Sbjct: 247 TIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPI 306 Query: 312 GVALWGVHMGI--TQGLLATMVADTAPADLRGTAYGAFNLVSGIAMLVASAL-------- 361 V L +G+ Q +L+ V + L+G+ +L S + L+ +A+ Sbjct: 307 MVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASITTW 366 Query: 362 AGWLW 366 GW W Sbjct: 367 NGWAW 371
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 38.2 bits (89), Expect = 3e-05 Identities = 12/24 (50%), Positives = 15/24 (62%) Query: 1 MSILVTGATGFVGGAIAANLAEKG 24 M LVTGA GF+G ++ L E G Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAG 24
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 66.8 bits (163), Expect = 6e-14 Identities = 54/332 (16%), Positives = 121/332 (36%), Gaps = 22/332 (6%) Query: 47 MANLMFSIAGPHIEGGVLASQDVYLWAVTSYAAAASLAILVMGRLADRMTYRRHTLLSLL 106 + ++ +++ P I W T++ S+ V G+L+D++ +R L ++ Sbjct: 28 LNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGII 87 Query: 107 IFIAGTLMCAAAEGG-TMLIFGRAVQGFGGGPMLSTSRIFVQHSPAHERRTMMKGMIYGI 165 I G+++ ++LI R +QG G + + V E R G+I I Sbjct: 88 INCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSI 147 Query: 166 FGL-TCVSPVLSAALTEQFGWRAIFVAQLLVAVMVCGLVAAFYPHPHQHERTGDFASLDW 224 + V P + + W + + ++ + V L+ + R D Sbjct: 148 VAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKL----LKKEVRIKG--HFDI 201 Query: 225 PSAIAFGLAALIALHGFQQARFVHPDGSPAQVLPILAVVALVAWIG-IRQTGHPLPWVDL 283 I + + + I++V++ + ++ IR+ P VD Sbjct: 202 KGIILMSVGIVFFMLFTTSYSISF---------LIVSVLSFLIFVKHIRKVTDPF--VDP 250 Query: 284 RATLQRRFIVGMVFYAIYYGFASAWSFLSSSLLQNGLGFR-YETTAQFMSLSGLVTLLLG 342 F++G++ I +G + + + ++++ E + + + ++ G Sbjct: 251 GLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFG 310 Query: 343 IANFQLTDYLPRKHVLIAIGFVLMAGAMLWLS 374 L D +VL IG ++ + L S Sbjct: 311 YIGGILVDRRGPLYVLN-IGVTFLSVSFLTAS 341
>TETREPRESSOR#Tetracycline repressor protein signature. Length = 218 Score = 26.8 bits (59), Expect = 0.012 Identities = 12/36 (33%), Positives = 23/36 (63%) Query: 12 VEAVNQVLDRGHSVAEVAQRLGVSQHSLYQWIKQRR 47 +E +N+ G + ++AQ+LG+ Q +LY +K +R Sbjct: 14 LELLNETGIDGLTTRKLAQKLGIEQPTLYWHVKNKR 49
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 34.7 bits (79), Expect = 2e-04 Identities = 18/133 (13%), Positives = 35/133 (26%), Gaps = 8/133 (6%) Query: 56 AAAVQIYEPSALSILQQAQAAATANSAAGKTKAIANEPPKASSKNASTTDAPPKRGPGRP 115 A + + Q + K A + KA + T + P P Sbjct: 1072 AKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSP 1131 Query: 116 PKNAGAAAAKAEVTSSQSEDDSEDTGAPEVDPRQMSLVTPEPEATPAATDTP--PPAEAS 173 + ++E Q+E E+ + Q T PA + Sbjct: 1132 KQ------EQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTE 1185 Query: 174 PQPSDATPAVADS 186 + +V ++ Sbjct: 1186 STTVNTGNSVVEN 1198 Score = 30.8 bits (69), Expect = 0.004 Identities = 31/138 (22%), Positives = 47/138 (34%), Gaps = 9/138 (6%) Query: 63 EPSALSILQQAQAAATANSAAGKTKAIANEPPK-ASSKNASTTDAPPKRGPGRPPKNAGA 121 E A + Q+++ A +T A E K A S + T G K Sbjct: 1038 ETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQT 1097 Query: 122 AAAKAEVTSSQSEDDSEDTG--------APEVDPRQMSLVTPEPEATPAATDTPPPAEAS 173 K T + E +T +V P+Q T +P+A PA + P Sbjct: 1098 TETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKE 1157 Query: 174 PQPSDATPAVADSDPRKT 191 PQ T A + ++T Sbjct: 1158 PQSQTNTTADTEQPAKET 1175
>ENTSNTHTASED#Enterobactin synthetase component D signature. Length = 234 Score = 29.2 bits (65), Expect = 0.023 Identities = 28/110 (25%), Positives = 40/110 (36%), Gaps = 19/110 (17%) Query: 227 FLAGRIAARIGRAESRL-VVQGTGD-GKPQQPQGLAASVTLTKSTANAAKLTWQEVNTLI 284 LAGRIAA E + V G GD +P P GL S++ +TA A ++ Q + I Sbjct: 50 HLAGRIAAVHALREVGVRTVPGMGDKRQPLWPDGLFGSISHCATTA-LAVISRQRIGIDI 108 Query: 285 HAVDPAYRNAPMYRLAFNDQTLKVLEELVDGNGRPLWLPGLESSAPPTIL 334 + + EL L++S P L Sbjct: 109 EKIMSQH----------------TATELAPSIIDSDERQILQASLLPFPL 142
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 28.2 bits (63), Expect = 0.026 Identities = 15/46 (32%), Positives = 26/46 (56%), Gaps = 5/46 (10%) Query: 84 VYVFDEPAAPSGQPGLQVFKADGTLAFDSG-----LAYLKVSGVVT 124 V++ +EP A + GL V +A G++ D G +A + ++GVV Sbjct: 138 VFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNGVVY 183
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.6 bits (69), Expect = 0.013 Identities = 15/90 (16%), Positives = 34/90 (37%), Gaps = 16/90 (17%) Query: 67 LPTPHEIRQSLDQYVIGQEQAKKILAVAVYNHYKRLKHLGKKDDVELSKSNILLIGPTGS 126 P+ E ++G+ A + + + + + + +++ G +G+ Sbjct: 125 RPSKLEDDSQDGMPLVGRSAA-----------MQEIYRVLAR--LMQTDLTLMITGESGT 171 Query: 127 GKTLLAQTLARL---LNVPFVIADATTLTE 153 GK L+A+ L N PFV + + Sbjct: 172 GKELVARALHDYGKRRNGPFVAINMAAIPR 201
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 28.8 bits (64), Expect = 0.009 Identities = 15/78 (19%), Positives = 25/78 (32%), Gaps = 13/78 (16%) Query: 51 TEVVEAFGVDFYVVKST-LEYHASARFDDVLDLRCRVARLGRSSLRFIIEIYRGEGDDRA 109 + +++ V + +E H D V L S IY G+G D Sbjct: 594 SNLIQHASVGNNQYREIRIESHLGDGDDKVF--------LSAGS----ANIYAGKGHDVV 641 Query: 110 HLVTGEVIYVCADPATQT 127 + + Y+ D T Sbjct: 642 YYDKTDTGYLTIDGTKAT 659
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.1 bits (83), Expect = 2e-05 Identities = 17/56 (30%), Positives = 27/56 (48%), Gaps = 3/56 (5%) Query: 76 IGRMAVRKEARGTGIGARVLQALIDKARALGYTQLILNAQTHAMP---FYARAGFT 128 I +AV K+ R G+G +L I+ A+ + L+L Q + FYA+ F Sbjct: 92 IEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFI 147
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 32.0 bits (72), Expect = 0.003 Identities = 23/62 (37%), Positives = 27/62 (43%), Gaps = 5/62 (8%) Query: 225 PGAQPVPARQPAAPAGMRPAAPVVPDV-PAPMPAPRA-PESAIDRDATSGLPGSLSDQKT 282 P AQP+P PA PA P P P P P P++ D D G PG+ D Sbjct: 323 PNAQPLPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTD---GQPGTRPDSPA 379 Query: 283 VP 284 VP Sbjct: 380 VP 381
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.5 bits (63), Expect = 0.049 Identities = 9/22 (40%), Positives = 14/22 (63%) Query: 45 LVLLGPSGCGKTTTLRIVAGLE 66 +VL G G GK+T + + GL+ Sbjct: 599 VVLEGTGGIGKSTLINTLVGLD 620
>SECETRNLCASE#Bacterial translocase SecE signature. Length = 127 Score = 27.9 bits (62), Expect = 0.034 Identities = 10/48 (20%), Positives = 23/48 (47%), Gaps = 2/48 (4%) Query: 69 GQEAIGVGVASAMRAEDVLFPSYRD--HSAQLLRGVSMAESLLYWGGD 114 G+ + + V++P+ ++ H+ ++ V+ SL+ WG D Sbjct: 65 GKATVAFAREARTEVRKVIWPTRQETLHTTLIVAAVTAVMSLILWGLD 112
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 34.4 bits (79), Expect = 0.009 Identities = 36/156 (23%), Positives = 59/156 (37%), Gaps = 26/156 (16%) Query: 1842 YLVAGAYGALGRHTTDWLAAHGATHLVLA----GRRAPPAGWQARLALLRAQGVRIDPVD 1897 YLV GA G +G H + L G H V+ + QARL LL G + Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAG--HQVVGIDNLNDYYDVSLKQARLELLAQPGFQF--HK 58 Query: 1898 ADLAEAADVERLFDAVAALEATTGRTLAGVFHCAGTSRFNDLAGL--TTDDCAAVTGAKM 1955 DLA+ + LF + VF + + ++ A + + Sbjct: 59 IDLADREGMTDLFASG---HFER------VFISPHR------LAVRYSLENPHAYADSNL 103 Query: 1956 TGAWLLHEQTRARRLDWFVCFTSISGVWGSRLQIPY 1991 TG + E R ++ + + S S V+G ++P+ Sbjct: 104 TGFLNILEGCRHNKIQHLL-YASSSSVYGLNRKMPF 138
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 34.2 bits (78), Expect = 0.005 Identities = 19/42 (45%), Positives = 25/42 (59%) Query: 1798 LRAGIATLLHCAPDTITDQANLIQLGLDSLLFLELCETIARE 1839 +R IA LL P+ ITDQ +L+ GLDS+ + L E RE Sbjct: 235 IRKQIAELLQETPEDITDQEDLLDRGLDSVRIMTLVEQWRRE 276 Score = 32.3 bits (73), Expect = 0.023 Identities = 15/71 (21%), Positives = 36/71 (50%), Gaps = 1/71 (1%) Query: 1681 DTVRARVAEVLGRDAQAIPAEANLIQLGLDSLLFLDLSERLGKQFGVSISAETAFKANTL 1740 + +R ++AE+L + I + +L+ GLDS+ + L E+ ++ G ++ + T+ Sbjct: 233 ENIRKQIAELLQETPEDITDQEDLLDRGLDSVRIMTLVEQWRRE-GAEVTFVELAERPTI 291 Query: 1741 NAFVQALAAQL 1751 + + L + Sbjct: 292 EEWQKLLTTRS 302
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 52.4 bits (125), Expect = 8e-09 Identities = 76/387 (19%), Positives = 125/387 (32%), Gaps = 31/387 (8%) Query: 455 GAPYALSTEQVVAIASHNGGKQALEAVKADLLELRGAPYALSTEQVVAIASHNGGKQA-- 512 GA ++T V+ + LE V+ + + ++ +N + Sbjct: 30 GAGLVVNTN-EVSAVATRSQTDTLEKVQERADKFEI-ENNTLKLKNSDLSFNNKALKDHN 87 Query: 513 ------LEAVKAHLLDLRGVPYALSTEQVVAIASHNGGKQALEAVKAQLLDLRGAPYALS 566 L K L +++ A ++ALE L Sbjct: 88 DELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLE 147 Query: 567 TAQVVAIASNGGGKQALEGIGEQLLKLRTAPYGLSTEQVVAIASHDGGKQALEAVGAQLV 626 + A ++ALEG L E K ALEA A+L Sbjct: 148 AEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAE-----------KAALEARQAELE 196 Query: 627 ALRAAPYALSTEQVVAIASNKGGKQALEAVKAQLLELRGAPYALSTAQVVAIASHDGGNQ 686 ST I + + K AL A KA L + STA I + + Sbjct: 197 KALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKA 256 Query: 687 ALEAVGTQLVALRAAPYALSTEQVVAIASHDGGKQALEAVGAQLVALRAAPYALNTEQVV 746 ALEA +L A+ ++ + A+ AL A L + V Sbjct: 257 ALEARQAELEKALE----------GAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQV 306 Query: 747 AIASSHGGKQALEAVRALFPDLRAAPYALSTAQLVAIASNPGGKQALEAVRALFRELRAA 806 A+ ++ L+A R L A L ++ AS ++ L+A R ++L A Sbjct: 307 LNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAE 366 Query: 807 PYALSTEQVVAIASNHGGKQALEAVRA 833 L + ++ AS ++ L+A R Sbjct: 367 HQKLEEQNKISEASRQSLRRDLDASRE 393 Score = 48.1 bits (114), Expect = 2e-07 Identities = 75/383 (19%), Positives = 125/383 (32%), Gaps = 29/383 (7%) Query: 490 GAPYALSTEQVVAIASHNGGKQALEAVKAHLLDLRGVPYALSTEQVVAIASHNGGKQALE 549 GA ++T V+ + LE V+ L + ++ K + Sbjct: 30 GAGLVVNTN-EVSAVATRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHND 88 Query: 550 AVKAQLLDLRGAPYALSTAQVVAIASNGGGKQALEGIGEQL-------LKLRTAPYGLST 602 + +L + + + + + + + L L Sbjct: 89 ELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEA 148 Query: 603 EQVVAIASHDGGKQALEAVGAQLVALRAAPYALSTEQVVAIASNKGGKQALEAVKAQLLE 662 E+ A ++ALE A A L E K ALEA +A+L + Sbjct: 149 EKAALAARKADLEKALEGAMNFSTADSAKIKTLEAE-----------KAALEARQAELEK 197 Query: 663 LRGAPYALSTAQVVAIASHDGGNQALEAVGTQLVALRAAPYALSTEQVVAIASHDGGKQA 722 STA I + + AL A L ST I + + K A Sbjct: 198 ALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAA 257 Query: 723 LEAVGAQLVALRAAPYALNTEQVVAIASSHGGKQALEAVRALFPDLRAAPYALSTAQLVA 782 LEA A+L +T I + K ALEA +A L V Sbjct: 258 LEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKA----------DLEHQSQVL 307 Query: 783 IASNPGGKQALEAVRALFRELRAAPYALSTEQVVAIASNHGGKQALEAVRALFRGLRAAP 842 A+ ++ L+A R ++L A L + ++ AS ++ L+A R + L A Sbjct: 308 NANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEH 367 Query: 843 YGLSTAQVVAIASSNGGKQALEA 865 L ++ AS ++ L+A Sbjct: 368 QKLEEQNKISEASRQSLRRDLDA 390
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 32.6 bits (74), Expect = 3e-04 Identities = 20/96 (20%), Positives = 39/96 (40%), Gaps = 6/96 (6%) Query: 40 ERIEGDESLIFVADAGNNALVGFCQLYPTFCSVAAAPIYVLYDLFVSPTVRRQGIAKQLL 99 +E + F+ NN +G ++ + A ++ D+ V+ R++G+ LL Sbjct: 58 SYVEEEGKAAFLYYLENN-CIGRIKIRSNWNGYA-----LIEDIAVAKDYRKKGVGTALL 111 Query: 100 QAAAYQAKVDGKARIDLTTGKQNVNAQALYEMLGWK 135 A AK + + L T N++A Y + Sbjct: 112 HKAIEWAKENHFCGLMLETQDINISACHFYAKHHFI 147
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 110 bits (275), Expect = 4e-31 Identities = 77/254 (30%), Positives = 115/254 (45%), Gaps = 12/254 (4%) Query: 2 KGLEGKVAIVTGGATLIGAAVVRTLRSYRVKVALFDIDAASGNRVAAEDSDGTRF---WP 58 KG+EGK+A +TG A IG AV RTL S +A D + +V + R +P Sbjct: 4 KGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP 63 Query: 59 VDITDDRQLERGVADAAAHFGRVDFLVNLAATYLDDGA--KSGREDWLKALDVNLVSAVM 116 D+ D ++ A G +D LVN A L G E+W VN Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVN-VAGVLRPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 117 AARAVHPHLAAAGGGAIVNFTSISSKVAQTGRWLYPVSKAALVQLTRGMAMDYAADGIRV 176 A+R+V ++ G+IV S + V +T Y SKAA V T+ + ++ A IR Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 177 NSVSPGWTWSRVMDALTHGDRAKTDRVAADYHL------LRRVGDPEEVAEVVAFLLSGH 230 N VSPG T + + +L + + L+++ P ++A+ V FL+SG Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 231 AAFVTGADYAVDGG 244 A +T + VDGG Sbjct: 243 AGHITMHNLCVDGG 256
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 32.9 bits (75), Expect = 0.003 Identities = 6/51 (11%), Positives = 21/51 (41%) Query: 1 MGRPDTITMSMRELDRCKVIQAVADDGLMVWRAAEKLGISKRQVERLVLRY 51 + + E++ ++ A+ +AA+ LG+++ + + + Sbjct: 423 LPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIREL 473
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 116 bits (293), Expect = 2e-30 Identities = 85/426 (19%), Positives = 166/426 (38%), Gaps = 21/426 (4%) Query: 1 MTTPSSDSQAPLTGGMLWLAAIVLAAANFVAVLDMTIANVSVPNISGNLGVSTSQGTWVI 60 M T S S ++WL + F +VL+ + NVS+P+I+ + + WV Sbjct: 1 MNTSYSQSNLRHNQILIWLCILS-----FFSVLNEMVLNVSLPDIANDFNKPPASTNWVN 55 Query: 61 TSYAVAEAILVPLTGWLASRFGTVRVFAVAMGCFGLFSALCGLALS-LGMLVAARICQGL 119 T++ + +I + G L+ + G R+ + S + + S +L+ AR QG Sbjct: 56 TAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGA 115 Query: 120 AGGPLMPLSQTLLLRIFPKEKAGAAIGLWSMTTIVAPVLGPILGGYLCDEYSWPWIFYIN 179 L ++ R PKE G A GL + +GP +GG + W ++ I Sbjct: 116 GAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIP 175 Query: 180 LPIAVGCAWAAWKMLARYESPIARNPIDKVGLALLVLWVGSLQIMLDEGKQLDWFASSTI 239 + + + + + + D G+ L+ VG + ML F +S Sbjct: 176 MITIITVPFLMKLLK---KEVRIKGHFDIKGIILMS--VGIVFFML--------FTTSYS 222 Query: 240 AGLAVVAAIGFAAFLIWELHAEHPAVNLRVFRHRGFSASVLTISLAFGAFFGANVLTPQW 299 +V+ + F F+ P V+ + ++ F VL + FG G + P Sbjct: 223 ISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYM 282 Query: 300 LQSFMGYTALEAGKTTAWSG-FFALFAAPIAAGLGGKVDARKLVFGGVIWLGIITLWRTV 358 ++ + E G + G + I L + ++ GV +L ++ Sbjct: 283 MKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFL-SVSFLTAS 341 Query: 359 ATTDMTYWQVAVPLMAMGLGIPFFFVPTTGLAMASVDEEEMASAAGLMNFLRTLSGAFAT 418 + T W + + ++ + G+ F + + +S+ ++E + L+NF LS Sbjct: 342 FLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGI 401 Query: 419 SLITTL 424 +++ L Sbjct: 402 AIVGGL 407
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 91.4 bits (227), Expect = 3e-22 Identities = 63/410 (15%), Positives = 124/410 (30%), Gaps = 65/410 (15%) Query: 19 RRARLFLILAAVVAAGAIGGTAYWQLYASRFVSTDNAYAAVEIAQVTPAIDGTIAEVRVS 78 RR RL A + + + ++ P + + E+ V Sbjct: 55 RRPRLVAYFIMGFLVIAFI-LSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVK 113 Query: 79 DTQAVKKGDVLVVIDPTDAKLALEQAEAQLGSA--------------------------- 111 + ++V+KGDVL+ + A+ + ++ L A Sbjct: 114 EGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDE 173 Query: 112 -----------VRRVRGYVANDSSLGAQIIAREADEKRAAADLFSAQA-------DFERA 153 +R S+ Q +E + + A+ + A Sbjct: 174 PYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233 Query: 154 KIDLRRREALVASGSVSGEELTKARNAHATADAARAAPASAQARANRNAAVGSRQANAV- 212 K L +L+ +++ + + N + A S + + V Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVT 293 Query: 213 -----LIANATEDTNPEVALARAKRDQAAVDLGRTVIRAPVDGVVAKRQVQ-LGQRVKSG 266 I + T + L + + +VIRAPV V + +V G V + Sbjct: 294 QLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTA 353 Query: 267 TALLSIVPVQD-MHVDANFKEVQLENVRIGQPATVKADIYGGS--ASYRGVVEGFSGGSG 323 L+ IVP D + V A + + + +GQ A +K + + + G V+ + Sbjct: 354 ETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNIN---- 409 Query: 324 AAFAAIPAQNATGNWIKVVQRLPVRIKLDAAELEKHPLKVGLSMVVTIDT 373 G V+ + + PL G+++ I T Sbjct: 410 ---LDAIEDQRLGLVFNVIISIEENCLS--TGNKNIPLSSGMAVTAEIKT 454
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.3 bits (71), Expect = 0.003 Identities = 20/118 (16%), Positives = 35/118 (29%), Gaps = 5/118 (4%) Query: 18 RTLRTEGYSAAHYADTREFLRSIKRDSHDLVLISHAASHLALSKLPMLIRSRLQQHTPLL 77 + L GY ++ R I DLV+ L I+ + P+L Sbjct: 21 QALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDLLPRIKKA-RPDLPVL 79 Query: 78 LVGHDHDEDAVAASLGAGADGYIALPISP----ALFSARVTALLRRIYPIRAARQTFM 131 ++ + + GA Y+ P + + RR + Q M Sbjct: 80 VMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPSKLEDDSQDGM 137
>TETREPRESSOR#Tetracycline repressor protein signature. Length = 218 Score = 27.6 bits (61), Expect = 0.003 Identities = 13/63 (20%), Positives = 25/63 (39%), Gaps = 12/63 (19%) Query: 1 MKAINIKQVAEKVSLGQSTIYRMITKGEFPKPFSLGGNRTAWLDEDIDAWLAMRAGRPIP 60 + + +++A+K+ + Q T+Y + N+ A LD LA +P Sbjct: 22 IDGLTTRKLAQKLGIEQPTLYWHV------------KNKRALLDALAVEILARHHDYSLP 69 Query: 61 KPG 63 G Sbjct: 70 AAG 72
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.7 bits (72), Expect = 0.012 Identities = 18/188 (9%), Positives = 57/188 (30%), Gaps = 20/188 (10%) Query: 1 MSDARRLRLEVVLAAVDKATRPLRNLMN-------ANNDLARAVKATRAQLKDLERTQAS 53 + + R +++ +++ P L + + ++ R + Q + + Sbjct: 145 QARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQ 204 Query: 54 ID-TFRKLSRDAAITGNQLKAVRGRADELARQLKQTSEPSAALSKAFEAARREAQALKSK 112 + K + ++ + +L ++L A+ ++K Sbjct: 205 KELNLDKKRAERLTVLARINRYENLSRVEKSRLDDF----SSLLHKQAIAKHAVLEQENK 260 Query: 113 QSELSEKLHQVRGRLSEAGIGTQSL--------AEHQRALKTRIAETNQQLEAQTQRMAA 164 E +L + +L + S + + ++ +T + T +A Sbjct: 261 YVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAK 320 Query: 165 VTAQQRRM 172 +Q+ Sbjct: 321 NEERQQAS 328
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 28.4 bits (63), Expect = 0.009 Identities = 24/101 (23%), Positives = 42/101 (41%), Gaps = 9/101 (8%) Query: 25 LPGVDP-----GTVLGAFAGA-AVFALNSGELTVAKKLS--FLLLSIVAGVLSAPLAASL 76 LP +D TV G + A F L++ + K + L + V G + ++ + Sbjct: 232 LPNLDNIGAGLDTVSGILSAISASFILSNADADTRTKAAAGVELTTKVLGNVGKGISQYI 291 Query: 77 IARALPANTEVSEAVGALVASTVMVRLL-LALIRAADNSDK 116 IA+ S A L+AS V + + L+ + AD + Sbjct: 292 IAQRAAQGLSTSAAAAGLIASAVTLAISPLSFLSIADKFKR 332
>SECA#SecA protein signature. Length = 901 Score = 31.4 bits (71), Expect = 0.007 Identities = 24/84 (28%), Positives = 36/84 (42%), Gaps = 11/84 (13%) Query: 119 IVAGLDILIVRELTGDIYFGQPRGVRAAPDGLFAG--AREGFDTMRYSEPEIRRIAHVAF 176 IV +++IV E TG G R DGL A+EG + E + +A + F Sbjct: 327 IVKDGEVIIVDEHTGRTMQG-----RRWSDGLHQAVEAKEGVQI----QNENQTLASITF 377 Query: 177 QAAAKRGKKLCSVDKANVLETFQF 200 Q + +KL + E F+F Sbjct: 378 QNYFRLYEKLAGMTGTADTEAFEF 401
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 32.1 bits (73), Expect = 0.003 Identities = 21/124 (16%), Positives = 42/124 (33%), Gaps = 9/124 (7%) Query: 98 ILVGQAGRRLAYVTVPKVRDVVEVARVTDRVNQA-----ARAAGIARHLPIHVLIETHGA 152 +L L V P + + E+ + + + + ++ + + +++E Sbjct: 378 LLRASTYGNL-KVMFPMIATLEELRQAKAIMQEEKDKLLSEGVDVSDSIEVGIMVEIPST 436 Query: 153 LAQVFDIAALVQVECLSFGLMDFVSAHNGAIPGAAMGSPEQFE-HPLIRRALTDIAAACH 211 A +V+ S G D + A S HP I R + + A H Sbjct: 437 AVAANLFAK--EVDFFSIGTNDLIQYTMAADRMNERVSYLYQPYHPAILRLVDMVIKAAH 494 Query: 212 AHGK 215 + GK Sbjct: 495 SEGK 498
>BINARYTOXINA#Clostridial binary toxin A signature. Length = 454 Score = 30.4 bits (68), Expect = 0.014 Identities = 21/98 (21%), Positives = 30/98 (30%), Gaps = 28/98 (28%) Query: 152 AYYRPGGVYRDLPDSMPQYKASKVRNEKALAAMNETRSGSLLDFIE-------------- 197 Y R G L + P+Y +K+ N A E + + +FI Sbjct: 334 VYRRSGPQEFGLTLTSPEYDFNKIENIDAFKEKWEGKVITYPNFISTSIGSVNMSAFAKR 393 Query: 198 --------------AFTDRFPTYVDEYETLLTDNRIWK 221 A+ P Y EYE LL +K Sbjct: 394 KIILRINIPKDSPGAYLSAIPGYAGEYEVLLNHGSKFK 431
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 61.6 bits (149), Expect = 9e-14 Identities = 21/78 (26%), Positives = 39/78 (50%) Query: 4 KPHATGPRRTRDRILEVSLRLFNELGEPNVTTTTIAEELEISPGNLYYHFRNKDDIINSI 63 + + TR IL+V+LRLF++ G + + IA+ ++ G +Y+HF++K D+ + I Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 64 FVQFEQEISRRLRLPDDH 81 + E I Sbjct: 63 WELSESNIGELELEYQAK 80
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 29.7 bits (67), Expect = 0.024 Identities = 12/28 (42%), Positives = 17/28 (60%), Gaps = 2/28 (7%) Query: 64 AGAQVHDYSGKLIVPGFIDTHIHF--PQ 89 G +V GK++ G +D+HIHF PQ Sbjct: 116 PGTEVIAGEGKIVTAGGMDSHIHFICPQ 143
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 78.3 bits (193), Expect = 3e-18 Identities = 48/207 (23%), Positives = 81/207 (39%), Gaps = 25/207 (12%) Query: 13 AVVTPAF---SQGSVTLYGVLDEGLNYTNNVGGHSQVALASG-----FPHGSRWGLKGAE 64 A+ A + VTLYG + G+ + +V + A + GS+ G KG E Sbjct: 7 ALTLAALPVAAMADVTLYGTIKAGVETSRSVAHNGAQAASVETGTGIVDLGSKIGFKGQE 66 Query: 65 AIGGGIKTIFQLENGFDVDSGRAFQGGLLFGRQAYVGVSSDTLGALTAGRQYDAVVDFLA 124 +G G+K I+Q+E + + G RQ+++G+ G L GR + D Sbjct: 67 DLGNGLKAIWQVEQKASIAGTDSGWG----NRQSFIGLKGG-FGKLRVGRLNSVLKDTGD 121 Query: 125 QN--TAGGTW-GGYMFAHPYDSDNLINTFRTNNAVKYTSPALGGLKFGATYGFSNDVKAS 181 N + + G A P + + +V+Y SP GL Y +++ Sbjct: 122 INPWDSKSDYLGVNKIAEP---EARL------ISVRYDSPEFAGLSGSVQYALNDNAGRH 172 Query: 182 NNRLFSVGGQYTVGGWLLSAAYLQADH 208 N+ + G Y GG+ + H Sbjct: 173 NSESYHAGFNYKNGGFFVQYGGAYKRH 199
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 86.0 bits (213), Expect = 5e-21 Identities = 74/348 (21%), Positives = 123/348 (35%), Gaps = 29/348 (8%) Query: 13 VIAAAL-ALPAHAQSSVTLYGRVVGGVEYIDKVAVPATGKTGSLLQAAGNQWGTSMFGMK 71 +IA L ALP A + VTLYG + GVE VA G S G K Sbjct: 5 LIALTLAALPVAAMADVTLYGTIKAGVETSRSVAHNGAQAASVETGTGIVDLG-SKIGFK 63 Query: 72 GSESLGGGLQALFTLESGFSLPNSALNGPGLFNRRSYVGLSSPSWGTLIVGKNLSISNDI 131 G E LG GL+A++ +E + A G NR+S++GL +G L VG+ S+ D Sbjct: 64 GQEDLGNGLKAIWQVEQK---ASIAGTDSGWGNRQSFIGLKG-GFGKLRVGRLNSVLKDT 119 Query: 132 WDIDPTGQQFMSTATLVKGRNWPGADNM---IEYRSPDLGGFSFGAQASLSEQPAGRRVS 188 DI+P + S + + + + Y SP+ G S Q +L++ Sbjct: 120 GDINP----WDSKSDYLGVNKIAEPEARLISVRYDSPEFAGLSGSVQYALNDNAGRHNSE 175 Query: 189 AQGLSATYQTSDLMLRGIYTERRDSAGAFSDVYNASKDGILGGTYRIGPAKLFAGYERIL 248 + Y+ ++ +R + + L Y ++ Sbjct: 176 SYHAGFNYKNGGFFVQYGGAYKRHHQVQENVNIEKYQIHRLVSGYDNDALYASVAVQQQD 235 Query: 249 ASQTGADTAPSALSQAWLGIRYDLTQAVTLIGAVYHVKS--NQSGGNATL--AMLGVDYY 304 A + + ++ ++ + Y + + K + + N ++G +Y Sbjct: 236 AKLVEENYSHNSQTEVAATLAYRFGNVTPRVSYAHGFKGSFDATNYNNDYDQVVVGAEYD 295 Query: 305 LSKRTFLYASLGGVSNGANADYAADVTAAGPGVGKSQRVVYVGMGHSF 352 SKRT S G + G VG+ H F Sbjct: 296 FSKRTSALVSAGWLQEGKGESKFVSTAGG------------VGLRHKF 331
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 31.1 bits (70), Expect = 0.019 Identities = 11/55 (20%), Positives = 18/55 (32%) Query: 76 TPTRAQPKPDVVPALKPAPRRMRPPAAPGRKHQRNVDAVVPPAMATSPRAEIRFP 130 P + P V+ KP P+ P + +R+V V + P Sbjct: 83 IPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARP 137
>PF05272#Virulence-associated E family protein Length = 892 Score = 31.2 bits (70), Expect = 0.007 Identities = 19/86 (22%), Positives = 30/86 (34%), Gaps = 20/86 (23%) Query: 32 VVFVGPSGCGKSTLMRMIAGLEDISSGDLLIDGAKVNDVPSAKRGIAMVFQSYALYPHMT 91 VV G G GKSTL+ + GL+ S D+ + K Y Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHF--------DIGTGKDS-YEQIAGIVAY---- 645 Query: 92 LYDNMAFGLKLAGAKKAEIDQAVKGA 117 ++ ++A+ +AVK Sbjct: 646 -----ELS-EMTAFRRADA-EAVKAF 664
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 30.5 bits (68), Expect = 0.015 Identities = 66/307 (21%), Positives = 114/307 (37%), Gaps = 37/307 (12%) Query: 124 DSLSYDGQLYALPFYVESSMTFYRKDLFAAKGLTMPDQP-TYDQIAQFADKLTDKDKGVY 182 D++ Y+G+L A P VE+ Y KDL +P+ P T+++I +L K K Sbjct: 121 DAVRYNGKLIAYPIAVEALSLIYNKDL-------LPNPPKTWEEIPALDKELKAKGKSAL 173 Query: 183 GICLRGKAGWGENMAYVSTVVNTFGGRWFDEKWNAQLTSPEWKKAIGFYVNLLKKNGPPG 242 L+ +A + +D K + + + K + F V+L+K Sbjct: 174 MFNLQEPYFTWPLIAADGGYAFKYENGKYDIK-DVGVDNAGAKAGLTFLVDLIKNKHMNA 232 Query: 243 ASSNGFNENLTLTASGKCAMWIDATVAAGMLYNKQQSQVADKIGFAAAPIADTPKGSHWL 302 + E G+ AM I+ A N S+V G P ++ Sbjct: 233 DTDYSIAE--AAFNKGETAMTINGPWAWS---NIDTSKV--NYGVTVLPTFKGQPSKPFV 285 Query: 303 WAWALAIPKTSKQQEAAKTFV-TWATSKQYIEMVGKDEGWASVPPGTRASTYQRAEYKAA 361 + I S +E AK F+ + + + +E V KD+ +V +Y+ K Sbjct: 286 GVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVA----LKSYEEELAK-- 339 Query: 362 APFSDFVLRAIETADPTDPSAKKVPYTGVAYVGIPEFQSFGTVVGQSIAGAVAGQFSVDQ 421 DP + + G IP+ +F V ++ A +G+ +VD+ Sbjct: 340 --------------DPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDE 385 Query: 422 ALAAGQA 428 AL Q Sbjct: 386 ALKDAQT 392
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 65.7 bits (160), Expect = 8e-14 Identities = 45/198 (22%), Positives = 80/198 (40%), Gaps = 6/198 (3%) Query: 22 LLLLGALTAIGPLSVDMYLPSLPTIARDLRTSSAAAGITLTAFLVSLAIGQLIYGPASDR 81 L+ L L+ L+ + SLP IA D A+ TAF+++ +IG +YG SD+ Sbjct: 16 LIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQ 75 Query: 82 FGRKPPLYIGLALYVAASVGCAFA-TDATMLAVLRAVQGFGGCAGMVISRAAVRDRMDPA 140 G K L G+ + SV + ++L + R +QG G A + V + Sbjct: 76 LGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKE 135 Query: 141 GAAQAYSTLMLVMGVAPILAPMIGGAVLQVTSWRMIFAVLAAFGVLSLAAVHFLMRES-- 198 +A+ + ++ + + P IGG + W + + + + L +E Sbjct: 136 NRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRI 195 Query: 199 ---LDAAHARPLAVGRVL 213 D ++VG V Sbjct: 196 KGHFDIKGIILMSVGIVF 213
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 28.6 bits (63), Expect = 0.014 Identities = 15/48 (31%), Positives = 22/48 (45%), Gaps = 2/48 (4%) Query: 97 GEPTIVDLAQHPERG--PKIRTNGFSLPGYHSGWYVGADKRRIFAAIA 142 GEP ++DL H G PK T F P G ++K +F ++ Sbjct: 283 GEPVVIDLGLHSRSGEQPKGFTESFKAPELGVGNLGASEKSDVFLVVS 330
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 29.4 bits (66), Expect = 0.002 Identities = 9/38 (23%), Positives = 14/38 (36%), Gaps = 2/38 (5%) Query: 21 FALRHPEAPWWLTPAALLLAGYVVS--PVDLIPDVIPV 56 F +R P W L ++ + PV P + P Sbjct: 4 FFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPP 41
>AUTOINDCRSYN#Autoinducer synthesis protein signature. Length = 216 Score = 29.0 bits (65), Expect = 0.013 Identities = 26/144 (18%), Positives = 49/144 (34%), Gaps = 24/144 (16%) Query: 51 TTFINLLTGAFAPTAGQVRLDGDDITRLS----AHQRVKRGITRTFQINT-LFPGL---- 101 T + N++TG F P ++ + + S R K + + I++ LF + Sbjct: 72 TKYPNMITGTFFPYFKEINIPEGNYLESSRFFVDKSRAKDILGNEYPISSMLFLSMINYS 131 Query: 102 ---------TVLESVMLAIFERTGASWHWHRTVAAHTAARDEAMALLGRLQLGADASSPT 152 T++ ML I +R+G W V + E L + L D + Sbjct: 132 KDKGYDGIYTIVSHPMLTILKRSG----WGIRVVEQGLSEKEERVYL--VFLPVDDENQE 185 Query: 153 HALPYGKQRLLEIALALATLPRIL 176 + ++ L P + Sbjct: 186 ALARRINRSGTFMSNELKQWPLRV 209
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 26.7 bits (59), Expect = 0.043 Identities = 12/54 (22%), Positives = 22/54 (40%), Gaps = 13/54 (24%) Query: 106 SKQDPQPAAQPAQDERSREDLLKENECLRAEVAYLKKLDALLRAKQQQAPKKKR 159 S +DP ++ ++N L+ L KLD + K + P +K+ Sbjct: 159 SAKDPN-----------NKEFYEKN--LKEYTDKLDKLDKESKDKFNKIPAEKK 199
>AEROLYSIN#Aerolysin signature. Length = 493 Score = 32.7 bits (74), Expect = 0.007 Identities = 12/18 (66%), Positives = 14/18 (77%) Query: 799 DMAIARDGDAWVVRGNGD 816 DM + RDGD WV+RGN D Sbjct: 162 DMDVTRDGDGWVIRGNND 179
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 73.8 bits (181), Expect = 7e-20 Identities = 37/127 (29%), Positives = 62/127 (48%), Gaps = 18/127 (14%) Query: 8 RRRGFTLIELVVVMAIIGLLLTLALPRYFHSIERGRAQVQQQNLAVIRDAIDKYYGDNGQ 67 ++RGFTL+E++VV+ IIG+L +L +P + E+ Q ++ + +A+D Y DN Sbjct: 6 KQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDNHH 65 Query: 68 YPDT---LDDLVAK-------------RYLRGIPVDPVSGGTAWAVIAPPDTSKTGIYDV 111 YP T L+ LV Y++ +P DP G + ++ P + + Sbjct: 66 YPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADP--WGNDYVLVNPGEHGAYDLLSA 123 Query: 112 GPAREAG 118 GP E G Sbjct: 124 GPDGEMG 130
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 39.5 bits (92), Expect = 1e-06 Identities = 31/143 (21%), Positives = 56/143 (39%), Gaps = 15/143 (10%) Query: 13 RANCRGHGFTLIELVITLALVGIVAMAIVPLSELAVQRQKEQALRVALREIRTAIDAYKE 72 RA + GFTL+E+++ + ++G++A +VP ++ +Q + + A+D YK Sbjct: 2 RATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK- 60 Query: 73 ASDSGSVEHEAGASGYP---PSLAVLVEGVKDAKDPKG-GLLMFLRRVPRDPFFTGEAST 128 D+ YP L LVE +++R+P DP+ Sbjct: 61 -LDNHH---------YPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLV 110 Query: 129 PAADTWNLRAYGVPVDGGTGGDD 151 + DG G +D Sbjct: 111 NPGEHGAYDLLSAGPDGEMGTED 133
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 175 bits (444), Expect = 3e-48 Identities = 86/361 (23%), Positives = 154/361 (42%), Gaps = 53/361 (14%) Query: 279 KVRTFQLSNTDAKHIDTLLKNLLKIKE-----------------IVTDERANTVSIRATP 321 + L A + +L + + I + N + + A P Sbjct: 268 NTKVIYLKYAKASDLVEVLTGISSTMQSEKQAAKPVAALDKNIIIKAHGQTNALIVTAAP 327 Query: 322 ETIRVAERMIAAQDLPEPEVMLEVEVLEVSRDRLTDLGIDWPNS-------FSLGTPSSA 374 + + ER+IA D+ P+V++E + EV +LGI W N + G P S Sbjct: 328 DVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLGIQWANKNAGMTQFTNSGLPIST 387 Query: 375 STWGALHHLTVNQLTASGLSVTANLKL------------------TDTDANLLASPRIRT 416 + GA + +++S S ++ + T ++LA+P I T Sbjct: 388 AIAGANQYNKDGTVSSSLASALSSFNGIAAGFYQGNWAMLLTALSSSTKNDILATPSIVT 447 Query: 417 RNKEKAKILIGDKVPVISSSSVPSTSGPVYSQSIQYLDVGIKLEVEPQVYRDNDVGIKMS 476 + +A +G +VPV++ S S +++ VGIKL+V+PQ+ + V +++ Sbjct: 448 LDNMEATFNVGQEVPVLTGSQTTSGDNIF--NTVERKTVGIKLKVKPQINEGDSVLLEIE 505 Query: 477 LEVSNITQIISSSNAQTGLSSLAYQIGTRNASTTLRLKDGETQILGGLIQDEDRDAANKV 536 EVS++ A + S L TR + + + GET ++GGL+ D A+KV Sbjct: 506 QEVSSVAD-----AASSTSSDLGATFNTRTVNNAVLVGSGETVVVGGLLDKSVSDTADKV 560 Query: 537 PGLGQLPVLGRLFSNHNGDHKKTEIVLQITPHIVRPQLAADADTREIWSGTDSTVRTEQL 596 P LG +PV+G LF + + K ++L I P ++R + + R+ SG + Q Sbjct: 561 PLLGDIPVIGALFRSTSKKVSKRNLMLFIRPTVIRDR----DEYRQASSGQYTAFNDAQS 616 Query: 597 R 597 + Sbjct: 617 K 617 Score = 48.8 bits (116), Expect = 7e-08 Identities = 28/188 (14%), Positives = 69/188 (36%), Gaps = 21/188 (11%) Query: 185 AAASIMRKPVSLQ-----FRDANVRMVFEALSRTTGLSVIFDRDVR--VDLKTTIFVSNA 237 A+++ +P + + F+ +++ +S+ +VI D VR + +++ ++ Sbjct: 16 IFAALLFRPAAAEEFSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRSYDMLNEE 75 Query: 238 SLEDTVDMILLQNQLAKKVLNANTVFIYPATPAKQQEY-----------QDLKVRTFQLS 286 +L A +N + + + AK ++ R L+ Sbjct: 76 QYYQFFLSVLDVYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIGDEVVTRVVPLT 135 Query: 287 NTDAKHIDTLLKNLL---KIKEIVTDERANTVSIRATPETIRVAERMIAAQDLPEPEVML 343 N A+ + LL+ L + +V E +N + + I+ ++ D ++ Sbjct: 136 NVAARDLAPLLRQLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDNAGDRSVV 195 Query: 344 EVEVLEVS 351 V + S Sbjct: 196 TVPLSWAS 203
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 204 bits (520), Expect = 7e-64 Identities = 102/403 (25%), Positives = 181/403 (44%), Gaps = 6/403 (1%) Query: 3 YLLRVFDSGGLVQTVCIEGDTPAGATAAAHARGWKVIAVRAGGARGRHRIRGTVL----- 57 Y + D+ G E D+ A RG ++V + + Sbjct: 4 YHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLRRKI 63 Query: 58 GGTAFDVELFARELAALLDAGVSVIDALRTLGSNERREASAAVYRDLLRRLEEGHALSAA 117 + D+ L R+LA L+ A + + +AL + + + + + ++ EGH+L+ A Sbjct: 64 RLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLADA 123 Query: 118 LELADNVFPPVLVACVKASEQTGGLAASLKRYSQNSATLQALRARVVSASIYPAVLLAVG 177 ++ F + A V A E +G L A L R + + Q +R+R+ A IYP VL V Sbjct: 124 MKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLTVVA 183 Query: 178 GSVAVFLLAFVVPRFAGLLEHSGRELPMLSQWLMAWGAMVHAHGQGLAVGFAICVLAGIG 237 +V LL+ VVP+ H + LP+ ++ LM V G + + +A Sbjct: 184 IAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMAFRV 243 Query: 238 ALRRQATRSWATDRLLSLPGVGEHFRVYRQAQFFRTSAMLVDGGIPAVQAFDLACGLVS- 296 LR++ R RLL LP +G R A++ RT ++L +P +QA ++ ++S Sbjct: 244 MLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDVMSN 303 Query: 297 RADRAALASAMERIRNGGRMSDAFLGSGLADPITYRLLTVAEKTGGLGPVLDKIAAFQEA 356 R L+ A + +R G + A + L P+ ++ E++G L +L++ A Q+ Sbjct: 304 DYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADNQDR 363 Query: 357 HVSHAIDLASRLVEPAMMMVIGVVIGGIVVLMYLPIFQLASSV 399 S + LA L EP +++ + V+ IV+ + PI QL + + Sbjct: 364 EFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 160 bits (406), Expect = 1e-53 Identities = 57/140 (40%), Positives = 81/140 (57%), Gaps = 6/140 (4%) Query: 19 RCARREGGFTLLELLVVMVIIGLLAGLVAPQYFDQIGKSNLKIAKAQIESLGKALDQYRL 78 R ++ GFTLLE++VV+VIIG+LA LV P K++ + A + I +L ALD Y+L Sbjct: 2 RATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKL 61 Query: 79 DVGAYPSTEEGLDALNTRPQSQP---RWSGPYLKKAVPLDPWDRPYVYRSPGEHGEYDLY 135 D YP+T +GL++L P P ++ K +P DPW YV +PGEHG YDL Sbjct: 62 DNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDLL 121 Query: 136 SLGKSGQPGGTGENVAVTSW 155 S G G+ G + +T+W Sbjct: 122 SAGPDGEMGTEDD---ITNW 138
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 69.5 bits (170), Expect = 7e-16 Identities = 31/118 (26%), Positives = 53/118 (44%), Gaps = 2/118 (1%) Query: 6 RLLIAEDHHLLRCGLRSMLSALGEYDVVGEAKDGREACQLAISLAPDLVLTDLSMPGMNG 65 +L+A+D +R L LS G YDV + + + DLV+TD+ MP N Sbjct: 5 TILVADDDAAIRTVLNQALSRAG-YDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 66 IDMVATIKRRLPQIRVVVLTVYKSEEYVREALRVGVDGYVLKDASFEELVAALRAVMQ 123 D++ IK+ P + V+V++ + +A G Y+ K EL+ + + Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 35.6 bits (82), Expect = 3e-04 Identities = 63/388 (16%), Positives = 130/388 (33%), Gaps = 57/388 (14%) Query: 23 NSTVIFATGAIIGHMLAPSPALATVPVSIFVVGMAAATLPVGVVTRRYGRKTSALFGSVC 82 N V+ + I + PA + F++ + T G ++ + G K LFG Sbjct: 29 NEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFG--- 85 Query: 83 GVTVGLLAALALVIQSFSLFCVA--MLFGGAYAAVVLTYRFAAAECVPAEHRARAM---S 137 + + + V SF + + G AA A +P E+R +A Sbjct: 86 IIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIG 145 Query: 138 TVLAGGVAAGVLGPQLVTAT--------------------MNLWSPHAYAVTYLASAGTA 177 +++A G G ++ M L + G Sbjct: 146 SIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGII 205 Query: 178 VLSAIVLQGVRFEHQPPVSAH-----------AHGRPSSDIMRQPRFV--VAMLCGVVSY 224 ++S ++ + F +S H R +D P + + GV+ Sbjct: 206 LMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCG 265 Query: 225 MMMNFMMTSAPLAMELCGIPRVHANYGIEIHVIAMYAPS-------FFTGRLIARFGAPR 277 ++ + + + VH EI + ++ + + G L+ R G Sbjct: 266 GIIFGTVAGFVSMVPYM-MKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLY 324 Query: 278 VSLAGLALIALAATTGMTGVSVNHFWVALLLLGLGWNFGFLGASATVLTCH-----TPAE 332 V G+ ++++ T + +++ ++++ + G L + TV++ E Sbjct: 325 VLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFV---LGGLSFTKTVISTIVSSSLKQQE 381 Query: 333 GPRVQSIYDFVVFGAMVVGSFVSGGLLA 360 S+ +F F + G + GGLL+ Sbjct: 382 AGAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 30.7 bits (69), Expect = 0.010 Identities = 15/54 (27%), Positives = 22/54 (40%), Gaps = 9/54 (16%) Query: 128 LCGGSLGGYLAYLCAARMGAG-----PIAGVIATTLADPRSPL----VRRQFAR 172 + G G Y+ A R G AG+IA+ + SPL + +F R Sbjct: 279 VLGNVGKGISQYIIAQRAAQGLSTSAAAAGLIASAVTLAISPLSFLSIADKFKR 332
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 81.6 bits (201), Expect = 2e-20 Identities = 53/192 (27%), Positives = 86/192 (44%), Gaps = 1/192 (0%) Query: 3 NCFDFRGKTALITGASSGIGREFAYALAKRGAKLLLVARSRDKLHDLTAELRRDYACDAD 62 N GK A ITGA+ GIG A LA +GA + V + +KL + + L+ + A A+ Sbjct: 2 NAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAE-ARHAE 60 Query: 63 FLTVDLSAPDAIPTVAHLLKATGTVVDVLINNAGFATYGRFETIPWTRQRDEVLVNCMAA 122 D+ AI + ++ +D+L+N AG G ++ VN Sbjct: 61 AFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGV 120 Query: 123 IELTHLLLPGMQARSDGAVINVASTAAFQPDPYMAIYGATKAFLLSFSEAVWAENRHRGI 182 + + M R G+++ V S A P MA Y ++KA + F++ + E I Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNI 180 Query: 183 RVLALCPGATQT 194 R + PG+T+T Sbjct: 181 RCNIVSPGSTET 192
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 128 bits (322), Expect = 3e-34 Identities = 95/413 (23%), Positives = 175/413 (42%), Gaps = 17/413 (4%) Query: 21 RNTVALLAVCLAALMFGLEISSVPVILPTLEVALHGDFSGIQWIMNAYTIACTAVLMATG 80 R+ L+ +C+ + L + V LP + + + W+ A+ + + G Sbjct: 11 RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYG 70 Query: 81 TLADRYGRKRVFLYTIALFGVASLLCGLAWNT-PILIASRFLQGASGGAMLICLVAVLSH 139 L+D+ G KR+ L+ I + S++ + + +LI +RF+QG +G A LV V+ Sbjct: 71 KLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQG-AGAAAFPALVMVVVA 129 Query: 140 QFPEGAERGKAFGIWGIVFGIGLGFGPLIGGLIVAMSGWKWVFWVHVFIAALTFGLAIVG 199 ++ RGKAFG+ G + +G G GP IGG+I W ++ + + L + Sbjct: 130 RYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLL 189 Query: 200 VRESRDPHARRLDLAGIVTLSLTVLGLAYFVTQGADTGFGSASALRVIAATAVSFALFLI 259 +E R D+ GI+ +S+ ++ F T S S +I + +SF +F+ Sbjct: 190 KKEVR--IKGHFDIKGIILMSVGIVFFMLFTT--------SYSISFLIVSV-LSFLIFVK 238 Query: 260 VEMRAAHPMFDFSVFRVRNFSGALLGSVGMNFSFWPFIIYLPIYFQSALGQGAAAAG-VS 318 + P D + + F +L + + F+ +P + A G V Sbjct: 239 HIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVI 298 Query: 319 LLAYTLPTLVFPPIGERLALRYRPGIVIPAGLFTIGLGFFLMLIGSSIDQASWLTVLPGC 378 + T+ ++F IG L R P V+ G+ + + F + ++ SW + Sbjct: 299 IFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSF--LTASFLLETTSWFMTIIIV 356 Query: 379 LLAGAGLGITNTPVTNTTTGSVSPARAGMASGIDMSARMISLAINIALMGFLL 431 + G GL T T ++ + S+ AG + +S IA++G LL Sbjct: 357 FVLG-GLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLL 408
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 59.5 bits (144), Expect = 1e-11 Identities = 61/322 (18%), Positives = 127/322 (39%), Gaps = 23/322 (7%) Query: 61 WNTTLFIVASITGAAVAAQVIQHLGPRGAYLLGAMVFGGGSALCALA-PIMQVLLVGRVL 119 W T F++ G AV ++ LG + L G ++ GS + + +L++ R + Sbjct: 53 WVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFI 112 Query: 120 QGLGGGVLLSAPYVLMRSVLPEPLWPRALALLSGMWGIATLLGPAVGGIFAQYATWRLAF 179 QG G + V++ +P+ +A L+ + + +GPA+GG+ A Y Sbjct: 113 QGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHY-----IH 167 Query: 180 WSLVVLIALAAAAAVVVLKPAAPQAERPT-PVPTRQLVLLAVAVVAASWASVSDSPWLGA 238 WS ++LI + V L + R + ++L++V +V + S S Sbjct: 168 WSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLI 227 Query: 239 LGLIAAALTLLAIRRVEMRSSRRILPADAYTGRTALAALYGVSALLAVTVTCTEIFVPLF 298 + +++ + + IR+V + + + + ++ TV VP Sbjct: 228 VSVLSFLIFVKHIRKV----TDPFVDPGLGKNIPFMIGVL-CGGIIFGTVAGFVSMVPYM 282 Query: 299 LQRLHGQSPLIAGYIAATASAGWTLGAILSAALRAASVTR-----AIRLAPWACALGLLV 353 ++ +H S G + T+ I+ + V R + + ++ L Sbjct: 283 MKDVHQLSTAEIGSVIIFPG---TMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLT 339 Query: 354 LAMLVPIGAGSAWMTTLIIVAL 375 + L+ ++W T+IIV + Sbjct: 340 ASFLL---ETTSWFMTIIIVFV 358
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 37.6 bits (87), Expect = 4e-05 Identities = 39/178 (21%), Positives = 71/178 (39%), Gaps = 15/178 (8%) Query: 44 AQRVVSLAPHATELLFAAG----GGARIVGTVTYSDYPSAARDIPRVGDNRAVDLERIAA 99 R+V+L ELL A G G A + + P + VG +LE + Sbjct: 35 PNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTE 94 Query: 100 LKPDLVVV-WRHGNAQQQTDRLRALGIPLFFSEPRRLTDIPRAIEALGTLLDTRAGAHDA 158 +KP +V +G + + R+ A G FS+ ++ + R ++L + D A Sbjct: 95 MKPSFMVWSAGYGPSPEMLARI-APGRGFNFSDGKQPLAMAR--KSLTEMAD-LLNLQSA 150 Query: 159 AERFRRQADDL----RERYAGR--PPVTVFFQVWQQPLMTLNGQHVFSDMLALCGGRN 210 AE Q +D + R+ R P+ + + + ++ +F ++L G N Sbjct: 151 AETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYGIPN 208
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 33.6 bits (77), Expect = 0.001 Identities = 18/69 (26%), Positives = 25/69 (36%), Gaps = 15/69 (21%) Query: 149 QPRTLVYASTSGVYGDCGGAWVDETRPV-RPATPRAMRRVAAERRV-------------- 193 + + L+YAS+S VYG V P + A + A E Sbjct: 117 KIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGL 176 Query: 194 RWFGVGGGW 202 R+F V G W Sbjct: 177 RFFTVYGPW 185
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 43.4 bits (102), Expect = 6e-08 Identities = 19/73 (26%), Positives = 31/73 (42%), Gaps = 4/73 (5%) Query: 68 ELAGFARVISDHATFAYLCDVFVLPEWRGKGISHALMRLLREHPELQGLRRTVLVTTD-- 125 G ++ S+ +A + D+ V ++R KG+ AL+ E + +L T D Sbjct: 75 NCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDIN 134 Query: 126 --ADGLYRKHGFT 136 A Y KH F Sbjct: 135 ISACHFYAKHHFI 147
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.6 bits (69), Expect = 0.027 Identities = 30/124 (24%), Positives = 46/124 (37%), Gaps = 24/124 (19%) Query: 178 NALAKAGKIDPLIGREQEVERVVQVLCR--RRKNNPLLVGEAGVGKTAIAEGL---AWRI 232 + PL+GR ++ + +VL R + ++ GE+G GK +A L R Sbjct: 128 KLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRR 187 Query: 233 TK-------GEVPDILARSVVYSLDMGALLAGTKYR-GDFEQRLKGVLKSLKDNPNAILF 284 +P L S ++ + GA G FEQ G LF Sbjct: 188 NGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGT-----------LF 236 Query: 285 IDEI 288 +DEI Sbjct: 237 LDEI 240
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 29.9 bits (67), Expect = 0.042 Identities = 22/115 (19%), Positives = 39/115 (33%), Gaps = 9/115 (7%) Query: 411 KLGSALKRFNEYAEKNPGTIERMTDGFIGLSAVLIGGGVISMLNSSVRSFRLLTDVLFPA 470 LGS L K+ + L + G +S + S++ + +L++ Sbjct: 211 TLGSVL-----SNTKHLNGVGNKLQNLPNLDNIGAGLDTVSGILSAISASFILSNADADT 265 Query: 471 SRGLGGAAEATSALSKAIAMKEVGGALGIARIAAALGPVGLAGALIALGAGAIAL 525 E T+ + + K + + R A L A LI A A+ L Sbjct: 266 RTKAAAGVELTTKVLGNVG-KGISQYIIAQRAAQGLSTSAAAAGLI---ASAVTL 316
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 54.5 bits (131), Expect = 6e-10 Identities = 54/332 (16%), Positives = 121/332 (36%), Gaps = 26/332 (7%) Query: 45 VAGQHIQGGVHADPQAYLYAVTAYAVAAVVANLAIGRIAARIGYRMFSLIGIVLFGVGCV 104 V+ I + P + + TA+ + + G+++ ++G + L GI++ G V Sbjct: 35 VSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSV 94 Query: 105 VCAQSNS-IDMLVAGRAIQGLGAGGLFSASRILVQLTTDPDERIAPMLMFSVGLFGLTTI 163 + +S +L+ R IQG GA + ++V + R + + + Sbjct: 95 IGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGV 154 Query: 164 APWICAEVLEYSEWRVIFWLELLLAAAAWLAMFFLPPERHQPRTRAARRPHEAPPAEGRL 223 P I + Y W + + ++ M L E R +G Sbjct: 155 GPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKE--------VRI-------KGHF 199 Query: 224 DWIGVGAIAIGALAFLMGLSELRYNRLTATPAIPLLLLGGAAGLLLAVHRLRTHPDPWLD 283 D G+ +++G + F++ T + +I L++ + L+ H + DP++D Sbjct: 200 DIKGIILMSVGIVFFMLF---------TTSYSISFLIVSVLSFLIFVKHIRKVT-DPFVD 249 Query: 284 LTRLNGRRYLWGIGFYGIYYLMSGIWSYLFPAVSQGGLGFTFRTTTLFLMISGAVSMVVA 343 ++ G+ GI + + + P + + + ++ G +S+++ Sbjct: 250 PGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIF 309 Query: 344 MIFTIWLPFFFRKRRVIAIGFGIYAAAALLLA 375 L V+ IG + + L + Sbjct: 310 GYIGGILVDRRGPLYVLNIGVTFLSVSFLTAS 341
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 72.0 bits (176), Expect = 4e-17 Identities = 64/256 (25%), Positives = 108/256 (42%), Gaps = 19/256 (7%) Query: 3 KTIVITGGSRGIGRATAVLCARRGWSV-AIQYRGNRQAADETAGLVEQAGGRLLAVQGDV 61 K ITG ++GIG A A A +G + A+ Y + ++ E A DV Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAE--ARHAEAFPADV 66 Query: 62 SSEADVMALFEAAQDRFGALHGVVNNAGIVAPAQDVADMSAQRLRAIFETNVLGAFLVAR 121 A + + + G + +VN AG++ P + +S + A F N G F +R Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGL-IHSLSDEEWEATFSVNSTGVFNASR 125 Query: 122 EAARRLSTARGGAGGALVNVSSAAARLGSPHEYVD-YAASKGAVDTMTLGLARELGREGV 180 ++ + R G+ +V V S A G P + YA+SK A T L EL + Sbjct: 126 SVSKYMMDRRSGS---IVTVGSNPA--GVPRTSMAAYASSKAAAVMFTKCLGLELAEYNI 180 Query: 181 RVNAVRPGLIDTEIHAC--GGQPDRAQRLGA-------ATPMGRPGTAAEVAETIVWLLS 231 R N V PG +T++ + Q + P+ + +++A+ +++L+S Sbjct: 181 RCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVS 240 Query: 232 DAASYVTGALLDCSGG 247 A ++T L GG Sbjct: 241 GQAGHITMHNLCVDGG 256
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 58.5 bits (141), Expect = 9e-13 Identities = 22/132 (16%), Positives = 50/132 (37%), Gaps = 1/132 (0%) Query: 7 RSERSRKAAIQAALAILSRDGPGQLTFDAIARESGISKGGLMHQFPNKGAVLKALLEHQI 66 ++ +R+ + AL + S+ G + IA+ +G+++G + F +K + + E Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSE 67 Query: 67 EHFDKFTRGYLAEIGEDRPQAHLAAQIATLRESITTPHSVAF-AILAALIEDPELLALNR 125 + + Y A+ D I L ++T I+ E +A+ + Sbjct: 68 SNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQ 127 Query: 126 QMEADAIERIRA 137 Q + + Sbjct: 128 QAQRNLCLESYD 139
>PF06917#Periplasmic pectate lyase Length = 555 Score = 30.3 bits (68), Expect = 0.011 Identities = 28/145 (19%), Positives = 45/145 (31%), Gaps = 13/145 (8%) Query: 124 ADPAIRAEIDAEAARDGWPALHAKLAQVDPVTAARLHATDAQRIQRALELYRLTGQPMSA 183 D + I R L+ K + + AA+ + +EL P Sbjct: 408 EDEELLDLIGVLLLRWQLAELN-KTQRRATLMAAQRPIASPYLLLALVELAEHCQCPTLF 466 Query: 184 LLAREAGAAAFHRHEAAAAYLSIALEPADRAVLHARIAQRFDAMLAGGLLDEVEALRRRG 243 LA + G F RH ++ R D +A LL + A + Sbjct: 467 TLAWQIGDDLFKRHYHRGLFVES----------AQHRYFRIDNPIALALLTLIAAK--QD 514 Query: 244 DLSPVLPSIRCVGYRQAWAYLDGEI 268 L+ + I GY ++GE Sbjct: 515 KLAAIPQFITNGGYIHGDYRVNGES 539
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 44.6 bits (105), Expect = 2e-08 Identities = 15/56 (26%), Positives = 21/56 (37%) Query: 89 LYLEDLFVEPAWRGHGIGKALLVHVARLARERDCGRFEWSVLDWNAPSIAFYEAMG 144 +ED+ V +R G+G ALL A+E D N + FY Sbjct: 90 ALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHH 145
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 82.0 bits (202), Expect = 1e-20 Identities = 64/258 (24%), Positives = 107/258 (41%), Gaps = 16/258 (6%) Query: 4 KIALITGASRGLGRNMALHLAKRGVHIIGTYRSGAEQAQTLKQEIEALGGKATMLALDVT 63 KIA ITGA++G+G +A LA +G HI E+ + + ++A A DV Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAA-VDYNPEKLEKVVSSLKAEARHAEAFPADVR 67 Query: 64 ETAGYPAFTSAVTDTLKNDFGRERFDFLINNAGNGLFAKFVDATEEQFASLIATHLRGPI 123 ++A T+ + + D L+N AG ++E++ + + + G Sbjct: 68 DSAAIDEITARIEREM------GPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVF 121 Query: 124 FLTQKLLPLL--ENGGRILNVSSGFVRFTMPGYSVYAAVKAALEVLTRYMAVELGSRQIR 181 ++ + + G I+ V S + YA+ KAA + T+ + +EL IR Sbjct: 122 NASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIR 181 Query: 182 VNAIAPGAIATDF-------GGGAVRDNKDVNAYVAQGIALGRVGLPDDIGGAVAAILSD 234 N ++PG+ TD GA + K GI L ++ P DI AV ++S Sbjct: 182 CNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSG 241 Query: 235 DMGWANGTTFDISGGQLL 252 G + GG L Sbjct: 242 QAGHITMHNLCVDGGATL 259
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.7 bits (66), Expect = 0.012 Identities = 14/36 (38%), Positives = 21/36 (58%) Query: 35 NAVVITGANGVGKTTLLRMLAGLVPAAEACVDFGRG 70 +VV+ G G+GK+TL+ L GL ++ D G G Sbjct: 597 YSVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTG 632
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 137 bits (348), Expect = 5e-38 Identities = 81/386 (20%), Positives = 143/386 (37%), Gaps = 79/386 (20%) Query: 5 IGIDLGTTNSCVSIMEG----NTPKVIE-NAEGARTTPSIIAYMEDGEILVGAPAKRQAV 59 + IDLGT N+ + + N P V+ + A + S+ A VG AK+ Sbjct: 13 LSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAA--------VGHDAKQMLG 64 Query: 60 TNPRNTLYAVKRLIGRKFEEKEVQKDIGLMPYTISKADNGDAWVEVRDKKMAPPQISAEV 119 P N + A++ + +D +A ++ ++ Sbjct: 65 RTPGN-IAAIRPM---------------------------------KDGVIADFFVTEKM 90 Query: 120 LRK-MKKTAEDYLGEEVTEAVITVPAYFNDSQRQATKDAGRIAGLDVKRIINEPTAAALA 178 L+ +K+ + ++ VP +R+A +++ + AG +I EP AAA+ Sbjct: 91 LQHFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIG 150 Query: 179 FGLDKNEKGDRKIAVYDLGGGTFDISIIEIADVDGEKQFEVLSTNGDTFLGGEDFDQRII 238 GL +E V D+GGGT ++++I + V + +GG+ FD+ II Sbjct: 151 AGLPVSE--ATGSMVVDIGGGTTEVAVISLNGV---------VYSSSVRIGGDRFDEAII 199 Query: 239 DYIIGEFKKESGVDLSKDVLALQRLKDAAEKAKIELSST----QQTEINLPYITADASGP 294 +Y+ + G + AE+ K E+ S + EI + P Sbjct: 200 NYVRRNYGSLIG-------------EATAERIKHEIGSAYPGDEVREIEVRGRNLAEGVP 246 Query: 295 KHLNLKITRAKLEALVEDLIARTIEPCRTAIKDAGVKVSDIHD--VILVGGMTRMPKVQE 352 + L + LEAL E L + SDI + ++L GG + + Sbjct: 247 RGFTLN-SNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNLDR 305 Query: 353 KVKEFFGKEARKDVNPDEAVAVGAAI 378 + E G +P VA G Sbjct: 306 LLMEETGIPVVVAEDPLTCVARGGGK 331
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 30.9 bits (70), Expect = 0.011 Identities = 17/62 (27%), Positives = 25/62 (40%), Gaps = 9/62 (14%) Query: 25 YGEIRDGAIAVRDGRIAWLGARA--------DLPAGARAEREHDGGGAWLTPGLIDCHTH 76 + I I ++DGRIA +G + G E G G +T G +D H H Sbjct: 80 HWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTE-VIAGEGKIVTAGGMDSHIH 138 Query: 77 LV 78 + Sbjct: 139 FI 140
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 30.6 bits (69), Expect = 0.005 Identities = 15/68 (22%), Positives = 25/68 (36%), Gaps = 9/68 (13%) Query: 49 DIVFERETALNIGVQDYPALP----PDEMARHAD-VAVVLGGDGTLLGIGRHLAGA---- 99 F E A N+G+ P P + + + L GDG + + + G Sbjct: 18 ANAFADEFADNLGLTLLPVEPSTQVNAASSHTKPPLVIFLSGDGGWATLDKAVGGILQQQ 77 Query: 100 SVPVIGVN 107 PV+G + Sbjct: 78 GWPVVGWS 85
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 33.9 bits (77), Expect = 0.002 Identities = 47/227 (20%), Positives = 90/227 (39%), Gaps = 26/227 (11%) Query: 163 RAWQAVVRLREAAEQQSREAQLERERVEWQVSELQKLAPQPGEWEEVQAEHHRLSHAASL 222 +A + + EAAE+ +EA+ R+ +E + +E ++ Q E + LS A Sbjct: 134 KAEEKARKEAEAAEKAFQEAEQRRKEIEREKAETER---QLKLAEAEEKRLAALSEEAKA 190 Query: 223 IEGTRAALDT-------LSEADSAVLTQLGAAVHGLQALAEIDPALADVLAALEPAQVQV 275 +E + L + + ++L +++H A + LA L A + Sbjct: 191 VEIAQKKLSAAQSEVVKMDGEIKTLNSRLSSSIHARDAEMK---TLAGKRNELAQASAKY 247 Query: 276 QEAVHSLARYADRAELDPDR----LAEVDARLQALHTM--ARKYRVAPET----LPAELT 325 +E + + + RA DP + R+ A +K A ET + A++T Sbjct: 248 KELDELVKKLSPRAN-DPLQNRPFFEATRRRVGAGKIREEKQKQVTASETRINRINADIT 306 Query: 326 QRQAQLAALQAASDLDALQAQEAQTHAAYLQAAQALSRGRAKAAREL 372 Q Q A Q +++ +A A+ + +A L + K A + Sbjct: 307 --QIQKAISQVSNNRNAGIARVHEAEENLKKAQNNLLNSQIKDAVDA 351
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 115 bits (289), Expect = 1e-30 Identities = 82/386 (21%), Positives = 131/386 (33%), Gaps = 87/386 (22%) Query: 130 PNDPLFSTQNNLQSPTVVAGGINVASAWDITLGSSSLVVAVVDTGY-TDHPDLSGKILPG 188 N + I + W+ T G + VAV+DTG DHPDL +I+ G Sbjct: 11 QVIKQEQQVNEIPRG---VEMIQAPAVWNQTRGRG-VKVAVLDTGCDADHPDLKARIIGG 66 Query: 189 YNFISDPARAGNSTGRGSDAHDTGDGVTSADVSAISGCTSSDIGNSTWHGTEVMSVLAAG 248 NF D D D HGT V A Sbjct: 67 RNFTDD---------DEGDPEIFKDY--------------------NGHGTHVAGT-IAA 96 Query: 249 TNNALDIAGVGWNTRIVPVRTSGKCG-ALLSDTVDGMLWAGGISVSGVPANPNPARVINV 307 T N + GV ++ ++ K G + G+ + A +I++ Sbjct: 97 TENENGVVGVAPEADLLIIKVLNKQGSGQYDWIIQGIYY----------AIEQKVDIISM 146 Query: 308 SLGSVGSCSAAEQDAINRLAALGTVVVAAAGNEGSAVDA------PANCSGAIAVTAHVD 361 SLG +A+ + A +V+ AAGNEG D P + I+V A Sbjct: 147 SLGGPED-VPELHEAVKKAVASQILVMCAAGNEGDGDDRTDELGYPGCYNEVISVGAINF 205 Query: 362 SGENASYANVGSQVALSAPGGGCANSQATSSGCTGPVSVIQADSNDGQYSLGNSVVKSVA 421 + ++N ++V L APG I + G+Y+ + + Sbjct: 206 DRHASEFSNSNNEVDLVAPGED-----------------ILSTVPGGKYA-------TFS 241 Query: 422 GTSFSTPEVAGTIALMLS-----VQSQLSNAQILAGLQQTARAHPSGTFCATRGGCGAGL 476 GTS +TP VAG +AL+ + L+ ++ A L + + G GL Sbjct: 242 GTSMATPHVAGALALIKQLANASFERDLTEPELYAQLIKRTIP-----LGNSPKMEGNGL 296 Query: 477 LDTAGAVRYAQTTTPAGIGSGSSSSS 502 L ++ + S++S Sbjct: 297 LYLTAVEELSRIFDTQRVAGILSTAS 322
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 130 bits (328), Expect = 2e-35 Identities = 81/359 (22%), Positives = 118/359 (32%), Gaps = 94/359 (26%) Query: 172 NLTTAWDTTKGSNTVTVTVIDTGLLAGHADLSGATIQPGYDFVSSTAMTGTPDPVTNLSI 231 W+ T+G V V V+DTG A H DL I G +F Sbjct: 30 QAPAVWNQTRGRG-VKVAVLDTGCDADHPDLKA-RIIGGRNFTD---------------- 71 Query: 232 PSGFVENDATAGRDSDPTDPGDWITTSDATNYPSFCGTSVTDSSWHGTFVTGLIAAQHNA 291 + DP D + HGT V G IAA N Sbjct: 72 -----------DDEGDPEIF--------------------KDYNGHGTHVAGTIAATENE 100 Query: 292 IGVAGVAPGVSVQMTRAIGKCG-GASSDILDALTWAAGGTVPGVTTNATPAKVINMSLGG 350 GV GVAP + + + + K G G I+ + +A +I+MSLGG Sbjct: 101 NGVVGVAPEADLLIIKVLNKQGSGQYDWIIQGIYYAI----------EQKVDIISMSLGG 150 Query: 351 STACTTAQQSAITAARSLGATIVVATGNEFQNA----AIDAPASCSGTIAVTAHTLEGDI 406 + A+ A + ++ A GNE + P + I+V A + Sbjct: 151 PEDVPELHE-AVKKAVASQILVMCAAGNEGDGDDRTDELGYPGCYNEVISVGAINFDRHA 209 Query: 407 ANYANVGTGTTLSAPGGGNGSTATGLGALVPSTSNAGTTTASTDTYVGEEGTSMSTPQVA 466 + ++N L APG +T Y GTSM+TP VA Sbjct: 210 SEFSNSNNEVDLVAPGEDI------------------LSTVPGGKYATFSGTSMATPHVA 251 Query: 467 GVAALMLSVNAA-----LTPDQIKTILQTSSRPFPPDTFCTTHAGVCGAGMLDAGSAIA 520 G AL+ + A LT ++ L + P + G G+L + Sbjct: 252 GALALIKQLANASFERDLTEPELYAQLIKRTIPLGNSPK------MEGNGLLYLTAVEE 304
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 29.8 bits (67), Expect = 0.005 Identities = 16/60 (26%), Positives = 27/60 (45%), Gaps = 5/60 (8%) Query: 6 RRADRLFQIAQILRGRRLTTAAMLADRL-----GVSERTVYRDIRDLSVSGVPIEGEAGI 60 + R +I +I+ + T L D L V++ TV RDI++L + VP + Sbjct: 2 NKGQRHIKIREIITANEIETQDELVDILKKDGYNVTQATVSRDIKELHLVKVPTNNGSYK 61
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 152 bits (386), Expect = 3e-50 Identities = 46/150 (30%), Positives = 76/150 (50%), Gaps = 1/150 (0%) Query: 18 IAEKDRKK-IAEGLSRLLADTYSLYLKTHNFHWNVTGPMFNTLHLMFETQYNELWTAVDS 76 K + + L+ L++ + LY K H FHW V GP F TLH FE Y+ VD+ Sbjct: 4 ENAKTNQTLVENSLNTQLSNWFLLYSKLHRFHWYVKGPHFFTLHEKFEELYDHAAETVDT 63 Query: 77 VAERIRALGYPAPGSYSEFARLSSIPEAKGVPAAEDMIRELVAGHESVTRTARSLFPDVD 136 +AER+ A+G + E+ +SI + +A +M++ LV ++ ++ ++ + + Sbjct: 64 IAERLLAIGGQPVATVKEYTEHASITDGGNETSASEMVQALVNDYKQISSESKFVIGLAE 123 Query: 137 KAADEPTADLLTQRMDIHEKTAWMLRSLLA 166 + D TADL ++ EK WML S L Sbjct: 124 ENQDNATADLFVGLIEEVEKQVWMLSSYLG 153
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 344 bits (884), Expect = e-108 Identities = 150/800 (18%), Positives = 260/800 (32%), Gaps = 92/800 (11%) Query: 27 LNQQGLDDTVLLLKTKGGELYA----SAEDLKRWRLRQPEATP--LAHNNEVFYPLKAIT 80 LN + + T E + L L + L ++ I Sbjct: 84 LNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLTSMIH 143 Query: 81 GLSYQLDETLLTVAVTAPAQAFLPNAFDEANKPVALSLKPGFGGFLNYDLLAEHATGQT- 139 + QLD + +T P QAF+ N P L G LNY+ + Sbjct: 144 DATAQLDVGQQRLNLTIP-QAFMSNRARGYIPP-ELWDPGINAGLLNYNFSGNSVQNRIG 201 Query: 140 RSSGLFEAGVFNGLGVGVASF----------VANSGDTEHRLIRLETTWTKDLPDHLSSV 189 +S + +GL +G +S ++++ + T +D+ S + Sbjct: 202 GNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRL 261 Query: 190 RLGDSISRAGAWGRSVRFGGIQYSTNFAVQPGFVALPLQSIGGQAALPSTVDVYVNNVLS 249 LGD ++ + + F G Q +++ + P I G A + V + N Sbjct: 262 TLGDGYTQGDIFD-GINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDI 320 Query: 250 SRKDVAPGPFSITNVPVVTGQGDVRVVVRDLLGREQVISVPFYASASLLAKGLHDFSYEA 309 V PGPF+I ++ GD++V +++ G Q+ +VP+ + L +G +S A Sbjct: 321 YNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITA 380 Query: 310 GAERRNFGTDSNDYGRAFAAATHRLGFTDWLTGEVHAESQLERQTVGLGTVMLAPSVGVF 369 G R F +T G T + + G ++G Sbjct: 381 GEYRSGNAQQEKPR---FFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGAL 437 Query: 370 SAAAAASRGRQGSGGLV---SVGFERQASPVSVGVHAQLASPRF---------------- 410 S + SV F S G + QL R+ Sbjct: 438 SVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRM 497 Query: 411 ----------------TQLGLELDMPAPRLLSSVNVGMALPGGGSLGLAYVYLD--NRDG 452 R + V L +L L+ + Sbjct: 498 NGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSN 557 Query: 453 HPTQLASASYGTQLGRFGF-ISLALSKTLHQPGGLM-VGLNWTLPLGERTTTSINMTQQQ 510 Q A T + +S +L+K Q G + LN +P + + Sbjct: 558 VDEQF-QAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRH 616 Query: 511 ------------GRTEVQAQVQQGLPPGDGFGYSVRAS--------QLGAWDAALNAQNR 550 GR A V L + YSV+ A LN + Sbjct: 617 ASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGG 676 Query: 551 VGTYLLEAAGDRGQTGVRMGASGGIAILD-GLHLSRRISDSFAVVKVPDFPNVRIYADNQ 609 G + + + G SGG+ G+ L + ++D+ +VK P + ++ +NQ Sbjct: 677 YGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKV--ENQ 734 Query: 610 LVAKTNASGEALIPRLRAYEKNAISLEQLDLPFDAKVGTLSLDAVPYYRSGMVLDFPVTH 669 +T+ G A++P Y +N ++L+ L + + + VP + + +F Sbjct: 735 TGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARV 794 Query: 670 AHDALMTLKLENGSDLPAGATVQISGQKEAFPVGNDGVVYLTGLAAQNRLQANW---RGQ 726 LMTL N LP GA V + + V ++G VYL+G+ ++Q W Sbjct: 795 GIKLLMTLT-HNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENA 853 Query: 727 SC--DISVPFTPGADPLPDL 744 C + +P L L Sbjct: 854 HCVANYQLPPESQQQLLTQL 873
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 31.7 bits (72), Expect = 0.004 Identities = 37/229 (16%), Positives = 70/229 (30%), Gaps = 59/229 (25%) Query: 11 ALIDVARMTRNIERMQQRLDALGVRFRPHVKTTKCEPVVRAQLAAGAQGITVSTLKEAEQ 70 A +D+ + +N+ ++Q H + V + + A A G + + A Sbjct: 7 ASLDLQALKQNLSIVRQAA--------THAR-------VWSVVKANAYGHGIERIWSA-- 49 Query: 71 FFSAGICDIVYAVGMAPARLPQALALRRRGCDLKIV----ADSVTCAQAIAAF------- 119 I G A L +A+ LR RG I+ + Sbjct: 50 --------IGATDGFALLNLEEAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVH 101 Query: 120 GGEHGEAF---------DVWIEVDVDGHRSGIAPDDDRLITVGRVLAEGGMRLGGVLAHA 170 +A D++++V+ +R G P D L ++ A + +++H Sbjct: 102 SNWQLKALQNARLKAPLDIYLKVNSGMNRLGFQP-DRVLTVWQQLRAMANVGEMTLMSH- 159 Query: 171 GSSYEYHAHDALVRIAELERSGCVRAAERLRAAGLPCETVSIGSTPTAL 219 + A A GL C S+ ++ L Sbjct: 160 -----------FAEAEHPDGISGAMARIEQAAEGLECR-RSLSNSAATL 196
>PilS_PF08805#PilS N terminal Length = 185 Score = 31.1 bits (70), Expect = 0.006 Identities = 12/52 (23%), Positives = 17/52 (32%), Gaps = 6/52 (11%) Query: 430 QEVNRLLNQFEQMQTMMKKLKGGG------MMKMMRAMGGLKGGMKGLLPGG 475 + + N + MK LK G +K + A G L M G Sbjct: 58 IQSSNEQNNVLTVIANMKSLKFQGRYTDSNYIKTLYAQGLLPSDMIADTTGA 109
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 37.1 bits (86), Expect = 8e-05 Identities = 32/130 (24%), Positives = 47/130 (36%), Gaps = 10/130 (7%) Query: 130 GLGVVPIINENDTVVTDEIKFGDNDTLGALVTNLIEGDALIILTDQRGLYTADPRKHPDA 189 G G VP+I E+ + E D D G + + D +ILTD G Sbjct: 193 GGGGVPVILEDGEIKGVEAVI-DKDLAGEKLAEEVNADIFMILTDVNGAAL-YYGT-EKE 249 Query: 190 RFVDEAQAGAPELEAMAGGAGSSIGKGGMLTKIVAAKRAAKSGAHTVIASGREADVLARL 249 +++ E + EL G M K++AA R + G I + L Sbjct: 250 QWLREVKVE--ELRKYY--EEGHFKAGSMGPKVLAAIRFIEWGGERAII-AHLEKAVEAL 304 Query: 250 AGGEAIGTQL 259 G GTQ+ Sbjct: 305 EG--KTGTQV 312
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 32.9 bits (75), Expect = 0.003 Identities = 27/116 (23%), Positives = 46/116 (39%), Gaps = 11/116 (9%) Query: 292 LLCLAVVFMALATPLSAWASDRWGRKPVLLTGILAAILSGFTMAPLLGSGSTPLVALFLI 351 LL L + P+ SDR+GR+PVLL + A + MA + P + + I Sbjct: 48 LLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMA------TAPFLWVLYI 101 Query: 352 LELF--LMGVTFAPMGALLPELFPTH--VRYTG-AGVSYNLGGILGASIAPYIAQV 402 + + G T A GA + ++ R+ G + G + G + + Sbjct: 102 GRIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGF 157
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 601 bits (1550), Expect = 0.0 Identities = 213/564 (37%), Positives = 314/564 (55%), Gaps = 10/564 (1%) Query: 273 AIGGIGASPGLAIGTVHV-MQPGVSAIPDHPVPLATGGDLLDRALADTRAELAALARDTA 331 I GI AS G+AI + ++P V ++T + L AL ++ EL A+ T Sbjct: 4 KITGIAASSGVAIAKAFIHLEPNVDIEKTSITDVSTEIEKLTAALEKSKEELRAIKDQTE 63 Query: 332 ARLGEAEAGIFKAQAELLGDTDLMT-LTCQAMVEGHGVAWSWHHAVERLAERLAALGNPL 390 A +G +A IF A +L D +L+ + + E ++ + ++ N Sbjct: 64 ASMGADKAEIFAAHLLVLDDPELVDGIKGKIENEQMNAEYALKEVSDMFVSMFESMDNEY 123 Query: 391 LAARAADLRDVGRRVLGHLDPALRGTAQALPDGPCILVAQDLSPSDTAALDTRRIAGIVT 450 + RAAD+RDV +RVLGHL G+ + + +++A+DL+PSDTA L+ + + G T Sbjct: 124 MKERAADIRDVSKRVLGHLIGVETGSLATIAE-ETVIIAEDLTPSDTAQLNKQFVKGFAT 182 Query: 451 AQGGPTSHTAILTRTLGIPAVVAAGPAVLDVASGTQAIVDGSGGQLYLDPDAAAVAGAEA 510 GG TSH+AI++R+L IPAVV + G IVDG G + ++P V E Sbjct: 183 DIGGRTSHSAIMSRSLEIPAVVGTKEVTEKIQHGDMVIVDGIEGIVIVNPTEEEVKAYEE 242 Query: 511 WLREDAARAQREQAERGLPARTRDGHAVEIAANVNLPAQAIEAVTLGAEGVGLMRTEFLF 570 + Q G P+ T+DG VE+AAN+ P + G EG+GL RTEFL+ Sbjct: 243 KRAAFEKQKQEWAKLVGEPSTTKDGAHVELAANIGTPKDVDGVLANGGEGIGLYRTEFLY 302 Query: 571 LERDHAPDEDAQHEVYAAMLGALGGRPLIVRTLDIGGDKQVPHLNLPKEENPFLGVRGAR 630 ++RD P E+ Q E Y ++ + G+P+++RTLDIGGDK++ +L LPKE NPFLG R R Sbjct: 303 MDRDQLPTEEEQFEAYKEVVQRMDGKPVVIRTLDIGGDKELSYLQLPKELNPFLGFRAIR 362 Query: 631 LLLRRPDLMEPQLRALYRAASGGGPLSIMFPMITSLGEVIALRAACERIRAELDAPAVP- 689 L L + D+ QLRAL R AS G L +MFPMI +L E+ +A + + +L + V Sbjct: 363 LCLEKQDIFRTQLRALLR-ASTYGNLKVMFPMIATLEELRQAKAIMQEEKDKLLSEGVDV 421 Query: 690 -----LGIMVEVPAAALLADQLAEHVDFFSIGTNDLTQYTLAIDRQHPDLAAEADSLHPA 744 +GIMVE+P+ A+ A+ A+ VDFFSIGTNDL QYT+A DR + ++ HPA Sbjct: 422 SDSIEVGIMVEIPSTAVAANLFAKEVDFFSIGTNDLIQYTMAADRMNERVSYLYQPYHPA 481 Query: 745 VLRLIQLTVQGAARHGRWVGVCGGLAGDPFGALLLTGLGVHELSMSPRDIPAVKARLRDA 804 +LRL+ + ++ A G+WVG+CG +AGD LL GLG+ E SMS I +++L Sbjct: 482 ILRLVDMVIKAAHSEGKWVGMCGEMAGDEVAIPLLLGLGLDEFSMSATSILPARSQLLKL 541 Query: 805 HVRQLTELAGQALACASAEDVRAL 828 +L A +AL +AE+V L Sbjct: 542 SKEELKPFAQKALMLDTAEEVEQL 565
>STREPTOPAIN#Streptopain (C10) cysteine protease family signature. Length = 398 Score = 31.2 bits (70), Expect = 0.004 Identities = 21/78 (26%), Positives = 36/78 (46%), Gaps = 12/78 (15%) Query: 3 KLLAIFALAGFMIAAPVFANEGGVRLDPAPNQS-----EDLSALQRGAKL-------FVN 50 +LL++ AL GF++A PVFA++ R + S + +A++ GA+ VN Sbjct: 9 RLLSLLALGGFVLANPVFADQNFARNEKEAKDSAITFIQKSAAIKAGARSAEDIKLDKVN 68 Query: 51 YCLNCHGASAMRYNRLRD 68 G++ YN Sbjct: 69 LGGELSGSNMYVYNISTG 86
>MECHCHANNEL#Bacterial mechano-sensitive ion channel signature. Length = 136 Score = 118 bits (296), Expect = 3e-37 Identities = 62/143 (43%), Positives = 89/143 (62%), Gaps = 13/143 (9%) Query: 1 MALMQDFKKFAMRGNVIDLAVGVIIGAAFGKIVDSLVNDLIMPLVARIVGKLDFSNLFIQ 60 M+++++F++FAMRGNV+DLAVGVIIGAAFGKIV SLV D+IMP + ++G +DF + Sbjct: 1 MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60 Query: 61 LADAPAGVPQTLADLKKAGVPVFAYGNFITVAVNFLILAFIVFLMVRAITRVIDTNPPPA 120 L DA +P V YG FI +FLI+AF +F+ ++ I ++ PA Sbjct: 61 LRDAQGDIPAV----------VMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPA 110 Query: 121 DTP---ENTLLLRDIRDSLKSKN 140 P + +LL +IRD LK +N Sbjct: 111 AAPAPTKEEVLLTEIRDLLKEQN 133
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 53.3 bits (128), Expect = 8e-10 Identities = 71/376 (18%), Positives = 125/376 (33%), Gaps = 54/376 (14%) Query: 63 MPLLGHDFGLSPAQTSLVLSATTMLLAFAILFAGLLSESIHRKTLMGVSLVLSSALTVAA 122 +P + +DF PA T+ V +A + + G LS+ + K L+ ++++ +V Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 123 AVLPGWQGLL-ATRAVLGVVLGGVPAVAMAYLAEEVHPQGLGMAMGLYVGGTAFGGMAGR 181 V + LL R + G PA+ M +A + + G A GL A G G Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 182 VLTGMVADYAGW---------------------------RVAMGFIGALCLLAALAFAWL 214 + GM+A Y W + G + + + F L Sbjct: 157 AIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFML 216 Query: 215 LPPSRRFA------------PRRGVALADLFDTLAEHLREPGLRALFAMAFLLMG---GF 259 S + + + D F P + + ++ G GF Sbjct: 217 FTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVL-CGGIIFGTVAGF 275 Query: 260 VTIYNYASYRLLSAPYALSHSAVGAIFM--VYLLGIGASTWFGRLADRHGRGRVLLAGTA 317 V++ Y ++ + LS + +G++ + + I G L DR G VL G Sbjct: 276 VSMVPY----MMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVT 331 Query: 318 AMSAGVLMTLAMPLG--LVIGGIALLTFGFFGAHA-VASGWVGRRARRAK-GQAAALYLL 373 +S L + + I + G V S V ++ + G +L Sbjct: 332 FLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNF 391 Query: 374 AYYLGSSIAGTAGGKL 389 +L G L Sbjct: 392 TSFLSEGTGIAIVGGL 407
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 47.1 bits (112), Expect = 2e-08 Identities = 21/102 (20%), Positives = 41/102 (40%), Gaps = 9/102 (8%) Query: 1 MQAPVRFAIADDHPGVVAAVRHLVCRVEGFEVVGEATSADGLLALLGRVHCDVVITDYAM 60 M +ADD + + + R G++V ++A L + D+V+TD M Sbjct: 1 MTGA-TILVADDDAAIRTVLNQALSR-AGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVM 57 Query: 61 PASRHGDGIVLLEFLLRRHPGVRVVVLTMLETHAVVDRMLRA 102 P + LL + + P + V+V++ ++A Sbjct: 58 P---DENAFDLLPRIKKARPDLPVLVMS---AQNTFMTAIKA 93
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 59.5 bits (144), Expect = 4e-11 Identities = 31/119 (26%), Positives = 51/119 (42%), Gaps = 6/119 (5%) Query: 736 HILVAEDHPINRELITRQLRLLGYRVTLAEDGAAALQRLCETRFDALLTDCCMPRLDGFD 795 ILVA+D R ++ + L GY V + + A + + D ++TD MP + FD Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 796 LARQIRQREQQAPGGRRLPILAITATTLAEEHARCRTVGMDGYVLKPTTLATLQDALSR 854 L +I++ LP+L ++A + G Y+ KP L L + R Sbjct: 65 LLPRIKKARP------DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 84.5 bits (209), Expect = 5e-21 Identities = 39/122 (31%), Positives = 58/122 (47%), Gaps = 1/122 (0%) Query: 10 PTVLVIDDEPHIRRFVRAALEAEGCEVFEADRVARGLIEAGTRQPDAVILDLGLPDGDGM 69 T+LV DD+ IR + AL G +V A D V+ D+ +PD + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 70 SLIRDLRT-WTEVPVLVLSARVDERDKIDALDAGADDYLTKPFGVGELIARLRVLLRRHA 128 L+ ++ ++PVLV+SA+ I A + GA DYL KPF + ELI + L Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 129 KR 130 +R Sbjct: 124 RR 125
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 66.4 bits (162), Expect = 3e-14 Identities = 56/234 (23%), Positives = 86/234 (36%), Gaps = 25/234 (10%) Query: 1 MKKSAILVAVGALFAGSAYAQSSVTLYGIVDATIHYTTNANQAG---NSLLRMDNGAVSN 57 MKKS I + + AL A + VTLYG + A + + + G S+ Sbjct: 1 MKKSLIALTLAALPVA---AMADVTLYGTIKAGVETSRSVAHNGAQAASVETGTGIVDLG 57 Query: 58 SRWGLKGSEDLGGGNKALFVLESGFDPDTGRVNSGGLFNRQSFVGLSNKDYGTLTMGRQY 117 S+ G KG EDLG G KA++ +E G NRQSF+GL +G L +GR Sbjct: 58 SKIGFKGQEDLGNGLKAIWQVEQKASIAGT---DSGWGNRQSFIGLK-GGFGKLRVGRLN 113 Query: 118 NFGFTMGGNFDPLGVGNYDENSWLYYGVTGLRVSNML---KYEG-KWNGLYVGLGYGFGE 173 D + +D S L +Y+ ++ GL + Y + Sbjct: 114 ------SVLKDTGDINPWDSKSDYLGVNKIAEPEARLISVRYDSPEFAGLSGSVQYALND 167 Query: 174 QAGSTANNRYMGGAVSYEFGPALIGAFYQQ----QQDSTAAGNKQKVWGIGGNY 223 AG + Y +Y+ G + Q K ++ + Y Sbjct: 168 NAGRHNSESY-HAGFNYKNGGFFVQYGGAYKRHHQVQENVNIEKYQIHRLVSGY 220
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 201 bits (512), Expect = 1e-69 Identities = 67/135 (49%), Positives = 89/135 (65%), Gaps = 3/135 (2%) Query: 21 RGFTLIEIMVVVVILGILAALVVPKIMSRPDEARIIAAKQDIASISQALKLYRLDNGRYP 80 RGFTL+EIMVV+VI+G+LA+LVVP +M ++A A DI ++ AL +Y+LDN YP Sbjct: 8 RGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDNHHYP 67 Query: 81 TTEQGLAALVTKPTTEPVPNNWKGGGYLERLPKDPWGHPYQYLNPGVRGEVDIFSYGADG 140 TT QGL +LV PT P+ N+ GY++RLP DPWG+ Y +NPG G D+ S G DG Sbjct: 68 TTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDLLSAGPDG 127 Query: 141 QPGGTANDADIGNWD 155 + G + DI NW Sbjct: 128 EMGT---EDDITNWG 139
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 52.6 bits (126), Expect = 3e-11 Identities = 23/75 (30%), Positives = 39/75 (52%), Gaps = 6/75 (8%) Query: 14 RRGFTLLELLVVVVIIGIVLGVVAVNATPNPRSQLADDAQKLARL---IELAQEEAQLTA 70 +RGFTLLE++++++++G+ G+V + A P R AQ LAR + Q+ T Sbjct: 3 QRGFTLLEMMLILLLMGVSAGMV-LLAFPASRDD--SAAQTLARFEAQLRFVQQRGLQTG 59 Query: 71 RPVAWEGDAQGWRFL 85 + W+FL Sbjct: 60 QFFGVSVHPDRWQFL 74
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 33.7 bits (77), Expect = 7e-05 Identities = 25/94 (26%), Positives = 38/94 (40%), Gaps = 11/94 (11%) Query: 8 RRAARRHGFTLLEVLVALTIVAVALTATM-RAMGSMTVASESLQTRMLATWSAENHLAGL 66 R ++ GFTLLE++V + I+ V + + MG+ A + + EN L Sbjct: 2 RATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVA--LENALDMY 59 Query: 67 RL-AHAYPEPGMRGFACPQGDAQLWCEETVAPTP 99 +L H YP QG L T+ P Sbjct: 60 KLDNHHYP-------TTNQGLESLVEAPTLPPLA 86
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 36.8 bits (85), Expect = 2e-05 Identities = 27/75 (36%), Positives = 39/75 (52%), Gaps = 7/75 (9%) Query: 1 MRAISSDRVRGFTLLELLVAITLLAILAVLAWRGLDSMTRTHEALAQRDE-RIEALKTAY 59 MRA +D+ RGFTLLE++V I ++ +LA L L M +A Q+ I AL+ A Sbjct: 1 MRA--TDKQRGFTLLEIMVVIVIIGVLASLVVPNL--MGNKEKADKQKAVSDIVALENAL 56 Query: 60 AQFDADCTQLADPST 74 + D P+T Sbjct: 57 DMYKLDNHHY--PTT 69
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 340 bits (873), Expect = e-112 Identities = 143/430 (33%), Positives = 211/430 (49%), Gaps = 51/430 (11%) Query: 251 IRAANQSALNLLGRTRQSLLGQPV-----ETVFDLTADALLARATDSGGVAWPLHTHQGR 305 + +++A +LL R +++ PV + F A A D + P + Sbjct: 55 VVMPDENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDY--LPKPFDLTELI 112 Query: 306 LLFGLLRAPRPRPTADAAPASPPMPATPGLCLQADGLRTGFHRALRVFEHDVPLLLHGET 365 G++ P + L ++ ++ + R+ + D+ L++ GE+ Sbjct: 113 ---GIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGES 169 Query: 366 GTGKEAFARAVHQASSRAAQPFVAVNCAAIPETLIESELFGYRGGSFTGARREGMRGKLQ 425 GTGKE ARA+H R PFVA+N AAIP LIESELFG+ G+FTGA+ G+ + Sbjct: 170 GTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRST-GRFE 228 Query: 426 QADGGTLFLDEIGDMPLALQSRLLRVLEERAVVPIGG-EAQTVDVRIVSASHRDMEARVR 484 QA+GGTLFLDEIGDMP+ Q+RLLRVL++ +GG DVRIV+A+++D++ + Sbjct: 229 QAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSIN 288 Query: 485 DGRFREDLYYRLNGLRITLPPLRERADKAALLAHVLAEESR---GRPARLDDDARDALLA 541 G FREDLYYRLN + + LPPLR+RA+ L +++ R D +A + + A Sbjct: 289 QGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKA 348 Query: 542 QPWPGNVRQLRNVLRTLVALSDDGRIRLRDLPPELRPPAMASAAAPAP------------ 589 PWPGNVR+L N++R L AL I + ELR S A Sbjct: 349 HPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAV 408 Query: 590 ------------------------LDNAEKAALLAALQAQQWRMTHAAKALGISRNTLYR 625 L E +LAAL A + AA LG++RNTL + Sbjct: 409 EENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRK 468 Query: 626 KLRKHGIARP 635 K+R+ G++ Sbjct: 469 KIRELGVSVY 478
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 28.1 bits (62), Expect = 0.044 Identities = 29/109 (26%), Positives = 44/109 (40%), Gaps = 13/109 (11%) Query: 169 GQWIAISGIG-GLGHVAVQYAVAMGLHVVAVDVAPEKLALARELGARLSVDASQ-----Q 222 G+ I+G G+G + + G H+ AVD PEKL + A + Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVR 67 Query: 223 DPAAV------IQKEVGGV-HGVLVTAVSRSAFAQALGMVRRGGTVSLN 264 D AA+ I++E+G + V V V R +L T S+N Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVN 116
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 27.3 bits (60), Expect = 0.042 Identities = 18/156 (11%), Positives = 48/156 (30%), Gaps = 15/156 (9%) Query: 18 ERIARRVRDLRAARGY---TLDALAARCGVSRSMISLIERGAASPTAVVLDKLAAGLGVS 74 + I L + +G +L +A GV+R I + + + ++ + Sbjct: 14 QHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSD----LFSEIWELSESN 69 Query: 75 LASLFGGEREGVPAQPLMRRAQQAQWRDPASGYVRRNLSPPDWPSPIQLVEVNFPAGARV 134 + L + P PL + R+ + ++ ++++ + Sbjct: 70 IGELELEYQAKFPGDPL------SVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEM 123 Query: 135 AYETGGRENAMQQQVWVIDGRIDVMLGDQRHELHPG 170 A + N + I+ + + + L Sbjct: 124 AVVQQAQRNLCLESYDRIEQTLKHCI--EAKMLPAD 157
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.2 bits (68), Expect = 0.031 Identities = 31/264 (11%), Positives = 67/264 (25%), Gaps = 29/264 (10%) Query: 325 DELEADLVSARNRFLLLGLALGALLAGGLYWMLRRAVSAPLAEVAGVARRVAAGDLTHR- 383 LE R L+ + L +V + VA ++ + Sbjct: 44 AHLELIETPVSRRPRLVAYFIMGFLVIAFIL----SVLGQVEIVATANGKLTHSGRSKEI 99 Query: 384 --FSGTRRDEI----------GQLMHAINGLGDGLSGIVDKVRASASTIASSTGQIAAGN 431 + EI G ++ + LG + + + + + QI + + Sbjct: 100 KPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRS 159 Query: 432 VDLSARTEAQAGNLERTASSIEQLAATVRQNADSAQHAHDMVQSASEAANAGGRTVARLV 491 ++L+ E + + + E+ + + E L Sbjct: 160 IELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELN---------LD 210 Query: 492 GTMSGIHTTAQKIADITGIIDGIAFQTNI---LALNAAVEAARAGEQGRGFAVVAGEVRS 548 + T +I + + + L A+ EQ + E+R Sbjct: 211 KKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRV 270 Query: 549 LAQRSAAAAKEIKELISRSVQEVQ 572 + EI Q Sbjct: 271 YKSQLEQIESEILSAKEEYQLVTQ 294
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 59.0 bits (143), Expect = 3e-12 Identities = 30/141 (21%), Positives = 52/141 (36%), Gaps = 24/141 (17%) Query: 1 MNVLITGARGYLGALLSVAL-SGSHDVV----------------RTSRGDISNSLFQYLD 43 M L+TGA G++G +S L H VV R F +D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 44 VTDADCVKRVVAATVPDVIIHAAAMANLSVCEANPEAAFLVNAEGTLNVVQAANEVG-AR 102 + D + + + A+ + + + + NP A N G LN+++ Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 103 VLFISTLAASNPSIVYGRSKS 123 +L+ S+ S VYG ++ Sbjct: 121 LLYASS------SSVYGLNRK 135
>SURFACELAYER#Lactobacillus surface layer protein signature. Length = 439 Score = 29.6 bits (66), Expect = 0.025 Identities = 59/285 (20%), Positives = 102/285 (35%), Gaps = 29/285 (10%) Query: 1 MKRLLYLAAPAIVGAALLCLPAPSSAAANAVGANAVIGEFATPSA-ASSPQGVDVAGDGS 59 MK+ L + + A AA L AP +A A V A I + +A ++ VDV S Sbjct: 1 MKKNLRIVSAA---AAALLAVAPIAATAMPVNAATTINADSAINANTNAKYDVDVTPSIS 57 Query: 60 VWYSETTAGKIAVLRPDGSSAEFPVPNGGQPFILKVADD--GVWFTDSGTRAIGHLDPAT 117 + + + + P + G+ + + D TDS + + Sbjct: 58 AIAAVAKSDTMPAI-PGSLTGSISASYNGKSYTANLPKDSGNATITDSNNNTVKPAELEA 116 Query: 118 GTVETYAIPSGASPFFIQVGPDGSKWFTETAGIGRLSPNGEFTEWTVTLEHADDNME--Q 175 T +P + F GS+ + IG +PN FTE + D + Sbjct: 117 DKAYTVTVPDVSFNF-------GSENAGKEITIGSANPNVTFTE-----KTGDQPASTVK 164 Query: 176 LSLDPWGNVWFVERNFDGIGAAGTNKVRRLNPYSNVISTYRVPTLGGTPSGVVANANGSV 235 ++LD G + A T +N Y ++T T G + A+ G + Sbjct: 165 VTLDQDGVAKLSSVQIKNVYAIDTTYNSNVNFYD--VTTGATVTTGAV--SIDADNQGQL 220 Query: 236 WVSEYYANAIALLNPFAAPHSDEVVQPNALKADSRTASVSPIRAA 280 ++ A + FAA + + Q + D+ TA ++A Sbjct: 221 NITSVVAAINS--KYFAAQYDKK--QLTNVTFDTETAVKDALKAQ 261
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 29.0 bits (65), Expect = 0.020 Identities = 19/100 (19%), Positives = 34/100 (34%), Gaps = 8/100 (8%) Query: 136 YWTGKRFAPEAVAS-IDQAVSHFAAKVPGQRIHLIGYSGG-----GALAVLVAARRTDVA 189 YW K P+ V + + A+ Q++ LIGYS G L + A R +V Sbjct: 90 YWKQK--DPKDVTQDTLAIIDKYQAEFGTQKVILIGYSFGAEVIPFVLNEMPARYRKNVL 147 Query: 190 SIRTVAGNLDHAFVNRLHDVSSMPQSENAIDFAQRVASIP 229 ++ + F + ++ + V Sbjct: 148 GAVLLSPSQSSDFEIHVSEMVTSDNQSARYLTLPEVNKQT 187
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 31.1 bits (70), Expect = 0.003 Identities = 11/59 (18%), Positives = 19/59 (32%) Query: 135 SVAIILYLARRYDQAREELNKALEIDPNHFLLHFRLGLVYQQQKLFHDAIEEMQKAVTL 193 S+A Y + +Y+ A + +D LG Q + AI + Sbjct: 41 SLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIM 99
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 30.8 bits (69), Expect = 0.002 Identities = 15/43 (34%), Positives = 22/43 (51%), Gaps = 2/43 (4%) Query: 37 IGVAAKISDLYPHVINVYMNATLPPLRKKSWAGYYFKTLIPYF 79 +G ++ + +N +N L L KKSW GY KT+ YF Sbjct: 701 VGGRSQGEENDWKDMNSKLNDILKELSKKSWNGY--KTVTAYF 741
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.1 bits (83), Expect = 2e-05 Identities = 17/86 (19%), Positives = 31/86 (36%), Gaps = 8/86 (9%) Query: 54 TAPACKYFVAMESGLLVGVCALK----DRKHIYHLFVAPEAQGRGVARALWEYARADAEL 109 A F+ +G ++ I + VA + + +GV AL A A+ Sbjct: 63 EGKAA--FLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKE 120 Query: 110 DGATGSF--TVNSSLHAVPVYERLGF 133 + G T + ++ A Y + F Sbjct: 121 NHFCGLMLETQDINISACHFYAKHHF 146
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 29.9 bits (67), Expect = 0.023 Identities = 12/70 (17%), Positives = 20/70 (28%), Gaps = 2/70 (2%) Query: 9 AAALLSVATAHAQV-LPPAPPGPVLEDPAQRAQRERQDTERRREATQPAPQIAVAPSVPD 67 A L + ++ P P + PA + +P P+ P P Sbjct: 30 AGLLYTSVHQVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVV-EPEPEPEPIPEPPK 88 Query: 68 DAAVDAVAEP 77 +A V Sbjct: 89 EAPVVIEKPK 98
>PF05860#haemagglutination activity domain. Length = 117 Score = 75.6 bits (186), Expect = 1e-18 Identities = 28/117 (23%), Positives = 47/117 (40%), Gaps = 4/117 (3%) Query: 28 AGIVPDG--GTATTVTTGANGRPVVNIAPSTAGVSHNIYTSFNVGPVGADLNNAIVRART 85 A I PD + +TT N R + + + + H+ + F+V G N + Sbjct: 1 AQITPDTTLPINSNITTEGNTRIIERGTQAGSNLFHS-FQEFSVPTSGTAFFNNPTNIQN 59 Query: 86 IVNQVTSTDPSLIQGNIAVLGPRANVIIANPNGITVDGGSFTNTGNVALTTGQVSFN 142 I+++VT S I G I AN+ + NPNGI + + G + + Sbjct: 60 IISRVTGGSVSNIDGLIRANA-TANLFLINPNGIIFGQNARLDIGGSFVGSTANRLK 115
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 452 bits (1164), Expect = e-144 Identities = 226/1054 (21%), Positives = 423/1054 (40%), Gaps = 69/1054 (6%) Query: 8 LSALAVRERAVTLFLICLISLAGLISFFKLGRAEDPAFTVKVMTIITAWPGATAQEMQDQ 67 ++ +R L ++ +AG ++ +L A+ P +++ +PGA AQ +QD Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 68 VAEKIEKRIQELRWYDRTETYT-RPGLAFTTLTLLDSTPPSEVQEEFYQARKKVSDEVAN 126 V + IE+ + + + + G TLT T P Q Q + K+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQV---QVQNKLQLATPL 117 Query: 127 LPPGVIGPMVNDEYADVTFAL---FALKAQGEPQRVLVRDAE-TLRQRLLHVPGVKKVNI 182 LP V ++ E + ++ + F G Q + ++ L + GV V + Sbjct: 118 LPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQL 177 Query: 183 IGEQSE-RIYVEFSHDRLATLGVSPQEVFAALNNQNALTAAGSVET------KGPQVFIR 235 G Q RI+++ D L ++P +V L QN AAG + + I Sbjct: 178 FGAQYAMRIWLDA--DLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASII 235 Query: 236 LDGAFDELQKIRDTPVVSQ--GRTLKLSDIATVKRGYEDPATFMVRNGGQPALLLGIVMR 293 F ++ + G ++L D+A V+ G E+ R G+PA LGI + Sbjct: 236 AQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVI-ARINGKPAAGLGIKLA 294 Query: 294 EGWNGLDLGKALDKEVGAINADMPLGMSLTKVTDQAVNISAAVDEFMLK-FFAALLVVML 352 G N LD KA+ ++ + P GM + D + ++ E + F A +LV ++ Sbjct: 295 TGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLV 354 Query: 353 VSFVSMGWRAGLVVAAAVPLTLAVVFVVMAATGKNFDRITLGSLILALGLLVDDAIIAIE 412 + RA L+ AVP+ L F ++AA G + + +T+ ++LA+GLLVDDAI+ +E Sbjct: 355 MYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVE 414 Query: 413 MMV-VKMEEGYSRVAASAYAWSHTAAPMLSGTLVTAVGFMPNGFARSTAGEYTSNMFWIV 471 + V ME+ A+ + S ++ +V + F+P F + G + Sbjct: 415 NVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITI 474 Query: 472 GIALIASWVVAVVFTPYLGVKMLPDFKKVE--------GGHDAIYDTPRYNRFRALLGRV 523 A+ S +VA++ TP L +L G + +D N + +G++ Sbjct: 475 VSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFD-HSVNHYTNSVGKI 533 Query: 524 IARKWLVAGSVVGLFALAILGMAVVKKQFFPISDRPEVLVEVQMPYGTSINQTSAATAKL 583 + + A ++ + F P D+ L +Q+P G + +T ++ Sbjct: 534 LGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQV 593 Query: 584 EAWLAKQKEAQIVTSYVGQGAPRFYLAMGPELPDSSFAKIVI-----RTDSQEERDALKQ 638 + K ++A + + + G + + ++ A + + R + +A+ Sbjct: 594 TDYYLKNEKANVESVFTVNG-----FSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIH 648 Query: 639 RLRQAIADGLAPEARVRVTQLVFGPYSPFPVAYRVTGPDAETLRRIAADVRQVMDAS--- 695 R + + + V + TG D E + + + A Sbjct: 649 RAKMELGK--IRDGFVIPFNM-----PAIVELGTATGFDFELIDQAGLGHDALTQARNQL 701 Query: 696 --------PMMRTVNTDWGMRVPTLHFTLQQDRLQAVGLTSSAVAQQLQFLLNGIPVTAV 747 + +V + + Q++ QA+G++ S + Q + L G V Sbjct: 702 LGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDF 761 Query: 748 REDIRTVQVTARSAGDIRLDPAKIGDFTLAGANGQRVPLSQVGKIDVRMEEPIIRRRDRM 807 + R ++ ++ R+ P + + ANG+ VP S P + R + + Sbjct: 762 IDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGL 821 Query: 808 PTITVRGDIADGLQPPDVSTALSKQLQPIIEKLPSGYRIEQAGSIEESGKATKAMLPLFP 867 P++ ++G+ A G D + + KLP+G + G + + L Sbjct: 822 PSMEIQGEAAPGTSSGDAMALMEN----LASKLPAGIGYDWTGMSYQERLSGNQAPALVA 877 Query: 868 IMLAVTLLILIFQVRSIPAMVMVFLTSPLGLIGVVPTLILFGQPFGINALVGLIALSGIL 927 I V L L S V V L PLG++GV+ LF Q + +VGL+ G+ Sbjct: 878 ISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLS 937 Query: 928 MRNTLILIGQIQHNKE-EGLDPFTAVVEATVQRARPVILTALAAILAFIPLTHSVFWGA- 985 +N ++++ + E EG A + A R RP+++T+LA IL +PL S G+ Sbjct: 938 AKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSG 997 Query: 986 ----LAYTLIGGTFAGTILTLVFLPAMYSIWFRI 1015 + ++GG + T+L + F+P + + R Sbjct: 998 AQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRRC 1031 Score = 83.7 bits (207), Expect = 2e-18 Identities = 55/323 (17%), Positives = 126/323 (39%), Gaps = 20/323 (6%) Query: 712 LHFTLQQDRLQAVGLT----SSAVAQQLQFLLNGIPVTAVREDIRTVQVTARSAGDIRLD 767 + L D L LT + + Q + G + + + + + + Sbjct: 184 MRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK-N 242 Query: 768 PAKIGDFTL-AGANGQRVPLSQVGKIDVRMEEPIIRRR-DRMPTITVRGDIADGLQPPDV 825 P + G TL ++G V L V ++++ E + R + P + +A G D Sbjct: 243 PEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDT 302 Query: 826 STALSKQLQPIIEKLPSGYRIE----QAGSIEESGKATKAMLPLFPIMLAVTLLILIFQV 881 + A+ +L + P G ++ ++ S L IML L++ +F + Sbjct: 303 AKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTL-FEAIMLVF-LVMYLF-L 359 Query: 882 RSIPAMVMVFLTSPLGLIGVVPTLILFGQPFGINALVGLIALSGILMRNTLILIGQIQ-H 940 +++ A ++ + P+ L+G L FG + G++ G+L+ + ++++ ++ Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 941 NKEEGLDPFTAVVEATVQRARPVILTALAAILAFIPL-----THSVFWGALAYTLIGGTF 995 E+ L P A ++ Q ++ A+ FIP+ + + + T++ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 996 AGTILTLVFLPAMYSIWFRIRPN 1018 ++ L+ PA+ + + Sbjct: 480 LSVLVALILTPALCATLLKPVSA 502
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 39.8 bits (93), Expect = 1e-05 Identities = 18/118 (15%), Positives = 40/118 (33%), Gaps = 9/118 (7%) Query: 70 GKVLERLVDAGQTVKRGQPLMRIDPVD-----LKLAAHAQQEAVSAARARAQQTA--EDE 122 V E +V G++V++G L+++ + LK + Q + R + + ++ Sbjct: 105 SIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNK 164 Query: 123 ARYRDLRGTGAISASAYDQAKAAADAAKAQLSAAEAQADVARNASRYAELLADGDGVV 180 L + ++ K Q S + Q + A+ V+ Sbjct: 165 LPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKE--LNLDKKRAERLTVL 220
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 61.2 bits (148), Expect = 8e-14 Identities = 41/199 (20%), Positives = 66/199 (33%), Gaps = 16/199 (8%) Query: 17 DVRDQIVAAATEHFSRYGYEKTAVSDLAKAIGFSKAYIYKFFESKQAIGEMICANCLREI 76 + R I+ A FS+ G T++ ++AKA G ++ IY F+ K + I I Sbjct: 11 ETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNI 70 Query: 77 EADVSAALAE-ADSPPEKLRRMFKAL-----TEASLRLFSHDRKLYEIAASAATERWQAV 130 A+ P LR + + TE RL QA Sbjct: 71 GELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQ 130 Query: 131 IAYEERIQKVLRDVLQEGRETGDFERKTPLDEATTAIYLVMRPYMNPLLLQY-----SFD 185 + L+ E L AI +MR Y++ L+ + SFD Sbjct: 131 RNLCLESYDRIEQTLKHCIEAKML--PADLMTRRAAI--IMRGYISGLMENWLFAPQSFD 186 Query: 186 YTESAPGLLSSLVLRSLSP 204 + A +++L Sbjct: 187 LKKEA-RDYVAILLEMYLL 204
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 104 bits (260), Expect = 6e-29 Identities = 53/186 (28%), Positives = 86/186 (46%), Gaps = 8/186 (4%) Query: 5 KVVLITGVSSGIGRATAAKFALRGCRVFGTVRNLAKAQPIPGVELVE--------MDIRD 56 K+ ITG + GIG A A A +G + N K + + E D+RD Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 57 QASVQQGIQTLIAQAKRIDVLVNSAGVTLLGATEETSIAEAQALFDTNVFGILRTTQAAL 116 A++ + + + ID+LVN AGV G S E +A F N G+ +++ Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 117 PHMRAQRSGRIINISSVLGFLPAPYMGLYSASKHAVEGMSETLDHEVRKFGIRVVLVEPS 176 +M +RSG I+ + S +P M Y++SK A ++ L E+ ++ IR +V P Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 177 FTKTSL 182 T+T + Sbjct: 189 STETDM 194
>PF05272#Virulence-associated E family protein Length = 892 Score = 49.3 bits (117), Expect = 6e-08 Identities = 72/273 (26%), Positives = 105/273 (38%), Gaps = 57/273 (20%) Query: 24 ALLARLEFVLSVLFPAGKKRRGTFVVGDILGSPGDSLEVVLDGEKAGLWTDRATGDGG-D 82 ALL R + +L P G + G + G GDS +V + G W D +TG+ G D Sbjct: 17 ALLTRAKDLLPEWLPGGVLVGHEYECGSLAGGKGDSCKVNV---TTGKWCDFSTGESGRD 73 Query: 83 IFDLIAAQAGLRVSTDFSGVL-ERALQ-----LLGQASKQPVRRKRREPPTDDLGPETAK 136 + DL A GL+VS + V E L+ ++G + P + R P E Sbjct: 74 LLDLYAEIHGLKVSKAAAQVAREEGLESVAGIVMGAPAGAPAPKPPRPEPPPRPVVEKEC 133 Query: 137 WDYLDAAGKLIGVVYRYDPPGRGKEFRPWDAKRRKMAPP--------------------- 175 W+ + + + P +G+E + R P Sbjct: 134 WETIQPVPEHAVPPSFWHPAPKGREPDKIEHTARYQVGPVLWGYVVRFIKSDGDKLTLPY 193 Query: 176 -------------------EPRPLYNQPGLATATQ-VVLVEGEK---CAQALIDIG---I 209 +PRPLY A ++ VVLVEGE+ C Q L+D G + Sbjct: 194 VYSRSQRDGSEAWKWRGWDDPRPLYFPSHRAPESRTVVLVEGERKADCLQQLLDAGAPGV 253 Query: 210 VATTAMHGANAPVEKTDWSPLAGKAVLIWPDRD 242 + G + K DWS LAG V++WPD D Sbjct: 254 YCVASWPGGSNGWPKADWSWLAGCTVVLWPDCD 286
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 28.0 bits (62), Expect = 0.018 Identities = 11/18 (61%), Positives = 14/18 (77%) Query: 13 AALVPMALAAGAAHAVEV 30 A ++P LAAGAAHA E+ Sbjct: 7 ALVIPALLAAGAAHAAEI 24
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.8 bits (67), Expect = 0.043 Identities = 16/105 (15%), Positives = 33/105 (31%), Gaps = 2/105 (1%) Query: 636 DAPALLALVRHDYAGFARQLLRERKQACLPPFAYQALLTAEHRELARALEFLGAARAAGQ 695 D AL + H + G R+L ++ Q ++T E E E + Sbjct: 339 DQEALELMKAHPWPGNVRELENLVRRLTA--LYPQDVITREIIENELRSEIPDSPIEKAA 396 Query: 696 AVAEAQSLPVQLHDPVPMTMVRLANRERAQLLLESASRAALQRLL 740 A + + S+ + + + + L + L+ Sbjct: 397 ARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLI 441
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 42.7 bits (100), Expect = 2e-06 Identities = 26/93 (27%), Positives = 35/93 (37%), Gaps = 1/93 (1%) Query: 666 PMPSAQQERPRSEPPAQARPEPQPHPAPVPVPHQPEARIEAPRPMPQPHPVEIRPPQPQP 725 P + + P PEP+P P P P P + IE P+P P+P P ++ Q QP Sbjct: 52 PADLEPPQAVQPPPEPVVEPEPEPEPIPEP-PKEAPVVIEKPKPKPKPKPKPVKKVQEQP 110 Query: 726 QPQPHVVEMRPPQPQPQPRPEVRPPQPPQPPQP 758 + VE RP P P Sbjct: 111 KRDVKPVESRPASPFENTAPARLTSSTATAATS 143 Score = 40.7 bits (95), Expect = 9e-06 Identities = 23/107 (21%), Positives = 35/107 (32%) Query: 681 AQARPEPQPHPAPVPVPHQPEARIEAPRPMPQPHPVEIRPPQPQPQPQPHVVEMRPPQPQ 740 PQ P +PE E P+ PV I P+P+P+P+P V+ QP+ Sbjct: 52 PADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPK 111 Query: 741 PQPRPEVRPPQPPQPPQPRVEHHEAAPAQPHPQAGHNEAQQRDTDHR 787 +P P P + + + A R Sbjct: 112 RDVKPVESRPASPFENTAPARLTSSTATAATSKPVTSVASGPRALSR 158 Score = 35.0 bits (80), Expect = 7e-04 Identities = 20/105 (19%), Positives = 35/105 (33%), Gaps = 5/105 (4%) Query: 651 PQPESMPGTPREERRPMPSAQQERPRSEPPAQARPEPQPHPAPVPVPHQPEARIEAPRPM 710 P+++ P P P + + +P+P P P P +P +++ +P Sbjct: 56 EPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKP---KPVKKVQE-QPK 111 Query: 711 PQPHPVEIRPPQPQPQPQPHVVEMRPPQPQPQPRPEVRPPQPPQP 755 PVE RP P P + +P P+ Sbjct: 112 RDVKPVESRPASPFENTAPARL-TSSTATAATSKPVTSVASGPRA 155 Score = 32.7 bits (74), Expect = 0.004 Identities = 24/80 (30%), Positives = 31/80 (38%), Gaps = 2/80 (2%) Query: 704 IEAPRPMPQPHPVEIRPPQPQPQPQPHVVEMRPPQPQPQPRPEVRPPQPPQPPQPRVEHH 763 IE P P QP V + P PQ V P +P+P PE P P + P + Sbjct: 36 IELPAP-AQPISVTMVTPADLEPPQA-VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPK 93 Query: 764 EAAPAQPHPQAGHNEAQQRD 783 +P P E +RD Sbjct: 94 PKPKPKPKPVKKVQEQPKRD 113 Score = 32.7 bits (74), Expect = 0.005 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 12/87 (13%) Query: 695 PVPHQP-EARIEAPRPMPQPHPVEIRPP---QPQPQPQPHVVEMRPPQPQPQPRPEVRPP 750 P P QP + P + P V+ P +P+P+P+P + E P +P+ +P Sbjct: 39 PAPAQPISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEP-IPEPPKEAPVVIEKPKPKPK 97 Query: 751 QPPQP-------PQPRVEHHEAAPAQP 770 P+P P+ V+ E+ PA P Sbjct: 98 PKPKPVKKVQEQPKRDVKPVESRPASP 124
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 28.6 bits (64), Expect = 0.031 Identities = 16/54 (29%), Positives = 23/54 (42%), Gaps = 7/54 (12%) Query: 166 ELGVHAHRRYLERRG-----TPATLDDLAGHALIGYDKETAFIRGMKGQVPWMR 214 LG+ A + L + T A L + +IG+ ET G+K V W R Sbjct: 278 ALGIEAKKNMLPLQPGDVLETSADTKAL--YEVIGFTPETTVKDGVKNFVNWYR 329
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 30.5 bits (69), Expect = 0.009 Identities = 31/154 (20%), Positives = 52/154 (33%), Gaps = 37/154 (24%) Query: 9 LVLGATGGIGGEMARRLTAHGWRVRAL------------HRNPDALARRDPAFEWVRGDA 56 LV GA G IG +++RL G +V + + LA+ P F++ + D Sbjct: 4 LVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQ--PGFQFHKIDL 61 Query: 57 MVR------------DDVVAAARGAAVIVHAVNPPGY--RNWAGLVLPMIDHTIAAARAC 102 R + V + AV NP Y N G + + + R Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFL-----NILEGCRHN 116 Query: 103 G-ARVVLPGT--VYNFGPDAFPVLCETSAQQPLT 133 ++ + VY P + S P++ Sbjct: 117 KIQHLLYASSSSVYGLNRK-MPFSTDDSVDHPVS 149
>PF06580#Sensor histidine kinase Length = 349 Score = 31.0 bits (70), Expect = 0.004 Identities = 15/73 (20%), Positives = 32/73 (43%), Gaps = 1/73 (1%) Query: 23 SFYAMLSLGLAVIFGLLNVINFAHG-ALFMLGAVLTWMGLSYLDLPYWVMLVAAPLAVGV 81 Y + G A ++G + + A+ ++G VLT S++ W+ L + + V Sbjct: 21 GVYTLTGFGFASLYGSPKLHSMIFNIAISLMGLVLTHAYRSFIKRQGWLKLNMGQIILRV 80 Query: 82 VGVVIERTMLRFI 94 + + M+ F+ Sbjct: 81 LPACVVIGMVWFV 93
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 493 bits (1270), Expect = e-172 Identities = 203/561 (36%), Positives = 304/561 (54%), Gaps = 44/561 (7%) Query: 1 MDIKRTILWVIFSLSVVLLFDNWQRANGHQSMFFPTPQTVTTTAAAPGGTPAGDVPKAAA 60 MD +R +L + +++ W++ P PQ TT A Sbjct: 1 MDSQRNLLVIALLFVSFMIWQAWEQDKN------PQPQAQQTTQTTT-----------TA 43 Query: 61 PAAAGSQAAPATGAVSQTPASEKIVVTTDVIRATVDTAGAIVTKLELL---TQKDHDGNP 117 +A Q PA+G I V TDV+ T++T G V + L + + P Sbjct: 44 AGSAADQGVPASGQGKL------ISVKTDVLDLTINTRGGDVEQALLPAYPKELNST-QP 96 Query: 118 MVLFDRSLERTYLARSGLIGGDFPNHTT-----VFTASAGPRDLGTGGE---VSLTLTAD 169 L + S + Y A+SGL G D P++ ++ L G V +T T D Sbjct: 97 FQLLETSPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYT-D 155 Query: 170 KGGAKLAKTYVFKRGSYVIDTRFDVTNDGAAPINPTLYMELARDGGAVEQSRFYS----- 224 G KT+V KRG Y ++ ++V N G P+ + + +L + S Sbjct: 156 AAGNTFTKTFVLKRGDYAVNVNYNVQNAGEKPLEISSFGQLKQSITLPPHLDTGSSNFAL 215 Query: 225 -TFTGPAVYTDTDHYHKITFADIDKSKAHVPAPTDSGWVAMVQHYFASAWIPAASAKREF 283 TF G A T + Y K F I ++ + GWVAM+Q YFA+AWIP F Sbjct: 216 HTFRGAAYSTPDEKYEKYKFDTI-ADNENLNISSKGGWVAMLQQYFATAWIPHNDGTNNF 274 Query: 284 YVDRIDTNFYRVGMQQALGTVAPGASVSATARLFAGPQEERMLEGITPGLELVKDYGWLT 343 Y + +G + V PG + + + L+ GP+ + + + P L+L DYGWL Sbjct: 275 YTANLGNGIAAIGYKSQPVLVQPGQTGAMNSTLWVGPEIQDKMAAVAPHLDLTVDYGWLW 334 Query: 344 IIAKPLFWLLEKIHKLLGNWGWSIVALTVLVKLVFFPLSATSYRSMAKMKDLQPRMTAIR 403 I++PLF LL+ IH +GNWG+SI+ +T +V+ + +PL+ Y SMAKM+ LQP++ A+R Sbjct: 335 FISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMR 394 Query: 404 ERHKGDPQKMNQEMMTLYRTEKVNPLGGCLPIVIQIPVFIALYWVLLSSVEMRGAPWLGW 463 ER D Q+++QEMM LY+ EKVNPLGGC P++IQ+P+F+ALY++L+ SVE+R AP+ W Sbjct: 395 ERLGDDKQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYYMLMGSVELRQAPFALW 454 Query: 464 VHDLASPDPFYILPILMAVSMFVQTRLNPTP-PDPVQAKMMMFMPIAFSVMFFFFPAGLV 522 +HDL++ DP+YILPILM V+MF +++PT DP+Q K+M FMP+ F+V F +FP+GLV Sbjct: 455 IHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLV 514 Query: 523 LYWVVNNCLSIAQQWSINRML 543 LY++V+N ++I QQ I R L Sbjct: 515 LYYIVSNLVTIIQQQLIYRGL 535
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 35.6 bits (82), Expect = 4e-04 Identities = 29/95 (30%), Positives = 42/95 (44%), Gaps = 19/95 (20%) Query: 280 TIQIEGIPLNIVDTAGLRDTEDEVERIGIERTWAAIARADVVLHLLDAADYRAHGLSAED 339 + Q E +NI+DT G D EV R +++ D + L+ A D G+ A+ Sbjct: 62 SFQWENTKVNIIDTPGHMDFLAEVYR--------SLSVLDGAILLISAKD----GVQAQ- 108 Query: 340 AAIDARIAEHVPP--GVPTLRVINKIDLAGAAVPG 372 RI H G+PT+ INKID G + Sbjct: 109 ----TRILFHALRKMGIPTIFFINKIDQNGIDLST 139
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1184 bits (3064), Expect = 0.0 Identities = 586/1036 (56%), Positives = 753/1036 (72%), Gaps = 7/1036 (0%) Query: 1 MAKFFIDRPVFAWVLALFIIVAGAISITQLPIAQYPTIAPPSIIITATYPGASAKTLDDA 60 MA FFI RP+FAWVLA+ +++AGA++I QLP+AQYPTIAPP++ ++A YPGA A+T+ D Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTSIIEQEMNGADGLLYIESVSQAGNGQATITVTFKPGTDPALAQVDVQNRLKRVEARLP 120 VT +IEQ MNG D L+Y+ S S G TIT+TF+ GTDP +AQV VQN+L+ LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTS-DSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLP 119 Query: 121 SSVTQQGVQVDKTRSNFLLFATLISKDGKMDPVALGDYISRNVLNEVKRVPGVGQAVLFG 180 V QQG+ V+K+ S++L+ A +S + + DY++ NV + + R+ GVG LFG Sbjct: 120 QEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG 179 Query: 181 TERAMRIWIDPAKLVGYKLTPTDVYNAIRNQNALVSAGTLGDLPSTSDQPIAATVVVEGQ 240 + AMRIW+D L YKLTP DV N ++ QN ++AG LG P+ Q + A+++ + + Sbjct: 180 AQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 241 MTTTEQFGNIVLVSKPDGSQVRIKDVARLELGGQTYATSARINGQPISAIGVQLSPTGNA 300 E+FG + L DGS VR+KDVAR+ELGG+ Y ARING+P + +G++L+ NA Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 301 LGTAKAVKAKLDELSKYFPAGVEYKIPYDTSKFVQISIEEVVKTLFEAMALVFLVMLVFL 360 L TAKA+KAKL EL +FP G++ PYDT+ FVQ+SI EVVKTLFEA+ LVFLVM +FL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 361 QNIRYTLIPSIVVPISLLGAFATMNALGFSINVLTMFGLVLAIGILVDDAIVVVENVERI 420 QN+R TLIP+I VP+ LLG FA + A G+SIN LTMFG+VLAIG+LVDDAIVVVENVER+ Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 421 MSQEGLPPREATRKAMGQITGAIIGITLVLMAVFIPMAFFSGSVGAIYRQFSLSMVASIF 480 M ++ LPP+EAT K+M QI GA++GI +VL AVFIPMAFF GS GAIYRQFS+++V+++ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 481 FSALMALTLTPALCSTLLKPIEKGSHHEKKGFFGWFNRMFTSTTDRYQSLVERVLKKTFR 540 S L+AL LTPALC+TLLKP+ H K GFFGWFN F + + Y + V ++L T R Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 541 YMVIYGALIAAVVFLFMRLPSSFLPNEDQGYIITNIQLPPAASANRTLEVIKHVENYYQH 600 Y++IY ++A +V LF+RLPSSFLP EDQG +T IQLP A+ RT +V+ V +YY Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 601 --EKAVENIVAVQGFSFSGNGPNAALVFTTLKDWSSR-GADQSADAVAGRAFGALFGGIR 657 + VE++ V GFSFSG NA + F +LK W R G + SA+AV RA G IR Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKME-LGKIR 658 Query: 658 DAIVFPLNPPPIPELGNATGFTFRLQDRGGLGHDALMAARNQLLGMAGQSKV-LKNVRPD 716 D V P N P I ELG ATGF F L D+ GLGHDAL ARNQLLGMA Q L +VRP+ Sbjct: 659 DGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPN 718 Query: 717 GLEDSPQYQVDIDREKANALGVAFADINNVLSTALGSAYANDFPNYGRQQRVIVQADRIN 776 GLED+ Q+++++D+EKA ALGV+ +DIN +STALG Y NDF + GR +++ VQAD Sbjct: 719 GLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKF 778 Query: 777 RMQPEDIMNLYVRNTQGSMVPMSAFAKGHWVVGPVQLVRYNGYPSVRISGDAATGASTGD 836 RM PED+ LYVR+ G MVP SAF HWV G +L RYNG PS+ I G+AA G S+GD Sbjct: 779 RMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGD 838 Query: 837 AMDEMEHLASRLPAGIGFEWTGQSLQEKSSGSQAPALYALSLLAVFLVLAALYESWSIPA 896 AM ME+LAS+LPAGIG++WTG S QE+ SG+QAPAL A+S + VFL LAALYESWSIP Sbjct: 839 AMALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPV 898 Query: 897 AVILVVPLGVLGALLGVTLRFMPDDVYFKVGLIAVVGLSAKNAILIIEFAKDLQ-AQGKG 955 +V+LVVPLG++G LL TL +DVYF VGL+ +GLSAKNAILI+EFAKDL +GKG Sbjct: 899 SVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKG 958 Query: 956 LIEATLEAVHLRFRPIIMTSFAFILGVLPLAIATGASSASQRAIGTGVMGGMITATVLAV 1015 ++EATL AV +R RPI+MTS AFILGVLPLAI+ GA S +Q A+G GVMGGM++AT+LA+ Sbjct: 959 VVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAI 1018 Query: 1016 VLVPVFFVVVRRIFKG 1031 VPVFFVV+RR FKG Sbjct: 1019 FFVPVFFVVIRRCFKG 1034 Score = 73.7 bits (181), Expect = 3e-15 Identities = 56/331 (16%), Positives = 125/331 (37%), Gaps = 21/331 (6%) Query: 723 QYQVDIDREKANALGVAFADINNVLSTA---LGSAYANDFPNYGRQQRVIVQADRINRMQ 779 ++ +D + N + D+ N L + + P QQ + Sbjct: 183 AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKN 242 Query: 780 PEDIMNLYVR-NTQGSMVPMSAFAKGHWVVGPVQ-LVRYNGYPSVRISGDAATGASTGDA 837 PE+ + +R N+ GS+V + A+ + R NG P+ + ATGA+ D Sbjct: 243 PEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDT 302 Query: 838 MD----EMEHLASRLPAGIGFEWT-GQSLQEKSSGSQAPALYALSLLAVFLVLAALYESW 892 ++ L P G+ + + + S + +++ VFLV+ ++ Sbjct: 303 AKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNM 362 Query: 893 SIPAAVILVVPLGVLGAL-----LGVTLRFMPDDVYFKVGLIAVVGLSAKNAILIIE-FA 946 + VP+ +LG G ++ + G++ +GL +AI+++E Sbjct: 363 RATLIPTIAVPVVLLGTFAILAAFGYSINTLT-----MFGMVLAIGLLVDDAIVVVENVE 417 Query: 947 KDLQAQGKGLIEATLEAVHLRFRPIIMTSFAFILGVLPLAIATGASSASQRAIGTGVMGG 1006 + + EAT +++ ++ + +P+A G++ A R ++ Sbjct: 418 RVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSA 477 Query: 1007 MITATVLAVVLVPVFFVVVRRIFKGSERQRR 1037 M + ++A++L P + + + + Sbjct: 478 MALSVLVALILTPALCATLLKPVSAEHHENK 508
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 45.2 bits (107), Expect = 3e-07 Identities = 36/209 (17%), Positives = 71/209 (33%), Gaps = 30/209 (14%) Query: 99 AQYQASLDSAKAQLARAEATQTQAQLKAERYKPLVATNAISKQDYDDAVAAA-KQATADV 157 + L K+QL + E+ A+ + + Q + + + +Q T ++ Sbjct: 262 VEAVNELRVYKSQLEQIESEILSAKEEYQLVT----------QLFKNEILDKLRQTTDNI 311 Query: 158 GAARAAVETAKLNLGYATVTSPISGR-AGLAQVTEGALVGQG--------SDATLLATVQ 208 G + + + + +P+S + L TEG +V D TL T Sbjct: 312 GLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTA- 370 Query: 209 QIDPIYLTFTQSSTEVMRLQEALKAGKLAAAGDTAAKVTLVTEDGRVYAQTGKLYFSDLT 268 + + F + EA + G KV + D + G ++ ++ Sbjct: 371 LVQNKDIGFINVGQNAIIKVEAFPYTR---YGYLVGKVKNINLDAIEDQRLGLVFNVIIS 427 Query: 269 VDQTTGSITLRAIFPNAERTLLPGMYVRA 297 +++ S + I L GM V A Sbjct: 428 IEENCLSTGNKNIP------LSSGMAVTA 450 Score = 37.1 bits (86), Expect = 1e-04 Identities = 16/105 (15%), Positives = 38/105 (36%) Query: 64 RVAQVRARVAGIVLKRTYQEGSDVKANDVLFRIDPAQYQASLDSAKAQLARAEATQTQAQ 123 R +++ IV + +EG V+ DVL ++ +A ++ L +A QT+ Q Sbjct: 95 RSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQ 154 Query: 124 LKAERYKPLVATNAISKQDYDDAVAAAKQATADVGAARAAVETAK 168 + + + + + ++ + T + Sbjct: 155 ILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQ 199
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 126 bits (317), Expect = 3e-38 Identities = 75/209 (35%), Positives = 111/209 (53%), Gaps = 1/209 (0%) Query: 1 MVRRTKEEALETRNRILDAAEEVFYVRGVARTSLSDIAQAAGVTRGAIYWHFRNKADVFA 60 M R+TK+EA ETR ILD A +F +GV+ TSL +IA+AAGVTRGAIYWHF++K+D+F+ Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 AMCERVKLPM-ETLCSPLGVEPNDPLGELRNVANFVLQQLVEDMHWRRVFEIMFNKCEFV 119 + E + + E P DPL LR + VL+ V + R + EI+F+KCEFV Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 120 EDTSPILKRQQESFEEGLARLTHIIGQAARRGQLPPDLDVPLAVAHFHASFGGIMGDYLF 179 + + + + Q+ E R+ + LP DL A G+M ++LF Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180 Query: 180 YPDASSLAVKRERFVDACIDTLKYSPALR 208 P + L + +V ++ P LR Sbjct: 181 APQSFDLKKEARDYVAILLEMYLLCPTLR 209
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 30.2 bits (68), Expect = 0.012 Identities = 20/77 (25%), Positives = 37/77 (48%), Gaps = 2/77 (2%) Query: 26 ALKFERKLSQHTLASYARELAVLQQLGARFAAGIDLMRLQPH--HIRRMMAQLHGGGLSG 83 +L+ + +LS LA R+LA L +D + Q H+ ++MA + + G Sbjct: 58 SLRRKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEG 117 Query: 84 RSIARALSAWRGWYQWL 100 S+A A+ + G ++ L Sbjct: 118 HSLADAMKCFPGSFERL 134
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 29.1 bits (65), Expect = 0.015 Identities = 12/49 (24%), Positives = 21/49 (42%), Gaps = 4/49 (8%) Query: 62 LVRHGNENDRTQQRIHAWTARLLGEADAHAL----PYTVQDGLREIFEV 106 L R +E R R+ R++ E AH L ++ G+ + E+ Sbjct: 487 LFRRKSELTRRTVRLFIIEPRIIDEGIAHHLALGNGQDLRTGILTVDEI 535
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 30.8 bits (69), Expect = 0.013 Identities = 27/87 (31%), Positives = 45/87 (51%), Gaps = 5/87 (5%) Query: 394 NTAKKDVFPAMWAGEHGGDADAIIAEKGLK--QMSDSGELEKIIDEVLAANAKSVEEFRA 451 N+ K ++F A+ E DA AI + LK + S +LE + ++ L KS +EF+ Sbjct: 649 NSQKDEIF-ALINKEANRDARAIAYAQNLKGIKRELSDKLENV-NKNLKDFDKSFDEFKN 706 Query: 452 GKDKAFNALVGQAMKATRGKANPSQVN 478 GK+K F+ + +KA +G +N Sbjct: 707 GKNKDFSK-AEETLKALKGSVKDLGIN 732
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 511 bits (1318), Expect = 0.0 Identities = 251/348 (72%), Positives = 296/348 (85%), Gaps = 2/348 (0%) Query: 1 MFGFLRSYFSNDLAIDLGTANTLIYVRDKGIVLDEPSVVAIRQEGGPNAKKTIQAVGKEA 60 M R FSNDL+IDLGTANTLIYV+ +GIVL+EPSVVAIRQ+ + K++ AVG +A Sbjct: 1 MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRA-GSPKSVAAVGHDA 59 Query: 61 KQMLGKVPGNIEAIRPMKDGVIADFTVTEQMLKQFIKMVHDSKLLRPSPRIIICVPCGST 120 KQMLG+ PGNI AIRPMKDGVIADF VTE+ML+ FIK VH + +RPSPR+++CVP G+T Sbjct: 60 KQMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGAT 119 Query: 121 QVERRAIRESALGAGASQVYLIEEPMAAAIGAGLPVSEPSGSMVVDIGGGTTEVGIISLG 180 QVERRAIRESA GAGA +V+LIEEPMAAAIGAGLPVSE +GSMVVDIGGGTTEV +ISL Sbjct: 120 QVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLN 179 Query: 181 GMVYKGSVRVGGDKFDEAIVNYIRRNYGMLIGEQTAEAIKKEIGSAFPGSEVREMEVKGR 240 G+VY SVR+GGD+FDEAI+NY+RRNYG LIGE TAE IK EIGSA+PG EVRE+EV+GR Sbjct: 180 GVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGR 239 Query: 241 NLSEGIPRAFTVSSNEILEALTDPLNQIVSSVKIALEQTPPELGADIAERGMMLTGGGAL 300 NL+EG+PR FT++SNEILEAL +PL IVS+V +ALEQ PPEL +DI+ERGM+LTGGGAL Sbjct: 240 NLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGAL 299 Query: 301 LRDLDRLLAEETGLPVLVAEDPLTCVVRGSGMALERMDKL-GSIFSYE 347 LR+LDRLL EETG+PV+VAEDPLTCV RG G ALE +D G +FS E Sbjct: 300 LRNLDRLLMEETGIPVVVAEDPLTCVARGGGKALEMIDMHGGDLFSEE 347
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 76.6 bits (188), Expect = 7e-19 Identities = 53/191 (27%), Positives = 78/191 (40%), Gaps = 1/191 (0%) Query: 2 KNILIVGATSAIAIACARQWAAEGARFFLVARNGERLEQVADDLSARGAQLASRHQLDIT 61 K I GA I A AR A++GA V N E+LE+V L A A+ A D+ Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAE-ARHAEAFPADVR 67 Query: 62 DLERHAAMFEQCLAALGTIDIVLVAPGTLPDQAACQADPAIAVREFNTNATAVIALLTRI 121 D + + +G IDI++ G L F+ N+T V + Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 122 ANALEAQRSGALAVISSVAADRGRPSNYLYGSAKAALSAFCEGLNARLFKAGVHVLTIKP 181 + + +RSG++ + S A R S Y S+KAA F + L L + + + P Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 182 GFVSTPMTAGL 192 G T M L Sbjct: 188 GSTETDMQWSL 198
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 64.3 bits (156), Expect = 3e-14 Identities = 53/195 (27%), Positives = 89/195 (45%), Gaps = 10/195 (5%) Query: 3 QIVFITGASSGIGQALARQYAARGATLGLVARRVDALHGFVQTLPA-GIAVHCYAADVRD 61 +I FITGA+ GIG+A+AR A++GA + V + L V +L A + ADVRD Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 62 ARSMHDAASAFMAVAGVPDVVIANAGISVGTDLREAGDLPAFAAVMETNWMGVLHTLQPF 121 + ++ + + G D+++ AG+ + D + A N GV + + Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSD-EEWEATFSVNSTGVFNASRSV 127 Query: 122 VGPMLARAEPGRPGGTLVGIASVAGVRGLPGAAAYSASKAAVIKLMESLRVEFSPKRRPG 181 M+ R G++V + S AAY++SKAA + + L +E + Sbjct: 128 SKYMMDRR-----SGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEY---N 179 Query: 182 LRVVTLAPGYIRTPM 196 +R ++PG T M Sbjct: 180 IRCNIVSPGSTETDM 194
>PERTACTIN#Pertactin signature. Length = 922 Score = 33.5 bits (76), Expect = 6e-04 Identities = 34/97 (35%), Positives = 41/97 (42%), Gaps = 9/97 (9%) Query: 81 ADPNAPLWSRVPAKPVDQVPEPNQPGTQPGTQPASQATPKPAEPGSSVAMQRPPKPVTPA 140 A+ N WS V AK QPG QPG QP P+P +P +PP+ A Sbjct: 554 ANGNG-QWSLVGAKAPPAPKPAPQPGPQPGPQP-----PQPPQPPQPPQPPQPPQRQPEA 607 Query: 141 PAEKPVADPIAEIARQDAAKTGYFLQVGAYDSAEYAE 177 PA +P A A A TG VG + YAE Sbjct: 608 PAPQPPAGRELSAAANAAVNTG---GVGLASTLWYAE 641
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 631 bits (1629), Expect = 0.0 Identities = 220/580 (37%), Positives = 331/580 (57%), Gaps = 14/580 (2%) Query: 1 MPFTLHGIPVSRGIAIGRAHMLARAALDVSHYLVDEDKLDAEVERLRAARTAVRAELVLL 60 M + GI S G+AI +A + +D+ + + + E+E+L AA + EL + Sbjct: 1 MHHKITGIAASSGVAIAKAFIHLEPNVDIEKTSITD--VSTEIEKLTAALEKSKEELRAI 58 Query: 61 KRELPTDAPEEMGAFLDVHRMILDDALLAQAPETLIHQRRYNAEWALTTQLEELMRQFGE 120 K + + H ++LDD L + I + NAE+AL + + F Sbjct: 59 KDQTEASMGADKAEIFAAHLLVLDDPELVDGIKGKIENEQMNAEYALKEVSDMFVSMFES 118 Query: 121 IEDEYLRERKADIEQVVERILKALAGTPVLAPAPVAAGGDPDAGMIVVAHDIAPADMLQF 180 +++EY++ER ADI V +R+L L G + A + +++A D+ P+D Q Sbjct: 119 MDNEYMKERAADIRDVSKRVLGHLIGVETGSLATI------AEETVIIAEDLTPSDTAQL 172 Query: 181 RGQTFAGFVTDLGGRTSHTAIVARSLDIPAAVGVHNASTLIRQDDRIIIDGDNGIVIVDP 240 Q GF TD+GGRTSH+AI++RSL+IPA VG + I+ D +I+DG GIVIV+P Sbjct: 173 NKQFVKGFATDIGGRTSHSAIMSRSLEIPAVVGTKEVTEKIQHGDMVIVDGIEGIVIVNP 232 Query: 241 SLAILEEYRHRRSESELQKKRLERLRHTPTVTLDGTQIDLLANIEMPEDAAAALAAGAVG 300 + ++ Y +R+ E QK+ +L P+ T DG ++L ANI P+D LA G G Sbjct: 233 TEEEVKAYEEKRAAFEKQKQEWAKLVGEPSTTKDGAHVELAANIGTPKDVDGVLANGGEG 292 Query: 301 VGLFRSEFLFMNRRGALPDEEEQFAAYRTAVESMNGLPVTIRTIDIGADKPLDVRDGRDD 360 +GL+R+EFL+M+R LP EEEQF AY+ V+ M+G PV IRT+DIG DK L + Sbjct: 293 IGLYRTEFLYMDR-DQLPTEEEQFEAYKEVVQRMDGKPVVIRTLDIGGDKELSYLQLPKE 351 Query: 361 LFETAPNPALGLRAIRWSLSEPAMFLTQLRALLRASAFGPVRMLVPMLAHAREIDQTLEL 420 L NP LG RAIR L + +F TQLRALLRAS +G ++++ PM+A E+ Q + Sbjct: 352 L-----NPFLGFRAIRLCLEKQDIFRTQLRALLRASTYGNLKVMFPMIATLEELRQAKAI 406 Query: 421 IERAKASLDADGMAYDPTIKVGAMIEIPAAVLILPVFLRRMDFLSIGTNDLIQYTLAIDR 480 ++ K L ++G+ +I+VG M+EIP+ + +F + +DF SIGTNDLIQYT+A DR Sbjct: 407 MQEEKDKLLSEGVDVSDSIEVGIMVEIPSTAVAANLFAKEVDFFSIGTNDLIQYTMAADR 466 Query: 481 ADNAVAHLYDPLHPAVLQLIARTIQEGQRAGRPVSVCGEMAGDATMTRLLLGMGLTEFSM 540 + V++LY P HPA+L+L+ I+ G+ V +CGEMAGD LLLG+GL EFSM Sbjct: 467 MNERVSYLYQPYHPAILRLVDMVIKAAHSEGKWVGMCGEMAGDEVAIPLLLGLGLDEFSM 526 Query: 541 HPSQLLSVKQQILRADRPRLMREVDRLLHACEPTEVQDVL 580 + +L + Q+L+ + L + L EV+ ++ Sbjct: 527 SATSILPARSQLLKLSKEELKPFAQKALMLDTAEEVEQLV 566
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 33.7 bits (77), Expect = 1e-04 Identities = 21/103 (20%), Positives = 42/103 (40%), Gaps = 10/103 (9%) Query: 44 EYKESIGEMKHADRLIERILMLDGLPN--LQDLGKLL------IGQDTKEMLECDLKLEK 95 E + E D + ER+L + G P +++ + EM++ + K Sbjct: 52 ELYDHAAE--TVDTIAERLLAIGGQPVATVKEYTEHASITDGGNETSASEMVQALVNDYK 109 Query: 96 AAHATVVEAIAYCEEVKDYVSRTLFVDILDDTEEHIDWLETQL 138 + I EE +D + LFV ++++ E+ + L + L Sbjct: 110 QISSESKFVIGLAEENQDNATADLFVGLIEEVEKQVWMLSSYL 152
>PF05272#Virulence-associated E family protein Length = 892 Score = 35.0 bits (80), Expect = 2e-04 Identities = 28/135 (20%), Positives = 47/135 (34%), Gaps = 18/135 (13%) Query: 41 AAALPYLAAAGIGTLTIVDDDSVDLTNLQRQIIHTTESVGHPKVESARQAIARLNPEVRV 100 A P+ A G + D D + L + + TT G ++ QAI RV Sbjct: 481 VRAFPWRKAPG----PLEDADVLRLAD----YVETTYGTGEASAQTTEQAINVAADMNRV 532 Query: 101 HAVRQRLDA---DGIGALLDGVTVVLDCSDNFATRQATNQACVRARVPLVSGAA------ 151 H R + A D + L + VL + + + + + L+ A Sbjct: 533 HPFRDWVKAQQWDEVPRLEKWLVHVLGKTPDDYKPRRLRYLQLVGKYILMGHVARVMEPG 592 Query: 152 IRFDGQISVFDSRTG 166 +FD + V + G Sbjct: 593 CKFDYSV-VLEGTGG 606
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 29.6 bits (66), Expect = 0.033 Identities = 21/57 (36%), Positives = 26/57 (45%), Gaps = 6/57 (10%) Query: 479 LEAAAAVPDKATKSPAAKESSAPAKLPKGKAAPASEPAAPSGP--ASGVIPAPEPTG 533 LEA A KA K AK++ AKL GKA+ + P A G G AP+ Sbjct: 437 LEAEA----KALKEKLAKQAEELAKLRAGKASDSQTPDAKPGNKAVPGKGQAPQAGT 489
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 28.2 bits (63), Expect = 0.011 Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 8/62 (12%) Query: 83 SKAAGLAKNKETPIILVC------QTGQRAGRAQAVLKQAGYSEVYSLEGGLAAWQQAGL 136 + + + +P +LVC Q +RA R A + AG EV+ +E +AA AGL Sbjct: 96 KQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESA--QGAGAREVFLIEEPMAAAIGAGL 153 Query: 137 PI 138 P+ Sbjct: 154 PV 155
>SECBCHAPRONE#Bacterial protein-transport SecB chaperone protein signature. Length = 170 Score = 151 bits (383), Expect = 2e-49 Identities = 53/160 (33%), Positives = 85/160 (53%), Gaps = 5/160 (3%) Query: 1 MSDQQQQQPGQ---DGQPFFNIQRVYLKDLSLEQPNSPHIFLEQEQPTVEVQVDVAATQL 57 MS++ Q QP IQR+Y+KD+S E PN PHIF + +P + + A Q+ Sbjct: 1 MSEENQVNAADTQATQQPVLQIQRIYVKDVSFEAPNLPHIFQQDWEPKLSFDLSTEAKQV 60 Query: 58 AEGVFEVTVIGTVTTKVK--EKVAFLVEAKQAGIFDIRNVPVEQMDPLLGIACPTIVYPY 115 + ++EV + +V T ++ VAF+ E KQAG+F I + QM L CP +++PY Sbjct: 61 GDDLYEVCLNISVETTMESSGDVAFICEVKQAGVFTISGLEEMQMAHCLTSQCPNMLFPY 120 Query: 116 LRSNIADTIGRAGFQPIHLAEINFQALYEQRLASAMEEAQ 155 R ++ + R F ++L+ +NF AL+ L + Q Sbjct: 121 ARELVSSLVNRGTFPALNLSPVNFDALFMDYLQRQEQAEQ 160
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 83.0 bits (205), Expect = 2e-20 Identities = 37/118 (31%), Positives = 60/118 (50%), Gaps = 1/118 (0%) Query: 2 RIALLEDDPFQSEVIAQILSQSGHDVVTFTNGATLLRMLGRSSYDMLVLDWHTPGMLGID 61 I + +DD V+ Q LS++G+DV +N ATL R + D++V D P D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 LLSVVRSRHQEVLPILFVTAEARERGLVRALGQGADDYITKPFHIPELRARVEALLRR 119 LL ++ + LP+L ++A+ ++A +GA DY+ KPF + EL + L Sbjct: 65 LLPRIKKARPD-LPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 38.3 bits (89), Expect = 7e-05 Identities = 45/258 (17%), Positives = 86/258 (33%), Gaps = 28/258 (10%) Query: 84 ALVFGRLGDMIGRKYTFLITILIMGTSTFIVGLLPSYTTIGAAAPVILIMLRLLQGLALG 143 A V G L D GR+ L+++ I+ P +L + R++ G+ G Sbjct: 60 APVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLW--------VLYIGRIVAGIT-G 110 Query: 144 GEYGGAATYVAEHAPHGRRGNYTSWIQTTATLGLFLSLIVILVVRELTGASFEDWGWRIP 203 A Y+A+ R + ++ G+ ++ G + P Sbjct: 111 ATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVL--------GGLMGGFSPHAP 162 Query: 204 FLVSIVL-LATSVYIRLSMSESPAFQKMKAEGKTSKAPLTESFGQWRNLKIVILALVGLT 262 F + L + + ES K E + + +R + + L Sbjct: 163 FFAAAALNGLNFLTGCFLLPES-----HKGERRPLRREALNPLASFR-WARGMTVVAALM 216 Query: 263 AGQAVVWYTGQFYA---LFFLTQVLKVDAFTANVLIAVALAIGTPF-FVFFGSLSDRIGR 318 A ++ GQ A + F DA T + +A + + + G ++ R+G Sbjct: 217 AVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGE 276 Query: 319 KGIIMAGCLLAVLTYFPL 336 + +M G + Y L Sbjct: 277 RRALMLGMIADGTGYILL 294
>PF06580#Sensor histidine kinase Length = 349 Score = 36.8 bits (85), Expect = 2e-04 Identities = 25/107 (23%), Positives = 41/107 (38%), Gaps = 25/107 (23%) Query: 401 LLDNAIRY----TPDGGHVTVRVTTAPFEPFVFLDVEDTGPGIPAGERERVMQRFYRILG 456 L++N I++ P GG + ++ T V L+VE+TG L Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKD--NGTVTLEVENTGSLA---------------LK 305 Query: 457 TQAEGSGLGLAIVREIVQQHGGDIAVLDYVYQSSPRLAGARFRITLP 503 E +G GL VRE +Q G + + S + + +P Sbjct: 306 NTKESTGTGLQNVRERLQMLYGT----EAQIKLSEKQGKVNAMVLIP 348
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 83.9 bits (207), Expect = 2e-21 Identities = 49/180 (27%), Positives = 81/180 (45%), Gaps = 4/180 (2%) Query: 2 IVFVTGATAGFGAAVARRFVREGHRVIAA---GRRQDRLDALKAELGDALLPFLLDVQDA 58 I F+TGA G G AVAR +G + A + +++ + F DV+D+ Sbjct: 10 IAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDS 69 Query: 59 AAVAALPGALPEGWREVDVLVNNAGLALGLEPAHRASLSDWDLMIGTNVTGLVHVTRALL 118 AA+ + + +D+LVN AG+ L H S +W+ N TG+ + +R++ Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGV-LRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 119 PGMVARNRGHVINLGSIAGTYPYPGGNVYGGTKAFVRQFSLNLRADLTGTRVRVSNVEPG 178 M+ R G ++ +GS P Y +KA F+ L +L +R + V PG Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188
>PF04335#VirB8 type IV secretion protein Length = 227 Score = 29.8 bits (67), Expect = 0.003 Identities = 18/83 (21%), Positives = 33/83 (39%), Gaps = 9/83 (10%) Query: 27 LVLLVIFMVAAPVVNPGVVNLPSVANATPQQTQPPIVVTI---KGDGTILARVKSGSGAT 83 V+ + A + +VA TP +T P V+T+ G+ +I A++ + T Sbjct: 36 WVVAGVAGALA------TAGVVAVAALTPLKTVEPYVITVDRNTGEASIAAKLHGDATIT 89 Query: 84 EQKLANNQELRAFVKQRTGENPD 106 + L +V+ R G Sbjct: 90 YDEAVRKYFLATYVRYREGWIAA 112
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 57.0 bits (137), Expect = 6e-11 Identities = 27/183 (14%), Positives = 56/183 (30%), Gaps = 19/183 (10%) Query: 60 QQAVQSAPAPEPKPEPAVQAPPAKVEEEADIALEQQKRKREEEAAAAREAELARRATAER 119 +V S + + A PPA + K+E + E + Sbjct: 1007 VPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQD--------- 1057 Query: 120 EDAKRQALLKEQKAQQARQAELQKRALAEQLAQQAKERQAHEKAVAAEAQARKDAQLKAQ 179 E AQ A+ K + + E + ++ A ++ + Sbjct: 1058 --------ATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKE 1109 Query: 180 AEAKAKAE--AEARQKAKAVAEAKAKADAEQRAAQARSNAQRQARLRDLQALAGTAGATG 237 +AK + E E + V+ + +++ Q A+ +++ Q+ T T Sbjct: 1110 EKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTE 1169 Query: 238 AAA 240 A Sbjct: 1170 QPA 1172 Score = 39.3 bits (91), Expect = 2e-05 Identities = 25/184 (13%), Positives = 64/184 (34%), Gaps = 16/184 (8%) Query: 49 EEAELWDEAALQQA-VQSAPAPEPKPEPAVQAPPAKVEEEADIALEQQKRKREEEAAAAR 107 +EA+ +A Q V + + + + A VE+E A + ++ +E ++ Sbjct: 1070 KEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEK-AKVETEKTQEVPKVTSQ 1128 Query: 108 EAELARRATAEREDAKRQA------LLKEQKAQQARQAELQK------RALAEQLAQQAK 155 + ++ + A+ +KE ++Q A+ ++ + + + + Sbjct: 1129 VSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTT 1188 Query: 156 ERQAHEKAVAAEAQARKDAQLKAQAEAKAKAEAEARQKAKAVAEAK--AKADAEQRAAQA 213 + E Q +E+ K + R+ ++V A + R+ A Sbjct: 1189 VNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVA 1248 Query: 214 RSNA 217 + Sbjct: 1249 LCDL 1252 Score = 35.4 bits (81), Expect = 4e-04 Identities = 21/175 (12%), Positives = 50/175 (28%), Gaps = 10/175 (5%) Query: 51 AELWDEAALQQAVQSAPAPEPKPEPAVQAPPAKVEEEADIALEQQKRKREEEAAAAREAE 110 +++ + + VQ P + +P V + + EQ ++ Sbjct: 1127 SQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTES 1186 Query: 111 LARRATAEREDAKRQALLKEQKAQQARQAELQKRALAEQLAQQAKERQAHEKAVAAEAQA 170 + Q +E + + + ++ V + Sbjct: 1187 TTVNTGNSVVENPENTT--PATTQPTVNSESSNKP----KNRHRRSVRSVPHNVEPATTS 1240 Query: 171 RKDAQLKAQAEAKAK----AEAEARQKAKAVAEAKAKADAEQRAAQARSNAQRQA 221 D A + + ++AR KA+ VA KA ++ + +N + Sbjct: 1241 SNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHISQLEMNNEGQYN 1295 Score = 33.9 bits (77), Expect = 0.001 Identities = 31/213 (14%), Positives = 61/213 (28%), Gaps = 13/213 (6%) Query: 60 QQAVQSAPAPEPKPEPAVQAPPAKVEEEADIALEQQKRKREEEAAAAREAELARRATAER 119 + A ++ + + A +E ++ E+E A E E + Sbjct: 1067 EVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETE------KTQ 1120 Query: 120 EDAKRQALLKEQKAQQARQAELQKRALAEQ---LAQQAKERQAHEKAVAAEAQARKDAQL 176 E K + + +Q + +Q +A + KE Q+ A Q K+ Sbjct: 1121 EVPKVTS---QVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSS 1177 Query: 177 KAQAEAKAKAEAEARQKAKAVAEAKAKADAEQRAAQARSNAQRQARLRDLQALAGTAGAT 236 + E A + SN + R ++++ Sbjct: 1178 NVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPA 1237 Query: 237 GAAAGSGGGVGSGTGAGGTASAGYADRVRAKVQ 269 ++ V +A +D RAK Q Sbjct: 1238 TTSSNDRSTVALCDLTSTNTNAVLSD-ARAKAQ 1269
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 105 bits (264), Expect = 7e-30 Identities = 37/145 (25%), Positives = 61/145 (42%), Gaps = 17/145 (11%) Query: 37 GGAAAGADTRNVTPVDVSRDELTDPNSPLAKRSVYFDFDSYTVKPEYQGLLTQHARYLQS 96 G AA +V T + V F+F+ T+KPE Q L Q L + Sbjct: 194 GEAAPVVAPAPAPAPEVQTKHFTLKSD------VLFNFNKATLKPEGQAALDQLYSQLSN 247 Query: 97 HN--QRKVLIQGNTDERGTSEYNLALGQKRAEAVRRALSSLGVPDSQMESVSLGKEKPQA 154 + V++ G TD G+ YN L ++RA++V L S G+P ++ + +G+ P Sbjct: 248 LDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPADKISARGMGESNPVT 307 Query: 155 SGHDE---------ESWAQNRRSDI 170 + + A +RR +I Sbjct: 308 GNTCDNVKQRAALIDCLAPDRRVEI 332
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 73.0 bits (179), Expect = 3e-15 Identities = 64/279 (22%), Positives = 100/279 (35%), Gaps = 80/279 (28%) Query: 471 VMGHVDHGKTSLLDYIRRAKVAAGEAG------------------GITQHIGAYHVETPR 512 V+ HVD GKT+L + + A E G GIT G + Sbjct: 8 VLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWEN 67 Query: 513 GVITFLDTPGHEAFTAMRARGAKATDIVILVVAADDGVMPQTKEAIAHAKAAGVPIVVAI 572 + +DTPGH F A R D IL+++A DGV QT+ + G+P + I Sbjct: 68 TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFI 127 Query: 573 NKIDKPEANPDRVKQEL---VSESVIP--------------------------------E 597 NKID+ + V Q++ +S ++ E Sbjct: 128 NKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGNDDLLE 187 Query: 598 EY-GGDSP-----------------FVPV---SAKTGQGIENLLENV--LLQAEVLELKA 634 +Y G S PV SAK GI+NL+E + + ++ Sbjct: 188 KYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSSTHRGQS 247 Query: 635 PINAAAKGLVVEAQLDKGKGPIATVLVQSGTLKRGDVVL 673 + G V + + + + +A + + SG L D V Sbjct: 248 EL----CGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVR 282
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 128 bits (324), Expect = 2e-34 Identities = 84/402 (20%), Positives = 163/402 (40%), Gaps = 22/402 (5%) Query: 24 LSLATFMNVLDSSIANVSIPAISGDLGVAPNQGTWVITSFAVANAISVPLTGWLTQRFGQ 83 L + +F +VL+ + NVS+P I+ D P WV T+F + +I + G L+ + G Sbjct: 19 LCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGI 78 Query: 84 VRLFVTSILLFVLSSWACGLAPNMGT-LIAARILQGAVAGPMIPLSQSLLLSTYPPAKSS 142 RL + I++ S + + + LI AR +QGA A L ++ P Sbjct: 79 KRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRG 138 Query: 143 MALALWGMTTLVAPIMGPIFGGWISDNMTWPWIFYINIPVGILAAYATWVIYKDRESPTR 202 A L G + +GP GG I+ + W ++ IP+ I +++ ++ Sbjct: 139 KAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLL--LIPM-ITIITVPFLMKLLKKEVRI 195 Query: 203 ALPIDRIGLALLVIWVGSLQLMLDRGKELDWFNSAEIVTLTVVAVVGFAFFLVWELTEDH 262 D G+ L+ + + L F ++ ++ +V+V+ F F+ Sbjct: 196 KGHFDIKGIILMSVGIVFFML----------FTTSYSISFLIVSVLSFLIFVKHIRKVTD 245 Query: 263 PVVDLTLFKGRNFSAGVVAISVAYGLFFGNLVILPLWLQTIVGYTATDAG-LVMAPVGIF 321 P VD L K F GV+ + +G G + ++P ++ + + + G +++ P + Sbjct: 246 PFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMS 305 Query: 322 AILLSPVIGKNLPKMDARWVATTAFITFALVFW---MRSRFTIQVDTWTLMVPTLIQGAA 378 I+ + G + + +V ++ F T T ++ L + Sbjct: 306 VIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVF-VLGGLSF 364 Query: 379 MAMFFIPLTSIILSGLRPERIPAASGLSNFVRIMFGGIGASI 420 +++I+ S L+ + A L NF + G G +I Sbjct: 365 TKTV---ISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAI 403
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 79.1 bits (195), Expect = 4e-18 Identities = 52/281 (18%), Positives = 102/281 (36%), Gaps = 26/281 (9%) Query: 92 QLVTAGQPLIELDRADARVALEQAEAALAQAVRQVRTLYSNTGAYTSTLAMRESDLAKAK 151 + V LI+ + + Q E L + + T+ + Y + + +S L Sbjct: 182 EEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFS 241 Query: 152 EDLARRKQIAGTGAVSQE--------EIAHAQTSLQAAEAAVETAREQLQANRVLTEQTT 203 L ++ IA + QE E+ ++ L+ E+ + +A+E+ Q L + Sbjct: 242 S-LLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEI 300 Query: 204 LER----HPNVLQAAAKVREAYLAYARTSLPASVTGYVAKRSVQ-VGQRVAPGTPLMAIV 258 L++ N+ ++ + + + A V+ V + V G V LM IV Sbjct: 301 LDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIV 360 Query: 259 PLDQ-LWVDANFKEVQVRHMRVGQPVELVADVYGSSVTYH--GKVVGFSAGTGSAFSLLP 315 P D L V A + + + VGQ + + + + + GKV + Sbjct: 361 PEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDA-------I 413 Query: 316 AQNATGNWIKVVQRLPVRVSLDPKELKDHPLRVGLSMEARV 356 G V+ + K+ PL G+++ A + Sbjct: 414 EDQRLGLVFNVIISIEENCLST--GNKNIPLSSGMAVTAEI 452 Score = 52.5 bits (126), Expect = 1e-09 Identities = 34/212 (16%), Positives = 69/212 (32%), Gaps = 35/212 (16%) Query: 38 LAAALVVAGVGYGLYWGLYGRWFESTDDAYVQGNVV------QVTPQVAGTVVAIRADDT 91 L A ++ + + G+ E A G + ++ P V I + Sbjct: 59 LVAYFIMGFLVIAFILSVLGQ-VEIV--ATANGKLTHSGRSKEIKPIENSIVKEIIVKEG 115 Query: 92 QLVTAGQPLIELDRADARVALEQAEAALAQA-VRQVRTLYSNTGAYTSTL---------- 140 + V G L++L A + +++L QA + Q R + + L Sbjct: 116 ESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPY 175 Query: 141 --------AMRESDLAKAKEDLARR----KQIAGTGAVSQEEIAHAQTSLQAAEAAVETA 188 +R + L K + + K++ ++ A+ + E Sbjct: 176 FQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLAR--INRYENLSRVE 233 Query: 189 REQLQANRVLTEQTTLERHPNVLQAAAKVREA 220 + +L L + + +H VL+ K EA Sbjct: 234 KSRLDDFSSLLHKQAIAKH-AVLEQENKYVEA 264
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 162 bits (412), Expect = 6e-45 Identities = 98/445 (22%), Positives = 171/445 (38%), Gaps = 82/445 (18%) Query: 4 LRNIAIIAHVDHGKTTLVDQLLRQAGTFRENEQIAE--RVMDSNDIEKERGITILAKNCA 61 + NI ++AHVD GKTTL + LL +G E + + D+ +E++RGITI + Sbjct: 3 IINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITS 62 Query: 62 VEYNGTHINIVDTPGHADFGGEVERVLSMVDGVLLLVDAVEGPMPQTRFVTRKALALGLK 121 ++ T +NI+DTPGH DF EV R LS++DG +LL+ A +G QTR + +G+ Sbjct: 63 FQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIP 122 Query: 122 PIVVINKVDRPGAR-------------PEWVINQTFDLFDK---------------LGAN 153 I INK+D+ G E VI Q +L+ + N Sbjct: 123 TIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGN 182 Query: 154 DDQLD--------------------------FPVVYASGLNGYAGLTDDVRSGDMKPLFE 187 DD L+ FPV + S N + L E Sbjct: 183 DDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIG----------IDNLIE 232 Query: 188 TILDKVPQRNDDPNGSFQLQIISLDYSSYVGKIGVGRITRGRVRPLQDVVVKFGPEGAPI 247 I +K ++ ++YS ++ R+ G + L+D V E Sbjct: 233 VITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH-LRDSVRISEKE---- 287 Query: 248 KGRVNQVLKFRGLERELVQEAEAGDIVLINGIDELGIGCTVCAPDAQDALPMLKVDEPTL 307 K ++ ++ E + +A +G+IV++ + L + + ++ P L Sbjct: 288 KIKITEMYTSINGELCKIDKAYSGEIVILQN-EFLKLNSVLGDTKLLPQRERIENPLPLL 346 Query: 308 TMNFCVNTSPLAGREGKFVTSRQLRDRLDRELKSNVALRVKDTGDDTIFEVSGRGELHLT 367 + + D L + V + I +S G++ + Sbjct: 347 QTTVEPSKPQQREMLLDALLEISDSDPL-------LRYYVDSATHEII--LSFLGKVQME 397 Query: 368 ILVENMRRE-GYELAVSRPRVVFKE 391 + ++ + E+ + P V++ E Sbjct: 398 VTCALLQEKYHVEIEIKEPTVIYME 422
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 30.4 bits (68), Expect = 0.025 Identities = 21/118 (17%), Positives = 41/118 (34%), Gaps = 1/118 (0%) Query: 524 LRQAAAKRAAASTPAAAGTGDAAPAVNRRDQKREEAE-QRQRLAARRKPLQKDVDTVEKR 582 + +A A A ++ E A +A+ K L+ + +E R Sbjct: 202 AMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEAR 261 Query: 583 MAPLQQEKTALEAFLADGAAYEDTNKARLMESLRRQAEVNTELDQLEARWLALQEQLE 640 A L++ F +A T +A +A++ + L A +L+ L+ Sbjct: 262 QAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLD 319
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 45.9 bits (109), Expect = 9e-08 Identities = 35/167 (20%), Positives = 59/167 (35%), Gaps = 31/167 (18%) Query: 93 LLIPMVQSAEEARAAVATMRYPPHGNRGVGSALARASRWNRVDDYVRRADAEMCTLVQVE 152 ++ PM+ + EE R A A M+ G ++ + + VE Sbjct: 389 VMFPMIATLEELRQAKAIMQEEKDKLLSEGVDVSDSIEVG----------------IMVE 432 Query: 153 TPRGVEHLDAILAVAGVDGVFIGPGDLA----------ASMGHLGEPGHPEVRQTIDRTI 202 P + VD IG DL + +L +P HP + + +D I Sbjct: 433 IPSTAVAANLFAKE--VDFFSIGTNDLIQYTMAADRMNERVSYLYQPYHPAILRLVDMVI 490 Query: 203 RRIVAAGKAAGI---LSADPALARHYLSLGATFVAVGSDVTLLARSA 246 + + GK G+ ++ D L LG ++ + L ARS Sbjct: 491 KAAHSEGKWVGMCGEMAGDEVAIPLLLGLGLDEFSMSATSILPARSQ 537
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 30.5 bits (68), Expect = 0.007 Identities = 47/181 (25%), Positives = 73/181 (40%), Gaps = 38/181 (20%) Query: 49 LAELEAAGYASLFTGQKTYNGVAILARKAAMPEGRDVVRNIPDFADEQQRVVAATYDVAG 108 LA++E G K YNG+A + +K G V PD +E+ VAAT D Sbjct: 25 LAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGD--- 81 Query: 109 GPVRVISAYFPNGQALDS-------------DKMVYKMRWLAALQDWLQAEMAAHP---- 151 GP + A+ G S DK+ Y W A + ++ A+P Sbjct: 82 GPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKL-YPFTWDAVRYN---GKLIAYPIAVE 137 Query: 152 RLMLLGDFNIAPDDRDVHDPKKWEGMNLVSPEERAAFRALESAGLVDAFRMFEQEDKLFS 211 L L+ + ++ P+ PK WE E A + L++ G + MF ++ F+ Sbjct: 138 ALSLIYNKDLLPN-----PPKTWE-------EIPALDKELKAKG--KSALMFNLQEPYFT 183 Query: 212 W 212 W Sbjct: 184 W 184
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 105 bits (264), Expect = 8e-29 Identities = 38/150 (25%), Positives = 68/150 (45%), Gaps = 1/150 (0%) Query: 14 TVFVVDDDEAMRDSLTWLLEGNGYNVRTYRSAEEFLVDDKRGEGVGCLILDVRMQGMSGP 73 T+ V DDD A+R L L GY+VR +A G+G ++ DV M + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDG-DLVVTDVVMPDENAF 63 Query: 74 ELQDRLLAENNRMPIVFVTGHGDVPMAVSTMKKGAVDFIEKPFDESELRELVERMLSKAR 133 +L R+ +P++ ++ A+ +KGA D++ KPFD +EL ++ R L++ + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 134 TEDSAAREQKAANDLLSRLTTREQQVLERI 163 S + L + Q++ + Sbjct: 124 RRPSKLEDDSQDGMPLVGRSAAMQEIYRVL 153
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 30.3 bits (68), Expect = 0.023 Identities = 11/62 (17%), Positives = 19/62 (30%), Gaps = 5/62 (8%) Query: 5 PRPQNSGVRPPIMLSPSHATPEPADPATQPPA-----AAMPVPVPAPELPPEDGVRPNVP 59 PQ P ++ P +P + P P P P P ++ + +V Sbjct: 56 EPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVK 115 Query: 60 RG 61 Sbjct: 116 PV 117
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.2 bits (68), Expect = 0.021 Identities = 12/37 (32%), Positives = 23/37 (62%) Query: 49 VPSPKSGVVKEVKIKVGDAVSEGSLVLLLEEQGATAA 85 + ++ +VKE+ +K G++V +G ++L L GA A Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEAD 135
>PF06580#Sensor histidine kinase Length = 349 Score = 34.1 bits (78), Expect = 0.001 Identities = 14/82 (17%), Positives = 27/82 (32%), Gaps = 17/82 (20%) Query: 345 ILDNLIENARRYGKTHDTGRAEITVSTALQGNEVVLCVADRGAGVPADQLALLTRPFYRL 404 ++ L+EN ++G +I + V L V + G+ Sbjct: 259 LVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLA--------------- 303 Query: 405 ESARSEAKGAGLGMSIVSRILQ 426 ++ + G G+ V LQ Sbjct: 304 --LKNTKESTGTGLQNVRERLQ 323
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 104 bits (262), Expect = 3e-28 Identities = 43/137 (31%), Positives = 71/137 (51%), Gaps = 2/137 (1%) Query: 4 SGHKILVVDDDPRLRDLLRRYLGEQGFTVLVAENATAMNKLWLRERFDLLVLDLMMPGED 63 +G ILV DDD +R +L + L G+ V + NA + + DL+V D++MP E+ Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 64 GLSICRRLRGANDQTPIIMLTAKGEDVDRIVGLEMGADDYLPKPFNPRELIARIHAVL-- 121 + R++ A P+++++A+ + I E GA DYLPKPF+ ELI I L Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 122 RRRGPAEIPGAPSETPE 138 +R P+++ + Sbjct: 122 PKRRPSKLEDDSQDGMP 138
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 55.6 bits (134), Expect = 1e-10 Identities = 39/261 (14%), Positives = 78/261 (29%), Gaps = 59/261 (22%) Query: 104 ATVRKGQVLARLDPTDLALAQQSAQAQLQAAKTDRDLAASDLKRFSELFAKGFIS----- 158 +T + + L+ + + A++ + + S L FS L K I+ Sbjct: 196 STWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVL 255 Query: 159 AAEQQRHQANYDAAQAR-----------------------YDQAVAGYRNQSN------- 188 E + +A + + + + Q+ Sbjct: 256 EQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLT 315 Query: 189 --------QAAYATLEADADGVVTSVDA-EVGQVVTAGQPVVRVAQTAEK-EVVVGIPED 238 + + + A V + G VVT + ++ + + EV + Sbjct: 316 LELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNK 375 Query: 239 QVDALRKSPDVRVKLWADPSRS---LPGKVREIAPAADPVTRT---YTVKITVP------ 286 + + + +K+ A P L GKV+ I A R + V I++ Sbjct: 376 DIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCLST 435 Query: 287 -NPPPDLKLGMTAVATFVRPG 306 N L GM A ++ G Sbjct: 436 GNKNIPLSSGMAVTA-EIKTG 455 Score = 49.4 bits (118), Expect = 1e-08 Identities = 28/169 (16%), Positives = 55/169 (32%), Gaps = 10/169 (5%) Query: 69 AAGTVEFSGDVRPRVESRLGFRVPGKIIARLVDVGATVRKGQVLARLDPTDLALAQQSAQ 128 A G + SG + ++ V +I +V G +VRKG VL +L Q Sbjct: 86 ANGKLTHSGRSK-EIKPIENSIV-KEI---IVKEGESVRKGDVLLKLTALGAEADTLKTQ 140 Query: 129 AQLQAAKTD--RDLAASDLKRFSELFAKGFIS-AAEQQRHQANYDAAQARYDQAVAGYRN 185 + L A+ + R S ++L Q + + + + ++N Sbjct: 141 SSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQN 200 Query: 186 QSNQ--AAYATLEADADGVVTSVDAEVGQVVTAGQPVVRVAQTAEKEVV 232 Q Q A+ V+ ++ + + K+ + Sbjct: 201 QKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAI 249
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 502 bits (1294), Expect = e-163 Identities = 234/1056 (22%), Positives = 438/1056 (41%), Gaps = 71/1056 (6%) Query: 8 LSRWALEHQPLTRFLLVALLLGGIFAYTQLGQDEDPPFTFRAMVVQAFWPGATAEQMSRQ 67 ++ + + L + L++ G A QL + P A+ V A +PGA A+ + Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 68 VTDKIEKALQEVPYAWKIRSYSKPGETL---VTFQLADTSPTKDTQQLWYTVRKKVGDIA 124 VT IE+ + + + S S ++ +TFQ T P Q V+ K+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQS-GTDPDIAQVQ----VQNKLQLAT 115 Query: 125 SSLPTGVRGPY-FNDDFGDVYGSIYALSADGFTYRQ--LNDYADA-IRQQLLRVPNVAKV 180 LP V+ + Y + +D Q ++DY + ++ L R+ V V Sbjct: 116 PLLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDV 175 Query: 181 TLLGDQDEKIYIEFQQAKFAQMGLDINSIANQIAQQNNIGPSGVLVTPTD------NVQI 234 L G Q + I + L + NQ+ QN+ +G L N I Sbjct: 176 QLFGAQYA-MRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASI 234 Query: 235 RLSGQFSDIRDLENLTLRGPGGTSNIRLGDIATIRHGYIDPPRAKMRFNGKEVIGLGISM 294 +F + + +TLR S +RL D+A + G + R NGK GLGI + Sbjct: 235 IAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELG-GENYNVIARINGKPAAGLGIKL 293 Query: 295 AKGGDIIQLGKDLRATVERIRAKLPVGIEMQQVQDQPQSVQHSVGEFVHVLIEAVVIVLA 354 A G + + K ++A + ++ P G+++ D VQ S+ E V L EA+++V Sbjct: 294 ATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFL 353 Query: 355 VSFLSLGLHTKPRLRIDVWPGLVVGLTIPLVLAVTFLFMNIFDIGLHKISLGALIIALGL 414 V +L L ++ L+ + +P+VL TF + F ++ +++ +++A+GL Sbjct: 354 VMYLFLQ---------NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGL 404 Query: 415 LVDDAIIAVEMMVR-KLEEGFSKMEAATFAYTSTAMPMLTGTLITATGFLPVGLARSTVG 473 LVDDAI+ VE + R +E+ EA + + ++ ++ + F+P+ + G Sbjct: 405 LVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTG 464 Query: 474 EYTFGIFAVT-ALALVLSWVAAVVFVPYLGYLLL---HTKSHVGDGGHHELFDTPFYNRF 529 + F++T A+ LS + A++ P L LL + H GG F+T F + Sbjct: 465 AI-YRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSV 523 Query: 530 RGW---VNWCVEYRKTVIVITLAAFVLGVFGFKYVEKQFFPDSSRPELMVELWLPEGASF 586 + V + ++I V F + F P+ + + + LP GA+ Sbjct: 524 NHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQ 583 Query: 587 GQTEAEAKRFE--ALIRQQKSVESVAFFIGSGAPRFYLPLDQILPQTNVAQAIVMPTSLE 644 +T+ + L ++ +VESV G N A V E Sbjct: 584 ERTQKVLDQVTDYYLKNEKANVESVFTVNGFSFSG---------QAQNAGMAFVSLKPWE 634 Query: 645 TR---EDVRQEIIGLLKSQFPQLRGRVKLLPNGPPV-------PYPVQ-FRVMGPDIGGV 693 R E+ + +I K + ++R + N P + + + G + Sbjct: 635 ERNGDENSAEAVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDAL 694 Query: 694 RKIADQVKAIMQANPNTV-GVNDNWNENVKLLRLDIDQDKARALGVTTGSIAQVTQTVMS 752 + +Q+ + +P ++ V N E+ +L++DQ+KA+ALGV+ I Q T + Sbjct: 695 TQARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALG 754 Query: 753 GAPIAQYRDGDKLLDIVMRPQERERNTLDALQNVQVPTASGRVVPLTQVARVGFAWEPGV 812 G + + D ++ + ++ + R + + + V +A+G +VP + + + Sbjct: 755 GTYVNDFIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPR 814 Query: 813 IWRENRDYGITVQSDVVDGVQGPTVTAQINPLLDKIRADLPPDYQIKIAGAEEESANAGA 872 + R N + +Q + G + L++ + + LP G + +G Sbjct: 815 LERYNGLPSMEIQGEAAPGT----SSGDAMALMENLASKLPAGIGYDWTGMSYQERLSGN 870 Query: 873 SIVAQMPLCIFIIFTLLMLQLHSFSRSVMVFLTGPLGLIGAAATLLLLRAPMGFVAQLGI 932 A + + ++F L S+S V V L PLG++G L +G+ Sbjct: 871 QAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGL 930 Query: 933 TALIGMIIRNSVILVDQIEQ-DVATGVPTWTAIVEAAVRRFRPIILTAAAAVLAMIPLSR 991 IG+ +N++++V+ + G A + A R RPI++T+ A +L ++PL+ Sbjct: 931 LTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAI 990 Query: 992 SVFWG-----PMAAAIMGGLIVATVLTLLFLPALYA 1022 S G + +MGG++ AT+L + F+P + Sbjct: 991 SNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFV 1026 Score = 113 bits (284), Expect = 2e-27 Identities = 99/528 (18%), Positives = 186/528 (35%), Gaps = 49/528 (9%) Query: 7 NLSRWALEHQPLTRFLLVALLLGGIFAYTQLGQDEDPPF-TFRAMVVQAFWPGATAEQMS 65 N L + ++ G + + +L P + + GAT E+ Sbjct: 528 NSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQ 587 Query: 66 R---QVTD---KIEKALQEVPYAWKIRSYSKP----GETLVTFQLAD--TSPTKDTQQLW 113 + QVTD K EKA E + S+S G V+ + + + + Sbjct: 588 KVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVI 647 Query: 114 YTVRKKVGDIASSLPTGVRGPYFNDDFGDVYGSIYALSAD-GFTYRQLNDYADAIRQQLL 172 + + ++G I P + G G + L G + L + + Sbjct: 648 HRAKMELGKIRDGFVIPFNMPAI-VELGTATGFDFELIDQAGLGHDALTQARNQLLGMAA 706 Query: 173 RVP-NVAKVTLLGDQDE-KIYIEFQQAKFAQMGLDINSIANQIAQQNNIGPSGVLVTPTD 230 + P ++ V G +D + +E Q K +G+ ++ I I +G + V Sbjct: 707 QHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTI--STALGGTYVNDFIDR 764 Query: 231 ----NVQIRLSGQF-SDIRDLENLTLRGPGGTSNIRLGDIATIRHGYIDPPRAKMRFNGK 285 + ++ +F D++ L +R G + T Y PR + R+NG Sbjct: 765 GRVKKLYVQADAKFRMLPEDVDKLYVRSANGEM-VPFSAFTTSHWVY-GSPRLE-RYNGL 821 Query: 286 EVIGLGISMAKGGDIIQLGKDLRATVERIRAKLPVGIEMQQVQDQPQSVQHSVGEFVHVL 345 + + A G D A +E + +KLP GI + S + ++ Sbjct: 822 PSMEIQGEAAPGTSS----GDAMALMENLASKLPAGIGYD-WTGMSYQERLSGNQAPALV 876 Query: 346 IEAVVIV---LAVSFLSLGLHTKPRLRIDVWPGLVVGLTIPLVLAVTFLFMNIFDIGLHK 402 + V+V LA + S + + V L +PL + L +F+ Sbjct: 877 AISFVVVFLCLAALYESWSI------------PVSVMLVVPLGIVGVLLAATLFNQKNDV 924 Query: 403 ISLGALIIALGLLVDDAIIAVEMMV-RKLEEGFSKMEAATFAYTSTAMPMLTGTLITATG 461 + L+ +GL +AI+ VE +EG +EA A P+L +L G Sbjct: 925 YFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILG 984 Query: 462 FLPVGLARSTVGEYTFGIFAVTALALVLSWVAAVVFVPYLGYLLLHTK 509 LP+ ++ + +V + + A+ FVP ++++ Sbjct: 985 VLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVF-FVVIRRC 1031 Score = 78.3 bits (193), Expect = 1e-16 Identities = 78/515 (15%), Positives = 166/515 (32%), Gaps = 47/515 (9%) Query: 542 TVIVITLAAFVLGVFGFKYVEKQFFPDSSRPELMVELWLPEGASFGQTEAEAKRF--EAL 599 V+ + + G + +P + P + V P GA + + + + Sbjct: 11 FAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYP-GADAQTVQDTVTQVIEQNM 69 Query: 600 --IRQQKSVESVAFFIGSGAPRFYLPLDQILPQTNVAQAIVMPTSLETREDVRQEIIGLL 657 I + S + GS T+ A V V Q + L Sbjct: 70 NGIDNLMYMSSTSDSAGSVTITLTFQSG-----TDPDIAQV---------QV-QNKLQLA 114 Query: 658 KSQFPQ--LRGRVKLLPNGPPVPYPVQFRVMGPDIG-------GVRKIADQVKAIMQANP 708 PQ + + + + F P + D + + Sbjct: 115 TPLLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRL----N 170 Query: 709 NTVGVNDNWNENVKLLRLDIDQDKARALGVTTGSIAQV----TQTVMSGAPIAQYRDGDK 764 V + +R+ +D D +T + + +G + Sbjct: 171 GVGDVQLFGAQ--YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQ 228 Query: 765 LLDIVMRPQERERNTLDALQNVQVPTASGRVVPLTQVARVGFAWEP-GVIWRENRDYGIT 823 L+ + Q R +N + + + G VV L VARV E VI R N Sbjct: 229 QLNASIIAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAG 288 Query: 824 VQSDVVDGVQGPTVTAQINPLLDKIRADLPPDYQIKIAGAEEESANAGASIVAQMPL-CI 882 + + G I L +++ P ++ V + I Sbjct: 289 LGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAI 348 Query: 883 FIIFTLLMLQLHSFSRSVMVFLTGPLGLIGAAATLLLLRAPMGFVAQLGITALIGMIIRN 942 ++F ++ L L + +++ + P+ L+G A L + + G+ IG+++ + Sbjct: 349 MLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDD 408 Query: 943 SVILVDQIEQ-DVATGVPTWTAIVEAAVRRFRPIILTAAAAVLAMIPL-----SRSVFWG 996 ++++V+ +E+ + +P A ++ + ++ A IP+ S + Sbjct: 409 AIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYR 468 Query: 997 PMAAAIMGGLIVATVLTLLFLPALYAAWFRVKRPE 1031 + I+ + ++ ++ L+ PAL A + E Sbjct: 469 QFSITIVSAMALSVLVALILTPALCATLLKPVSAE 503
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 89.3 bits (221), Expect = 2e-23 Identities = 66/258 (25%), Positives = 112/258 (43%), Gaps = 19/258 (7%) Query: 10 IALVTGGSRGLGRNMVQKLARGGTDVIFTYRSNQAEAQALVAELAALGRRAAALQLDAGQ 69 IA +TG ++G+G + + LA G + N + + +V+ L A R A A D Sbjct: 10 IAFITGAAQGIGEAVARTLASQGAHIA-AVDYNPEKLEKVVSSLKAEARHAEAFPADV-- 66 Query: 70 IATFAAFADAVRGVLAQWQRE--RIDALVNNAGIGIHASLAEMTEAQFDALMNVHFKGVF 127 + A+ + A+ +RE ID LVN AG+ + +++ +++A +V+ GVF Sbjct: 67 -----RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVF 121 Query: 128 FLTQALLPLIAD--GGRIVNISSGLTRFAFVGYGAYAAMKGAVEVLTKYMAKELGPRGIA 185 ++++ + D G IV + S AYA+ K A + TK + EL I Sbjct: 122 NASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIR 181 Query: 186 VNVVAPGAIETDFGGGRVRDDANLNAMVAAQTA-------LGRVGLPDDIGGVVASLLAP 238 N+V+PG+ ETD D+ ++ L ++ P DI V L++ Sbjct: 182 CNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSG 241 Query: 239 DNRWINAQRIEASGGMFL 256 I + GG L Sbjct: 242 QAGHITMHNLCVDGGATL 259
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 28.9 bits (64), Expect = 0.045 Identities = 45/179 (25%), Positives = 73/179 (40%), Gaps = 12/179 (6%) Query: 11 STARLKRELKSAEARRRAMALALVAPL----ALFLLLIFVVPIGALLTRAVQNPEVADAL 66 STA+LK+ AR +A A A AL L +V AL A + P + Sbjct: 58 STAQLKKTQAEQAARAKAAAEAQAKAKANRDALTQRLKDIVN-EALRHNASRTPSATELA 116 Query: 67 PRTVAALKSWDRRTPPADAAYAALADDLTATQAGEAMGALARRLNTEISGFRSLVAKTAR 126 AA+++ D R A A A + A +A + A + EI A+T R Sbjct: 117 HANNAAMQAEDERLRLAKAEEKARKEAEAAEKAFQE----AEQRRKEIE---REKAETER 169 Query: 127 AMPLADEQGHALAPAQTRARLVELDERWADTAYWQAIAKNSSRTSPFYLLAALDHRQDA 185 + LA+ + LA A+ VE+ ++ A + + + + L++ H +DA Sbjct: 170 QLKLAEAEEKRLAALSEEAKAVEIAQKKLSAAQSEVVKMDGEIKTLNSRLSSSIHARDA 228
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.011 Identities = 9/31 (29%), Positives = 15/31 (48%) Query: 37 LTLLGPSGSGKTTCLMMLAGFEFPTGGEIRL 67 + L G G GK+T + L G +F + + Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDI 629
>PF06580#Sensor histidine kinase Length = 349 Score = 31.4 bits (71), Expect = 0.008 Identities = 22/106 (20%), Positives = 41/106 (38%), Gaps = 24/106 (22%) Query: 356 LQELVGNLLDNAIRYAGPDARVTLRVARQAAPGQDTGALLQVEDNGPGIAEAERAAVFGR 415 +Q LV N + + I ++ L+ + + L+VE+ G + Sbjct: 260 VQTLVENGIKHGIAQLPQGGKILLKGTKD-----NGTVTLEVENTGSLALK--------- 305 Query: 416 FYRGSTAQAQEGSGLGLAIVRE-IARVHG--ATVALSDTAGGGLTV 458 +E +G GL VRE + ++G A + LS+ G + Sbjct: 306 -------NTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAM 344
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 96.4 bits (240), Expect = 3e-25 Identities = 52/199 (26%), Positives = 86/199 (43%), Gaps = 26/199 (13%) Query: 2 RILLVEDNPKLAGTLEEALGQAGFTVDCVHDGHAADLLLTTQDYALLLLDLGLPRLDGLE 61 IL+ +D+ + L +AL +AG+ V + + D L++ D+ +P + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VLRRLRLRRNPLPVMILTAHGAVEERVRGLNLGADDYLTKPFDLTE-VEARARALIRRSH 120 +L R++ R LPV++++A ++ GA DYL KPFDLTE + RAL Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 121 GHERTQLQCGPLHY-DGTSGAFT-----------------LRGEALALTGRE---RAVLE 159 + + G S A + GE + TG+E RA+ + Sbjct: 125 RPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGE--SGTGKELVARALHD 182 Query: 160 VLMLRDGR--AVNKAAISE 176 R+G A+N AAI Sbjct: 183 YGKRRNGPFVAINMAAIPR 201
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 90.6 bits (225), Expect = 1e-22 Identities = 93/364 (25%), Positives = 141/364 (38%), Gaps = 44/364 (12%) Query: 1 MKITSMALAAAALATAGTAAAQSNVTLYGIMDAGIEYVNHAGANGGGAARLVSGGKNT-- 58 MK + +AL AAL A A +VTLYG + AG+E NG AA + +G Sbjct: 1 MKKSLIALTLAALPVAAMA----DVTLYGTIKAGVETSRSVAHNGAQAASVETGTGIVDL 56 Query: 59 -SRWGLRGSEDLGGGLKGIFNLESGIAIDTGRLDTDNTLFDRRAVVGLAGSFGQVVFGRT 117 S+ G +G EDLG GLK I+ +E TD+ +R++ +GL G FG++ GR Sbjct: 57 GSKIGFKGQEDLGNGLKAIWQVEQKA----SIAGTDSGWGNRQSFIGLKGGFGKLRVGRL 112 Query: 118 FTTTYDF--MLPYDPMGYAPNYSWATSSTATGDRKDGLFSRASNAVRYDGT-FGGLKLGA 174 + D + P+D +Y R VRYD F GL Sbjct: 113 NSVLKDTGDINPWDSKS---DYLGVNKIAEPEARLIS--------VRYDSPEFAGLSGSV 161 Query: 175 TVGFGEVAGNFNSSSKYDVGIGYSAGGFSAAATWDRQNGAGTSTTPADTTDYIQGIHAGA 234 + AG NS S Y G Y GGF + + Q + Sbjct: 162 QYALNDNAGRHNSES-YHAGFNYKNGGFFVQYGGAYKRHH--QVQENVNIEKYQIHRLVS 218 Query: 235 SYDFGALKLF--AGYRNYKRAFTTAAATQRSDMYWAGASYDF---TPAFTLFGAVYKQNI 289 YD AL ++ K + ++++ A +Y F TP + Sbjct: 219 GYDNDALYASVAVQQQDAKLVEENYSHNSQTEVA-ATLAYRFGNVTPRVSYAHGFKGSFD 277 Query: 290 KGGTDADPILFSLRAQYALSKRTTAYLAGGYAKARNGQNVSLSRDVAGFGNSQVGVTAGL 349 + D + A+Y SKRT+A ++ G+ + G++ +S GL Sbjct: 278 ATNYNNDYDQVVVGAEYDFSKRTSALVSAGWLQEGKGESKFVSTAGG----------VGL 327 Query: 350 QHRF 353 +H+F Sbjct: 328 RHKF 331
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 29.9 bits (67), Expect = 0.008 Identities = 14/65 (21%), Positives = 31/65 (47%), Gaps = 11/65 (16%) Query: 6 KMLRRQRGMSLVELMIGMA-LGLLLLTALGSLYFSTTQSRAQLANS----------ASQI 54 + +QRG +L+E+M+ + +G+L + +L + ++ Q A S ++ Sbjct: 2 RATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKL 61 Query: 55 ENGRY 59 +N Y Sbjct: 62 DNHHY 66
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 31.0 bits (70), Expect = 0.001 Identities = 11/24 (45%), Positives = 19/24 (79%), Gaps = 2/24 (8%) Query: 17 QRGLTLIEVLISVVIL--LAALLG 38 QRG TL+E+++ +VI+ LA+L+ Sbjct: 7 QRGFTLLEIMVVIVIIGVLASLVV 30
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 30.6 bits (69), Expect = 0.001 Identities = 13/44 (29%), Positives = 23/44 (52%) Query: 16 RGVTLPELLVGLAVLSILIVIAVPSFSGLIATQRARNASLDLSA 59 RG TL E++V + ++ +L + VP+ G + A D+ A Sbjct: 8 RGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVA 51
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 53.4 bits (128), Expect = 6e-12 Identities = 20/67 (29%), Positives = 37/67 (55%) Query: 8 QRARSARGFTLIELMIVAAIVAILAVLAYPSYVQYVVRSNRAAAESFMQEVAAAQERFLL 67 + RGFTL+E+M+V I+ +LA L P+ + ++++ A S + + A + + L Sbjct: 2 RATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKL 61 Query: 68 DNRAYAS 74 DN Y + Sbjct: 62 DNHHYPT 68
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 30.5 bits (69), Expect = 0.005 Identities = 51/248 (20%), Positives = 79/248 (31%), Gaps = 49/248 (19%) Query: 1 MSVIAANLQAVRQRITTACTLASRDPASVTLLAVSKTFDADA-----VRAAHAAGQ-RLF 54 + + NL VRQ T A + +V K A+A R A G F Sbjct: 11 LQALKQNLSIVRQAATHAR-----------VWSVVK---ANAYGHGIERIWSAIGATDGF 56 Query: 55 GENYVQEGTAKTSALTDLR----NGPEAIAWHFIGPLQSNKTRAVAEHFD-WVHSIDRLK 109 ++E LR GP + F + VHS +LK Sbjct: 57 ALLNLEEAIT-------LRERGWKGPILMLEGFFHA--QDLEIYDQHRLTTCVHSNWQLK 107 Query: 110 IAERLSAQRPATLPPLQVCLEINISRQASKHGVPPDLDEVLPLARAVAALPRLRLRGLMA 169 + + P + L++N ++ G PD VL + + + A+ + LM+ Sbjct: 108 ALQNARLKAPLD-----IYLKVNSG--MNRLGFQPD--RVLTVWQQLRAMANVGEMTLMS 158 Query: 170 VPEPADDPAARRAPFAALRDLADRLCAAGLPVDTLSMGMSADLEDAIAEGATIVRVGSAI 229 A+ P A + A GL +A L A VR G + Sbjct: 159 HFAEAEHPDGISGAMARIEQA-----AEGLECRRSLSNSAATLWHPEA-HFDWVRPGIIL 212 Query: 230 FGARQYAH 237 +GA Sbjct: 213 YGASPSGQ 220
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 30.6 bits (69), Expect = 0.017 Identities = 21/83 (25%), Positives = 36/83 (43%), Gaps = 13/83 (15%) Query: 186 MLNLLLALAMLG-FGVLFFLSQSWL-PFVIMTAIAFAL-GVLIIIPIGGA--DMPVVVSM 240 L+A++ + F L L +SW P +M + + GVL+ + D+ +V + Sbjct: 871 QAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGL 930 Query: 241 LNSYSGWAAAGIGFSLNNPMLII 263 L IG S N +LI+ Sbjct: 931 L--------TTIGLSAKNAILIV 945
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 37.1 bits (86), Expect = 9e-05 Identities = 15/80 (18%), Positives = 31/80 (38%), Gaps = 9/80 (11%) Query: 101 QPSVIVVDYSMPRMNGLEFCAKLK----DLPCMTILLTGMADENIAVQGFNDGLIDRYIK 156 ++V D MP N + ++K DLP ++++ A++ G D Y+ Sbjct: 47 DGDLVVTDVVMPDENAFDLLPRIKKARPDLP--VLVMSAQNTFMTAIKASEKGAYD-YLP 103 Query: 157 K--DHPAMAERLSTEIEALQ 174 K D + + + + Sbjct: 104 KPFDLTELIGIIGRALAEPK 123
>PF06580#Sensor histidine kinase Length = 349 Score = 29.1 bits (65), Expect = 0.037 Identities = 5/35 (14%), Positives = 12/35 (34%) Query: 352 KAQREHPCIDISAEWHNGRLYVVVKDNGPGIAEKN 386 + I + NG + + V++ G + Sbjct: 273 AQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNT 307
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 84.5 bits (209), Expect = 4e-20 Identities = 31/133 (23%), Positives = 56/133 (42%), Gaps = 4/133 (3%) Query: 7 TGPTILYVDDEQQACKWFTRMVS-ASYNVLTANSVEEAKAVLRDAHDRIGVVLTDFRMPG 65 TG TIL DD+ + +S A Y+V ++ + +V+TD MP Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGD--GDLVVTDVVMPD 59 Query: 66 GDGTELLRFIDAEYSDIAAILVTAYADKDLLIQAVNTGRVFKILEKPYQPEDVRRSLQEA 125 + +LL I D+ ++++A I+A G + L KP+ ++ + A Sbjct: 60 ENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKG-AYDYLPKPFDLTELIGIIGRA 118 Query: 126 LALRQDRLLRTQR 138 LA + R + + Sbjct: 119 LAEPKRRPSKLED 131
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 87.2 bits (216), Expect = 4e-21 Identities = 30/135 (22%), Positives = 59/135 (43%), Gaps = 6/135 (4%) Query: 9 PKILYVDDETLALTYFGRAIGSLA-PVLTATSVEEGKRMLDEHAATLGVLVSDQRMPGEL 67 IL DD+ T +A+ V ++ R + A ++V+D MP E Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIA--AGDGDLVVTDVVMPDEN 61 Query: 68 GNELLRYARERYPHMVRILTTAYSEIEDTVEAVNQGQIHRYIKKPWDITALRVELKQALE 127 +LL ++ P + ++ +A + ++A +G + Y+ KP+D+T L + +AL Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKG-AYDYLPKPFDLTELIGIIGRALA 120 Query: 128 FADLRRERDALLREK 142 + +R L + Sbjct: 121 --EPKRRPSKLEDDS 133
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 66.2 bits (161), Expect = 3e-14 Identities = 35/160 (21%), Positives = 58/160 (36%), Gaps = 29/160 (18%) Query: 116 LGSGVIVSPEGYILTNHHVVDGADEIEVALT------------DGRKANAKVVGTDPETD 163 + SGV+V +LTN HVVD AL +G ++ E D Sbjct: 103 IASGVVVGK-DTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEGD 161 Query: 164 LAVLKISLT--------NLPAITLGRLENVRVGDVVLAIGNPFGVGQTVTMGIVSALGRS 215 LA++K S + T+ +V + G P V+ + S Sbjct: 162 LAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGD-------KPVATMWES 214 Query: 216 HLGINTFEN-FIQTDAAINPGNSGGALVDAEGNLLGINTA 254 I + +Q D + GNSG + + + ++GI+ Sbjct: 215 KGKITYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHWG 254
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 92.2 bits (229), Expect = 4e-23 Identities = 89/391 (22%), Positives = 130/391 (33%), Gaps = 72/391 (18%) Query: 1 MKMKLFAAAVAALAAGGAYAQSSVTLYGVADVGVEWANKVPGADGQGHSRVAMQSGNLSG 60 MK L A +AAL + VTLYG GVE + V Q S G Sbjct: 1 MKKSLIALTLAALPVAAM---ADVTLYGTIKAGVETSRSVAHNGAQAASVETGTGIVDLG 57 Query: 61 SRWGLRGVEDLGGGLKGIFNLESGFNLDTGTSAQSSRLFGRNAYVGLQGQWGQLTLGRQQ 120 S+ G +G EDLG GLK I+ +E ++ S +R +++GL+G +G+L +GR Sbjct: 58 SKIGFKGQEDLGNGLKAIWQVEQKASIAGTDSGWGNRQ----SFIGLKGGFGKLRVGRLN 113 Query: 121 NLLYD---FALAYDPMAIAGRYSITAQDAFMAG-RADNAIKYIGTFGGLSVSALYAFNRD 176 ++L D G I +A + R D+ F GLS S YA N + Sbjct: 114 SVLKDTGDINPWDSKSDYLGVNKIAEPEARLISVRYDSP-----EFAGLSGSVQYALNDN 168 Query: 177 GQEVAGVNKLGREWSLGANYAAGPFGLGVVYDQSN---GTAASNASFAAQNAAADTKEQR 233 + G NY G F + N + + Sbjct: 169 AG-----RHNSESYHAGFNYKNGGFFVQYGGAYKRHHQVQENVNIEKYQIHRLVSGYDND 223 Query: 234 ATIAGSYA-FGPAKLYAGYRWYHANFATVAGA----GNLRSNLYWLGAGYQATPALTLTG 288 A A AKL +++ A GN+ + Y + Sbjct: 224 ALYASVAVQQQDAKLVEENYSHNSQTEVAATLAYRFGNVTPRV-----SYAHGFKGSFDA 278 Query: 289 TAYYQQFKNSGTGNPWLFVVGTDYALSKRTDAYFNVAYAKNSNGSTLGVAGINGASSGNA 348 T Y + VVG +Y SKRT A + + + G + V+ Sbjct: 279 TNYNNDYDQ--------VVVGAEYDFSKRTSALVSAGWLQEGKGESKFVSTA-------- 322 Query: 349 TTLQSTDNQVLSNSTNTGNQFGAVVGIRHKF 379 VG+RHKF Sbjct: 323 ----------------------GGVGLRHKF 331
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 91.4 bits (227), Expect = 2e-23 Identities = 35/123 (28%), Positives = 65/123 (52%), Gaps = 1/123 (0%) Query: 2 RILLVEDEGELAAWLARALAQSGFVVERAADGLAAEAFLASGEFDAVVLDLRLPRKDGFA 61 IL+ +D+ + L +AL+++G+ V ++ ++A+G+ D VV D+ +P ++ F Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VLADMRARDDRTPVLILTAQGALDERVRGLNAGADDFLTKPFALTE-LEARLMALIRRSR 120 +L ++ PVL+++AQ ++ GA D+L KPF LTE + AL R Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 121 GRA 123 + Sbjct: 125 RPS 127
>PF06580#Sensor histidine kinase Length = 349 Score = 36.4 bits (84), Expect = 2e-04 Identities = 20/109 (18%), Positives = 37/109 (33%), Gaps = 36/109 (33%) Query: 372 LVHNAIRY----TPPGGRITVRAIKDSDAALVCVDDTGPGMNAVERAHAFERFRRAHEGG 427 LV N I++ P GG+I ++ KD+ + V++TG Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLA------------------- 303 Query: 428 TLPGGPKDARYAAEGSGLGLA-----IARAYAARSGGRIELADGEPNSR 471 + E +G GL + Y + ++ G+ N+ Sbjct: 304 --------LKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAM 344
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.018 Identities = 13/34 (38%), Positives = 17/34 (50%) Query: 31 VVSLLGPSGSGKTTLLRAVAGLEQASSGTVKIGE 64 V L G G GK+TL+ + GL+ S IG Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGT 631
>TATBPROTEIN#Bacterial sec-independent translocation TatB protein signature. Length = 171 Score = 77.4 bits (190), Expect = 1e-20 Identities = 30/110 (27%), Positives = 55/110 (50%), Gaps = 4/110 (3%) Query: 1 MIDLGISKLALIGAVALVVIGPERLPKVARTAGALIGRAQRYIADVKAEVSREIELEELR 60 M D+G S+L L+ + LVV+GP+RLP +T I + V+ E+++E++L+E + Sbjct: 1 MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNELTQELKLQEFQ 60 Query: 61 KMRTEFE-EAARNVEQTIHQEVS--RHTSEINERLNEAL-GDPASRQTAT 106 + E + N+ + + R +E +R A + AS + T Sbjct: 61 DSLKKVEKASLTNLTPELKASMDELRQAAESMKRSYVANDPEKASDEAHT 110
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 34.8 bits (80), Expect = 6e-04 Identities = 43/191 (22%), Positives = 74/191 (38%), Gaps = 21/191 (10%) Query: 64 LMRPLGALILGAYIDRHGRRAGLILTLGLMACGTLLIALVPGYATIGLAAPLLVLIGRLL 123 LM+ A +LGA DR GRR L+++L A ++A P ++ IGR++ Sbjct: 54 LMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLW--------VLYIGRIV 105 Query: 124 QGFSAGVELGGVSVYLAEISTPGRKGFFVSWQSASQQVAVMFAALLGVLLSFQLSPKEMG 183 G + G Y+A+I+ + + SA ++ +LG L MG Sbjct: 106 AGIT-GATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGL---------MG 155 Query: 184 EWGWRVPFLVGCLIVPFLFLIRRSLQETEEFKQRKHRPALGEIFRSMGENWRLVGAGTLL 243 + PF + FL E + + RP E + ++R T++ Sbjct: 156 GFSPHAPFFAAAALNGLNFLT--GCFLLPESHKGERRPLRREAL-NPLASFRWARGMTVV 212 Query: 244 VVMTTVSFYLI 254 + V F + Sbjct: 213 AALMAVFFIMQ 223
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 32.5 bits (74), Expect = 0.003 Identities = 43/192 (22%), Positives = 76/192 (39%), Gaps = 23/192 (11%) Query: 64 LMRPLGAIVLGAYIDRHGRRAGLILTLVLMACGTMLIALVPGYGTIGLAAPLLVLIGRLL 123 LM+ A VLGA DR GRR L+++L A ++A P ++ IGR++ Sbjct: 54 LMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAP--------FLWVLYIGRIV 105 Query: 124 QGFSAGGEPGGVSVYLSEIATPGRKGFYVSWQSGSQQVAVMFAALLGVLLSFKLSPKEMG 183 G + G Y+++I + + + S ++ +LG L MG Sbjct: 106 AGIT-GATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGL---------MG 155 Query: 184 EWGWRVPFLIGCLIVPFLFFIRR-SLRETEEFEQRKHRPTMGELLRSMGENWRLAGAGTL 242 + PF + F L E+ + E+R + + ++R A T+ Sbjct: 156 GFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERR----PLRREALNPLASFRWARGMTV 211 Query: 243 LAVMTTVSFYLI 254 +A + V F + Sbjct: 212 VAALMAVFFIMQ 223
>PF06580#Sensor histidine kinase Length = 349 Score = 31.8 bits (72), Expect = 0.005 Identities = 19/108 (17%), Positives = 38/108 (35%), Gaps = 31/108 (28%) Query: 330 LIRNAMRYA--------RQAITVRAEAGTYGSLCLTVEDDGPGIPAAERARVFEPFYRLD 381 L+ N +++ + + + GT + L VE+ G + Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGT---VTLEVENTGSLALKNTK----------- 308 Query: 382 ASRDRHTGGFGLGLAIVR-RIALVHGGEVRLDTGGS-GGARFVLLLPA 427 G GL VR R+ +++G E ++ G ++L+P Sbjct: 309 -------ESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIPG 349
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 76.4 bits (188), Expect = 3e-18 Identities = 25/151 (16%), Positives = 58/151 (38%), Gaps = 5/151 (3%) Query: 7 KTRVLLIEDDDRLAQLVSEYLGNYEFTVEVVRRGDIAVAAVREHRPALVILDLMLPHMDG 66 +L+ +DD + ++++ L + V + + LV+ D+++P + Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 67 MEVCRRIRA-FSRVPVLILTARVDTYDQVAGLEIGADDYVLKPVEPRLLVARARALLRRV 125 ++ RI+ +PVL+++A+ + E GA DY+ KP + ++ R Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLT----ELIGIIGRA 118 Query: 126 ASAMPAAEPATPRDDTLVFGELAISPPNRTV 156 + D + S + + Sbjct: 119 LAEPKRRPSKLEDDSQDGMPLVGRSAAMQEI 149
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 59.1 bits (143), Expect = 2e-11 Identities = 19/65 (29%), Positives = 28/65 (43%), Gaps = 7/65 (10%) Query: 585 FYGTSAAAPHVAGVAALMRQAVPKA-----TPEQIYSALRKTAVDMDAPGHDNATGAGFV 639 F GTS A PHVAG AL++Q + T ++Y+ L K + + G G + Sbjct: 240 FSGTSMATPHVAGALALIKQLANASFERDLTEPELYAQLIKRTIPLG--NSPKMEGNGLL 297 Query: 640 QPERA 644 Sbjct: 298 YLTAV 302 Score = 34.4 bits (79), Expect = 0.001 Identities = 27/196 (13%), Positives = 49/196 (25%), Gaps = 43/196 (21%) Query: 157 VKGLGIELTGKGITVGLISDSFN-----CNSQLNQDARYVA-QNGRQDTMEDDIARGELP 210 + + G+G+ V ++ + +++ + G + +D G Sbjct: 31 APAVWNQTRGRGVKVAVLDTGCDADHPDLKARIIGGRNFTDDDEGDPEIFKDYNGHGTH- 89 Query: 211 GNGRIRIVKELRDCTDGTDEGRAMAEIIHDVAPGADIVFY-----SGGAGMADFAQGIET 265 GT + VAP AD++ G QGI Sbjct: 90 --------------VAGTIAATENENGVVGVAPEADLLIIKVLNKQGSGQYDWIIQGIY- 134 Query: 266 LALPKNKSNAQGVAGGGAQVIVDDLQYSYEPAFQSGIVGAAIDNVVKNHGIAYFTAGGND 325 +I S + A+ V I A GN+ Sbjct: 135 -----------YAIEQKVDII----SMSLGGPEDVPELHEAVKKAV-ASQILVMCAAGNE 178 Query: 326 GVGASPVSYINNNARF 341 G G + + Sbjct: 179 GDGDDRTDELGYPGCY 194
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 393 bits (1011), Expect = e-128 Identities = 205/706 (29%), Positives = 314/706 (44%), Gaps = 94/706 (13%) Query: 46 PAASNPGDEVSLNFVNADLETVVKAVGQATGKNFIVDPRVKGTVNLVTEKPVTRAQALES 105 PAA+ E S +F D++ + V + K I+DP V+GT+ + + + Q + Sbjct: 24 PAAAE---EFSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRSYDMLNEEQYYQF 80 Query: 106 LGSILRMQGYAIVE-GNGFTKVVPEADAKLQGSPTSVGPGGARGGEQVVTQVFRLQYESA 164 S+L + G+A++ NG KVV DAK P + G E VVT+V L +A Sbjct: 81 FLSVLDVYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIGDE-VVTRVVPLTNVAA 139 Query: 165 NNLVPVLRPMI--APNNTITAYPANNTLVITDYADNLRRIARIITSIDSPAAGETELIAL 222 +L P+LR + A ++ Y +N L++T A ++R+ I+ +D+ + L Sbjct: 140 RDLAPLLRQLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDNAGDRSVVTVPL 199 Query: 223 KNAVAIDAAATLQKLLDPSGTAGGAGAGAALADPSLRTSVVAEPRSNSVLVRASSAARMA 282 A A D + +L + + G+ A +VVA+ R+N+VLV +R Sbjct: 200 SWASAADVVKLVTELNKDTSKSALPGSMVA--------NVVADERTNAVLVSGEPNSR-Q 250 Query: 283 QAKQLLAKLDVPGTRPGNIWVVPLKNANAVQLATTLRAIVAADATLSASQSGGPGGQSAA 342 + ++ +LD GN V+ LK A A L L I Sbjct: 251 RIIAMIKQLDRQQATQGNTKVIYLKYAKASDLVEVLTGI--------------------- 289 Query: 343 QGAQAQQPATTGTQTSQNTQTGSYSSSSGSSSGMGSGNSSFRASFGQSNLPTTGGIIQAD 402 SS+ S ++ + II+A Sbjct: 290 ------------------------SSTMQSEKQAAKPVAALDKNI----------IIKAH 315 Query: 403 PATNALIITASEPVYRNLRTVIDDLDARRAQVYIESMIVEVTSDKASQLGIQWMVGAGGP 462 TNALI+TA+ V +L VI LD RR QV +E++I EV LGIQW Sbjct: 316 GQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLGIQW----ANK 371 Query: 463 NTYGFGGTNFGSGVGNILNLGVIAATVGSGGIGSTAAQTALGSITGSNVSGLNGGNFGVF 522 N TN G + + G + S S +S NG G + Sbjct: 372 NAGMTQFTNSGLPISTAI-----------AGANQYNKDGTVSSSLASALSSFNGIAAGFY 420 Query: 523 NKNTGLGAILSALGSDGSVNVLSTPNLITLDNEEAKILIGQNVPITTGSYAQTGSSASVT 582 N +L+AL S ++L+TP+++TLDN EA +GQ VP+ TGS +G + Sbjct: 421 QGN--WAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVPVLTGSQTTSGDN---- 474 Query: 583 PFQTFDRKDVGITLRVKPQITDGGMVKMQIFQESSAVVNGTQNATQ--GPTTNVRSIETN 640 F T +RK VGI L+VKPQI +G V ++I QE S+V + + + G T N R++ Sbjct: 475 IFNTVERKTVGIKLKVKPQINEGDSVLLEIEQEVSSVADAASSTSSDLGATFNTRTVNNA 534 Query: 641 VIANDGQVIVLGGLLEDNYQDSEQKVPGLGDIPVLGALFRSESKTRKKTNLLVFLRPYIL 700 V+ G+ +V+GGLL+ + D+ KVP LGDIPV+GALFRS SK K NL++F+RP ++ Sbjct: 535 VLVGSGETVVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRNLMLFIRPTVI 594 Query: 701 RTAEATGALSDNRYNYMRDAQQGFVSPNVLPTTSDRDTPVLPSPES 746 R + S +Y DAQ ++D + + Sbjct: 595 RDRDEYRQASSGQYTAFNDAQSKQRGKENNDAMLNQDLLEIYPRQD 640
>PF06580#Sensor histidine kinase Length = 349 Score = 33.3 bits (76), Expect = 0.003 Identities = 11/71 (15%), Positives = 28/71 (39%), Gaps = 5/71 (7%) Query: 571 EIRVGTAVESTGVLVSIVDNGRGFDVEKTLAAGKGNGLRNLQRRAQAI---DGTVRWTSG 627 +I + ++ V + + + G K G GL+N++ R Q + + ++ + Sbjct: 280 KILLKGTKDNGTVTLEVENTGSLA--LKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEK 337 Query: 628 PEGTQFTLWLP 638 + +P Sbjct: 338 QGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 59.5 bits (144), Expect = 2e-12 Identities = 21/118 (17%), Positives = 49/118 (41%), Gaps = 2/118 (1%) Query: 10 LPSIRVAIVEDDSGFLDALTQALACAPDMHLTGVAGSRAEGLLLLDGAPADVLLVDLGLP 69 + + + +DD+ L QAL+ A + + + A + D+++ D+ +P Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAG--YDVRITSNAATLWRWIAAGDGDLVVTDVVMP 58 Query: 70 DGSGIDVIEAAARKWSACSIMVSTNFGDEIHVMRSIEVGAAGYLLKDSSAARILDEIR 127 D + D++ + ++V + + +++ E GA YL K ++ I Sbjct: 59 DENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 35.8 bits (82), Expect = 0.001 Identities = 34/141 (24%), Positives = 59/141 (41%), Gaps = 20/141 (14%) Query: 751 DQIDGYSANYGGLLIGADREINDRWRAGGVFSYSNTAIDNTGDTSGNS---ARVNGYGLI 807 Q +S+ +G D+ I++ + GGVF+Y N D + + A+VN Y Sbjct: 1310 SQYRRFSSKSTQTQLGWDQTISNNVQLGGVFTYVRN--SNNFDKATSKNTLAQVNFYS-- 1365 Query: 808 GYASYTGNPWYVNLS-GAAVQQRYDTSRLVSMQGLSGTASGHFSGQQYVARTEAGYPLSV 866 Y N WY+ + G Q S+L + + F+ AG ++ Sbjct: 1366 --KYYADNHWYLGIDLGYGKFQ----SKLQTNH------NAKFARHTAQFGLTAGKAFNL 1413 Query: 867 GSVTLTPLASLTYSYLTQDSY 887 G+ +TP+ + YSYL+ + Sbjct: 1414 GNFGITPIVGVRYSYLSNADF 1434
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 42.2 bits (99), Expect = 1e-06 Identities = 19/93 (20%), Positives = 33/93 (35%) Query: 86 NLAEMYRQKGLLAEAEDAARRAVAMDPALVSGWNNLGIVLQEAGKFAESLDCLERVILLQ 145 +LA Q G +A + +D + LG Q G++ ++ ++ Sbjct: 41 SLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMD 100 Query: 146 PDGAQAHNNLANTLRRLERLERAESHYRQALEL 178 + + A L + L AES A EL Sbjct: 101 IKEPRFPFHAAECLLQKGELAEAESGLFLAQEL 133 Score = 29.1 bits (65), Expect = 0.040 Identities = 22/124 (17%), Positives = 42/124 (33%), Gaps = 1/124 (0%) Query: 211 ELSPRLVDAYLNLAEAEMGRHRHEAALRVLDTLSTFAPQHPAALTARANVLKRVERLDEA 270 E+S ++ +LA + ++E A +V L + + + D A Sbjct: 30 EISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLA 89 Query: 271 LAVARQAVVLAPRSAEAHHALAMALQTLGQTDEALPHFEQAARLPGAVAE-EALVGRATL 329 + ++ + A L G+ EA A L E + L R + Sbjct: 90 IHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQELIADKTEFKELSTRVSS 149 Query: 330 LMEA 333 ++EA Sbjct: 150 MLEA 153
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 27.9 bits (62), Expect = 0.033 Identities = 15/54 (27%), Positives = 25/54 (46%), Gaps = 3/54 (5%) Query: 21 AALVIFVGLSLVTGVLYPVVVTGIGKAAFPAQAGGSI---IERGGKPVGSALIG 71 +++ FVG S + ++ + G G AAFPA + I + + LIG Sbjct: 92 GSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIG 145
>LIPPROTEIN48#Mycoplasma P48 major surface lipoprotein signature. Length = 428 Score = 28.8 bits (64), Expect = 0.023 Identities = 16/58 (27%), Positives = 29/58 (50%), Gaps = 4/58 (6%) Query: 41 QIWEVVQKVAKKDGLDIKIIEFNDYAQP--NPALDAGD--LDANGFQHQPFLDGQVKA 94 +E ++ + K+ G++I +E + + N AL AG NGF+HQ + + A Sbjct: 81 SAFEALKAINKQTGIEINNVEPSSNFESAYNSALSAGHKIWVLNGFKHQQSIKQYIDA 138
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 53.3 bits (128), Expect = 8e-10 Identities = 17/73 (23%), Positives = 27/73 (36%), Gaps = 1/73 (1%) Query: 9 VLVVDGQLGQRTAARQVLQTLGVQQILAAGDGREALDLLHLCQFDLVLCDIAMPGMDGSA 68 +LV D RT Q L G + + + DLV+ D+ MP + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYD-VRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 69 LMQRMRLHDGRPP 81 L+ R++ P Sbjct: 65 LLPRIKKARPDLP 77
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 41.4 bits (97), Expect = 1e-06 Identities = 21/83 (25%), Positives = 36/83 (43%), Gaps = 5/83 (6%) Query: 6 SIVAADDHPVILMGLATAIQQFPRQKIIAQAHDGHALLALLESTDCDVVVTDYHMNGDAA 65 +I+ ADD I L A+ + + + L + + D D+VVTD M + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYD--VRITSNAATLWRWIAAGDGDLVVTDVVMPDE-- 60 Query: 66 SDGMQLLTRLRARHPQRAVVVCT 88 + LL R++ P V+V + Sbjct: 61 -NAFDLLPRIKKARPDLPVLVMS 82
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 55.6 bits (134), Expect = 8e-11 Identities = 71/362 (19%), Positives = 122/362 (33%), Gaps = 56/362 (15%) Query: 25 AQTSAVTLYGLIDTTISTVSNTNAAGARTTGFQVP---WFSGSRWGLTGKEDLGGGTSAI 81 A + VTLYG I + T + GA+ + GS+ G G+EDLG G AI Sbjct: 16 AAMADVTLYGTIKAGVETSRSVAHNGAQAASVETGTGIVDLGSKIGFKGQEDLGNGLKAI 75 Query: 82 FKLESEFETPTGNMDTPGVLFNRDAWVGLSNPLFGKLTFGRQNALARDVSGIYGDPYTSA 141 +++E + T NR +++GL FGKL GR N++ +D I +P+ S Sbjct: 76 WQVEQK----ASIAGTDSGWGNRQSFIGLKGG-FGKLRVGRLNSVLKDTGDI--NPWDSK 128 Query: 142 EVTLDEGGYTNVNNFKQLIFYAGSATGTRLNNGVVWKKLWDGGFFTGLAYQFGEVPGQFS 201 L + Y G + Y + G Sbjct: 129 SDYLGVNKIAEPEARLISVRYDSPEF---------------AGLSGSVQYALNDNAG-RH 172 Query: 202 QNTTESAALGYNGGNFHLAAFAQQAKVNGFTDRSYSLGGNV--ILGMFRVNAGYYHYTGE 259 + + A Y G F + + + + + ++ + +A Y + Sbjct: 173 NSESYHAGFNYKNGGFFVQYGGAYKRHHQVQENVNIEKYQIHRLVSGYDNDALYASVAVQ 232 Query: 260 QPAAIGNRKDDAYTVSLKIAPPGAFDYE-----IGYQIMKAGNAAFNADGNTLNAYADVS 314 Q A ++ ++ ++A A+ + + Y G+ + N V Sbjct: 233 QQDAKLVEENYSHNSQTEVAATLAYRFGNVTPRVSYAHGFKGSFD-ATNYNNDYDQVVVG 291 Query: 315 TATASGSGRKNTLYGSVFYHVSKRTEFYVAADYMKLKDQYIVGSTNGHNSQTEFGVGMRT 374 Y SKRT V+A +++ G T GVG+R Sbjct: 292 AE----------------YDFSKRTSALVSAGWLQE------GKGESKFVSTAGGVGLRH 329 Query: 375 RF 376 +F Sbjct: 330 KF 331
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 92.2 bits (229), Expect = 8e-24 Identities = 32/112 (28%), Positives = 59/112 (52%) Query: 2 KLLLIEDNAPLAQWLSEALRRAQFTVDHASDGESADTLLLTQHYDVVLLDLQLPSLSGRA 61 +L+ +D+A + L++AL RA + V S+ + + D+V+ D+ +P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VLQRLRDRRNAVPVMILTAAGGIDDKVACLGAGADDYLVKPFEIRELIARIQ 113 +L R++ R +PV++++A + GA DYL KPF++ ELI I Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>PF09025#YopR Core Length = 143 Score = 33.8 bits (77), Expect = 5e-04 Identities = 20/74 (27%), Positives = 34/74 (45%) Query: 76 WSVFRTLSPQAMFDVVSTRGIPFLQALGDNDPAAGRHMEDIRFTLTTPALLARIVQLLDA 135 ++V+ + SP+A + + F QALG PAAGR + + LL R Q L Sbjct: 10 FAVYPSASPKAANLPAVDQVLAFEQALGGEPPAAGRRLAGLENGALGERLLQRFAQPLQG 69 Query: 136 IPLHRRDVRGAVYE 149 + R +++ + Sbjct: 70 LEADRLELKAMLRA 83