>SECBCHAPRONE#Bacterial protein-transport SecB chaperone protein signature. Length = 170 Score = 207 bits (528), Expect = 1e-71 Identities = 80/161 (49%), Positives = 113/161 (70%), Gaps = 4/161 (2%) Query: 4 VANNEQ--QGPQFNIQRVYTKDISFETPNSPAVFQKEWNPEVKLDLDTRSNKLSDDVYEV 61 A + Q Q P IQR+Y KD+SFE PN P +FQ++W P++ DL T + ++ DD+YEV Sbjct: 8 NAADTQATQQPVLQIQRIYVKDVSFEAPNLPHIFQQDWEPKLSFDLSTEAKQVGDDLYEV 67 Query: 62 VLSLTVTA--KNGEETAFLCEVQQAGIFAIAGLTEQQLAHSLGAYCPNVLFPYAREAIGS 119 L+++V ++ + AF+CEV+QAG+F I+GL E Q+AH L + CPN+LFPYARE + S Sbjct: 68 CLNISVETTMESSGDVAFICEVKQAGVFTISGLEEMQMAHCLTSQCPNMLFPYARELVSS 127 Query: 120 LVSRGTFPQLNLAPVNFDALFAQYVQQRQAAAADAPAEEAN 160 LV+RGTFP LNL+PVNFDALF Y+Q+++ A E + Sbjct: 128 LVNRGTFPALNLSPVNFDALFMDYLQRQEQAEQTTEEENKD 168
>DNABINDNGFIS#DNA-binding protein FIS signature. Length = 98 Score = 34.6 bits (79), Expect = 1e-04 Identities = 27/104 (25%), Positives = 46/104 (44%), Gaps = 18/104 (17%) Query: 249 NPGEAISINLLPGEDVRAKIQQALEASPKQSLRNALSQWLPKRLVEVLFDESLLNKALNQ 308 + ++++ + +D Q+ L S KQ+L+N +Q + + + L + Sbjct: 6 VNSDVLTVSTVNSQD--QVTQKPLRDSVKQALKNYFAQLNGQDVND-----------LYE 52 Query: 309 LVHAEREQLALDLESWTLVMNGTEGYRTAEVTLGGIDTDELSSK 352 LV AE EQ LD +VM T G +T + GI+ L K Sbjct: 53 LVLAEVEQPLLD-----MVMQYTRGNQTRAALMMGINRGTLRKK 91
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 44.0 bits (104), Expect = 5e-07 Identities = 21/152 (13%), Positives = 48/152 (31%), Gaps = 17/152 (11%) Query: 45 VVVALPVAQGSIVTKGTVLVQLDDTQQKSHVAKALADVAQATANYEKLLKGAREEEIAAA 104 +V + V +G V KG VL++L ++ K + + QA + Sbjct: 106 IVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLE---------QTRYQIL 156 Query: 105 RAAVAGTRARLQESEANYRRIASMAKDNLASKADLDRALASRDADAANLESAQENLLELV 164 ++ + + ++ L + + ++ E + Sbjct: 157 SRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLD------ 210 Query: 165 SGSREEDIRFALANLQASEAVLLGEQKKLDDL 196 + + LA + E + E+ +LDD Sbjct: 211 --KKRAERLTVLARINRYENLSRVEKSRLDDF 240
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 29.3 bits (65), Expect = 0.025 Identities = 14/34 (41%), Positives = 20/34 (58%) Query: 112 EQTARIQELLNTYGLEQKADQLAGSMSGGQKQRL 145 E+ + LL YG+E+K D G++S QKQ L Sbjct: 524 EKQKGVTNLLIKYGIERKPDSTKGTLSNWQKQML 557
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 44.9 bits (106), Expect = 2e-07 Identities = 44/161 (27%), Positives = 75/161 (46%), Gaps = 13/161 (8%) Query: 194 GVILTMTMIMFT----SAAIVRERERGNLEMLITTPIRPIELMLGKII----PYMFIGIV 245 G++ T M T AA R + E ++ T +R +++LG++ G Sbjct: 72 GMVATSAMTAATFETIYAAFGRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAG 131 Query: 246 QVIIILGLGYSVFDVPINGSLLQLAGATLLFIMASLTLGLVISTIAKSQLQSMQMTIFVL 305 ++ LGY+ + SLL L +A +LG+V++ +A S + V+ Sbjct: 132 IGVVAAALGYTQWL-----SLLYALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVI 186 Query: 306 LPSILLSGFMFPYEGMPIEAQYIAEALPATHFMRLIRGVVL 346 P + LSG +FP + +PI Q A LP +H + LIR ++L Sbjct: 187 TPILFLSGAVFPVDQLPIVFQTAARFLPLSHSIDLIRPIML 227
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 25.7 bits (56), Expect = 0.028 Identities = 14/73 (19%), Positives = 27/73 (36%), Gaps = 10/73 (13%) Query: 9 DESRFVINVDGAQAVLAYELYEDQTAADSPGRRCNFN------NTYVPPELRGRGLAEKL 62 + +V A A+ Y + R N+N + V + R +G+ L Sbjct: 55 MDVSYVEEEGKA----AFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTAL 110 Query: 63 VRRGLKWAKAEGL 75 + + ++WAK Sbjct: 111 LHKAIEWAKENHF 123
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 37.4 bits (87), Expect = 1e-04 Identities = 14/33 (42%), Positives = 19/33 (57%) Query: 348 LAGMTRNAAKALGIDDHVGVIEVGMTADFCIWN 380 +A T N A A G+ +G +EVG AD +WN Sbjct: 406 IAKYTINPAIAHGLSHEIGSLEVGKRADLVLWN 438 Score = 34.3 bits (79), Expect = 8e-04 Identities = 19/61 (31%), Positives = 32/61 (52%), Gaps = 6/61 (9%) Query: 23 YGAITDAALAVQDGKIAWVGKRSD---LPEFDVF---GTPIYKGKGGWITPGLIDAHTHL 76 + I A + ++DG+IA +GK + P + GT + G+G +T G +D+H H Sbjct: 80 HWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIVTAGGMDSHIHF 139 Query: 77 I 77 I Sbjct: 140 I 140
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 28.8 bits (64), Expect = 0.005 Identities = 21/127 (16%), Positives = 42/127 (33%), Gaps = 8/127 (6%) Query: 14 TETIELYQANEWSSADKPDLLILALRNS-HTLVTARYEGKLVGIGNAISDGHLVVYYSHM 72 T T E + + + D+ + + E +G S+ + + Sbjct: 36 TYTEERFSKPYFKQYEDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRSNWNGYALIEDI 95 Query: 73 LVHPSLHGKGIGRKMMA-----AMQSVYCGFHQQMLTADGDAVEFYKALGFERAGKTEPM 127 V KG+G ++ A ++ +CG + + A FY F G + M Sbjct: 96 AVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF-IIGAVDTM 154 Query: 128 WIYAGTE 134 +Y+ Sbjct: 155 -LYSNFP 160
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 70.2 bits (172), Expect = 2e-16 Identities = 32/122 (26%), Positives = 52/122 (42%), Gaps = 2/122 (1%) Query: 1 MPIAKILLVDDHPALRQGLAQLMSLEESLDVVAQASSGEEAISLAVQYEPDIILLDLNMR 60 M A IL+ DD A+R L Q +S DV S+ + D+++ D+ M Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAG-YDVRI-TSNAATLWRWIAAGDGDLVVTDVVMP 58 Query: 61 GLSGIDTLISLKNAQVKSKVIIFTVSDNESDVVQAIKFNTDGYLLKDSEPEELIEKIHLA 120 + D L +K A+ V++ + + ++A + YL K + ELI I A Sbjct: 59 DENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 121 LQ 122 L Sbjct: 119 LA 120
>PF06580#Sensor histidine kinase Length = 349 Score = 31.4 bits (71), Expect = 0.008 Identities = 16/94 (17%), Positives = 32/94 (34%), Gaps = 8/94 (8%) Query: 481 IRFSYDLPQHCLSANQEIHLLQIIREGLSNIHRHA---KASEAGVRLS--PKGELIKLDI 535 ++F + + L+Q + E N +H + L + L++ Sbjct: 240 LQFENQINPAIMDVQVPPMLVQTLVE---NGIKHGIAQLPQGGKILLKGTKDNGTVTLEV 296 Query: 536 WDNGAGLPGTLQTQGHFGLGIMRERVSSLKGQMY 569 + G+ + GL +RER+ L G Sbjct: 297 ENTGSLALKNTKESTGTGLQNVRERLQMLYGTEA 330
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 50.4 bits (120), Expect = 8e-10 Identities = 17/58 (29%), Positives = 31/58 (53%) Query: 3 SKTLEHILNVSEQLIYKDGVIGFKFCTVAKEAGISTTSLYKFFGNKEDILVALASKSF 60 +T +HIL+V+ +L + GV +AK AG++ ++Y F +K D+ + S Sbjct: 10 QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSE 67
>THERMOLYSIN#Thermolysin metalloprotease (M4) family signature. Length = 544 Score = 28.8 bits (64), Expect = 0.026 Identities = 17/53 (32%), Positives = 28/53 (52%), Gaps = 4/53 (7%) Query: 219 GLTLNSGIYGNTFFLLT---GFHGMHVT-LGTVFLIVLFFRVLKGHFTPDKHF 267 G+ NSGI +LL+ +G+ VT +G + +F+R L + TP +F Sbjct: 457 GVHTNSGIINKAAYLLSQGGVHYGVSVTGIGRDKMGKIFYRALVYYLTPTSNF 509
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 55.1 bits (132), Expect = 7e-10 Identities = 40/241 (16%), Positives = 79/241 (32%), Gaps = 13/241 (5%) Query: 12 KDKSNEEAQA-----VEAAKLEAEKLELEEAEKLELERAEAERLAAEQAETERLAEEARL 66 SN E A A E E ++ EQ TE A+ + Sbjct: 1009 SVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREV 1068 Query: 67 AVEQAEAERIESERVEAERHAAEQAEAQRVA---EETAAEQARLAAELAAQAETQRIEAE 123 A E + ++ E + +E E Q T ++ + E E ++ ++ Sbjct: 1069 AKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQ 1128 Query: 124 RLESEREAAEQAEGQRIEAARLESERVIAEQAEAQ---RVATEQASQAEAARIEAERIEA 180 S ++ + + E AR V ++ ++Q TEQ ++ ++ +E E+ Sbjct: 1129 --VSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTES 1186 Query: 181 ARIESERVVAEQAESARIAAEQAEAQRIEATRIEAARIEAERIEAARIEAARIEAARIEA 240 + + V E E+ A Q + + + + R +E A + Sbjct: 1187 TTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRST 1246 Query: 241 E 241 Sbjct: 1247 V 1247 Score = 49.3 bits (117), Expect = 4e-08 Identities = 27/184 (14%), Positives = 59/184 (32%), Gaps = 17/184 (9%) Query: 102 AEQARLAAELAAQAETQRIEAERLESEREAAEQAEGQRIEAARLESERVIAEQAEAQRVA 161 E+ + I+A+ E A + +E E VA Sbjct: 985 VEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPP-APATPSETTET--VA 1041 Query: 162 TEQASQAEAARIEAERIEAARIESERVVAEQAESARIAAEQAEAQRIEATRIEAARIEAE 221 +++ + ++ V E + + + E + + E E + Sbjct: 1042 ENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETK 1101 Query: 222 RIEAARIEAARIEAARIEAERIEAERIEAERIEAERIEAEAADQAAQLEAAEEQ-QPEPQ 280 E A +E E A++E E+ + E ++ ++ + + Q E + Q +P + Sbjct: 1102 --ETATVEKE--EKAKVETEKTQ---------EVPKVTSQVSPKQEQSETVQPQAEPARE 1148 Query: 281 AKPV 284 P Sbjct: 1149 NDPT 1152
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 117 bits (295), Expect = 3e-31 Identities = 68/357 (19%), Positives = 109/357 (30%), Gaps = 89/357 (24%) Query: 31 SDPLYKHQWHLKNTGQAAFSENGGKAGNDLKTKQAHKKGALGQGVQISVVDTGLQIDHID 90 Q N G + + G+GV+++V+DTG DH D Sbjct: 8 IPYQVIKQEQQVNEIPR-----GVEMIQ---APAVWNQTR-GRGVKVAVLDTGCDADHPD 58 Query: 91 LADNVVPG-SMDLITGSDY--PEDTHGHGTAVGGIIAAVGFNGEGVRGIAPKAGINGFNF 147 L ++ G + D +D +GHGT V G IAA N GV G+AP+A + Sbjct: 59 LKARIIGGRNFTDDDEGDPEIFKDYNGHGTHVAGTIAATE-NENGVVGVAPEADLLIIKV 117 Query: 148 LFEQ--SMNSWLLSHGYGEGTENTELFNQSYGSQALFIPQFDLENDPQLAIENAVMEDVA 205 L +Q W++ Y + ++ + S G + + A++ AV Sbjct: 118 LNKQGSGQYDWIIQGIYYAIEQKVDIISMSLGG-------PEDVPELHEAVKKAVA---- 166 Query: 206 SNSNNGRGAAFVSSAGNSYNYYGYAGYYFLPADYFDVEASNHGLPMQNSNMTNSKATHWS 265 + +AGN + P Y Sbjct: 167 ------SQILVMCAAGNEGDGDDRTDELGYPGCYN-----------------------EV 197 Query: 266 TTVSAINANGERSSYSTVGANVFMAATGGEYGSETPAMVTTDLMGCDSGFNDSTGLGKNG 325 +V AIN + S +S V + A G +++T G Sbjct: 198 ISVGAINFDRHASEFSNSNNEVDLVAPGE-------DILSTVPGGK-------------- 236 Query: 326 LHGGTADDPNCNYTSVMNGTSSAAPSMVGAIAAVMSANPQLTTRDAKHVLALTAKKT 382 + +GTS A P + GA+A + RD Sbjct: 237 -------------YATFSGTSMATPHVAGALALIKQLANASFERDLTEPELYAQLIK 280
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 107 bits (269), Expect = 2e-30 Identities = 71/257 (27%), Positives = 118/257 (45%), Gaps = 29/257 (11%) Query: 3 KRVLITGSSRGIGKAIALKLAASGHDIAMHFHSNQTAADATKAELEQLEIKVSCLQF--- 59 K ITG+++GIG+A+A LA+ G I A D +LE++ + Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHI--------AAVDYNPEKLEKVVSSLKAEARHAE 60 Query: 60 ----DIADRAAVKQAIEQDIEQHGAYYGVVLNAGINADTAFPAMTESEWDSVVHTNLDGF 115 D+ D AA+ + + + G +V AG+ ++++ EW++ N G Sbjct: 61 AFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGV 120 Query: 116 YNVIHPTVMPMVQGRQGGRIITLASVSGIAGNRGQVNYSASKAGIIGATKALSLELAKRK 175 +N +V + R+ G I+T+ S Y++SKA + TK L LELA+ Sbjct: 121 FNASR-SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYN 179 Query: 176 ITVNCIAPGLIETDM-----VSDIPKEMV--------NNLVPMRRMGKPSEIAGLANYLM 222 I N ++PG ETDM + E V +P++++ KPS+IA +L+ Sbjct: 180 IRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLV 239 Query: 223 SDDAAYITRQVISVNGG 239 S A +IT + V+GG Sbjct: 240 SGQAGHITMHNLCVDGG 256
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 45.6 bits (108), Expect = 9e-07 Identities = 29/145 (20%), Positives = 57/145 (39%), Gaps = 25/145 (17%) Query: 675 LLALALLIAGIIFTFRFGVRLAAVV-VAVPA--LSALLTLACLGVSNNPLTLFHALALIL 731 L +L+ +++ F +R + +AVP L LA G S N LT+F ++L Sbjct: 344 LFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMF---GMVL 400 Query: 732 VFGIGIDYSL----------------FFAESKQQTRGVMMAVFMSAMSTLLAFGLLAF-- 773 G+ +D ++ +++ + A+ AM F +AF Sbjct: 401 AIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFG 460 Query: 774 -SQTPAINAFGLTLLLGIGFTFLLS 797 S F +T++ + + L++ Sbjct: 461 GSTGAIYRQFSITIVSAMALSVLVA 485 Score = 41.0 bits (96), Expect = 2e-05 Identities = 49/301 (16%), Positives = 104/301 (34%), Gaps = 32/301 (10%) Query: 203 VLLKTIAPKVLNQSPQFAAIVMAKGRDSAFNPNAQQLQLSALTAAFDAVKQQDSDI---- 258 V LK +A +V + I G+ +A +AL A A+K + +++ Sbjct: 260 VRLKDVA-RVELGGENYNVIARINGKPAAGLGIKLATGANALDTA-KAIKAKLAELQPFF 317 Query: 259 -EIIKAGALFHATAATDNAKKEVSTIGLISLLGVIALVWFAFRSFRPLTIALVTVSSSFL 317 + +K + T + EV +++ V +++ ++ R I + V L Sbjct: 318 PQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLL 377 Query: 318 FAVVTTTAVFGELHLLTLVFGTSLIGISIDY-------CFHYYCERLNHPSHSSDRVIQQ 370 A ++ LT+ IG+ +D E P ++++ + Q Sbjct: 378 GTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQ 437 Query: 371 IFIAISLALLTSVIAYS---AIGLAPFPGMQQVAIFCASGLVGAYLTLLLAYPTLAARPL 427 I A+ + + G + +Q +I S + + L L+ P L A L Sbjct: 438 IQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLL 497 Query: 428 RDG---------------NRALDYASRYQGFMLSLMPTVPRKRLLLAVGTCMFIIIGFTQ 472 + N D++ + + + + LL+ +++ F + Sbjct: 498 KPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLR 557 Query: 473 L 473 L Sbjct: 558 L 558
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 107 bits (268), Expect = 4e-27 Identities = 88/401 (21%), Positives = 168/401 (41%), Gaps = 19/401 (4%) Query: 37 AFMAILDIQITNASMKEIQGGLGATLEEGSWIATAYLVAEMIAIPLSGWLSKGLDIRRYM 96 +F ++L+ + N S+ +I +W+ TA+++ I + G LS L I+R + Sbjct: 23 SFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLL 82 Query: 97 LWNSAIFIFASLLCSIAWNLES-MIAFRAMQGFFGGALIPMAFRLILEYLPDSKRAVGMA 155 L+ I F S++ + + S +I R +QG A + ++ Y+P R Sbjct: 83 LFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFG 142 Query: 156 LFGVTATFAPSIGPTLGGWLTEQFSWHYLFYINVPPGIVVMSMLAYGLVKKPINWPELKN 215 L G +GP +GG + W YL +P ++ L+KK + + Sbjct: 143 LIGSIVAMGEGVGPAIGGMIAHYIHWSYLL--LIPMITIITVPFLMKLLKKEVRIKG--H 198 Query: 216 VDVSSIITMALGMGCLEVVLEEGNRKDWFGSDFIRNLAIVAAVNIALFVYLQLKSKAPLV 275 D+ II M++G+ + F + + + IV+ ++ +FV K P V Sbjct: 199 FDIKGIILMSVGIVFFML----------FTTSYSISFLIVSVLSFLIFVKHIRKVTDPFV 248 Query: 276 NLKLLANRDFSISTIAYFLLGLALFSSIYMVPLYLSQIQDYNSLEIGEVLMWLGFPQLLI 335 + L N F I + ++ + + MVP + + ++ EIG V+++ G ++I Sbjct: 249 DPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVII 308 Query: 336 L-PFMPMLMQRFDNRYLAAFGFFMFGVSYYMNSHMTADFAGPQLIASMVVRAIG-QPFIM 393 +L+ R Y+ G VS+ S + + ++V +G F Sbjct: 309 FGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFL--LETTSWFMTIIIVFVLGGLSFTK 366 Query: 394 VPIGMLATARLQKHENASASTVLNVVRNLGGAVGIAMVSTL 434 I + ++ L++ E + ++LN L GIA+V L Sbjct: 367 TVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGL 407
>AUTOINDCRSYN#Autoinducer synthesis protein signature. Length = 216 Score = 32.5 bits (74), Expect = 3e-04 Identities = 14/63 (22%), Positives = 25/63 (39%), Gaps = 12/63 (19%) Query: 5 SLSFSELSLNELYDLLKLRVDVFV--------VEQNCAYPELDDKDRHSQTQHLLGLNEQ 56 ++ + LS + +L LR + F E D D ++ T +L G+ + Sbjct: 6 DVNHTLLSETKSGELFTLRKETFKDRLNWAVQCTDGM---EFDQYD-NNNTTYLFGIKDN 61 Query: 57 GVI 59 VI Sbjct: 62 TVI 64
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 33.1 bits (75), Expect = 0.006 Identities = 34/289 (11%), Positives = 90/289 (31%), Gaps = 38/289 (13%) Query: 585 KQLNGLHNKVNEVGARLTQTERDKSTLEAEYKSIENRVVELEKSVWGLSHVELVSRVEAE 644 + L +++ +L + ++ S ++ + +E R +LEK++ G Sbjct: 85 DHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGA---------MNF 135 Query: 645 LKELLIKRSNLLEQKTSATTQITLFTKSFKAKDLELQSLISEVERKGSEHAYVTVQAYLN 704 K L +K + + K+ + + ++++ +E A + + Sbjct: 136 STADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAEL 195 Query: 705 ENAIVASSLQKHCEIKRKELDTEVLKYKVEVESLTSQCNALQQEMQVGGTWINFPQLKQQ 764 E +E E A + +++ + + Sbjct: 196 EK--------ALEGAMNFSTADSAKIKTLEAEKAAL--AARKADLE---------KALEG 236 Query: 765 KEALELRLAHSQSAVNAFYGSLSHIILVRSEDTLEKVKEFITGAIEERQRRSEELNILSS 824 + + A +L E ++++ + GA+ S ++ L + Sbjct: 237 AMNFSTADSAKIKTLEAEKAAL--------EARQAELEKALEGAMNFSTADSAKIKTLEA 288 Query: 825 KIKLLSELLASFKPYIRRISLQEELTDVERQLEQRSQVYETLAAEKEVV 873 + L A + + L + R L+ + + L AE + + Sbjct: 289 EKAALEAEKADLEHQSQ--VLNANRQSLRRDLDASREAKKQLEAEHQKL 335 Score = 32.3 bits (73), Expect = 0.011 Identities = 52/343 (15%), Positives = 98/343 (28%), Gaps = 48/343 (13%) Query: 336 AESTDTFLQIESRLLELSTQKKALTEERSKTSTQLEALNQTLSELNTELKAVDNRTLLLR 395 TDT +++ R + + L + S S +AL EL EL + Sbjct: 46 RSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKND 105 Query: 396 TSIDNASPVYTEISNRRAHFAALGLQIAEKEIAIQKEKVQFNVLNRELSEISTLKITPDL 455 S+ + E+ R+A L + + + L E + ++ K + Sbjct: 106 KSLSEKASKIQELEARKAD---LEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEK 162 Query: 456 LLTGKVDALLFEQGKIDQLTRCYADLDLIEVNITALHTTKKALTEQMELHERLLSIGLDY 515 L G ++ + KI L A L+ + + + + L Sbjct: 163 ALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAA 222 Query: 516 LSVQPSNICPLCTSPHASVEALQDKIKNRNLLSDLSQENTKKLSLSSKRQKELRDIIQSI 575 L+ + +++ A KIK + +L + + + Sbjct: 223 LAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAK 282 Query: 576 VQQ----------------------------------AIEAQVKQLNGLHNKVNE----- 596 ++ A KQL H K+ E Sbjct: 283 IKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKIS 342 Query: 597 ------VGARLTQTERDKSTLEAEYKSIENRVVELEKSVWGLS 633 + L + K LEAE++ +E + E S L Sbjct: 343 EASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLR 385
>LIPOLPP20#LPP20 lipoprotein precursor signature. Length = 175 Score = 25.5 bits (55), Expect = 0.010 Identities = 17/54 (31%), Positives = 26/54 (48%), Gaps = 2/54 (3%) Query: 3 LSKLSGLSLVCALVFGLSACAPEVGSEAWCKQMKEKPSG--DWTANEAADYAKH 54 + K+ G+S+V A+V + AP+ G K KE G DW + AK+ Sbjct: 5 VKKILGMSVVAAMVIVGCSHAPKSGISKSNKAYKEATKGAPDWVVGDLEKVAKY 58
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 51.0 bits (122), Expect = 7e-09 Identities = 35/208 (16%), Positives = 72/208 (34%), Gaps = 24/208 (11%) Query: 142 ELTAAQLALAKIEVAQLSEQTFSLEDVATATIVVDRDRTVTIAPQVDVRVLKRNVVPGQE 201 + +L L K A+ + V++ R + + + + ++ V QE Sbjct: 201 QKYQKELNLDKKR-AERLTVLARINR-YENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQE 258 Query: 202 VNKGDILLTLGGVAVAQAQADYINAAAEWSRVKRMSTSAVSASRRLMAQVDAELKRATLE 261 + +N + S + +++ V K L+ Sbjct: 259 ----------------NKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILD 302 Query: 262 AMKMTPAQIKA----LANAPETIGSYQLIAPISGRVQQ-DIALLGQIVPAGTALMQLT-D 315 ++ T I LA E + + AP+S +VQQ + G +V LM + + Sbjct: 303 KLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPE 362 Query: 316 ESHLWVEAELTPTQAEKVSIGSKTVVKV 343 + L V A + +++G ++KV Sbjct: 363 DDTLEVTALVQNKDIGFINVGQNAIIKV 390 Score = 36.0 bits (83), Expect = 3e-04 Identities = 26/140 (18%), Positives = 50/140 (35%), Gaps = 5/140 (3%) Query: 168 VATATIVVDRDRTVTIAPQVDVRVLKRNVVPGQEVNKGDILLTLGGV----AVAQAQADY 223 A + R+ I P + V + V G+ V KGD+LL L + + Q+ Sbjct: 85 TANGKLTHS-GRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSL 143 Query: 224 INAAAEWSRVKRMSTSAVSASRRLMAQVDAELKRATLEAMKMTPAQIKALANAPETIGSY 283 + A E +R + +S S + D + E + + + Y Sbjct: 144 LQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKY 203 Query: 284 QLIAPISGRVQQDIALLGQI 303 Q + + + + +L +I Sbjct: 204 QKELNLDKKRAERLTVLARI 223
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 652 bits (1684), Expect = 0.0 Identities = 222/1091 (20%), Positives = 436/1091 (39%), Gaps = 85/1091 (7%) Query: 5 LIDVAIRNRLMVVLTLVGLIIACVAMLPKLNLDAFPDVTNVQVTVNTAAEGLAAEEVEKL 64 + + IR + + + L++A + +L + +P + V+V+ G A+ V+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 65 ISYPVESAMYALPAVTEVRSLS-RTGLSIVTVVFAEGTDIYFARQQVFEQLQAAREMIPD 123 ++ +E M + + + S S G +T+ F GTD A+ QV +LQ A ++P Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 124 GVGVPEIGPNTSGLGQIYQYILRATPESGVDASELRSINDYMVKLIMMPVGGVTEVLSFG 183 V I S + + ++ VK + + GV +V FG Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPG-TTQDDISDYVASNVKDTLSRLNGVGDVQLFG 179 Query: 184 GEVRQYQVQIEPNKLLSYGLSMAQVTSALESNNRNAGGWFMDQGQE------QLVVRGYG 237 + ++ ++ + L Y L+ V + L+ N + + Sbjct: 180 AQ-YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQT 238 Query: 238 LLPAGDAGLKAIAQIPLTEVA-GTPVRVGDIAKVDYGSEIRVGAVTMTRRDEAGNAQDLG 296 + ++ L + G+ VR+ D+A+V+ G E + N + Sbjct: 239 RF----KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARI-------NGK--- 284 Query: 297 EVVAGVVLKRMGANTKETIDDISARTAMIEQALPDGVSFEVFYDQSDLVNQAVTTVRDAL 356 + GAN +T I A+ A ++ P G+ YD + V ++ V L Sbjct: 285 PAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTL 344 Query: 357 LMAFVFIVVILALFLVNIRATMLVLLSIPVSIGLALLVMSYFGMSANLMSLGGLAVAIGM 416 A + + +++ LFL N+RAT++ +++PV + +++ FG S N +++ G+ +AIG+ Sbjct: 345 FEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGL 404 Query: 417 LVDGSVVMVENIFKHLTQPDRRHLANARKRASDEDDPYHADEDGTNTTAHGESSGGITMR 476 LVD ++V+VEN+ R D+ P A E Sbjct: 405 LVDDAIVVVENV--------------ERVMMEDKLPPKEATEKSM--------------- 435 Query: 477 VMLAAKEVCSPIFFATAIIIVVFAPLFALEGVEGKLFQPMAVSIILAMISALLVALIAVP 536 ++ + ++ VF P+ G G +++ +++I+ AM ++LVALI P Sbjct: 436 -----SQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTP 490 Query: 537 ALAVYLFK----------RGVVLRESAVLKPIESVYRKLLTSTMAHPKVVGITAVVMFAM 586 AL L K G + + Y + + + ++ A Sbjct: 491 ALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLLIYALIVAG 550 Query: 587 SMMLLPRLGTEFVPELEEGTINLRVTLAPTASLATSLDVAPKLEALLLEFPEVDYALSRI 646 ++L RL + F+PE ++G + L A+ + V ++ L+ + + S Sbjct: 551 MVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNEKANVE-SVF 609 Query: 647 GAAELGGDPEPVNNIEIYIGLKPVDEWVSATNRFE--LQRKMEAKLNVYPGLLFTFSQPI 704 + N ++ LKP +E N E + R + G + F+ P Sbjct: 610 TVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGFVIPFNMP- 668 Query: 705 ATRVDELLSGVKAQLA-IKIFGPDLDVLSERGQVLTELVSQIPGAV-DVSLEQVSGEAQL 762 + EL + I G D L++ L + +Q P ++ V + AQ Sbjct: 669 --AIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLEDTAQF 726 Query: 763 VVRPKRDQLARYGISVDEIMALVSQGVGGASAGQVIDGNARYDIYVRLGEQYRSSPDILE 822 + +++ G+S+ +I +S +GG ID +YV+ ++R P+ ++ Sbjct: 727 KLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRMLPEDVD 786 Query: 823 DLLLTGVSGATVRLGEVADVVIEMAPPNIRRDDVQRRVVVQANVADRDMGSVVNDIYAIV 882 L + +G V P + R + + +Q A G+ D A++ Sbjct: 787 KLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAP---GTSSGDAMALM 843 Query: 883 PQA--ELPPGYTVVVGGQYENQQRAQQKLMLVVPVSIALIALLLFFSFGSVRQVGLIMAN 940 +LP G G ++ + + +V +S ++ L L + S +M Sbjct: 844 ENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLV 903 Query: 941 VPLALIGGVVALFASGTYLSVPSSIGFITLFGVAVLNGVVLVDSINQRRASVKEETDESL 1000 VPL ++G ++A V +G +T G++ N +++V+ E+ + + Sbjct: 904 VPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDL----MEKEGKGV 959 Query: 1001 YDAVYEGTVGRLRPVLMTALTSALGLIPILLSSGVGSEIQQPLAVVIIGGLFSSTALTLL 1060 +A RLRP+LMT+L LG++P+ +S+G GS Q + + ++GG+ S+T L + Sbjct: 960 VEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIF 1019 Query: 1061 VLPTLYRWIYQ 1071 +P + I + Sbjct: 1020 FVPVFFVVIRR 1030 Score = 105 bits (263), Expect = 5e-25 Identities = 79/552 (14%), Positives = 177/552 (32%), Gaps = 70/552 (12%) Query: 10 IRNRLMVVLTLVGLIIACVAMLPKLNLDAFPDVTNVQVTVN-TAAEGLAAEEVEKLI--- 65 + + +L ++ V + +L P+ G E +K++ Sbjct: 534 LGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQV 593 Query: 66 -SYPVESAMYALPAVTEVRSLSRTGLS----IVTVVFAEGTDIYFARQQVFEQLQAAREM 120 Y +++ + +V V S +G + + V + + A+ Sbjct: 594 TDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKME 653 Query: 121 ---IPDGVGVPEIGPNTSGLGQIYQYILRATPESGVDASELRSINDYMVKLIMMPVGGVT 177 I DG +P P LG + ++G+ L + ++ + + Sbjct: 654 LGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLV 713 Query: 178 EVLSFGGEVRQYQVQIEPN--KLLSYGLSMAQVTSALES--NNRNAGGWFMDQGQEQLVV 233 V G Q ++E + K + G+S++ + + + + ++L V Sbjct: 714 SVRP-NGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYV 772 Query: 234 RGYGLLPAGDAGLKAIAQIPLTEVAGTPVRVGDIAKVDYGSEIRVGAVTMTRRDEAGNAQ 293 + + + ++ + G V + G+ + R + + + Sbjct: 773 Q---ADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVY----GSPRLERYNGLPSME 825 Query: 294 DLGEVVAGVVLKRMGANTKETIDDISARTAMIEQALPDGVSFEVFYDQSDLVNQAVTTVR 353 GE G D A + LP G+ ++ + S + Sbjct: 826 IQGEAAPGTSS-----------GDAMALMENLASKLPAGIGYD-WTGMSYQERLSGNQAP 873 Query: 354 DALLMAFVFIVVILALFLVNIRATMLVLLSIPVSIGLALLVMSYFGMSANLMSLGGLAVA 413 + ++FV + + LA + + V+L +P+ I LL + F ++ + GL Sbjct: 874 ALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTT 933 Query: 414 IGMLVDGSVVMVENIFKHLTQPDRRHLANARKRASDEDDPYHADEDGTNTTAHGESSGGI 473 IG+ ++++VE + L + E Sbjct: 934 IGLSAKNAILIVEFA---------KDLMEKEGKGVVE----------------------- 961 Query: 474 TMRVMLAAKEVCSPIFFATAIIIVVFAPLFALEGVEGKLFQPMAVSIILAMISALLVALI 533 ++A + PI + I+ PL G + + ++ M+SA L+A+ Sbjct: 962 --ATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIF 1019 Query: 534 AVPALAVYLFKR 545 VP V + + Sbjct: 1020 FVPVFFVVIRRC 1031 Score = 94.1 bits (234), Expect = 2e-21 Identities = 92/521 (17%), Positives = 191/521 (36%), Gaps = 53/521 (10%) Query: 578 ITAVVMFAMSMML----LPRLGTEFVPELEEGTINLRVTLAPTASLATSLD-VAPKLEAL 632 I A V+ + MM + +L P + +++ P A T D V +E Sbjct: 10 IFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSAN-YPGADAQTVQDTVTQVIEQN 68 Query: 633 LLEFPEVDYALSRIGAAELGGDPEPVNNIEIYIGLKPVDEWVSATNRFELQRKMEAKLNV 692 + + Y S + ++ I + + T+ Q +++ KL + Sbjct: 69 MNGIDNLMYMSST---------SDSAGSVTITLTFQS------GTDPDIAQVQVQNKLQL 113 Query: 693 YPGLLFTFSQPIATRVDELLSGVKAQLAIKIFGPDLDVLSERGQVLTEL---VSQIPGAV 749 LL Q V++ S P V + + +S++ G Sbjct: 114 ATPLLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVG 173 Query: 750 DVSLEQVSGEAQLVVRPKRDQLARYGISVDEIM-ALVSQ----GVGGASAGQVIDGNARY 804 DV L + + + D L +Y ++ +++ L Q G + G + Sbjct: 174 DVQL--FGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQ-QL 230 Query: 805 DIYVRLGEQYRSSPDILEDLLLTGVSGATVRLGEVADVVIEMAPPNIR-RDDVQRRVVVQ 863 + + ++++ + + L G+ VRL +VA V + N+ R + + + Sbjct: 231 NASIIAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLG 290 Query: 864 ANVA-DRDMGSVVNDIYAIVP--QAELPPGYTVVVGGQYENQQRAQQKLMLVVP---VSI 917 +A + I A + Q P G V+ Y+ Q + VV +I Sbjct: 291 IKLATGANALDTAKAIKAKLAELQPFFPQGMKVLY--PYDTTPFVQLSIHEVVKTLFEAI 348 Query: 918 ALIALLLFFSFGSVRQVGLIMANVPLALIGGVVALFASGTYLSVPSSIGFITLFGVAVLN 977 L+ L+++ ++R + VP+ L+G L A G SI +T+FG+ + Sbjct: 349 MLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGY------SINTLTMFGMVLAI 402 Query: 978 GVVLVDSI----NQRRASVKEETDESLYDAVYEGTVGRLRPVLMTALTSALGLIPILLSS 1033 G+++ D+I N R ++++ +A + ++ A+ + IP+ Sbjct: 403 GLLVDDAIVVVENVERVMMEDKLPP--KEATEKSMSQIQGALVGIAMVLSAVFIPMAFFG 460 Query: 1034 GVGSEIQQPLAVVIIGGLFSSTALTLLVLPTLYRWIYQGRK 1074 G I + ++ I+ + S + L++ P L + + Sbjct: 461 GSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVS 501
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 55.6 bits (134), Expect = 5e-11 Identities = 36/182 (19%), Positives = 69/182 (37%), Gaps = 23/182 (12%) Query: 6 KIMVTGASGLLGRALIKQLGQNSQQQI----IACGY------------SRFGPNIERLDL 49 K +VTGA+G +G + K+L + Q + + Y ++ G ++DL Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 50 TQAAQVSSFVAKHKPDIILHCAAERRPDVSEQDPQAALALNSEATQFLTQAASQHG-AWL 108 ++ A + + S ++P A N + + + L Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 109 LYISTDYVFDGSQS-PYREDAETN-PVNFYGQSKLKGELVVSDAQQGFAI----LRLPIL 162 LY S+ V+ ++ P+ D + PV+ Y +K EL+ + + LR + Sbjct: 122 LYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFFTV 181 Query: 163 YG 164 YG Sbjct: 182 YG 183
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 88.0 bits (218), Expect = 7e-23 Identities = 27/111 (24%), Positives = 58/111 (52%), Gaps = 1/111 (0%) Query: 1 MTK-KLLIIEDDIALASVLVRRMTKQGFECQQCHDATQGLLLARQFRPTHLLLDMKLDQE 59 MT +L+ +DD A+ +VL + +++ G++ + +A ++ D+ + E Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 60 NGLKLISPLRQLLPDVVMVLLTGYASIATAVEAIRLGADNYLAKPVDTQTL 110 N L+ +++ PD+ +++++ + TA++A GA +YL KP D L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTEL 111 Score = 47.9 bits (114), Expect = 5e-09 Identities = 27/172 (15%), Positives = 56/172 (32%), Gaps = 20/172 (11%) Query: 8 IEDDIALASVLVRRMTKQGFECQQCHDATQGLLLA-------RQFRPTHLLLDMKLDQEN 60 ED L V++ K+G + ++ L+ A R+ +L+ + Sbjct: 314 AEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELE--NLVRRLTALYPQ 371 Query: 61 GLKLISPLRQLLPDVVMVLLTGYASIATAVEAIRLGADNYLAKPVDTQTLFNALSTTPFD 120 + + L + A+ + +I + + + F Sbjct: 372 DVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFA-----------SFG 420 Query: 121 SMIESLIEEPLSPKRLEWEHIQQVLNANSGNVSATARQLGMHRRTLQRKLLK 172 + +E+ I L A GN A LG++R TL++K+ + Sbjct: 421 DALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRE 472
>MYCMG045#Hypothetical mycoplasma lipoprotein (MG045) signature. Length = 483 Score = 28.9 bits (64), Expect = 0.028 Identities = 24/75 (32%), Positives = 33/75 (44%), Gaps = 7/75 (9%) Query: 64 QPNFSPDSSQLLFTSDRQAAPNSNSQTPAAHNDIYQFQI--ADSHIEQLTFTPEQSEYSP 121 QP SP + LL + +Q SN Q AH I+ + AD EQL T E+ Sbjct: 300 QPKISPVALDLLVINKQQ----SNFQK-EAHEIIFDLALDGADQTKEQLIKTDEELGTDD 354 Query: 122 QAFKTDKATKQITYV 136 + F A + +YV Sbjct: 355 EDFYLKGAMQNFSYV 369
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 56.3 bits (136), Expect = 4e-11 Identities = 75/367 (20%), Positives = 130/367 (35%), Gaps = 54/367 (14%) Query: 1 MKKTLISASVASVLTLASFGALADGPGFYGRLDLAVTNSDT----GATTQNGKSGTVFEN 56 MKK+LI+ ++A++ A YG + V S + GA + ++GT + Sbjct: 1 MKKSLIALTLAALPVAAMADV-----TLYGTIKAGVETSRSVAHNGAQAASVETGTGIVD 55 Query: 57 NFSFVGVKGTESLTNNIDVVYQMEFQVENTTNSGETFKARNTYLGLKSQAGTVLVGRNDH 116 S +G KG E L N + ++Q+E + + + + R +++GLK G + VGR + Sbjct: 56 LGSKIGFKGQEDLGNGLKAIWQVEQKA-SIAGTDSGWGNRQSFIGLKGGFGKLRVGRLNS 114 Query: 117 VFKQS------EGGVDIFGNTNADIDRLVAGQDRVADGIWYYSPKIAGLV-TLNATYLME 169 V K + + D G +A + + Y SP+ AGL ++ Sbjct: 115 VLKDTGDINPWDSKSDYLGVNK------IAEPEARLISVRYDSPEFAGLSGSVQYALNDN 168 Query: 170 DNYIDADDKDAVASYD-----AQYALSATIGDKKLKEQNYYVAAAYNTIKGIDAYRGVAQ 224 +++ A +Y QY + + + N + + G D A Sbjct: 169 AGRHNSESYHAGFNYKNGGFFVQYGGAYKRHHQVQENVNIEKYQIHRLVSGYDNDALYAS 228 Query: 225 V--KLGDFKVGGLFQNTESQTTDQEGNSYFVNVAYNLNGVNLKAEYGMDEGGFGKYYQNS 282 V + D K+ + SQ +AY V + Y GF + Sbjct: 229 VAVQQQDAKLVEENYSHNSQ------TEVAATLAYRFGNVTPRVSYAH---GFKGSFDA- 278 Query: 283 VPKVDGSKVIGTDINVQVITVGADYKISKSTMVYGHYAMYEGDHKVAGNKFDLKDDNVFT 342 + + + VGA+Y SK T + G Sbjct: 279 ---------TNYNNDYDQVVVGAEYDFSKRTSALVSAGWLQE-----GKGESKFVSTAGG 324 Query: 343 VGLRYNF 349 VGLR+ F Sbjct: 325 VGLRHKF 331
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 61.4 bits (149), Expect = 1e-12 Identities = 68/364 (18%), Positives = 121/364 (33%), Gaps = 44/364 (12%) Query: 1 MKKTVLSATIISALAATSFTALADGPNFYGRADLAITNSDM----GIATQNQKSGTVIEN 56 MKK++++ T+ + A YG + S G + ++GT I + Sbjct: 1 MKKSLIALTLAALPVAAMADV-----TLYGTIKAGVETSRSVAHNGAQAASVETGTGIVD 55 Query: 57 NFSWLGVKGTEAINSELEVVYQMEFGVNNFDNSGNTFSARNTFLGLKSATAGTILVGRND 116 S +G KG E + + L+ ++Q+E + + R +F+GLK G + VGR + Sbjct: 56 LGSKIGFKGQEDLGNGLKAIWQVEQKASIAGTDSGWGN-RQSFIGLK-GGFGKLRVGRLN 113 Query: 117 TVFK------ASEGGFDIFGNTNSDIDLFAAGQSRNADGFTYYSPKIAGLVTLNATYLMD 170 +V K + D G ++ A ++R Y SP+ AGL Sbjct: 114 SVLKDTGDINPWDSKSDYLG-----VNKIAEPEARLI-SVRYDSPEFAGLS-------GS 160 Query: 171 DNYAQEVDGKKVDTDNMYALSATIGDKGLKAQNYYVAAAYNDSIDNVKAYRGVAQVKLGQ 230 YA + + ++++ Y + G Q ++ +NV + Sbjct: 161 VQYALNDNAGRHNSES-YHAGFNYKNGGFFVQYGGAYKRHHQVQENVNIEKYQIHR---- 215 Query: 231 VILGGFYQNSEHVDSKYANLEGDTYFVNAAYVMGDLKLKAMYGSDDSGLGKYVSRYVGSV 290 L Y N S + ++ A + VS Y Sbjct: 216 --LVSGYDNDALYASVAVQQQDAKLVEENYSHNSQTEVAATLAYRFGNVTPRVS-YAHGF 272 Query: 291 DGATLENVSDVDL-QQFSVGADYRLSKNTLVYGHYTKYDGDIKLAGATQDLSDDIFTVGM 349 + + + + Q VGA+Y SK T + VG+ Sbjct: 273 -KGSFDATNYNNDYDQVVVGAEYDFSKRTSALVSAGWLQEGKGESKFVS----TAGGVGL 327 Query: 350 RFDF 353 R F Sbjct: 328 RHKF 331
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 38.7 bits (90), Expect = 4e-05 Identities = 58/379 (15%), Positives = 128/379 (33%), Gaps = 41/379 (10%) Query: 55 FFPNYDTTSALMATFAIFAIS-FIVRPLGGIFWGHIGDKIGRKTALSMSIIIMSCATFCI 113 + D T+ A++A+ F P+ G + D+ GR+ L +S+ + + Sbjct: 35 LVHSNDVTAHYGILLALYALMQFACAPVLG----ALSDRFGRRPVLLVSLAGAAVDYAIM 90 Query: 114 ALLPDYNSIGIMAPLLLLVARMFQGFSASGEYAGAATFLTEIAPKEEKGFYASIVPASAA 173 A P +L + R+ G + A A ++ +I +E+ + + A Sbjct: 91 ATAP--------FLWVLYIGRIVAGITG-ATGAVAGAYIADITDGDERARHFGFMSACFG 141 Query: 174 AGLLFGSIFISILYAFLSSAQLHEWGWRIPFLLAAPFGLIGLYIRVKIEDSPQFVKFKEE 233 G++ G + + + PF AA + + + + Sbjct: 142 FGMVAGPVL---------GGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPL 192 Query: 234 NKEKQSP---IPLQVILAHHKKPLLLGFLVTSLNALGFYLLLSYMPTYMTVHLEVKDTT- 289 +E +P + + + F++ + + L + + H + Sbjct: 193 RREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIF--GEDRFHWDATTIGI 250 Query: 290 AFAISSIVLAFYILFVFSIGKLSDKFGRRKLLMLASLCFICLSIPIFIILESANIFQMTL 349 + A I+ + + G ++ + G R+ LML + I + F + + Sbjct: 251 SLAAFGILHSLAQAMIT--GPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMV 308 Query: 350 VLILFSAFLALNDGCLSCYLCELFPTNVRYTGFALSFNSANALFGGTAPFIATTLIAVT- 408 +L + LS + E + G + S ++ G P + T + A + Sbjct: 309 LLASGGIGMPALQAMLSRQVDE--ERQGQLQGSLAALTSLTSIVG---PLLFTAIYAASI 363 Query: 409 ----GLSYAPGFYLMLIAL 423 G ++ G L L+ L Sbjct: 364 TTWNGWAWIAGAALYLLCL 382 Score = 34.8 bits (80), Expect = 6e-04 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 7/89 (7%) Query: 252 KPLLLGFLVTSLNALGFYLLLSYMPTYMTVHLEVKDTTAFAISSIVLAFYIL--FVFS-- 307 +PL++ +L+A+G L++ +P + V A I+LA Y L F + Sbjct: 5 RPLIVILSTVALDAVGIGLIMPVLPGLLRDL--VHSNDVTAHYGILLALYALMQFACAPV 62 Query: 308 IGKLSDKFGRRKLLMLASLCFICLSIPIF 336 +G LSD+FGRR ++L SL + I Sbjct: 63 LGALSDRFGRR-PVLLVSLAGAAVDYAIM 90
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 40.6 bits (95), Expect = 6e-06 Identities = 15/95 (15%), Positives = 31/95 (32%), Gaps = 3/95 (3%) Query: 214 GRILWVDDHPENNLVEKAFFEQKGIGVYSTVTSEEALMLLSMYHYQAVISDMGRHGDSLA 273 IL DD V + G V T + ++ V++D+ ++ Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN-- 61 Query: 274 GLKLLQSIRASGNKTPFYLYT-YVESAGVVDAIDE 307 LL I+ + P + + + A ++ Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEK 96
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 35.2 bits (81), Expect = 4e-04 Identities = 37/180 (20%), Positives = 70/180 (38%), Gaps = 3/180 (1%) Query: 12 NWAPVWLLALTAFVFVSTEFVPVGILAALGQSFNMSAVAVGPMLTVYAAVVALASLPAVL 71 N +WL L+ F ++ + V L + FN + + T + ++ + Sbjct: 13 NQILIWLCILSFFSVLNEMVLNVS-LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGK 71 Query: 72 LFARFERKKLLLGIMAVFIISHGICVWAPSY-DILLSGRIGIALTHALFWAIAPALVVRL 130 L + K+LLL + + I S+ +L+ R A F A+ +V R Sbjct: 72 LSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARY 131 Query: 131 APEGQGAKALSIFATGCVLALVLGIPLGRVIGQLIGWRSIFALIGLLTFAMMLLLWRGLP 190 P+ KA + + + +G +G +I I W + LI ++T + L + L Sbjct: 132 IPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLL-LIPMITIITVPFLMKLLK 190
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 35.3 bits (81), Expect = 3e-05 Identities = 17/60 (28%), Positives = 24/60 (40%), Gaps = 2/60 (3%) Query: 70 LINVVWVDESARGTGLGRDLMQRAEVEAKQRGCTMAQLDTLSFQAPV--FYQKLGFEIIG 127 LI + V + R G+G L+ +A AK+ L+T FY K F I Sbjct: 91 LIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGA 150
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 39.4 bits (92), Expect = 7e-05 Identities = 42/215 (19%), Positives = 78/215 (36%), Gaps = 21/215 (9%) Query: 696 RIDSDIKQLQGQ-QQEWLEEQKEQALEARMEKNAYWQEVVGALDSQLNQVKSNIQSRRDH 754 ++D + Q Q LE+ + Q L +E N E+ + V R Sbjct: 131 GAEADTLKTQSSLLQARLEQTRYQILSRSIELNKL-PELKLPDEPYFQNVSEEEVLRLTS 189 Query: 755 AASEQKACEQWYKNELKSRGVDEAKIVALKAEIRTLESSISKAEQRRSEVLRYEDWYQHT 814 EQ + Q K + E + +AE T+ + I++ E S V + Sbjct: 190 LIKEQFSTWQNQKYQK------ELNLDKKRAERLTVLARINRYENL-SRVEKSR------ 236 Query: 815 WLKRKPKLQSELSKVKHASLDLEQQLKSKANEVKAKRNELDGERKRSDVVQIEASENLTK 874 L L + + KHA L+ E + NE++ +++L+ + E Sbjct: 237 -LDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQL 295 Query: 875 LRSVMRKLSELKLPASNDDAQGSLTERLRQGEDQL 909 ++ + KL + D+ LT L + E++ Sbjct: 296 FKNEILD----KLRQTTDNIG-LLTLELAKNEERQ 325
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 34.8 bits (80), Expect = 2e-04 Identities = 27/123 (21%), Positives = 38/123 (30%), Gaps = 17/123 (13%) Query: 111 AAVNASLERLQIDTIDLY----QIHWPDRNTNFFGELSYNQQDEHEKLTPIIDTLEALSD 166 V SL + LY + HW + +FF HEK + D D Sbjct: 11 TLVENSLNTQLSNWFLLYSKLHRFHWYVKGPHFF--------TLHEKFEELYDHAAETVD 62 Query: 167 LIKAGKIRYIGISNETPWGFM-EYLRLAEKHDLPKIVSVQNPYNLLNRSYEVGMAEISHR 225 I A ++ IG P + EY A D S L Y+ +E Sbjct: 63 TI-AERLLAIGGQ---PVATVKEYTEHASITDGGNETSASEMVQALVNDYKQISSESKFV 118 Query: 226 EEV 228 + Sbjct: 119 IGL 121
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.8 bits (85), Expect = 4e-05 Identities = 14/49 (28%), Positives = 18/49 (36%) Query: 240 PEVRGKGFAKRLALQAIRYANVQGYTSCYLETTANLIEAIKLYESLGFK 288 + R KG L +AI +A + LET I A Y F Sbjct: 99 KDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFI 147
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 29.5 bits (66), Expect = 0.004 Identities = 9/24 (37%), Positives = 14/24 (58%) Query: 70 QLAILTGMLVHPDYRGQGVGHRLM 93 A++ + V DYR +GVG L+ Sbjct: 88 GYALIEDIAVAKDYRKKGVGTALL 111
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 26.7 bits (59), Expect = 0.046 Identities = 15/85 (17%), Positives = 33/85 (38%), Gaps = 2/85 (2%) Query: 82 DTKIGVKFGDDYLGFHPYLTVAYGEGKATIYNYSGDDNYIFVGAGAEVQIAKNYVISAEF 141 T++ + P ++ A+G + + +++Y V GAE +K Sbjct: 248 QTEVAATLAYRFGNVTPRVSYAHGFKG-SFDATNYNNDYDQVVVGAEYDFSKRTSALVSA 306 Query: 142 GNLKLDE-LSEISANVTRINFAYKF 165 G L+ + S+ + + +KF Sbjct: 307 GWLQEGKGESKFVSTAGGVGLRHKF 331
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 67.5 bits (165), Expect = 3e-14 Identities = 64/308 (20%), Positives = 108/308 (35%), Gaps = 36/308 (11%) Query: 71 SDYGIIIAIWAFMQTFIPVFTGGISDRVGYKETIFASTIIKIAGYLVMAFFPSFYGFLFG 130 + YGI++A++A MQ G +SDR G + + S Y +MA P + L+ Sbjct: 43 AHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLW-VLYI 101 Query: 131 AILLAGGTGIFKPGIQGTLVLSTGRQNTSMAWGIFYQVVNIGGFLGPLVAVHMRQLSWDN 190 ++AG TG + T + +G G GP++ M S Sbjct: 102 GRIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHA 161 Query: 191 VFYACAAIISLNFLF-LLAYKEPGKEERMERNRKIKAGEIHQEALWRDALHELKKPIVIY 249 F+A AA+ LNFL E K ER R+ AL+ L Sbjct: 162 PFFAAAALNGLNFLTGCFLLPESHKGERRPLRRE--------------ALNPLASFRWAR 207 Query: 250 YMLVFAGFWFLFNSLFDVLPIHISEWVDTSVIVTSLFGPDGTSNGFFQFWLGLDNTGTKV 309 M V A +F + V + + WV + F D T+ G G+ + Sbjct: 208 GMTVVAALMAVFFIMQLVGQVPAALWV---IFGEDRFHWDATTIGISLAAFGILH----- 259 Query: 310 MPEGMLNLNAGMIMTTCFLVAALTAKYRITTAMLAGCLLSILAFVLIGATNAAWMIVLAI 369 + + + A+ A++ G + ++L+ WM + Sbjct: 260 ------------SLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIM 307 Query: 370 AMFSFGEM 377 + + G + Sbjct: 308 VLLASGGI 315 Score = 50.6 bits (121), Expect = 8e-09 Identities = 34/145 (23%), Positives = 62/145 (42%), Gaps = 10/145 (6%) Query: 66 LGISLSDYGIIIAIWAFMQTFIPVFTGGISDRVGYKETIFASTIIKIAGYLVMAFFPSFY 125 +GISL+ +GI+ ++ + TG ++ R+G + + I GY+++AF + Sbjct: 248 IGISLAAFGILHSL------AQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGW 301 Query: 126 GFLFGAILLAGGTGIFKPGIQGTLVLSTGRQNTSMAWGIFYQVVNIGGFLGPLVAVHMRQ 185 +LLA G GI P +Q L + G + ++ +GPL+ + Sbjct: 302 MAFPIMVLLASG-GIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYA 360 Query: 186 LS---WDNVFYACAAIISLNFLFLL 207 S W+ + A + L L L Sbjct: 361 ASITTWNGWAWIAGAALYLLCLPAL 385
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 28.7 bits (64), Expect = 0.023 Identities = 11/50 (22%), Positives = 17/50 (34%), Gaps = 7/50 (14%) Query: 98 LLIGY-------PMAYAIARAPKRNQTMLILLVMLPSWTSFLIRVYAWMG 140 +LIGY P A R + +L+ + F I V + Sbjct: 120 ILIGYSFGAEVIPFVLNEMPARYRKNVLGAVLLSPSQSSDFEIHVSEMVT 169
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 26.7 bits (59), Expect = 0.011 Identities = 8/24 (33%), Positives = 14/24 (58%) Query: 3 KHLGVAAVLVVLLILIFGCSQRSA 26 K L A +LV L++ +F + R+ Sbjct: 342 KTLFEAIMLVFLVMYLFLQNMRAT 365
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 26.7 bits (59), Expect = 0.021 Identities = 7/24 (29%), Positives = 14/24 (58%) Query: 18 LAEELGNVSRACKVMGVSRDTFYR 41 L GN +A ++G++R+T + Sbjct: 445 LTATRGNQIKAADLLGLNRNTLRK 468
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 49.9 bits (119), Expect = 3e-10 Identities = 20/56 (35%), Positives = 35/56 (62%) Query: 2 TKKTFGFSLIELVVVLVILGVLSVIVIPRFINLHRDAKIATLKATKGSIESAFDMF 57 T K GF+L+E++VV+VI+GVL+ +V+P + A + ++E+A DM+ Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMY 59
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 29.8 bits (67), Expect = 0.005 Identities = 13/52 (25%), Positives = 25/52 (48%), Gaps = 1/52 (1%) Query: 112 LQIEKANVQIENTEKQILETQQKNKTDLYLAHYKHFSEHLVALEAKWKNTVN 163 L +E + +N KQ+ NK + Y + K +++ L L+ + K+ N Sbjct: 142 LNLENGIIFAKNIAKQLSAKDPNNK-EFYEKNLKEYTDKLDKLDKESKDKFN 192
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 26.1 bits (57), Expect = 0.040 Identities = 9/24 (37%), Positives = 12/24 (50%) Query: 102 EVEPEPEPEPQSPVRKGPTRKGPG 125 E EP PEP ++PV + P Sbjct: 74 EPEPIPEPPKEAPVVIEKPKPKPK 97
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 26.3 bits (58), Expect = 0.015 Identities = 9/30 (30%), Positives = 17/30 (56%) Query: 49 TLSPSAQAASAIVSELARALSPTQRQQLQQ 78 T +P++ AA+ ++ LS ++QL Q Sbjct: 176 TTTPASMAATLRKLLTSQRLSARSQRQLLQ 205
>PF05043#Transcriptional activator Length = 493 Score = 29.5 bits (66), Expect = 0.009 Identities = 9/62 (14%), Positives = 20/62 (32%), Gaps = 10/62 (16%) Query: 55 DGKSFAP--RKKNSESKSLKRLAKGLKPYVTGGNRLELK-HKNKLTGR-------IAAFH 104 +G ++ S SL R+ + + + E+ ++ G A + Sbjct: 99 EGCQAESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYF 158 Query: 105 QE 106 E Sbjct: 159 SE 160
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 27.2 bits (60), Expect = 0.021 Identities = 14/70 (20%), Positives = 31/70 (44%) Query: 40 LKDFTDAVKASQKLNEMEKKQIRDFIEDNMDIVKEGLESWIEGVEGISSAERCIQKMFSG 99 ++F +S K++E+ KKQ + ++ K +E + V+ ++S + Sbjct: 149 FQNFLGTALSSMKIDELIKKQKSGGNVSSSELAKASIELINQLVDTVASLNNNVNSFSQQ 208 Query: 100 LSELATFSEN 109 L+ L + N Sbjct: 209 LNTLGSVLSN 218
>FLAGELLIN#Flagellin signature. Length = 507 Score = 132 bits (333), Expect = 1e-37 Identities = 95/271 (35%), Positives = 134/271 (49%), Gaps = 10/271 (3%) Query: 2 AITVNTNVTSMKAQKNLNASSQNLATSMERLSSGLRINSAKDDAAGLAISNRLDSQVRGL 61 A +NTN S+ Q NLN S +L++++ERLSSGLRINSAKDDAAG AI+NR S ++GL Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 DVGMRNANDAISIAQISEGAMQEQTNMLQRMRDLTIQASNGANSSDDIASIKKEIDALAG 121 RNAND ISIAQ +EGA+ E N LQR+R+L++QA+NG NS D+ SI+ EI Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 EITSIGNTTAFGNTKLMNGDFSAGKSFQVGHQKGEDITVKVQKVNASSLAVGSL------ 175 EI + N T F K+++ D QVG GE IT+ +QK++ SL + Sbjct: 121 EIDRVSNQTQFNGVKVLSQDNQ--MKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPK 178 Query: 176 --TLTNSANRQSALTKIDAAIKTIDSQRADLGAVQNRLSHNISNSANTQANVADAKSRIV 233 T+ + + +T D + R D+ + + A Sbjct: 179 EATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTT 238 Query: 234 DVDFAKETAAMTKNQVLQQTGSAMLAQANQL 264 D + K + A A + Sbjct: 239 DDAENNTAVDLFKTTKSTAGTAEAKAIAGAI 269 Score = 87.0 bits (215), Expect = 2e-21 Identities = 57/213 (26%), Positives = 97/213 (45%), Gaps = 4/213 (1%) Query: 60 GLDVGMRNANDAISIAQISEGAMQEQTNMLQRMRDLTIQASNGANSSDDIASIKKEIDAL 119 + + +++A I+ GA LQ +++ NG + DD + + Sbjct: 298 KVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSD 357 Query: 120 AGEITSIGNTTAFGNTKLMNGDFSAGKSFQVGHQKGEDITVKVQKVNASSLAVGSLTLTN 179 ++ + +AG + + + + S + Sbjct: 358 LEANNAVKGESKITVNGAEYTANAAGDKVTLAGK----TMFIDKTASGVSTLINEDAAAA 413 Query: 180 SANRQSALTKIDAAIKTIDSQRADLGAVQNRLSHNISNSANTQANVADAKSRIVDVDFAK 239 + + L ID+A+ +D+ R+ LGA+QNR I+N NT N+ A+SRI D D+A Sbjct: 414 KKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYAT 473 Query: 240 ETAAMTKNQVLQQTGSAMLAQANQLPQVALSLL 272 E + M+K Q+LQQ G+++LAQANQ+PQ LSLL Sbjct: 474 EVSNMSKAQILQQAGTSVLAQANQVPQNVLSLL 506
>SHIGARICIN#Ribosome inactivating protein family signature. Length = 289 Score = 29.4 bits (66), Expect = 0.025 Identities = 10/59 (16%), Positives = 19/59 (32%), Gaps = 6/59 (10%) Query: 276 NTLVESISNLSKYDTEKEEAAALQGDSMI------RSIESQMRNMISNRVDVDGETIAL 328 L +I+ L Y+ +A + + IE Q+ + I+L Sbjct: 153 PALDSAITTLFYYNANSAASALMVLIQSTSEAARYKFIEQQIGKRVDKTFLPSLAIISL 211
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 436 bits (1124), Expect = e-152 Identities = 166/478 (34%), Positives = 256/478 (53%), Gaps = 17/478 (3%) Query: 7 RILLVGNQSERINRLSCVFEFLGEQVELIDFDKLELHTKQTRFRAIVLPSENQPK----E 62 IL+ + + L+ G V + +V+ P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 63 LIQSLTGMLPWQPFLTLGERDDIKA------SNILGCIEEPLNYPQLTELLHFCQVYGQV 116 L+ + P P L + ++ + +P + +L ++ + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 117 KRPEIPTSANQTKLFRSLVGRSEGIASVRHLINQVSGSEATVLVLGQSGTGKEVVARNIH 176 + ++ + LVGRS + + ++ ++ ++ T+++ G+SGTGKE+VAR +H Sbjct: 125 RPSKLEDDSQD---GMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALH 181 Query: 177 YISDRRDGPFIPVNCGAIPAELLESELFGHEKGSFTGAISARKGRFELAEKGTLFLDEIG 236 RR+GPF+ +N AIP +L+ESELFGHEKG+FTGA + GRFE AE GTLFLDEIG Sbjct: 182 DYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIG 241 Query: 237 DMPLQMQVKLLRVLQERMFERVGGSKSIAADVRVVAATHRNLETMIEEGGFREDLYYRLN 296 DMP+ Q +LLRVLQ+ + VGG I +DVR+VAAT+++L+ I +G FREDLYYRLN Sbjct: 242 DMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLN 301 Query: 297 VFPIEMPALCERKEDIPLLLQELVSRVYNEGRGRVRFTQRAIESLKEHAWSGNVRELSNL 356 V P+ +P L +R EDIP L++ V + EG RF Q A+E +K H W GNVREL NL Sbjct: 302 VVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELENL 361 Query: 357 VERLTILYPGGLVDVNDLPIKYRHIDVPEYCVEISEEQQERDALASIFNDEEPIEIPETR 416 V RLT LYP ++ + + R ++P+ +E + + +++ EE + Sbjct: 362 VRRLTALYPQDVITREIIENELRS-EIPDSPIEKAAARSGSLSISQAV--EENMRQYFAS 418 Query: 417 FPSELPPEGVNLKDLLAELEIDMIRQALDQQDNVVARAAEMLGIRRTTLVEKMRKYGM 474 F LPP G+ +LAE+E +I AL +AA++LG+ R TL +K+R+ G+ Sbjct: 419 FGDALPPSGL-YDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGV 475
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 467 bits (1202), Expect = e-164 Identities = 170/483 (35%), Positives = 250/483 (51%), Gaps = 39/483 (8%) Query: 1 MSEGKLLLVEDDASLREALLDTLMLAHYDCVDVGSAEEAILALKADRFDLVISDVQMEGI 60 M+ +L+ +DDA++R L L A YD +A + A DLV++DV M Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 GGIGLLNYLQQHQPKLPVLLMTAYATIDNAVNAMKLGAVDYLAKPFSPEVLLNQVSRYL- 119 LL +++ +P LPVL+M+A T A+ A + GA DYL KPF L+ + R L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 120 ---------PAKAAEGTPIVADEKSL-ALLALAQRVAASDASVMIMGPSGSGKEVLARFI 169 + +G P+V ++ + + R+ +D ++MI G SG+GKE++AR + Sbjct: 121 EPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARAL 180 Query: 170 HQNSQRAEQPFIAINCAAIPENMLEATLFGYEKGAFTGAYQACPGKFEQAQGGTLLLDEI 229 H +R PF+AIN AAIP +++E+ LFG+EKGAFTGA G+FEQA+GGTL LDEI Sbjct: 181 HDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEI 240 Query: 230 SEMEVGLQAKLLRVLQEREVERLGGRKTIKLDVRVLATSNRDLKAMAASGEFREDLYYRI 289 +M + Q +LLRVLQ+ E +GGR I+ DVR++A +N+DLK G FREDLYYR+ Sbjct: 241 GDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRL 300 Query: 290 NVFPLTWPSLNQRPADILPLARHLLQRHALIANRSELPLLSECASRRLLTHRWPGNVREL 349 NV PL P L R DI L RH +Q+ ++ + A + H WPGNVREL Sbjct: 301 NVVPLRLPPLRDRAEDIPDLVRHFVQQAE--KEGLDVKRFDQEALELMKAHPWPGNVREL 358 Query: 350 DNVVQRALIMCGSHEITAADIIID--SLELDFNLESTPLAD------------------- 388 +N+V+R + IT I + S D +E Sbjct: 359 ENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFAS 418 Query: 389 --NKPTELDGLGDELKAQEHVIILETLTQCNGSRKLVAEKLGISARTLRYKMAKMRDSGI 446 + L E+ +IL LT G++ A+ LG++ TLR K+ ++ G+ Sbjct: 419 FGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIREL---GV 475 Query: 447 QIP 449 + Sbjct: 476 SVY 478
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 53.9 bits (129), Expect = 6e-13 Identities = 28/71 (39%), Positives = 44/71 (61%) Query: 40 FGQLLSQAVGNVSELQSNASNLATRLDMGDTTVTLSDTVIAREKSSVAFEATVQVRNKLV 99 F L A+ +S+ Q+ A A + +G+ V L+D + +K+SV+ + +QVRNKLV Sbjct: 33 FAGQLHAALDRISDTQTAARTQAEKFTLGEPGVALNDVMTDMQKASVSMQMGIQVRNKLV 92 Query: 100 EAYKEIMSMPV 110 AY+E+MSM V Sbjct: 93 AAYQEVMSMQV 103
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 301 bits (773), Expect = 1e-97 Identities = 150/562 (26%), Positives = 257/562 (45%), Gaps = 47/562 (8%) Query: 30 LGGVDMLRQVTMILALAICLALAVFVMIWAQEPEYRPL-GQMSTAEMVQVLDVLDNNQVK 88 L + ++ +I+A + +A+ V +++WA+ P+YR L +S + ++ L + Sbjct: 16 LNRLRANPRIPLIVAGSAAVAIVVAMVLWAKTPDYRTLFSNLSDQDGGAIVAQLTQMNIP 75 Query: 89 YEIQGD--VVKVPEDKFQDVRMLLSREGLDNTDANNDFLNKDSGFGVSQRMEQARLKHSQ 146 Y ++VP DK ++R+ L+++GL A L FG+SQ EQ + + Sbjct: 76 YRFANGSGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQFSEQVNYQRAL 135 Query: 147 EQNLARIIEELKSVTRAKVILALPKENVFARNRSKPSATVVVSTRRS-GLSQEEVDSIVD 205 E LAR IE L V A+V LA+PK ++F R + PSA+V V+ L + ++ ++V Sbjct: 136 EGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLEPGRALDEGQISAVVH 195 Query: 206 IVASAVHNLEPNKVTVTDANGRLLNSGTQDGSSAIARRELEIVQQKESEYRNKVESILMP 265 +V+SAV L P VT+ D +G LL G +L+ ES + ++E+IL P Sbjct: 196 LVSSAVAGLPPGNVTLVDQSGHLLTQSNTSGRDL-NDAQLKFANDVESRIQRRIEAILSP 254 Query: 266 ILGPENFTSQVDVSMDFTAVEQTAKRYNPDLPSLRSEMVVENNS-----NGGTSGGIPGA 320 I+G N +QV +DF EQT + Y+P+ + ++ + + G GG+PGA Sbjct: 255 IVGNGNVHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQVGAGYPGGVPGA 314 Query: 321 LSNQPP---------------MASDIPQEVNAEETVTRNSGSTHKEATRNFELDTTISHT 365 LSNQP A + PQ + + + ST + T N+E+D TI HT Sbjct: 315 LSNQPAPPNEAPIATPPTNQQNAQNTPQTSTSTNSNSAGPRSTQRNETSNYEVDRTIRHT 374 Query: 366 RQQIGTLRRVSVSVAVDFKNAPMAEDGSVNRVPRTEQELANIRRLLEGAVGFNTQRGDVI 425 + +G + R+SV+V V++K + +P T ++ I L A+GF+ +RGD + Sbjct: 375 KMNVGDIERLSVAVVVNYKTLADGKP-----LPLTADQMKQIEDLTREAMGFSDKRGDTL 429 Query: 426 EVVTVPFMDQLIEAAPAPELWEQPWFWRVLRLVLGALVILVLILAVVRPMLKKLVYPDSV 485 VV PF + W+Q F L L++LV+ + R ++ + Sbjct: 430 NVVNSPF-SAVDNTGGELPFWQQQSFIDQLLAAGRWLLVLVVAWILWRKAVRPQLTRRVE 488 Query: 486 NMPDEPQRGGELAEIEDQYAADTLGMLQRPEAEYSYADDGSIL---IPNLHKDDDMIKAI 542 ++ E E+ E + D + + M + I Sbjct: 489 EAKAAQEQAQVRQETEE-------------AVEVRLSKDEQLQQRRANQRLGAEVMSQRI 535 Query: 543 RALVANEPELSTQVVKNWLLED 564 R + N+P + V++ W+ D Sbjct: 536 REMSDNDPRVVALVIRQWMSND 557
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 287 bits (736), Expect = 1e-97 Identities = 108/341 (31%), Positives = 187/341 (54%) Query: 8 EAKTAPGFKPSELNGIEKTAILLLSLSESDAASILKYLEPKQVQKVGMAMAAMRDFGQEK 67 E K S L G +K AILL+S+ ++ + KYL ++++ + +A + E Sbjct: 3 EKKEKEILDVSALTGKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKLETITSEL 62 Query: 68 VIGVHKLFLDDIQKYSSIGFNSEEFVRKALTAALGEDKAGNLIEQIIMGSGAKGLDSLKW 127 V F + + I ++ R+ L +LG KA ++I + ++ + ++ Sbjct: 63 KDNVLLEFKELMMAQEFIQKGGIDYARELLEKSLGTQKAVDIINNLGSALQSRPFEFVRR 122 Query: 128 MDARQVATIIQNEHPQIQTIVLSYLEPDQAAEIFAQFPENTRLDLMMRIANLEEVQPAAL 187 D + IQ EHPQ ++LSYL+P +A+ I + P + ++ RIA ++ P + Sbjct: 123 ADPANILNFIQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVV 182 Query: 188 QELNDIMEKQFAGQGGAQAAKMGGLKAAANIMNYLDTGVESHLMETMRESDEEMAQQIQD 247 +E+ ++EK+ A GG+ I+N D E ++E++ E D E+A++I+ Sbjct: 183 REVERVLEKKLASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPELAEEIKK 242 Query: 248 LMFVFENLSDVDDMGIQVLLREVQQDVLMKALKGADEQLKEKLLGNMSKRAAELLRDDLE 307 MFVFE++ +DD IQ +LRE+ L KALK D ++EK+ NMSKRAA +L++D+E Sbjct: 243 KMFVFEDIVLLDDRSIQRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRAASMLKEDME 302 Query: 308 AMGPIRISEVEVAQKEILSIARRLSDSGEIMLGGGGGEEFL 348 +GP R +VE +Q++I+S+ R+L + GEI++ GG E+ L Sbjct: 303 FLGPTRRKDVEESQQKIVSLIRKLEEQGEIVISRGGEEDVL 343
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 79.8 bits (196), Expect = 1e-19 Identities = 54/198 (27%), Positives = 97/198 (48%), Gaps = 4/198 (2%) Query: 50 PLETETILPPTLSEIEDIRAHAEQEGFA---EGQEKGFTEGLEKGRLEGLEQGHGEGYSQ 106 E I+ P + IE+ EQ+ + E+G+ G+ +GR +G +QG+ EG +Q Sbjct: 19 QAEFVPIVEPEETIIEEAEPSLEQQLAQLQMQAHEQGYQAGIAEGRQQGHKQGYQEGLAQ 78 Query: 107 GQQQGYEEGLKTAAEMLQRFENLLGQFEAPLALLDTEIEKELLTTSMTLAKAVIGHELKT 166 G +QG E A + R + L+ +F+ L LD+ I L+ ++ A+ VIG Sbjct: 79 GLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRLMQMALEAARQVIGQTPTV 138 Query: 167 YPEHILSALRQGVDSLPIKEQRVNIRVTPSDEALIGELYSQTQLERNRWQIEADPSLSPG 226 ++ ++Q + P+ + +RV P D + ++ T L + W++ DP+L PG Sbjct: 139 DNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGAT-LSLHGWRLRGDPTLHPG 197 Query: 227 DCIIDSVRSHIDMTVETR 244 C + + +D +V TR Sbjct: 198 GCKVSADEGDLDASVATR 215
>FLGFLIJ#Flagellar FliJ protein signature. Length = 147 Score = 39.8 bits (92), Expect = 7e-07 Identities = 38/145 (26%), Positives = 71/145 (48%) Query: 1 MAKPDPLHMVLKLTQDAEEQASLQLRSAQLELQRRQNQLEALQNYRLDYMKQMEQQQGQS 60 MA+ L + L + E A+ L + Q+ + QL+ L +Y+ +Y + Sbjct: 1 MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAG 60 Query: 61 ISASHYHQFHQFVRQVDAAIVQQVNAVKDADNQRQHRQVYWQEKQQKRKAVELLLANKAE 120 I+++ + + QF++ ++ AI Q + + W+EK+Q+ +A + L ++ Sbjct: 61 ITSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQST 120 Query: 121 KAKLAELRAEQKMVDEFASQQFYRK 145 A LAE R +QK +DEFA + RK Sbjct: 121 AALLAENRLDQKKMDEFAQRAAMRK 145
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 45.6 bits (107), Expect = 3e-07 Identities = 30/109 (27%), Positives = 52/109 (47%), Gaps = 1/109 (0%) Query: 376 MNQQLITMVSNGVQHAEIRLDPPELGHMMVRIQVQGDTTQVQFQVSQHQTRDLVEQAMPR 435 ++Q + G Q AE+RL P +LG + + ++V + Q+Q R +E A+P Sbjct: 244 LSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMVSPHQHVRAALEAALPV 303 Query: 436 LREMLAEQGMQLTDGQVSQGSGGNSDGEQGSGRGNDNGMAETDEISAEE 484 LR LAE G+QL +S G + + S + A + ++ E+ Sbjct: 304 LRTQLAESGIQLGQSNIS-GESFSGQQQAASQQQQSQRTANHEPLAGED 351
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 249 bits (638), Expect = 4e-83 Identities = 86/326 (26%), Positives = 168/326 (51%), Gaps = 11/326 (3%) Query: 1 MSDLLSQDEIDALLHGVDDVEEDIID----DNELDARSYDFSSQDRIVRGRMPTLEIVNE 56 M+++LSQDEID LL + + I D + YDF D+ + +M TL +++E Sbjct: 1 MTEVLSQDEIDQLLTAISSGDASIEDARPISDTRKITLYDFRRPDKFSKEQMRTLSLMHE 60 Query: 57 RFARHLRISMFNMMRRAAEVSINGVQMLKFGEYVHTLFVPTSLNMVRFSPLKGTALITME 116 FAR S+ +R V + V L + E++ ++ P++L ++ PLKG A++ ++ Sbjct: 61 TFARLTTTSLSAQLRSMVHVHVASVDQLTYEEFIRSIPTPSTLAVITMDPLKGNAVLEVD 120 Query: 117 ARLVFILVDNFFGGDGRFHAKIEGREFTPTERRIVQLLLKIIFEDYKDAWAPVMDVQFDY 176 + F ++D FGG G+ R+ T E +++ ++ I + +++W V+D++ Sbjct: 121 PSITFSIIDRLFGGTGQAAKVQ--RDLTDIENSVMEGVIVRILANVRESWTQVIDLRPRL 178 Query: 177 LDSEVNPAMANIVSPTEVVVVSSFHIEVDGGGGDFHITMPYSMIEPIRELLDAG--VQSD 234 E NP A IV P+E+VV+ + +V G + +PY IEPI L + S Sbjct: 179 GQIETNPQFAQIVPPSEMVVLVTLETKVGEEEGMMNFCIPYITIEPIISKLSSQFWFSSV 238 Query: 235 TQDTDMRWSQALRDEIMDVDVGIDATIVEHKVTLKQVLEFKAGDVIPVE---LPEYIILK 291 + + ++ LRD++ VD+ + A + +++++ +L + GD+I + + + +L Sbjct: 239 RRSSTTQYMGVLRDKLSTVDMDVVAEVGSLRLSVRDILGLRVGDIIRLHDTHVGDPFVLS 298 Query: 292 VEDLPTYRCKMGRTKENLALKICEQI 317 + + + C+ G + +A +I E+I Sbjct: 299 IGNRKKFLCQPGVVGKKIAAQILERI 324
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 114 bits (287), Expect = 4e-36 Identities = 56/119 (47%), Positives = 81/119 (68%) Query: 6 DDWASAMAEQAIDEAKAVEFDEFSNESAPLSEDEVSKLDAIMDIPVTISMEVGRSFINIR 65 D WA A+ EQ K+ F + +D IMDIPV +++E+GR+ + I+ Sbjct: 17 DLWADALNEQKATTTKSAADAVFQQLGGGDVSGAMQDIDLIMDIPVKLTVELGRTRMTIK 76 Query: 66 NLLQLNQGSVVELDRIAGEPLDVMVNGTLIAHGEVVVVNDKFGIRLTDVISQTERIKKL 124 LL+L QGSVV LD +AGEPLD+++NG LIA GEVVVV DK+G+R+TD+I+ +ER+++L Sbjct: 77 ELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGVRITDIITPSERMRRL 135
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 26.7 bits (59), Expect = 0.030 Identities = 23/110 (20%), Positives = 41/110 (37%), Gaps = 20/110 (18%) Query: 21 EIYKELNTCRDFGLKDQMTRAAVSIASNIAEGEERES------RAESARFLYFAKGSSGE 74 ++Y RDF D + A + + I + + + A A + + G+S Sbjct: 206 DVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSP 265 Query: 75 LATQIYIAIEIGVIEKKAGLNLIKEAREISAMLGALIKIRKGCVRETSAD 124 + YI +E G+ K ++ ++ G V ETSAD Sbjct: 266 VELMDYIQA----LEDALGIEAKKN----------MLPLQPGDVLETSAD 301
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 175 bits (446), Expect = 5e-54 Identities = 82/374 (21%), Positives = 144/374 (38%), Gaps = 66/374 (17%) Query: 1 MKILVTGGAGFIGSAVVRHIINNTQDSVINVDKLT--YAGNL-ESLASIESNERYVFEQV 57 MK LVTG AGFIG V + ++ V+ +D L Y +L ++ + + + F ++ Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAG-HQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKI 59 Query: 58 DICDRAELDRVFVKCKPDAVMHLAAESHVDRSITGPADFIQTNIVGTYTLLEATRAYWNT 117 D+ DR + +F + V V S+ P + +N+ G +LE R Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHN--- 116 Query: 118 LAEDAKKAFRFHHISTDEVYGDLPHPDDIEDETEPSTGKEPSADNEPSANKSLPLFTETT 177 K + S+ VYG N+ +P T+ + Sbjct: 117 ------KIQHLLYASSSSVYG---------------------------LNRKMPFSTDDS 143 Query: 178 SYEPSSPYSASKASSDHLVRAWLRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEGK 237 P S Y+A+K +++ + + YGLP YGP+ P+ + LEGK Sbjct: 144 VDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFFTVYGPWGRPDMALFKFTKAMLEGK 203 Query: 238 PLPIYGKGDQIRDWLYVEDHARALYKVV------------------TEGVVGETYNIGGH 279 + +Y G RD+ Y++D A A+ ++ YNIG Sbjct: 204 SIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNS 263 Query: 280 NEKQNLEVVQTICAILDSLVPKETKYKEQITYVTDRPGHDRRYAIDSSKMQRELGWTPIE 339 + + ++ +Q + L K + +PG + D+ + +G+TP Sbjct: 264 SPVELMDYIQALEDALGIEAKKN--------MLPLQPGDVLETSADTKALYEVIGFTPET 315 Query: 340 TFETGLKKTIEWYL 353 T + G+K + WY Sbjct: 316 TVKDGVKNFVNWYR 329
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 51.3 bits (123), Expect = 1e-09 Identities = 50/244 (20%), Positives = 89/244 (36%), Gaps = 43/244 (17%) Query: 1 MRVLITGCNGQVGCSLTEQLAKDTNTTVLALD--RDY----------------------L 36 M+ L+TG G +G ++++L + + V+ +D DY + Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGH-QVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKI 59 Query: 37 DITNLDAVHAAVVEFKPSIIINAAAHTAVDKAEEEVELSYAINRDGPKYLAQAAQDVG-A 95 D+ + + + + + AV + E N G + + + Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ 119 Query: 96 AILHISTDYVFEGNKVGEYVESD-TTNPQGVYGESKLAGEVAVAQACDKHI------ILR 148 +L+ S+ V+ N+ + D +P +Y +K A E+ H+ LR Sbjct: 120 HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTY--SHLYGLPATGLR 177 Query: 149 TAWVFGENGN------NFVKTMLRLGTTRDALNVVGDQFGGPTYAGDIANALIQIANRIT 202 V+G G F K ML G + D N G TY DIA A+I++ + I Sbjct: 178 FFTVYGPWGRPDMALFKFTKAMLE-GKSIDVYN-YGKMKRDFTYIDDIAEAIIRLQDVIP 235 Query: 203 QGDA 206 D Sbjct: 236 HADT 239
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 561 bits (1447), Expect = 0.0 Identities = 225/333 (67%), Positives = 270/333 (81%), Gaps = 1/333 (0%) Query: 1 MKYLVTGAAGFIGSKVSERLCAAGHEVVGIDNINDYYDVNLKLDRLKNLQSQTLFSFKKL 60 MKYLVTGAAGFIG VS+RL AGH+VVGIDN+NDYYDV+LK RL+ L F F K+ Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQP-GFQFHKI 59 Query: 61 DLADREGIATLFAEEGFDRVIHLAAQAGVRYSIDNPMAYADSNLVGHLTILEGCRHHKIQ 120 DLADREG+ LFA F+RV + VRYS++NP AYADSNL G L ILEGCRH+KIQ Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ 119 Query: 121 HLVYASSSSVYGLNSKMPFSTDDSVDHPISLYAATKKANELMSHTYSHLYGVPTTGLRFF 180 HL+YASSSSVYGLN KMPFSTDDSVDHP+SLYAATKKANELM+HTYSHLYG+P TGLRFF Sbjct: 120 HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFF 179 Query: 181 TVYGPWSRPDMALLKFTNKIVKGEAIDVYNHGNLSRDFTYIDDIVEGIIRIQDSVPVANP 240 TVYGPW RPDMAL KFT +++G++IDVYN+G + RDFTYIDDI E IIR+QD +P A+ Sbjct: 180 TVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHADT 239 Query: 241 EWNAAEATPATSSAPYRVFNIGNGSPVKLMDYISALEKSLGIEAIKNMMDMQPGDVHSTW 300 +W TPA S APYRV+NIGN SPV+LMDYI ALE +LGIEA KNM+ +QPGDV T Sbjct: 240 QWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQPGDVLETS 299 Query: 301 ADTEDLFKTVGYKPQTSVEEGVQKFVEWYKEYY 333 ADT+ L++ +G+ P+T+V++GV+ FV WY+++Y Sbjct: 300 ADTKALYEVIGFTPETTVKDGVKNFVNWYRDFY 332
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 43.3 bits (102), Expect = 4e-08 Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 5/55 (9%) Query: 8 GTFDLFHYGHVRLFKRLKALGDKLIVAVSTDEFNALKGKAAFFSYFQRAEIVEAC 62 G+FD +GH+ + +R L D++ VAV + K FS +R E + Sbjct: 7 GSFDPITFGHLDIIERGCRLFDQVYVAVLRN-----PNKQPMFSVQERLEQIAKA 56
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 59.7 bits (144), Expect = 7e-11 Identities = 50/279 (17%), Positives = 97/279 (34%), Gaps = 27/279 (9%) Query: 578 PKTEPKKQDKDSRNQGRNNNRRNNN---RRNDPRRNRNDNRSDSRNDSRNDSEQSKDKRA 634 P+ E + Q D+ N NN + + N+ R D SE + + A Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETT-ETVA 1041 Query: 635 KSSRSDSSDTRLPTEDTNKRQPRNEKVRKDTKSEAP----TTEQPKQEAARERRQRRNMR 690 ++S+ +S +D + +N +V K+ KS T E + + + Q + Sbjct: 1042 ENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETK 1101 Query: 691 --------RKVRVNNEQQEELKAEVAATEAPVQAKPSNDDKPARPKRQPRKPKAKAETVD 742 K +V E+ +E +V + +P Q + + +P+ +P + + Sbjct: 1102 ETATVEKEEKAKVETEKTQE-VPKVTSQVSPKQEQS----ETVQPQAEPARENDPTVNIK 1156 Query: 743 VEAVEQIETAGSVESAVQAPEAPKTAVETKVETETT--AIETAIEATEDAVATEDN---A 797 + TA + + A + + V T +E T N + Sbjct: 1157 EPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESS 1216 Query: 798 REPREGQRRSRRS-PRHLRAAGQRRRRDEDAQQNEDGSS 835 +P+ RRS RS P ++ A + S+ Sbjct: 1217 NKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTST 1255
>PF07675#Cleaved Adhesin Length = 1358 Score = 34.3 bits (78), Expect = 7e-04 Identities = 36/137 (26%), Positives = 51/137 (37%), Gaps = 16/137 (11%) Query: 119 SENLHIDFPIYRNNNGTL--ELAVGKANSNQ--DNREWAISDPKGLRSWIKDSSTYGNSA 174 +EN + D I R+N + ++ G+ + Q N K W S+ + Sbjct: 304 TENGNYDVVITRSNYLPVIKQIQAGEPSPYQPVSNLTATAQGQKVTLKWDAPSAKKAEGS 363 Query: 175 ELKQQQFNRLVRYVKRWRDHKFTDDSVRSKVYSIGLTVMLKADFVWALDDDGYPDDLKAL 234 R VKR D F + V + V+L AD VW D+ GY L A Sbjct: 364 -----------REVKRIGDGLFVTIEPANDVRANEAKVVLAADNVWG-DNTGYQFLLDAD 411 Query: 235 RDTISSVISTNYFRFIG 251 +T SVI F G Sbjct: 412 HNTFGSVIPATGPLFTG 428
>PF05272#Virulence-associated E family protein Length = 892 Score = 32.4 bits (73), Expect = 0.002 Identities = 11/44 (25%), Positives = 18/44 (40%) Query: 31 PIALVGPNGAGKTTLFSLLCGYITPTSGEVSLLGHKPGSPELLG 74 + L G G GK+TL + L G + + K ++ G Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIAG 641
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 79.1 bits (195), Expect = 1e-20 Identities = 31/111 (27%), Positives = 49/111 (44%), Gaps = 5/111 (4%) Query: 1 MKKARILVVDDDPVCSSLLLSILGD-DYQVTTVNTGCDVADIANIQRPDVIFLDIMMPGK 59 M A ILV DDD ++L L Y V + + D++ D++MP + Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 60 NGYQVLKDLKQ-DPQTSKLPVIIVSALSEQSDENLALRIGADGYITKPIVP 109 N + +L +K+ P LPV+++SA + A GA Y+ KP Sbjct: 61 NAFDLLPRIKKARPD---LPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDL 108
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 60.2 bits (146), Expect = 2e-11 Identities = 23/119 (19%), Positives = 51/119 (42%), Gaps = 7/119 (5%) Query: 698 VLVVEDNKVNQQVVSINLNKLNLPYLIANDGREALEHYKRHIGNFSVILMDCMMPVMDGF 757 +LV +D+ + V++ L++ I ++ G+ +++ D +MP + F Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAA--GDGDLVVTDVVMPDENAF 63 Query: 758 EATRAIREFEKEEDAKRVQIIALTASILDDDIQKCFDSGMDDYLPKPFKREVLVDKLAK 816 + I+ + + ++ ++A K + G DYLPKPF L+ + + Sbjct: 64 DLLPRIK-----KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 41.2 bits (96), Expect = 2e-05 Identities = 29/119 (24%), Positives = 45/119 (37%), Gaps = 17/119 (14%) Query: 493 YQFQMTSQASFSPPFNASYDYKIEF-------ILVSATDGLPIANAGEDQTARLGDTIIL 545 Y+ + N +Y Y + F + P A D + + + I Sbjct: 734 YKTVTAYFVNHKVDGNGNYVYDVVFHGMNTDTNTDVHVNKEPKAVIKSDSSVIVEEEINF 793 Query: 546 DGTSSFDDNTPTESLGYNWSFSSLPSGSTVSLTQANSANPSFVIDAFGEYTVELIVTDN 604 DGT S D++ ++ Y W F G +N A + + GEY V+L VTDN Sbjct: 794 DGTESKDEDGEIKA--YEWDFGD---GEK-----SNEAKATHKYNKTGEYEVKLTVTDN 842
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 140 bits (354), Expect = 3e-39 Identities = 74/214 (34%), Positives = 100/214 (46%), Gaps = 29/214 (13%) Query: 124 AGMKVCVIDSGLDRSNPDFEWSSITG----DNDIGTGNWDENGGPHGTHVAGTIGAADND 179 G+KV V+D+G D +PD + I G D+D G ++ HGTHVAGTI A +N+ Sbjct: 41 RGVKVAVLDTGCDADHPDLKARIIGGRNFTDDDEGDPEIFKDYNGHGTHVAGTIAATENE 100 Query: 180 IGVVGMAPGVEMHIIKVFNAQGWGYSSDLAHAANLCNAAGANIISMSLGGGGANSTEENA 239 GVVG+AP ++ IIKV N QG G + +IISMSLGG A Sbjct: 101 NGVVGVAPEADLLIIKVLNKQGSGQYDWIIQGIYYAIEQKVDIISMSLGGPEDVPELHEA 160 Query: 240 FKTFSSSGGLVVAAAGNDG-----NNVRSYPAGYTSVMMVGANDADNNIAAFSQFPACST 294 K +S LV+ AAGN+G + YP Y V+ VGA + D + + FS Sbjct: 161 VKKAVASQILVMCAAGNEGDGDDRTDELGYPGCYNEVISVGAINFDRHASEFSNS----- 215 Query: 295 FSTGRGKKNKTEIIDGSCVEITAGGVSTLSTYPQ 328 + V++ A G LST P Sbjct: 216 ---------------NNEVDLVAPGEDILSTVPG 234 Score = 48.3 bits (115), Expect = 4e-08 Identities = 18/72 (25%), Positives = 26/72 (36%), Gaps = 5/72 (6%) Query: 448 SDYGFMSGTSMATPAISGLAALLWSN-----HSGCTGNDIREALKASAYDAGESGRDNYF 502 Y SGTSMATP ++G AL+ T ++ L G S + Sbjct: 235 GKYATFSGTSMATPHVAGALALIKQLANASFERDLTEPELYAQLIKRTIPLGNSPKMEGN 294 Query: 503 GYGIAKAADASA 514 G A + + Sbjct: 295 GLLYLTAVEELS 306
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 62.9 bits (153), Expect = 9e-14 Identities = 22/122 (18%), Positives = 47/122 (38%), Gaps = 6/122 (4%) Query: 4 KITIILVDDHILVRAGIRSLLESIANVEVIKESGDGIEALSLLRTHQPTLLILDISLPGL 63 TI++ DD +R + L A +V + + L++ D+ +P Sbjct: 3 GATILVADDDAAIRTVLNQALS-RAGYDVRIT-SNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 64 NGLEVARSVTKMKTKTKILMLSMHSDVEYVAKALTIGSHGYLMK----ESAVEELETAIS 119 N ++ + K + +L++S + KA G++ YL K + + A++ Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 120 TL 121 Sbjct: 121 EP 122
>PF06580#Sensor histidine kinase Length = 349 Score = 39.5 bits (92), Expect = 6e-05 Identities = 41/304 (13%), Positives = 97/304 (31%), Gaps = 69/304 (22%) Query: 778 WSDPAKLNVKIVPPWWMKTSVRIASITIIIMMFIAFHKMRLARWQKHTARLQALQAQKQV 837 W A +N K V I ++ ++ M+ + A + + Sbjct: 99 WRLLAFINTKPVAFTLPLALSIIFNVVVVTFMWSLLYFGWHFFKNYKQAEIDQWKMASMA 158 Query: 838 ALDEVENREQQLST--AYQGLRSLASQIQNAKEEERKSISRELHDQFGQTLTATKINLQL 895 ++ + Q++ + L ++ + I + R+ ++ L + +L + Sbjct: 159 QEAQLMALKAQINPHFMFNALNNIRALILEDPTKAREMLTS-LSELMRYSLRYSNARQVS 217 Query: 896 YKKFNYQEQERIESAISITHTMIQQMR-----SISFNLRPALLDDEGLVAGVKLQLEKMS 950 E ++S + + ++ + PA++D +Q+ M Sbjct: 218 LA----DELTVVDSYLQL-----ASIQFEDRLQFENQINPAIMD---------VQVPPM- 258 Query: 951 ALIAKPIKLSVSRDFPMVNQGITINVFRIIQESVNNAIRHA-----NASQIIVSLSYHSE 1005 ++Q V N I+H +I++ + + Sbjct: 259 ----------------------------LVQTLVENGIKHGIAQLPQGGKILLKGTKDNG 290 Query: 1006 QLFIEIKDDGKGFDVDKVKENTFSGVHLGLLGMEERVHSLSGK---LLLHSSISNGSIIK 1062 + +E+++ G +NT GL + ER+ L G + L + + Sbjct: 291 TVTLEVENTGSLA-----LKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAM- 344 Query: 1063 VVIP 1066 V+IP Sbjct: 345 VLIP 348
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 29.0 bits (65), Expect = 0.029 Identities = 12/41 (29%), Positives = 23/41 (56%), Gaps = 2/41 (4%) Query: 248 SFPYLIMLAALLMPTCLRQNYLLFSWLITMVILLVVDLAML 288 P L+ ++ +++ CL Y SW I + ++LVV L ++ Sbjct: 871 QAPALVAISFVVVFLCLAALYE--SWSIPVSVMLVVPLGIV 909
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 136 bits (345), Expect = 7e-38 Identities = 82/427 (19%), Positives = 155/427 (36%), Gaps = 54/427 (12%) Query: 25 QPISIYVSATVLLVIIVAIVFFL--SLSHYARKETVRGYLVPDKGLIKTYANRSGNIDVL 82 P+S ++ ++ F+ L T G L + + + + Sbjct: 51 TPVSRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEI 110 Query: 83 HVSEGDIIKKGSPLATIV--------------LSRSMLSGEEL-SESLIDELKLQLTLLT 127 V EG+ ++KG L + L ++ L S EL L Sbjct: 111 IVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKL 170 Query: 128 TEQKVNQSLLAKETQRLKNSITDN-----KQALNVSVNLEALLTEKLALQVK-------- 174 ++ Q++ +E RL + I + Q +NL+ E+L + + Sbjct: 171 PDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLS 230 Query: 175 -----QQTQHQKLFDDGYLSTLDYQSQQQKLIAVRQEIENLKSNQVQIRSQLNDALSELD 229 + L ++ Q+ K + E+ KS QI S++ A E Sbjct: 231 RVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQ 290 Query: 230 ILPSQFVLKDGDIERRRSELKRQIDETENSY--------RFVIRAAEAGTVASIQI-VEG 280 ++ F +I + + I VIRA + V +++ EG Sbjct: 291 LVTQLF---KNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEG 347 Query: 281 EFIATNRPLMSLIPQGALLVAELLLPTRSAGFVKSGDEARLRFDAIPYQRFGFLESRVSR 340 + T LM ++P+ L L+ + GF+ G A ++ +A PY R+G+L +V Sbjct: 348 GVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKN 407 Query: 341 IDKALLLDGEAKVPVALSEPVYRIRTQLSKQDMLAYSDSFPLKSGMLLEADIVLDRRSLL 400 I+ + D V+ + + + + + + PL SGM + A+I RS++ Sbjct: 408 INLDAIEDQR-------LGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGMRSVI 460 Query: 401 DWLLDPI 407 +LL P+ Sbjct: 461 SYLLSPL 467
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 114 bits (287), Expect = 4e-37 Identities = 32/89 (35%), Positives = 56/89 (62%), Gaps = 1/89 (1%) Query: 2 TKSELIEKLATRQSQLSAKEVEAAIKEMLEQMADTLEAGDRIEIRGFGSFSLHYRAPRTG 61 K +LI K+A ++L+ K+ AA+ + ++ L G+++++ GFG+F + RA R G Sbjct: 3 NKQDLIAKVA-EATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKG 61 Query: 62 RNPKTGTSVELEGKYVPHFKPGKELRERV 90 RNP+TG ++++ VP FK GK L++ V Sbjct: 62 RNPQTGEEIKIKASKVPAFKAGKALKDAV 90
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 95.3 bits (237), Expect = 3e-25 Identities = 33/150 (22%), Positives = 69/150 (46%) Query: 2 TNLYLVDDDQAVLDSLTWMLNGLGYQPKGFLSADSFLQQVDINNTGIAILDVQMPGMDGS 61 + + DDD A+ L L+ GY + +A + + + + + + DV MP + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 ALLTHMSKAQSPIAVIMLSGHGSIAMAVQAIQKGALDFLEKPVDGDKLVRLLDQAGELTE 121 LL + KA+ + V+++S + A++A +KGA D+L KP D +L+ ++ +A + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 122 QNLRSKQERQALSDKLATLTPREHEVMEKV 151 + ++ L + E+ + Sbjct: 124 RRPSKLEDDSQDGMPLVGRSAAMQEIYRVL 153
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 66.4 bits (162), Expect = 2e-14 Identities = 61/350 (17%), Positives = 112/350 (32%), Gaps = 24/350 (6%) Query: 2 MKIVKLTLLVAAVLASPSVMADAY-KFYGRIDYSITHSDSGSATHSGKSGTVLENNWSRL 60 MK + L +AA+ + Y ++ S + + +G+ S ++GT + + S++ Sbjct: 1 MKKSLIALTLAALPVAAMADVTLYGTIKAGVETSRSVAHNGAQAASVETGTGIVDLGSKI 60 Query: 61 GIKGDAAINEDFTVFYQIEVGVNGATEGKQNNPFSARPTFLGIKHSTVGQLAAGRIDPVF 120 G KG + +Q+E + A R +F+G+K G+L GR++ V Sbjct: 61 GFKGQEDLGNGLKAIWQVEQKASIAGTDSGW---GNRQSFIGLK-GGFGKLRVGRLNSVL 116 Query: 121 KMAKGTADAMDMYSLKHDRLFAGDKRWGDSLEYKTVKWNKLQFGASYILEDNYYGEDDVR 180 K A + S+ Y + ++ L Y D+ Sbjct: 117 KDTGDINPWDSKSDYLGVNKIAEPEARLISVRYDSPEFAGLSGSV------QYALNDNAG 170 Query: 181 RDNGN-YQVALTYGDKLFKSGDLYLAAAYTDGVEDIKGFRAVAQYKIDKLMLGSIYQSSE 239 R N Y Y + F + E++ + + ++Y S Sbjct: 171 RHNSESYHAGFNYKNGGFFVQYGGAYKRHHQVQENVNIEKYQIHRLVSGYDNDALYASVA 230 Query: 240 IVNPNLDNWQQRDGDG--FIVSAKYQFDKLTLKAQYGQDDSGTGKIAGRVYDKLGAAATE 297 + + ++ V+A + + + G Y+ Sbjct: 231 VQQQDAKLVEENYSHNSQTEVAATLAYRFGNVTPRVSYAHGFKGSFDATNYNND------ 284 Query: 298 VPEVSQWAIGAEYRLSKSTRVHTELGQFDVKQYSD-FDDTIMSVGFRLDF 346 Q +GAEY SK T G + F T VG R F Sbjct: 285 ---YDQVVVGAEYDFSKRTSALVSAGWLQEGKGESKFVSTAGGVGLRHKF 331
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 28.7 bits (64), Expect = 0.025 Identities = 8/34 (23%), Positives = 15/34 (44%) Query: 154 SSLDDDAPLLSTNEQAVDRSVSVTRVEFIPQTGR 187 ++L D+ L + V ++ R EF + G Sbjct: 763 NTLADNVDLDNAVANVVPTRGAIVRAEFKARVGI 796
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.018 Identities = 10/52 (19%), Positives = 20/52 (38%), Gaps = 5/52 (9%) Query: 199 LRDKAILQLGLQGGFRRSELAEIRVEHISFL-REKLKVRVPYSKSNQQGQRE 249 + +L FRR++ ++ +F K + R Y + Q R+ Sbjct: 639 IAGIVAYELSEMTAFRRADAEAVK----AFFSSRKDRYRGAYGRYVQDHPRQ 686
>NEISSPPORIN#Neisseria sp. porin signature. Length = 348 Score = 26.5 bits (58), Expect = 0.035 Identities = 19/71 (26%), Positives = 33/71 (46%), Gaps = 16/71 (22%) Query: 1 MRRYLLSLGLLLLPVSAMANIIVD---KTGVDEKDYVYDLHQCTEMSTQVKQKQTEGSAI 57 M++ L++L L LPV+AMA++ + K GV + V+ + S + Sbjct: 1 MKKSLIALTLAALPVAAMADVTLYGAIKAGV-------------QTYRSVEHTDGKVSKV 47 Query: 58 GTAAKGAAIGS 68 T ++ A GS Sbjct: 48 ETGSEIADFGS 58
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 73.2 bits (179), Expect = 9e-18 Identities = 47/195 (24%), Positives = 80/195 (41%), Gaps = 16/195 (8%) Query: 2 KHVVITGANRGIGLAFVGHYLTTGWQVTA--CCRNLNDAVALQHQQSKFTALKLVELDVT 59 K ITGA +GIG A + G + A + V + A DV Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAF-PADVR 67 Query: 60 IPSSIAELKRSLGSEA--IDLLINNAGYYGPKGVRFGTTD---INQWQAVLAVNTIAPLI 114 ++I E+ + E ID+L+N AG +R G +W+A +VN+ Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGV-----LRPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 115 LTETLYPNLKIAQNCVLAFISSKVGSMQDNSSGGGYYYRSSKAALNSVVKSLSIDLIQDG 174 + ++ + ++ + + S + S Y SSKAA K L ++L + Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAA---YASSKAAAVMFTKCLGLELAEYN 179 Query: 175 IKCVVLHPGWVQTEM 189 I+C ++ PG +T+M Sbjct: 180 IRCNIVSPGSTETDM 194
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 137 bits (346), Expect = 1e-41 Identities = 78/249 (31%), Positives = 121/249 (48%), Gaps = 12/249 (4%) Query: 6 KVIFVTGAGQGMGLAMVKLFAEQGAKVAAIDINEAAAKQVAEQQSAESGSEVIGIGCDIS 65 K+ F+TGA QG+G A+ + A QGA +AA+D N ++V AE D+ Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAE-ARHAEAFPADVR 67 Query: 66 QSSSVRDAIAEVVQRLGSVDVVINNAGIGSIDSFIDTPDENWHKVINVNLTGTFYCCREA 125 S+++ + A + + +G +D+++N AG+ DE W +VN TG F R Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 126 ARVMKEQGSGCIINISSTAVMSGD-GPSHYCASKAGVIGLTRSIAKELAASGIRVNTIVP 184 ++ M ++ SG I+ + S + Y +SKA + T+ + ELA IR N + P Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 185 GPTNTPMMADI--PEEWTQQMIN--------AIPLGRMGEPEDIAKLASFIASEDASFIT 234 G T T M + E +Q+I IPL ++ +P DIA F+ S A IT Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHIT 247 Query: 235 GQNLAVNGG 243 NL V+GG Sbjct: 248 MHNLCVDGG 256
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 67.4 bits (164), Expect = 3e-15 Identities = 61/259 (23%), Positives = 99/259 (38%), Gaps = 19/259 (7%) Query: 2 KACNSRTVIITGSGGGLGRAYALALAAEGANVVVNDIRAGAAAAVVDEILTQGGQAIANS 61 K + ITG+ G+G A A LA++GA++ D VV + + A A Sbjct: 4 KGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP 63 Query: 62 DDITRMDTATNIVDAALEAFGEVHVLINNAGVLADRMFISLSEADWDKVMQVHLKGHFCL 121 D+ I G + +L+N AGVL + SLS+ +W+ V+ G F Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 122 ANILGRRWRDLAKAGQPVDARIINTSSGAGLQGSIGQSNYSAAKGGIASLTLVQAAELGR 181 + + + D I+ S + Y+++K T EL Sbjct: 124 SRSVSKYMMDRRSGS------IVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAE 177 Query: 182 YGVTVNALAPAA-RTSMTQSAMPD-----VVKKPEDGSFDLW-------APENVAPLVVW 228 Y + N ++P + T M S D V K +F P ++A V++ Sbjct: 178 YNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLF 237 Query: 229 LSSSESKHISGQILESQGG 247 L S ++ HI+ L GG Sbjct: 238 LVSGQAGHITMHNLCVDGG 256
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 92.0 bits (228), Expect = 2e-24 Identities = 66/245 (26%), Positives = 114/245 (46%), Gaps = 13/245 (5%) Query: 14 LKGKSVLITAAAGAGIGFAAARRAAEEGCRALMISDIHPRRLDEAVTRLRVETGLEHIYG 73 ++GK IT AA GIG A AR A +G + D +P +L++ V+ L+ E + Sbjct: 6 IEGKIAFITGAA-QGIGEAVARTLASQGAH-IAAVDYNPEKLEKVVSSLKAEARHAEAFP 63 Query: 74 QLCNVTDQQDVTTLIEQAELKLAGVDVLINNAGLGGQKNVVDMTDKEWSTVLDITLTGTF 133 +V D + + + E ++ +D+L+N AG+ + ++D+EW + TG F Sbjct: 64 --ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVF 121 Query: 134 RMIREILPHMQARGSGVIVNNASVLGWRAQKEQAHYAAAKAGVMALTRCSALEAAEHGVR 193 R + +M R SG IV S + A YA++KA + T+C LE AE+ +R Sbjct: 122 NASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIR 181 Query: 194 INAVSPSIALHDFLKKASSEE---------LLNQLASKEAFGRAAEVWEVANVMMFLASD 244 N VSP D ++E L + + A+ ++A+ ++FL S Sbjct: 182 CNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSG 241 Query: 245 YSSYM 249 + ++ Sbjct: 242 QAGHI 246
>TYPE3OMBPROT#Type III secretion system outer membrane B protein family signature. Length = 538 Score = 27.0 bits (59), Expect = 0.026 Identities = 11/36 (30%), Positives = 19/36 (52%), Gaps = 4/36 (11%) Query: 66 HVDVRNQDIIVANYNGSFVC----KIIDKVNRLLLS 97 H+ + N++I V YNG +C + D + + LS Sbjct: 174 HMKIGNKNIFVKEYNGKGICCASTRESDHIANMWLS 209
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 30.8 bits (69), Expect = 0.024 Identities = 16/86 (18%), Positives = 35/86 (40%), Gaps = 13/86 (15%) Query: 409 VKNRRKREDQFYTLKQIDDFLKQTITKS----KELSADMIYRVRDSSNDYSYDVEYEKLL 464 +++ + D +++D LK+ KS K ++A + D + +Y YDV + + Sbjct: 703 GRSQGEENDWKDMNSKLNDILKELSKKSWNGYKTVTAYFVNHKVDGNGNYVYDVVFHGMN 762 Query: 465 FIT---------PVGSTALNYSGMIK 481 T P + S +++ Sbjct: 763 TDTNTDVHVNKEPKAVIKSDSSVIVE 788
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 32.2 bits (73), Expect = 0.002 Identities = 16/106 (15%), Positives = 36/106 (33%), Gaps = 4/106 (3%) Query: 206 ILELQPHSSILITNLGYSYYLTAELTMAEKYLRQAIREDSSFNRAWTNLGLVYVRKGFYK 265 + E+ + + +L ++ Y + + A K + D +R + LG G Y Sbjct: 28 LNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYD 87 Query: 266 RAL----AAFEQTMSPADALNDLGYFLMLEGQYEKAIGLFERAIDM 307 A+ + L+ +G+ +A A ++ Sbjct: 88 LAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQEL 133
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.046 Identities = 11/59 (18%), Positives = 27/59 (45%) Query: 170 ALDGPSLSIRRFAVDKLNARQLIDIGSVTESMIELLKGSVKGKLNILVSGGTGSGKTTL 228 AL P + D + L+ + + + +L ++ L ++++G +G+GK + Sbjct: 118 ALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELV 176
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 146 bits (370), Expect = 5e-40 Identities = 58/256 (22%), Positives = 112/256 (43%), Gaps = 23/256 (8%) Query: 176 QVMLEVVVAEVQRNVARQFDSKFLI--------FNQGSNLSGGVIGGGGGFDPGSIGG-- 225 QV++E ++AEVQ ++ N G +S + G G++ Sbjct: 346 QVLVEAIIAEVQDADGLNLGIQWANKNAGMTQFTNSGLPISTAIAGANQYNKDGTVSSSL 405 Query: 226 VDGKGLFAQYINGDLMMNFALDVA--KQNGLAKVLAEPNVTAMSGQSAEFLSGGEFPIPV 283 F G N+A+ + + +LA P++ + A F G E P+ Sbjct: 406 ASALSSFNGIAAGFYQGNWAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVPVLT 465 Query: 284 P-----GENGNTTIEYRDYGVGVKFVPTVLDSGQINLNLNVVVSEISTANGFSISGNTST 338 G+N T+E + G+ +K P + + + L + VS ++ A +++ Sbjct: 466 GSQTTSGDNIFNTVERKTVGIKLKVKPQINEGDSVLLEIEQEVSSVADAAS------STS 519 Query: 339 SLVVPSLVKRSTATTVELADGQTIAISGLISDTLRENIDKLPGLGDVPVLGQLFTSKSFQ 398 S + + R+ V + G+T+ + GL+ ++ + DK+P LGD+PV+G LF S S + Sbjct: 520 SDLGATFNTRTVNNAVLVGSGETVVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKK 579 Query: 399 SGQSELVILVTPRLVR 414 + L++ + P ++R Sbjct: 580 VSKRNLMLFIRPTVIR 595
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.2 bits (68), Expect = 0.019 Identities = 9/34 (26%), Positives = 17/34 (50%) Query: 159 KDLLFKIGPAMNSSRPVLIYGPPGTGKSYLCRHL 192 +++ + M + ++I G GTGK + R L Sbjct: 147 QEIYRVLARLMQTDLTLMITGESGTGKELVARAL 180
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 33.2 bits (76), Expect = 3e-04 Identities = 37/184 (20%), Positives = 69/184 (37%), Gaps = 39/184 (21%) Query: 7 LLQVVIAGVFFILAIVVDLTREKIPNWLCLFAIFCGFLVN---GYFAHLSGLMISFIGFS 63 L ++ + +DL + +P+ L L ++ G L N G+ + ++ + G+ Sbjct: 134 TLAALLLTWVLVALTFIDLDKMLLPDQLTLPLLWGGLLFNLLGGFVSLGDAVIGAMAGYL 193 Query: 64 LAFIILFPTFIFKI------LGAGDIKLMMGIGALMGPQLLAWSIAYGIIAGAVTSILLI 117 + + + + FK+ +G GD KL+ +GA +G Q L + + GA I LI Sbjct: 194 VLWSL---YWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALPIVLLLSSLVGAFMGIGLI 250 Query: 118 IWKSGFSGCIKTFKRYWDCFYLRTYFKPEEGEAAGQRVPYAPALAIGWVWACSLNQDITH 177 + + + +P+ P LAI A IT Sbjct: 251 LLR---------------------------NHHQSKPIPFGPYLAIAGWIALLWGDSITR 283 Query: 178 LYTS 181 Y + Sbjct: 284 WYLT 287
>PF07201#Hypersensitivity response secretion protein HrpJ Length = 293 Score = 30.6 bits (69), Expect = 0.011 Identities = 17/93 (18%), Positives = 30/93 (32%), Gaps = 14/93 (15%) Query: 122 EYLELLFEDLELPN--------LQNNRLNKLVEYQVYRAGFTNDGVPANINIVRSLRSSL 173 +YL +LE L N+ L + + Y G + + ++ LR +L Sbjct: 89 QYLSK-VPELEQKQNVSELLSLLSNSPNISLSQLKAYLEGKSEEPSEQFK-MLCGLRDAL 146 Query: 174 ARRTAMTSTKRSKLKALEQELNQLENTPGSEAE 206 R + +EQ L + G Sbjct: 147 KGRPELAHL----SHLVEQALVSMAEEQGETIV 175
>PF08280#M protein trans-acting positive regulator Length = 530 Score = 28.3 bits (63), Expect = 0.046 Identities = 20/96 (20%), Positives = 40/96 (41%), Gaps = 15/96 (15%) Query: 219 KSLLPFVGDEHKDMPKGLMFNAKEYL----QLVDDTGRIQRNDKRGAISQSSQQLLYRLN 274 +LLP + ++ + K LMF +K +L + +T +G +Q+L L Sbjct: 333 ITLLPNLKEQKASLVKALMFFSKSFLFNLQHFIPETNLFVSPYYKG-----NQKLYTSLK 387 Query: 275 IPAENWLKMTAEFTKIFKGAVGNTQELSTYCEHLER 310 + E W+ K+ N + +C ++E+ Sbjct: 388 LIVEEWM------AKLPGKRYLNHKHFHLFCHYVEQ 417
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 57.5 bits (139), Expect = 3e-11 Identities = 76/387 (19%), Positives = 134/387 (34%), Gaps = 26/387 (6%) Query: 2 NPKVYLLALITFATGMDENIAGGIVPFIAEDLGVSISAA---GQLTTVFSLTFALAAPVL 58 N + ++ + + ++P + DL S G L +++L APVL Sbjct: 4 NRPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVL 63 Query: 59 LFATAKFNRLRLLQVALFTFCLGNLFSALSPSYAFLFGMRIISAASCALIVVLVTTIATE 118 + +F R +L V+L + A +P L+ RI++ + A V IA + Sbjct: 64 GALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIA-D 122 Query: 119 MVEAEFKGRAIGIIFMGISGSLVLGVPVGLLFCNWLGWRAPFAFIALMALLLCIIVPLML 178 + + + + R G + +V G +G APF A + L + +L Sbjct: 123 ITDGDERARHFGFMSACFGFGMVAGPVLG-GLMGGFSPHAPFFAAAALNGLNFLTGCFLL 181 Query: 179 PNVSSNGQRIPLS----------KYAEHLKNPKLLTAQLVSILMIGGHFVLFAYLAPYLQ 228 P S G+R PL ++A + L A + ++G A + + Sbjct: 182 PE-SHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPA--ALWVIFGE 238 Query: 229 ATIGASKSELTFYYFLFGAA-AITGGYMGGWLSDKLGHITAII--LIPSIFILFLGAIPF 285 + + FG ++ + G ++ +LG A++ +I L A Sbjct: 239 DRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLA--- 295 Query: 286 TLNSLVLFIPCMMLWGGLSWTISPIVQNYL-IQSDHANAGVSIAVNNTSMHLGVALGSLL 344 + P M+L P +Q L Q D G L +G LL Sbjct: 296 FATRGWMAFPIMVLLASGG-IGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLL 354 Query: 345 GGVVIKYSSVNWTPAIGVFVVVLSLLC 371 + S W + L LLC Sbjct: 355 FTAIYAASITTWNGWAWIAGAALYLLC 381
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.7 bits (72), Expect = 0.003 Identities = 34/131 (25%), Positives = 50/131 (38%), Gaps = 17/131 (12%) Query: 34 DGHLLVEGPPGLAKT---RAVKALCDGVEGDFHRIQ---FTPDLLPADLTG------TDI 81 D L++ G G K RA+ G F I DL+ ++L G T Sbjct: 160 DLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGA 219 Query: 82 YRAQTATFEFEAGPIFHNLILADEINRAPAKVQSALLEAMAEGQVT-VGKHSYQLPELFL 140 T FE G + DEI P Q+ LL + +G+ T VG + ++ + Sbjct: 220 QTRSTGRFEQAEG----GTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRI 275 Query: 141 VMATQNPLENE 151 V AT L+ Sbjct: 276 VAATNKDLKQS 286
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 47.1 bits (112), Expect = 6e-08 Identities = 25/155 (16%), Positives = 48/155 (30%), Gaps = 44/155 (28%) Query: 79 AALLEITNKEQGAQLAAAEADYAKASALNTEAQLQLERYQKLFPKGAISK---------- 128 E+ ++ A+ A + L+ + +L+ + L K AI+K Sbjct: 202 KYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKY 261 Query: 129 ----GEMDEAEANAKSTKQAVSVAKARITQATES-------------------------- 158 E+ ++ + + + AK T+ Sbjct: 262 VEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKN 321 Query: 159 ---LKYTVVSAPFSGVVTQRHV-EQGETVTPGQPL 189 + +V+ AP S V Q V +G VT + L Sbjct: 322 EERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETL 356 Score = 30.2 bits (68), Expect = 0.012 Identities = 16/82 (19%), Positives = 30/82 (36%), Gaps = 5/82 (6%) Query: 163 VVSAPFSGVVTQRHVEQGETVTPGQPLYSGYSLKQMRAVTQVPQRYIQAL-----KQQPK 217 + + +V + V++GE+V G L +L + +QA Q Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILS 157 Query: 218 FKLTLNNGQQLDVSNPTLFSFV 239 + LN +L + + F V Sbjct: 158 RSIELNKLPELKLPDEPYFQNV 179
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 505 bits (1301), Expect = e-164 Identities = 227/1066 (21%), Positives = 438/1066 (41%), Gaps = 72/1066 (6%) Query: 25 LLALLGLLFGLFAVLVTPKEEEPQIDVTFADVFVPFPGATPREVESLVTLPTEQIISEIK 84 +LA++ ++ G A+L P + P I V +PGA + V+ VT EQ ++ I Sbjct: 14 VLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQVIEQNMNGID 73 Query: 85 GIDTLYSFSQPDGALFIVV-FEVGIERNDAIVKLYNQIYSNLDKLPLAAGVGEPQIKPRG 143 + + S S G++ I + F+ G + + A V++ N++ LP V + I Sbjct: 74 NLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLP--QEVQQQGISVEK 131 Query: 144 IDDVPIVSLTLWSKQPQVSAEQLTHIAN-GLETEIKRIPGTREISSVGEHQLILNVRIDP 202 ++ S P + + ++ ++ + R+ G ++ G Q + + +D Sbjct: 132 SSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA-QYAMRIWLDA 190 Query: 203 LKLNYYGISFDEINQSLSSNN------HISMPASLVQGNQEIKVQAGQFLQNIEDVKQLV 256 LN Y ++ ++ L N + +L + A +N E+ ++ Sbjct: 191 DLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKNPEEFGKVT 250 Query: 257 VAVKQDASGQASPVYLADLAQISLKSDIPVKSAWHGDKQEIYPAVTIAIGKQPGKNAVDV 316 + V D S V L D+A++ L + A K PA + I G NA+D Sbjct: 251 LRVNSDGS----VVRLKDVARVELGGENYNVIARINGK----PAAGLGIKLATGANALDT 302 Query: 317 ANAILERVNQVENVLIPDGVEVSISRNYGETAGDKANTLMLKLVFATAAVVILVLITMG- 375 A AI ++ +++ P G++V + + ++ L A V +++ + + Sbjct: 303 AKAIKAKLAELQPFF-PQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQN 361 Query: 376 FREAIVVGIAIIITLALTLFASWAWGFTLNRISLFALIFSIGILVDDAIVVVENIHRHMA 435 R ++ IA+ + L T A+G+++N +++F ++ +IG+LVDDAIVVVEN+ R M Sbjct: 362 MRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 436 MGKRSFSELIPIAVDEVGGPTILATFTVIAALLPMAFVSGLMGPYMSPIPINASMGMLIS 495 K E ++ ++ G + + A +PMAF G G I M +S Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 496 LGVAFMITPWLSRKFLKYPQTPHNEKQHSEQHLNQGIMFKLFNHLIGPFVQGKNARKARL 555 + VA ++TP L LK P + + H + G F+H + + Sbjct: 482 VLVALILTPALCATLLK----PVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGST 537 Query: 556 GLAAGIFILIAGAIALPMAKLVVLKMLPFDNKSEFQVMVDLPEGTPVEQTQKALKELGRY 615 G I+ LI + + + + LP +++ F M+ LP G E+TQK L ++ Y Sbjct: 538 GRYLLIYALIVAGMVV-LFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDY 596 Query: 616 LNQVEEVESYQLYAGTSAPMNFNGLVRHYFLRQTQELGDIQVNLVDKKHRDRDSHSIALS 675 + E+ ++ T +F+G Q Q G V+L + R+ D +S Sbjct: 597 YLKNEKANVESVF--TVNGFSFSG--------QAQNAGMAFVSLKPWEERNGDENSAEAV 646 Query: 676 VREPLQAIGEKYNANIKVVEVPPGPPVWSPILAEVYGPS-EAIREQAANALLDVLKQ--- 731 + +G+ + V P + A + +AL Q Sbjct: 647 IHRAKMELGKIRDGF---VIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLG 703 Query: 732 -----TKDVVDIDIYLPESAAKWQVIIDRSKASLLGVPYSKIVDLVATAVGGKDISYLYK 786 +V + E A++++ +D+ KA LGV S I ++TA+GG ++ Sbjct: 704 MAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFID 763 Query: 787 ANQKHPVPINIQLQEGAKVDLDQVLNLTLRGNNNQAVALSELVRIDKGNIDAPIIHKNMI 846 + + +Q ++ + V L +R N + V S + N + Sbjct: 764 --RGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGL 821 Query: 847 PMIMVVADMAGPLDSPLYGMFDMVGKINDKQGLGFDQHYISQPNGLDSVAILWDGEWKIT 906 P + + + A P D + + + P G + W G Sbjct: 822 PSMEIQGEAA-----PGTSSGDAMALMENLAS--------KLPAG---IGYDWTGMSYQE 865 Query: 907 YETFRDMGIAYAVGMIAIYLLVVAQFRSYIVPLIIMAPIPLTIIGVMPGHALLGAQFTAT 966 + A+ + ++L + A + S+ +P+ +M +PL I+GV+ L + Sbjct: 866 RLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVY 925 Query: 967 SMIGMIALAGIIVRNSILLVDFIVQETAA-GVPFEQAVIHSGAVRAKPIMLTALAAMIGA 1025 M+G++ G+ +N+IL+V+F G +A + + +R +PI++T+LA ++G Sbjct: 926 FMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGV 985 Query: 1026 LFIIDDP-----IFNGLAISLIFGILISTLLTLVVIPVLYYAVMKK 1066 L + N + I ++ G++ +TLL + +PV + + + Sbjct: 986 LPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRRC 1031 Score = 90.3 bits (224), Expect = 2e-20 Identities = 82/518 (15%), Positives = 184/518 (35%), Gaps = 41/518 (7%) Query: 8 GISGRIASAFQSSAITPLLALLGLLFGLFAVLVTPKEEEPQIDVTFADVFVPFPGATPRE 67 + + S+ L+ L + + L P P+ D + P +E Sbjct: 525 HYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQE 584 Query: 68 VESLVTLPTEQII--SEIKGIDTLYSF--------SQPDGALFIVV--FEVGIERNDAIV 115 V +E ++++++ +Q G F+ + +E ++ Sbjct: 585 RTQKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAE 644 Query: 116 KLYNQIYSNLDKLPLAAGVGEPQIKPRGIDDVPIVSLTLWSKQPQVSAEQLTHIANGLET 175 + ++ L K+ + + L Q + + LT N L Sbjct: 645 AVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFEL-IDQAGLGHDALTQARNQLLG 703 Query: 176 EIKRIPGT--REISSVGEHQLILNVRIDPLKLNYYGISFDEINQSLSSNNHISMPASLVQ 233 + P + + E + +D K G+S +INQ++S+ + + Sbjct: 704 MAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFID 763 Query: 234 GNQEIKV---QAGQFLQNIEDVKQLVVAVKQDASGQASPVYLADLAQISLKSDIPVKSAW 290 + K+ +F EDV +L V A+G+ P + P + Sbjct: 764 RGRVKKLYVQADAKFRMLPEDVDKLYVR---SANGEMVP--FSAFTTSHWVYGSPRLERY 818 Query: 291 HGDKQEIYPAVTIAIGKQPGKNAVDVANAILERVNQVENVLIPDGVEVSISRNYGETAGD 350 +G P++ I PG ++ D + ++ +P G+ + G + + Sbjct: 819 NG-----LPSMEIQGEAAPGTSSGDAMALMENLASK-----LPAGIGYDWT---GMSYQE 865 Query: 351 KANTLMLKLVFATAAVVILVLITMGFREAIVVGIAIIITLALT----LFASWAWGFTLNR 406 + + + A + VV+ + + + E+ + +++++ + L L A+ + + Sbjct: 866 RLSGNQAPALVAISFVVVFLCLAALY-ESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDV 924 Query: 407 ISLFALIFSIGILVDDAIVVVENIHRHMAMGKRSFSELIPIAVDEVGGPTILATFTVIAA 466 + L+ +IG+ +AI++VE M + E +AV P ++ + I Sbjct: 925 YFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILG 984 Query: 467 LLPMAFVSGLMGPYMSPIPINASMGMLISLGVAFMITP 504 +LP+A +G + + I GM+ + +A P Sbjct: 985 VLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVP 1022 Score = 61.8 bits (150), Expect = 1e-11 Identities = 33/166 (19%), Positives = 78/166 (46%), Gaps = 10/166 (6%) Query: 908 ETFRDMGIAYAVGMIAIYLLVVAQFRSYIVPLIIMAPIPLTIIGVMPGHALLGAQFTATS 967 E + + A + + +YL + R+ ++P I +P+ ++G A G + Sbjct: 339 EVVKTLFEAIMLVFLVMYL-FLQNMRATLIPTIA---VPVVLLGTFAILAAFGYSINTLT 394 Query: 968 MIGMIALAGIIVRNSILLVDFIVQE-TAAGVPFEQAVIHS-----GAVRAKPIMLTALAA 1021 M GM+ G++V ++I++V+ + + +P ++A S GA+ ++L+A+ Sbjct: 395 MFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFI 454 Query: 1022 MIGALFIIDDPIFNGLAISLIFGILISTLLTLVVIPVLYYAVMKKR 1067 + I+ +I+++ + +S L+ L++ P L ++K Sbjct: 455 PMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPV 500
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 91.2 bits (226), Expect = 2e-23 Identities = 39/214 (18%), Positives = 93/214 (43%), Gaps = 15/214 (7%) Query: 4 WTNFTDLLIQTIGFLTTEVGVSQGVAIILLTLVVRLLFSPISCSAMINSYKNKKTMAAIK 63 + L + + ++ + VG + G +II++T +VR + P++ Y + M ++ Sbjct: 333 LWFISQPLFKLLKWIHSFVG-NWGFSIIIITFIVRGIMYPLT----KAQYTSMAKMRMLQ 387 Query: 64 PELDKLKSVYKDKPNEMAKQTMALYRKHDIKFISKTLVANVSSQAIFGFGMFQVLQKAIF 123 P++ ++ D ++++ MALY+ + + + Q ++ +L ++ Sbjct: 388 PKIQAMRERLGDDKQRISQEMMALYKAEKVNPLGGCF--PLLIQMPIFLALYYMLMGSVE 445 Query: 124 ---SSKFAWISNIAKPD--IALAMLVGALTYLSMLMMPDSAE--QANALFLLIPAMVSVA 176 + WI +++ D L +L+G + M P + + +P + +V Sbjct: 446 LRQAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTV- 504 Query: 177 VLVTAPSALSLYWATSSAFGALQSLVVNKYCEKQ 210 + PS L LY+ S+ +Q ++ + EK+ Sbjct: 505 FFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKR 538
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 38.7 bits (90), Expect = 1e-04 Identities = 39/206 (18%), Positives = 67/206 (32%), Gaps = 21/206 (10%) Query: 231 LIELEPKLAQALVLKEQSQLALINANKQFESAKLLVNDFDALDKLKQTA------ALLDE 284 L++L A+A LK QS L + + + L +LK +E Sbjct: 124 LLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEE 183 Query: 285 KKQAIEQDKTRLENGQKALQLKPVLDMSLARDAEVVQSQGACVNAQVAKE----SSAQSL 340 + K + Q K + + V ++ E SL Sbjct: 184 VLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSL 243 Query: 341 AHSQ--TQIDVLPEQEQKLQSAQNELQQLSQLLPQLQGFDALQHQVNQAIVQLEQAKQKG 398 H Q + VL EQE K A NEL+ L Q++ + L + + + Q + Sbjct: 244 LHKQAIAKHAVL-EQENKYVEAVNELRVYKSQLEQIES-EILSAK--EEYQLVTQLFKNE 299 Query: 399 IN-----AKGQLDALQAQKQQAEQQL 419 I + L + + E++ Sbjct: 300 ILDKLRQTTDNIGLLTLELAKNEERQ 325 Score = 30.6 bits (69), Expect = 0.037 Identities = 19/157 (12%), Positives = 46/157 (29%), Gaps = 33/157 (21%) Query: 585 ELQMHLHILQQQL----KQTNDAALQLGQLRGQLQEWQTKERALQTQLETEREHFSD--- 637 E+ ++++Q Q L L + R + + + E+ D Sbjct: 183 EVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSS 242 Query: 638 --------------QQSLLAELQGQLKHASTAIPEHYRSVDALNGAIAQVNVQIAVMQQ- 682 Q++ E +L+ + ++ + I + ++ Q Sbjct: 243 LLHKQAIAKHAVLEQENKYVEAVNELR-------VYKSQLEQIESEILSAKEEYQLVTQL 295 Query: 683 ----VINSTRQNHSKAAELDASNTSALAAIQSSLAQA 715 +++ RQ L Q+S+ +A Sbjct: 296 FKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRA 332
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 37.2 bits (86), Expect = 1e-04 Identities = 41/216 (18%), Positives = 87/216 (40%), Gaps = 10/216 (4%) Query: 4 RNRILLTWISFLSYALTGSLIIVTGIVMGDIAKFFNLPISSMSNTFTFLNTGVLISIFFN 63 R+ +L W+ LS+ + +V + + DIA FN P +S + T I Sbjct: 11 RHNQILIWLCILSF-FSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVY 69 Query: 64 VWLMEIISLKKQLIFGFILMLLAVLGLMFGHNLA-IFSGSMFVLGVVSGITMSIGTYLIT 122 L + + +K+ L+FG I+ + GH+ + + F+ G + ++ ++ Sbjct: 70 GKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVA 129 Query: 123 RLYHGKQRGSRLLFTDSFFSMAGMIFPLISAALLAHSIAWYWVYVAIGMIYVAIFILALI 182 R + RG S +M + P I + + +W Y+ + + I + L+ Sbjct: 130 RYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHY---IHWSYLLLIPMITIITVPFLM 186 Query: 183 CEFPALVKSDEQQAVKEKWSLGILFLAIAALCYILG 218 V+ +K GI+ +++ + ++L Sbjct: 187 KLLKKEVRIKGHFDIK-----GIILMSVGIVFFMLF 217
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 64.2 bits (156), Expect = 2e-13 Identities = 92/414 (22%), Positives = 160/414 (38%), Gaps = 45/414 (10%) Query: 1 MKKTLVASALAAVIFVPTASAIEIYKDDKNAVEIGGYVDARIINTQGATEVVNGA-SRIN 59 MK+ ++A + A++ A A EIY D N +++ G VD + +++ + R+ Sbjct: 1 MKRKVLALVIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSDDSSKDGDQTYMRVG 60 Query: 60 FGFTRQMSDGWKAYTKLEWGVNPFGDSKIVYNSNSTFESKSGDFLNNRLGYVGLAHDTYG 119 F Q++D Y + E YN + G RL + GL YG Sbjct: 61 FKGETQINDQLTGYGQWE------------YNVQANTTEGEGANSWTRLAFAGLKFGDYG 108 Query: 120 SITIGKQWGAWYDVVYNTNYGFVWDGNASGTYTYNKADGAINGTGRGDKTVQYRNA--FG 177 S G+ +G YDV T+ + G+ +Y AD + TGR + YRN FG Sbjct: 109 SFDYGRNYGVLYDVEGWTDMLPEFGGD-----SYTYADNYM--TGRANGVATYRNTDFFG 161 Query: 178 ---DFSFAIQAQLKQDTFEIGEVPSASNPLFPAADFMSVKAAGVNVNSSVTTVEYNYTYG 234 +FA+Q Q K ++ +V +N D G ++ TT + + Sbjct: 162 LVDGLNFALQYQGKNESQSADDVNIGTNNRNNGDDIRYDNGDGFGIS---TTYDIGMGFS 218 Query: 235 GAATY---NVTDMLTLTAGFNLGEFEATTSAGKRLTETDSIYGVGATWGNWNSEGVYAAF 291 A Y + T+ G G +A + ++IY + + Sbjct: 219 AGAAYTTSDRTNEQVNAGGTIAGGDKADAWTAGLKYDANNIY-LATMYSE--------TR 269 Query: 292 NVNKQEFHDTDNLGRMMPEAKGLESLASYKFENGIRTFVSYNIL---DAGSEYEAAYNGD 348 N+ D G + + + E A Y+F+ G+R VS+ + D + D Sbjct: 270 NMTPYGKTDKGYDGGVANKTQNFEVTAQYQFDFGLRPAVSFLMSKGKDLTYNNVNGDDKD 329 Query: 349 VFKRQFVVAGVHYVWDSNTVLYLEGRKDYSDFTGVHAEAMAKSEDDGIAIGIRY 402 + K + G Y ++ N Y++ + + D + S DD +A+G+ Y Sbjct: 330 LVK--YADVGATYYFNKNFSTYVDYKINLLDDDDPFYKDAGISTDDIVALGMVY 381
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 36.4 bits (84), Expect = 2e-04 Identities = 29/126 (23%), Positives = 54/126 (42%), Gaps = 3/126 (2%) Query: 42 AAATWMTNAITIAKIIGNLAAAWLLVKMGPKKAFTFASILIVLGALGAFA--SSYPIYVI 99 A+ W+ A + IG L ++G K+ F I+ G++ F S + + ++ Sbjct: 49 ASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIM 108 Query: 100 SRLIMGFGGAFVIVYFNPIVVKYFTAEERPMINGINAAAFNTGNLLAILLTGTLIANFQT 159 +R I G G A +V +Y E R G+ + G + + G +IA++ Sbjct: 109 ARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAI-GGMIAHYIH 167 Query: 160 WQNVIL 165 W ++L Sbjct: 168 WSYLLL 173
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 485 bits (1249), Expect = e-173 Identities = 179/401 (44%), Positives = 262/401 (65%), Gaps = 12/401 (2%) Query: 6 VLVLNCGSSSLKFAVIDAISGEDLLSGLSECFGLEDACIKWKTRVGQQESKHQESLGAFS 65 +LV+NCGSSSLK+ +I++ G L GL+E G+ D+ + + + Sbjct: 3 ILVINCGSSSLKYQLIESKDGNVLAKGLAERIGINDSLLTHNA-----NGEKIKIKKDMK 57 Query: 66 AHTEAMAYIVDTILAAHPTLKQQ---ILAVGHRVVHGGEQFSGSVIINDEVLQGIEACAT 122 H +A+ ++D ++ + + + I AVGHRVVHGGE F+ SV+I D+VL+ I C Sbjct: 58 DHKDAIKLVLDALVNSDYGVIKDMSEIDAVGHRVVHGGEYFTSSVLITDDVLKAITDCIE 117 Query: 123 LAPLHNPAHIIGILAAKVAFPQLAQIAVFDTAFHQTMPQKAFIYALPYQLYREHSIRRFG 182 LAPLHNPA+I GI A P + +AVFDTAFHQTMP A++Y +PY+ Y ++ IR++G Sbjct: 118 LAPLHNPANIEGIKACTQIMPDVPMVAVFDTAFHQTMPDYAYLYPIPYEYYTKYKIRKYG 177 Query: 183 MHGTSHRYICQTAAKTLGIAVEDLNLISAHLGNGASVTAIKAGISVDTSMGMTPLEGVVM 242 HGTSH+Y+ Q AA+ L +E L +I+ HLGNG+S+ A+K G S+DTSMG TPLEG+ M Sbjct: 178 FHGTSHKYVSQRAAEILNKPIESLKIITCHLGNGSSIAAVKNGKSIDTSMGFTPLEGLAM 237 Query: 243 GTRCGDLDPSIIFYLVQNLGYSLKEVEDMMNKQSGLLGISELTNDCRGIEEGH-ANGHKG 301 GTR G +DPSII YL++ S +EV +++NK+SG+ GIS +++D R +E+ NG K Sbjct: 238 GTRSGSIDPSIISYLMEKENISAEEVVNILNKKSGVYGISGISSDFRDLEDAAFKNGDKR 297 Query: 302 ASLALDIFCYRLAKYIASYTVPLGRIDALVFTGGIGENSALIRQKVIELLSIFNFKLDRQ 361 A LAL++F YR+ K I SY +G +D +VFT GIGEN IR+ +++ L FKLD++ Sbjct: 298 AQLALNVFAYRVKKTIGSYAAAMGGVDVIVFTAGIGENGPEIREFILDGLEFLGFKLDKE 357 Query: 362 RNLAARFGQQGQITADTGPV-AMVIPTNEEWVIAQDALKLI 401 +N G++ I+ V MV+PTNEE++IA+D K++ Sbjct: 358 KNKVR--GEEAIISTADSKVNVMVVPTNEEYMIAKDTEKIV 396
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 140 bits (355), Expect = 4e-43 Identities = 85/255 (33%), Positives = 126/255 (49%), Gaps = 19/255 (7%) Query: 2 LNNKICIVTGGAQGIGRCIVETFAQQGALKVYACDMNIEAMRDLEEQYSNVS----AKEL 57 + KI +TG AQGIG + T A QGA + A D N E + + + A Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGA-HIAAVDYNPEKLEKVVSSLKAEARHAEAFPA 64 Query: 58 NVCDRKGIQALIETLKAEHGKIDVLVNNAGITRDNLLDRMSEDDWDMVINVNLKGVFNMT 117 +V D I + ++ E G ID+LVN AG+ R L+ +S+++W+ +VN GVFN + Sbjct: 65 DVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNAS 124 Query: 118 QAVAPLMIENGVGSIITMSSVVGTDGNVGQTNYAATKGGVITMTKGWAKEFSRKGAQVRA 177 ++V+ M++ GSI+T+ S YA++K + TK E + +R Sbjct: 125 RSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYN--IRC 182 Query: 178 NCVAPGFIETPMTIEL------PEKVL-----NFMKGKTPLGRMGKPEDIANGVLFLASD 226 N V+PG ET M L E+V+ F G PL ++ KP DIA+ VLFL S Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTG-IPLKKLAKPSDIADAVLFLVSG 241 Query: 227 NSNFITGQTLKIDGG 241 + IT L +DGG Sbjct: 242 QAGHITMHNLCVDGG 256
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 30.1 bits (68), Expect = 0.019 Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 20/97 (20%) Query: 30 GGEAIKAALAQARVSPEH--LDEVIVGNVL-------SAGQGMGPGRQAA-RYAGIPDTV 79 GG+ I+ + Q++V+ E +D VI ++ A G+ GR AA AG PD Sbjct: 48 GGKVIRDGMGQSQVTREGGAVDTVITNALILDHWGIVKADIGLKDGRIAAIGKAGNPDMQ 107 Query: 80 PAYTLNMICGSGMKTVIEAATKIKAGDADILVAAGME 116 P T+ ++ T++ AG+ I+ A GM+ Sbjct: 108 PGVTI----------IVGPGTEVIAGEGKIVTAGGMD 134
>PF06580#Sensor histidine kinase Length = 349 Score = 28.7 bits (64), Expect = 0.046 Identities = 19/102 (18%), Positives = 36/102 (35%), Gaps = 16/102 (15%) Query: 293 DLLQQVISDQQAAKGDYLPIELLCDETVISVQRDPLTIILNNLVRNSLEHGTEG------ 346 ++ + D L E + ++ VQ P+ ++ LV N ++HG Sbjct: 223 TVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPM--LVQTLVENGIKHGIAQLPQGGK 280 Query: 347 --VIIRQSNSKIEII-----NSMSPHNSSGFGLGLMLV-ERL 380 + + N + + + + G GL V ERL Sbjct: 281 ILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERL 322
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 75.6 bits (186), Expect = 4e-18 Identities = 30/125 (24%), Positives = 60/125 (48%), Gaps = 1/125 (0%) Query: 3 VLLVEDNLLLAKNIIQYLELIDIECDYAGSLAQAEVQVYSRSFDAIILDLNLPDGDGLEA 62 +L+ +D+ + + Q L + + A + + D ++ D+ +PD + + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 63 CKKWKEQRVVSPVIMLTARSGLQDKLSGFEVGADDYLIKPFAMPELVARL-RVVAERRPA 121 + K+ R PV++++A++ + E GA DYL KPF + EL+ + R +AE + Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRR 125 Query: 122 PKVLR 126 P L Sbjct: 126 PSKLE 130
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 110 bits (277), Expect = 2e-31 Identities = 74/263 (28%), Positives = 128/263 (48%), Gaps = 22/263 (8%) Query: 3 LKDKVVVITGGAGGLGYAMAENLAAAGAKLALIDVDQEKLEKACANIGATTEVQ-GYAVD 61 ++ K+ ITG A G+G A+A LA+ GA +A +D + EKLEK +++ A + D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 62 ITDEEDVFATFQFIKEDFGRVNVLINNAGILRDGLLLKAKEGQVFERMSFEQFQSVINVN 121 + D + I+ + G +++L+N AG+LR GL+ +S E++++ +VN Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLI---------HSLSDEEWEATFSVN 116 Query: 122 LTGSFLCGREAAAAMIETEQEGVIINISSLAKAGNVGQTNYAASKAGVAAMSVGWAKELA 181 TG F R + M++ ++ S+ A YA+SKA + ELA Sbjct: 117 STGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELA 176 Query: 182 RYNIRSAAVAPGVIETEMTAAMKPE----------ALERLEKMVPVGRLGQAEEIASTVR 231 YNIR V+PG ET+M ++ + +LE + +P+ +L + +IA V Sbjct: 177 EYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVL 236 Query: 232 FIIEND--YVNGRVFEIDGGIRL 252 F++ ++ +DGG L Sbjct: 237 FLVSGQAGHITMHNLCVDGGATL 259
>PF01540#Adhesin lipoprotein Length = 475 Score = 29.3 bits (65), Expect = 0.041 Identities = 21/64 (32%), Positives = 28/64 (43%) Query: 31 ETIAVVNAAVDAEVLTAVASAKQAFQSWKEVPVSERARVMLRYQHLLKEHHDEIATILAQ 90 +T A VN +L+ + S K+ SW E VSE V + L E E LA+ Sbjct: 181 KTFATVNTIKKDFLLSELESFKEFNTSWLEKIVSEWEEVKKAWSKELAEIKAEDDKKLAE 240 Query: 91 ETGK 94 E K Sbjct: 241 ENQK 244
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 81.6 bits (201), Expect = 3e-20 Identities = 53/197 (26%), Positives = 91/197 (46%), Gaps = 17/197 (8%) Query: 4 EGQVAIVTGAASGLGRAYAIALAERGARVVLVDNETTQTKDVSSSMTNLEPDSGLQACGA 63 EG++A +TGAA G+G A A LA +GA + VD + + V SS+ Sbjct: 7 EGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLK------------- 53 Query: 64 AITALGGEFKSFTLDVTSIDDINSMVDDVVKSWGRVDILINNAGIHKSCAFEQMSASSWK 123 A ++F DV I+ + + + G +DIL+N AG+ + +S W+ Sbjct: 54 ---AEARHAEAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWE 110 Query: 124 HNLDVDLNGTFYMTQAVWPFMKRQSYGRVV-MSSASSIYGDMYETSFSTSKMAVMGLVNS 182 V+ G F +++V +M + G +V + S + ++++SK A + Sbjct: 111 ATFSVNSTGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKC 170 Query: 183 LHLEGAEHGIKVNSIIP 199 L LE AE+ I+ N + P Sbjct: 171 LGLELAEYNIRCNIVSP 187
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.1 bits (73), Expect = 0.005 Identities = 21/105 (20%), Positives = 43/105 (40%), Gaps = 3/105 (2%) Query: 1 MKNQSNLYDIGVIG-LGVMGKNLALNIADNQYRVAAFDLDELKVQDTVAQEELERKR--Y 57 + + S+L I V+ + A N+ RV L++++ + A+EE + + Sbjct: 237 LDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLF 296 Query: 58 LKQITEPRIEGCNNLSEMLSKLEKPRVLLLSVPAGAPVDGVCQSL 102 +I + + +N+ + +L K + APV Q L Sbjct: 297 KNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQL 341
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.3 bits (71), Expect = 0.014 Identities = 20/112 (17%), Positives = 35/112 (31%), Gaps = 12/112 (10%) Query: 543 NLLTLSGELIDEILHAEIVQHKLGDSQAEQASKANGHKIKLPVSQVGNDFTLFINSKSYH 602 +L + ++ E+ +K Q E K V F I K Sbjct: 253 AVLEQENKYVE--AVNELRVYKSQLEQIESEIL----SAKEEYQLVTQLFKNEILDKLRQ 306 Query: 603 YRALESEEIEEQDNLEDKL-----KAPMNGTIVTQLV-SVGDVVKAGQGIMV 648 E E++ +AP++ + V + G VV + +MV Sbjct: 307 TTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMV 358
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 30.6 bits (69), Expect = 0.013 Identities = 37/195 (18%), Positives = 78/195 (40%), Gaps = 33/195 (16%) Query: 261 PFIDFFKRYGRSAILILLLISCYRISDIVMGIMANVFYV---DMGFSKTEIATLSKIYGL 317 PF+D G++ ++ ++ I V G ++ V Y+ S EI ++ G Sbjct: 246 PFVDP--GLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGT 303 Query: 318 IMTLVGAGAGGLLIARYGTMKILFLGAFLVAVTNLLFAYQAMIGYDVSFLTFAISVDNFS 377 + ++ GG+L+ R G + +L +G ++ VSFLT + ++ Sbjct: 304 MSVIIFGYIGGILVDRRGPLYVLNIGVTFLS---------------VSFLTASFLLE--- 345 Query: 378 AGIATAAFIAYLSSLTSSGYSATQYALLSSI-MLLFPKFVAGFSGAYIDAYDYVSFFIAA 436 T+ F+ + G S T+ + + + L + GA + ++ SF Sbjct: 346 ---TTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEA----GAGMSLLNFTSFLSEG 398 Query: 437 SLIGFPVLGLIMLVQ 451 G ++G ++ + Sbjct: 399 --TGIAIVGGLLSIP 411
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 33.1 bits (75), Expect = 0.001 Identities = 15/60 (25%), Positives = 31/60 (51%), Gaps = 3/60 (5%) Query: 44 PIVIGTNKLALLASGINNVRRYAFSMDLPWPLIVP--AIISGCICAFIGSSLLDHVSEAW 101 P+ + K A +G++ V FS+ L + AI++G +C++I + L+ ++E Sbjct: 462 PLFLTLEKKAA-DAGVSYVVALLFSLLAGTTLGIWGIAIVTGILCSYIDKNKLNTINEVL 520
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 27.1 bits (60), Expect = 0.035 Identities = 17/53 (32%), Positives = 24/53 (45%), Gaps = 1/53 (1%) Query: 51 EPVTIAASDKTNIIAMIAGAAIGGILGSEVGGGAGSDI-AAIGGSVAGGYAGS 102 E +A + I M + A I G+L + GAGS A+G V GG + Sbjct: 961 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSA 1013
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 34.8 bits (80), Expect = 0.001 Identities = 24/133 (18%), Positives = 48/133 (36%), Gaps = 15/133 (11%) Query: 30 LQKVQKKQQSAAAKQQKQQKVEQQIAITGKPF-WWLMTMFICSVVYLFPEAIFNAALTDV 88 L + K ++ ++ + A + FI +V P A++ V Sbjct: 181 LPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALW------V 234 Query: 89 AGGRNASHDDLRAVELFGRTISGIGVTLLLADMLLSGKRVARVGH----ALGYFSLIAVL 144 G + H D + G +++ G+ LA +++G AR+G LG + Sbjct: 235 IFGEDRFHWDATTI---GISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGY 291 Query: 145 VWPTVFFGQKWLV 157 + F + W+ Sbjct: 292 IL-LAFATRGWMA 303
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 41.5 bits (97), Expect = 2e-06 Identities = 40/156 (25%), Positives = 60/156 (38%), Gaps = 9/156 (5%) Query: 10 LLTACALPSAFALADNAAPA----KRIVALSPHSVEMLYAIGAGESIVATTDHADF---- 61 LLTA AL + A A RIVAL VE+L A+G VA T + Sbjct: 12 LLTAMALSPLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSE 71 Query: 62 PEAALQIPRIGGYYGIQIERVLELEPDLVVVWSG-GNKAEDIARIKELGFRVFDSNPSTL 120 P + +G +E + E++P +V +G G E +ARI F L Sbjct: 72 PPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGRGFNFSDGKQPL 131 Query: 121 ELVADELVSLGELTGHQAQATKVADDYRQQLSQLRS 156 + L + +L Q+ A Y + ++ Sbjct: 132 AMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKP 167
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 27.1 bits (59), Expect = 0.037 Identities = 13/65 (20%), Positives = 27/65 (41%), Gaps = 3/65 (4%) Query: 13 KSRFAEAQVAELQNNVDSECFYFATAQALDSEMAQRIRHHQTQRESDTINWRAIECPLEL 72 +++ AE+ + Q+N+ E F A + +QR +H+ D + P+ L Sbjct: 305 RTQLAESGIQLGQSNISGESFSGQQQAASQQQQSQRTANHEPLAGEDDD---TLPVPVSL 361 Query: 73 TAALK 77 + Sbjct: 362 QGRVT 366
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 30.7 bits (69), Expect = 0.043 Identities = 14/71 (19%), Positives = 30/71 (42%), Gaps = 5/71 (7%) Query: 361 SGLEPLTIDDNSLFLNVGERTN---VTGSAKFLRLIKTGEYEEALSVAREQVESGAQIID 417 +P+ D ++ + +TN VT + + ++ L + R QV A I + Sbjct: 298 QAAKPVAALDKNIIIKAHGQTNALIVTAAPDVMNDLE--RVIAQLDIRRPQVLVEAIIAE 355 Query: 418 INMDEGMLDGV 428 + +G+ G+ Sbjct: 356 VQDADGLNLGI 366
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 1026 bits (2654), Expect = 0.0 Identities = 376/567 (66%), Positives = 451/567 (79%), Gaps = 2/567 (0%) Query: 3 KISRQAYADMFGPTVGDRVRLADTALMLEVEQDLTTYGEEVKFGGGKVIRDGMGQSQAL- 61 ++SR AYA+MFGPTVGD+VRLADT L +EVE+D TT+GEEVKFGGGKVIRDGMGQSQ Sbjct: 4 RMSRAAYANMFGPTVGDKVRLADTELFIEVEKDFTTHGEEVKFGGGKVIRDGMGQSQVTR 63 Query: 62 SKDCVDAVITNALILDHWGIVKADIGIKHGRIVGIGKAGNPDVQPNVDIVIGAGTEAIAG 121 VD VITNALILDHWGIVKADIG+K GRI IGKAGNPD+QP V I++G GTE IAG Sbjct: 64 EGGAVDTVITNALILDHWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAG 123 Query: 122 EGKIITAGAIDTHVHFICPQQVEEALCAGTTTFIGGGTGPVAGSTATTVTPGIWNMHRML 181 EGKI+TAG +D+H+HFICPQQ+EEAL +G T +GGGTGP G+ ATT TPG W++ RM+ Sbjct: 124 EGKIVTAGGMDSHIHFICPQQIEEALMSGLTCMLGGGTGPAHGTLATTCTPGPWHIARMI 183 Query: 182 EAADELPINVGLFGKGTVSNPDAIREQIANGAMGLKIHEDWGATPAAIDTCMTVADEMDV 241 EAAD P+N+ GKG S P A+ E + GA LK+HEDWG TPAAID C++VADE DV Sbjct: 184 EAADAFPMNLAFAGKGNASLPGALVEMVLGGATSLKLHEDWGTTPAAIDCCLSVADEYDV 243 Query: 242 QVAIHSDTLNEGGFYEATTKAIGDRVIHVFHTEGAGGGHAPDVIKSVGEPNIIPASTNPT 301 QV IH+DTLNE GF E T AI R IH +HTEGAGGGHAPD+I+ G+PN+IP+STNPT Sbjct: 244 QVMIHTDTLNESGFVEDTIAAIKGRTIHAYHTEGAGGGHAPDIIRICGQPNVIPSSTNPT 303 Query: 302 MPYTINTVDEHLDMLMVCHHLDPAIAEDVAFAESRIRRETIAAEDILHDLGAISVMSSDS 361 PYT+NT+ EHLDMLMVCHHL P I ED+AFAESRIR+ETIAAEDILHD+GA S++SSDS Sbjct: 304 RPYTVNTLAEHLDMLMVCHHLSPTIPEDIAFAESRIRKETIAAEDILHDIGAFSIISSDS 363 Query: 362 QAMGRVAEVAMRTWQCAHKMKLQRGPLEGDSELSDNTRLKRYVAKYTINPAITHGISHEV 421 QAMGRV EVA+RTWQ A KMK QRG L+ ++ +DN R+KRY+AKYTINPAI HG+SHE+ Sbjct: 364 QAMGRVGEVAIRTWQTADKMKRQRGRLKEETGDNDNFRVKRYIAKYTINPAIAHGLSHEI 423 Query: 422 GSIEKGKLADIVLWDPAFFGVKPALVLKGGLAVYAPMGDINGAIPTPQPVHYRPMYAATG 481 GS+E GK AD+VLW+PAFFGVKP +VL GG APMGD N +IPTPQPVHYRPM+ A G Sbjct: 424 GSLEVGKRADLVLWNPAFFGVKPDMVLLGGTIAAAPMGDPNASIPTPQPVHYRPMFGAYG 483 Query: 482 KARAATSMTFLPKAAIEAGITEKLKLTHLIGEVKGCR-NIRKKDMIHNSYTPVIELDSQT 540 ++R +S+TF+ +A+++AG+ +L + + V+ R I K MIHNS TP IE+D +T Sbjct: 484 RSRTNSSVTFVSQASLDAGLAGRLGVAKELVAVQNTRGGIGKASMIHNSLTPHIEVDPET 543 Query: 541 YVVKADGMALVCEPLAELPMAQRYFLF 567 Y V+ADG L CEP LPMAQRYFLF Sbjct: 544 YEVRADGELLTCEPATVLPMAQRYFLF 570
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 47.8 bits (113), Expect = 2e-07 Identities = 50/307 (16%), Positives = 104/307 (33%), Gaps = 33/307 (10%) Query: 46 RLNSESPKNEALISQYETLLSRVNGYKKQKATRDEYRNIISQFPVQRERLLKKI-NDVEQ 104 + N+ L + ++ K + + + E+ L+ N Sbjct: 79 NNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTA 138 Query: 105 LDIFNVLHKTKYNDLSQSIATLQAAVTEWRSTSQSNSDKNKQLINASTTLPQSLAQIDRE 164 + + L+ A L+ A+ + S ++S K K L L A++++ Sbjct: 139 DSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKA 198 Query: 165 IEKA---SIIKSDTDGQLDQWLESSN---------LTTLKLQRQVTSAQLQSLDERTELL 212 +E A S S L+ + L SA++++L+ L Sbjct: 199 LEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAAL 258 Query: 213 GLEQQLLNKKIQTASPILIELQDKLTRVEQASVKTLIEQARKISEDSALKG--------- 263 Q L K ++ A K+ +E E+A + L Sbjct: 259 EARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDL 318 Query: 264 -----------AENQQQIEQLKAYTVELEQVLAEIDQARISYQKVEAEQRSLMDEQRLIK 312 AE+Q+ EQ K + + ++D +R + +++EAE + L ++ ++ + Sbjct: 319 DASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISE 378 Query: 313 NNLAWLR 319 + LR Sbjct: 379 ASRQSLR 385
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 30.5 bits (69), Expect = 0.012 Identities = 24/106 (22%), Positives = 39/106 (36%), Gaps = 8/106 (7%) Query: 169 YTWESSDWKVKPYAEFQWK-SADFNDYYYGLGQYEVGGGVS-FNAGVKARYHVISNLYLL 226 + E+ V ++ +K D + + Q E ++ ++G R I L Sbjct: 45 ASVETGTGIVDLGSKIGFKGQEDLGNGLKAIWQVEQKASIAGTDSGWGNRQSFIG---LK 101 Query: 227 GQFG---VGRLEDDVYDLPTINNRFQYESFFGFGFFPEPNSKKYSA 269 G FG VGRL + D IN + G EP ++ S Sbjct: 102 GGFGKLRVGRLNSVLKDTGDINPWDSKSDYLGVNKIAEPEARLISV 147
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 51.2 bits (122), Expect = 1e-10 Identities = 20/75 (26%), Positives = 37/75 (49%) Query: 1 MAKRSKIQTKQTVQQILDEAMKQILDLGYDAMSYSTLSEATGISRTGISHHFPHKIDFLK 60 MA+++K + ++T Q ILD A++ G + S +++A G++R I HF K D Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 QLDSRIANLFIERLD 75 ++ + E Sbjct: 61 EIWELSESNIGELEL 75
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 30.6 bits (69), Expect = 0.007 Identities = 10/37 (27%), Positives = 21/37 (56%) Query: 348 GCFDILHAGHVSYLQQARALGDRLIVAVNTDASVKRL 384 G FD + GH+ +++ L D++ VAV + + + + Sbjct: 7 GSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPM 43
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 385 bits (990), Expect = e-131 Identities = 132/370 (35%), Positives = 201/370 (54%), Gaps = 17/370 (4%) Query: 166 KLEKQAVQSQE--PSSFNHSSDSEVEIIGQSPTMQAMQNELSVVASTDLNVLILGDTGTG 223 + +A+ + PS S + ++G+S MQ + L+ + TDL ++I G++GTG Sbjct: 113 GIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTG 172 Query: 224 KELVAKSIHLHSLRANKPLVYLNCAALPESVAESELFGHVKGAFTGAISHRSGKFEIADN 283 KELVA+++H + R N P V +N AA+P + ESELFGH KGAFTGA + +G+FE A+ Sbjct: 173 KELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEG 232 Query: 284 GTLFLDEIGELPLSLQSKLLRVLQYGDLQKVGSDKSLKVDVRIIAATNKDLKQEVLAGRF 343 GTLFLDEIG++P+ Q++LLRVLQ G+ VG ++ DVRI+AATNKDLKQ + G F Sbjct: 233 GTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLF 292 Query: 344 RADLYHRLSVFPILVPPLNEREGDVILLSGFFVERSREKLGLKSLSLSPDSISLLNNYDW 403 R DLY+RL+V P+ +PPL +R D+ L FV+++ K GL +++ L+ + W Sbjct: 293 REDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAE-KEGLDVKRFDQEALELMKAHPW 351 Query: 404 PGNVRELEHVLRRAAVLSRAQSQSDTAVITPQHFDLRGQDS-PQLDSAFKTVTKASHSVA 462 PGNVRELE+++RR L VIT + + + P S S++ Sbjct: 352 PGNVRELENLVRRLTALYPQD------VITREIIENELRSEIPDSPIEKAAARSGSLSIS 405 Query: 463 IAQGQN-------QTNNQTNNQTLKQATEAFQAQYIRQALVGNGNNWAATARALDVDSGN 515 A +N + + + + I AL N A L ++ Sbjct: 406 QAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNT 465 Query: 516 LHRLAKRIGI 525 L + + +G+ Sbjct: 466 LRKKIRELGV 475
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 62.3 bits (151), Expect = 5e-14 Identities = 38/160 (23%), Positives = 58/160 (36%), Gaps = 10/160 (6%) Query: 51 ELPLLPPEKPKLPTPKEVQSKPVTASAATPVSSSIPIMPSVADMPLQVPVLAIPTLNGLS 110 E P++ + P PK K V + P + T Sbjct: 89 EAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTAT----- 143 Query: 111 LPSIAPVIAGIKDVDKAPELLRFIQPKMPVAGRKFKGGGRVLLRLIVEADGVVSQAQVLE 170 A + V P L QP+ P + + G+V ++ V DG V Q+L Sbjct: 144 ----AATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILS 199 Query: 171 AKPKQVFDQSAVEAARRWRFKPAVLSGEAVRVFVDVPINF 210 AKP +F++ A RRWR++P G + V + IN Sbjct: 200 AKPANMFEREVKNAMRRWRYEPG-KPGSGIVVNILFKING 238
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.6 bits (69), Expect = 0.016 Identities = 25/126 (19%), Positives = 54/126 (42%), Gaps = 12/126 (9%) Query: 17 FAQKSATQETASVKGSAEYQALERRVD--QRASEVERQNLLWSSNL-------KQEIDEV 67 + + +E K AE + R++ + S VE+ L S+L K + E Sbjct: 198 WQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQ 257 Query: 68 KTNQQQLTKRLKTKRGQLEQLNQQLIDLNQQKQSLSQDYQLAVDDMKLVQGAYQKALSSL 127 + + L+ + QLEQ+ +++ ++ Q ++Q ++ + D KL Q + L Sbjct: 258 ENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILD-KLRQ--TTDNIGLL 314 Query: 128 SQQWQQ 133 + + + Sbjct: 315 TLELAK 320
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.8 bits (69), Expect = 0.012 Identities = 27/118 (22%), Positives = 40/118 (33%), Gaps = 14/118 (11%) Query: 30 LAILGANGAGKTTLINCLCGLNQPSEGAVHLNSRALDKMSRAEIAQQMALVPQQQETAFA 89 + + G G GK+TLIN L GL+ S+ + E + + TAF Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIG----TGKDSYEQIAGIVAYELSEMTAFR 654 Query: 90 FTALEMVVMGRTPFLS----TFESPSEQDINDAKRVMQLLDVGGLAKADYNRLSGGER 143 E V F S + + + D R Q++ K Y G R Sbjct: 655 RADAEAV----KAFFSSRKDRYRGAYGRYVQDHPR--QVVIWCTTNKRQYLFDITGNR 706
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 27.5 bits (61), Expect = 0.050 Identities = 8/26 (30%), Positives = 16/26 (61%) Query: 196 PIKLERERLGWWVMGFLFIFFVVAYL 221 P+ + +++MGFL I F+++ L Sbjct: 52 PVSRRPRLVAYFIMGFLVIAFILSVL 77
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.006 Identities = 8/22 (36%), Positives = 14/22 (63%) Query: 28 VLGISGPSGVGKSSLASVLAGM 49 + + G G+GKS+L + L G+ Sbjct: 598 SVVLEGTGGIGKSTLINTLVGL 619
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 37.8 bits (88), Expect = 1e-04 Identities = 24/96 (25%), Positives = 42/96 (43%), Gaps = 20/96 (20%) Query: 16 LIKNATVIDGTGGAAFKGDVLIDNQLII--------DVAPLIEL---AADSVIDAGGAYL 64 +I NA ++D G K D+ + + I D+ P + + VI G + Sbjct: 71 VITNALILDHWG--IVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIV 128 Query: 65 TPGFIDVHSHSDLATFL-PQGFKPKVLQGITTELIG 99 T G +D H H F+ PQ + ++ G+T ++G Sbjct: 129 TAGGMDSHIH-----FICPQQIEEALMSGLTC-MLG 158
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 29.9 bits (67), Expect = 0.015 Identities = 17/66 (25%), Positives = 28/66 (42%) Query: 130 KGQDSEFVFTVDFVDAVQGVEKVVELPVNGETKKIKVKIPAGIKDGEKIRFTGKGSAGVN 189 KG D V V AV +++ G + +++I + + DG+ F GSA + Sbjct: 574 KGVDKWTVKGVQDKGAVYDYSNLIQHASVGNNQYREIRIESHLGDGDDKVFLSAGSANIY 633 Query: 190 GGAAGD 195 G D Sbjct: 634 AGKGHD 639
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 29.8 bits (67), Expect = 0.025 Identities = 19/113 (16%), Positives = 48/113 (42%), Gaps = 12/113 (10%) Query: 169 MMLAALINLILDPLLIFGIGPFPRLEIEGAAIATVISWVVALSLSTHLLIFKRHLVDFVE 228 L A++ L+ D LL G+ +L+ + +A +++ + S++ +++F R + Sbjct: 178 FALGAVVALVHDVLLTVGLFAVLQLKFDLTTVAALLT-ITGYSINDTVVVFDR-----LR 231 Query: 229 PNLERLKCNWKQLAHIAQPAAMMNLLNPLANAIIMAMLARIDHSAVAAFGAGT 281 NL + K L + +++ L+ ++ M + + +G Sbjct: 232 ENLIKYK--TMPLRDVMN----LSVNETLSRTVMTGMTTLLALVPMLIWGGDV 278
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 44.8 bits (106), Expect = 4e-07 Identities = 28/200 (14%), Positives = 67/200 (33%), Gaps = 29/200 (14%) Query: 104 EADYELAKADFKRKGELLRRELISQAEYDLASAQLKSS--KANLASAQDQLSYTELTAPY 161 E++ AK +++ +L + E++ + L LA +++ + + AP Sbjct: 279 ESEILSAKEEYQLVTQLFKNEILDK----LRQTTDNIGLLTLELAKNEERQQASVIRAPV 334 Query: 162 DGTVAKISI-DNYQMVQANQPVL-VLQKDSDIDIVIQVPESLASKVTQFNPNAVTQPV-V 218 V ++ + +V + ++ ++ +D +++ V + V Q + Sbjct: 335 SVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFIN------VGQNAII 388 Query: 219 RFANDPSVAYPVL------------LKEHATQVTPGTQSYEVVFTLARPSNMTVLPGMSA 266 + P Y L + V S E N+ + GM+ Sbjct: 389 KVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAV 448 Query: 267 ELTMDIAQQKSQALTAILPP 286 +I ++ +L P Sbjct: 449 T--AEIKTGMRSVISYLLSP 466 Score = 33.3 bits (76), Expect = 0.001 Identities = 18/83 (21%), Positives = 31/83 (37%), Gaps = 7/83 (8%) Query: 78 EGQQVKKAMVLARLDRRDAQNTLLNREADYELAKADFKRKGELLR-------RELISQAE 130 EG+ V+K VL +L A+ L ++ A+ + R L R EL E Sbjct: 114 EGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDE 173 Query: 131 YDLASAQLKSSKANLASAQDQLS 153 + + + ++Q S Sbjct: 174 PYFQNVSEEEVLRLTSLIKEQFS 196
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 494 bits (1274), Expect = e-160 Identities = 203/1053 (19%), Positives = 436/1053 (41%), Gaps = 61/1053 (5%) Query: 4 AEYSITHKVISWMFALLLLIGGTVSFFSLGQLEFPEFTIKQALVVTTYPGASPEQVEEEV 63 A + I + +W+ A++L++ G ++ L ++P V YPGA + V++ V Sbjct: 2 ANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTV 61 Query: 64 TLPLEDALQQLDGIKHITSV-NSAGLSQIEIEIKENYDASELPQVWDEVRRKVNDKAVEL 122 T +E + +D + +++S +SAG I + + D +V+ K+ L Sbjct: 62 TQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTD---PDIAQVQVQNKLQLATPLL 118 Query: 123 PPGVHTPSVIDDFGD---VYGILLNVSGDGYSDRELQNYADF-LRRELVLVDGIKKVTIA 178 P V + + + G + ++ +Y ++ L ++G+ V + Sbjct: 119 PQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLF 178 Query: 179 GGVNEQVVVEISQQKLNALGLDQNYIYGLINSQNVVSNAGSMLVGDN------RIRIHPT 232 G + + + LN L + + QN AG + I Sbjct: 179 GA-QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQ 237 Query: 233 GEFDNVRQMERLLISPPGSPKLIYLGDIAKIYKGSEETPSNIYHTDGKQALSIGIAFSSG 292 F N + ++ + ++ L D+A++ G E + I +GK A +GI ++G Sbjct: 238 TRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGEN-YNVIARINGKPAAGLGIKLATG 296 Query: 293 VNVVKVGEAVNQRMSELYSELPIGMTLNTVYDQSKMVDQTVNGFLVNLAESVAIVIGVLL 352 N + +A+ +++EL P GM + YD + V +++ + L E++ +V V+ Sbjct: 297 ANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMY 356 Query: 353 IFMG-VRSGLLMGLVLLLTILGTFIVMNVLNIELQIISLGALIIALGMLVDNAIVVTEGI 411 +F+ +R+ L+ + + + +LGTF ++ + +++ +++A+G+LVD+AIVV E + Sbjct: 357 LFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENV 416 Query: 412 L-IGIKRGQTRLETAKQVVSQTQWPLLGATIIAIIAFAPIGLSDNATGEFCASLFQVLLI 470 + ++ E ++ +SQ Q L+G ++ F P+ +TG ++ Sbjct: 417 ERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVS 476 Query: 471 SLFISWITAMTLTPFFCNLMFKDGVISEDENDDPYKGWLFAIYRQSLNLA-------MRF 523 ++ +S + A+ LTP C + K EN + GW + S+N + Sbjct: 477 AMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGS 536 Query: 524 RSLTLILVIAALVSSVIGFGHVKNVFFPASNTPIFFVDVWMPEGSDIKATERLLSRIEAD 583 L++ + V+ F + + F P + +F + +P G+ + T+++L ++ Sbjct: 537 TGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDY 596 Query: 584 LLQQQKEQDTGLVNLTTVIGQG-AQRFVLSYVPEKGYKAYGQILLEMTDLTTLNQYMRVL 642 L+ +K + + G AQ +++V K ++ + + Sbjct: 597 YLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWE----------ERNGDENSAEAV 646 Query: 643 ERELSLKFPEAEYRFKYMENGPS---------PAAKIEARFYGEDPQVLRQLAVQAEDIL 693 ++ + F N P+ ++ + + + Sbjct: 647 IHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAA 706 Query: 694 KAEPTAVGVRHNWRNQVTLVRPQLAQAQARETGISKQDLDNALLTNFSGKQIGTYRENSH 753 + + V VR N + ++ Q +A+ G+S D++ + T G + + + Sbjct: 707 QHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGR 766 Query: 754 LLPIIARAPDEERLDAQSIWKLQVWSSDNHTFVPVTQVVSDFSTEWEDPLIMRRDRKRVI 813 + + +A + R+ + + KL V S N VP + + P + R + + Sbjct: 767 VKKLYVQADAKFRMLPEDVDKLYV-RSANGEMVPFSAFT-TSHWVYGSPRLERYNGLPSM 824 Query: 814 SVLADPLNGTRETADSVFRKVKADIEAIP--LPAGYELEWGGEYETSMEAQESVFSSIPL 871 + + G + A +E + LPAG +W G + + + + Sbjct: 825 EIQGEAAPG------TSSGDAMALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAI 878 Query: 872 GYLAMFIITVLLFNSVRQPLVIWFTVPLALIGVVSGLLIFDAPFSFMALLGLLSLTGMII 931 ++ +F+ L+ S P+ + VPL ++GV+ +F+ ++GLL+ G+ Sbjct: 879 SFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSA 938 Query: 932 KNGIVLVDQIN-LELSSGKEAYQAVVDSAVSRVRPVLMAAITTMLGMLPLISDAFFGS-- 988 KN I++V+ L GK +A + + R+RP+LM ++ +LG+LPL GS Sbjct: 939 KNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGA 998 Query: 989 ---MAITIIFGLGFASVLTLIVLPVTYTLAFRI 1018 + I ++ G+ A++L + +PV + + R Sbjct: 999 QNAVGIGVMGGMVSATLLAIFFVPVFFVVIRRC 1031
>DNABINDNGFIS#DNA-binding protein FIS signature. Length = 98 Score = 119 bits (299), Expect = 7e-39 Identities = 59/101 (58%), Positives = 82/101 (81%), Gaps = 3/101 (2%) Query: 1 MFDQTTHTEVHQLTVGKIETASGAIKPQLLRDAVKRAVTNFFAQMDGQEAEEVYEMVLSE 60 MF+Q +++V LTV + + + + LRD+VK+A+ N+FAQ++GQ+ ++YE+VL+E Sbjct: 1 MFEQRVNSDV--LTVSTVNSQDQVTQ-KPLRDSVKQALKNYFAQLNGQDVNDLYELVLAE 57 Query: 61 VEAPLLDIIMQHTRGNQTRAANMLGINRGTLRKKLKKYGMN 101 VE PLLD++MQ+TRGNQTRAA M+GINRGTLRKKLKKYGMN Sbjct: 58 VEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN 98
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 741 bits (1914), Expect = 0.0 Identities = 216/1052 (20%), Positives = 429/1052 (40%), Gaps = 47/1052 (4%) Query: 7 RLAINRRWMMMFLAMLLVAVGLWSYQKLPIDAVPDITNVQVQISTRAEGYSPQETEQRIT 66 I R LA++L+ G + +LP+ P I V +S G Q + +T Sbjct: 3 NFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVT 62 Query: 67 YPIENALMGIPQLSYTRSLS-RYGLSQVTVVFDEGTDLYFARNLISERLNGIKGKLPAEI 125 IE + GI L Y S S G +T+ F GTD A+ + +L LP E+ Sbjct: 63 QVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEV 122 Query: 126 EPEMGPISTGLGEIFMYTIEALPDAKQADGREFDATALREIQDWIIKPQLAQVPGVTEIN 185 + + + M +D + + +K L+++ GV ++ Sbjct: 123 QQQGISVEKSSSSYLMVA------GFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQ 176 Query: 186 TIGGYDKEYHITPLPEQMLAYGVSFADIKVALLNSNSNRGAGYIER----EGQQLTVRSA 241 G I + + Y ++ D+ L N AG + GQQL Sbjct: 177 LFGA-QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASII 235 Query: 242 AQ--LKTMSDIEQVVVK-HIDNAPIFITDIAEVGIGKALRTGAATRDGKETVLGSAMMLV 298 AQ K + +V ++ + D + + + D+A V +G A +GK + Sbjct: 236 AQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLAT 295 Query: 299 GENSRQVSLAVAAKLEDVKASLPDGIKVEAVYDRTTLVDKAVYTVQKNLVEGALLVIVVL 358 G N+ + A+ AKL +++ P G+KV YD T V +++ V K L E +LV +V+ Sbjct: 296 GANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVM 355 Query: 359 FILLGNARAALITAAVIPLAMLATMTGMVQAGVSANLMSLG--ALDFGLIVDGAVIIVEN 416 ++ L N RA LI +P+ +L T + G S N +++ L GL+VD A+++VEN Sbjct: 356 YLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVEN 415 Query: 417 AIRRLGQAQVQNGGHVLGRKQRLQLVFEATNEVIRPSLFGVLIITVVYIPLFSLTGVEGK 476 R + + + + ++ +++ + ++++ V+IP+ G G Sbjct: 416 VERVM----------MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGA 465 Query: 477 MFHPMAATVVMALLAALVLSLTLVPAAVALFMTGKISDKE----------SRVITATKSL 526 ++ + T+V A+ +++++L L PA A + ++ + + + Sbjct: 466 IYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNH 525 Query: 527 YKPLLIAAMKLRWLVLSAAVALVAFSIWLATTLGSEFIPQLNEEDILLQAIRIPGTGLEQ 586 Y + + L +VA + L L S F+P+ ++ L G E+ Sbjct: 526 YTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQER 585 Query: 587 SVDMQVLLEERIKHFPQVLNVFSKIGTPEVANDPMPPNIADTFIMLKPRSEWPNPKMSHD 646 + + + + + NV S + N F+ LKP E + S + Sbjct: 586 TQKVLDQVTDYYLKNEKA-NVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAE 644 Query: 647 ALAADIVTAVSGQPGNNFELTQPIEM-RFNELISGVRADLG-IKVVGDDLQQLLTSANAI 704 A+ + P M EL + D I G L + N + Sbjct: 645 AVIHRAKMELGKIRDGF---VIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQL 701 Query: 705 HEVLEQ-IDGVADLQVEQVTGLPMLSIQPDRMALARYGLTVNELQDFVATAIGGEEAGLI 763 + Q + ++ + ++ D+ G++++++ ++TA+GG Sbjct: 702 LGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDF 761 Query: 764 FEGDRRFKMVIRLPETIRKDVEHLQELPIVLPSGEYVPLSEVASLDIAPSPNQISRENGK 823 + R K+ ++ R E + +L + +GE VP S + ++ R NG Sbjct: 762 IDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGL 821 Query: 824 RRIVVTANVRGRDLGSFVSEAKLRINQQVDIPAGYWLEYGGTFEQLESASQRLSIVVPLT 883 + + + + +PAG ++ G Q + + +V ++ Sbjct: 822 PSMEIQGEAAPGTSSGDAMALMENLASK--LPAGIGYDWTGMSYQERLSGNQAPALVAIS 879 Query: 884 LALILGLLVMAFSSVKDALIIFTGIPLALTGGVISLWLRDMPLSISAGVGFIALSGVAVL 943 ++ L + S + + +PL + G +++ L + + VG + G++ Sbjct: 880 FVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAK 939 Query: 944 NGLVLLSFIRQLYQEKGE-LMSAIIDGALIRLRPVLMTALVAGLGFVPMALNIGTGAEVQ 1002 N ++++ F + L +++G+ ++ A + +RLRP+LMT+L LG +P+A++ G G+ Q Sbjct: 940 NAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQ 999 Query: 1003 RPIATVVIGGIISSTLLTLFVLPILYRMAHQR 1034 + V+GG++S+TLL +F +P+ + + + Sbjct: 1000 NAVGIGVMGGMVSATLLAIFFVPVFFVVIRRC 1031
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.3 bits (71), Expect = 0.007 Identities = 12/79 (15%), Positives = 27/79 (34%), Gaps = 5/79 (6%) Query: 80 GYYLYQQLQAQQAETAALQQELKQELQTVLVAPNQRITSLEQQ----QNQFKSSVDSTLK 135 + Q+ + EL+ + I S +++ FK+ + L+ Sbjct: 247 QAIAKHAVLEQENKYVEAVNELRVYKSQLEQI-ESEILSAKEEYQLVTQLFKNEILDKLR 305 Query: 136 KTVDQQTQLEERVSIIAQR 154 +T D L ++ +R Sbjct: 306 QTTDNIGLLTLELAKNEER 324
>CABNDNGRPT#NodO calcium binding signature. Length = 479 Score = 84.6 bits (209), Expect = 1e-18 Identities = 41/169 (24%), Positives = 61/169 (36%), Gaps = 17/169 (10%) Query: 1880 TIVGTDNINNLIFGSTNSDSLTGAN-LDDRIFGREDNDILIGLSGNDELIGGSGNDNVQG 1938 G +N+ + + G + N + + IGGSGND + G Sbjct: 295 VWDAGGTDTFDFSGYSNNQRINLNEGSFSDVGGLKGNVSIAHGVTIENAIGGSGNDILVG 354 Query: 1939 GEGNDFVIGGIGDDTLNGGIGRDYLSGGQGNDSLDGGALNGSDDGERDFFVWESDSADGS 1998 ++ + GG G+D L GG G D L GG G D+ G+ DS + Sbjct: 355 NSADNILQGGAGNDVLYGGAGADTLYGGAGRDTFVYGS--------------GQDSTVAA 400 Query: 1999 TDTVLNFNLDIDVLDLSDLLIGEESGNLEDFLSFSFSGGNTTITIDADG 2047 D + +F ID +DLS E F+ G + DA Sbjct: 401 YDWIADFQKGIDKIDLSAF--RNEGQLSFVQDQFTGKGQEVMLQWDAAN 447 Score = 67.3 bits (164), Expect = 3e-13 Identities = 33/159 (20%), Positives = 49/159 (30%), Gaps = 43/159 (27%) Query: 1875 ADDSITIVGTDNINNLIFGSTNSDSLTGANLDDRIFGREDNDILIGLSGNDELIGGSGND 1934 ++ I + + + G + S+ + G NDIL+G S ++ L GG+GND Sbjct: 309 YSNNQRINLNEGSFSDVGGLKGNVSIAHGVTIENAIGGSGNDILVGNSADNILQGGAGND 368 Query: 1935 NVQGGEGNDFVIGGIGDDTLNGGIG-----------RDYLSGGQGNDSLDGGALNG---- 1979 + GG G D + GG G DT G G D+ G D Sbjct: 369 VLYGGAGADTLYGGAGRDTFVYGSGQDSTVAAYDWIADFQKGIDKIDLSAFRNEGQLSFV 428 Query: 1980 ----------------------------SDDGERDFFVW 1990 + DF V Sbjct: 429 QDQFTGKGQEVMLQWDAANSITNLWLHEAGHSSVDFLVR 467 Score = 33.4 bits (76), Expect = 0.012 Identities = 11/70 (15%), Positives = 19/70 (27%), Gaps = 4/70 (5%) Query: 1922 SGNDELIGGSGNDNVQGGE----GNDFVIGGIGDDTLNGGIGRDYLSGGQGNDSLDGGAL 1977 N G D++ + N G N RD+ + + +L Sbjct: 237 DYNGHYGGAPMIDDIAAIQRLYGANMTTRTGDSVYGFNSNTDRDFYTATDSSKALIFSVW 296 Query: 1978 NGSDDGERDF 1987 + DF Sbjct: 297 DAGGTDTFDF 306
>CABNDNGRPT#NodO calcium binding signature. Length = 479 Score = 66.5 bits (162), Expect = 1e-12 Identities = 52/206 (25%), Positives = 73/206 (35%), Gaps = 22/206 (10%) Query: 3789 GDDKVNAGEGNDIIFGDLVSFDGIDGQGFSALQAFVAQETNQQPTNVTVQDIHEFISSNT 3848 D A + + + + G D FS + N + N Sbjct: 278 DRDFYTATDSSKALIFSVWDAGGTDTFDFSG-----YSNNQRINLNEGSFSDVGGLKGNV 332 Query: 3849 HLFGESNTDDGADTLEGGEGNDILFGQGGNDELIGGLGADTLIGGLGDDKLTGNEGADTF 3908 + + GG GNDIL G ++ L GG G D L GG G D L G G DTF Sbjct: 333 SIAH----GVTIENAIGGSGNDILVGNSADNILQGGAGNDVLYGGAGADTLYGGAGRDTF 388 Query: 3909 VWDRNSIDNSDPTDRNTDHITDFNMAEDKLDLSDILQGDTVSELAQH---------LSFT 3959 V+ D T D I DF DK+DLS +S + L + Sbjct: 389 VYG----SGQDSTVAAYDWIADFQKGIDKIDLSAFRNEGQLSFVQDQFTGKGQEVMLQWD 444 Query: 3960 DENGSTSINIDTDGNGSFDQHIVLDG 3985 N T++ + G+ S D + + G Sbjct: 445 AANSITNLWLHEAGHSSVDFLVRIVG 470
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 30.3 bits (68), Expect = 0.011 Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 9/69 (13%) Query: 278 YGESHQLRKSKGVTAGVRYDVTSSISLNLEYQMIFSQEEGNRAQFVTSPLVYDESSDVDL 337 YG++H S GV Y +T I+ LEYQ ++ G+ T P D + Sbjct: 132 YGKNHDTGVSPVFAGGVEYAITPEIATRLEYQ--WTNNIGDAHTIGTRP-------DNGM 182 Query: 338 VTLSVNFVF 346 ++L V++ F Sbjct: 183 LSLGVSYRF 191
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 67.9 bits (166), Expect = 8e-14 Identities = 28/111 (25%), Positives = 55/111 (49%), Gaps = 8/111 (7%) Query: 759 RIVILIVEDNLVNQKVASLLVKQAGFDCIIANNGQEALDFISSGEAFHAILMDCMMPVMD 818 IL+ +D+ + V + + +AG+D I +N +I++G+ ++ D +MP + Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGD-GDLVVTDVVMPDEN 61 Query: 819 GFTATEKIREWEGLHSQSRLPIIALTA-SVLDQDIKRCYQSGMDDYLAKPF 868 F +I++ + LP++ ++A + IK + G DYL KPF Sbjct: 62 AFDLLPRIKKA-----RPDLPVLVMSAQNTFMTAIK-ASEKGAYDYLPKPF 106
>adhesinb#Adhesin B signature. Length = 310 Score = 34.1 bits (78), Expect = 0.002 Identities = 28/126 (22%), Positives = 45/126 (35%), Gaps = 18/126 (14%) Query: 219 ETATNVHGIKFINQARDKGAKLLV-----VNPMRTPIASQAD-----VWLQPKPSTDTYL 268 ET N K + A+ K K V+ + S+ WL + Sbjct: 94 ETGGNAWFTKLVENAKKKENKDYYAVSEGVDVIYLEGQSEKGKEDPHAWLNLENGI--IY 151 Query: 269 ATGIMKYLVENDLADMKFIEANTLDYQDLLKRLDEMSYDEIEQVTGVPREKMFE------ 322 A I K L E D A+ + E N Y + L LD+ + ++ + G + + Sbjct: 152 AQNIAKRLSEKDPANKETYEKNLKAYVEKLSALDKEAKEKFNNIPGEKKMIVTSEGCFKY 211 Query: 323 FAKVYG 328 F+K Y Sbjct: 212 FSKAYN 217
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 59.4 bits (144), Expect = 4e-12 Identities = 51/321 (15%), Positives = 120/321 (37%), Gaps = 29/321 (9%) Query: 49 SQVSLYGSLRPSLSYLDD---NQDKTWDVR------DALSRIGIKASTEFADGWSAIAQG 99 + V+LYG+++ + N + V D S+IG K + +G AI Q Sbjct: 19 ADVTLYGTIKAGVETSRSVAHNGAQAASVETGTGIVDLGSKIGFKGQEDLGNGLKAIWQV 78 Query: 100 EWSVDIANSGNFGKARQAYAAIASPYGQVGIGKQRPAQYTLVAEYVDIFNNANSPFGYDH 159 E IA + + RQ++ + +G++ +G+ ++ +++ + G + Sbjct: 79 EQKASIAGTDSGWGNRQSFIGLKGGFGKLRVGRLNSVLKD--TGDINPWDSKSDYLGVN- 135 Query: 160 ESPFFVDNF---VTYQLVTGDFTWMAGA---QFNGDSGEDATDMVNVGVGYDLNQLHIGL 213 + V Y + +F ++G+ N ++G ++ + G Y + Sbjct: 136 -KIAEPEARLISVRYD--SPEFAGLSGSVQYALNDNAGRHNSESYHAGFNYKNGGFFVQY 192 Query: 214 GYVSQNTVD-NQHIEGDDNTLGGVVAYTFSNDLYLAVSYQDKQYNYDAGSMNKDRSGSTL 272 G + +++ + + +V+ ++ LY +V+ Q Q + N + T Sbjct: 193 GGAYKRHHQVQENVNIEKYQIHRLVSGYDNDALYASVAVQ--QQDAKLVEENYSHNSQTE 250 Query: 273 DTALAYPIFDDYKVKLGYFQFK----DGIDDNTSADYDGFNTTLEWNPVDNVRVHLEYLD 328 A F + ++ Y D + N D +++ + V +L Sbjct: 251 VAATLAYRFGNVTPRVSYAHGFKGSFDATNYNNDYDQVVVGAEYDFSKRTSALVSAGWLQ 310 Query: 329 KN-FDNRDDDRSITIGFRYDF 348 + +++ + +G R+ F Sbjct: 311 EGKGESKFVSTAGGVGLRHKF 331
>SSPAMPROTEIN#Salmonella surface presentation of antigen gene type M signature. Length = 147 Score = 27.3 bits (60), Expect = 0.014 Identities = 21/72 (29%), Positives = 36/72 (50%) Query: 39 LRCMSGDISQQEFFDEQRKLSSMVWQIKDLEAKIEQFNQTQGVKRGQLSDSEKNQIYHYY 98 LR + +S++E + RK S + QIKDLE +I Q + + + + ++ Y Sbjct: 56 LRAENRQLSREEIYALLRKQSIVRRQIKDLELQIIQIQEKRSELEKKREEFQEKSKYWLR 115 Query: 99 KTGNYTQMQLSQ 110 K GNY + + Q Sbjct: 116 KEGNYQRWIIRQ 127
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 26.8 bits (59), Expect = 0.011 Identities = 16/58 (27%), Positives = 27/58 (46%), Gaps = 6/58 (10%) Query: 1 MKSTKTAVGVTVAGILAASLSLGAQAVPEQPKEWEKCAGVAKAGANDCGALDGSHGCA 58 MK KTA+ + VA A++ AQA P + W A + + +D G ++ + Sbjct: 1 MK--KTAIAIAVALAGFATV---AQAAP-KDNTWYTGAKLGWSQYHDTGFINNNGPTH 52
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 63.4 bits (154), Expect = 2e-13 Identities = 45/174 (25%), Positives = 63/174 (36%), Gaps = 19/174 (10%) Query: 126 ALEQGYTWQVNIQAADTSGYQISSSPVSTRLVAN-----QFRLCRQQLLPKPFTYLRRIE 180 A Y W NI A T G + + +S + + P P + Sbjct: 157 ATRLEYQWTNNIGDAHTIGTRPDNGMLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKHFT 216 Query: 181 L----LFAPSSSLLNNSHEQDLYAVYRYL-QADSSIVEILVDGHADASGDHLANLVLSKE 235 L LF + + L + L +Y L D ++V G+ D G N LS+ Sbjct: 217 LKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSER 276 Query: 236 RADEVVSRLIELGVSAKMIQTRHHGTRAPVASN--NNTEGREL-------NRRV 280 RA VV LI G+ A I R G PV N +N + R +RRV Sbjct: 277 RAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRV 330
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 380 bits (978), Expect = e-131 Identities = 141/401 (35%), Positives = 211/401 (52%), Gaps = 47/401 (11%) Query: 74 ELASIAMQCGVQDYLLLPIDEEQLCSLLQR--------LRRLELPNNE---LICAAPVSR 122 A A + G DYL P D +L ++ R +LE + + L+ + + Sbjct: 88 MTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQ 147 Query: 123 QLLMLAHRAANTEATVLLTGESGTGKEPLARYIHRHSNRTDKPFIAINCAAIPESILESI 182 ++ + R T+ T+++TGESGTGKE +AR +H + R + PF+AIN AAIP ++ES Sbjct: 148 EIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESE 207 Query: 183 LFGHVKGAFTGATTDQIGKFELANGGTLLLDEIGEMPLLLQAKLLRVLQEREVERLGSHK 242 LFGH KGAFTGA T G+FE A GGTL LDEIG+MP+ Q +LLRVLQ+ E +G Sbjct: 208 LFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRT 267 Query: 243 SITLDIRVIAATNKDLRQAVQDGKFREDLFYRLDVLPIKILPLRQRKEDILPIAEHFLQR 302 I D+R++AATNKDL+Q++ G FREDL+YRL+V+P+++ PLR R EDI + HF+Q+ Sbjct: 268 PIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQ 327 Query: 303 YKILAANQQCYFSEQARNLLLSHDWPGNVRELENTIQRALVMRRGQALQAEELGL----- 357 + + + F ++A L+ +H WPGNVRELEN ++R + + E + Sbjct: 328 AEKEGLDVKR-FDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSE 386 Query: 358 -------------VNQDGSALVEQNELG--------------LKASKRQAEFQYIIDTLK 390 + S VE+N + E+ I+ L Sbjct: 387 IPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALT 446 Query: 391 RYNGHRNNTAQALGMTTRALRYKLVQMREEGIDIDQILSQS 431 G++ A LG+ LR K +RE G+ + + + Sbjct: 447 ATRGNQIKAADLLGLNRNTLRKK---IRELGVSVYRSSRSA 484
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 48.9 bits (116), Expect = 6e-11 Identities = 21/72 (29%), Positives = 34/72 (47%), Gaps = 1/72 (1%) Query: 42 SFTELMKHKVSSINADQNASSALVAAVDSGQSD-DLVGAMVASQKSSLAFSAMIQIRNRL 100 SF + + I+ Q A+ G+ L M QK+S++ IQ+RN+L Sbjct: 32 SFAGQLHAALDRISDTQTAARTQAEKFTLGEPGVALNDVMTDMQKASVSMQMGIQVRNKL 91 Query: 101 VQAFDDVMKMPI 112 V A+ +VM M + Sbjct: 92 VAAYQEVMSMQV 103
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 315 bits (809), Expect = e-103 Identities = 172/597 (28%), Positives = 275/597 (46%), Gaps = 82/597 (13%) Query: 2 STTLTQTSPVMTDVNGNNDRLNSLKQKWHQFSRGDRHAATLAILAIVAACVIVLMLWSTG 61 ++T TQ P+ + LN L+ + + A V+ ++LW+ Sbjct: 4 ASTATQPKPL--------EWLNRLRAN--------PRIPLIVAGSAAVAIVVAMVLWAKT 47 Query: 62 QGYSPLYGNQENVETSHIIEVLEAEGISYRLDPTSGLILVPEDRVGNARMVLAARGVKAK 121 Y L+ N + + I+ L I YR SG I VP D+V R+ LA +G+ Sbjct: 48 PDYRTLFSNLSDQDGGAIVAQLTQMNIPYRFANGSGAIEVPADKVHELRLRLAQQGLPKG 107 Query: 122 VPSGMESLDSSAIGTSQFMEQAKYRYSLEGELSRTIMALKSVKTARVHLAIPKKTLFIRQ 181 G E LD G SQF EQ Y+ +LEGEL+RTI L VK+ARVHLA+PK +LF+R+ Sbjct: 108 GAVGFELLDQEKFGISQFSEQVNYQRALEGELARTIETLGPVKSARVHLAMPKPSLFVRE 167 Query: 182 QPELPSASVMLDLYAGQHLQPEQITSIANLVAGSVTGMTPERVQIVDQEGNHLSSEINAN 241 Q + PSASV + L G+ L QI+++ +LV+ +V G+ P V +VDQ G+ L+ + Sbjct: 168 Q-KSPSASVTVTLEPGRALDEGQISAVVHLVSSAVAGLPPGNVTLVDQSGHLLTQSNTSG 226 Query: 242 QDLTQARDKQLQYTQELEQSLINRASSMLQPILGQDNFQVQVAALVNFNQVEETRESLDP 301 +DL D QL++ ++E + R ++L PI+G N QV A ++F E+T E P Sbjct: 227 RDLN---DAQLKFANDVESRIQRRIEAILSPIVGNGNVHAQVTAQLDFANKEQTEEHYSP 283 Query: 302 Q------TVVSQEKQSTNQTSGDMALGIPGALSNQPPTADAATNNSTSNLNQ-------- 347 T+ S++ + Q G+PGALSNQP + A + Q Sbjct: 284 NGDASKATLRSRQLNISEQVGAGYPGGVPGALSNQPAPPNEAPIATPPTNQQNAQNTPQT 343 Query: 348 ----------------QESRQFEVGRSVKHTRYQQMQLENLSISVLLNNQ---AAGETGW 388 E+ +EV R+++HT+ +E LS++V++N + Sbjct: 344 STSTNSNSAGPRSTQRNETSNYEVDRTIRHTKMNVGDIERLSVAVVVNYKTLADGKPLPL 403 Query: 389 TQPQLDQMSTMVQDAIGYSAARGDQFSISSFNFAPVKIAEFEPLPWWQGESYQAYLRYFI 448 T Q+ Q+ + ++A+G+S RGD ++ + F+ V E LP+WQ +S+ L Sbjct: 404 TADQMKQIEDLTREAMGFSDKRGDTLNVVNSPFSAVDNTGGE-LPFWQQQSFIDQLLAAG 462 Query: 449 GAILGLGMIF----FVLRPLVQHLTRTVEHNIKDTLPSTQPLMPPAEAATAHLSQDAAQE 504 +L L + + +RP LTR VE A+ + +E Sbjct: 463 RWLLVLVVAWILWRKAVRPQ---LTRRVEE------------AKAAQEQAQ--VRQETEE 505 Query: 505 AADNLVALNNANINSNWTSNLNLPAPGSPLTVQMEHLSLLANQEPARVAEVISHWIS 561 A + L+ +N L A V + + +++ +P VA VI W+S Sbjct: 506 AVEV--RLSKDEQLQQRRANQRLGA-----EVMSQRIREMSDNDPRVVALVIRQWMS 555
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 178 bits (453), Expect = 1e-55 Identities = 82/324 (25%), Positives = 169/324 (52%), Gaps = 1/324 (0%) Query: 5 EQAAMLLLSMGEKGAAQVMAHLDRNDVQHLSHKMARLSSITQQEAEAVLGRFFTRYQEQS 64 ++AA+LL+S+G + +++V +L + +++ L+ ++A+L +IT + + VL F Q Sbjct: 19 QKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKLETITSELKDNVLLEFKELMMAQE 78 Query: 65 GIARASRTYLQKTLDLALGDRVAKSLIDSIYGDEIKVLVKRLEWVDPQLLAREIANEHCQ 124 I + Y ++ L+ +LG + A +I+++ + + DP + I EH Q Sbjct: 79 FIQKGGIDYARELLEKSLGTQKAVDIINNLGSALQSRPFEFVRRADPANILNFIQQEHPQ 138 Query: 125 LQAVLLGLLPPESAAQVLQGLPAEGQDEVLIRIAQLGDLDREVVDELKQLVERCMLMAME 184 A++L L P+ A+ +L LP E Q V RIA + EVV E+++++E+ + Sbjct: 139 TIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVVREVERVLEKKLASLSS 198 Query: 185 KSHTQISGVRQVADILNRFD-GDREQLMEMLKLHDKQLANNVADNMFDFIILGRQKPETL 243 + +T GV V +I+N D + ++E L+ D +LA + MF F + ++ Sbjct: 199 EDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPELAEEIKKKMFVFEDIVLLDDRSI 258 Query: 244 QEIMAIVPADVLALALKGIDSELKMTLLRALPKRMSSAIETQVEAIGTVPLSQAIAARKE 303 Q ++ + LA ALK +D ++ + + + KR +S ++ +E +G ++++ Sbjct: 259 QRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRAASMLKEDMEFLGPTRRKDVEESQQK 318 Query: 304 IMELAKQMMDEGQIELQLFEEQVV 327 I+ L +++ ++G+I + E+ V Sbjct: 319 IVSLIRKLEEQGEIVISRGGEEDV 342
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 59.8 bits (144), Expect = 6e-13 Identities = 41/182 (22%), Positives = 85/182 (46%), Gaps = 2/182 (1%) Query: 42 QDFQQAFDKGYDEGVQKGHQAGFTSGEEEGRQTGYAAGFNQGRIEGQQKGKDNIDDQLNS 101 ++ + + ++ + + H+ G+ +G EGRQ G+ G+ +G +G ++G Q Sbjct: 34 EEAEPSLEQQLAQLQMQAHEQGYQAGIAEGRQQGHKQGYQEGLAQGLEQGLAEAKSQQAP 93 Query: 102 IIAPLGALKSLLEEGHNQQILQQQSLILDLVRRVSLQVIRCELTLQPQQILSLIEETLSA 161 I A + L S + + S ++ + + QVI T+ ++ I++ L Sbjct: 94 IHARMQQLVSEFQTTLDALDSVIASRLMQMALEAARQVIGQTPTVDNSALIKQIQQLLQQ 153 Query: 162 LPDDPSQVKIHLEPSAVDKLKEL--AADKIQSWSLVPDATISAGGCRIVSETSDADASVE 219 P + ++ + P + ++ ++ A + W L D T+ GGC++ ++ D DASV Sbjct: 154 EPLFSGKPQLRVHPDDLQRVDDMLGATLSLHGWRLRGDPTLHPGGCKVSADEGDLDASVA 213 Query: 220 TR 221 TR Sbjct: 214 TR 215
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 33.0 bits (75), Expect = 3e-04 Identities = 8/39 (20%), Positives = 19/39 (48%) Query: 98 SNVNTVEEMADMMAASRSFETNVEIMNRARSMQQGLLQL 136 S VN EE ++ + + N +++ A ++ L+ + Sbjct: 507 SGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545 Score = 27.2 bits (60), Expect = 0.021 Identities = 14/59 (23%), Positives = 25/59 (42%), Gaps = 4/59 (6%) Query: 9 IAGAGMNAQTIRLNTVASNLANAGAAAESPDEAFRALKPVFSTIYKQTQEGQVAGAHVE 67 A +G+NA LNT ++N+++ A + + ST+ G G +V Sbjct: 6 NAMSGLNAAQAALNTASNNISSYNVAGYTRQTTI--MAQANSTLGAGGWVGN--GVYVS 60
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 34.2 bits (78), Expect = 0.001 Identities = 15/41 (36%), Positives = 22/41 (53%) Query: 360 LEGSNVDQTAEMVNLMTAQRNYQSNAKVLDTNSTMQQALLN 400 S V+ E NL Q+ Y +NA+VL T + + AL+N Sbjct: 504 QSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALIN 544 Score = 34.2 bits (78), Expect = 0.001 Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 5/59 (8%) Query: 2 SFNIALSGLQATTQDLNTISNNIANSSTVGFRSGR----SEFSAIYNGGQAG-GVNVMN 55 N A+SGL A LNT SNNI++ + G+ S + GG G GV V Sbjct: 3 LINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVSG 61
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 42.3 bits (99), Expect = 1e-06 Identities = 11/47 (23%), Positives = 21/47 (44%) Query: 213 QIRQGALEGANVNVVEEMVEMISTQRAYEMNAKVVSASDDMLKFLNQ 259 Q+ + VN+ EE + Q+ Y NA+V+ ++ + L Sbjct: 498 QLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALIN 544 Score = 39.2 bits (91), Expect = 1e-05 Identities = 10/37 (27%), Positives = 19/37 (51%) Query: 3 SALWVSKTGLTAQDTKMTTIANNLANVNTTGFKRDRV 39 S + + +GL A + T +NN+++ N G+ R Sbjct: 2 SLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTT 38
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 148 bits (375), Expect = 1e-46 Identities = 76/224 (33%), Positives = 112/224 (50%), Gaps = 17/224 (7%) Query: 12 LTLLLSGCVAHIPEPDTAPGKPEWAPPEIDYSLPDAENGSVYRPGFMLT-----LFKDKR 66 L L L+GC A IP + P + NGS+++ + LF+D+R Sbjct: 15 LVLSLTGC-AWIP---STPLVQGATSAQPVPGPTPVANGSIFQSAQPINYGYQPLFEDRR 70 Query: 67 AYREGDILTVALDEKTYSSKRADTKTSKSGGVSIDGQGTTGTSSIAGSG------EANMG 120 GD LT+ L E +SK + S+ G + G T G EA+ G Sbjct: 71 PRNIGDTLTIVLQENVSASKSSSANASRDGKTNF-GFDTVPRYLQGLFGNARADVEASGG 129 Query: 121 RSFNGTGSSTQQNQLSGSITVTVAKVLPNGALLIRGEKWLRLNQGDEYLRLLGLIRADDI 180 +FNG G + N SG++TVTV +VL NG L + GEK + +NQG E++R G++ I Sbjct: 130 NTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRFSGVVNPRTI 189 Query: 181 DNDNTISSQRIADARIIYGGQGAISDSNRMGWAARYFNSPWFPL 224 NT+ S ++ADARI Y G G I+++ MGW R+F + P+ Sbjct: 190 SGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLN-LSPM 232
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 343 bits (880), Expect = e-118 Identities = 151/370 (40%), Positives = 211/370 (57%), Gaps = 14/370 (3%) Query: 11 MLLSLSPLLPVKAQPQHRYLMDIVDVQGLRDNQLVGYGLVVGLDGTGDRT-QVRFTSQSI 69 + +L L AQ + DI +Q RDNQL+GYGLVVGL GTGD FT QS+ Sbjct: 12 VFSALPFLSTPPAQADTSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFTEQSM 71 Query: 70 VNMLKQFGVQIDDKTDPKLKNVAAVAVHATVPPLASPGQTLDITVSSLGDAKSLRGGTLL 129 ML+ G+ KN+AAV V A +PP ASPG +D+TVSSLGDA SLRGG L+ Sbjct: 72 RAMLQNLGITTQG-GQSNAKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRGGNLI 130 Query: 130 MTPMRAVDGEIYAVAQGNLVVGGVSAQGRNGTSVTINVPTVGSIPNGALLEAAMHSNFND 189 MT + DG+IYAVAQG L+V G SAQG + ++T V T +PNGA++E + S F D Sbjct: 131 MTSLSGADGQIYAVAQGALIVNGFSAQG-DAATLTQGVTTSARVPNGAIIERELPSKFKD 189 Query: 190 NENIVLNLIDPSFKTARNIERAVNEL----FGPDVAQADSSAKVIVRAPSSNRERVTFMS 245 + N+VL L +P F TA + VN +G +A+ S ++ V+ P + M+ Sbjct: 190 SVNLVLQLRNPDFSTAVRVADVVNAFARARYGDPIAEPRDSQEIAVQKP-RVADLTRLMA 248 Query: 246 MLEELQIEQGRKSPRVVFNSRTGTVVMGGDVVVRKAAVSHGNLTVTIVEQEFVSQPNGAY 305 +E L +E +VV N RTGT+V+G DV + + AVS+G LTV + E V QP Sbjct: 249 EIENLTVETDTP-AKVVINERTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQPAPF- 306 Query: 306 LGQAQGETVVTTDSQVGIDEGNGHMFVWPEGTALNDIVRAVNSLGASPMDLMAILQALNE 365 ++G+T V + + + + + EG L +V +NS+G ++AILQ + Sbjct: 307 ---SRGQTAVQPQTDIMAMQEGSKVAI-VEGPDLRTLVAGLNSIGLKADGIIAILQGIKS 362 Query: 366 AGALEAELVV 375 AGAL+AELV+ Sbjct: 363 AGALQAELVL 372
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 50.1 bits (119), Expect = 3e-10 Identities = 27/96 (28%), Positives = 48/96 (50%), Gaps = 5/96 (5%) Query: 26 GALKLVSQQFEAQFLQTVLKQMRSASDVMADKDSPLSSQNDGMYRDWHDAELAGRLSQMQ 85 ++ V++Q E F+Q +LK MR A KD SS++ +Y +D ++A +++ + Sbjct: 31 ANIRPVARQVEGMFVQMMLKSMRDALP----KDGLFSSEHTRLYTSMYDQQIAQQMTAGK 86 Query: 86 STGLAEVMTKQLSAGLKSEPEMVASNKQVNSSPNTA 121 GLAE+M KQ++ + PE + T Sbjct: 87 GLGLAEMMVKQMTPE-QPLPEESTPAAPMKFPLETV 121
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 168 bits (427), Expect = 1e-48 Identities = 95/320 (29%), Positives = 156/320 (48%), Gaps = 8/320 (2%) Query: 2 SMLNIGMSGLNASMAALTATSNNINNAMVPGYSRQQVMLSSVGNGVYGS---GSGVMVDG 58 S++N MSGLNA+ AAL SNNI++ V GY+RQ +++ + + G+GV V G Sbjct: 2 SLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVSG 61 Query: 59 VRRISDQYEVAQLWNTTSGLGYANTQSSYFGQVEQIFGSEGNSISAGLDLLFASLNSAME 118 V+R D + QL + + +++ + + +S++ + F SL + + Sbjct: 62 VQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLVS 121 Query: 119 QPNEIAHRQGVLNEAKALTQRFNSISEGLNSQVTQVEGQINASAKEINTQLETIASLNAE 178 + A RQ ++ +++ L +F + + L Q QV I AS +IN + IASLN + Sbjct: 122 NAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLNDQ 181 Query: 179 IQSS--NASGNVPLALLDARDSAIDDLSSIIDVNVVEDSSGMLNISLAQGQPLLSGTTAS 236 I +G P LLD RD + +L+ I+ V V G NI++A G L+ G+TA Sbjct: 182 ISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTAR 241 Query: 237 KLEV---TPDPSNPKFSQISIQFGQSSFPLDETAGGSLGALIDYRDNSLVDSMAFIDELA 293 +L + DPS + + G P GSLG ++ +R L + + +LA Sbjct: 242 QLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQLA 301 Query: 294 MTMADEFNAVLAGGTDLNGN 313 + A+ FN G D NG+ Sbjct: 302 LAFAEAFNTQHKAGFDANGD 321 Score = 73.1 bits (179), Expect = 6e-16 Identities = 36/105 (34%), Positives = 60/105 (57%), Gaps = 3/105 (2%) Query: 351 GDNSNLKELVDIANKSFTFSSMGVDTTMGDAFGSKIGELGSASRQAQMSKTTAENLQMEA 410 DN N + L+D+ + S ++G + DA+ S + ++G+ + + S T N+ + Sbjct: 443 SDNRNGQALLDLQSNS---KTVGGAKSFNDAYASLVSDIGNKTATLKTSSATQGNVVTQL 499 Query: 411 QKQWASTSGVNMDEEGVNLIIYQQSYQANAKVISTADQLFQTILN 455 Q S SGVN+DEE NL +QQ Y ANA+V+ TA+ +F ++N Sbjct: 500 SNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALIN 544
>FLAGELLIN#Flagellin signature. Length = 507 Score = 45.4 bits (107), Expect = 1e-07 Identities = 28/143 (19%), Positives = 53/143 (37%) Query: 11 NNLQSLQNSTFDIAKLNEMMSTGSSILRPSDDPIGAVKVIGNERDMAATNQYIKNTESLS 70 +L S ++ E +S+G I DD G ++ Q +N Sbjct: 12 LTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQASRNANDGI 71 Query: 71 TSFSRSETYMSSMVELQGRMREITVSANNGSLSPEDRAAYAAEMNELLEAFADTLNAKDE 130 + +E ++ + R+RE++V A NG+ S D + E+ + LE N Sbjct: 72 SIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEEIDRVSNQTQF 131 Query: 131 SGNYLFSGNKTDTPPIGKDADGN 153 +G + S + +G + Sbjct: 132 NGVKVLSQDNQMKIQVGANDGET 154
>FLAGELLIN#Flagellin signature. Length = 507 Score = 97.8 bits (243), Expect = 3e-25 Identities = 74/269 (27%), Positives = 125/269 (46%), Gaps = 9/269 (3%) Query: 4 VMTNNASNIAQNAVTKNNDLLSNAMERLSTGLRINSASDDAAGLQIATRLNANVTGMETA 63 + TN+ S + QN + K+ LS+A+ERLS+GLRINSA DDAAG IA R +N+ G+ A Sbjct: 4 INTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQA 63 Query: 64 NRNVSDATSMLQTADGALDELNNIASRQKELATQAANGVNSAEDIKALGAEYKELNAEAN 123 +RN +D S+ QT +GAL+E+NN R +EL+ QA NG NS D+K++ E ++ E + Sbjct: 64 SRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEEID 123 Query: 124 RIIDSTEYGGNKLFTALDTGVGFQIGASNTASEQLTVKTDVAAVKTLFAGE--------I 175 R+ + T++ G K+ + D + Q+GA++ + + ++ L + Sbjct: 124 RVSNQTQFNGVKVLSQ-DNQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKEATV 182 Query: 176 TDSATAKAQIDNVDAIIDAVGTQRSNLGASINRLGHTASNLTNVTENTKAAAGRIMDTDF 235 D ++ + D R ++ + TA + + A D Sbjct: 183 GDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTDDAE 242 Query: 236 AVETAAMTKNQLLVQAGTNILSSSNQNTG 264 + K + + G Sbjct: 243 NNTAVDLFKTTKSTAGTAEAKAIAGAIKG 271 Score = 65.8 bits (160), Expect = 2e-14 Identities = 50/266 (18%), Positives = 83/266 (31%) Query: 5 MTNNASNIAQNAVTKNNDLLSNAMERLSTGLRINSASDDAAGLQIATRLNANVTGMETAN 64 NN + + + D G+ G + Sbjct: 241 AENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGNGKVS 300 Query: 65 RNVSDATSMLQTADGALDELNNIASRQKELATQAANGVNSAEDIKALGAEYKELNAEANR 124 ++ L AD N A+ + + VN ++ Sbjct: 301 TTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSDLEA 360 Query: 125 IIDSTEYGGNKLFTALDTGVGFQIGASNTASEQLTVKTDVAAVKTLFAGEITDSATAKAQ 184 + A T + KT + + Sbjct: 361 NNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINEDAAAAKKSTANP 420 Query: 185 IDNVDAIIDAVGTQRSNLGASINRLGHTASNLTNVTENTKAAAGRIMDTDFAVETAAMTK 244 + ++D+ + V RS+LGA NR +NL N N +A RI D D+A E + M+K Sbjct: 421 LASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYATEVSNMSK 480 Query: 245 NQLLVQAGTNILSSSNQNTGLVMGLL 270 Q+L QAGT++L+ +NQ V+ LL Sbjct: 481 AQILQQAGTSVLAQANQVPQNVLSLL 506
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 46.8 bits (110), Expect = 8e-08 Identities = 36/129 (27%), Positives = 56/129 (43%) Query: 232 AVAQWGPVSVSQSAPLPQQSHEMLSPLREQLRFQIDQQIKQAELRLDPPELGKIELNVRL 291 Q P + P SHE L + + Q + AELRL P +LG++++++++ Sbjct: 218 HQTQPLPTVAAPVLSAPLGSHEWQQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLKV 277 Query: 292 DGDRLHIQMHAANSSVRDALLMGLDRLRAELAMDHGGQIDVDISQGEPQQKQHQGRSQSA 351 D ++ IQM + + VR AL L LR +LA +IS +Q Q Sbjct: 278 DDNQAQIQMVSPHQHVRAALEAALPVLRTQLAESGIQLGQSNISGESFSGQQQAASQQQQ 337 Query: 352 IAAANLHEP 360 HEP Sbjct: 338 SQRTANHEP 346
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 36.4 bits (84), Expect = 1e-04 Identities = 32/132 (24%), Positives = 50/132 (37%), Gaps = 24/132 (18%) Query: 186 FTRGSADMKPYFEDLLMALGPLLSQVE---NKITISGHTDSSPYAGKKFTNWELSSKRAL 242 F A +KP + L L LS ++ + + G+TD G N LS +RA Sbjct: 223 FNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRI---GSDAYNQGLSERRAQ 279 Query: 243 LARRVLEYGGLRRHQVIQVTGM------ADQAPYVIKDPAA-----AANRRIEVLVMTSD 291 L G+ + I GM +K AA A +RR+E+ V Sbjct: 280 SVVDYLISKGIPADK-ISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEV---- 334 Query: 292 AENQLRQMMGQP 303 ++ ++ QP Sbjct: 335 --KGIKDVVTQP 344
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 29.8 bits (67), Expect = 0.048 Identities = 23/105 (21%), Positives = 44/105 (41%), Gaps = 17/105 (16%) Query: 338 LLIGLASLFALLLTSFAFNMIGYLGEELLPRLDALSLNANMLLFAVLVTLVIAFVFSWIE 397 IGL++ A+L+ FA ++ + +E ++A + M L +L+T +AF+ + Sbjct: 932 TTIGLSAKNAILIVEFAKDL---MEKEGKGVVEATLMAVRMRLRPILMT-SLAFILGVLP 987 Query: 398 LKAIDESQLQSCLQASGKGTGKQLSKGVSHGLIGLQLLFAVLTLV 442 L A G G V G++G + +L + Sbjct: 988 L-------------AISNGAGSGAQNAVGIGVMGGMVSATLLAIF 1019
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 36.7 bits (85), Expect = 1e-04 Identities = 57/389 (14%), Positives = 115/389 (29%), Gaps = 93/389 (23%) Query: 49 GEFTQRIRGYGTLM-SQNQRLITASSLAVVDEIKLHPGAEVSANSILLILKNPQLDSALQ 107 G+ G L S + I ++V EI + G V +LL L ++ Sbjct: 78 GQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTL 137 Query: 108 QAETNVHNSRTTKRKL------------------------------------MLEQQREL 131 + ++++ +R + + ++++Q Sbjct: 138 KTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFST 197 Query: 132 LDQASSLAEFKADAEIANLQVEAESPLAAEGIISAMDMRLSRLRA-------------KQ 178 E D + A E + RL + +Q Sbjct: 198 WQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQ 257 Query: 179 LNERLKLGQD---KLGKLREVHAEHLLIQTEII-------KQAESELATAQNRREQL--- 225 N+ ++ + +L ++ +E L + E + +L + L Sbjct: 258 ENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLE 317 Query: 226 -----------VVRAGIEGVLQRLPIK-LGQSVNVGDEL-ALVGSLSPLIAEIKVPQMLI 272 V+RA + +Q+L + G V + L +V L V I Sbjct: 318 LAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDI 377 Query: 273 QLVRHGAKADID------TRSGIVSGQVIRVDP---------VVSQGAVRVDIQLL--DE 315 + G A I TR G + G+V ++ +V + ++ L Sbjct: 378 GFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCLSTGN 437 Query: 316 ISSDIRPMQMVDAVIFGKSRAQVNYVDKP 344 + + V A I R+ ++Y+ P Sbjct: 438 KNIPLSSGMAVTAEIKTGMRSVISYLLSP 466
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 29.1 bits (65), Expect = 0.040 Identities = 45/228 (19%), Positives = 77/228 (33%), Gaps = 42/228 (18%) Query: 129 GDRVIKLNKQRVTAEKLESILNE------IKQHSLDNQPIELEMVRANSDVHYSVTISPS 182 DR I V A + +IL I+Q ++DNQ I RA++ V PS Sbjct: 195 SDRTIHYRDDEVAAPGVATILQRVLSDATIQQVTVDNQRIPQAATRASAQA--RVEADPS 252 Query: 183 LIAINSVEAEILDNQIGYIRLSSFQENTTQELVKQLSAWQSE-KLNGIILDLRNNPGGLL 241 L AI +R S + Q L+ L + ++ I+D+ N L Sbjct: 253 LNAI-------------IVRDSPERMPMYQRLIHALDKPSARIEVALSIVDI--NADQLT 297 Query: 242 DQAIT-VADIFLDKGRIVATEGRFFDANSDYYASPQTMATNIPLSVLINKGSASASEVLA 300 + + I V + +N +A+N L L++ Sbjct: 298 ELGVDWRVGIRTGNNHQVVIKTTGDQSN---------IASNGALGSLVDARGLDYLLARV 348 Query: 301 AALQENGRAKLIGQTSFGKGTIQSLIPTLMDGNAIKLTIAKYTTPNGK 348 L+ G A+++ + + Q ++D + Y GK Sbjct: 349 NLLENEGSAQVVSRPTL---LTQENAQAVIDHSET-----YYVKVTGK 388
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 40.2 bits (94), Expect = 1e-05 Identities = 31/226 (13%), Positives = 82/226 (36%), Gaps = 14/226 (6%) Query: 13 AGFLSLPLTVNATDLERRQSELKSIQVQINKQQSAVKNTSKQRERLVSLLKDDEKAIAQA 72 G + L LT + + +++ +Q ++ + + + + S + +L L DE Sbjct: 120 KGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNV 179 Query: 73 ARKVNTTKQALAKTDKKIAELDRKHVQLDKLKKAQQKSLSNQLASAYLAGNHDYTKMLLN 132 + + +L K + + +L+ KK ++ + Y Sbjct: 180 SEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRY------------- 226 Query: 133 QQSPASIERLLAYYQYLNNARIDSINQLQTTLKELDQIQADQQEQQNRLNQLVLEQQQQA 192 + + L + L + + + + + + + + + +++L Q+ E Sbjct: 227 ENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAK 286 Query: 193 KKLNQEQSQRQN-TLTQLQRTLNNSGAKLEQLQIEEASLKRVVEQA 237 ++ +N L +L++T +N G +L E + V +A Sbjct: 287 EEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRA 332
>PF05272#Virulence-associated E family protein Length = 892 Score = 32.0 bits (72), Expect = 0.004 Identities = 11/27 (40%), Positives = 15/27 (55%) Query: 26 CKAGEVLAVVGPSGGGKSTLLRMIAGL 52 CK + + G G GKSTL+ + GL Sbjct: 593 CKFDYSVVLEGTGGIGKSTLINTLVGL 619
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 81.4 bits (201), Expect = 4e-20 Identities = 27/122 (22%), Positives = 54/122 (44%) Query: 2 KILMVEDDATTIEYVVKGFVEQGHNIETATDGHQGLLLATSMKYDLIILDRMLPQLDGLK 61 IL+ +DDA + + G+++ ++ + DL++ D ++P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 LLAALRATGSQTPVLILSALSHVDERVKGLRAGGDDYMTKPFAFSELLVRAEKLMQRGES 121 LL ++ PVL++SA + +K G DY+ KPF +EL+ + + + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 LP 123 P Sbjct: 125 RP 126
>PF06580#Sensor histidine kinase Length = 349 Score = 29.8 bits (67), Expect = 0.024 Identities = 18/99 (18%), Positives = 38/99 (38%), Gaps = 27/99 (27%) Query: 356 LVDNAVKY----SGEGAEICIS----QNRNVISIQDNGPGIPEASREKVFERLVRLDPSR 407 LV+N +K+ +G +I + + +++ G + ++E Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE------------- 309 Query: 408 HHKGTGLGLSMVKAILSR---HNAKIALTDNQPGLKVII 443 TG GL V+ L A+I L++ Q + ++ Sbjct: 310 ---STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMV 345
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 225 bits (575), Expect = 8e-79 Identities = 79/155 (50%), Positives = 110/155 (70%) Query: 5 AIYPGTFDPVTNGHADLIERAANLFEHVIIGIAANPSKQPRFTLAERVELLKTVTAHLDN 64 AIYPG+FDP+T GH D+IER LF+ V + + NP+KQP F++ ER+E + AHL N Sbjct: 3 AIYPGSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPMFSVQERLEQIAKAIAHLPN 62 Query: 65 VEVVGFSGLLVDFAKEQNASVLVRGLRAVSDFEYEFQLANMNRRLSPDLESVFLTPAEEN 124 +V F GL V++A+++ A ++RGLR +SDFE E Q+AN N+ L+ DLE+VFLT + E Sbjct: 63 AQVDSFEGLTVNYARQRQAGAILRGLRVLSDFELELQMANTNKTLASDLETVFLTTSTEY 122 Query: 125 SFISSTLVKEVALHGGDVSQFVHAEVANALTKKAN 159 SF+SS+LVKEVA GG+V FV + VA AL + + Sbjct: 123 SFLSSSLVKEVARFGGNVEHFVPSHVAAALYDQFH 157
>PF06580#Sensor histidine kinase Length = 349 Score = 43.3 bits (102), Expect = 1e-06 Identities = 27/186 (14%), Positives = 61/186 (32%), Gaps = 42/186 (22%) Query: 251 IVNDIEDMDAIINQFISYIRQDQEGTRE----LEQINDLIQDVIQAESNREG-------S 299 I+ D ++ +R + L ++ +Q S + Sbjct: 186 ILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQ 245 Query: 300 IDSELVECPRIPMQGIAVKRVLSNLVENAYRYG------NGWVRINSQFNGQYVGFSVED 353 I+ +++ PM ++ LVEN ++G G + + + V VE+ Sbjct: 246 INPAIMDVQVPPM-------LVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVEN 298 Query: 354 NGPGIDEEQIPKLFQPFTQGDTARGSVGSGLGLA-IIKRIVDRHQGKVILT-NRSEGGLH 411 G + +G GL + +R+ + + + + +G ++ Sbjct: 299 TGSLALKNTKE----------------STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVN 342 Query: 412 AQVWLP 417 A V +P Sbjct: 343 AMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 99.1 bits (247), Expect = 4e-26 Identities = 39/130 (30%), Positives = 71/130 (54%), Gaps = 3/130 (2%) Query: 6 SKILVVDDDMRLRALLERYLMEQGYQVRSAANAEQMDRLLERENFHLLVLDLMLPGEDGL 65 + ILV DDD +R +L + L GY VR +NA + R + + L+V D+++P E+ Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 66 SICRRLRQMGNPIPIVMLTAKGDEVDRIIGLELGADDYLPKPFNPRELLARIKAVM---R 122 + R+++ +P+++++A+ + I E GA DYLPKPF+ EL+ I + + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 123 RQTPEVPGAP 132 R+ ++ Sbjct: 124 RRPSKLEDDS 133
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 30.5 bits (68), Expect = 0.030 Identities = 30/93 (32%), Positives = 39/93 (41%), Gaps = 4/93 (4%) Query: 352 TTIFPHAPQNQWDKSVRTLSNLVKMHKVELIAIGNGTASRETDKLAADLISQVKADLPTL 411 T I PQ +WDK V T ++L K V + I G R+ D L + K L L Sbjct: 502 TEIKKQIPQKEWDKVVNTPNSLEKQKGVTNLLIKYGI-ERKPDSTKGTLSNWQKQMLDRL 560 Query: 412 T---KIMVSEAGASVYSASELASEEFPDIDVSI 441 K G V +E +EEFP+ D I Sbjct: 561 NEAVKYTGYTGGDVVNHGTEQDNEEFPEKDNEI 593
>56KDTSANTIGN#Rickettsia 56kDa type-specific antigen protein signature. Length = 533 Score = 27.2 bits (60), Expect = 0.030 Identities = 17/73 (23%), Positives = 28/73 (38%), Gaps = 15/73 (20%) Query: 59 QNQAKLRESVQQKQQGQSQQQEQSGQEKQKQAA---------NLNLKQL------LSQRA 103 Q Q +QQ QQ+Q+ Q+ A + + QL L + A Sbjct: 329 QIHLNFVMPPQAQQQQGQGQQQQAQATAQEAVAAAAVRLLNGSDQIAQLYKDLVKLQRHA 388 Query: 104 PLKRSDIKLPGQQ 116 ++++ KL QQ Sbjct: 389 GIRKAMEKLAAQQ 401
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.0 bits (70), Expect = 0.013 Identities = 11/31 (35%), Positives = 16/31 (51%), Gaps = 1/31 (3%) Query: 39 KWDQQVEVLIIGSGFAGLAAAIEATRKGAKD 69 K + VL++ S AI+A+ KGA D Sbjct: 71 KARPDLPVLVM-SAQNTFMTAIKASEKGAYD 100
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 37.7 bits (87), Expect = 2e-05 Identities = 26/165 (15%), Positives = 49/165 (29%), Gaps = 7/165 (4%) Query: 3 NWQQRESYLTDIAERCLRGHKSFDLRRSHLVEASQISKGTIYNHFPTEADLVVAVATAHY 62 Q+ ++ D+A R + +A+ +++G IY HF ++DL + Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSE 67 Query: 63 RKRLERAA-IDDDLYQDYLTRFL-----MHHCWGLRDDLLYDRFIISRVMPNSELLAQVT 116 E D L+ + + II +A V Sbjct: 68 SNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQ 127 Query: 117 DDNRETFEQVYGEYVRWNNDLIKAIGVVEGFNRAELVANYLRGAL 161 R + Y + I+A + A +RG + Sbjct: 128 QAQRNLCLESYDRIEQTLKHCIEAKMLPADLM-TRRAAIIMRGYI 171
>PF06580#Sensor histidine kinase Length = 349 Score = 38.3 bits (89), Expect = 5e-05 Identities = 23/125 (18%), Positives = 48/125 (38%), Gaps = 16/125 (12%) Query: 282 EADQLEQMIAELLELSRVKLNANETKRNLELSETLSQVLDDADFEAQQ----QQKQLHID 337 + + +M+ L EL R L R + L++ L+ V D+ + + Q Sbjct: 189 DPTKAREMLTSLSELMRYSL-RYSNARQVSLADELTVV--DSYLQLASIQFEDRLQFENQ 245 Query: 338 IDESIVAPLYPR----PLCRAVENLLRNAI--RYANSQVSIQAIATASNIQIEIIDDGPG 391 I+ +I+ P L VEN +++ I ++ ++ + +E+ + G Sbjct: 246 INPAIMDVQVPPMLVQTL---VENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSL 302 Query: 392 IADET 396 T Sbjct: 303 ALKNT 307
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 98.0 bits (244), Expect = 9e-26 Identities = 40/146 (27%), Positives = 71/146 (48%), Gaps = 2/146 (1%) Query: 2 SRILLIDDDLGLSELLAQLLELEGFELTLAHDGQSGLDLAIEQQFDLILLDVMLPKLNGF 61 + IL+ DDD + +L Q L G+++ + + + DL++ DV++P N F Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 EVLRALRS-KKQTPVLMLTARGDEIDRVVGLEIGADDYLPKPFNDRELVARI-RAIIRRT 119 ++L ++ + PVL+++A+ + + E GA DYLPKPF+ EL+ I RA+ Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 120 HSQANETPLSTRQYGDINLDPARQEV 145 + S + A QE+ Sbjct: 124 RRPSKLEDDSQDGMPLVGRSAAMQEI 149
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 565 bits (1458), Expect = 0.0 Identities = 205/474 (43%), Positives = 297/474 (62%), Gaps = 12/474 (2%) Query: 5 VWILDDDSSIRWVLEKALQSAKFSCASFAAAESLWQALEMTQPQVIVSDIRMPGTDGLTL 64 + + DDD++IR VL +AL A + + A +LW+ + ++V+D+ MP + L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 65 LERLQNHYPHIPVIIMTAHSDLDSAVSAYQAGAFEYLPKPFDIDEAISLVDRALTHAKEQ 124 L R++ P +PV++M+A + +A+ A + GA++YLPKPFD+ E I ++ RAL K + Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRR 125 Query: 125 SSSITVEEPLVATPEIIGEAPAMQEVFRAIGRLSRSSISVLINGQSGTGKELVASALHKH 184 S +E+ ++G + AMQE++R + RL ++ ++++I G+SGTGKELVA ALH + Sbjct: 126 PS--KLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDY 183 Query: 185 SPRKGKPFIAINMAAIPKDLIESELFGHEKGAFTGAGSVRQGRFEQANGGTLFLDEIGDM 244 R+ PF+AINMAAIP+DLIESELFGHEKGAFTGA + GRFEQA GGTLFLDEIGDM Sbjct: 184 GKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDM 243 Query: 245 PLDVQTRLLRVLADGQFYRVGGHSPVQVDVRIIAATHQDLEQLVYQGGFREDLFHRLNVI 304 P+D QTRLLRVL G++ VGG +P++ DVRI+AAT++DL+Q + QG FREDL++RLNV+ Sbjct: 244 PMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVV 303 Query: 305 RVHLPPLSQRREDIPQLARHFLMIAAKEIAVEPKVLTKEAATKLSQLPWPGNVRQLENTC 364 + LPPL R EDIP L RHF+ A KE ++ K +EA + PWPGNVR+LEN Sbjct: 304 PLRLPPLRDRAEDIPDLVRHFVQQAEKE-GLDVKRFDQEALELMKAHPWPGNVRELENLV 362 Query: 365 RWLTVMASGQEILPLDLPPELLQEPKLNNAQTSDSDDWQGALKLFIDQRLSD-------- 416 R LT + I + EL E + + + + ++ +++ + Sbjct: 363 RRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDA 422 Query: 417 -GDSDLLTEVQPAFERILLQTALKHTNGHKQEAAKRLGWGRNTLTRKLKELEMD 469 S L V E L+ AL T G++ +AA LG RNTL +K++EL + Sbjct: 423 LPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>PF06580#Sensor histidine kinase Length = 349 Score = 41.4 bits (97), Expect = 3e-06 Identities = 40/257 (15%), Positives = 86/257 (33%), Gaps = 58/257 (22%) Query: 98 KYLALIELRQVDQQRRIHQQLTQDAQQQAAQYLVRNLAHEIKNPLGGLRGAAQLLSRELK 157 + + ++DQ + + Q+AQ A + + H + N L +R Sbjct: 139 HFFKNYKQAEIDQWKM--ASMAQEAQLMALKAQIN--PHFMFNALNNIRA---------- 184 Query: 158 EPELHEFTDLIIEQADRLRNLVDRL-------LGPQRPTQHSLYNIHEVIQKVVQLVNVT 210 LI+E + R ++ L L Q SL + V+ +QL ++ Sbjct: 185 ---------LILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQ 235 Query: 211 LPSNIELTQDYDPSIPDIEMDPDQLQQAILNIVQNAIQ-ALEPKGGNIRLKTRTQHQITI 269 ++ +P+I D+++ P +Q +V+N I+ + +I + Sbjct: 236 FEDRLQFENQINPAIMDVQVPPMLVQT----LVENGIKHGIAQL--------PQGGKILL 283 Query: 270 GTKRHKLVLMLSIIDDGPGIQPELMDTLFYPMVTGREQGSGLGLSIAHNFARLHGG---R 326 + + L + + G ++ +G GL ++ G + Sbjct: 284 KGTKDNGTVTLEVENTGSLALKN------------TKESTGTGLQNVRERLQMLYGTEAQ 331 Query: 327 IDCDSTVGHTEFTITLP 343 I G + +P Sbjct: 332 IKLSEKQGKVNAMVLIP 348
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 31.7 bits (72), Expect = 0.006 Identities = 29/136 (21%), Positives = 52/136 (38%), Gaps = 21/136 (15%) Query: 261 QALDFKQTGYSCEFTVKRAGLADLRLSVNLPGEHNVLN--------ALAAIAVATEDDIE 312 Q ++ K + +R G+ D L+ N GE + A+ + A + Sbjct: 16 QLIESKDGNVLAKGLAERIGINDSLLTHNANGEKIKIKKDMKDHKDAIKLVLDALVN--S 73 Query: 313 DAAIIKALAEFQGIGRRFQQIGEFATSK--------GEIKLVDDYG--HHPSEVAATIKA 362 D +IK ++E +G R GE+ TS I + H+P+ + IKA Sbjct: 74 DYGVIKDMSEIDAVGHRVVHGGEYFTSSVLITDDVLKAITDCIELAPLHNPANIEG-IKA 132 Query: 363 ARLGWPERRLVMIYQP 378 P+ +V ++ Sbjct: 133 CTQIMPDVPMVAVFDT 148
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 61.3 bits (149), Expect = 1e-12 Identities = 49/222 (22%), Positives = 90/222 (40%), Gaps = 20/222 (9%) Query: 150 SGMRMEAKVHIVTC----ANDMAKNITK-SVERCGLKVDDLVFSAIASADSVLTDDEKDL 204 S M ++ C A + + + S + G + L+ +A+A + Sbjct: 100 SNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEAT 159 Query: 205 GVCLVDIGGGTTDIAVYTNGALRHCAVVPVAGNQVTNDIAKIFR------TPLSHAEQIK 258 G +VDIGGGTT++AV + + + + V + G++ I R + AE+IK Sbjct: 160 GSMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIK 219 Query: 259 VQHASARSAMVSREDSIEVPS---VGGRPSR-SMSRHTLAEVVEPRYQELFELILKQLRD 314 + SA IEV G P +++ + + E ++ + ++ L Sbjct: 220 HEIGSAYPG--DEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQ 277 Query: 315 SGLE---DQVAAGIVITGGTASIEGAVDIAEATFGMPVRMAQ 353 E D G+V+TGG A + + G+PV +A+ Sbjct: 278 CPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAE 319
>PF06580#Sensor histidine kinase Length = 349 Score = 32.1 bits (73), Expect = 0.002 Identities = 15/65 (23%), Positives = 28/65 (43%) Query: 6 FIQGRNGATRWQPGKRWLLLPILLIAAGTGLYQHNAKQLTQQQATVDGERMAREEQKDEL 65 FI + A + +++ + LY +QA +D +MA Q+ +L Sbjct: 104 FINTKPVAFTLPLALSIIFNVVVVTFMWSLLYFGWHFFKNYKQAEIDQWKMASMAQEAQL 163 Query: 66 IALKS 70 +ALK+ Sbjct: 164 MALKA 168
>SECA#SecA protein signature. Length = 901 Score = 1313 bits (3400), Expect = 0.0 Identities = 646/906 (71%), Positives = 749/906 (82%), Gaps = 6/906 (0%) Query: 1 MFGKLLTKVFGSRNDRTLKAFGKVVTKINALEAEYEKLSDEELKAKTLHFRERLDGGETL 60 M KLLTKVFGSRNDRTL+ KVV INA+E E EKLSDEELK KT FR RL+ GE L Sbjct: 1 MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVL 60 Query: 61 EGVLPEAFATVREASKRVFEMRHFDVQLIGGMILDSNRIAEMRTGEGKTLTATLPAYLNG 120 E ++PEAFA VREASKRVF MRHFDVQL+GGM+L+ IAEMRTGEGKTLTATLPAYLN Sbjct: 61 ENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNA 120 Query: 121 LTGKGVHVITVNDYLAGRDAENNRPLFEFLGLTVGINVAGLGQVEKKAAYDADITYGTNN 180 LTGKGVHV+TVNDYLA RDAENNRPLFEFLGLTVGIN+ G+ K+ AY ADITYGTNN Sbjct: 121 LTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNN 180 Query: 181 EFGFDYLRDNMAFSPSERVQRPLHYALIDEVDSILIDEARTPLIISGAAEDSSELYIKIN 240 E+GFDYLRDNMAFSP ERVQR LHYAL+DEVDSILIDEARTPLIISG AEDSSE+Y ++N Sbjct: 181 EYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVN 240 Query: 241 TLIPNLIAQDKEDTEDEIGVGDYSVDEKSKQVHMTERGQEKVEVLLTERGMLAEGDSLYS 300 +IP+LI Q+KED+E G G +SVDEKS+QV++TERG +E LL + G++ EG+SLYS Sbjct: 241 KIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYS 300 Query: 301 AANISLLHHVNAALRAHTLFEKDVDYIVQDNEVVIVDEHTGRTMPGRRWSEGLHQAVEAK 360 ANI L+HHV AALRAH LF +DVDYIV+D EV+IVDEHTGRTM GRRWS+GLHQAVEAK Sbjct: 301 PANIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAK 360 Query: 361 EGVHIQNENQTLASITFQNFFRQYEKLAGMTGTADTEAFEFQHIYGLDTVVVPTNRPMVR 420 EGV IQNENQTLASITFQN+FR YEKLAGMTGTADTEAFEF IY LDTVVVPTNRPM+R Sbjct: 361 EGVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIR 420 Query: 421 KDHADLVYLTAEEKYAAIVKDIVGCRERGQPVLVGTVSIEQSELLHSLLKKEKIPHEILN 480 KD DLVY+T EK AI++DI +GQPVLVGT+SIE+SEL+ + L K I H +LN Sbjct: 421 KDLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLN 480 Query: 481 AKFHEREADIVAQAGRTGAVTVATNMAGRGTDIVLGGNWNMEIEVLANPTTEQKAKIKAD 540 AKFH EA IVAQAG AVT+ATNMAGRGTDIVLGG+W E+ L NPT EQ KIKAD Sbjct: 481 AKFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKAD 540 Query: 541 WQIRHDEVVGAGGLHILGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDSLMRIFAS 600 WQ+RHD V+ AGGLHI+GTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMED+LMRIFAS Sbjct: 541 WQVRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFAS 600 Query: 601 DRVSSMMKKLGMEEGEAIEHPWVSRAIENAQRKVEARNFDIRKQLLEFDDVANDQRQVVY 660 DRVS MM+KLGM+ GEAIEHPWV++AI NAQRKVE+RNFDIRKQLLE+DDVANDQR+ +Y Sbjct: 601 DRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIY 660 Query: 661 AQRNELMDADSIQDTITNIQEDVVNGLVDQYIPRQSVEELWDIEGLEQRLKQEYAMSLPI 720 +QRNEL+D + +TI +I+EDV +D YIP QS+EE+WDI GL++RLK ++ + LPI Sbjct: 661 SQRNELLDVSDVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPI 720 Query: 721 QEWLDKEDDLHEETLRERIVDTWVNAYKAKEEMVGEQVLRQFEKAVMLQTLDGLWKEHLS 780 EWLDKE +LHEETLRERI+ + Y+ KEE+VG +++R FEK VMLQTLD LWKEHL+ Sbjct: 721 AEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLA 780 Query: 781 AMDHLRQGIHLRGYAQKNPKQEYKRESFELFQQMLESLKHDVISILSKVQVQAQSDVEEM 840 AMD+LRQGIHLRGYAQK+PKQEYKRESF +F MLESLK++VIS LSKVQV+ +VEE+ Sbjct: 781 AMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEEL 840 Query: 841 EERRRQEDAKIRRDYQHAEAEALVGAEESAALAATQPTVRDGEKIGRNDPCPCGSGKKYK 900 E++RR E ++ A+ + L ++ +A AA K+GRNDPCPCGSGKKYK Sbjct: 841 EQQRRMEAERL------AQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYK 894 Query: 901 QCHGKL 906 QCHG+L Sbjct: 895 QCHGRL 900
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 332 bits (852), Expect = e-116 Identities = 161/303 (53%), Positives = 203/303 (66%), Gaps = 14/303 (4%) Query: 1 MTELISVFGQNPWLFIALSFVFAAVIGSFLNVVIHRMPVMMKRDWQQECNHYLSEYKKEV 60 M L+ + PWL+ +L F+F+ +IGSFLNVVIHR+P+M++R+WQ E Y + Sbjct: 1 MALLLELAHGLPWLYFSLVFLFSLMIGSFLNVVIHRLPIMLEREWQAEYRSYFNPD---- 56 Query: 61 FDSNKKQLEAPIDAFPEKYNLVVPGSACPKCKANIKAVHNLPILGWLMLKGKCATCSTKI 120 YNL+VP S CP C I A+ N+P+L WL L+G+C C I Sbjct: 57 ----------DEGVDEPPYNLMVPRSCCPHCNHPITALENIPLLSWLWLRGRCRGCQAPI 106 Query: 121 SPRYPIVELITGALVAFLAWHFGPTLEFALTSLLTFCLVALTGIDLDEMLLPDQITLPLL 180 S RYP+VEL+T L +A P LLT+ LVALT IDLD+MLLPDQ+TLPLL Sbjct: 107 SARYPLVELLTALLSVAVAMTLAPGWGTLAALLLTWVLVALTFIDLDKMLLPDQLTLPLL 166 Query: 181 WLGLIINLSGTFATTSDALIGAAAGYLSLWSVFWLFKLLTGKDGMGYGDFKLLAVFGAWF 240 W GL+ NL G F + DA+IGA AGYL LWS++W FKLLTGK+GMGYGDFKLLA GAW Sbjct: 167 WGGLLFNLLGGFVSLGDAVIGAMAGYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWL 226 Query: 241 GWQVLPLVILLSSLVGAVVGIALIVFKKLNHGNPIPFGPYIAAAGWIAMIWGESITNWYL 300 GWQ LP+V+LLSSLVGA +GI LI+ + + PIPFGPY+A AGWIA++WG+SIT WYL Sbjct: 227 GWQALPIVLLLSSLVGAFMGIGLILLRNHHQSKPIPFGPYLAIAGWIALLWGDSITRWYL 286 Query: 301 STL 303 + Sbjct: 287 TNF 289
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 399 bits (1028), Expect = e-140 Identities = 118/405 (29%), Positives = 214/405 (52%), Gaps = 10/405 (2%) Query: 24 TFQWKGTNRDGAKTSGELRGVSSAEIRAQLKAQGVVPKNVRKKSAP---------LFKSE 74 + ++ + G K G S+ + R L+ +G+VP +V + + + Sbjct: 3 QYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLRRK 62 Query: 75 KKIKPMDIAMMTRQIATMLAAGVPIVTTLELLGKGHEKAKMRELLATIVNDVQSGIPLSD 134 ++ D+A++TRQ+AT++AA +P+ L+ + K EK + +L+A + + V G L+D Sbjct: 63 IRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLAD 122 Query: 135 SLRPHRKYFDDLYVDLVAAGEHSGSLDAVFDRIATYREKSEALKSKIKKAMFYPAAVVIV 194 +++ F+ LY +VAAGE SG LDAV +R+A Y E+ + ++S+I++AM YP + +V Sbjct: 123 AMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLTVV 182 Query: 195 AIMVTALLLLFVVPQFEDIFNGFGAELPAFTQFIISISRWLQASWYIFVIAIIVGIWSFR 254 AI V ++LL VVP+ + F LP T+ ++ +S ++ ++A++ G +F Sbjct: 183 AIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMAF- 241 Query: 255 RAHLNSQKFRDRVDEFVLKIPAIGDILHKGAMARFARTLATTFAAGVPLIDGLESAAGAS 314 R L +K R +L +P IG I AR+ARTL+ A+ VPL+ + + Sbjct: 242 RVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDVM 301 Query: 315 GNAVYRKAILKIRTEVMSGMQMNVAMRTTGLFPDMLIQMVMIGEESGSLDNMLNKVANIY 374 N R + V G+ ++ A+ T LFP M+ M+ GE SG LD+ML + A+ Sbjct: 302 SNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADNQ 361 Query: 375 EMQVDDAVDGLSSLIEPVMMVVIGTVVGGLIVGMYLPIFEMGNVV 419 + + + L EP+++V + VV +++ + PI ++ ++ Sbjct: 362 DREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>PF01206#SirA family protein Length = 76 Score = 92.1 bits (229), Expect = 8e-29 Identities = 18/71 (25%), Positives = 37/71 (52%) Query: 8 DYNLEIYGEPCPYPAVATLEAMQSLKPGEVLEVITDCSQSINNIPNDAKNHGYEVLDISQ 67 D +L+ G CP P + + + ++ GEVL V+ S+ + + +K G+E+L+ + Sbjct: 5 DQSLDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKE 64 Query: 68 QGVMLRYLLKK 78 + + LK+ Sbjct: 65 EDGTYHFRLKR 75
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 102 bits (255), Expect = 4e-26 Identities = 53/411 (12%), Positives = 123/411 (29%), Gaps = 81/411 (19%) Query: 2 SKTKLFFGIPVLIIALLTGGYYWWTQVRNFESTDNAYVESDISH-ISVKVPGYVTATFVT 60 S+ ++ ++ QV + + S S I V V Sbjct: 54 SRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVK 113 Query: 61 DNQHVKKGQLLAQLEDNQFRAKVAQNQAVLASAKAKLQTLNAQIDLQQALITQAQASVVA 120 + + V+KG +L +L A + Q+ L A+ + + Sbjct: 114 EGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDE 173 Query: 121 AEAERVRSQQQLTRATKLKVKNYSSQDAVDEAQAAFESATAHVDEIHAV----------- 169 + V ++ L + +K + + Q+ + + + A + A Sbjct: 174 PYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233 Query: 170 --------------------LVAKQRELKVFNAQLVEADSSVEQAKAGLQLAQI------ 203 ++ ++ + +L S +EQ ++ + A+ Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVT 293 Query: 204 ---------QLADTQ---------------------ITAPFTGIIGKRGAQ-QGQYVQPG 232 +L T I AP + + + +G V Sbjct: 294 QLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTA 353 Query: 233 QAIYSLVPDEAV-WITANFKETQIAKMHAGQKVTIELDAFSGKEFSGVIDSLSPASGAKF 291 + + +VP++ +TA + I ++ GQ I+++AF + G + K Sbjct: 354 ETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRY-GYLV-------GKV 405 Query: 292 SLLPAENATGNFTKIVQRIPVRIRLDSNAA-EKLEQGRIVPGLSALVKVDT 341 + + +V V I ++ N + + G++ ++ T Sbjct: 406 KNINLDAIEDQRLGLVFN--VIISIEENCLSTGNKNIPLSSGMAVTAEIKT 454
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 83.7 bits (207), Expect = 1e-19 Identities = 76/370 (20%), Positives = 133/370 (35%), Gaps = 27/370 (7%) Query: 8 KTEKKVAFSLASVFGLRMMGLFMIMPV--FALYGQHLEGFSPLWVGIAIGAYGLTQAILQ 65 K + + L++V L +G+ +IMPV L GI + Y L Q Sbjct: 2 KPNRPLIVILSTVA-LDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACA 60 Query: 66 IPMGILSDKFGRKPIILTGLLIFALGSLVAANAETIYGVVAGRALQGM-GAIAAAVLALA 124 +G LSD+FGR+P++L L A+ + A A ++ + GR + G+ GA A A Sbjct: 61 PVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYI 120 Query: 125 ADLTRDEQRTKVMAIIGMCIGFSFALSLLVGPIVAQHLGLSGLFFMTAGLALLGMLIVQL 184 AD+T ++R + + C GF ++G ++ FF A L L L Sbjct: 121 ADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFAAAALNGLNFLTGCF 179 Query: 185 LVPTPVGQAPKGDTVAAPEKLKRMLLDPQLFRLDAGIFILHLVLTAVFVALPLDLVDAGL 244 L+P + A L FR G+ ++ ++ F+ + V A L Sbjct: 180 LLPESHKGERRPLRREALNPLAS-------FRWARGMTVVAALMAVFFIMQLVGQVPAAL 232 Query: 245 ------------PKEEHWMLYFPAFMGAFFLMVPLIIIGVKRNNTKGMFQVALIIMMVAL 292 L + + + + R + + +I Sbjct: 233 WVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPV-AARLGERRALMLGMIADGTGY 291 Query: 293 GSMAMFANNLVVLSIAVVLFFTGFNYLEASLPSLIAKFCPVGDKGSAMGVYSTSQFLGAF 352 +A + I V+L G +L +++++ +G G + L + Sbjct: 292 ILLAFATRGWMAFPIMVLLASGGIG--MPALQAMLSRQVDEERQGQLQGSLAALTSLTSI 349 Query: 353 CGGLLGGGAY 362 G LL Y Sbjct: 350 VGPLLFTAIY 359
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 35.5 bits (81), Expect = 1e-04 Identities = 19/62 (30%), Positives = 27/62 (43%), Gaps = 4/62 (6%) Query: 157 PKPQQAPAQQGGYQQQPQQQAPQQGGYAPKPQSAPAPQQAPQQRPAPQPQQNFTPDLDDG 216 P+P P G + P Q + A P + PAP + P RP P+P + PD + Sbjct: 311 PRPDLTP----GSAEAPNAQPLPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPD 366 Query: 217 WD 218 D Sbjct: 367 TD 368
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 381 bits (979), Expect = e-129 Identities = 126/349 (36%), Positives = 187/349 (53%), Gaps = 34/349 (9%) Query: 237 TPASPFSNIIGESNKMLQLKTLIARVAKSPSSILISGESGTGKEVFAQAIHKYSDRSEQN 296 + ++G S M ++ ++AR+ ++ +++I+GESGTGKE+ A+A+H Y R Sbjct: 131 DDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGP 190 Query: 297 FVAINCAAIPEQLLESELFGYVKGAFTGALTKGKVGLIQAANNGTLFLDEIGDMSMTLQS 356 FVAIN AAIP L+ESELFG+ KGAFTGA T+ G + A GTLFLDEIGDM M Q+ Sbjct: 191 FVAINMAAIPRDLIESELFGHEKGAFTGAQTRST-GRFEQAEGGTLFLDEIGDMPMDAQT 249 Query: 357 KLLRVLEEREVMPLGSNASTPVNIRIISATNRNFAEMIAANEFREDLYYRLNVIPLYLPA 416 +LLRVL++ E +G ++RI++ATN++ + I FREDLYYRLNV+PL LP Sbjct: 250 RLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPP 309 Query: 417 LREREGDIELLVYYFLDRHSQAIGTCYPGITEEVINSLNAYHWPGNIRELSNLVEYLVNI 476 LR+R DI LV +F+ + + G +E + + A+ WPGN+REL NLV L Sbjct: 310 LRDRAEDIPDLVRHFVQQAEK-EGLDVKRFDQEALELMKAHPWPGNVRELENLVRRLT-A 367 Query: 477 VPSGDQIDIDLLPPYF-DTPQESCTPMVSINDDNVS------------------------ 511 + D I +++ +S + ++S Sbjct: 368 LYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSG 427 Query: 512 -----LEEMERIKIEDSINR-LGNRKLVAKELGIGVATLYRKLKKYRLS 554 L EME I ++ GN+ A LG+ TL +K+++ +S Sbjct: 428 LYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 41.6 bits (98), Expect = 5e-06 Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 9/70 (12%) Query: 6 TLIINGTLVDAQKQSQQQLLIIDGKIAAV---------DKVITDYPVDTEVIDASGLYVM 56 T+I N ++D + + + DG+IAA+ V TEVI G V Sbjct: 70 TVITNALILDHWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIVT 129 Query: 57 PGGIDVHTHF 66 GG+D H HF Sbjct: 130 AGGMDSHIHF 139
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 362 bits (931), Expect = e-128 Identities = 137/312 (43%), Positives = 181/312 (58%), Gaps = 14/312 (4%) Query: 1 MKPIAVVALGGNALLRRGDAPSFQNQLANIKIAAVAIAE-IAKEYRVAIVHGNGPQVGLI 59 M V+ALGGNAL +RG S++ + N++ A IAE IA+ Y V I HGNGPQVG + Sbjct: 1 MGKRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSL 60 Query: 60 SLQNL---SYKDVAPYPLDVLGAESEGMIGYMLAQELQNVMPHS----EVSTILTRIEVD 112 L + + P+DV GA S+G IGYM+ Q L+N + +V TI+T+ VD Sbjct: 61 LLHMDAGQATYGIPAQPMDVAGAMSQGWIGYMIQQALKNELRKRGMEKKVVTIITQTIVD 120 Query: 113 SQDPSMLDPTKFVGPVYNEDEAGLLAEANNWIMKRD-GDYVRRVVPSPKPMSILDRSSIN 171 DP+ +PTK VGP Y+E+ A LA WI+K D G RRVVPSP P ++ +I Sbjct: 121 KNDPAFQNPTKPVGPFYDEETAKRLAREKGWIVKEDSGRGWRRVVPSPDPKGHVEAETIK 180 Query: 172 TLLGSGHIVICCGGGGIPVCKSDHGYIGVEGVIDKDLSATLLAKQLKADKLLILTDADAV 231 L+ G IVI GGGG+PV D GVE VIDKDL+ LA+++ AD +ILTD + Sbjct: 181 KLVERGVIVIASGGGGVPVILEDGEIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVNGA 240 Query: 232 YLDWGTENQRALHRTTPEELSQY----SFAAGSMGPKVEAVTDFALSGGK-AYIGALEHG 286 L +GTE ++ L EEL +Y F AGSMGPKV A F GG+ A I LE Sbjct: 241 ALYYGTEKEQWLREVKVEELRKYYEEGHFKAGSMGPKVLAAIRFIEWGGERAIIAHLEKA 300 Query: 287 LDVLAERSGTCV 298 ++ L ++GT V Sbjct: 301 VEALEGKTGTQV 312
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 27.8 bits (61), Expect = 0.030 Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 14/100 (14%) Query: 66 NKQASLKAQNCSCCNKSFTTRMKIAELAGEFQSYFLCVKCEKQISKRAESTFLLNQLLSP 125 K LKA S + T +K A +++S + T LL +L++ Sbjct: 47 TKAGDLKAGTKSGESAINTVGLKPPTDAAR-----------EKLSSEGQLTLLLGKLMT- 94 Query: 126 DFIQKNSSFSDLESMVESSGIQLKTQDDLKLEVWDEFITA 165 + + S S LES + +++Q ++ ++V EF TA Sbjct: 95 --LLGDVSLSQLESRLAVWQAMIESQKEMGIQVSKEFQTA 132
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 83.3 bits (206), Expect = 1e-20 Identities = 30/124 (24%), Positives = 56/124 (45%), Gaps = 1/124 (0%) Query: 1 MQNPHILIVEDEAVTRNTLRSIFEAEGYVVTEANDGAEMHKAMQDNKVNLVVMDINLPGK 60 M IL+ +D+A R L GY V ++ A + + + +LVV D+ +P + Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 NGLLLARELREIN-NIGLIFLTGRDNEVDKILGLEIGADDYITKPFNPRELTIRARNLLT 119 N L +++ ++ ++ ++ ++ + I E GA DY+ KPF+ EL L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 120 RVNS 123 Sbjct: 121 EPKR 124
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 30.2 bits (68), Expect = 0.019 Identities = 20/87 (22%), Positives = 29/87 (33%), Gaps = 11/87 (12%) Query: 213 DYSAALLAEALQAYAVEIWTDVAGIYTTDPRLAPNASPIAEISFNEAAEMATFGAKVLHP 272 D + LAE + A I TDV G + E+ E + G Sbjct: 216 DLAGEKLAEEVNADIFMILTDVNGAALY--YGTEKEQWLREVKVEELRKYYEEGH--FKA 271 Query: 273 ATILPAVRQKIQVFVGSSWAPEQGGTW 299 ++ P V I+ F+ E GG Sbjct: 272 GSMGPKVLAAIR-FI------EWGGER 291
>PF01540#Adhesin lipoprotein Length = 475 Score = 27.0 bits (59), Expect = 0.034 Identities = 12/17 (70%), Positives = 13/17 (76%) Query: 79 SAGDYPAAISKLNALEE 95 S GDYPA ISKL+A E Sbjct: 84 SYGDYPAIISKLSAAVE 100
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 186 bits (473), Expect = 6e-61 Identities = 102/242 (42%), Positives = 149/242 (61%), Gaps = 12/242 (4%) Query: 6 KYSLVALAVVGLTACNQEQAVAVDAPVELKTEAQKEAYSVGASIGTYMAGHIKEQEELGL 65 K LV A++GL A+A L T+ K +YS+GA +G K + G+ Sbjct: 2 KMKLVTAAIMGLA---MSTAMAATDATSLTTDKDKLSYSIGADLG-------KNFKNQGI 51 Query: 66 NVDRSLIVTGFSEGLN-SELKLTQEEMQTILQSLDEKLNEKRQAQAAMLAEKSLAESQAF 124 +++ ++ G +G++ ++L LT+E+M+ +L + L KR A+ AE++ A+ AF Sbjct: 52 DINPDVLAKGMQDGMSGAQLILTEEQMKDVLSKFQKDLMAKRSAEFNKKAEENKAKGDAF 111 Query: 125 LDANKAKEGVVTTDSGLQYEVITEGTGDKPVAEDTVKVHYVGTLTDGTEFDSSVARGEPA 184 L ANK+K G+V SGLQY++I GTG KP DTV V Y GTL DGT FDS+ G+PA Sbjct: 112 LSANKSKPGIVVLPSGLQYKIIDAGTGAKPGKSDTVTVEYTGTLIDGTVFDSTEKAGKPA 171 Query: 185 TFPLNRVIPGWTEGVQLMSVGSKYKFVIPADLAYGDRDT-GTIPANSTLVFEVELLDIEK 243 TF +++VIPGWTE +QLM GS ++ +PADLAYG R G I N TL+F++ L+ ++K Sbjct: 172 TFQVSQVIPGWTEALQLMPAGSTWEVFVPADLAYGPRSVGGPIGPNETLIFKIHLISVKK 231 Query: 244 AA 245 AA Sbjct: 232 AA 233
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 62.5 bits (152), Expect = 9e-14 Identities = 25/159 (15%), Positives = 63/159 (39%), Gaps = 9/159 (5%) Query: 6 SVLVIDDHPLLRRGICQLVTSDSDFTLFGEAGSGLDALSAVSDNEPDIILLDLNMKGMTG 65 ++LV DD +R + Q ++ + + + + ++ + D+++ D+ M Sbjct: 5 TILVADDDAAIRTVLNQALS-RAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 66 LDTLNALRQEGVTSRIVILTVSDAKQDVIRLVRAGADGYLLKDTEPDLLLDMLKNAMLGH 125 D L +++ +++++ + I+ GA YL K + L+ ++ A+ Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL--- 119 Query: 126 RVISNTVQEYLSELNSSVNEQEWIENLTPRELEILQHLA 164 + S+L + + + EI + LA Sbjct: 120 ----AEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLA 154
>PF06580#Sensor histidine kinase Length = 349 Score = 38.3 bits (89), Expect = 6e-05 Identities = 20/113 (17%), Positives = 40/113 (35%), Gaps = 11/113 (9%) Query: 458 ITLDYKLPLQLLGAHQHIHILQLTREATLNAIKHASAKHIHISCQKVSSEK----VVISI 513 + + ++ ++ ++Q E N IKH A+ + K V + + Sbjct: 240 LQFENQINPAIMDVQVPPMLVQTLVE---NGIKHGIAQLPQGGKILLKGTKDNGTVTLEV 296 Query: 514 SDDGVGIEELKERDQHFGLGIMHERASRLSGV---VEFSQNKKGGATVTLTFP 563 + G + + GL + ER L G ++ S K+G + P Sbjct: 297 ENTGSLALKNTKESTGTGLQNVRERLQMLYGTEAQIKLS-EKQGKVNAMVLIP 348
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 41.2 bits (96), Expect = 7e-07 Identities = 21/91 (23%), Positives = 36/91 (39%) Query: 74 ITKHHFSGWQADAFRERLSAMQQKQIILAGIETHVCVYQTCRDLLANGYQTHLVADAMSS 133 +TK +S ++ E + + Q+I+ GI H+ T + + V DA++ Sbjct: 121 LTKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVAD 180 Query: 134 REQSNKVSGLEMMLSHGAMQTNVESLLFELQ 164 LE A +SLL +LQ Sbjct: 181 FSLEKHQMALEYAAGRCAFTVMTDSLLDQLQ 211
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 29.1 bits (65), Expect = 0.019 Identities = 17/124 (13%), Positives = 41/124 (33%), Gaps = 4/124 (3%) Query: 276 LRVNPEDMNALNNYAIMLSAQDRLDEWADVHKVLELARIRNPYYYYGMAQQAYFDKDYQD 335 ++ + + L + A + ++ V + L + + ++ G+ Y Sbjct: 29 NEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDL 88 Query: 336 ALLWYKRAIA--KADYRHEFYFGLSRTYWVTGDEMRAQQSLKKALSLTTDGQHKRRYQSK 393 A+ Y + R F+ G+ A+ L A L D + ++ Sbjct: 89 AIHSYSYGAIMDIKEPRFPFHAAEC--LLQKGELAEAESGLFLAQELIADKTEFKELSTR 146 Query: 394 LHAM 397 + +M Sbjct: 147 VSSM 150
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 31.0 bits (70), Expect = 0.006 Identities = 10/28 (35%), Positives = 13/28 (46%), Gaps = 2/28 (7%) Query: 17 GCGELGKEVAIELQRYGIEVIGVD--RY 42 G L K V LQ+ G V+G +Y Sbjct: 62 GWATLDKAVGGILQQQGWPVVGWSSLKY 89
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 53.3 bits (128), Expect = 7e-10 Identities = 48/321 (14%), Positives = 102/321 (31%), Gaps = 82/321 (25%) Query: 66 INPAVRGVVVSVEVEPNTPIKKGDVLFRIDPTPFQAIVKQKRAALVAAELEVPQLEA--- 122 I P +V + V+ ++KGDVL ++ +A + +++L+ A LE + + Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSR 158 Query: 123 AWETTKAAVTRATADRDRTKSAFERYEKGRKRGGVNSPFTEL--ELDNKRQFYFASEAQL 180 + E K + + + E E R + F+ + K A+ Sbjct: 159 SIELNKLPELKLPDEPYFQNVSEE--EVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAER 216 Query: 181 TAANA-------------EEL-------------RMRL---------------AYESNVD 199 A L + + Y+S ++ Sbjct: 217 LTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLE 276 Query: 200 GVNTKVAGIQ---------------GELEKAQFDLDQ--------------TVVKAPADG 230 + +++ + +L + ++ +V++AP Sbjct: 277 QIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSV 336 Query: 231 MVTQMALRPGIVAVPMPLRPLLSFIPDEERMFVGAFWQNSLL-RLKEGDEAEIILDAAPG 289 V Q+ + V L+ +P+++ + V A QN + + G A I ++A P Sbjct: 337 KVQQLKVH-TEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPY 395 Query: 290 Q---VFKGKVAKVLPAMAEGE 307 GKV + E + Sbjct: 396 TRYGYLVGKVKNINLDAIEDQ 416
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 28.8 bits (64), Expect = 0.048 Identities = 18/79 (22%), Positives = 33/79 (41%), Gaps = 9/79 (11%) Query: 390 DLPDT------EIRQAIFLIH-LQRRQLDPMQFDLAQLAKVSQGFSG--AEIEQAVISAI 440 D+P + +A+ LIH +Q +D + + ++S + Q I + Sbjct: 16 DMPQNKVSWVPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCVQLGIPVV 75 Query: 441 YTAKASEREVDQSALLEEL 459 YTA+ + D ALL + Sbjct: 76 YTAQPGSQNPDDRALLTDF 94
>PF06580#Sensor histidine kinase Length = 349 Score = 42.5 bits (100), Expect = 2e-06 Identities = 22/127 (17%), Positives = 43/127 (33%), Gaps = 30/127 (23%) Query: 301 LDVPEETIYLIAEPSLVERALQNLVTNA------QRFSTDDIIVKISQDSDGVRLSVTDD 354 + I + P ++ +Q LV N Q I++K ++D+ V L V + Sbjct: 244 NQINPA-IMDVQVPPML---VQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENT 299 Query: 355 GEGILEEDQSKIFEPFYRSASSKNGNKGHGLGLAIIKRIMDRHHGE---VSLQSRPGFTQ 411 G L+ + + G GL ++ + +G + L + G Sbjct: 300 GSLALKNTK-----------------ESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVN 342 Query: 412 FTLYWPA 418 + P Sbjct: 343 AMVLIPG 349
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 74.5 bits (183), Expect = 2e-17 Identities = 32/135 (23%), Positives = 61/135 (45%), Gaps = 2/135 (1%) Query: 9 RVLLVEDDIRLANLIVDFLKSHGMHVEVERRGDTVLTRLINYKPDIILLDIMLPGMDGLT 68 +L+ +DD + ++ L G V + T+ + D+++ D+++P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 69 LCEKLPDYFAG-PILLMSALGSNEDQIKGLELGADDYVVKPVDPSLLVARINNLL-RRQA 126 L ++ P+L+MSA + IK E GA DY+ KP D + L+ I L + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 127 KPAQVESHCLSFGKL 141 +P+++E L Sbjct: 125 RPSKLEDDSQDGMPL 139
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 40.7 bits (95), Expect = 7e-07 Identities = 22/86 (25%), Positives = 37/86 (43%), Gaps = 4/86 (4%) Query: 70 IAVRDGDIVGQIGMEVFNNPRRKHVANIGMAVDEAYRGIGIASAMLEAMISLAQNWLAVR 129 + + + +G+I + N + +I AV + YR G+ +A+L I A+ Sbjct: 69 LYYLENNCIGRIKIRSNWN-GYALIEDI--AVAKDYRKKGVGTALLHKAIEWAKE-NHFC 124 Query: 130 RIELEVYTDNHLAISLYKKHGFVIEG 155 + LE N A Y KH F+I Sbjct: 125 GLMLETQDINISACHFYAKHHFIIGA 150
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 34.9 bits (80), Expect = 5e-05 Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 5/67 (7%) Query: 83 LYLHDIALSSKAQGKGAGRAALAILIEFARCHHYPNISLVAVQG----AHHYWAKQGFKA 138 + DIA++ + KG G A L IE+A+ +H+ + L Q A H++AK F Sbjct: 90 ALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLML-ETQDINISACHFYAKHHFII 148 Query: 139 KSINKDL 145 +++ L Sbjct: 149 GAVDTML 155
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 136 bits (343), Expect = 1e-37 Identities = 71/210 (33%), Positives = 96/210 (45%), Gaps = 24/210 (11%) Query: 124 AGMKVCIIDSGLDRSNGDFVWNNISG----DNDGGTGNWDENGGPHGTHVAGTIGAADNN 179 G+KV ++D+G D + D I G D+D G ++ HGTHVAGTI A +N Sbjct: 41 RGVKVAVLDTGCDADHPDLKARIIGGRNFTDDDEGDPEIFKDYNGHGTHVAGTIAATENE 100 Query: 180 IGVVGMAPGVDMHIIKVFNADGWGYSSDLAHAANLCSDAGANIISMSLGGGGSNSTESNA 239 GVVG+AP D+ IIKV N G G + + +IISMSLGG A Sbjct: 101 NGVVGVAPEADLLIIKVLNKQGSGQYDWIIQGIYYAIEQKVDIISMSLGGPEDVPELHEA 160 Query: 240 FQSFSDAGGLVVAAAGNDGNSVRS-----YPAGYPSVMMVGANDATDTIADFSQYPGCTT 294 + + LV+ AAGN+G+ YP Y V+ VGA + ++FS Sbjct: 161 VKKAVASQILVMCAAGNEGDGDDRTDELGYPGCYNEVISVGAINFDRHASEFSNSNN--- 217 Query: 295 GRGKKQRTDTSICVEIAAGGVDTLSTYPAG 324 V++ A G D LST P G Sbjct: 218 ------------EVDLVAPGEDILSTVPGG 235 Score = 46.4 bits (110), Expect = 2e-07 Identities = 25/106 (23%), Positives = 35/106 (33%), Gaps = 6/106 (5%) Query: 408 TLGDTNATTIPAAGATFEDRTAIIAASSANLSIG-TSDYGFMSGTSMATPAVSGIAARVW 466 ++G N + + + ++A LS Y SGTSMATP V+G A + Sbjct: 199 SVGAINFDRHASEFSNSNNEVDLVAPGEDILSTVPGGKYATFSGTSMATPHVAGALALIK 258 Query: 467 SN-----HNQCTGEEIRAALNASARDSGASGHDVYFGHGIADAAAA 507 T E+ A L G S G A Sbjct: 259 QLANASFERDLTEPELYAQLIKRTIPLGNSPKMEGNGLLYLTAVEE 304
>SECA#SecA protein signature. Length = 901 Score = 30.6 bits (69), Expect = 0.012 Identities = 53/267 (19%), Positives = 103/267 (38%), Gaps = 35/267 (13%) Query: 10 PEILRAISECGYE--KMTPIQQQAIPAVRRGQDVLASAQTGTGKTAAFALPILQKMLDNP 67 PE + E M Q + + + +A +TG GKT LP L Sbjct: 65 PEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNAL--- 121 Query: 68 STTGRSNARALILTPTRELAAQIADNINDYAKYLDMKVVTVLGGVKMDSQATKLKRGADI 127 TG+ ++T LA + A+N ++L + V L G M + A + ADI Sbjct: 122 --TGKG---VHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPG--MPAPAKREAYAADI 174 Query: 128 IIATPGRLLEHIVACNLSLS-------NVDFLVLDEADRMLDMGFSADIQKILQAVNKKR 180 T + N++ S + + ++DE D +L +++ R Sbjct: 175 TYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSIL--------------IDEAR 220 Query: 181 QNLLFSATFSTAVKQLANVMMVKPNIIAADKQNTTAVTVSQVVYPVEQRRKRELLSELIG 240 L+ S + + V + P++I +K+++ + + V+++ ++ L+E G Sbjct: 221 TPLIISGPAEDSSEMYKRVNKIIPHLIRQEKEDSETFQG-EGHFSVDEKSRQVNLTER-G 278 Query: 241 KKNWKQVLVFTATRDAADKLEKELNLD 267 +++LV D + L N+ Sbjct: 279 LVLIEELLVKEGIMDEGESLYSPANIM 305 Score = 29.1 bits (65), Expect = 0.048 Identities = 35/173 (20%), Positives = 64/173 (36%), Gaps = 42/173 (24%) Query: 220 SQVVYPVEQRRKRELLSELIGKKNWKQ-VLVFTATRDAADKLEKELNLDGIPTAVVHGEK 278 +VY E + + ++ ++ + Q VLV T + + ++ + EL GI V++ Sbjct: 424 PDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLN--- 480 Query: 279 AQGSRRRALREFKEGKM-RVLVATEVAARGLDIQ---------------GLEYVVNYDLP 322 A+ A + G V +AT +A RG DI E + Sbjct: 481 AKFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKAD 540 Query: 323 FLAED---------YV--------HRI-----GRTGRAGKSGVAISFVSREEE 353 + ++ RI GR+GR G +G + ++S E+ Sbjct: 541 WQVRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDA 593
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 138 bits (349), Expect = 7e-44 Identities = 69/132 (52%), Positives = 89/132 (67%), Gaps = 2/132 (1%) Query: 25 KAAKENIAIGSAYLADNKLKDGVTTTASGLQYQVLEPGTGTVHPKASDTVTVHYHGTLID 84 K A+EN A G A+L+ NK K G+ SGLQY++++ GTG P SDTVTV Y GTLID Sbjct: 99 KKAEENKAKGDAFLSANKSKPGIVVLPSGLQYKIIDAGTGA-KPGKSDTVTVEYTGTLID 157 Query: 85 GTVFDSSVERGEPIAFPLNRVIKGWTEGVQLMVVGEKARFFIPSELAYGNRS-AGKISGG 143 GTVFDS+ + G+P F +++VI GWTE +QLM G F+P++LAYG RS G I Sbjct: 158 GTVFDSTEKAGKPATFQVSQVIPGWTEALQLMPAGSTWEVFVPADLAYGPRSVGGPIGPN 217 Query: 144 STLIFDVELISI 155 TLIF + LIS+ Sbjct: 218 ETLIFKIHLISV 229
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 200 bits (511), Expect = 6e-64 Identities = 104/342 (30%), Positives = 157/342 (45%), Gaps = 30/342 (8%) Query: 24 AVYAAETDNSEAANEFDPYFYLGAKAGQMHYQNAC-ESWSISCDGNDVGFGGFVGYQAWQ 82 AV A A D +Y GAK G Y + + + N +G G F GYQ Sbjct: 9 AVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFINNNGPTHENQLGAGAFGGYQVNP 68 Query: 83 YLGFETAYLDLGEAVAHYSESGVNNTYTGSMKGWEISAVTRFSLSESFELFAKAGSVYWD 142 Y+GFE Y LG Y S N Y +G +++A + +++ +++ + G + W Sbjct: 69 YVGFEMGYDWLGRMP--YKGSVENGAYKA--QGVQLTAKLGYPITDDLDIYTRLGGMVWR 124 Query: 143 GDNRGPQS-RNSDSDWAPMLGAGVEYQLSPSWVARLEYQYIDSLGS--DLIGGSNGHLTT 199 D + +N D+ +P+ GVEY ++P RLEYQ+ +++G + + + + Sbjct: 125 ADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDAHTIGTRPDNGMLS 184 Query: 200 LGISYRFGQSATKAQPPVKETPVTLPEKIIPVTPKQIVLPALTVISLFDFDSSELTHSGS 259 LG+SYRFGQ A P V P PE V K L + LF+F+ + L G Sbjct: 185 LGVSYRFGQGE--AAPVVAPAPAPAPE----VQTKHFTLKSDV---LFNFNKATLKPEGQ 235 Query: 260 --LAPVIERLKQ--SPEAIANIKGYTDSKGNATYNQALSERRAQAVADYLIAAGIKPEQI 315 L + +L + + GYTD G+ YNQ LSERRAQ+V DYLI+ GI ++I Sbjct: 236 AALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPADKI 295 Query: 316 EVHGYGEQFPLMKNDT---------PEHRHENRRVLIHIQST 348 G GE P+ N + +RRV I ++ Sbjct: 296 SARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKGI 337
>INTIMIN#Intimin signature. Length = 939 Score = 35.8 bits (82), Expect = 0.002 Identities = 54/268 (20%), Positives = 93/268 (34%), Gaps = 28/268 (10%) Query: 72 SDGATKDVSQEVSWSSSEPTLATISTN--GVAMGAL-AGEVQITASLPPVQEGGMVLTDS 128 A VS + ++ + + +TN G A L + + E L + Sbjct: 589 VAQANVPVSFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNAN 648 Query: 129 AALKVTDAALMALNIEPGQAQILVGMSQSYRALALFADGHQ----QDVTNDASWTSLDTA 184 A + V I+ + + + G + Q+VT + L + Sbjct: 649 AVIFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKGDKPVSNQEVTFTTTLGKLSNS 708 Query: 185 TATIESAGESIGLATGVTVGVTQVKANFS--AQEALATLVVLATKPS------QLLINPV 236 T ++ G + T T G + V A S A + A V T + +++ V Sbjct: 709 TEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGTGV 768 Query: 237 DEVLPNGTSLQYQAHLILEDGLSIDVTTQSAWHSSSVDIASID-NQGFLVAKTLGQTRVT 295 LP Q +L G + W S++ IAS+D + G + K G T ++ Sbjct: 769 KGKLPTVWLQYGQVNLKASGG-----NGKYTWRSANPAIASVDASSGQVTLKEKGTTTIS 823 Query: 296 ATLSFAGISLLDTTSATVVDAKVSNLIV 323 S D +AT A ++LIV Sbjct: 824 VISS-------DNQTATYTIATPNSLIV 844
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 59.5 bits (144), Expect = 2e-14 Identities = 25/74 (33%), Positives = 44/74 (59%), Gaps = 2/74 (2%) Query: 1 MHKTRGFTLIELMIVVAIVGILASIAYPSYIDYVTKSARSEGVAAVLRVANLQEQYYLDN 60 K RGFTL+E+M+V+ I+G+LAS+ P+ + K+ + + V+ ++ + N + Y LDN Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDN 63 Query: 61 RAFATDLKKLGLSA 74 + T GL + Sbjct: 64 HHYPT--TNQGLES 75
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 47.2 bits (112), Expect = 2e-09 Identities = 18/45 (40%), Positives = 30/45 (66%) Query: 3 NKKQGFTLVELMITIVVAGILLSIAVPSLVSMYEQTRVNSNVEKI 47 +K++GFTL+E+M+ IV+ G+L S+ VP+L+ E+ V I Sbjct: 5 DKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDI 49
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 40.6 bits (95), Expect = 5e-07 Identities = 17/51 (33%), Positives = 30/51 (58%), Gaps = 3/51 (5%) Query: 4 RTAGFTLIELMVTLVVATILIVIAVPSL---SQFYEAQRAKSAIRVIQQTL 51 + GFTL+E+MV +V+ +L + VP+L + + Q+A S I ++ L Sbjct: 6 KQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENAL 56
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 34.0 bits (78), Expect = 0.003 Identities = 27/146 (18%), Positives = 56/146 (38%), Gaps = 29/146 (19%) Query: 67 SVVDAITAEDIGKFPDGDVGESLARIPGVTVNRQFGQGQQVSIRGASSQLTRTLLNGHAV 126 S T +DI + +V ++L+R+ GV + FG + I Sbjct: 144 SDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQYAMRI----------------- 186 Query: 127 ASTGWFDQQAIDRSFNYSLLPPEMVSGIEVYKSSQADLPEGGIGGT-VIVKTRKPLDLDA 185 W D + Y L P ++++ + K + G +GGT + + + A Sbjct: 187 ----WLDADLL---NKYKLTPVDVINQL---KVQNDQIAAGQLGGTPALPGQQLNASIIA 236 Query: 186 NTVFVSAKGDYGTISESTDPELSGLY 211 T F + + ++G ++ + + S + Sbjct: 237 QTRFKNPE-EFGKVTLRVNSDGSVVR 261
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 34.4 bits (79), Expect = 7e-04 Identities = 20/120 (16%), Positives = 44/120 (36%), Gaps = 9/120 (7%) Query: 101 AELAQQNAVLKQAVASRDVAVMNWERGRRLLPDGMISAQDMDELTSRKLTTA-AGVVQAE 159 E + V K + + +++ + +L+ Q KL + Sbjct: 262 VEAVNELRVYKSQLEQIESEILSAKEEYQLV------TQLFKNEILDKLRQTTDNIGLLT 315 Query: 160 AAVQAAELQLSYTKVYAPISGRISHSKVST-GDIITPQSEMASLV-QLQPMWVSFQVAEK 217 + E + + + AP+S ++ KV T G ++T + +V + + V+ V K Sbjct: 316 LELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNK 375 Score = 31.0 bits (70), Expect = 0.009 Identities = 22/162 (13%), Positives = 50/162 (30%), Gaps = 21/162 (12%) Query: 72 GQLLKRTFV-EGDDITAGDLLFEIDPSTYKAELAQQNAVLKQAVASR---DVAVMNWERG 127 ++K V EG+ + GD+L ++ +A+ + + L QA + + + E Sbjct: 104 NSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELN 163 Query: 128 RRLL-----PDGMISAQDMDELTSRKLTTAAGVVQAEAAVQAAELQLSYTKVYAPISGRI 182 + + + + L L + Q + +L+ K A + Sbjct: 164 KLPELKLPDEPYFQNVSEEEVLRLTSLIKEQ---FSTWQNQKYQKELNLDKKRAERLTVL 220 Query: 183 SHSKVSTGDIITPQSEMASLVQLQPMWVSFQVAEKKLISAQQ 224 + +S + L K+ I+ Sbjct: 221 ARINRYENLSRVEKSRLDDFSSL---------LHKQAIAKHA 253
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 998 bits (2582), Expect = 0.0 Identities = 441/1034 (42%), Positives = 647/1034 (62%), Gaps = 12/1034 (1%) Query: 2 ISDFFINRPKFAFVISTVLTLVGLIAIPVLSVSEFPEIAPPQVSVSTSYSGASADIVKDT 61 +++FFI RP FA+V++ +L + G +AI L V+++P IAPP VSVS +Y GA A V+DT Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 62 IAQPLEAEVNGVEGMLYMESKSANDGSYSLNVTFEVGTDADMAQVKVQNRVQQAMPRLPE 121 + Q +E +NG++ ++YM S S + GS ++ +TF+ GTD D+AQV+VQN++Q A P LP+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 122 EVKRQGVKVEKQSPNMLMVVNLVSPNETFDSLFITNYAGLNVKDALARQYGVSKVQVIGA 181 EV++QG+ VEK S + LMV VS N I++Y NVKD L+R GV VQ+ GA Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 182 LDYAMRIWLDPDKMASLGVTATDVIAALQEQNIQVAAGRIGAAPVDPEQQFQYTLQTKGR 241 YAMRIWLD D + +T DVI L+ QN Q+AAG++G P P QQ ++ + R Sbjct: 181 -QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 242 LKDPKEFYDVMIRANNDGSKVVVGDVARVELGSQTYDAQGKLNNKPSAIIAIYQSPDANA 301 K+P+EF V +R N+DGS V + DVARVELG + Y+ ++N KP+A + I + ANA Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 302 LEVGKAIKAEMENLSERFPNDLEYEVLYDTTEFVETSIKEVVQTLFISISLVVLVVFIFL 361 L+ KAIKA++ L FP ++ YDTT FV+ SI EVV+TLF +I LV LV+++FL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 362 QDVRSTLVPAIAIPVSLIGTFAFLLAFDMSINTVSLFALILAIGIVVDDAIVVVENVTRL 421 Q++R+TL+P IA+PV L+GTFA L AF SINT+++F ++LAIG++VDDAIVVVENV R+ Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 422 MQDEGLSPKEATSKAMKEVTGPIIATTLVLLAVFAPTAVMPGITGQMYAQFSVTICISVL 481 M ++ L PKEAT K+M ++ G ++ +VL AVF P A G TG +Y QFS+TI ++ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 482 ISSINALTLSPALCASLLRP----PKTHTKGFHAVFNKYFERFTGKYMKLVSLLTRKLAI 537 +S + AL L+PALCA+LL+P + GF FN F+ Y V + Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 538 VGVVYICLIVVTGGVAKILPSGFVPMEDKKAFMVDIQLPDGASLNRTEDVMRELVELTLA 597 ++Y ++ + LPS F+P ED+ F+ IQLP GA+ RT+ V+ ++ + L Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 598 --EPGVENVIHASGFSILTGSVSSNGGLMIVTLSTWSERESPDMVESAIVAKLQAKYAAN 655 + VE+V +GFS + N G+ V+L W ER + A++ + + + Sbjct: 600 NEKANVESVFTVNGFS--FSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKI 657 Query: 656 PAVKAMAFSLPPIPGVGSVGGFEFVLQDTQGRTPQELASVMRALIMKANEQP-EIAMAFS 714 + F++P I +G+ GF+F L D G L L+ A + P + Sbjct: 658 RDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRP 717 Query: 715 NFRADVPQMFVDVDRDKAKALGISLNEIFSTMQTMLGSMYVNDFNRFGKVFRVILQAESE 774 N D Q ++VD++KA+ALG+SL++I T+ T LG YVNDF G+V ++ +QA+++ Sbjct: 718 NGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAK 777 Query: 775 YRNSDRDISRFYVRSNTGEMVPLSTLVTVTPILGPDVMNNYNMFSSTTINGFPAPGFSSG 834 +R D+ + YVRS GEMVP S T + G + YN S I G APG SSG Sbjct: 778 FRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSG 837 Query: 835 DAITAMERAANESLPAGYTFEWTGQTYQEIKAGNLAPLIFSLALVFTYLFLVAQYESWTI 894 DA+ ME A++ LPAG ++WTG +YQE +GN AP + +++ V +L L A YESW+I Sbjct: 838 DAMALMENLASK-LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSI 896 Query: 895 PFAVILAVPIAVLGAFLNILLVGSDLNLYAQIGLVLLIGLACKNAILIVEFAKQLHE-EG 953 P +V+L VP+ ++G L L ++Y +GL+ IGL+ KNAILIVEFAK L E EG Sbjct: 897 PVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEG 956 Query: 954 KSILDAAQTAARLRFRAVLMTAFSFLLGVLPLVIATGAGAGSRRALGYSVFGGMLAATIV 1013 K +++A A R+R R +LMT+ +F+LGVLPL I+ GAG+G++ A+G V GGM++AT++ Sbjct: 957 KGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLL 1016 Query: 1014 GTLLVPVFYVIMQK 1027 VPVF+V++++ Sbjct: 1017 AIFFVPVFFVVIRR 1030 Score = 83.0 bits (205), Expect = 4e-18 Identities = 101/526 (19%), Positives = 197/526 (37%), Gaps = 58/526 (11%) Query: 534 KLAIVGVVYICLIVVTGGVA-KILPSGFVPMEDKKAFMVDIQLPDGASLNRTEDVMRELV 592 + I V ++++ G +A LP P A V P GA +D + +++ Sbjct: 7 RRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYP-GADAQTVQDTVTQVI 65 Query: 593 ELTLAEPGVENVIHASGFSILTGSVSSNGGLMIVTLSTWSERESPDMVESAIVAKLQAKY 652 E + G++N+++ S S S + G + +TL T+ PD+ + + KLQ Sbjct: 66 EQNMN--GIDNLMYMS-------STSDSAGSVTITL-TFQSGTDPDIAQVQVQNKLQLAT 115 Query: 653 AANPAVKAMAFSLPPIPGVGSVGGFEFVL---QDTQGRTPQEL----ASVMRALIMKANE 705 P I S + V D G T ++ AS ++ + + N Sbjct: 116 PLLPQ----EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNG 171 Query: 706 QPEIAMAFSNFRADVPQMFVDVDRDKAKALGISLNEIFSTMQT----MLGSMYVNDFNRF 761 ++ + + + M + +D D ++ ++ + ++ + Sbjct: 172 VGDVQLFGAQY-----AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALP 226 Query: 762 GKVFRVILQAESEYRNSDRDISRFYVRSNT-GEMVPLSTLVTVTPILGPDVMNNYNMFSS 820 G+ + A++ ++ + + + +R N+ G +V L + V LG + NYN Sbjct: 227 GQQLNASIIAQTRFK-NPEEFGKVTLRVNSDGSVVRLKDVARVE--LGGE---NYN--VI 278 Query: 821 TTINGFPAPGFS-----------SGDAITAMERAANESLPAGYTFEWTGQTYQEIKAGNL 869 ING PA G + AI A P G + T ++ Sbjct: 279 ARINGKPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIH 338 Query: 870 A---PLIFSLALVFTYLFLVAQYESWTIPFAVILAVPIAVLGAFLNILLVGSDLNLYAQI 926 L ++ LVF ++L ++ +AVP+ +LG F + G +N Sbjct: 339 EVVKTLFEAIMLVFLVMYLF--LQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMF 396 Query: 927 GLVLLIGLACKNAILIVE-FAKQLHEEGKSILDAAQTAARLRFRAVLMTAFSFLLGVLPL 985 G+VL IGL +AI++VE + + E+ +A + + A++ A +P+ Sbjct: 397 GMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPM 456 Query: 986 VIATGAGAGSRRALGYSVFGGMLAATIVGTLLVPVFYVIMQKMREK 1031 G+ R ++ M + +V +L P + K Sbjct: 457 AFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSA 502
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 775 bits (2004), Expect = 0.0 Identities = 308/1032 (29%), Positives = 515/1032 (49%), Gaps = 28/1032 (2%) Query: 3 LSDVSVKRPVVAIVLSLLLCVFGAVSFSKLAVREMPDVESPVVTVMTTYEGASATIMESQ 62 +++ ++RP+ A VL+++L + GA++ +L V + P + P V+V Y GA A ++ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 63 ITTTLEGELTGISGVDQIQSIT-RNGMSRITVTFLLGWDLTEGVSDVRDAVARAQRRLPD 121 +T +E + GI + + S + G IT+TF G D V++ + A LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 122 EAKDPIVSKDNGSGEPSVYVNLSSSVMDRTQ--LTDYAQRVLEDRFSLISGVSSVSISGG 179 E + +S + S + S TQ ++DY ++D S ++GV V + G Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 180 LYKVMYVQLNPELMAGRNITTRDIVNVLNKENVETPGGEVRNDTTV------MAVRTARL 233 Y + + L+ +L+ +T D++N L +N + G++ + ++ Sbjct: 181 QYAMR-IWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 234 YQSPEDFNYLVLRTAADGSQVYLKDVANVFIGAENENSTFKSDGVVNISLGVVSQSDANP 293 +++PE+F + LR +DGS V LKDVA V +G EN N + +G LG+ + AN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 294 LEVAQDVHKEVELIQKFLPDGTKLIVDYDSTVFIDRSIDEVFSTLAVTALLVILVLYIFI 353 L+ A+ + ++ +Q F P G K++ YD+T F+ SI EV TL +LV LV+Y+F+ Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 354 GQARATLIPAVTVPVSLISAFIAANVFGYSINLLTLMALILSIGLVVDDAIVVVENIFHH 413 RATLIP + VPV L+ F FGYSIN LT+ ++L+IGL+VDDAIVVVEN+ Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 414 I-EKGEPPILAAYNGTREVGFAVIATTAVLVMVFLPISFMEGMVGLLFTEFSVMLAVSVL 472 + E PP A ++ A++ VL VF+P++F G G ++ +FS+ + ++ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 473 FSSLIALTLTPVLGSKLLKANVK-----PNRFNLWVESGFSKLEHAYRNMVAKAVTFRVA 527 S L+AL LTP L + LLK F W + F + Y N V K + Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 528 SPLVIIACILGSAWLMQQVPAQLAPQEDRGVIFAFIKGAEGTSYNRMAANMEIAEKKLMP 587 L+ + G L ++P+ P+ED+GV I+ G + R ++ + Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 588 LLGQGVVKSFSIQAPAFGGRAGDQTGFVIIQLEDWDERTINAQQALGVVAKA---LKGIP 644 V F++ +F G+ G + L+ W+ER + A V+ +A L I Sbjct: 600 NEKANVESVFTVNGFSFSGQ-AQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIR 658 Query: 645 DVMVRP--LLPGFRGGSSEPVQFVL---GGSDYEELFKWA-KLLEEEALYSPIFESPEID 698 D V P + G++ F L G ++ L + +LL A + S + Sbjct: 659 DGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPN 718 Query: 699 YQETTPELVVTVDKERAAELGISVAEVSETLEIMLGGRSETTFVERGEEYDVYLRGDENS 758 E T + + VD+E+A LG+S++++++T+ LGG F++RG +Y++ D Sbjct: 719 GLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKF 778 Query: 759 FSNVADLSQIYMRSNKGELITLDTITHIEEVASAQKLSHNNKQKSITLKANLGKGYTLGE 818 D+ ++Y+RS GE++ T V + +L N S+ ++ G + G+ Sbjct: 779 RMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGD 838 Query: 819 ALDFLDEKAIEMLPSDISVAYTGESKDFKENQSSIFIVFGLALLVAYLVLAAQFESFINP 878 A+ + E LP+ I +TG S + + + + ++ +V +L LAA +ES+ P Sbjct: 839 AMALM-ENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIP 897 Query: 879 LVVMFTVPMGVFGGFLGLYLTGQGLNIYSQIGMIMLIGMVTKNGILIVEFANQLRDK-GL 937 + VM VP+G+ G L L Q ++Y +G++ IG+ KN ILIVEFA L +K G Sbjct: 898 VSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGK 957 Query: 938 EIEQAIIDASVRRLRPILMTAFTTLIGAIPLILSTGAGSESRIAVGTVVFFGMAFATFVT 997 + +A + A RLRPILMT+ ++G +PL +S GAGS ++ AVG V GM AT + Sbjct: 958 GVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLA 1017 Query: 998 LLVIPAMYRLIS 1009 + +P + +I Sbjct: 1018 IFFVPVFFVVIR 1029
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 39.0 bits (91), Expect = 2e-05 Identities = 47/254 (18%), Positives = 86/254 (33%), Gaps = 33/254 (12%) Query: 47 EQHELSQSLSLIGKLDAEQSVFIAPQIAGKIKSIRVSTEQEIDQGQLL------------ 94 Q++ Q + K AE+ +A +I RV + D LL Sbjct: 198 WQNQKYQKELNLDKKRAERLTVLA-RINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLE 256 Query: 95 VQLDDAKAQAALAEAAAYLAD---EKRKLKEFLKLIDQNAITKTEIDAQKASVDMA--NA 149 + +A L + L E KE +L+ Q + ++ + ++ Sbjct: 257 QENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTL 316 Query: 150 RLAAAQADLDYHYLSAPFSGTT-GLIDFSRGKMVTAGTELLTL-DDLSSMRLDLQVPEHY 207 LA + + AP S L + G +VT L+ + + ++ + V Sbjct: 317 ELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKD 376 Query: 208 LSQLSVGMKVSAKSRAWPNQ---VFIGKVLAID-SRVNQDTLNL--RVRVQFDNPT---- 257 + ++VG K A+P +GKV I+ + L L V + + Sbjct: 377 IGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCLSTG 436 Query: 258 ---QQLKPGMMMSA 268 L GM ++A Sbjct: 437 NKNIPLSSGMAVTA 450 Score = 37.5 bits (87), Expect = 6e-05 Identities = 25/159 (15%), Positives = 50/159 (31%), Gaps = 26/159 (16%) Query: 10 IMLVVAGAISYSSFSEAKRTDSKDRPVRTVPVVTGIVEQHELSQSLSLIGKLDAEQSVFI 69 IM + A S V V G + + +S I Sbjct: 64 IMGFLVIAFILSVLG----------QVEIVATANGKL--------------THSGRSKEI 99 Query: 70 APQIAGKIKSIRVSTEQEIDQGQLLVQLDDAKAQAALAEAAAYLADEKRKLKEFLKLIDQ 129 P +K I V + + +G +L++L A+A + + L +L++ I Sbjct: 100 KPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQA--RLEQTRYQILS 157 Query: 130 NAITKTEIDAQKASVDMANARLAAAQADLDYHYLSAPFS 168 +I ++ K + ++ + + FS Sbjct: 158 RSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFS 196
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 360 bits (925), Expect = e-110 Identities = 205/1050 (19%), Positives = 429/1050 (40%), Gaps = 60/1050 (5%) Query: 1 MVKSLVENGRLISLIIALLIVAGFGAISSLPRMEDPEITNRFASVITHYPGASAERVEAL 60 M + ++ +L++AG AI LP + P I SV +YPGA A+ V+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTEVLESELRRLEELKLVQSTS-RPGISVIQLELKDSVVETAPVWSR--ARDLIADAKAL 117 VT+V+E + ++ L + STS G I L + T P ++ ++ + A L Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQS---GTDPDIAQVQVQNKLQLATPL 117 Query: 118 LPVSAQTPTL-DDQLGYANTAILGIVWRGGGEVRTDMLNRYAKELQSQLRLLSGTDFVNL 176 LP Q + ++ + + G V G + D+ + A ++ L L+G V L Sbjct: 118 LPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQL 177 Query: 177 YGQPTEEILVQLDGHKVNQLALSAQSIAQILQNADAKVSAGEINND------NFRALIEV 230 +G + + LD +N+ L+ + L+ + +++AG++ A I Sbjct: 178 FGAQ-YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIA 236 Query: 231 SGELDSISRIAQVPLKVTEDGQIIRLADIAHISRQPKEPANSIALIDQQQGVMVAARMLS 290 + +V L+V DG ++RL D+A + E N IA I+ + + ++ + Sbjct: 237 QTRFKNPEEFGKVTLRVNSDGSVVRLKDVARV-ELGGENYNVIARINGKPAAGLGIKLAT 295 Query: 291 NTRVDLWLEQVKHSVDQLQTSIPANIEIEWLFDQEGYTTERLSDLVGSLLLG-FLIILAV 349 + +K + +LQ P +++ + +D + + ++V +L L+ L + Sbjct: 296 GANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVM 355 Query: 350 LMLTLGLRNAVIVALSLPLTALFTLACMKYIGLPIHQMSVTGLVVALGIMVDNAIVIVDA 409 + +R +I +++P+ L T A + G I+ +++ G+V+A+G++VD+AIV+V+ Sbjct: 356 YLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVEN 415 Query: 410 ISQRRQK-GMDRLDAVKQTLEHLWLPLAGSTITTMLAFAPIVLMPGAAGEFVGGIAISVM 468 + + + + +A ++++ + L G + F P+ G+ G +I+++ Sbjct: 416 VERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIV 475 Query: 469 FALLGSFIISHTIIAGLAGRFGVDGKGTHWYHRGINLPFMSHAFRQTLSLA-------LS 521 A+ S +++ + L H ++G + + F +++ L Sbjct: 476 SAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILG 535 Query: 522 RPLLAAVIIGVLPVMGFIAAGKMTEQFFPPSDRDMFQIEVYLAPQASISNTRAQVEKI-- 579 +I ++ + ++ F P D+ +F + L A+ T+ ++++ Sbjct: 536 STGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTD 595 Query: 580 DAKLRQTDGVTRIDWVVGGNAPSFYYNLLQRQQGASHYAQAMVKARDFA-----SANQLI 634 + V + V G + Q + A +K + SA +I Sbjct: 596 YYLKNEKANVESVFTVNGFSFSG--------QAQNAGMAFVSLKPWEERNGDENSAEAVI 647 Query: 635 PQLQMTLDKQFPGAQII------VRKLEQGPPFNAPVEVRIFGPNLDQLKLLGEQV-RKA 687 + +M L + +I + +L F+ + + G D L Q+ A Sbjct: 648 HRAKMEL-GKIRDGFVIPFNMPAIVELGTATGFDFELIDQ-AGLGHDALTQARNQLLGMA 705 Query: 688 LSDTQNVIHTRATLSAGSPKVWLQINEDASLISGLSLTDIAKQIEMATTGINGGSILEQT 747 +++ R + + L+++++ + G+SL+DI + I A G +++ Sbjct: 706 AQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRG 765 Query: 748 ESLPVRVRLSDSIREQQTKLSAITLVSGQGTGIPLSAISSSQIEVSRGAIPRRDGQRVNV 807 + V+ R + + + S G +P SA ++S + R +G Sbjct: 766 RVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSME 825 Query: 808 IEAYITSGVLPQTVVDNVSDKLSAIELPSGYRVELGGESAKRNEAIGNLMSNLVLVITLL 867 I+ G + + + S +LP+G + G S + + + + + ++ Sbjct: 826 IQGEAAPGTSSGDAMALMENLAS--KLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVV 883 Query: 868 LATVVLSFNSFRLTGIILFSAIQSAGLGLLAVYTFGYPFGFTVIIGLLGLMGLAINAAIV 927 + + S+ + ++ LLA F ++GLL +GL+ AI+ Sbjct: 884 FLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAIL 943 Query: 928 ILAELEEIPATRNGDTQLIVELVTRCG----RHIGSTTITTIGGFLPLII---AGGGFWP 980 I+ +++ + G +VE R I T++ I G LPL I AG G Sbjct: 944 IVEFAKDLME-KEGKG--VVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQN 1000 Query: 981 PFAIAIAGGTLLTTLLSLVWVPTMYHLIMR 1010 I + GG + TLL++ +VP + +I R Sbjct: 1001 AVGIGVMGGMVSATLLAIFFVPVFFVVIRR 1030
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 48.7 bits (116), Expect = 2e-08 Identities = 29/210 (13%), Positives = 74/210 (35%), Gaps = 40/210 (19%) Query: 109 ELDASLAQNKADLDLAKATLGRSLELQQQGYVSEQQLDELKGQLSSLLAAKNR------- 161 E + + +L + K+ L +++ + ++++ + + + K R Sbjct: 256 EQENKYVEAVNELRVYKSQLE---QIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIG 312 Query: 162 -LSASLLANQLKIEKSDLLAPFDGVISKRS-HNLGEVIGVGSPVYTII-EQNNIQAYVGV 218 L+ L N+ + + S + AP + + H G V+ + I+ E + ++ V Sbjct: 313 LLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALV 372 Query: 219 PVQIANNLTTGQSVDLRV---------------------RQQD------YHASIAGIGAE 251 + + GQ+ ++V +D ++ I+ Sbjct: 373 QNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENC 432 Query: 252 LNPVTRTVELRLTLPDDANVINGELSYLNY 281 L+ + + L + A + G S ++Y Sbjct: 433 LSTGNKNIPLSSGMAVTAEIKTGMRSVISY 462 Score = 38.3 bits (89), Expect = 5e-05 Identities = 22/106 (20%), Positives = 42/106 (39%), Gaps = 7/106 (6%) Query: 76 GKIKTLAVDSGDRVKQGQLLAKLDTRLLMAEKNELDASLAQNKADLDLAKATLGRSLELQ 135 +K + V G+ V++G +L KL A+ + +SL Q + + L RS+EL Sbjct: 105 SIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQ-TRYQILSRSIELN 163 Query: 136 QQGYVSEQQLDELKGQLSSLLAAKNRLSA-SLLANQLKIEKSDLLA 180 + +L ++ + L SL+ Q ++ Sbjct: 164 K-----LPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQ 204
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 78.1 bits (192), Expect = 4e-20 Identities = 39/204 (19%), Positives = 65/204 (31%), Gaps = 5/204 (2%) Query: 1 MNSPVLSRSEQKREQILQAAKDLFCEQGFPNTSMDEVAKLAGVSKQTVYSHFGCKDDLFV 60 M +++ R+ IL A LF +QG +TS+ E+AK AGV++ +Y HF K DLF Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 A--SIESKCLVHGVNQEVFSDPTMPEDSLLLFAKHFGEVITSPEAVTVFKACVAQADSHP 118 + + + P P L H E + E + + Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 119 ---ELSELFYSAGPQHILGLLRDYLTRVSELGVYHFANPHHCAVRLCLMIFGEMRMRLDL 175 + + + L E + A + + Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180 Query: 176 GLDVSDLLDTREQYINETVEMFLR 199 DL Y+ +EM+L Sbjct: 181 APQSFDLKKEARDYVAILLEMYLL 204
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 78.3 bits (193), Expect = 2e-18 Identities = 41/245 (16%), Positives = 90/245 (36%), Gaps = 54/245 (22%) Query: 6 SILITGGTGSFGRMYTRTILERY-----------------KPKRLIIFSRDELKQYEMQQ 48 L+TG G G ++ +LE K RL + ++ + ++ Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHK--- 58 Query: 49 EFNEPCMRYFIGDVRDGDRLKQAFRDVDF--VIHAAALKQVPAAEYNPMECIKTNIHGAE 106 D+ D + + F F V + V + NP +N+ G Sbjct: 59 -----------IDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFL 107 Query: 107 NVIKAAIENGVEKVIALST---------------DKAANPINLYGATKLASDKLFVAANN 151 N+++ N ++ ++ S+ D +P++LY ATK A++ + ++ Sbjct: 108 NILEGCRHNKIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSH 167 Query: 152 IVGEGRTRFSAVRYGNVVGSRGS---VVPLFKAIVARGETCLPITHEEMTRFWISLQDGV 208 + G + +R+ V G G + F + G++ + +M R + + D Sbjct: 168 LYG---LPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIA 224 Query: 209 DFVLK 213 + +++ Sbjct: 225 EAIIR 229
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 63.7 bits (155), Expect = 2e-13 Identities = 23/128 (17%), Positives = 54/128 (42%), Gaps = 12/128 (9%) Query: 180 HIMVIDDSSVARKQIIRALTSLDLQIDTAKDGKEALEKLRAMSAELEDVSTEIPLIISDI 239 I+V DD + R + +AL+ + + + A + L+++D+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGD---------LVVTDV 55 Query: 240 EMPEMDGYTLTAEIRDDPKLKNIKVVLHTSLSGVFNQAMVQKVGANDFIAK-FNPDELAA 298 MP+ + + L I+ ++ V++ ++ + + GA D++ K F+ EL Sbjct: 56 VMPDENAFDLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIG 113 Query: 299 AVNKHLSL 306 + + L+ Sbjct: 114 IIGRALAE 121
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 33.8 bits (77), Expect = 2e-04 Identities = 11/38 (28%), Positives = 18/38 (47%) Query: 99 NVNVMEEMANMISASRSYQMNVQVTEAAKSMLQQTLRI 136 VN+ EE N+ + Y N QV + A ++ + I Sbjct: 508 GVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545 Score = 26.5 bits (58), Expect = 0.046 Identities = 10/25 (40%), Positives = 17/25 (68%) Query: 8 NVAGSGMSAQSVRLNTTASNIANAD 32 N A SG++A LNT ++NI++ + Sbjct: 5 NNAMSGLNAAQAALNTASNNISSYN 29
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 41.5 bits (97), Expect = 5e-06 Identities = 28/94 (29%), Positives = 41/94 (43%), Gaps = 7/94 (7%) Query: 2 SFNIALSGISSAQKDLNTTANNIANVNTTGFKESRAEFADVYASSIFANSKTTVGGGVAT 61 N A+SG+++AQ LNT +NNI++ N G+ A S++ A VG GV Sbjct: 3 LINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQA-NSTLGAGG--WVGNGVYV 59 Query: 62 SQVAQQFHQGSMAFTNNSLDMAINGGGFFVTSSE 95 S V +++ F N L A E Sbjct: 60 SGVQREYDA----FITNQLRAAQTQSSGLTARYE 89 Score = 38.0 bits (88), Expect = 6e-05 Identities = 12/49 (24%), Positives = 24/49 (48%) Query: 405 SIRSSALEQSNVDLTTELVDLISAQRNFQANSRTLEVNNTLQQTILQIR 453 + + S V+L E +L Q+ + AN++ L+ N + ++ IR Sbjct: 498 QLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR 546
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 29.2 bits (65), Expect = 0.018 Identities = 10/34 (29%), Positives = 18/34 (52%) Query: 4 LLYVAMSGAKQNMNSLAVSANNLANANTDGFKSS 37 L+ AMSG +L ++NN+++ N G+ Sbjct: 3 LINNAMSGLNAAQAALNTASNNISSYNVAGYTRQ 36
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 43.4 bits (102), Expect = 5e-07 Identities = 19/117 (16%), Positives = 39/117 (33%), Gaps = 4/117 (3%) Query: 147 ATSITVSAEGEVSVKTPGNAENQVVGQLAIADFINPSGLDPMGQNLYLETG---ASGTPI 203 I +++E + N + + Q + +L + G A+ Sbjct: 429 EAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGNKTATLKTS 488 Query: 204 QGTASLDGMGAIRQGALETSNVNVTEELVNLIESQRIYEMNSKVISAVDQMLSYVNQ 260 T + + S VN+ EE NL Q+ Y N++V+ + + + Sbjct: 489 SATQGNV-VTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALIN 544 Score = 35.3 bits (81), Expect = 2e-04 Identities = 8/36 (22%), Positives = 21/36 (58%) Query: 5 LWISKTGLDAQQTDISVISNNVANASTVGFKKSRAV 40 + + +GL+A Q ++ SNN+++ + G+ + + Sbjct: 4 INNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTI 39
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 144 bits (365), Expect = 3e-45 Identities = 73/219 (33%), Positives = 106/219 (48%), Gaps = 15/219 (6%) Query: 8 LFMAALSGCNSTNGKPIADDPYYAPVYPEAPPTKIAATGSMYQDSQ-----ASSLYSDIK 62 L + +L+GC P+ A P P A GS++Q +Q L+ D + Sbjct: 14 LLVLSLTGCAWIPSTPLVQGATSAQPVPGPTP---VANGSIFQSAQPINYGYQPLFEDRR 70 Query: 63 ALKVGDIITVYLMEQTQAKKSANNEISK----GTDLSLDPIYAGGGNVTIGGNPIDLRYK 118 +GD +T+ L E A KS++ S+ P Y G G D+ Sbjct: 71 PRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLF---GNARADVEAS 127 Query: 119 DSMNTKRESDADQSNSLSGSISANVMQVLNNGNLVIRGEKWISINNGDEFVRITGIVRAQ 178 + A+ SN+ SG+++ V QVL NGNL + GEK I+IN G EF+R +G+V + Sbjct: 128 GGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRFSGVVNPR 187 Query: 179 DIRPDNTIDSQRVANARIQYSGTGTFAEVQKVGWLASFF 217 I NT+ S +VA+ARI+Y G G E Q +GWL FF Sbjct: 188 TISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFF 226
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 386 bits (994), Expect = e-136 Identities = 166/367 (45%), Positives = 226/367 (61%), Gaps = 14/367 (3%) Query: 6 LVLLCAMLVLTTPVHAQ--RIKDIANVQGVRSNQLIGYGLVVGLPGTGEKTR---YTEQT 60 LV + T P A RIKDIA++Q R NQLIGYGLVVGL GTG+ R +TEQ+ Sbjct: 11 LVFSALPFLSTPPAQADTSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFTEQS 70 Query: 61 FKTMLKNFGINLPDNFRPKIKNIAVVAVSADMPPFIKPGQTLDVTVSSLGEAKSLRGGML 120 + ML+N GI + KNIA V V+A++PPF PG +DVTVSSLG+A SLRGG L Sbjct: 71 MRAMLQNLGITTQGG-QSNAKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRGGNL 129 Query: 121 LQTFLKGVDGNVYAIAQGSMVVSGFSAEGMDGSKVIQNTPTVGRIPNGAIIERTVATPFS 180 + T L G DG +YA+AQG+++V+GFSA+G D + + Q T R+PNGAIIER + + F Sbjct: 130 IMTSLSGADGQIYAVAQGALIVNGFSAQG-DAATLTQGVTTSARVPNGAIIERELPSKFK 188 Query: 181 TGDHLTFNLRRADFSTAKRLADSINDL----LGPGMARPLDAASVQVSAPRDVSQRVSFL 236 +L LR DFSTA R+AD +N G +A P D+ + V PR V+ + Sbjct: 189 DSVNLVLQLRNPDFSTAVRVADVVNAFARARYGDPIAEPRDSQEIAVQKPR-VADLTRLM 247 Query: 237 ATLENIEVEPAAESAKVIVNSRTGTIVVGQNVKLLPAAVTHGGLTVTIAEATQVSQPNPF 296 A +EN+ VE AKV++N RTGTIV+G +V++ AV++G LTV + E+ QV QP PF Sbjct: 248 AEIENLTVETDTP-AKVVINERTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQPAPF 306 Query: 297 GNGQTVVTTDSTIDVAEEDSRMFMFNPGTTLDELVRAVNLVGAAPSDVLAILEALKMAGA 356 GQT V + I +E S++ + G L LV +N +G ++AIL+ +K AGA Sbjct: 307 SRGQTAVQPQTDIMAMQEGSKVAIVE-GPDLRTLVAGLNSIGLKADGIIAILQGIKSAGA 365 Query: 357 LHGELII 363 L EL++ Sbjct: 366 LQAELVL 372
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 196 bits (499), Expect = 2e-62 Identities = 106/349 (30%), Positives = 173/349 (49%), Gaps = 63/349 (18%) Query: 7 ASQFLDLGGLDSLRSRAQKDETSALKEVAQQFEGIFVQMLMKSMRDANAVFESDSPMNSQ 66 AS D L+ L+++A +D + ++ VA+Q EG+FVQM++KSMRDA D +S+ Sbjct: 9 ASAAWDAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALP---KDGLFSSE 65 Query: 67 YTKFYEQMHDQQMSLNLSGEGMLGLADLMVQQLDPANSPMTPASVLRGDINGGSKAAALT 126 +T+ Y M+DQQ++ ++ LGLA++MV+Q+ P Sbjct: 66 HTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQ----------------------P 103 Query: 127 MGKPDTLQMPTSRVSGSDAMAAQAAPFIAQSQIQAQSQAQVTAAQTALTSSAQSQTLDSV 186 + + T P F ++ ++ Q+QA Q A+ + Sbjct: 104 LPEESTPAAPMK--------------FPLETVVRYQNQALSQLVQKAVPRNYDDSL---- 145 Query: 187 LSGKVLPSAAVTADKSQANFTSQDEFVARLYPHAQKAAQTLGTTPELLIAQSALETGWGQ 246 S+ F+A+L AQ A+Q G L++AQ+ALE+GWGQ Sbjct: 146 ------------------PGDSKA-FLAQLSLPAQLASQQSGVPHHLILAQAALESGWGQ 186 Query: 247 KMVKGHQGQQSNNLFNIKADNRWQGEHASVSTLEYEQGIAVKQRANFRVYDDIGQSFNDF 306 + ++ G+ S NLF +KA W+G ++T EYE G A K +A FRVY ++ +D+ Sbjct: 187 RQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYLEALSDY 246 Query: 307 VSFVSNGERYQDAMKQAANPQAFIRSLQDAGYATDPKYADKVIQVMKTI 355 V ++ RY A+ AA+ + ++LQDAGYATDP YA K+ +++ + Sbjct: 247 VGLLTRNPRYA-AVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQM 294
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 224 bits (572), Expect = 1e-67 Identities = 121/454 (26%), Positives = 199/454 (43%), Gaps = 19/454 (4%) Query: 4 DLMNIARTGVLASQSQLAITSNNIANANTAGYNRQVVSQSALDSQRMGNEFYGAGTYVSD 63 L+N A +G+ A+Q+ L SNNI++ N AGY RQ + +S + G G YVS Sbjct: 2 SLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVSG 61 Query: 64 VKRVYNDYATRELRIGSTAVSESQTTFSKMSQLDQLFSQMGKAVPQGLNDFFASMNALAD 123 V+R Y+ + T +LR T S + +MS++D + S ++ + DFF S+ L Sbjct: 62 VQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLVS 121 Query: 124 IPNDMGLRGSFLTSANQLANSVNQMQSHLDSQMTQTNDQISAVTDRINEISNELGSINRE 183 D R + + + L N +L Q Q N I A D+IN + ++ S+N + Sbjct: 122 NAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLNDQ 181 Query: 184 LMKSQGQDM-----QLLDKQDALILELSEYASVNVIPLESGAKSIMLGGSMMLVSGEMSM 238 + + G LLD++D L+ EL++ V V + G +I + LV G + Sbjct: 182 ISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTAR 241 Query: 239 QVGTAPGDPYPNELQITAQSGS--KSMIVDASKMGGQLGALVNYRDETLIPSQMELGQFA 296 Q+ P P+ + G+ I + G LG ++ +R + L ++ LGQ A Sbjct: 242 QLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQLA 301 Query: 297 LGVSDAFNQAQAQGFDLNGQVGANIFTDINDPSMQLGRVGALSSNTGTANLSVNIDDVGS 356 L ++AFN GFD NG G + F + V + N G + + D + Sbjct: 302 LAFAEAFNTQHKAGFDANGDAGEDFFA------IGKPAVLQNTKNKGDVAIGATVTDASA 355 Query: 357 LTGSSYELKF--TAPSTYELKDAVSGNITPLTLNGTKLEGANGFSINIDAGALASGDTFE 414 + + Y++ F L + +TP +G G A D+F Sbjct: 356 VLATDYKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFT----GTPAVNDSFT 411 Query: 415 IRPTSSAAVSLSVEMTDAKGIAAAGAKITADAAN 448 ++P S A V++ V +TD IA A + D+ N Sbjct: 412 LKPVSDAIVNMDVLITDEAKIAMASEEDAGDSDN 445 Score = 95.8 bits (238), Expect = 6e-23 Identities = 38/104 (36%), Positives = 58/104 (55%) Query: 533 AEGDNTNMVSMAKLSEAKLMNGGKTTLTDVFENTTIDVGSKTKSAEISMGSAEAIYKQAY 592 + DN N ++ L GG + D + + D+G+KT + + S + + Q Sbjct: 441 GDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGNKTATLKTSSATQGNVVTQLS 500 Query: 593 TRVQSVSGVNLDEEAANLMRFQQSYQASARIMTTANEIFNTLFS 636 + QS+SGVNLDEE NL RFQQ Y A+A+++ TAN IF+ L + Sbjct: 501 NQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALIN 544
>FLAGELLIN#Flagellin signature. Length = 507 Score = 50.8 bits (121), Expect = 5e-09 Identities = 37/145 (25%), Positives = 66/145 (45%), Gaps = 4/145 (2%) Query: 1 MRIST--AQMFHQNINSVTQKQSQTSQIIEQLSTGKRVNTAGDDPVAAAGINNLNQKNSV 58 I+T + QN + +Q ++ E+LS+G R+N+A DD A N Sbjct: 2 QVINTNSLSLLTQNNLNKSQSSLSSAI--ERLSSGLRINSAKDDAAGQAIANRFTSNIKG 59 Query: 59 VDQFLKNIDYAKNRLSISESKLGSAATLASSVREQVLRAVNGSLTDSDRQTVADEMRGSL 118 + Q +N + + +E L VRE ++A NG+ +DSD +++ DE++ L Sbjct: 60 LTQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRL 119 Query: 119 EELMAIANSKDESGNYLFGGFNTGS 143 EE+ ++N +G + N Sbjct: 120 EEIDRVSNQTQFNGVKVLSQDNQMK 144
>FLAGELLIN#Flagellin signature. Length = 507 Score = 135 bits (341), Expect = 9e-39 Identities = 95/271 (35%), Positives = 130/271 (47%), Gaps = 10/271 (3%) Query: 2 AITVNTNVTSMKAQKNLNTSSQGLATSMERLSSGLRINSAKDDAAGLAISNRLDSQVRGL 61 A +NTN S+ Q NLN S L++++ERLSSGLRINSAKDDAAG AI+NR S ++GL Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 DVGMRNANDAISIAQIAEGAMQEQTNMLQRMRDLTIQASNGANSTDDIASIQKEIDALAT 121 RNAND ISIAQ EGA+ E N LQR+R+L++QA+NG NS D+ SIQ EI Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 EITSIGNSTAFGNTKLLDGGFSAGKSFQVGHQKGEDISVKVSKVNSSSLAVGGL------ 175 EI + N T F K+L QVG GE I++ + K++ SL + G Sbjct: 121 EIDRVSNQTQFNGVKVLSQDNQ--MKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPK 178 Query: 176 --TLTNSANRQSALTKIDAAIKTIDTQRADLGAVQNRLAHNISNSANTQANVADAKSRIV 233 T+ + + +T D + R D+ + + A Sbjct: 179 EATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTT 238 Query: 234 DVDFAKETATMTKNQVLQQTGSAMLAQANQL 264 D + K + A A + Sbjct: 239 DDAENNTAVDLFKTTKSTAGTAEAKAIAGAI 269 Score = 85.1 bits (210), Expect = 7e-21 Identities = 57/213 (26%), Positives = 94/213 (44%), Gaps = 4/213 (1%) Query: 60 GLDVGMRNANDAISIAQIAEGAMQEQTNMLQRMRDLTIQASNGANSTDDIASIQKEIDAL 119 + + +++A I GA LQ +++ NG + DD + + Sbjct: 298 KVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSD 357 Query: 120 ATEITSIGNSTAFGNTKLLDGGFSAGKSFQVGHQKGEDISVKVSKVNSSSLAVGGLTLTN 179 ++ + +AG + + + S + Sbjct: 358 LEANNAVKGESKITVNGAEYTANAAGDKVTLAGK----TMFIDKTASGVSTLINEDAAAA 413 Query: 180 SANRQSALTKIDAAIKTIDTQRADLGAVQNRLAHNISNSANTQANVADAKSRIVDVDFAK 239 + + L ID+A+ +D R+ LGA+QNR I+N NT N+ A+SRI D D+A Sbjct: 414 KKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYAT 473 Query: 240 ETATMTKNQVLQQTGSAMLAQANQLPQVALSLL 272 E + M+K Q+LQQ G+++LAQANQ+PQ LSLL Sbjct: 474 EVSNMSKAQILQQAGTSVLAQANQVPQNVLSLL 506
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 264 bits (676), Expect = 1e-91 Identities = 125/246 (50%), Positives = 181/246 (73%), Gaps = 3/246 (1%) Query: 2 MKWILLLAGLALTFMAPTALAENGILPAVTVSTGADGSTQYSVTMQILLLMTALSFIPAM 61 M+ +L +A + L + P A A+ LP +T G +S+ +Q L+ +T+L+FIPA+ Sbjct: 1 MRRLLSVAPVLLWLITPLAFAQ---LPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAI 57 Query: 62 VIMLTSFTRIIVVLSILRQAIGLQQTPSNQVLIGISMFMTFFIMSPVFDKIYVQAVQPYI 121 ++M+TSFTRII+V +LR A+G P NQVL+G+++F+TFFIMSPV DKIYV A QP+ Sbjct: 58 LLMMTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFS 117 Query: 122 EQGMPLQDAFTTGQGPLKDFMLAQTRNSDLNTFIEISGYQNINEPEDAPMTVIIPAFITS 181 E+ + +Q+A G PL++FML QTR +DL F ++ + PE PM +++PA++TS Sbjct: 118 EEKISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTS 177 Query: 182 ELKTAFQIGFMLFVPFLVLDLVVASILMAMGMMMLSPMIVSLPFKIMLFVLVDGWSLVMG 241 ELKTAFQIGF +F+PFL++DLV+AS+LMA+GMMM+ P ++LPFK+MLFVLVDGW L++G Sbjct: 178 ELKTAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVG 237 Query: 242 TLANSF 247 +LA SF Sbjct: 238 SLAQSF 243
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 42.4 bits (100), Expect = 7e-09 Identities = 23/81 (28%), Positives = 44/81 (54%) Query: 4 EALIDIFREALAVIVIIVSMIIVPGLIIGLVVAVFQAATSINEQTLSFLPRLLTTLLALM 63 + L+ +AL +++I+ + IIGL+V +FQ T + EQTL F +LL L L Sbjct: 2 DDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLF 61 Query: 64 LMGHMLVQMMMDFFFQMVDMI 84 L+ ++++ + Q++ + Sbjct: 62 LLSGWYGEVLLSYGRQVIFLA 82
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 121 bits (304), Expect = 3e-35 Identities = 80/243 (32%), Positives = 139/243 (57%), Gaps = 1/243 (0%) Query: 15 YLWPLTRISSMFMVMAVFGATTTPTRVRLLLSVAVTVAVAPVLPAMPTIDLFSLSAAFVT 74 Y WPL R+ ++ + + P RV+L L++ +T A+AP LPA +FS A ++ Sbjct: 16 YFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPANDVP-VFSFFALWLA 74 Query: 75 AQQIIIGVAMGFATLLLMQTFVLTGQIIGMQTSLGFASMVDPSSGQQTPVIGNFFLLLTT 134 QQI+IG+A+GF G+IIG+Q L FA+ VDP+S PV+ +L Sbjct: 75 VQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHLNMPVLARIMDMLAL 134 Query: 135 VIFLAVDGHLLLIKMVIASFDSIPVSMQGLSLVSYRLFTEFVGYMFGAALTMSLSAIVAL 194 ++FL +GHL LI +++ +F ++P+ + L+ ++ T+ +F L ++L I L Sbjct: 135 LLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLIFLNGLMLALPLITLL 194 Query: 195 LTINLSFGVMTRASPQLNIFSIGFPVTMIAGLFILWLTLSPIMTHFDEVWREVQLLLCNV 254 LT+NL+ G++ R +PQL+IF IGFP+T+ G+ ++ + I + ++ E+ LL ++ Sbjct: 195 LTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFCEHLFSEIFNLLADI 254 Query: 255 LEL 257 + Sbjct: 255 ISE 257
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 332 bits (853), Expect = e-115 Identities = 106/363 (29%), Positives = 181/363 (49%), Gaps = 23/363 (6%) Query: 7 SQEKTEEATSRKLQQAKDKGQVARSKELGTSAVLIAASVGLLMTGPDIAQAMHNIMTKLF 66 S EKTE+ T +K++ A+ KGQVA+SKE+ ++A+++A S L+ + +KL Sbjct: 2 SGEKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFE----HFSKLM 57 Query: 67 TMSRDEIFD------TKQMMNVWGVIGTELALPLMGFIVFLALIAFAGNVALGGISFSVK 120 + ++ + + + NV L PL+ +A+ + +V G S + Sbjct: 58 LIPAEQSYLPFSQALSYVVDNVLLEFFY-LCFPLLTVAALMAIAS---HVVQYGFLISGE 113 Query: 121 AFMPKASKMSPMAGFKRMFGVQALVELTKGIAKFSVVAITAFLLLSTYLNDILMLSQDHL 180 A P K++P+ G KR+F +++LVE K I K +++I ++++ L +L L Sbjct: 114 AIKPDIKKINPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPT--- 170 Query: 181 PGNIYHALDIVVWIFILLCAST---FLIV-VIDVPFQIWNHAKQLKMTKQEVKDEYKDTE 236 I ++ I L F+++ + D F+ + + K+LKM+K E+K EYK+ E Sbjct: 171 -CGIECITPLLGQILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEME 229 Query: 237 GKPEVKGRIRQLQHEMSQRRMMGEVPNADVIVVNPEHYAVAVKYDATRSTAPFVVAKGVD 296 G PE+K + RQ E+ R M V + V+V NP H A+ + Y + P V K D Sbjct: 230 GSPEIKSKRRQFHQEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTD 289 Query: 297 EVAFKIREIAREHDVAIVSAPPLARAIFHTTKIDQEIPEGLFTAVAQVLAYVFQLR-QYQ 355 +R+IA E V I+ PLARA++ +D IP A A+VL ++ + + Q Sbjct: 290 AQVQTVRKIAEEEGVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQNIEKQ 349 Query: 356 KGK 358 + Sbjct: 350 HSE 352
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 90.7 bits (225), Expect = 1e-24 Identities = 34/105 (32%), Positives = 51/105 (48%), Gaps = 3/105 (2%) Query: 6 KILVVDDFSTMRRIIKNLLRDLGFNNTQEADDGSTALPMLQKGDFDFVVTDWNMPGMQGI 65 ILV DD + +R ++ L G++ + +T + GD D VVTD MP Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 66 DLLKAIRADDNLKHLPVLMVTAEAKREQIIAAAQAGVNGYVVKPF 110 DLL I+ LPVL+++A+ I A++ G Y+ KPF Sbjct: 64 DLLPRIKKAR--PDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPF 106
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 83.7 bits (207), Expect = 1e-19 Identities = 35/168 (20%), Positives = 70/168 (41%), Gaps = 11/168 (6%) Query: 14 KIILVEDSDSERCLLLNLLDSMGFTAQGFSNAQGAIKHLQNEQVDMVITDWMMPQISGIE 73 I++ +D + R +L L G+ + SNA + + D+V+TD +MP + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 74 LCKTIKSMPCSPYTILLTGNNQNAHMIEGIESGADDFIAKPFHSGVLKVRILAGLRIIEM 133 L IK ++++ N I+ E GA D++ KPF +I + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLT----------ELIGI 114 Query: 134 QQK-LASHNKTLNQMLVKEQDYLNCLRQDLSLAAQLQRALLPKNSDLT 180 + LA + +++ QD + + + ++ + +DLT Sbjct: 115 IGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLT 162
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 78.7 bits (194), Expect = 5e-17 Identities = 26/112 (23%), Positives = 55/112 (49%) Query: 878 ILLAEDSPANQIVASALLNKSGFKVEIANNGIEALKMASTKEYGLILMDMRMPEMDGIEA 937 IL+A+D A + V + L+++G+ V I +N + + + L++ D+ MP+ + + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 938 TQKILQLDPSQIVIAMTANVQKEDVELCMSAGMKDFVPKPVNRENLVNVVNQ 989 +I + P V+ M+A G D++PKP + L+ ++ + Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 489 bits (1260), Expect = e-172 Identities = 164/486 (33%), Positives = 264/486 (54%), Gaps = 18/486 (3%) Query: 5 SSFTALLVEDSMSLGALYTEYLRADGARVTHVNHGEDALNELKRWQPDLLVLDIQLPDMS 64 + T L+ +D ++ + + L G V ++ + DL+V D+ +PD + Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 65 GMDILETVQQQYPDITVIMITAHGTIDIAVDAMRSGAFDFLVKPFDAKRLSITVRNALKQ 124 D+L +++ PD+ V++++A T A+ A GA+D+L KPFD L + AL + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 125 RQLVNLVAKYESSLPKPHYMGFVGESLAMQTVYKTIDCVANSKASAFIIGESGTGKEVCA 184 + + M VG S AMQ +Y+ + + + + I GESGTGKE+ A Sbjct: 122 PKR----RPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVA 177 Query: 185 HAIHNAGNRHDGPFVALNCASIPKDLIESEIFGHTKGAFTGAIANRDGAATRAHNGTLFL 244 A+H+ G R +GPFVA+N A+IP+DLIESE+FGH KGAFTGA G +A GTLFL Sbjct: 178 RALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFL 237 Query: 245 DEICEMDLELQSKLLRFIQTGVFQRVGGTKEEKVDVRFVSATNRMPWDEVKAGRFREDLF 304 DEI +M ++ Q++LLR +Q G + VGG + DVR V+ATN+ + G FREDL+ Sbjct: 238 DEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLY 297 Query: 305 YRLHVIPIELPPLRMRGKDILLLASNLLKEYNKEEGKRFKGISCDAKQCLKSYQWPGNVR 364 YRL+V+P+ LPPLR R +DI L + +++ K EG K +A + +K++ WPGNVR Sbjct: 298 YRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEK-EGLDVKRFDQEALELMKAHPWPGNVR 356 Query: 365 QLQNVIRQIVVLNDGELVELDMLPIQMTATSETTLAKVSEPVQQDQSVSIAASNSAPVSF 424 +L+N++R++ L +++ +++ ++ + P+++ + S + S S V Sbjct: 357 ELENLVRRLTALYPQDVITREIIENELRSE------IPDSPIEKAAARSGSLSISQAVE- 409 Query: 425 LEGIESAGFSADEHFPAVTPEAKSDDIVPLWLTEKQTIENAIALCKGNVPKAAALLDISA 484 E+ A+ P D + L E I A+ +GN KAA LL ++ Sbjct: 410 ----ENMRQYFASFGDALPPSGLYDRV--LAEMEYPLILAALTATRGNQIKAADLLGLNR 463 Query: 485 STIYRK 490 +T+ +K Sbjct: 464 NTLRKK 469
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 59.4 bits (144), Expect = 6e-12 Identities = 41/190 (21%), Positives = 70/190 (36%), Gaps = 28/190 (14%) Query: 1 MRVLITGAAGQLGQALLSIAELTQVTAAELTAPQQML----------VALLPEVLACIAT 50 M+ L+TGAAG +G V+ L A Q++ V+L L +A Sbjct: 1 MKYLVTGAAGFIG---------FHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQ 51 Query: 51 TDEVIGVSHQQLDICALHSIQAAFDAFKPDVVINCAAFNGVDKAETDTDKAIAVNATGPK 110 G ++D+ + F + + V V + + N TG Sbjct: 52 P----GFQFHKIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFL 107 Query: 111 LLAGECKRLNI-RLVHISTDFVFDGALKRPYTEQDMPS-PLSAYGRSKLEGERWV---ND 165 + C+ I L++ S+ V+ K P++ D P+S Y +K E + Sbjct: 108 NILEGCRHNKIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSH 167 Query: 166 ILGAKATIIR 175 + G AT +R Sbjct: 168 LYGLPATGLR 177
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 31.7 bits (72), Expect = 0.003 Identities = 9/42 (21%), Positives = 18/42 (42%), Gaps = 1/42 (2%) Query: 211 MEEGDALATAAFERYIDRLARSLAHIINVLDP-DIIVLGGGV 251 + GD A A + R+ +++ + D+IV G+ Sbjct: 291 FKNGDKRAQLALNVFAYRVKKTIGSYAAAMGGVDVIVFTAGI 332
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 55.4 bits (133), Expect = 1e-11 Identities = 19/112 (16%), Positives = 38/112 (33%), Gaps = 6/112 (5%) Query: 29 RAALIRSANQCFTASDYDSVSIRLIAQQADVNMAMIRYYFGDKLGLFEAMV---TEQIQP 85 R ++ A + F+ S S+ IA+ A V I ++F DK LF + I Sbjct: 13 RQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGE 72 Query: 86 IYQRAKALQKSHDKPTIADLITEFYQTMIPNPEFPRF---LFRLMNSDGSSE 134 + +A + +++ ++ + +F G Sbjct: 73 LELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMA 124
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 51.0 bits (122), Expect = 5e-09 Identities = 58/289 (20%), Positives = 100/289 (34%), Gaps = 60/289 (20%) Query: 110 RLAQAQADRKALEGQLEGKKLQLKNLQLSLEIENNRYDLVKSDLKRKETLRKQNLISQSE 169 + + Q + E L+ K+ + + + N + KS L +L + I+ Sbjct: 194 QFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIA--- 250 Query: 170 LDGERQNLLAQQQKLQELDNSLN-----LMPNETQILEA-----------------QRLQ 207 + +L Q+ K E N L L E++IL A + Q Sbjct: 251 ----KHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQ 306 Query: 208 AVAREQEAQSQLTK-------TEIRLPFEGRVAEVNVES-SQVVSPQQVLARINGI-EVM 258 +L K + IR P +V ++ V + VV+ + L I + + Sbjct: 307 TTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTL 366 Query: 259 EVEAQVSLGDVMTLMKTVNRPQEQEKQLPRAETLGLSAEITLKGATYSF--SWPAQITRI 316 EV A V Q K + G +A I ++ Y+ ++ I Sbjct: 367 EVTALV-----------------QNKDIGFINV-GQNAIIKVEAFPYTRYGYLVGKVKNI 408 Query: 317 G--ETVDPTLATVSVVLQVEQQYRDLKMGQSPPLVNGMFVSARIKGGER 363 D L V V+ ++ ++ PL +GM V+A IK G R Sbjct: 409 NLDAIEDQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGMR 457
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 452 bits (1164), Expect = e-144 Identities = 217/1050 (20%), Positives = 441/1050 (42%), Gaps = 53/1050 (5%) Query: 1 MIGFFVRHPTATTLLMLAFIVLGIKALPELKRETFPEFSKNYITAQVVLPGASPQDVEEN 60 M FF+R P +L + ++ G A+ +L +P + ++ PGA Q V++ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 LCLRMEDAVDSLGSIIETKCDAL-EGVARMTLKLDDKADLSRSLVDVQTKISAIKD-FPA 118 + +E ++ + +++ + G +TL D + V VQ K+ P Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 119 EIEPPIVEELDFNERII----DIAVSAATSKPELKAYAED-LKRRLKLDTSISQVEISGF 173 E++ + + + ++ + T++ ++ Y +K L + V++ G Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG- 179 Query: 174 SSHQLLVEISLGAIKRLGMSVADVAKQIEQQNVQLPSGTVETPSK------NILIRFDQR 227 + + + + + + + ++ DV Q++ QN Q+ +G + N I R Sbjct: 180 AQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 228 EVEPERLANIVIRSDALGGVVRLRDIATITDRFELDEESIRFDGEQAAILTVYKNKSQDS 287 PE + +R ++ G VVRL+D+A + E R +G+ AA L + ++ Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 288 LRLKEEVIGFLDAEKLRTPNGISISTSNDLSSLLWDRLTMLVKNGWQGVVLVFLCMWLF- 346 L + + L + P G+ + D + + + +VK ++ ++LVFL M+LF Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 347 FSLRYSFWVAMGLPIAFMGSLFFMAQVGLTINIMTLVAFLMAIGIMMDDAIVIAESIA-A 405 ++R + + +P+ +G+ +A G +IN +T+ ++AIG+++DDAIV+ E++ Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 406 HIERGMSKADAVIQGVKRVLPGVVSSFLTTVFIFSSIAFMEGDMGKVLRVVPQTLLLILT 465 +E + +A + + ++ +V + +F +AF G G + R T++ + Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 466 ISLVEAFLILPNHLAHSAKGKQRKTSRFKQKFNHKFE---HFRTVQLVAAVEWVINWRYV 522 +S++ A ++ P A K + K F F +V ++ Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 523 FMGSVISLLFISISLVAGGAIKFVGFPELDGDVAEARIILPPGSTLQQTEHVVNRVVSVA 582 ++ +I L ++ +V + PE D V I LP G+T ++T+ V+++V Sbjct: 540 YL--LIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYY 597 Query: 583 KALGDKYSEKEDGHRLIQHITERFNFNADAGENGAHVATVKVDLLSAEVRQTLMSTFI-R 641 K + ++ + F+ A +A V + + + Sbjct: 598 L----KNEKAN-----VESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIH 648 Query: 642 EWQQGVGEMVDPIAIVFKQPK---MGPAGRA--IEIRVRGDDLDELKSAAIDV-QQYLQG 695 + +G++ D I F P +G A I G D L A + Q Sbjct: 649 RAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQH 708 Query: 696 FNGVSGVMDSMRPGKAEILMTLKPG-AEAFGVN----GMMLASQLRGAYFHQTADNIQVG 750 + V + A+ + + A+A GV+ +++ L G Y + Sbjct: 709 PASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVND----FIDR 764 Query: 751 PESIQIDVQLDKTDAAKLENLANFPITIGTDGEQVPLSAVADFEWQRGYVKISRLDGMRF 810 ++ VQ D E++ + +GE VP SA W G ++ R +G+ Sbjct: 765 GRVKKLYVQADAKFRMLPEDVDKLYVRSA-NGEMVPFSAFTTSHWVYGSPRLERYNGLPS 823 Query: 811 VTITGEVDTHLANASEINDAFKAELLPELKKRYPGIRVSYEGEVKESKTTQNSMASGFIV 870 + I GE A + DA A + K GI + G + + + N + + Sbjct: 824 MEIQGEA----APGTSSGDA-MALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAI 878 Query: 871 GLLAVFAILSLQFKSYIEPLVVMAVIPLGLIGVLWGHLLLGYSMSMPSIMGFVALAGVVV 930 + VF L+ ++S+ P+ VM V+PLG++GVL L + ++G + G+ Sbjct: 879 SFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSA 938 Query: 931 NDSILLVQYIR-YHVEEGQSVHEAVVSASKERFRAVFITSLTTAAGMLPLLLETSIQAQV 989 ++IL+V++ + +EG+ V EA + A + R R + +TSL G+LPL + + Sbjct: 939 KNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGA 998 Query: 990 LQPLVVSMVFGIFASTALVLFMVPACYAIL 1019 + + ++ G+ ++T L +F VP + ++ Sbjct: 999 QNAVGIGVMGGMVSATLLAIFFVPVFFVVI 1028
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 28.6 bits (63), Expect = 0.027 Identities = 13/40 (32%), Positives = 25/40 (62%) Query: 221 LVVIRTISDKADGSAHLVYEEAKQVTADNSVAITLNMIRE 260 L +I+++SD +D S L ++ K+ N+ +I +N I+E Sbjct: 193 LNLIKSLSDDSDSSDLLFSQKFKEKLELNNKSIDINFIKE 232
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 52.9 bits (127), Expect = 6e-09 Identities = 27/115 (23%), Positives = 44/115 (38%), Gaps = 5/115 (4%) Query: 1022 KVLCIDNEEAILAGLESLLSRWQCEVICAKDLADARIKLGLKGVAPDIVLADYHLDDGQN 1081 +L D++ AI L LSR +V + A + D+V+ D + D N Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRW--IAAGDGDLVVTDVVMPDE-N 61 Query: 1082 GVDAMDGIRGLYGEHLPGILITANTRKDL-IDDMHKRGYHYMAKMVKPAALRALI 1135 D + I+ LP ++++A I K Y Y+ K L +I Sbjct: 62 AFDLLPRIKKAR-PDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGII 115
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 71.0 bits (174), Expect = 1e-16 Identities = 30/119 (25%), Positives = 53/119 (44%), Gaps = 6/119 (5%) Query: 8 IIIADDHPLFRNALRQALSSEFKNTQWFEADSADALQALLES-SDIEYDVVLLDLQMPGS 66 I++ADD R L QALS ++ L + + D+V+ D+ MP Sbjct: 6 ILVADDDAAIRTVLNQALSRAG-----YDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 67 HGYSTLIHLRTHFQELPVVVISAHEDNLTISRAIHYGSSGFIPKSSSMETLAEALEAVL 125 + + L ++ +LPV+V+SA +T +A G+ ++PK + L + L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 27.2 bits (60), Expect = 0.028 Identities = 12/44 (27%), Positives = 24/44 (54%), Gaps = 1/44 (2%) Query: 66 VTVSSDRIDFNKPIPAGSLAEIIARVIHVGNTSIKVEVNIFVED 109 V V+ + K I G++ + RV+ G+ S ++ +N+ +ED Sbjct: 383 VKVTGKEVAELKGITYGTMLRMTPRVLTQGDKS-EISLNLHIED 425
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 299 bits (766), Expect = 6e-94 Identities = 106/418 (25%), Positives = 180/418 (43%), Gaps = 65/418 (15%) Query: 384 QPGDVLVTDMTDPDWEPIMK-RASAIVTNRGGRTCHAAIIARELGVPAVVGCGDVTERIK 442 + ++ D+T D + K T+ GGRT H+AI++R L +PAVVG +VTE+I+ Sbjct: 155 EETVIIAEDLTPSDTAQLNKQFVKGFATDIGGRTSHSAIMSRSLEIPAVVGTKEVTEKIQ 214 Query: 443 NGQEITVSCAEG---------DTGLIYNGLQDFEVISSRVDSMPELP--------MKITM 485 +G + V EG + FE + P +++ Sbjct: 215 HGDMVIVDGIEGIVIVNPTEEEVKAYEEKRAAFEKQKQEWAKLVGEPSTTKDGAHVELAA 274 Query: 486 NVGNPDRAFDFARLPNEGVGLARLEFIINRMIGIHPKALLEFNDQTAELQQEIHEMIAGY 545 N+G P EG+GL R EF+ + ++E Sbjct: 275 NIGTPKDVDGVLANGGEGIGLYRTEFLY-------------MDRDQLPTEEE-------- 313 Query: 546 ESPVEFYVARLVEGIATIASAFHPKKVIVRMSDFKSNEYANLVGGDRYEPEEENPMLGFR 605 E + K V++R D ++ + + P+E NP LGFR Sbjct: 314 ----------QFEAYKEVVQRMDGKPVVIRTLDIGGDKELSYL----QLPKELNPFLGFR 359 Query: 606 GASRYISESFRDCFALECEAIKRVRNEMGLKNVEIMIPFVRTLSEAAQVIELLKEQGLER 665 + + +D F + A+ R N+++M P + TL E Q +++E+ + Sbjct: 360 AIRLCLEK--QDIFRTQLRALLRAS---TYGNLKVMFPMIATLEELRQAKAIMQEEKDKL 414 Query: 666 GKDG------LRVIMMCELPSNALLAEQFLEHFDGFSIGSNDLTQLTLGLDRDSGIISHL 719 +G + V +M E+PS A+ A F + D FSIG+NDL Q T+ DR + +S+L Sbjct: 415 LSEGVDVSDSIEVGIMVEIPSTAVAANLFAKEVDFFSIGTNDLIQYTMAADRMNERVSYL 474 Query: 720 FDERNDAVKALLSMAIKAAKAKGAYVGICGQGPSDHPDFAAWLVEQGIDTVSLNPDTV 777 + + A+ L+ M IKAA ++G +VG+CG+ D L+ G+D S++ ++ Sbjct: 475 YQPYHPAILRLVDMVIKAAHSEGKWVGMCGEMAGD-EVAIPLLLGLGLDEFSMSATSI 531
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 54.0 bits (130), Expect = 4e-10 Identities = 38/155 (24%), Positives = 66/155 (42%), Gaps = 20/155 (12%) Query: 109 VRSPKSFLGATGLRDSQIALFEDIVTLMMMHIKAQAEKNLGTKVITHAVIGRPVNFQGIG 168 R+P + ++D IA F + M+ H Q N + ++ PV + Sbjct: 64 GRTPGNIAAIRPMKDGVIADFF-VTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQV- 121 Query: 169 GEQSNQQAEAILSLAAKRAGFTDVDFLFEPLAAGMDYEASLEENMTVLVVDVGGGTTDCS 228 + AI +A+ AG +V + EP+AA + + E +VVD+GGGTT+ + Sbjct: 122 ------ERRAIRE-SAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVA 174 Query: 229 MVKMGPNHIDNRDRSADFLGHSGQRIGGNDLDIAL 263 ++ + + S RIGG+ D A+ Sbjct: 175 VISLN-----------GVVYSSSVRIGGDRFDEAI 198
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 44.1 bits (104), Expect = 4e-08 Identities = 16/56 (28%), Positives = 32/56 (57%) Query: 1 MHRPTASRGFTLIELVIVIIVLGILAVIATAKYVDLKRDAEVARVKATAAALQQSV 56 M RGFTL+E+++VI+++G+LA + + K A+ + + AL+ ++ Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENAL 56
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 66.0 bits (161), Expect = 1e-14 Identities = 30/130 (23%), Positives = 54/130 (41%), Gaps = 4/130 (3%) Query: 3 RIAIVEDEAAIRENYKEVLQQQGYCVQAYANRPQAMLAFNTRLPDLAIIDIGLENEIDGG 62 I + +D+AAIR + L + GY V+ +N DL + D+ + +E Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE--NA 62 Query: 63 FTLCQSLRAMSSTLPIIFLTARDSDFDTVCGLRLGADDYLSKDVSFPHLIA--RLAALFR 120 F L ++ LP++ ++A+++ + GA DYL K LI A Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 121 RSDLKNVSND 130 + + +D Sbjct: 123 KRRPSKLEDD 132
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 76.1 bits (187), Expect = 3e-18 Identities = 28/95 (29%), Positives = 49/95 (51%), Gaps = 2/95 (2%) Query: 126 ELALGLNVQFKTGSSTIEPHFQNQLNDIAYAMS--LSPELTLDLTGYADRRGDGDYNQAL 183 L +V F +T++P Q L+ + +S + ++ + GY DR G YNQ L Sbjct: 214 HFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGL 273 Query: 184 SEQRVAEVKNYLIEQGVAEARLHNQAYGDSSPLMA 218 SE+R V +YLI +G+ ++ + G+S+P+ Sbjct: 274 SERRAQSVVDYLISKGIPADKISARGMGESNPVTG 308
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 57.3 bits (138), Expect = 2e-12 Identities = 20/107 (18%), Positives = 43/107 (40%), Gaps = 1/107 (0%) Query: 3 RSEQKRLAIINAAKEEFIHHGFIAANMDRICTTAEVSKRTLYRHYESKEKLFESVLTIIQ 62 +++ R I++ A F G + ++ I A V++ +Y H++ K LF + + + Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSE 67 Query: 63 ASIDETL-TYPFNPELSLYEQLKAITYLEVDTLYNICGMALARTILL 108 ++I E Y L+ I +++ L I+ Sbjct: 68 SNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIF 114
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 52.5 bits (126), Expect = 1e-09 Identities = 20/108 (18%), Positives = 35/108 (32%), Gaps = 1/108 (0%) Query: 64 VVRAAERAELAFQVGGRLINILVKEGDEVKQGQVLARLDARDATTALESAQLELKNTALD 123 + + E+ + I+VKEG+ V++G VL +L A A Q L L+ Sbjct: 90 LTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLE 149 Query: 124 HNRALVVYEKSQAISKSELD-TITTRLELARNHVEDATLQLEYTELKA 170 R ++ + EL + L + Sbjct: 150 QTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFST 197 Score = 34.8 bits (80), Expect = 5e-04 Identities = 30/196 (15%), Positives = 64/196 (32%), Gaps = 15/196 (7%) Query: 93 KQGQVLARLDARDATTALESAQLELKNTALDHNRALVVYEKSQAISKSELDTITTRLELA 152 +Q + Q+E + + LV I +L T + L Sbjct: 256 EQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEIL-DKLRQTTDNIGLL 314 Query: 153 RNHVEDATLQLEYTELKAPFAGIIGRKLVDNHIQ-IQANTPVF-ILHDLSDLEVVINIPH 210 + + + + ++AP + + + V + + I+ + LEV + + Sbjct: 315 TLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQN 374 Query: 211 KVMLSSAIASKANAELSAIPGTLFP-LALRTFGTQADAVS-----QTYPVVLGFD----- 259 K + + A ++ A P T + L + DA+ + V++ + Sbjct: 375 KDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCLS 434 Query: 260 -DLKGFRVLPGMAVKV 274 K + GMAV Sbjct: 435 TGNKNIPLSSGMAVTA 450
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 467 bits (1203), Expect = e-150 Identities = 239/1049 (22%), Positives = 452/1049 (43%), Gaps = 60/1049 (5%) Query: 3 IARYTIAKRTSVWVLIALILLGGYISYLKLGRFEDPEFVIRQAVINTAYSGATAQEVSDE 62 +A + I + WVL ++++ G ++ L+L + P ++ Y GA AQ V D Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 63 ITDVIEGAVQTLQELKEVKSVSKQGMSEVTVEIKLEFAGSSEELQQVWDKLRRKIADVQR 122 +T VIE + + L + S S S VT+ + + + Q +++ K+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGS-VTITLTFQSGTDPDIAQV---QVQNKLQLATP 116 Query: 123 QLPPGA-GPSIVNDDFSDVYALFFAV--TGEGFTDKQLQDYVD-TLRRDLVLVDGVAKTA 178 LP I + S Y + G T + DYV ++ L ++GV Sbjct: 117 LLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGD-V 175 Query: 179 TLAEQQETIFVEISSERLAKFGVSAEKVYQVLQKQNMVTVAGSIETD------AMRIAVI 232 L Q + + + ++ L K+ ++ V L+ QN AG + + ++I Sbjct: 176 QLFGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASII 235 Query: 233 PSSGIDSFTDLNNLQIGIGDNNTVLRLGDIANVTRGYKDPASMLIRYNGERAIGFGLSNV 292 + + + + + + + +V+RL D+A V G ++ + R NG+ A G G+ Sbjct: 236 AQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIA-RINGKPAAGLGIKLA 294 Query: 293 TGGNVVDMGDAVKARIAELDSQRPLGMDLNVISMQSDSVRDSVTNFIDNLIAAVVIVFLV 352 TG N +D A+KA++AEL P GM + + V+ S+ + L A+++VFLV Sbjct: 295 TGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLV 354 Query: 353 LLLFMG-VRSGVIIGFVLLLTVAGTLCIMLIDNIAMQRISLGALIIALGMLVDNAIVVTD 411 + LF+ +R+ +I + + + GT I+ ++ +++ +++A+G+LVD+AIVV + Sbjct: 355 MYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVE 414 Query: 412 GILVRMQQNPDEDRETIVSEVVDATKWPLLGGTVVGICAFSAIGLSPSDMGEYAGSLFWV 471 + M ++ +E + L+G +V F + G Sbjct: 415 NVERVMMEDKLPPKEATEKSMSQIQG-ALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSIT 473 Query: 472 ILYSMLLSWVFAVTITPMLCFDFLKVKALKVGQKPG-----------RIVTAYSTILRWV 520 I+ +M LS + A+ +TP LC LK + + + G V Y+ + + Sbjct: 474 IVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKI 533 Query: 521 IGHRALSSLMLLGTLATAIWGVQFVPPGFMPESQRAQFVVDVYLPQGSDIKRTEALVANI 580 +G L+ +A + +P F+PE + F+ + LP G+ +RT+ ++ + Sbjct: 534 LGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQV 593 Query: 581 EQDVKAKEGITNITSFIGGGGLRFMLTYAPEPRNPSYGQL-LIDIDDYKKIAP----LLG 635 E N+ S G F + + +N + L ++ ++ Sbjct: 594 TDYYLKNE-KANVESVFTVNGFSF----SGQAQNAGMAFVSLKPWEERNGDENSAEAVIH 648 Query: 636 ELQSELDAKYPDASVKVWKFM----LGRGGGKKIE-AGFKGPDSQVLRQLAEE-AKVILL 689 + EL K D V + LG G E G L Q + + Sbjct: 649 RAKMEL-GKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQ 707 Query: 690 NDSNLIAVQDDWRQQVPVLRPVYSAEEAQRYGLTTQEINQAIAQTLTGRNVGVYREGDDL 749 + ++L++V+ + + + E+AQ G++ +INQ I+ L G V + + + Sbjct: 708 HPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRV 767 Query: 750 IPIVVRSPQNERNHQRAIENTEVFSHTQGGFIPVSQLVDSVDVVYQDDMLRRIDRMPTIL 809 + V++ R ++ V S G +P S VY L R + +P++ Sbjct: 768 KKLYVQADAKFRMLPEDVDKLYVRSAN-GEMVPFSAFTT-SHWVYGSPRLERYNGLPSME 825 Query: 810 VQADPAPGVLTADAFNKVRSKIEAI--ELPAGYELIWYGEYKASKDANEGLVISAPYGFA 867 +Q + APG + DA + +E + +LPAG W G + + F Sbjct: 826 IQGEAAPGTSSGDA----MALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFV 881 Query: 868 AMILSVIFMFNAIRQPLVIWLTAPLAIIGVSVGLIIFQTPFEFMAILGFLSLIGMMVKNA 927 + L + ++ + P+ + L PL I+GV + +F + ++G L+ IG+ KNA Sbjct: 882 VVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNA 941 Query: 928 IVLVDQA-DVEVREGKSGYDAIINAALSRARPVLLGALTTILGVAPLLIDP-----FFKS 981 I++V+ A D+ +EGK +A + A R RP+L+ +L ILGV PL I + Sbjct: 942 ILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNA 1001 Query: 982 MAVTIMFGLMFATILTLVVIPLFYSIFFR 1010 + + +M G++ AT+L + +P+F+ + R Sbjct: 1002 VGIGVMGGMVSATLLAIFFVPVFFVVIRR 1030
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 122 bits (308), Expect = 4e-36 Identities = 80/260 (30%), Positives = 125/260 (48%), Gaps = 21/260 (8%) Query: 5 LAGKVALITGAARGVGLATAKLMAKEGAQVIFTDINAEQGQEIANSISSNALFLEH---D 61 + GK+A ITGAA+G+G A A+ +A +GA + D N E+ +++ +S+ + A E D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 62 VTKEADWSSILTHIKSKYGQLNILVNNAAILQLGDIKEETLAGWQKVHRVNSDSVFLGIH 121 V A I I+ + G ++ILVN A +L+ G I + W+ VNS VF Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 122 YALPLMEESGGGSIVNMSSSSAIFGMPHFAAYGASKAAIRGLSQSVAVYCSQTKNNVRCN 181 M + GSIV + S+ A AAY +SKAA ++ + + ++ N+RCN Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEY--NIRCN 183 Query: 182 TLHPDSIMTPMVMEMSAQAGDRSLAEPERAKAYLCQ------------PEDVANTILFLA 229 + P S T M + A + K L P D+A+ +LFL Sbjct: 184 IVSPGSTETDMQWSLWADEN----GAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLV 239 Query: 230 SDESKHINGAAIALDGGATV 249 S ++ HI + +DGGAT+ Sbjct: 240 SGQAGHITMHNLCVDGGATL 259
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 424 bits (1092), Expect = e-134 Identities = 202/1054 (19%), Positives = 417/1054 (39%), Gaps = 62/1054 (5%) Query: 12 FARNSVAANLLMIIIIIGGLLTANTIRKQFFPAVEINWLEFNAVYPGAAPQEVEEGITIK 71 F R + A +L II+++ G L + +P + + +A YPGA Q V++ +T Sbjct: 5 FIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQV 64 Query: 72 IEEALESVQGLKRVITYSNRNVSSG-YFRVEDSYDPQVVLEEVKSEIDSI-SSFPDGMER 129 IE+ + + L + + S+ S + DP + +V++++ P +++ Sbjct: 65 IEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQQ 124 Query: 130 PKVERIKLRQE-VMYMSLY---GDLSQRQLKDLGEK-IHDELLQLPLVNITDFYGGLGYE 184 + K +M +Q + D + D L +L V +G Y Sbjct: 125 QGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA-QYA 183 Query: 185 IAIEVSKDRLREFGLSFNDVAEAVRGYSRNMSAGQIRAE------NGYINLRVQNQAYVG 238 + I + D L ++ L+ DV ++ + ++AGQ+ ++ Q + Sbjct: 184 MRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKNP 243 Query: 239 YEFESLPLITLEDGTTLLLGDVATVIDGFEEGIQYSKFNGKNSVTFFIGAANDQSLTDVA 298 EF + L DG+ + L DVA V G E ++ NGK + I A + D A Sbjct: 244 EEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDTA 303 Query: 299 DVVKGYILDKQKVLPQGVKLEPWVDMTYYLEGRLNLMLDSMKSGAILVFILLALFLR-VR 357 +K + + Q PQG+K+ D T +++ ++ ++ ++ +LVF+++ LFL+ +R Sbjct: 304 KAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMR 363 Query: 358 LAFWVMMGLPVCFLGTLLFMPMGMIDVTINVISLFAFILVLGIVVDDAIVMGESAH-AEC 416 + +PV LGT + +IN +++F +L +G++VDDAIV+ E+ Sbjct: 364 ATLIPTIAVPVVLLGTFAILAA--FGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 417 EEKGQTLDNVIRGVKRVAMPATFGVLTTIAAFLPITLDDGPSSAFGQAIGFVVILCLIFS 476 E+K + + + ++ + A F+P+ G + A + ++ + S Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 477 LVESKLILPAHLARMKPKTIVKPGSKNPVDWLRNIVNFLQAKVDTGLKIFITQYYRPFLE 536 ++ + ++ PA A + +KP S + + D +Y + Sbjct: 482 VLVALILTPALCATL-----LKPVSAEHHENKGGFFGWFNTTFD-----HSVNHYTNSVG 531 Query: 537 VAVKYRYTVIMVFFSLILICAGLYSGGLIRFIGQPKIPHDF-PRI---SFEMNIDASEKA 592 + ++++ ++ L+ ++P F P F I A Sbjct: 532 KILGSTGRYLLIYALIVAGMVVLF----------LRLPSSFLPEEDQGVFLTMIQLPAGA 581 Query: 593 TLSAALSIEEALRLVDSKLEEEYGQKMISDMQVELRGRTS----AQVMTKLVDPEIRPID 648 T + + + K E+ + + + G+ A V K + + Sbjct: 582 TQERTQKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDEN 641 Query: 649 TFAVAELWRQNMPL--IPGMKSFTIQDNLFGGGRDDGDISFRLE---GKDDAQLVAAAKE 703 + A A + R M L I F L G L A + Sbjct: 642 S-AEAVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQ 700 Query: 704 LKAKLNTLKG-VGDVNDSRQSSAKEIQFELK-PLAHSLGLTLADIARQVGNSFYGLEAQR 761 L + V + + + E+ A +LG++L+DI + + + G Sbjct: 701 LLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVND 760 Query: 762 ILRNGEEIKVMLRYPEEQRNSIAQVSDVIIKTPQGAEIPLSEVAAIVVTDGVNSIRRENG 821 + G K+ ++ + R V + +++ G +P S G + R NG Sbjct: 761 FIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNG 820 Query: 822 NRTINVWGSVDADQAEPFKLAKDIRDNFLPELLNKYPR-VKSEVSGNIQEQLDSADTQLR 880 ++ + G + +A + L +K P + + +G ++ S + Sbjct: 821 LPSMEIQGEAAPGTSSGDAMAL------MENLASKLPAGIGYDWTGMSYQERLSGNQAPA 874 Query: 881 DFLISMLVIYSLLAVPLKSYSQPIMIMAVIPFGVIGSVLGHMILGLDLSALSVFGIIAAA 940 IS +V++ LA +S+S P+ +M V+P G++G +L + + G++ Sbjct: 875 LVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTI 934 Query: 941 GVVVNDSLVMVDYINKSRE-SGIAMKLSVLEAGCRRFRAILLTSLTTFIGLVPIMTETSM 999 G+ +++++V++ E G + + L A R R IL+TSL +G++P+ Sbjct: 935 GLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGA 994 Query: 1000 QAQMVIPMAVSLAFGVLFATVVTLVLIPCLYVTI 1033 + + + + G++ AT++ + +P +V I Sbjct: 995 GSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVI 1028
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 42.9 bits (101), Expect = 2e-06 Identities = 31/154 (20%), Positives = 56/154 (36%), Gaps = 26/154 (16%) Query: 52 PMSFAVTSYGVVNAKYETELVSQLNGEIVFLSDKFVR-GGFVKKGDVLAKIDPSDYEAAL 110 + T+ G + ++ + + IV + V+ G V+KGDVL K+ EA Sbjct: 79 QVEIVATANGKLTHSGRSKEIKPIENSIV--KEIIVKEGESVRKGDVLLKLTALGAEADT 136 Query: 111 IDAKANMASARA--------------------TLVQEKAFGKVAEAEWKRIENGVPTELS 150 + ++++ AR L E F V+E E R+ + + + S Sbjct: 137 LKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFS 196 Query: 151 LRKPQLAQEVAKLNSSEA---GLKRAIRNLERTI 181 + Q Q+ L+ A + I E Sbjct: 197 TWQNQKYQKELNLDKKRAERLTVLARINRYENLS 230 Score = 38.3 bits (89), Expect = 5e-05 Identities = 33/210 (15%), Positives = 71/210 (33%), Gaps = 28/210 (13%) Query: 105 DYEAALIDAKANMASARATLVQEKAFGKVAEAEWKRIENGVPTELSLRKPQLAQEVAKLN 164 + E ++A + ++ L Q ++ A+ E++ + E+ +L Q + Sbjct: 256 EQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEIL---DKLRQTTDNIG 312 Query: 165 SSEAGLKRAIRNLERTIIKAPFDALIEARNI-GLGSYVSMGTPLGKVLSTAH---AEVRL 220 L + + ++I+AP ++ + G V+ L ++ + Sbjct: 313 LLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALV 372 Query: 221 PIADKELQFLDNKGKGAEVML---------TGELAGQTKQWPARIVRSEGVIDSRSRMTY 271 D + G ++ G L G+ K + + + D R + + Sbjct: 373 QNKD-----IGFINVGQNAIIKVEAFPYTRYGYLVGKVKN-----INLDAIEDQRLGLVF 422 Query: 272 LVAEVTDPYGLNANNN--ELRYGTYVTASI 299 V + L+ N L G VTA I Sbjct: 423 NVIISIEENCLSTGNKNIPLSSGMAVTAEI 452
>SECA#SecA protein signature. Length = 901 Score = 50.6 bits (121), Expect = 1e-10 Identities = 18/75 (24%), Positives = 31/75 (41%), Gaps = 5/75 (6%) Query: 37 LTLLVQNAEREAEILQLLSDNELVGLITVDETQEENVVQLMGLLNKPQTTRFEKTPNRND 96 + + + E E + + L + + +++ E+ RND Sbjct: 829 VQVRMPEEVEELEQQRRMEAERLAQMQQLSHQDDDSAAA-----AALAAQTGERKVGRND 883 Query: 97 PCVCGSGQKYKKCCG 111 PC CGSG+KYK+C G Sbjct: 884 PCPCGSGKKYKQCHG 898
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 90.7 bits (225), Expect = 1e-21 Identities = 76/395 (19%), Positives = 157/395 (39%), Gaps = 16/395 (4%) Query: 38 LDMTIANVALPHMMGALGVTSDQVTWVLTSYSMAEAIFIPLASFLALKFGVRNLLLISVS 97 L+ + NV+LP + WV T++ + +I + L+ + G++ LLL + Sbjct: 28 LNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGII 87 Query: 98 GFMISSALCGQADSIAEMVTF-RVMQGAFGASVIPLSQSIMVQIYPANQRGKAMALFSVG 156 S + S ++ R +QGA A+ L ++ + P RGKA L Sbjct: 88 INCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSI 147 Query: 157 VLLGPILGPTLGGIITENMNWRWIFYVNLPIGAICLTLIYTFVKLGGKGKPKIDWPIVIA 216 V +G +GP +GG+I ++W ++ + + L+ +K + K D +I Sbjct: 148 VAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMK-LLKKEVRIKGHFDIKGIIL 206 Query: 217 MTIGIGLLQMVLDRGNQESWFESNTILFSAIISAIAIIFFVARSFITKSEIAPVWLLHDR 276 M++GI + S +I F I+S ++ + FV L + Sbjct: 207 MSVGIVFFMLFTT---------SYSISF-LIVSVLSFLIFVKHIRKVTDPFVDPGLGKNI 256 Query: 277 NLAMSCLVMAGFSMG-MFGITQLQPMMLEQLLNY-PVETTGFAMAPRGLASAIVLLAMAR 334 M ++ G G + G + P M++ + E + P ++ I Sbjct: 257 PF-MIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGI 315 Query: 335 YMDKIDARLLIAVGLSLNALGTYLMTQYSLEIDIYWILLPSIIQGAGMGLVFAPLSQLAY 394 +D+ ++ +G++ ++ +L + LE +++ + + G+ +S + Sbjct: 316 LVDRRGPLYVLNIGVTFLSVS-FLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVS 374 Query: 395 TTLSPKDTIGGAVVFNLCRTIGGSFGISIVNTYFS 429 ++L ++ G + N + GI+IV S Sbjct: 375 SSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 71.4 bits (175), Expect = 8e-16 Identities = 37/274 (13%), Positives = 81/274 (29%), Gaps = 34/274 (12%) Query: 88 FQAKLDEARAAYEMALQNNAATDDAILAASANVKSAVAQLSDAQVTYKRTKDLVDKELLP 147 + + + N L A + + L+ K+ + Sbjct: 191 IKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIA 250 Query: 148 EQQLDDTRAKLSAAEQSVIAARATMAQLIKS-------------------QGAHGNAAPE 188 + + + K A + ++ + Q+ Sbjct: 251 KHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDN 310 Query: 189 VKKAAAALSQASLSLSYTNIFAPKDGHLGKLSAHA-GSVVSPGQAIVPLV-VDNTYWVQA 246 + L++ + I AP + +L H G VV+ + ++ +V D+T V A Sbjct: 311 IGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTA 370 Query: 247 NFKETQLERLTAGQTATITLDLYPKVDYH---GTIEAISPASGASFTLLPPENATGNWVK 303 + + + GQ A I ++ +P Y G ++ I+ + + G Sbjct: 371 LVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDA-------IEDQRLGLVFN 423 Query: 304 VPQRFPVLVRLTNESEHPDFPLRVGASANVSIDT 337 V + + + + PL G + I T Sbjct: 424 VIIS---IEENCLSTGNKNIPLSSGMAVTAEIKT 454 Score = 43.3 bits (102), Expect = 8e-07 Identities = 15/116 (12%), Positives = 43/116 (37%) Query: 55 IAPQVSGKVSSVNASDYQKVSQGDLLVQIDSAPFQAKLDEARAAYEMALQNNAATDDAIL 114 I P + V + + + V +GD+L+++ + +A + +++ A Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSR 158 Query: 115 AASANVKSAVAQLSDAQVTYKRTKDLVDKELLPEQQLDDTRAKLSAAEQSVIAARA 170 + N + + ++++ L ++Q + + E ++ RA Sbjct: 159 SIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRA 214
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 42.5 bits (100), Expect = 2e-06 Identities = 24/112 (21%), Positives = 50/112 (44%), Gaps = 4/112 (3%) Query: 102 VNRLSANVESQQSALEKAQRDVERLKPLYEQDAASQLDFDNALSVLSQAKSSVAASKAEL 161 + +S LE+ + ++ K Y+ +QL + L L Q ++ EL Sbjct: 261 YVEAVNELRVYKSQLEQIESEILSAKEEYQL--VTQLFKNEILDKLRQTTDNIGLLTLEL 318 Query: 162 EEAKLELSYTEIKSPISGLVSRSEV-DIGALVGSSGQSLLTRVKQVDPIYVT 212 + + + I++P+S V + +V G +V + ++L+ V + D + VT Sbjct: 319 AKNEERQQASVIRAPVSVKVQQLKVHTEGGVVT-TAETLMVIVPEDDTLEVT 369
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 941 bits (2435), Expect = 0.0 Identities = 421/1028 (40%), Positives = 631/1028 (61%), Gaps = 9/1028 (0%) Query: 1 MAQYFVNRPVFASVISIVIVLLGLIAMFQLPIDQYPYITPPQVKISASYPGATSTTAAES 60 MA +F+ RP+FA V++I++++ G +A+ QLP+ QYP I PP V +SA+YPGA + T ++ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VATPLEQELNGLPNMIYMSSKSTNSGSSNITITFDVGTNPDLAAVDAQNSTQQATGSLPI 120 V +EQ +NG+ N++YMSS S ++GS IT+TF GT+PD+A V QN Q AT LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 DVQTEGVSVSKEASVELLKLALTSEDERYDEIYLSNYATINIQSALKRIPGVGRVRNTGA 180 +VQ +G+SV K +S L+ S++ + +S+Y N++ L R+ GVG V+ GA Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 RSYSMRVWLNPDTMAGYGLTTSDVIDAIKAQNKESPAGSIGSQPNADTLSMTLPITAAGR 240 + Y+MR+WL+ D + Y LT DVI+ +K QN + AG +G P + I A R Sbjct: 181 Q-YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 241 MSSVPQFNEIIVRASADGSIIRLRDIANIELGSSSYTLQSQLNGNNATILQVYLLPGANA 300 + +F ++ +R ++DGS++RL+D+A +ELG +Y + +++NG A L + L GANA Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 301 LEVTKKVKAEMAKLAQKFPQGMNWEVFFDASVFIENSIDEVVKTLVEALILVILVVFMFL 360 L+ K +KA++A+L FPQGM +D + F++ SI EVVKTL EA++LV LV+++FL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 361 QNIRATLIPAIAVPVSLIGTLAAMLAFGFTINTVSLLALVLAIGIVVDDAIVVVENVERL 420 QN+RATLIP IAVPV L+GT A + AFG++INT+++ +VLAIG++VDDAIVVVENVER+ Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 421 MDEKGLSSSQATKVAMKELSGALIATSLVLAAVFVPVSFLSGITGIMYREFAVAITVAVL 480 M E L +AT+ +M ++ GAL+ ++VL+AVF+P++F G TG +YR+F++ I A+ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 481 ISTVVALTLSPALCALLLKPG----DKATSGFFKWMNDRLDTATTKYVRLVVLTNKHAKR 536 +S +VAL L+PALCA LLKP + GFF W N D + Y V R Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 537 SYLLFALMVGGVYLTMSSLPSSFMPDEDQGRFFIDVSLPNGATVNRTQDVLKKAEATVLA 596 L++AL+V G+ + LPSSF+P+EDQG F + LP GAT RTQ VL + L Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 597 HP-AIAYSFTLAGENRRSGSNQANGQFEIILKPWSDRVDNDATVQKVMNEIKQSLHDVLE 655 + A S SG Q G + LKPW +R ++ + + V++ K L + + Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRD 659 Query: 656 AEFRIYLPSAVPGLGNGSGVEMELQDTSGSNFKGLMETADELVEALKLQP-EIATAGLSL 714 + A+ LG +G + EL D +G L + ++L+ P + + + Sbjct: 660 GFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNG 719 Query: 715 QSAIPQLHLNVDEAKAMAIGVKVSDIYGTIKTFTDSSTVNDFNLFGRVYRVKVQAEEQYR 774 Q L VD+ KA A+GV +SDI TI T + VNDF GRV ++ VQA+ ++R Sbjct: 720 LEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFR 779 Query: 775 QFPDQIEDYHVRSSSGAMVPIGVLAESNYSVGPAAVTHYNMFTSASINASPAPGYASGDV 834 P+ ++ +VRS++G MVP S++ G + YN S I APG +SGD Sbjct: 780 MLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDA 839 Query: 835 IRAIERVAKPMLPDEFSYEWTGITYQEVQSANQTAIAVTLAMVFVFLFLAALYESWTLPI 894 + +E +A LP Y+WTG++YQE S NQ V ++ V VFL LAALYESW++P+ Sbjct: 840 MALMENLASK-LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPV 898 Query: 895 AVLLIAPIAMLGASVGTLVSGMESNLFFQVAFIALIGMAAKNSILIVEFANQLH-KAGKS 953 +V+L+ P+ ++G + + +++++F V + IG++AKN+ILIVEFA L K GK Sbjct: 899 SVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKG 958 Query: 954 RLDSAIEAANMRFRPILMTSLAFILGVLPLVFSVGPGAVSRQSISIPILCGMIFATTIGI 1013 +++ + A MR RPILMTSLAFILGVLPL S G G+ ++ ++ I ++ GM+ AT + I Sbjct: 959 VVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAI 1018 Query: 1014 IMVPLFFV 1021 VP+FFV Sbjct: 1019 FFVPVFFV 1026 Score = 106 bits (266), Expect = 3e-25 Identities = 77/509 (15%), Positives = 179/509 (35%), Gaps = 29/509 (5%) Query: 5 FVNRPVFASVISIVIVLLGLIAMFQLPIDQYPYITPPQVKISASYPGATSTTAAESVATP 64 + +I +IV ++ +LP P P + + V Sbjct: 533 ILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQ 592 Query: 65 LEQEL-----NGLPNMIYMSSKSTNSGSSNITITF------DVGTNPDLAAVDAQNSTQQ 113 + + ++ ++ S + + N + F + + +A + + Sbjct: 593 VTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKM 652 Query: 114 ATGSLPIDVQTEGVSVSKEASVELL---KLALTSEDERYDEI-YLSNYATINIQSALKRI 169 G + + + A VEL D+ L+ + A + Sbjct: 653 ELGKIRDGF---VIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHP 709 Query: 170 PGVGRVRNTG-ARSYSMRVWLNPDTMAGYGLTTSDVIDAIKAQNKESPAGSIGSQPNADT 228 + VR G + ++ ++ + G++ SD+ I + + Sbjct: 710 ASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKK 769 Query: 229 LSMTLPITAAGRMSSVPQFNEIIVRASADGSIIRLRDIANIELGSSSYTLQSQLNGNNAT 288 L + +++ VR SA+G ++ S L + NG + Sbjct: 770 LYVQADAKFR---MLPEDVDKLYVR-SANGEMVPFSAFTTSHWVYGSPRL-ERYNGLPSM 824 Query: 289 ILQVYLLPGANALEVTKKVKAEMAKLAQKFPQGMNWEVFFDASVFIENSIDEVVKTLVEA 348 +Q PG + A M LA K P G+ ++ + S ++ + + Sbjct: 825 EIQGEAAPGT----SSGDAMALMENLASKLPAGIGYDWTGMSYQERL-SGNQAPALVAIS 879 Query: 349 LILVILVVFMFLQNIRATLIPAIAVPVSLIGTLAAMLAFGFTINTVSLLALVLAIGIVVD 408 ++V L + ++ + + VP+ ++G L A F + ++ L+ IG+ Sbjct: 880 FVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAK 939 Query: 409 DAIVVVENVERLMDEKGLSSSQATKVAMKELSGALIATSLVLAAVFVPVSFLSGITGIMY 468 +AI++VE + LM+++G +AT +A++ ++ TSL +P++ +G Sbjct: 940 NAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQ 999 Query: 469 REFAVAITVAVLISTVVALTLSPALCALL 497 + + ++ +T++A+ P ++ Sbjct: 1000 NAVGIGVMGGMVSATLLAIFFVPVFFVVI 1028 Score = 66.4 bits (162), Expect = 4e-13 Identities = 84/510 (16%), Positives = 181/510 (35%), Gaps = 52/510 (10%) Query: 538 YLLFALMVGGVYLTMSSLPSSFMPDEDQGRFFIDVSLPNGATVNRTQD-VLKKAEATVLA 596 ++L +++ L + LP + P + + P GA QD V + E + Sbjct: 13 WVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYP-GADAQTVQDTVTQVIEQNMNG 71 Query: 597 HPAIAYSFTLAGENRRSGSNQANGQFEIILKPWSDRVDNDATVQKVMNEIKQSLHDVLEA 656 + Y ++ + +GS F+ D D +V N+++ + Sbjct: 72 IDNLMY---MSSTSDSAGSVTITLTFQ-------SGTDPDIAQVQVQNKLQLATPL---- 117 Query: 657 EFRIYLPSAVPGLG-----NGSGVEMELQDTSGSNFKGLMETADELVEALKLQPEIAT-- 709 LP V G + S M S + + +D + +K ++ Sbjct: 118 -----LPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVK--DTLSRLN 170 Query: 710 --AGLSLQSAIPQLHLNVDEAKAMAIGVKVSDIYGTIKTFTDS----STVNDFNLFGRVY 763 + L A + + +D + D+ +K D L G+ Sbjct: 171 GVGDVQLFGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQL 230 Query: 764 RVKVQAEEQYRQFPDQIEDYHVRSS-SGAMVPIG-----VLAESNYSVGPAAVTHYNMFT 817 + A+ ++ + P++ +R + G++V + L NY+V + N Sbjct: 231 NASIIAQTRF-KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNV----IARINGKP 285 Query: 818 SASINASPAPGYASGDVIRAI-ERVA--KPMLPDEFSYEWTGITYQEVQSANQTAI-AVT 873 +A + A G + D +AI ++A +P P + T VQ + + + Sbjct: 286 AAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLF 345 Query: 874 LAMVFVFLFLAALYESWTLPIAVLLIAPIAMLGASVGTLVSGMESNLFFQVAFIALIGMA 933 A++ VFL + ++ + + P+ +LG G N + IG+ Sbjct: 346 EAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLL 405 Query: 934 AKNSILIVEFANQLHKAGKSR-LDSAIEAANMRFRPILMTSLAFILGVLPLVFSVGPGAV 992 ++I++VE ++ K ++ ++ + ++ ++ +P+ F G Sbjct: 406 VDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGA 465 Query: 993 SRQSISIPILCGMIFATTIGIIMVPLFFVT 1022 + SI I+ M + + +I+ P T Sbjct: 466 IYRQFSITIVSAMALSVLVALILTPALCAT 495
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 40.6 bits (95), Expect = 6e-06 Identities = 18/117 (15%), Positives = 48/117 (41%), Gaps = 12/117 (10%) Query: 65 KVVTRVAGLIQSIKVEEGDRVTKGQLLAVIDSKRQKFDLDRSQA------------EVEI 112 ++ +++ I V+EG+ V KG +L + + + D ++Q+ ++ Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILS 157 Query: 113 IEQELNRLKKINNKEFFSADSMAKLEYNLQAAIAKRDLAALYVQESMIRSPIEGVVA 169 ELN+L ++ + ++++ E ++ K + Q+ ++ A Sbjct: 158 RSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRA 214 Score = 39.8 bits (93), Expect = 1e-05 Identities = 40/192 (20%), Positives = 74/192 (38%), Gaps = 30/192 (15%) Query: 102 DLDRSQAEVEIIEQELNRLKK--INNKEFFSADSMAKL--------EYNLQAAIAKRDLA 151 +L ++++E IE E+ K+ + F + + KL L+ A + Sbjct: 267 ELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQ 326 Query: 152 ALYVQESMIRSPIEGVVATRFVKS-GNMAKEFDELFYVVNQDELYGI-VHLPEQQLQHLR 209 A S+IR+P+ V V + G + + L +V +D+ + + + + + Sbjct: 327 A-----SVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFIN 381 Query: 210 LGQDAQIFANKHTQETTH---ATVLRISP--IVDAQSGTF--------KVTLSVPNQNAA 256 +GQ+A I V I+ I D + G + LS N+N Sbjct: 382 VGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCLSTGNKNIP 441 Query: 257 LKAGMFTRVELK 268 L +GM E+K Sbjct: 442 LSSGMAVTAEIK 453
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 644 bits (1663), Expect = 0.0 Identities = 248/1100 (22%), Positives = 470/1100 (42%), Gaps = 96/1100 (8%) Query: 3 IIKTAVNRPVTVWMFMFAVILFGMVGFSRLAVKLLPDLSYPTITIRTQYVGAAPVEVEQL 62 + + RP+ W+ +++ G + +L V P ++ P +++ Y GA V+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 63 VSKPIEEAAGIVKGLRKISSISRS-GMSDVVLEFEWGTDMDMASLDVREKLDTIE--LPL 119 V++ IE+ + L +SS S S G + L F+ GTD D+A + V+ KL LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 120 DVKKPLLLRFNPNLDPIVRLALSVPETSESTTEGMSETELKQMRTYAEEELKRQLESLTG 179 +V++ + + ++ S G ++ ++ Y +K L L G Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFV------SDNPGTTQDDI---SDYVASNVKDTLSRLNG 171 Query: 180 VAAVRLSGGLQQEVHIQLNQQKLTQLNLSADLIRNRIAEENINLSAGKVIQGDK------ 233 V V+L G Q + I L+ L + L+ + N++ +N ++AG++ Sbjct: 172 VGDVQLFGA-QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQL 230 Query: 234 EYLVRTLNQFNSLEELGQIVIYRDEQ-TLVRLFEVAQIVDAHKERNDITRIGDKESIELA 292 + +F + EE G++ + + ++VRL +VA++ + N I RI K + L Sbjct: 231 NASIIAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLG 290 Query: 293 IYKEGDANTVAVAQKVTNELNKLNKHNAKA-ELKVIYDQSEFIESAVNEVTTAALIGSLL 351 I AN + A+ + +L +L + ++ YD + F++ +++EV +L Sbjct: 291 IKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIML 350 Query: 352 SMLVIYLFLRDIVPTLIISISIPFSVIATFNMMYFADISLNIMSLGGIALAVGLLVDNAI 411 LV+YLFL+++ TLI +I++P ++ TF ++ S+N +++ G+ LA+GLLVD+AI Sbjct: 351 VFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAI 410 Query: 412 VVLENIDRC-KSLGMNRLDAAVTGTKEVAGAIFASTLTTLAVFVPLVFVDGVAGALFSDQ 470 VV+EN++R + +A ++ GA+ + AVF+P+ F G GA++ Sbjct: 411 VVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQF 470 Query: 471 ALTVTFALLASLLVALTTIPMLASREGFKALPPLLEKTAKPKPETKMAKLKHYSATVFSF 530 ++T+ A+ S+LVAL P L + LL+ + E K Sbjct: 471 SITIVSAMALSVLVALILTPALCAT--------LLKPVSAEHHENK-------------- 508 Query: 531 PFVLLFNYLPSALLTLVLIIGRSLSWLTGLVMRPISGAFNWGYHKLERFYHKLLAAALKF 590 G FN + Y + L Sbjct: 509 --------------------------------GGFFGWFNTTFDHSVNHYTNSVGKILGS 536 Query: 591 KVLTLSIAIAVTAGAGLLIPRLGMELIPPMNQGEFYVEVLLPPGTEVTQTDRVLRTLALS 650 L I + AG +L RL +P +QG F + LP G +T +VL + Sbjct: 537 TGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDY 596 Query: 651 IKDRSDVKHAYSQAGSGGLMTSDTSRGGENWGRLQVVLQN-------HNAFDAVADKLRS 703 +++ + S G S ++ N G V L+ N+ +AV + + Sbjct: 597 YL-KNEKANVESVFTVNGFSFSGQAQ---NAGMAFVSLKPWEERNGDENSAEAVIHRAKM 652 Query: 704 TAMRIPE---LEAKMQHPELFSFKTPLEIELV---GYDLGQLKQTADNLVDALSDS-DRF 756 +I + + M T + EL+ G L Q + L+ + Sbjct: 653 ELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASL 712 Query: 757 ADINTSLRDGQPELSIRFDHERLAALGMDAPTVANRIAQRIGGTIASQYTVRDRKIDILV 816 + + + + + D E+ ALG+ + I+ +GGT + + R R + V Sbjct: 713 VSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYV 772 Query: 817 RSELDERNQISDIDSMIINPNSSHPISLSAVADVSLKLGPSAINRISQQRVAIVSANLAY 876 +++ R D+D + + + + SA G + R + + A Sbjct: 773 QADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAP 832 Query: 877 GDLNDAVLNARDILSAQTLPTSIQARFGGQNEEMEHSFKSLQIALVLAVFLVYLVMASQF 936 G + + + L+++ LP I + G + + S + ++ +V+L +A+ + Sbjct: 833 GTSSGDAMALMENLASK-LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALY 891 Query: 937 ESLLHPLLILIAVPMAVGGSILGLFITQTHLSVVVFIGLIMLAGIVVNNAIVLVDRINQL 996 ES P+ +++ VP+ + G +L + V +GL+ G+ NAI++V+ L Sbjct: 892 ESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDL 951 Query: 997 -RQDGEEKITAISNAAKSRLRPIIMTTMTTALGLSPMALGLGDGSEVRAPMAITVIFGLS 1055 ++G+ + A A + RLRPI+MT++ LG+ P+A+ G GS + + I V+ G+ Sbjct: 952 MEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMV 1011 Query: 1056 LSTLLTLVVIPVLYALFDRK 1075 +TLL + +PV + + R Sbjct: 1012 SATLLAIFFVPVFFVVIRRC 1031
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 486 bits (1252), Expect = e-157 Identities = 212/1054 (20%), Positives = 445/1054 (42%), Gaps = 79/1054 (7%) Query: 3 ITRFALARPVTTTMFFVAILLFGLASSRLLPLEMFPGIDIPQVIVEVPYKGSTPAEVERD 62 + F + RP+ + + +++ G + LP+ +P I P V V Y G+ V+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 63 ITNVLEESLATMGGIEELRSSSSQNG-AEIDLRMKWGQNVATKSLEAREKIDAVRHLLPK 121 +T V+E+++ + + + S+S G I L + G + ++ + K+ LLP+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 122 DVERVFIRQFSTADMPVLNLRISSDRELSSAFDLLD---KQLKKPLERVEGVSQVTLYGV 178 +V++ I ++ ++ SD ++ D+ D +K L R+ GV V L+G Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG- 179 Query: 179 EQKQIEIRINADKLSASNISVQSLNRRLQQENFVINAGVLKTDSRV------YQVSPKGE 232 Q + I ++AD L+ ++ + +L+ +N I AG L + + + Sbjct: 180 AQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 233 FRNLDDITALVLAPG-----ITLGDIANVSFSLPERLDGRHLDQNYAVGLDVFKESGANL 287 F+N ++ + L + L D+A V ++ A GL + +GAN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 288 VDVSQRVMKVINEAKRDSQFEGIKLFVMEDQAYGVTSSLRDLLTAGLIGALLSFVVLYLF 347 +D ++ + + E + +G+K+ D V S+ +++ +L F+V+YLF Sbjct: 300 LDTAKAIKAKLAELQPFFP-QGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLF 358 Query: 348 LRDLKMTLVIVSSVPIAICMTLAAMYFLGYSLNILSMMGLLLAVGMLIDNAVVVTESVLQ 407 L++++ TL+ +VP+ + T A + GYS+N L+M G++LA+G+L+D+A+VV E+V + Sbjct: 359 LQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 418 Query: 408 QKQAQIADGSAQEAGVAKINSSAILRGVDKVSLAVLAGTLTTAIVFLPNIFGVKVELTIF 467 A + + ++ A++ + + VF+P F I+ Sbjct: 419 VMMEDKLPPKE-----------ATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIY 467 Query: 468 LEHVAIAICISLAASLLVAKTLLPLMLSRMSFSQKKAPKK-------------SHLQARY 514 + +I I ++A S+LVA L P + + + + H Y Sbjct: 468 RQ-FSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHY 526 Query: 515 QTSLNWILAHPRISGVLAMVILASTALPLSMVKQDQSDGEGNNRLYINYQVEGRHSLDVT 574 S+ IL ++ +I+A + + E Q+ + + T Sbjct: 527 TNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERT 586 Query: 575 EAMITKMETYLYAN--KDEFQIDSVYSYFAADRGQS------TLILKEDTEVDMKALKKT 626 + ++ ++ Y N + + +V + + + Q+ +L E+ D + + Sbjct: 587 QKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAV 646 Query: 627 IREGFPKFAIAKPQFGWGGENNGVRVSLTGRST--------------TELIHLSEQVIPL 672 I + K + G+ N + G +T L Q++ + Sbjct: 647 IHRAKMEL--GKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGM 704 Query: 673 LS-NIDGLTDVRSELNGAQQEVVIRIDRQMAARLDLKLNEVASSISMALRGTPLRSFRHD 731 + + L VR + + +D++ A L + L+++ +IS AL GT + F D Sbjct: 705 AAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFI-D 763 Query: 732 PSGELRIEMAYEQQWRLSLEKLKQLPVIRIDNRVYTLDSLAKIEILPRFDTIRHYDRQTA 791 ++ + + ++R+ E + +L V + + + + + Y+ + Sbjct: 764 RGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPS 823 Query: 792 LSIGANLDE-LTTEEAQEKITQVMDSVNFPAGYGYSLRGGFQKQDEDEAVMATNMILAIA 850 + I ++ +A + + PAG GY G ++ + ++ Sbjct: 824 MEIQGEAAPGTSSGDAMALMENLAS--KLPAGIGYDWTGMSYQERLSGNQAPALVAISFV 881 Query: 851 MIYIVMAALFESLLLPTAIITSILFSITGVFWALLFTGTPMSIMAMIGILILMGIVVNNG 910 ++++ +AAL+ES +P +++ + I GV A + M+G+L +G+ N Sbjct: 882 VVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNA 941 Query: 911 IVLVDQINQLSPELDELSDTISAV---CYTRLRPVLMTVGTTVLGLVPLAMGDTQLGGGG 967 I++V+ L E + A RLRP+LMT +LG++PLA+ G G Sbjct: 942 ILIVEFAKDL--MEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAIS---NGAGS 996 Query: 968 PSYSPMAIAIIGGLTFSTVTSLYLVPLCYQALYR 1001 + + + I ++GG+ +T+ +++ VP+ + + R Sbjct: 997 GAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRR 1030
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 362 bits (932), Expect = e-124 Identities = 125/455 (27%), Positives = 212/455 (46%), Gaps = 43/455 (9%) Query: 38 CILADTLASANKAVQDYNFFVAIA--VLSKKTQHRVLNSVNEINQRQQNIIWIAVLIDID 95 + A+ + + + + + V+ + +L + + ++ ++ Sbjct: 30 VRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDLLPRIKKARPDLPVLV-MSAQNTFM 88 Query: 96 AVDAALISRLPYYFTDYHHLPIDWDHLNQTLGHAYGMAILKQKEQGGCRHLGQKTPFLGD 155 A Y DY P D L +G A +A K++ P +G Sbjct: 89 TAIKAS--EKGAY--DYLPKPFDLTELIGIIGRA--LAEPKRRPSKLEDDSQDGMPLVGR 142 Query: 156 SHLINKLRSNITKVAASDEAVLISGETGTGKGLCARLIHSQSARKRGPFITINCGALPQS 215 S + ++ + ++ +D ++I+GE+GTGK L AR +H R+ GPF+ IN A+P+ Sbjct: 143 SAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRD 202 Query: 216 LIHSELFGHEKGAFTGADKQYIGHIERANKGTLFLDEIGDLTLESQVNLLQFLEEHIIER 275 LI SELFGHEKGAFTGA + G E+A GTLFLDEIGD+ +++Q LL+ L++ Sbjct: 203 LIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTT 262 Query: 276 LGGNKTINIDCRIIFASHINLETAVEEGRFREDLYYRINILHLHAPSLREHKEDILLLAN 335 +GG I D RI+ A++ +L+ ++ +G FREDLYYR+N++ L P LR+ EDI L Sbjct: 263 VGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVR 322 Query: 336 EYLNLFSPEYQK-YTLSPKALDIMLAYEWPGNVRELKNRIHRGIIMANSDQLSAADLGIK 394 ++ E +AL++M A+ WPGNVREL+N + R + D ++ + + Sbjct: 323 HFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVITREIIENE 382 Query: 395 ITNIKPDENDVVDLAQHRVV---------------------------------IDTELLL 421 + + PD A+ + ++ L+L Sbjct: 383 LRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLIL 442 Query: 422 DAIKRNNHNISAAARELKISRTTFYRLIKKCKIKL 456 A+ N AA L ++R T + I++ + + Sbjct: 443 AALTATRGNQIKAADLLGLNRNTLRKKIRELGVSV 477
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 32.1 bits (73), Expect = 0.002 Identities = 26/125 (20%), Positives = 39/125 (31%), Gaps = 18/125 (14%) Query: 9 LALLLTPLLLTGCQPQNNAELQKEMASLKQEITQLKKEMSTIGGQVNDIHTIAMRSQKPQ 68 L L L+ ++L C + + + + I G D+H+I Q P Sbjct: 8 LVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIADITKNIAGDKIDLHSIVPIGQDPH 67 Query: 69 -YKTLPTQSNYGEDGKLPLQGD-ATAQLAIIEFSDYQCPYCKRFIDQTFTKLKSNYIDTG 126 Y+ PL D A + F Y + + FTKL N T Sbjct: 68 EYE--------------PLPEDVKKTSEADLIF--YNGINLETGGNAWFTKLVENAKKTE 111 Query: 127 KVQYL 131 Y Sbjct: 112 NKDYF 116
>CABNDNGRPT#NodO calcium binding signature. Length = 479 Score = 31.1 bits (70), Expect = 0.028 Identities = 14/45 (31%), Positives = 20/45 (44%) Query: 347 IGGSPSRAFINGSMTLRTVGHEMGHNLGLYHAKDYDCSEGVLTGR 391 S R + +T HE+GH LGL H +Y+ EG + Sbjct: 168 YNQSNIRNPGSEEYGRQTFTHEIGHALGLAHPGEYNAGEGDPSYN 212
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.0 bits (67), Expect = 0.016 Identities = 23/102 (22%), Positives = 39/102 (38%), Gaps = 5/102 (4%) Query: 70 EAETSKPDVNEQAPQFIEPVEEAFELSQAPAIKVNKTRVEPSLSAEAPAFTAEAPVQESL 129 +A T +V + + E + + K K +VE + E P T++ ++ Sbjct: 1077 KANTQTNEVAQSGSETKETQTTETKETATVE-KEEKAKVETEKTQEVPKVTSQVSPKQEQ 1135 Query: 130 FATDEPLLAEPVIEARQAPLDVAPQEPVVDEPKQVATEALGE 171 T +P AEP AR+ V +EP TE + Sbjct: 1136 SETVQP-QAEP---ARENDPTVNIKEPQSQTNTTADTEQPAK 1173
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 47.0 bits (111), Expect = 4e-07 Identities = 56/329 (17%), Positives = 103/329 (31%), Gaps = 6/329 (1%) Query: 168 AGISRYKERRRETENRIRHTRENLARLGDIRSELAKQLDKLAEQAETAKKYRELKQAERK 227 A + + E + L + L+K E A K + Sbjct: 123 ADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLE 182 Query: 228 CDAELSVSRYHELLQQIAKIDEQLGKLALQQAQFLAEKQTIELRLTELNLKLSELDTKEA 287 + +R EL + + + + AEK + R +L L Sbjct: 183 AEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFST 242 Query: 288 HQVEDFYLTKTHIAKLEQSLKHREQQDESLSLRLQEIAAQMQAYRARLAEDEAKQTLLNE 347 + A LE E+ E +A+++ A A EA++ L Sbjct: 243 ADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEH 302 Query: 348 QQASALPEASLLRQQLAEHDAELSTLVEQLEYLSEQLNSLNEAHT--QAHLAFEMNRNQL 405 Q LR+ L L + + L EQ + + L + Sbjct: 303 QSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQ 362 Query: 406 SHAETDISNKHKLVARLEDQALQ---TASDLELLKSQ-DITEQVSELSGVIEQEQEVLDE 461 AE + ++ Q+L+ AS + + + E S+L+ + + +E+ + Sbjct: 363 LEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEES 422 Query: 462 LNFLLEAKQQTEQTLFAEQDTLKVKLADE 490 + K + + L AE LK KLA + Sbjct: 423 KKLTEKEKAELQAKLEAEAKALKEKLAKQ 451 Score = 43.5 bits (102), Expect = 5e-06 Identities = 41/284 (14%), Positives = 106/284 (37%), Gaps = 4/284 (1%) Query: 616 EKTQAAGSIVELKNEQIALQQSVTNSQANLARLTESLTEIKLMVVPLVSQAQQKQQLIQA 675 ++ A I EL+ + L++++ + + + ++ L ++ ++ ++ Sbjct: 107 SLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEG 166 Query: 676 KQIELASLSSQLRSQQQSIVDIASRLAKVEQELVEAKQERQDFQLNVEQRKLQHQLLNET 735 + S+++++ + + +R A++E+ L A ++ + + L Sbjct: 167 AMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAAR 226 Query: 736 LEQTLRAKTQGQQQRALAAEKVAQLKPLRQQLDAKVTQTSLSEQGLHTQLVLIKQQVNQH 795 +A + K+ L+ + L+A+ + + +G ++ Sbjct: 227 KADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTL 286 Query: 796 EQRILELEQNERQLHKQLDAKDSAQEEGQSQPL---REQLDQALQAQQIKQEALTVLRRQ 852 E LE + L Q + A + + L RE Q Q +E + Sbjct: 287 EAEKAALEAEKADLEHQSQVLN-ANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEAS 345 Query: 853 QAELQELCDSAGTNKKQQLAKLEDLTQSSSTLKLRREGLKGQID 896 + L+ D++ KKQ A+ + L + + + R+ L+ +D Sbjct: 346 RQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLD 389 Score = 34.3 bits (78), Expect = 0.003 Identities = 34/245 (13%), Positives = 75/245 (30%), Gaps = 27/245 (11%) Query: 271 RLTELNLKLSELDTKEAHQVEDFYLTKTHIA------------------KLEQSLKHREQ 312 ++ E K + + D + K ++SL + Sbjct: 54 KVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKAS 113 Query: 313 QDESLSLRLQEIAAQMQAYRARLAEDEAKQTLLNEQQASALPEASLLRQQLAEHDAELST 372 + + L R ++ ++ D AK L ++A+ + L + L + Sbjct: 114 KIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTA 173 Query: 373 LVEQLEYLSEQLNSLNEAHTQAHLAFEMNRNQLSHAETDISNKHKLVARLEDQ------- 425 +++ L + +L + A E N + I A L + Sbjct: 174 DSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKA 233 Query: 426 --ALQTASDLELLKSQDITEQVSELSGVIEQEQEVLDELNFLLEAKQQTEQTLFAEQDTL 483 S + K + + + + L + ++ L+ A +TL AE+ L Sbjct: 234 LEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAAL 293 Query: 484 KVKLA 488 + + A Sbjct: 294 EAEKA 298 Score = 33.5 bits (76), Expect = 0.006 Identities = 36/304 (11%), Positives = 95/304 (31%), Gaps = 11/304 (3%) Query: 674 QAKQIELASLSSQLRSQQQSIVDIASRLAKVEQELVEAKQERQDFQLNVEQRKLQHQLLN 733 + Q + + + D++ ++ E +E + + + + Sbjct: 53 EKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKA 112 Query: 734 ETLEQTLRAKTQGQQQRALAAEKVAQLKPLRQQLDAKVTQTSLSEQGLHTQLVLIKQQVN 793 +++ K ++ A + L+A+ + + L L Sbjct: 113 SKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFST 172 Query: 794 QHEQRILELEQNERQLHKQLDAKDSAQEEGQSQPLREQLDQALQAQQIKQEALTVLRRQQ 853 +I LE L+A+ + E+ + + + L ++ Sbjct: 173 ADSAKIKTLEAE----KAALEARQAELEK-ALEGAMNFSTADSAKIKTLEAEKAALAARK 227 Query: 854 AELQELCDSAGTNKKQQLAKLEDLTQSSSTLKLRREGLKGQIDSQLRLLNEQRVDVELIL 913 A+L++ + A AK++ L + L+ R+ L+ ++ + ++ + Sbjct: 228 ADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLE 287 Query: 914 STLDDKKTMLWRQKELERLREQIGLLGAINLAAIEEYDQQNQRKLYLDSQDDDLNAALSS 973 + + E L Q +L A + + D + K L+++ L Sbjct: 288 AEKAAL------EAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKI 341 Query: 974 LEEA 977 E + Sbjct: 342 SEAS 345 Score = 30.8 bits (69), Expect = 0.040 Identities = 43/267 (16%), Positives = 92/267 (34%), Gaps = 9/267 (3%) Query: 616 EKTQAAGSIVELKNEQIALQQSVTNSQANLARLTESLTEIKLMVVPLVSQAQQKQQLIQA 675 EK EL+ T A + L + L + A Sbjct: 184 EKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTA 243 Query: 676 KQIELASLSSQLRSQQQSIVDIASRLAKVEQELVEAKQERQDFQLNVEQRKLQHQLLNET 735 ++ +L ++ + + ++ L + + + + + L Sbjct: 244 DSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQ 303 Query: 736 LEQTLRAKTQGQQQRALAAEKVAQLKPLRQQLDAKVTQTSLSEQGLHTQLVLIKQQVNQH 795 + + ++ + E QL+ Q+L+ + + S Q L L ++ Q Sbjct: 304 SQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQL 363 Query: 796 EQRILELEQN------ERQ-LHKQLDAKDSAQE--EGQSQPLREQLDQALQAQQIKQEAL 846 E +LE+ RQ L + LDA A++ E + +L + + +E+ Sbjct: 364 EAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESK 423 Query: 847 TVLRRQQAELQELCDSAGTNKKQQLAK 873 + +++AELQ ++ K++LAK Sbjct: 424 KLTEKEKAELQAKLEAEAKALKEKLAK 450
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 63.7 bits (155), Expect = 4e-13 Identities = 24/112 (21%), Positives = 47/112 (41%), Gaps = 3/112 (2%) Query: 120 QSVKVLVADDSVVSRKFIRSLLEQHLFQVIEADDGISALETLNDNPDITLLITDYNMPRL 179 +LVADD R + L + + V + + + L++TD MP Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGD-GDLVVTDVVMPDE 60 Query: 180 DGFGLIIKVRERLGREELAIIGLSSDSDESLSARFIKNGANDFLQKPFVHEE 231 + F L+ ++++ + ++ + ++ A + GA D+L KPF E Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKA--SEKGAYDYLPKPFDLTE 110 Score = 57.1 bits (138), Expect = 5e-11 Identities = 22/116 (18%), Positives = 51/116 (43%), Gaps = 5/116 (4%) Query: 2 RILVVEDSQVVSRVMRHLLTQELCCEVDVASDMASAKELLAHNEYFVAITDLNLPDAQEG 61 ILV +D + V+ L++ +V + S+ A+ +A + + +TD+ +PD Sbjct: 5 TILVADDDAAIRTVLNQALSRA-GYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 EIVKFVLE--KQIPCIVLTGSWDAEQRARLLQLGIVDYVFKENRFSYEYTAKLVKR 115 +++ + + +P +V++ + + G DY+ K F ++ R Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKP--FDLTELIGIIGR 117
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 42.3 bits (99), Expect = 4e-07 Identities = 15/57 (26%), Positives = 27/57 (47%) Query: 11 QSSRSDGQARRIAILEATLRLIVREGIRGVRHRAVASEANVPLSSTTYYFDDIKDLI 67 + ++ + Q R IL+ LRL ++G+ +A A V + ++F D DL Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLF 59
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.8 bits (67), Expect = 0.008 Identities = 26/156 (16%), Positives = 61/156 (39%), Gaps = 18/156 (11%) Query: 42 EVRSTSAKVLAEKKEIIRR-IAKVQEQVQDWESKAELALSKDREDLAKAALVEKQKANEL 100 + A++ + +I+ R I + + + E L +L+++Q + Sbjct: 140 QSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQ 199 Query: 101 AQ---------TLAAELVVVEEHILRLKEEVNLLQEKLADAKARQKTIIMRKQTASSRLE 151 Q AE + V I R + + + +L D + + + A ++ Sbjct: 200 NQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSS------LLHKQAIAKHA 253 Query: 152 VKKQLDSSKIDNAMSKFEQYERRVENLESQVDSYDL 187 V +Q +K A+++ Y+ ++E +ES++ S Sbjct: 254 VLEQ--ENKYVEAVNELRVYKSQLEQIESEILSAKE 287
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 353 bits (908), Expect = e-121 Identities = 113/353 (32%), Positives = 185/353 (52%), Gaps = 9/353 (2%) Query: 6 QQDNLIGQSNALLEVLEHISQVAPLSKPVLIIGERGTGKELIAERLHYLSKRWDQSFIKL 65 L+G+S A+ E+ ++++ ++I GE GTGKEL+A LH KR + F+ + Sbjct: 135 DGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAI 194 Query: 66 NCSSLSENLLESELFGHDAGAFTGASKKHEGRFERADGGTLFLDELANTSGLIQEKLLRV 125 N +++ +L+ESELFGH+ GAFTGA + GRFE+A+GGTLFLDE+ + Q +LLRV Sbjct: 195 NMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRV 254 Query: 126 IEYGEFERVGGSKTVQTNVRLICAANEDLPSLAEAGEFRPDLLDRLAFDVITLPPLRHRS 185 ++ GE+ VGG ++++VR++ A N+DL G FR DL RL + LPPLR R+ Sbjct: 255 LQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRA 314 Query: 186 EDIMALAEYFAVGMARQLKLELFEGFSRSAVEQLMEYQWPGNIRELKNVVERSVYRNADT 245 EDI L +F ++ F + A+E + + WPGN+REL+N+V R Sbjct: 315 EDIPDLVRHFVQQAEKEGLDVK--RFDQEALELMKAHPWPGNVRELENLVRRLTALYPQ- 371 Query: 246 NAAIEQIIIDPFASPYRPTKRVKTKERQQIVSPEVNVTAPDSTTEVSANTSTLANAAVSF 305 + I + + R + ++ + +++ + E A+ Sbjct: 372 ----DVITREIIENELRSE--IPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPP 425 Query: 306 PIDFKTHCEQGEVRILKQALEAGQFNQKKTAELLGLSYHQLRGILKKYNLLDK 358 + + E ++ AL A + NQ K A+LLGL+ + LR +++ + Sbjct: 426 SGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVSVY 478
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.2 bits (68), Expect = 0.011 Identities = 9/16 (56%), Positives = 14/16 (87%) Query: 38 LVGESGSGRTLLARAI 53 + GESG+G+ L+ARA+ Sbjct: 165 ITGESGTGKELVARAL 180
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.7 bits (66), Expect = 0.013 Identities = 12/50 (24%), Positives = 19/50 (38%), Gaps = 1/50 (2%) Query: 43 LAIVGEAGSGKSTIARILVGAEIRSGGEIFFEGEPLDKHDLKQRCRLIRM 92 + + G G GKST+ LVG + S G D ++ + Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDI-GTGKDSYEQIAGIVAYEL 647
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 118 bits (298), Expect = 6e-39 Identities = 50/88 (56%), Positives = 67/88 (76%) Query: 2 NKSELIEKIASGADISKAAAGRALDSFIGAVTDGLKEGDKIALVGFGTFEVRQRAERTGR 61 NK +LI K+A +++K + A+D+ AV+ L +G+K+ L+GFG FEVR+RA R GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 62 NPQTGKEIKIAAANIPAFKAGKALKDAV 89 NPQTG+EIKI A+ +PAFKAGKALKDAV Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAV 90
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 34.4 bits (79), Expect = 0.002 Identities = 28/152 (18%), Positives = 60/152 (39%), Gaps = 26/152 (17%) Query: 304 HKRSKIKRDLAKAQDVLD--TDHFGLEKVKERILEYLAVQSRVKQLKGPILCLVGPPGVG 361 + + + +QD + ++++ + +R+ Q ++ + G G G Sbjct: 121 EPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVL-------ARLMQTDLTLM-ITGESGTG 172 Query: 362 KTSLGQSIAKATGRK---YVRVALGGVRD---EAEIRGHRRTYIGSMPGKVIQKMSKVGV 415 K + +++ R+ +V + + + E+E+ GH + G+ G + + Sbjct: 173 KELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEK---GAFTGAQTRSTGRFEQ 229 Query: 416 KN--PLFLLDEIDKMSSDMRGDPASALLEVLD 445 LFL DEI M D + + LL VL Sbjct: 230 AEGGTLFL-DEIGDMPMDAQ----TRLLRVLQ 256
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.8 bits (67), Expect = 0.021 Identities = 14/74 (18%), Positives = 30/74 (40%), Gaps = 13/74 (17%) Query: 60 QDQDKLPTPHELRAHLDDYVIGQDKAKKVLAVAVYNHYKRLRNATPKDGVELGKSNILLI 119 + + P+ E + ++G+ A + + Y+ L D +++ Sbjct: 120 AEPKRRPSKLEDDSQDGMPLVGRSAAMQEI-------YRVLARLMQTD------LTLMIT 166 Query: 120 GPTGSGKTLLAETL 133 G +G+GK L+A L Sbjct: 167 GESGTGKELVARAL 180
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.4 bits (66), Expect = 0.028 Identities = 9/32 (28%), Positives = 19/32 (59%) Query: 325 MNAYLLHFGDLQQCANVLFIHRNTLRYRLDRI 356 + A G+ + A++L ++RNTLR ++ + Sbjct: 442 LAALTATRGNQIKAADLLGLNRNTLRKKIREL 473
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 43.3 bits (102), Expect = 5e-08 Identities = 20/54 (37%), Positives = 37/54 (68%), Gaps = 4/54 (7%) Query: 8 KNGFTLIELVVVIIVLGILAVIALPKFVNF--HADSKVAVLDGIAGAMKSGLDL 59 + GFTL+E++VVI+++G+LA + +P + AD + AV D + A+++ LD+ Sbjct: 7 QRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIV--ALENALDM 58
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 151 bits (382), Expect = 3e-45 Identities = 82/337 (24%), Positives = 133/337 (39%), Gaps = 53/337 (15%) Query: 21 AVAAKSFYSDGDFYFGGKLGGVLLDSEEPLEPGENKMVN-LSSGLTLGYNINSYLSVETD 79 A A++ D +Y G KLG + N L +G GY +N Y+ E Sbjct: 16 ATVAQAAPKDNTWYTGAKLGWSQYHDTGFINNNGPTHENQLGAGAFGGYQVNPYVGFEMG 75 Query: 80 MSYLGQYQDELSGEDKNLFAIGASLS--TRYRLSDDAALYVKLGPAWVEDN--------- 128 +LG+ + S E+ A G L+ Y ++DD +Y +LG + Sbjct: 76 YDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPITDDLDIYTRLGGMVWRADTKSNVYGKN 135 Query: 129 ----VSLSSGLGIKYRLSPNWELDSGYRWI-----KDTPSTDDDLYEFTLGINYKFGVVS 179 VS G++Y ++P Y+W T T D +LG++Y+FG Sbjct: 136 HDTGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDAHTIGTRPDNGMLSLGVSYRFGQGE 195 Query: 180 HQPVRPAVEPTLKHKKKVELLDATSTTAITVSKPVSISAKSLFGFDSSKLVATEALAEVL 239 PV A P + +K ++ + LF F+ + L L Sbjct: 196 AAPV-VAPAP--------------APAPEVQTKHFTLKSDVLFNFNKATL--KPEGQAAL 238 Query: 240 KNVIA------SKDTEICITAYTDSLGAKEYNLTLSKQRAEATRSYFISNGVEPSRIHVD 293 + + KD + + YTD +G+ YN LS++RA++ Y IS G+ +I Sbjct: 239 DQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPADKISAR 298 Query: 294 WKGEASPVATNRTAEGR---------ALNRRVKIELN 321 GE++PV N + A +RRV+IE+ Sbjct: 299 GMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVK 335
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 56.0 bits (135), Expect = 5e-10 Identities = 70/476 (14%), Positives = 142/476 (29%), Gaps = 91/476 (19%) Query: 285 RIEVYRDGHLIYSKNVDAGQQSIAFRDLPYGSYTASIVVI---SAGREILKERQQIVN-- 339 ++ + ++G+ IY+ V G +I D+ + + V + G + V Sbjct: 310 QVTIKQNGYDIYNSTVPPGPFTI--NDIYAAGNSGDLQVTIKEADGS----TQIFTVPYS 363 Query: 340 NSAFSLNKGEYDYSFSAGRFNDRYDNSYDGGVEQSQLTKIQAKLGYLVGPDSFIQADGFI 399 + +G YS +AG + + + F Q Sbjct: 364 SVPLLQREGHTRYSITAGEY-RSGNAQQEK--------------------PRFFQ----- 397 Query: 400 HDGDYSYKRTGGLNAYLKTL-TEPYS---LQLESNNFVEGKLSYQLTDSTMIGGRILSNS 455 + G Y T + Y + N G LS +T + + +S Sbjct: 398 --STLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQAN---STLPDDS 452 Query: 456 DSTLSELGVKTSLSDDST-AQLKFAS-------FSNGSQFIAADVSFYNIGVGYEKFDSA 507 + + S + + ++ + N + + ++ YNI + Sbjct: 453 QHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNI--ETQDGVIQ 510 Query: 508 DSDFGLDNFMLSNTGYQRLNVNLSSDLWGGQGYVLYVNNKLDAENEAQPFLDQSDYW--- 564 D + L+ +L + ++ L G LY++ YW Sbjct: 511 VKPKFTDYYNLAYNKRGKLQLTVTQQL-GRTST-LYLS------------GSHQTYWGTS 556 Query: 565 ----SVSAGFSHSFVADSVINFSATFQGGESFGVKDDWYASVLW-SVPLSAGWSASS--- 616 AG + +F IN++ ++ ++ K L ++P S + S Sbjct: 557 NVDEQFQAGLNTAF---EDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQ 613 Query: 617 --SVSVSRQGLDEFRNSVANDRQLSRNLSMNNELGISYNGTDIERNMSSDLSS---NINY 671 S S + + N + L +N L S + S+ +NY Sbjct: 614 WRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNY 673 Query: 672 NNGYVASDTYAYISSDGTHSVSSSFNSTQVLSGKGEVYFSSEQSDAYIIVDAQNQG 727 GY ++ S D + + + G V +D ++V A Sbjct: 674 RGGYGNANIGYSHSDDIK-QLYYGVSGGVLAHANG-VTLGQPLNDTVVLVKAPGAK 727 Score = 34.1 bits (78), Expect = 0.003 Identities = 41/329 (12%), Positives = 94/329 (28%), Gaps = 35/329 (10%) Query: 428 ESNNFVEGKLSYQLTDSTMIGGRILSNSDSTLSELGVKTSLSDDSTAQLKFASFSNGSQF 487 E F + L + L I G G+ ++ + + +N + Sbjct: 391 EKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVD-MTQANSTLP 449 Query: 488 IAADVSFYNIGVGYEK-FDSADSDFGLDNFMLSNTGYQRLNVNLSSDLWGGQGYVLYVNN 546 + ++ Y K + + ++ L + S +GY S + G Sbjct: 450 DDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGVI 509 Query: 547 KLDAENEAQPFLDQSDYWSVSAGFSHSFVADSVINFSATFQGGESFGVKDDWYASVLWSV 606 ++ + L + + + S + S + Q ++ + Sbjct: 510 QVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQ---------TYWGTSNVDE 560 Query: 607 PLSAGWS-----ASSSVSVSRQGLDEFRNSVANDRQLSRNLSMNNELGISYNGTDIERNM 661 AG + + ++S S + ++ D+ L+ N+++ + + R+ Sbjct: 561 QFQAGLNTAFEDINWTLSYSLT-KNAWQKG--RDQMLALNVNIPFSHWLRSDSKSQWRHA 617 Query: 662 SSDLSSNINYNNGYVASDTY----------------AYISSDGTHSVSSSFNSTQVLSGK 705 S+ S + + N Y +S S+ + + G Sbjct: 618 SASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGY 677 Query: 706 GEVYFSSEQSDAYIIVDAQNQGSDDAHRG 734 G SD + G AH Sbjct: 678 GNANIGYSHSDDIKQLYYGVSGGVLAHAN 706
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 188 bits (479), Expect = 3e-58 Identities = 93/372 (25%), Positives = 159/372 (42%), Gaps = 28/372 (7%) Query: 42 SWLEVNLTQFDSNIKELKNHIQSNVKVCAIMKADAYGNGIAGLMPTVLANNIPCIGVTSN 101 ++L N+ ++ + +V +++KA+AYG+GI + + A + + + Sbjct: 5 IQASLDLQALKQNLSIVRQAAT-HARVWSVVKANAYGHGIERIWSAIGATD--GFALLNL 61 Query: 102 EEIRIVRDAGFRGSLIRVRSASIAEISDTL-QYDVEEFVGDANQATLLSAMAAKLDKPLK 160 EE +R+ G++G ++ + A+ + Q+ + V Q L A+L PL Sbjct: 62 EEAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQN--ARLKAPLD 119 Query: 161 VHLVLNSGGMGRNGVDVSTQSGLNEAVQIATTADLDVVGIMTHFPSYDRDDVLVKSKSFY 220 ++L +NSG M R G L Q+ A++ + +M+HF + D Sbjct: 120 IYLKVNSG-MNRLGF--QPDRVLTVWQQLRAMANVGEMTLMSHFAEAEHPD-------GI 169 Query: 221 NSALNIIEESGLKRDSVTIHSGNSYVALNVPEAHFDMVRPGGVLYGDQPT-------NPE 273 + A+ IE++ + S NS L PEAHFD VRPG +LYG P+ N Sbjct: 170 SGAMARIEQAAEGLECRRSLS-NSAATLWHPEAHFDWVRPGIILYGASPSGQWRDIANTG 228 Query: 274 FPSIVTFKTRIASLVDLPKGATVGYDSTIKLERESLLANLPVGYSDSFPRKMGNTADVLV 333 ++T + I + L G VGY E + + GY+D +PR VLV Sbjct: 229 LRPVMTLSSEIIGVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAPTGTPVLV 288 Query: 334 NGQRAKVMGVISMNTSMIDVTDLSGVKEGDEVVLFGYQGKESILAPEFEKNADVIFPEIY 393 +G R +G +SM+ +D+T G V L+G + I + A + E+ Sbjct: 289 DGVRTMTVGTVSMDMLAVDLTPCPQAGIGTPVELWG----KEIKIDDVAAAAGTVGYELM 344 Query: 394 TQWGQTNPRIYV 405 P + V Sbjct: 345 CALALRVPVVTV 356
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 67.7 bits (165), Expect = 4e-16 Identities = 28/179 (15%), Positives = 57/179 (31%), Gaps = 14/179 (7%) Query: 1 METKSKTRGRPKQSPVHTPCQQNILSVARRLFLTFSYSKVTTRKIADEADVDVALIGYYF 60 M K+K + + Q+IL VA RLF S + +IA A V I ++F Sbjct: 1 MARKTKQEAQETR--------QHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHF 52 Query: 61 GSKAELYKAVFDDIYAPFFEKLNQL--KQASSEINTIEELFMTIFNLDIEHP--ELLSII 116 K++L+ +++ + E + K ++ + E+ + + + LL I Sbjct: 53 KDKSDLFSEIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEI 112 Query: 117 YKTLVLNDG--PKRNYFNKQILNYTDTFHVNIFAKLQRDGFIDKNLDVELLKDSFNALV 173 G + + + + +L + Sbjct: 113 IFHKCEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYI 171
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 33.9 bits (78), Expect = 0.002 Identities = 18/72 (25%), Positives = 32/72 (44%), Gaps = 12/72 (16%) Query: 31 DLKLTNVSLLDLINGEVIPGPILIDKGHIIAVGQE--------VDLL--AAVRVVDCHGQ 80 D +TN +LD ++ I + G I A+G+ V ++ V+ G+ Sbjct: 69 DTVITNALILDHWG--IVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGK 126 Query: 81 IAVPGFIDAHMH 92 I G +D+H+H Sbjct: 127 IVTAGGMDSHIH 138
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 277 bits (709), Expect = 2e-80 Identities = 108/589 (18%), Positives = 221/589 (37%), Gaps = 50/589 (8%) Query: 92 PMGASGPTAEAEDNMC--SSELANLSGEALFDAVRQAEISCISELYSRNDAVSVAAYQTE 149 P+G S + A +N EL ++ L + ++ + +L++ ND + Sbjct: 77 PLGPSIAPSRARNNKIYTFDELNRMNYSDLVELIKTISYENVPDLFNFNDGSYTFFSNRD 136 Query: 150 NVVSVANQAAAIAATYDSSTGYEMRNLFYFLRGAFYIEFYNDDLAYSDTQA-ADAVYAAL 208 V ++ TY + + L FLR +Y+ FYN L+Y +T + A+ Sbjct: 137 RVQAIIYGLEDSGRTYTADDDKGIPTLVEFLRAGYYLGFYNKQLSYLNTPQLKNECLPAM 196 Query: 209 VEYAKNPKLFEITPSAGDTLMEFFTSWASSDHILESVPVITDYLQMFNADFLASNRHRAA 268 N T + + ++ E + L F + + + Sbjct: 197 KAIQYNSNFRLGTKAQDGVVEALGRLIGNASADPEVINNCIYVLSDFKDNIDKYGSNYSK 256 Query: 269 MTSALTTLYYGSW---EEAYNSKAMEH---------GELIDALLNIATADYIINSDYQYE 316 + + + YN+K + ++ L ++ T +N+D + Sbjct: 257 GNAVFNLMKGIDYYTNSVIYNTKGYDAKNTEFYNRIDPYMERLESLCTIGDKLNNDNAWL 316 Query: 317 STDAFHEFGRFYEYQKYWDLPQSLKTRLNDGVELYMSKFERMSAQ---WADGAGYLDYYN 373 +A + GR ++++ + Q R M ++ +S Q A+ Sbjct: 317 VNNALYYTGRMGKFREDPSISQRALERA-------MKEYPYLSYQYIEAANDLDLNFGGK 369 Query: 374 PGDCEQFGICGWEEELEQTALPINYSCSDTIYI-RAQQLTNDE-LQSSCDLMGGEETLFH 431 + + + LP Y+ D ++ +A +E ++ + F Sbjct: 370 NSSGNDIDFNKIKADAREKYLPKTYTFDDGKFVVKAGDKVTEEKIKRLYWASKEVKAQFM 429 Query: 432 DVLATGYQPVADDLNESLEVNIFDSYDDYAQYASVIFGINTNNGGMYLEGTPSQEGNHAR 491 V+ + ++ L V I++S ++Y + +I G +T+NGG+Y+E N Sbjct: 430 RVVQNDKALEEGNPDDILTVVIYNSPEEY-KLNRIINGFSTDNGGIYIE-------NIGT 481 Query: 492 FIAHEATWTDEI-LVWNL-KHEYVHYLDGRFNLYGAF-NYFDIDTGKSVWWTEGLAEYIS 548 F +E T + I + L +HE+ HYL GR+ + G + G W+ EG AE+ + Sbjct: 482 FFTYERTPEESIYTLEELFRHEFTHYLQGRYVVPGMWGQGEFYQEGVLTWYEEGTAEFFA 541 Query: 549 KQNRNDG---------AIELGRSQAYSLSEILSNTYDSGSDRVYSWGYLAVRFLFENHRS 599 R DG + R+ SL +L Y S Y++G+ +++ N+ Sbjct: 542 GSTRTDGIKPRKSVTQGLAYDRNNRMSLYGVLHAKYGS--WDFYNYGFALSNYMYNNNMG 599 Query: 600 DVDALLVLARGGDADGWLAYIDNTIGQ-NYNSEWNTWLASVSSNDDSIS 647 + + + D G+ YI + N ++ ++ S+ +N D++ Sbjct: 600 MFNKMTNYIKNNDVSGYKDYIASMSSDYGLNDKYQDYMDSLLNNIDNLD 648 Score = 79.4 bits (195), Expect = 5e-17 Identities = 34/244 (13%), Positives = 73/244 (29%), Gaps = 32/244 (13%) Query: 454 FDSYDDYA-QYASVIFGINTNNGGMYLEGTPSQEGNHARFIAHEATWTDEILVWNLKHEY 512 + S+D Y +A + N N G + + ++ + L +Y Sbjct: 577 YGSWDFYNYGFALSNYMYNNNMGMFNKMTNYIKNND---VSGYKDYIASMSSDYGLNDKY 633 Query: 513 VHYLDGRFNLYGAFNYFDIDTGKSVWWTEGLAEYISKQNRNDGAIE-LGRSQAYSLSEIL 571 Y+D N D+ + A+ I++ + + + + Sbjct: 634 QDYMDSLLNNIDNL---DVPLVSDEYVNGHEAKDINEITNDIKEVSNIKDLSSNVEKSQF 690 Query: 572 SNTYDSGSDRVYSWGYLAVRFLFENH-----RSDVDALLVLARGGDADGWLAYI------ 620 TYD Y+ R E + S ++ +L +G+ Sbjct: 691 FTTYD------MRGTYVGGRSQGEENDWKDMNSKLNDILKELSKKSWNGYKTVTAYFVNH 744 Query: 621 --DNTIGQNYNSEWNTWLASVSSNDDSISTGITPPVDSDGDGVIDSQDAFPHDPSETHDT 678 D Y+ ++ ++ D ++ + SD +++ + F T Sbjct: 745 KVDGNGNYVYDVVFHGMNTDTNT-DVHVNKEPKAVIKSDSSVIVEEEINF----DGTESK 799 Query: 679 DGDG 682 D DG Sbjct: 800 DEDG 803
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 110 bits (277), Expect = 6e-27 Identities = 93/672 (13%), Positives = 197/672 (29%), Gaps = 84/672 (12%) Query: 95 AQKGLDLSFNPSTLTLDLEIDPEAFGQFDVDFNNQFNAFVP----SQSGTFSWLN-SINF 149 + L+L I N+ ++P LN + + Sbjct: 141 MIHDATAQLDVGQQRLNLTIPQAFMS-------NRARGYIPPELWDPGINAGLLNYNFSG 193 Query: 150 THSENWESTTNSRFSTADWLAQMNFGGA---NGINITLANHLEANDSETNLLRGEWTAFY 206 +N NS ++ + + +N G + + + ++ S+ Sbjct: 194 NSVQN-RIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLER 252 Query: 207 DRPSAPFRLAMGDVESGSSVAGHLSGTSMGGLSIKSDYAELQPERIIGPNNSQELILKES 266 D RL +GD + + G + G + SD + P+ G I + + Sbjct: 253 DIIPLRSRLTLGDGYTQGDI---FDGINFRGAQLASDDN-MLPDSQRGFAPVIHGIARGT 308 Query: 267 AEVEITVNGQIIFSGRQEAGRFNLNNLPMTNGANDIIVNVTYLSGKSERFVFSQFYNNKL 326 A+V I NG I++ G F +N++ + D+ V + G ++ F L Sbjct: 309 AQVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLL 368 Query: 327 LNKDMLNFGVTAGAPSIYAENGVEYLDTWTVIGFTEYGVSSWLTLGANAAIAQYGQILGA 386 + + +TAG Y + +G+ + T+ +A + Sbjct: 369 QREGHTRYSITAGE---YRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNF 425 Query: 387 TATLGT-SWGNLSSRVSFSNL----EDTGMGNIVSFTFES---------TVAGNSNNAPN 432 + G LS ++ +N + G V F + + G + Sbjct: 426 GIGKNMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSG 485 Query: 433 LRLSADFSDTFTSSPWDK--DILATSYERYLANYVWIFNNAWDTTISGSY---------- 480 AD + + + + D + ++ Y +N ++ + Sbjct: 486 YFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYL 545 Query: 481 ------YKDTHDVEQS-NLSMTLNWRMGDWTVGTGANYNDTDTYENADIEYFVTLDWRRS 533 Y T +V++ + + +WT+ N + + V + + Sbjct: 546 SGSHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHW 605 Query: 534 NTQNKVNLAANYNSANNYARLEASKTS-----SDRVGS---IGYRAQAEYEDGRDSQNAQ 585 + + + +++ + + + + + + Y Q Y G D + Sbjct: 606 LRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGS 665 Query: 586 F---DYTANRLRVELEVERNNSNASIDNDA-SYSASIRGNTAIGIVDGQVGWGRAQDGPF 641 N S +D + G + V G+ + Sbjct: 666 TGYATLNYRGGYGNA-----NIGYSHSDDIKQLYYGVSG--GVLAHANGVTLGQPLNDTV 718 Query: 642 IISKLHPSLPQQQVMLGIDQKQNYEASGTSMIG-ALLPLEVAYVSNVVDLNVPDAPIGYD 700 ++ K P +V +N T G A+LP Y N V L+ D Sbjct: 719 VLVKA-PGAKDAKV-------ENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVD 770 Query: 701 WGESRLTVSPGA 712 + V P Sbjct: 771 LDNAVANVVPTR 782
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 46.2 bits (109), Expect = 4e-08 Identities = 36/165 (21%), Positives = 69/165 (41%), Gaps = 10/165 (6%) Query: 6 AIIVGASSLLSREIAKQLADEGVELALLAQDPQSLIEFSQSLPTKA---QVFPLQIDEPE 62 A I GA+ + +A+ LA +G +A + +P+ L + SL +A + FP + + Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSA 70 Query: 63 AIISTLNAVWQSLGGAHLILVNTGLTHYDP--ELPWQPEQDIITVNVQGFSAICNTAFRL 120 AI + + +G +++ G+ L + + +VN G + + Sbjct: 71 AIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSKY 130 Query: 121 FRDQGYGQLAAINSIAGLRGGPSV---AYHASKAYAQNYFEGLSM 162 D+ G + + S G P AY +SKA A + + L + Sbjct: 131 MMDRRSGSIVTVGSNPA--GVPRTSMAAYASSKAAAVMFTKCLGL 173
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 52.5 bits (126), Expect = 1e-09 Identities = 37/188 (19%), Positives = 78/188 (41%), Gaps = 21/188 (11%) Query: 103 SVQAAQLKEQEVQLPAVRDDYNRQLRLYKDKSISQQSLQAAQAKYEALQANIESLQANIE 162 V +QL++ E ++ + +++Y +L+K++ + + L+ L + + + Sbjct: 269 RVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDK--LRQTTDNIGLLTLELAKNEERQQ 326 Query: 163 LRQIKAPFNG-VLGIRNINLGQFLSAGTN---IVRLEDLSVMRVRFSVPQSQIGKLSVGQ 218 I+AP + V ++ G ++ IV +D + V V IG ++VGQ Sbjct: 327 ASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDD--TLEVTALVQNKDIGFINVGQ 384 Query: 219 PISLTVDPYPDRIY---SGKINAIEP--VINYKTGLV------MIQAELPNDDQT--LRG 265 + V+ +P Y GK+ I + + + GLV + + L ++ L Sbjct: 385 NAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCLSTGNKNIPLSS 444 Query: 266 GMFAEVSV 273 GM + Sbjct: 445 GMAVTAEI 452
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 797 bits (2059), Expect = 0.0 Identities = 319/1030 (30%), Positives = 540/1030 (52%), Gaps = 34/1030 (3%) Query: 7 FIHRPVMAASLSILLFILGLNAMKDLQVRQYPEMTNTVITVTTPYPGADAELIEGFITQP 66 FI RP+ A L+I+L + G A+ L V QYP + ++V+ YPGADA+ ++ +TQ Sbjct: 5 FIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQV 64 Query: 67 LEQALSQVDNLDFMTSSSQ-LGTSTIILNMRLNTNPEEALANVLSQINSVTNQLPKEAYN 125 +EQ ++ +DNL +M+S+S G+ TI L + T+P+ A V +++ T LP+E Sbjct: 65 IEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQQ 124 Query: 126 PSVTSSTGATTSIMYISFFSKELDSSQ--IVDYLERVVNPQLSTVNGVSNIQMMGGTPFA 183 ++ +++ +M F S ++Q I DY+ V LS +NGV ++Q+ G +A Sbjct: 125 QGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA-QYA 183 Query: 184 LRIWPNPVKLGQYNLTTADLITVLQQNNYQSAVGQFNSSLTI------LNGTINTQVDTV 237 +RIW + L +Y LT D+I L+ N Q A GQ + + + T+ Sbjct: 184 MRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKNP 243 Query: 238 DGLKKLVIKSD-SGQVVQLQDVADISLGKSSDSTRALANGREAVIIGINATPTANPLDVA 296 + K+ ++ + G VV+L+DVA + LG + + A NG+ A +GI AN LD A Sbjct: 244 EEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDTA 303 Query: 297 EGIRTKFDLVEKNLPTTIQSTLIYDSTLAITDSIDEVVKTIAEAAVIVIVVILLFLGSFR 356 + I+ K ++ P ++ YD+T + SI EVVKT+ EA ++V +V+ LFL + R Sbjct: 304 KAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMR 363 Query: 357 AVIIPIITIPLSLIGVIAVMQVFGFSLNLMTLLAMVLAIGLVVDDAIVVVENVDRHIKM- 415 A +IP I +P+ L+G A++ FG+S+N +T+ MVLAIGL+VDDAIVVVENV+R + Sbjct: 364 ATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMMED 423 Query: 416 GTKPLEAALVATREIAVPIISMTITLAAVYAPIALMGGVTGSLFKEFALTLAGSVVISGF 475 P EA + +I ++ + + L+AV+ P+A GG TG+++++F++T+ ++ +S Sbjct: 424 KLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVL 483 Query: 476 VALTLSPMMCSKMLKP-----HAQPSKFEETVERVLGGLTSRYHKTLLAVLDHRGAMVFF 530 VAL L+P +C+ +LKP H F + Y ++ +L G + Sbjct: 484 VALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLLI 543 Query: 531 AVIVFVSLPIIFSFIPSQLAPDEDQGVVVVIGTTPSTSNNDYIQANMELITQIISKQPQ- 589 ++ + ++F +PS P+EDQGV + + P+ + + Q ++ +T K + Sbjct: 544 YALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNEKA 603 Query: 590 -VEASLALIGV----PTSSQGLAIAPLVPWSDR---ALSQKQISANVNKQAKKIPGITAT 641 VE+ + G + G+A L PW +R S + + + KI Sbjct: 604 NVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGFVI 663 Query: 642 AYQMP--SLPGASGGLPIQFVITSPASFETLYNIGNKLLEKAKKSPL-LVYTDLNLKYDS 698 + MP G + G + + + + L N+LL A + P LV N D+ Sbjct: 664 PFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLEDT 723 Query: 699 GLVQLKIDREAAGAYGVTMQEIGSTLGTMMGGGYINRVNIDGRSYEVIPQVERVYRANPK 758 +L++D+E A A GV++ +I T+ T +GG Y+N GR ++ Q + +R P+ Sbjct: 724 AQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRMLPE 783 Query: 759 LIDQFYVTAQNGTAIPLSSLVSYSVNGNAKSLPHFNQMNSISIEAVPAPNVAMGDAIAYF 818 +D+ YV + NG +P S+ + + L +N + S+ I+ AP + GDA+A Sbjct: 784 DVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMALM 843 Query: 819 EQLAKTDLPPGFTYTFMGEARQFVEEGSSLYVTFALALAIIFLVLASQFESVRDPLVIMF 878 E L + LP G Y + G + Q G+ A++ ++FL LA+ +ES P+ +M Sbjct: 844 ENL-ASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVML 902 Query: 879 TVPLAISGALIALGWTHVSGETSLNIYSQVGLITLVGLITKHGILMCEVAKEEQIFKGAT 938 VPL I G L+A + ++Y VGL+T +GL K+ IL+ E AK+ +G Sbjct: 903 VVPLGIVGVLLAATLFN----QKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKG 958 Query: 939 KHDAIIEAATVRLRPILMTTSAMIAGLIPLLFASGAGAASRYNIGLVIVAGLAVGTAFTL 998 +A + A +RLRPILMT+ A I G++PL ++GAG+ ++ +G+ ++ G+ T + Sbjct: 959 VVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAI 1018 Query: 999 FVLPVMYTYI 1008 F +PV + I Sbjct: 1019 FFVPVFFVVI 1028
>RTXTOXINC#Gram-negative bacterial RTX toxin-activating protein C signature. Length = 170 Score = 30.2 bits (68), Expect = 0.006 Identities = 15/60 (25%), Positives = 26/60 (43%), Gaps = 2/60 (3%) Query: 3 FPSRLLLLLEVAELGSFSKVAEQR--NVDRSVISKQINRLEHELGVHLLNRTTRSLSLTA 60 FP L + V KV+E +D+ + +K + HEL + ++ + SLT Sbjct: 111 FPDELFRAIRVDPKTHVGKVSEFHGGKIDKQLANKIFKQYHHELITEVKRKSDFNFSLTG 170
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 24.8 bits (54), Expect = 0.022 Identities = 10/44 (22%), Positives = 20/44 (45%) Query: 9 AIESPFDGVVGAFFFEPGELVSDGMLLAEVEAKVETAELEPTET 52 I+ + +V + GE V G +L ++ A A+ T++ Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQS 141
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 996 bits (2576), Expect = 0.0 Identities = 474/1033 (45%), Positives = 676/1033 (65%), Gaps = 7/1033 (0%) Query: 1 MSYFFISRPVFAWVIAILISIAGVIAIPKLAVERFPSVAPPSIGLYLSYPGASPQTINDS 60 M+ FFI RP+FAWV+AI++ +AG +AI +L V ++P++APP++ + +YPGA QT+ D+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VVTLIEREISGINGLLYFSSSSDASGSASITVTFENGTDPEMAQVEIQNKIRAIEPRLPL 120 V +IE+ ++GI+ L+Y SS+SD++GS +IT+TF++GTDP++AQV++QNK++ P LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 AVRQIGITVETTSSNNLMYLGLISPSGEYSEQQLSDYMVRNIVEEIKRVPGVGRVQMYGA 180 V+Q GI+VE +SS+ LM G +S + ++ +SDY+ N+ + + R+ GVG VQ++GA Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 EFAMRIWVDPVALTGYNLTMEDVTSAIAEQNVQISPGKVGDSPTSGGQMTVHSLTAQGQL 240 ++AMRIW+D L Y LT DV + + QN QI+ G++G +P GQ S+ AQ + Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 ETPEQFRAIVLRSNIDAGMVQLGDVAKVELGAQNYLFSNRENGQQSTSAAIQLSPGANAI 300 + PE+F + LR N D +V+L DVA+VELG +NY R NG+ + I+L+ GANA+ Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 ATSQGIRDRLAELKLAMPSNMDYSITSDAAIFAKISIQKVVVTLLEAMVLVFLVMYLFLQ 360 T++ I+ +LAEL+ P M D F ++SI +VV TL EA++LVFLVMYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 KIRYTLIPAIVAPIALLGTFAVMWLMGFSINVFTMFGMVLAIGIIVDDAIVVVENVERVM 420 +R TLIP I P+ LLGTFA++ G+SIN TMFGMVLAIG++VDDAIVVVENVERVM Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 AETGLPPKAATEQAMKSIYSAVIGITAVLSAVFIPMAFASGSVGTIFQQFSLAMAVSILF 480 E LPPK ATE++M I A++GI VLSAVFIPMAF GS G I++QFS+ + ++ Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SAFLALTLTPALCATLLKPLTEHDHKS-GGFFGWFNRNFHNFTQKVTAGVAHLVKRTGRV 539 S +AL LTPALCATLLKP++ H++ GGFFGWFN F + T V ++ TGR Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 Query: 540 MALYIVLVVACIYSFTLVPSTFLPEEDQGYYMTSIQLPPDATVERTMDVVSKIEAFTLGR 599 + +Y ++V + F +PS+FLPEEDQG ++T IQLP AT ERT V+ ++ + L Sbjct: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 Query: 600 EA--IDASMSVLGFSFSGTGPGSAFGITTLKDWQLRGG--SSTQQEVAALSDYLSDLTEG 655 E +++ +V GFSFSG + +LK W+ R G +S + + L + +G Sbjct: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG 660 Query: 656 EVFSVLPAAIDGLGNSSNLSFQLQDSGNAGYERFQLIQKEFLEQA-YASEKLSSVFYEAL 714 V AI LG ++ F+L D G++ + + L A L SV L Sbjct: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 Query: 715 PETSGIHLNIDRAKARALGVPFNAISDTISTAMGSNYVNDFPNNGRLQQVIVQVQAESRM 774 +T+ L +D+ KA+ALGV + I+ TISTA+G YVNDF + GR++++ VQ A+ RM Sbjct: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM 780 Query: 775 QLEDILQLAIRNEQGGTVYLSEFVTPVWQMAPQQLTRFNGLLAVAVSASPAPGYSTGEAM 834 ED+ +L +R+ G V S F T W +L R+NGL ++ + APG S+G+AM Sbjct: 781 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM 840 Query: 835 QEVERIAASLPTAAGIEWTGLSLQEKQAESQTVWLLLFSMLVIFLVLAALYESWSIPLAV 894 +E +A+ LP G +WTG+S QE+ + +Q L+ S +V+FL LAALYESWSIP++V Sbjct: 841 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900 Query: 895 ILVVPLGIIGAVGFVLLNGVANDVFFKVGLVTIIGLSAKNAILIVEFAKQAQ-AEGICLV 953 +LVVPLGI+G + L NDV+F VGL+T IGLSAKNAILIVEFAK EG +V Sbjct: 901 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV 960 Query: 954 DSVLQATKQRLRPILMTSLAFSCGIIPLYLATGPSSEIQNSIGTGVLGGMFTGTVFAVLF 1013 ++ L A + RLRPILMTSLAF G++PL ++ G S QN++G GV+GGM + T+ A+ F Sbjct: 961 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF 1020 Query: 1014 VPVFFVFICQLLE 1026 VPVFFV I + + Sbjct: 1021 VPVFFVVIRRCFK 1033 Score = 86.4 bits (214), Expect = 3e-19 Identities = 48/326 (14%), Positives = 121/326 (37%), Gaps = 17/326 (5%) Query: 720 IHLNIDRAKARALGVPFNAISDTISTA---MGSNYVNDFPNNGRLQQVIVQVQAESRMQ- 775 + + +D + + + + + + + P QQ+ + A++R + Sbjct: 184 MRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPG-QQLNASIIAQTRFKN 242 Query: 776 LEDILQLAIR-NEQGGTVYLSEFVTPVWQMAPQQ-LTRFNGLLAVAVSASPAPGYSTGEA 833 E+ ++ +R N G V L + + R NG A + A G + + Sbjct: 243 PEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDT 302 Query: 834 ----MQEVERIAASLPTAAGIEWTGLSLQE---KQAESQTVWLLLFSMLVIFLVLAALYE 886 ++ + P G++ + + + V L +++++FLV+ + Sbjct: 303 AKAIKAKLAELQPFFP--QGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 887 SWSIPLAVILVVPLGIIGAVGFVLLNGVANDVFFKVGLVTIIGLSAKNAILIVE-FAKQA 945 + L + VP+ ++G + G + + G+V IGL +AI++VE + Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 946 QAEGICLVDSVLQATKQRLRPILMTSLAFSCGIIPLYLATGPSSEIQNSIGTGVLGGMFT 1005 + + ++ ++ Q ++ ++ S IP+ G + I ++ M Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 1006 GTVFAVLFVPVFFVFICQLLERVRPK 1031 + A++ P + + + + Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHE 506
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 42.1 bits (99), Expect = 3e-06 Identities = 30/158 (18%), Positives = 60/158 (37%), Gaps = 8/158 (5%) Query: 58 QGRVRPL-RSAEIRPQVEGIITQRLFKQGDTLKQGDALFQIDQDIFTIDVEIKQAALEQS 116 G++ RS EI+P I+ + + K+G+++++GD L ++ D Q++L Q+ Sbjct: 87 NGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQA 146 Query: 117 MAHLALIQS-----QVDRFTQLDRTKAVSKQAFEEVSFNLQIAAATVQQNRAQLKHSELQ 171 Q ++++ +L Q E + Q + Q + + + Sbjct: 147 RLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKE 206 Query: 172 LEYAKVTAPISGIIGEALVTEGSLVSRTEPQPLAIIQQ 209 L K A + A + +SR E L Sbjct: 207 LNLDKKRAERLTV--LARINRYENLSRVEKSRLDDFSS 242 Score = 37.1 bits (86), Expect = 1e-04 Identities = 43/273 (15%), Positives = 91/273 (33%), Gaps = 41/273 (15%) Query: 39 ANIATITAELTQVTLFDELQGRVRPLRSAEIRPQVEGIITQRLFKQGDTLKQGDALFQID 98 N+ AE + R+ + + L + K A+ + + Sbjct: 207 LNLDKKRAER------LTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKH--AVLEQE 258 Query: 99 QDIFTIDVEIKQAALEQSMAHLALIQSQVDRFTQLDRTKAVSKQAFEEVSFNLQIAAATV 158 L + L I+S++ + + V++ E+ L+ + Sbjct: 259 NKYVEA-----VNELRVYKSQLEQIESEILSAKE--EYQLVTQLFKNEILDKLRQTTDNI 311 Query: 159 QQNRAQLKHSELQLEYAKVTAPISGIIGEALV-TEGSLVSRTEPQPLAIIQQIDKVYIDV 217 +L +E + + + + AP+S + + V TEG +V+ E + I+ + D + + Sbjct: 312 GLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETL-MVIVPEDDTLEVTA 370 Query: 218 RQPASKLGLLRRLLANEQKNSEQGVKVIVQSSA---ESADDIEGQI--LFSGISVDENTG 272 +G + G I++ A + G++ + D+ G Sbjct: 371 LVQNKDIGFIN-----------VGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLG 419 Query: 273 ---DLIIRI-----IADNAQQKLLPGMYVRTQI 297 ++II I N L GM V +I Sbjct: 420 LVFNVIISIEENCLSTGNKNIPLSSGMAVTAEI 452
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 85.3 bits (211), Expect = 2e-21 Identities = 34/135 (25%), Positives = 60/135 (44%), Gaps = 1/135 (0%) Query: 2 IRVLLIEDDRDLAETLLQLMELAQMLPDHVSNGIAGLTLARSNSYDVLVIDVGLPKLDGY 61 +L+ +DD + L Q + A SN + D++V DV +P + + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 SVCKQLRASGIDTPILFLTAFSSIDNKLEGFASGGDDYLAKPFDNRELIARI-TALSGRK 120 + +++ + D P+L ++A ++ ++ G DYL KPFD ELI I AL+ K Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 121 SSHVKRLEIAGLIMN 135 K + + M Sbjct: 124 RRPSKLEDDSQDGMP 138
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 48.3 bits (115), Expect = 9e-10 Identities = 13/55 (23%), Positives = 36/55 (65%) Query: 23 KDEGFTLIELVVVIIILGIVSVIAIPKFISFEDESRDAVMRQTLASVKSAISLVR 77 K GFTL+E++VVI+I+G+++ + +P + ++++ + ++++A+ + + Sbjct: 6 KQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK 60
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 181 bits (460), Expect = 1e-53 Identities = 51/279 (18%), Positives = 106/279 (37%), Gaps = 44/279 (15%) Query: 39 ESVLNQNHACSDTI-IIRSQA-LTKEQISSACELLVRQEANFHQLFGTLNKPVADDNNHS 96 E L + + D ++++ +T+E+I +A F ++ + + Sbjct: 387 EKYLPKTYTFDDGKFVVKAGDKVTEEKIKRLYWASKEVKAQFMRVVQNDKALEEGNPDDI 446 Query: 97 MRANVYHSREDYVAHVTNHFDVPSDNGGMYLEGLPWKSDNQAEFVAYEKKGQ-----VWN 151 + +Y+S E+Y + +DNGG+Y+E N F YE+ + + Sbjct: 447 LTVVIYNSPEEYKLNRI-INGFSTDNGGIYIE-------NIGTFFTYERTPEESIYTLEE 498 Query: 152 LA-HEYVHYLDGRFNLYGDFCLSLHDSHSGPEYCPKPAPLYPHTVWWSEGVAEYISLGEN 210 L HE+ HYL GR+ + G + W+ EG AE+ + Sbjct: 499 LFRHEFTHYLQGRYVVPGMWGQGEFYQEG-------------VLTWYEEGTAEFFAGSTR 545 Query: 211 NP---------KAFALIGEKNLELSDIFNTSYEQNGGTDRVYRWGYLAVRFMIENHKDKV 261 + A + L + + Y G+ Y +G+ +M N+ Sbjct: 546 TDGIKPRKSVTQGLAYDRNNRMSLYGVLHAKY----GSWDFYNYGFALSNYMYNNNMGMF 601 Query: 262 DEMLSFTRKGDYPRYQALIKQWGN--SMDDEFQIWLKTL 298 ++M ++ + D Y+ I + ++D++Q ++ +L Sbjct: 602 NKMTNYIKNNDVSGYKDYIASMSSDYGLNDKYQDYMDSL 640 Score = 80.5 bits (198), Expect = 5e-19 Identities = 25/167 (14%), Positives = 50/167 (29%), Gaps = 40/167 (23%) Query: 147 GQVWNLAHEYVHYLDGRFNLYGDFCLSLHDSHSGPEYCPKPAPLYPHTVWWSEGVAEYIS 206 + L +Y Y+D N + + L + + A+ I+ Sbjct: 624 SSDYGLNDKYQDYMDSLLNNIDNLDVPLVSD-----------------EYVNGHEAKDIN 666 Query: 207 LGENNPKAFALIGEKNLE-LSDIFNTSYEQNGGTDRVYRWGYLAVRFMIENH-----KDK 260 N+ K + I + + F T+Y+ R Y+ R E + K Sbjct: 667 EITNDIKEVSNIKDLSSNVEKSQFFTTYD--------MRGTYVGGRSQGEENDWKDMNSK 718 Query: 261 VDEMLSFTRKGDYPRYQALIKQWGNSMDD---------EFQIWLKTL 298 ++++L K + Y+ + + N D F Sbjct: 719 LNDILKELSKKSWNGYKTVTAYFVNHKVDGNGNYVYDVVFHGMNTDT 765
>PF06580#Sensor histidine kinase Length = 349 Score = 34.8 bits (80), Expect = 5e-04 Identities = 34/196 (17%), Positives = 68/196 (34%), Gaps = 38/196 (19%) Query: 241 NVRAMDQMLQQTTRMRSMVEQLLALSRIEDASDVDLEVKVSMSQMMDILRDEALALAQ-- 298 N+RA+ +L+ T+ R M+ L L R + +VS++ + ++ L LA Sbjct: 181 NIRAL--ILEDPTKAREMLTSLSELMRY--SLRYSNARQVSLADELTVVDS-YLQLASIQ 235 Query: 299 --EQYEVSFYCEPGLDLYGNELLVRSACSNLISNAIRY----TEPGGNIEVSWRKVAIGG 352 ++ + P + + + L+ N I++ GG I + K Sbjct: 236 FEDRLQFENQINPAIM---DVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTV 292 Query: 353 LFSVKDNGEGVAPQHIGRLTERFYRVDSARSRQSGGTGLGLAIAKHALSH---HQSELSI 409 V++ G TG GL + L ++++ + Sbjct: 293 TLEVENTGSLALKN------------------TKESTGTGLQNVRERLQMLYGTEAQIKL 334 Query: 410 MSQLGKGSTFSFVIPA 425 + GK + +IP Sbjct: 335 SEKQGKVNAM-VLIPG 349
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.5 bits (222), Expect = 6e-23 Identities = 30/120 (25%), Positives = 57/120 (47%), Gaps = 2/120 (1%) Query: 3 ARILIVEDELAIREMLTFVLEQHGFTTAAAEDYDSALAMLTEPYPDLVLLDWMFPGGNGI 62 A IL+ +D+ AIR +L L + G+ + + + DLV+ D + P N Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 63 QLAKRLRQDEFTRHIPIIMLTARGEEEDKVRGLEVGADDFMTKPFSPKELVARIKAVMRR 122 L R+++ +P+++++A+ ++ E GA D++ KPF EL+ I + Sbjct: 64 DLLPRIKKAR--PDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 64.1 bits (156), Expect = 9e-14 Identities = 64/331 (19%), Positives = 112/331 (33%), Gaps = 33/331 (9%) Query: 13 AIATATLSSAYAADPLTVYGKLN--VTAQSNDVND-------ESTTTIQSNASRFGVKGA 63 A+ A L A AD +T+YG + V + ++ E+ T I S+ G KG Sbjct: 7 ALTLAALPVAAMAD-VTLYGTIKAGVETSRSVAHNGAQAASVETGTGIVDLGSKIGFKGQ 65 Query: 64 FELSRSLEAFYTIEYEVDTGDDVKENFKARNQFVGLKGNFGAFSVGRNDTMLKVA---QG 120 +L L+A + +E + R F+GLKG FG VGR +++LK Sbjct: 66 EDLGNGLKAIWQVEQKASIAGTDSGWGN-RQSFIGLKGGFGKLRVGRLNSVLKDTGDINP 124 Query: 121 KVDQFNDLSGDLKNLFKGENRIEQTATYVTPSFSGFKVGVTYAAEGAGSQYGQDGFSVAA 180 + + L + + + E R+ + Y +P F+G V YA ++ + + Sbjct: 125 WDSKSDYLGVN--KIAEPEARL-ISVRYDSPEFAGLSGSVQYALNDNAGRHNSESYHAGF 181 Query: 181 IYGDAKLKQSPLYASVAYDADVKGYEVVRATVQGKIAGLKLGGMYQQQEETYDKDGSPTI 240 Y + A + + + + + ++G +Y D Sbjct: 182 NYKNGGFFVQYGGAYKRHHQVQENVNIEKYQIHRLVSGYDNDALYASVAVQQQ-DAKLVE 240 Query: 241 GGESKTG-YLVSAAYQIDAVVLKAQF-------QDMEDKGDS-----WSVGGDYKLGKPT 287 S V+A + + + + VG +Y K T Sbjct: 241 ENYSHNSQTEVAATLAYRFGNVTPRVSYAHGFKGSFDATNYNNDYDQVVVGAEYDFSKRT 300 Query: 288 KLFAFYT-NRSFDNVDN-DDSYFGVGLEHKF 316 + + GVGL HKF Sbjct: 301 SALVSAGWLQEGKGESKFVSTAGGVGLRHKF 331
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 76.0 bits (187), Expect = 3e-16 Identities = 52/202 (25%), Positives = 80/202 (39%), Gaps = 30/202 (14%) Query: 400 IMGHVDHGKTSLLDYI-----RRAKVASGEAG-------------GITQHIGAYHVETEN 441 ++ HVD GKT+L + + ++ S + G GIT G + EN Sbjct: 8 VLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWEN 67 Query: 442 GMITFLDTPGHAAFTAMRARGAKATDIVILVVAADDGVMPQTIEAIQHAKAGGVPLIVAV 501 + +DTPGH F A R D IL+++A DGV QT + G+P I + Sbjct: 68 TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFI 127 Query: 502 NKMDKPEADPDRV----KSELSQHGVMS-------EDWGGNNMFVNVSAKTGAGIDELLE 550 NK+D+ D V K +LS V+ N G D+LLE Sbjct: 128 NKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGNDDLLE 187 Query: 551 GILLEAEVLELKAIKEGMAAGV 572 + + LE +++ + Sbjct: 188 K-YMSGKSLEALELEQEESIRF 208
>SECGEXPORT#Protein-export SecG membrane protein signature. Length = 110 Score = 121 bits (306), Expect = 1e-39 Identities = 66/112 (58%), Positives = 83/112 (74%), Gaps = 3/112 (2%) Query: 1 MYEVLMIIYLMVAIGLVGLILIQQGKGADMGASFGAGASGTLFGSSGSGNFLTRSTAVLA 60 MYE L++++L+VAIGLVGLI++QQGKGADMGASFGAGAS TLFGSSGSGNF+TR TA+LA Sbjct: 1 MYEALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFGSSGSGNFMTRMTALLA 60 Query: 61 VAFFALSLTIGNLSANHTKAEGAWDDLGSDAAQVVEQVQQEA-EKSEDKIPD 111 FF +SL +GN+++N T W++L A EQ Q A K IP+ Sbjct: 61 TLFFIISLVLGNINSNKTNKGSEWENL--SAPAKTEQTQPAAPAKPTSDIPN 110
>adhesinb#Adhesin B signature. Length = 310 Score = 32.5 bits (74), Expect = 0.001 Identities = 18/95 (18%), Positives = 34/95 (35%), Gaps = 16/95 (16%) Query: 142 REARRTFEVIAEELDVVIEKNGTMAFDNAIIAY----EPLWAVGTGKSATPEQAQEVHAF 197 +EA+ F I E +++ G F AY +W + T + TP+Q + + Sbjct: 186 KEAKEKFNNIPGEKKMIVTSEG--CFKYFSKAYNVPSAYIWEINTEEEGTPDQIKTLVEK 243 Query: 198 IRKRLSEVSPFIGENIRILYGGSVTPSNAADLFAQ 232 +RK + L+ S ++ Sbjct: 244 LRKT----------KVPSLFVESSVDDRPMKTVSK 268
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 36.0 bits (83), Expect = 4e-04 Identities = 23/82 (28%), Positives = 32/82 (39%), Gaps = 18/82 (21%) Query: 193 VLLVGPPGTGKTLLAKAIAGESK---VPFFT-----ISGSDFVEMFVGV------GASRV 238 +++ G GTGK L+A+A+ K PF I G GA Sbjct: 163 LMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTR 222 Query: 239 RD-MFEQAKKSAPCIIFIDEID 259 FEQA+ +F+DEI Sbjct: 223 STGRFEQAEGGT---LFLDEIG 241
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 240 bits (614), Expect = 3e-80 Identities = 89/302 (29%), Positives = 155/302 (51%), Gaps = 18/302 (5%) Query: 14 KARYLSSIFSVLIMLSSIGIILVNGFNWGLDFTGGIVTEVKLDPKIKSAQISELLAETSE 73 + ++ + ++++M++S+ + LV G N+G+DF GG + I L Sbjct: 18 RWQWATFGAAIVMMIASVILPLVIGLNFGIDFKGGTTIRTESTTAIDVGVYRAALEPLEL 77 Query: 74 QEVSV------------------ISAGEPGRWILRYAKVDNAGAHDIKTVLAPLTDNVEV 115 +V + I E G+ + ++T L + +++ Sbjct: 78 GDVIISEVRDPSFREDQHVAMIRIQMQEDGQGAEGQGAQGQELVNKVETALTAVDPALKI 137 Query: 116 LNSSIVGPQIGQELAEQGGLALLAAMLCILAYLSFRFEWRLASGALLALFHDVIFVLAFF 175 + VGP++ EL +LLAA + I+ Y+ RFEW+ A GA++AL HDV+ + F Sbjct: 138 TSFESVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGAVVALVHDVLLTVGLF 197 Query: 176 SLTQMEFNLTILAAVLAILGYSLNDSIVIADRVREVLIAKPKMAIDEICSSAVQATFSRT 235 ++ Q++F+LT +AA+L I GYS+ND++V+ DR+RE LI M + ++ + +V T SRT Sbjct: 198 AVLQLKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRDVMNLSVNETLSRT 257 Query: 236 MVTSGTTLFTVAALWIMGGAPLQGFSIAMFLGIMIGTISSVSVGTCLPEYLKVSAEHYKV 295 ++T TTL + + I GG ++GF AM G+ GT SSV V + ++ + K Sbjct: 258 VMTGMTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAKNIVLFIGLDRNKEKK 317 Query: 296 EP 297 +P Sbjct: 318 DP 319
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 83.0 bits (205), Expect = 2e-19 Identities = 40/214 (18%), Positives = 94/214 (43%), Gaps = 5/214 (2%) Query: 383 SVATIQAQLGDRFSITGSADYASAQQLALLLRAGSMTAP-VTIVEERTIGPSLGEENITN 441 VA I+ Q+ + + + + A + P + I ++GP + E + Sbjct: 95 HVAMIRIQMQEDGQGAEGQGAQGQELVNKVETALTAVDPALKITSFESVGPKVSGELVWT 154 Query: 442 GFSALALGMAVTLLFMGLWYR-RLGWIANVALIANMILIFGLMALIPGAVLTLPGIAGLV 500 +L V + ++ + + + A VAL+ +++L GL A++ L +A L+ Sbjct: 155 AVWSLLAATVVIMFYIWVRFEWQFALGAVVALVHDVLLTVGLFAVL-QLKFDLTTVAALL 213 Query: 501 LTVGMAVDTNVLIFERIKDKLK--EGRSFAHAIDRGFDSAFSTIVDANFTTMITAVVLYA 558 G +++ V++F+R+++ L + ++ + S V TT++ V + Sbjct: 214 TITGYSINDTVVVFDRLRENLIKYKTMPLRDVMNLSVNETLSRTVMTGMTTLLALVPMLI 273 Query: 559 IGNGPIQGFALTLGLGLLTSMFTGIFASRALVNW 592 G I+GF + G+ T ++ ++ ++ +V + Sbjct: 274 WGGDVIRGFVFAMVWGVFTGTYSSVYVAKNIVLF 307
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 28.3 bits (63), Expect = 0.006 Identities = 12/32 (37%), Positives = 21/32 (65%) Query: 8 MKKQLAVIALVSLSVVGCSSSNYEKEQTSAPY 39 MK +L+ +AL + +VGC+SS +++ S P Sbjct: 1 MKLRLSALALGTTLLVGCASSGTDQQGRSDPL 32
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 40.6 bits (95), Expect = 2e-05 Identities = 37/168 (22%), Positives = 62/168 (36%), Gaps = 30/168 (17%) Query: 570 VIGQNEAVNSVSNAIRRSRAGLSDPDRPIGSFLFLGPTGVGKTELCKALAKFLFDTESAL 629 ++G++ A+ + + R L D + + G +G GK + +AL + Sbjct: 139 LVGRSAAMQEIYRVLAR----LMQTDLTL---MITGESGTGKELVARALHDYGKRRNGPF 191 Query: 630 VRIDMSEFMEKHSVSRLVGAPPGYVGYEEGGYLTEAVRRKPYSV-------ILLDEVEKA 682 V I+M+ S L G +E+G + T A R + LDE+ Sbjct: 192 VAINMAAIPRDLIESELFG-------HEKGAF-TGAQTRSTGRFEQAEGGTLFLDEIGDM 243 Query: 683 HPDVFNILLQVLDDG---RLTDGQGRTVDFRNTVVIMTSNLGSDLIQM 727 D LL+VL G + D R ++ +N DL Q Sbjct: 244 PMDAQTRLLRVLQQGEYTTVGGRTPIRSDVR---IVAATN--KDLKQS 286 Score = 31.7 bits (72), Expect = 0.015 Identities = 17/88 (19%), Positives = 37/88 (42%), Gaps = 4/88 (4%) Query: 131 ATKELMESTIDQIRNGQNVDDPNAEDQRQALKKFTVDLTERAEQG-KLDPVIGRDDEIRR 189 A K + D + ++ + +AL + ++ + P++GR ++ Sbjct: 90 AIKASEKGAYDYLPKPFDLTE-LIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQE 148 Query: 190 TIQVLQRRSKNN-PVLI-GEPGVGKTAI 215 +VL R + + ++I GE G GK + Sbjct: 149 IYRVLARLMQTDLTLMITGESGTGKELV 176
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 32.9 bits (75), Expect = 0.005 Identities = 24/141 (17%), Positives = 55/141 (39%), Gaps = 10/141 (7%) Query: 196 IIFLMAALF---IRQALWIFAICINSGIALVLSMGLAAWLKLTLAAITAFVPVIIVTLGL 252 ++FL+ LF +R L I I + + L+ + + A ++ +T F V+ + L + Sbjct: 350 LVFLVMYLFLQNMRATL-IPTIAVP--VVLLGTFAILAAFGYSINTLTMFGMVLAIGLLV 406 Query: 253 AYASHLYFG-WRAEINRGQTHQQALRYTVKVNQAPLFYSTITTIFGFSLLMFSPSPP--- 308 A + R + ++A ++ Q L + F + F Sbjct: 407 DDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAI 466 Query: 309 IQSFGLLVAFAVLCNYVLSLT 329 + F + + A+ + +++L Sbjct: 467 YRQFSITIVSAMALSVLVALI 487 Score = 31.0 bits (70), Expect = 0.023 Identities = 25/170 (14%), Positives = 61/170 (35%), Gaps = 17/170 (10%) Query: 144 LDDVLQKVDRDSREYWLPLGVNTYFNGTHALNWQYAKVLGHDLSW-FAPALLGIIFLMAA 202 D + ++ + LP G+ + G ++ G+ A + + + +AA Sbjct: 836 SGDAMALMENLAS--KLPAGIGYDWTGMS----YQERLSGNQAPALVAISFVVVFLCLAA 889 Query: 203 LF--IRQALWIFAICINSGIALVLSMGLAAWLKLTLAAITAFVPVIIVTLGLAYASHLY- 259 L+ + + + + ++L+ L K + + + T+GL+ + + Sbjct: 890 LYESWSIPVSVMLVVPLGIVGVLLAATLFN-QKNDVYFMVGL----LTTIGLSAKNAILI 944 Query: 260 --FGWRAEINRGQTHQQALRYTVKVNQAPLFYSTITTIFGFSLLMFSPSP 307 F G+ +A V++ P+ +++ I G L S Sbjct: 945 VEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGA 994
>BONTOXILYSIN#Bontoxilysin signature. Length = 1196 Score = 30.3 bits (68), Expect = 0.026 Identities = 11/87 (12%), Positives = 34/87 (39%) Query: 182 NNLEAFINTANVSQLDGQAKQQVLNYIQQYNADFKALVDKEKQLGLTISEGERGQLRQAV 241 N ++ F+N A++ + ++Y+++Y + + Q I++ E+ L + Sbjct: 742 NRVDNFLNKASICVFVEDIYPKFISYMEKYINNINIKTREFIQRCTNINDNEKSILINSY 801 Query: 242 ANTDSALNQLESLALDAISDKESSAFI 268 L+ ++ + + + Sbjct: 802 TFKTIDFKFLDIQSIKNFFNSQVEQVM 828
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 74.2 bits (182), Expect = 3e-18 Identities = 34/195 (17%), Positives = 67/195 (34%), Gaps = 9/195 (4%) Query: 43 AVSISIAMQASQANKAVEQIKPALEKQTKPSPRPLAKPLPESAATPVVKAKPITEPELAT 102 A IS+ M A + + ++P E +P P P P P A V++ Sbjct: 47 AQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPK 106 Query: 103 QPKPAPSQDTEKPIAEINEIQVAHNQIQVDAKQGVTQQSITLSQPTFAAPP-----AQPH 157 K + E N + + + A+ P QP Sbjct: 107 PVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQ 166 Query: 158 YPKKARKRGFQGTATVEVMFNQLGEQLSLTLVGSSGYRLLDKAALNAVEQWQFAAPTPQT 217 YP +A+ +G V+ G ++ ++ + + ++ NA+ +W++ P + Sbjct: 167 YPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGS 226 Query: 218 AYAYTVRVPVKFALN 232 + V + F +N Sbjct: 227 ----GIVVNILFKIN 237
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 44.6 bits (105), Expect = 2e-07 Identities = 62/299 (20%), Positives = 114/299 (38%), Gaps = 40/299 (13%) Query: 9 LVNNKMSISAALLSVLV--INQPVLAHQDKAHSETARVVSAGAGVTELVLAL-------- 58 L++ + ++A LS L+ +N A D R+V+ EL+LAL Sbjct: 6 LISRRRLLTAMALSPLLWQMNTAHAAAID-----PNRIVALEWLPVELLLALGIVPYGVA 60 Query: 59 DAGNELVAVDSTSQLPEEYTNIEKLGYHRMLSAEGILALSPDLLLGSDAMGPQTTLDVLT 118 D N + V LP+ ++ G + E + + P ++ S GP + ++L Sbjct: 61 DTINYRLWVSEPP-LPDSVIDV---GLRTEPNLELLTEMKPSFMVWSAGYGP--SPEML- 113 Query: 119 AAKVKVVQLATANSQSQLI---NNISEMGKLLNREAQAKKLQAEIKQSFKNIEQKQQKIA 175 A ++ + L +++EM LLN ++ A+ A+ + + + Sbjct: 114 ARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAQYEDFI---RSMKPRFV 170 Query: 176 KQGEAPKVLFLLLQTDRPARVGGDDTAADIIIKLAGGKNI----AGFSGYKSVSQEGILS 231 K+G P +L L+ R V G ++ I+ G N F G +VS + + + Sbjct: 171 KRGARPLLLTTLIDP-RHMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAA 229 Query: 232 LQ-PDVILISNRSNKAVQNPVDALLNNMPLLAHTPAGKNKQIQFLQPQALLGGLGLSAI 289 + DV+ + L PL P + + Q + G LSA+ Sbjct: 230 YKDVDVLCFD-----HDNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGAT-LSAM 282
>TETREPRESSOR#Tetracycline repressor protein signature. Length = 218 Score = 48.4 bits (115), Expect = 2e-09 Identities = 27/92 (29%), Positives = 50/92 (54%), Gaps = 4/92 (4%) Query: 16 SQLSKEAIVIQAKALMLSDG-KIPSIRHLAGKLSVDAMAIYHYFKNKDALLEAITTSLVS 74 ++L++E+++ A L+ G + R LA KL ++ +Y + KNK ALL+A+ +++ Sbjct: 2 ARLNRESVIDAALELLNETGIDGLTTRKLAQKLGIEQPTLYWHVKNKRALLDALAVEILA 61 Query: 75 E---ICQPEAGDKWQQALTELSLSYLNLLKQY 103 P AG+ WQ L ++S+ L +Y Sbjct: 62 RHHDYSLPAAGESWQSFLRNNAMSFRRALLRY 93
>PF01540#Adhesin lipoprotein Length = 475 Score = 27.4 bits (60), Expect = 0.042 Identities = 11/46 (23%), Positives = 23/46 (50%), Gaps = 4/46 (8%) Query: 75 NKPVFVLSNTLTEVPAELEGKAFIING----ELEHIVQQLNSKGYQ 116 ++ + ++T+ +LEGK F I+ +L ++ LN K + Sbjct: 134 SEKIQSFADTIALTITKLEGKKFQIDETFKKQLISTIELLNKKSAE 179
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 26.3 bits (58), Expect = 0.028 Identities = 9/20 (45%), Positives = 11/20 (55%) Query: 30 DFSKTVAARADYDFSKNISA 49 + V A+YDFSK SA Sbjct: 283 NDYDQVVVGAEYDFSKRTSA 302
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 73.7 bits (181), Expect = 2e-15 Identities = 29/112 (25%), Positives = 47/112 (41%), Gaps = 2/112 (1%) Query: 1077 DSGYVLLVEDNFINQQVATELLKSAGYTVDVAENGQIALDMIDKTQYDAVLMDIQMPVMD 1136 +L+ +D+ + V + L AGY V + N I D V+ D+ MP + Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 1137 GLTATKELRKRYSTEELPVIAMTAHAMSGDREKSLAAGMNAHITKPIVLTEL 1188 ++K +LPV+ M+A K+ G ++ KP LTEL Sbjct: 62 AFDLLPRIKKAR--PDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTEL 111 Score = 64.5 bits (157), Expect = 1e-12 Identities = 20/108 (18%), Positives = 42/108 (38%), Gaps = 6/108 (5%) Query: 937 KTLVIDDNPTALQIYSSVLRDFHFNVDTAASGPEGLYKLGKNPVDLLLLDWMMPEMDGIE 996 LV DD+ + + L ++V ++ + DL++ D +MP+ + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 997 VIKQIDAMVADGRLEKRPIIIMMTAYTAEPMHKDVEQANVYALLQKPF 1044 ++ +I P+++ M+A + Y L KPF Sbjct: 65 LLPRIKK-----ARPDLPVLV-MSAQNTFMTAIKASEKGAYDYLPKPF 106
>FRAGILYSIN#Fragilysin metallopeptidase (M10C) enterotoxin signature. Length = 405 Score = 30.4 bits (68), Expect = 0.017 Identities = 15/68 (22%), Positives = 26/68 (38%) Query: 373 LVKEMGTGLIVTEVMGQGVNTVTGDYSRGAAGFYVENGVILYPVEEITIAGNLKDMYQNI 432 ++E G+ + EV Q + Y+ YV +LY E +G+ K+ + Sbjct: 232 CLRENGSTIYPNEVSAQMQDAANSVYAVHGLKRYVNFHFVLYTTEYSCPSGDAKEGLEGF 291 Query: 433 VAVAKDRD 440 A K Sbjct: 292 TASLKSNP 299
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 30.3 bits (68), Expect = 0.005 Identities = 17/121 (14%), Positives = 36/121 (29%), Gaps = 14/121 (11%) Query: 44 SKTQVEKLNLDETLHDNVLKAKTIKMNTEAHRRHIQYIGKL--------------MRYVD 89 SK+ + + + D A + + +R I I +L ++Y Sbjct: 219 SKSALPGSMVANVVADERTNAVLVSGEPNSRQRIIAMIKQLDRQQATQGNTKVIYLKYAK 278 Query: 90 LEELEVAIRNVLNKNSNESAKTNVADKTRDQLLAEGDSAVQALIEQHPEFDRQKLRQFIR 149 +L + + + +E ++ + ALI L + I Sbjct: 279 ASDLVEVLTGISSTMQSEKQAAKPVAALDKNIIIKAHGQTNALIVTAAPDVMNDLERVIA 338 Query: 150 Q 150 Q Sbjct: 339 Q 339
>INTIMIN#Intimin signature. Length = 939 Score = 34.3 bits (78), Expect = 0.003 Identities = 46/239 (19%), Positives = 95/239 (39%), Gaps = 34/239 (14%) Query: 278 NKLATTLPFEADKYIVSAGGTFGVTADLATKNDDGSYTRLQTPTSVSFNSSCISSNNASI 337 N + T+ ++ +V G TAD + DG+ + + A++ Sbjct: 540 NNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGT-----EAITYTATVKKNGVAQANV 594 Query: 338 DSPVTTLSGTASSTFQNTNCSGNGE--------RDDQIIASVVAGNQTLTAELNFS-LAS 388 +SGTA + + N +G+G+ + Q++ S T N Sbjct: 595 PVSFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFVD 654 Query: 389 QTLANLSFISAEPTSIRIKGAGGTGSSESSLITFKV-SDANGQAIAQQAVDFSLDTTVGG 447 QT A+++ I A+ T+ ++ IT+ V + ++ Q V F TT+G Sbjct: 655 QTKASITEIKADKTTAV--------ANGQDAITYTVKVMKGDKPVSNQEVTF--TTTLGK 704 Query: 448 ISFANGGTSTSNTSNSAGLVSATVLSGTMPTPVRVLATATANGESVTTQSEQLTINTGL 506 + ++++ +++ G T+ S TP + L +A + +V ++ ++ T L Sbjct: 705 L------SNSTEKTDTNGYAKVTLTST---TPGKSLVSARVSDVAVDVKAPEVEFFTTL 754 Score = 33.1 bits (75), Expect = 0.006 Identities = 32/148 (21%), Positives = 62/148 (41%), Gaps = 11/148 (7%) Query: 82 SGQLISFSTSFGELSVATKLTNSNGLAEIIVSNPTAAEGAGTLTASFTEGENNANASKNF 141 S Q ++F+T+ G+LS +T+ T++NG A++ +++ T G ++A + + Sbjct: 692 SNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTP--GKSLVSARVS-DVAVDVKAPEV 748 Query: 142 EFTSATAPSEPKFSLNSAIINGTTVVTQFKAGETVQLQAQFLDEQGQGVAGKKASFTAGS 201 EF + + + + G + G V L+A G S Sbjct: 749 EFFTTLTIDDGNIEIVGTGVKGKLPTVWLQYG-QVNLKA-----SGGNGKYTWRSANPAI 802 Query: 202 ASLNPDSALT--KDNGIAQVSYTPSDSE 227 AS++ S K+ G +S SD++ Sbjct: 803 ASVDASSGQVTLKEKGTTTISVISSDNQ 830
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 42.5 bits (100), Expect = 1e-06 Identities = 32/176 (18%), Positives = 62/176 (35%), Gaps = 12/176 (6%) Query: 2 RTNRILAAVALIVLIGALLYGLLLAYTPKPQLLQGQI--EAREYNVSSKVPGRVEEVLVR 59 R R++A + L+ A + +L G++ R + V+E++V+ Sbjct: 55 RRPRLVAYFIMGFLVIAFILSVL-GQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVK 113 Query: 60 RGDLVTEGDLLFAINSPELEAKLMQAEGGRDAAVAMQKEADNGARKQQIAAAKEEWLKAQ 119 G+ V +GD+L + + EA ++ + A ++ + I K LK Sbjct: 114 EGESVRKGDVLLKLTALGAEADTLKTQ--SSLLQARLEQTRYQILSRSIELNKLPELKLP 171 Query: 120 AAAKLYRTTYERLEVLFNEGVLARQKRDEAFTQWQAAKYTEQAALAMYQMTDEGAR 175 + E E + E F+ WQ KY ++ L + Sbjct: 172 DEPYFQNVSEE-------EVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVL 220
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 551 bits (1422), Expect = 0.0 Identities = 310/348 (89%), Positives = 330/348 (94%), Gaps = 1/348 (0%) Query: 1 MFKKLRGIFSNDLSIDLGTANTLIYVREEGIVLNEPSVVAIRGERSGSGQKSVAAVGTEA 60 M KK RG+FSNDLSIDLGTANTLIYV+ +GIVLNEPSVVAIR +R KSVAAVG +A Sbjct: 1 MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDR-AGSPKSVAAVGHDA 59 Query: 61 KQMLGRTPGNIQAIRPMKDGVIADFYVTEKMLQHFIKQVHNNSVFRPSPRVLVCVPVGAT 120 KQMLGRTPGNI AIRPMKDGVIADF+VTEKMLQHFIKQVH+NS RPSPRVLVCVPVGAT Sbjct: 60 KQMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGAT 119 Query: 121 QVERRAIRESAMGAGAREVYLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAIISLN 180 QVERRAIRESA GAGAREV+LIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVA+ISLN Sbjct: 120 QVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLN 179 Query: 181 GVVYSSSVRIGGDKFDDAIINYVRRNYGSLIGEATAERIKHTIGTAYPGDEVLEIEVRGR 240 GVVYSSSVRIGGD+FD+AIINYVRRNYGSLIGEATAERIKH IG+AYPGDEV EIEVRGR Sbjct: 180 GVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGR 239 Query: 241 NLAEGVPRSFTLNSNEILEALQEPLSGIVSAVMVALEQSPPELASDISERGMVLTGGGAL 300 NLAEGVPR FTLNSNEILEALQEPL+GIVSAVMVALEQ PPELASDISERGMVLTGGGAL Sbjct: 240 NLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGAL 299 Query: 301 IRDLDRLLMQETGIPVMIADDPLTCVARGGGRALEMIDMHGGDLFSEE 348 +R+LDRLLM+ETGIPV++A+DPLTCVARGGG+ALEMIDMHGGDLFSEE Sbjct: 300 LRNLDRLLMEETGIPVVVAEDPLTCVARGGGKALEMIDMHGGDLFSEE 347
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 42.4 bits (99), Expect = 2e-05 Identities = 27/98 (27%), Positives = 49/98 (50%), Gaps = 14/98 (14%) Query: 347 IFEGYIDAPETGEYTFAIDGDDAIELLIDGEVITGFYGAHGTCNCTRYQGKVSLEQG-AH 405 I+ G+I ++ EYTFA D+ + + +D + N K+ LE+G + Sbjct: 93 IWSGFIKVKKSDEYTFATSADNHVTMWVDDQ---------EVINKASNSNKIRLEKGRLY 143 Query: 406 TIELRFHEAFGSE---AFRLYWQTPSSNRFEIVPADNL 440 I++++ +E F+LYW S N+ E++ +DNL Sbjct: 144 QIKIQYQRENPTEKGLDFKLYWTD-SQNKKEVISSDNL 180
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 34.9 bits (80), Expect = 1e-04 Identities = 13/29 (44%), Positives = 21/29 (72%) Query: 20 RSRGFTLVEMITVVIILGVLVLGVSSFLL 48 + RGFTL+E++ V++I+GVL V L+ Sbjct: 6 KQRGFTLLEIMVVIVIIGVLASLVVPNLM 34
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 33.5 bits (76), Expect = 4e-04 Identities = 14/69 (20%), Positives = 26/69 (37%), Gaps = 2/69 (2%) Query: 10 KRQTQKAFTLIELVVGMVVISIAFVLLSTMLFPQAERAADTLHRVRTAELAHSILNEIWG 69 K T + ++L +L G +++A +L L + R +T L + E Sbjct: 3 KNNTNRHYSLRKLKTGTASVAVALTVLGAGLVVNTNEVSAVATRSQTDTL--EKVQERAD 60 Query: 70 KRYDQNTNA 78 K +N Sbjct: 61 KFEIENNTL 69
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 45.3 bits (107), Expect = 8e-09 Identities = 19/69 (27%), Positives = 36/69 (52%), Gaps = 8/69 (11%) Query: 1 MHRAQRHAGFTLVELVTTIILIAILAVVVVPRLLTSSSYSAFTLRDEFISELRKVQIMAM 60 M + GFTL+E++ I++I +LA +VVP L+ + +++ + I+A+ Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGN--------KEKADKQKAVSDIVAL 52 Query: 61 NNQDRCYRL 69 N Y+L Sbjct: 53 ENALDMYKL 61
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 48.0 bits (114), Expect = 8e-10 Identities = 18/54 (33%), Positives = 31/54 (57%), Gaps = 4/54 (7%) Query: 2 KMQKQNGFTLIELVVVIIILGILAVTAAPKFINLQGDAR----LSTLQGVKGAI 51 KQ GFTL+E++VVI+I+G+LA P + + A +S + ++ A+ Sbjct: 3 ATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENAL 56
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 47.6 bits (113), Expect = 2e-09 Identities = 18/53 (33%), Positives = 30/53 (56%), Gaps = 4/53 (7%) Query: 1 MQKQNGFTLIELVVVIIILGILAVTAAPKFINLQSDARA----SALQGVKGAI 49 KQ GFTL+E++VVI+I+G+LA P + + A S + ++ A+ Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENAL 56
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 42.6 bits (100), Expect = 1e-07 Identities = 14/35 (40%), Positives = 27/35 (77%) Query: 6 QKGFSLIELVIVIVILGLLAATAIPRFLNVTDDAE 40 Q+GF+L+E+++VIVI+G+LA+ +P + + A+ Sbjct: 7 QRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKAD 41
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 301 bits (773), Expect = e-101 Identities = 109/406 (26%), Positives = 205/406 (50%), Gaps = 4/406 (0%) Query: 1 MPTYQYRGRSAQGEQIKGQVDASSESAAADQLMSRGVIPLEL----VLAKEVKEFSLKAL 56 M Y Y+ AQG++ +G +A S A L RG++PL + ++ L Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 57 FKGKVALEELQIFTRQMYSLTRSGIPILRAIAGLSETTHSVRMKEALDDISAQLTSGRPL 116 K +++ +L + TRQ+ +L + +P+ A+ +++ + + + + + +++ G L Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 117 SSAMNQHPDVFDALFVSMVHVGENTGKLEDAFIQLSGYIEREQETRRRIKAAMRYPIFVL 176 + AM P F+ L+ +MV GE +G L+ +L+ Y E+ Q+ R RI+ AM YP + Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 177 IAIAIAMVILNIMVIPKFAEMFSRFGADLPWATKILINTSNLFVNYWPAMIIALIGTFVG 236 + + IL +V+PK E F LP +T++L+ S+ + P M++AL+ F+ Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMA 240 Query: 237 IRYWHSTEKGEKQWDKWKLNIPVVGSIIERSTLSRYCRSFSMMLSAGVPMTQALSLVADA 296 R EK + + L++P++G I +RY R+ S++ ++ VP+ QA+ + D Sbjct: 241 FRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 297 VDNAYMHDRIVGMRRGIESGESMLRVSNNCQLFTPLVLQMVAVGEETGQIDQLLNDAADF 356 + N Y R+ + G S+ + LF P++ M+A GE +G++D +L AAD Sbjct: 301 MSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADN 360 Query: 357 YEGEVDYDLKNLTAKLEPILIGFVACIVLVLALGIYLPMWDMLNVV 402 + E + EP+L+ +A +VL + L I P+ + ++ Sbjct: 361 QDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 37.6 bits (87), Expect = 3e-05 Identities = 22/109 (20%), Positives = 44/109 (40%) Query: 321 VQQAAGQNEQALKSLAMIPDASELAIKKWHQQSDLAQKQQDYPVAEQSFRQLAKHEPYQG 380 Q A + ++AM+ + S +++ + + + Y A + F+ L + Y Sbjct: 11 YQLAMESFLKGGGTIAMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDS 70 Query: 381 RWWMGLGYALDAQQKYTEAKLAYNQALSQGNLSAQAKVYVDNRLLQLGA 429 R+++GLG A +Y A +Y+ + + LLQ G Sbjct: 71 RFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGE 119
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 166 bits (422), Expect = 2e-46 Identities = 73/307 (23%), Positives = 136/307 (44%), Gaps = 28/307 (9%) Query: 243 GNTGGGRQVVVT--PQAGLVTVRAYPNEIRQIRNFIKTAESHLQRQVILEAKVLEVTLSD 300 + +++ Q + V A P+ + + I + + QV++EA + EV +D Sbjct: 302 PVAALDKNIIIKAHGQTNALIVTAAPDVMNDLERVIAQLDIR-RPQVLVEAIIAEVQDAD 360 Query: 301 GYQQGIHWESVL-GHAGSTDITFGTSPTTGLSDQ-------ISSVLGGVTSIK-----LE 347 G GI W + G T+ S ++Q SS+ ++S Sbjct: 361 GLNLGIQWANKNAGMTQFTNSGLPISTAIAGANQYNKDGTVSSSLASALSSFNGIAAGFY 420 Query: 348 GSDFSTMISLLDTQGDVDVLSSPRVTASNNQKAVIKVGTDEYFVTNVSSTTVASNTPITT 407 +++ +++ L + D+L++P + +N +A VG + +T S T + + T Sbjct: 421 QGNWAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVPVLT--GSQTTSGDNIFNT 478 Query: 408 PDVELTPFFSGIALDVTPQIDEQGNVLLHIHPSVIDIKEQTKIIKISGSTLELPLAQSEI 467 + + GI L V PQI+E +VLL I V + + S ++ +L + Sbjct: 479 VERKTV----GIKLKVKPQINEGDSVLLEIEQEVSSVADAA-----SSTSSDLGATFN-T 528 Query: 468 RESDTVIKAASGDVVVIGGLMKSENTEIVSKVPLLGDIPFLGEAFTNRANSTVKTELVIL 527 R + + SG+ VV+GGL+ ++ KVPLLGDIP +G F + + K L++ Sbjct: 529 RTVNNAVLVGSGETVVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRNLMLF 588 Query: 528 LKPIVVG 534 ++P V+ Sbjct: 589 IRPTVIR 595
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 30.1 bits (67), Expect = 0.001 Identities = 20/62 (32%), Positives = 29/62 (46%), Gaps = 6/62 (9%) Query: 44 QLEFNGTSKIVINKQEPLHEIWLATQFGGYHFAYVDGKW------MDERNGNEFLPFVVE 97 +L+ G S ++ N QEP L GGY F Y +GK+ +D L F+V+ Sbjct: 164 ELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVD 223 Query: 98 SI 99 I Sbjct: 224 LI 225
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 300 bits (770), Expect = 2e-99 Identities = 91/441 (20%), Positives = 195/441 (44%), Gaps = 11/441 (2%) Query: 20 MMTDAPASHRLTIWALTALIITFLLWAYFAELDQVTTGMGKVIPSSQVQVIQSLDGGVLQ 79 + T RL + + ++ + + +++ V T GK+ S + + I+ ++ +++ Sbjct: 49 IETPVSRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVK 108 Query: 80 EMYVQEGLIVTKGQPLVRIDATRFQSDFAQQEQEVNSLSANVIRLNAELNSITISAITND 139 E+ V+EG V KG L+++ A ++D + + + R SI Sbjct: 109 EIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSI-------- 160 Query: 140 WREQVKISPQALIFPSSLEDSEPELTSRQREEYVGRLDNLSNQLEIQARQIQQRNQEIQE 199 E K+ L ++ E R + NQ + + ++ E Sbjct: 161 --ELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLT 218 Query: 200 LASKIRTLTTSFQLVSRELELTRPLADKGIVPEVELLKLQRVVNDIQGELASLRLLRPKV 259 + ++I ++ L+ L K + + +L+ + + EL + ++ Sbjct: 219 VLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQI 278 Query: 260 KSTMDEAILKRRESVLIYAADTRAQLNEMQTKLSRMNEAQVGAQDKVSKAEIVSPVNGTV 319 +S + A + + ++ + +L + + + +++ + I +PV+ V Sbjct: 279 ESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKV 338 Query: 320 KTVHINTLGGVVQPGVDIIEIVPSEDKLLIETKIVPKDIAFLHPGLPAVVKVTAYDFTRY 379 + + ++T GGVV ++ IVP +D L + + KDI F++ G A++KV A+ +TRY Sbjct: 339 QQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRY 398 Query: 380 GGLNGVVEHISADTTQDEEGNSFYIVKVRTEFSSLTKDDGTEMPIIPGMLTSVDVITGQR 439 G L G V++I+ D +D+ + V + E + L+ +P+ GM + ++ TG R Sbjct: 399 GYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCLS-TGNKNIPLSSGMAVTAEIKTGMR 457 Query: 440 SVLEYILNPILRAKDTALRER 460 SV+ Y+L+P+ + +LRER Sbjct: 458 SVISYLLSPLEESVTESLRER 478
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 84.6 bits (209), Expect = 8e-22 Identities = 33/118 (27%), Positives = 55/118 (46%), Gaps = 12/118 (10%) Query: 76 KVLFANDSYYIDPQYYPQVEVIATFMRDY--PNTQAVIEGHCSKTGSHEHNQVLSQNRAN 133 VLF + + P+ ++ + + + + + V+ G+ + GS +NQ LS+ RA Sbjct: 220 DVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQ 279 Query: 134 AVSSLLAERFGIDSDRLSAVGYSFDRPV-----DPTHTRAAHK----VNRRVIAELTG 182 +V L + GI +D++SA G PV D RAA +RRV E+ G Sbjct: 280 SVVDYLISK-GIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKG 336
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 62.7 bits (152), Expect = 2e-14 Identities = 29/145 (20%), Positives = 53/145 (36%), Gaps = 10/145 (6%) Query: 21 YELILRAAEKIIAAGGIQGLSMQLVATEAGVAAGTIYRYFKDKDQLILELRKDVLSQVAS 80 + IL A ++ + G+ S+ +A AGV G IY +FKDK L E+ + S + Sbjct: 13 RQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGE 72 Query: 81 AILE--DHQIGTIEQRFKRIWMKMYNYGKQP-------SPANLSYEQYANLPVINTQEIR 131 LE G + I + + E + V+ Q R Sbjct: 73 LELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQ-QAQR 131 Query: 132 QLEMQLFAPLQQLFEQGKAQGLIQP 156 L ++ + ++Q + ++ Sbjct: 132 NLCLESYDRIEQTLKHCIEAKMLPA 156
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 47.1 bits (112), Expect = 6e-08 Identities = 20/96 (20%), Positives = 36/96 (37%), Gaps = 1/96 (1%) Query: 71 TIANQVSGVVSAIRFENGSKVEVGQMLIELDSKVEKANLKSKQVQLPAAEADFKRLSKLY 130 I + +V I + G V G +L++L + +A+ Q L A + R L Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILS 157 Query: 131 KQ-NSVSKQDLDNSQSKYLALMADSESLSATIGRRE 165 + +L Y +++ E L T +E Sbjct: 158 RSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKE 193 Score = 43.7 bits (103), Expect = 7e-07 Identities = 36/215 (16%), Positives = 81/215 (37%), Gaps = 28/215 (13%) Query: 78 GVVSAIRFENGSKVEVGQMLIEL--DSKVEKANLKSKQVQLPAAEADFKRLSKLYKQNSV 135 ++ +E +E + +V K+ L+ + ++ +A+ +++ +++L+ +N + Sbjct: 247 QAIAKHAV-----LEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLF-KNEI 300 Query: 136 SKQDLDNSQSKYLALMADSESLSATIGRREIRAPFAGLVGIRNVN-LGEYLQTGS---EI 191 + L + L + IRAP + V V+ G + T I Sbjct: 301 LDK-LRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVI 359 Query: 192 VRLEDISTMKIRFTIPQTQLSRIATGQKVHVYVDAYP---TEPFEGVISAIEP------- 241 V +D T+++ + + I GQ + V+A+P G + I Sbjct: 360 VPEDD--TLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQR 417 Query: 242 -AVFYQSGLIQVQARIP--NTDAKLRSGMFAKVDI 273 + + + + + N + L SGM +I Sbjct: 418 LGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEI 452
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 795 bits (2054), Expect = 0.0 Identities = 312/1037 (30%), Positives = 533/1037 (51%), Gaps = 34/1037 (3%) Query: 5 DIFIRRPVLAASISFLILLLGFYALKSMQVREYPEMTNTVVTVSTSYYGADSNLIQGFIT 64 + FIRRP+ A ++ ++++ G A+ + V +YP + V+VS +Y GAD+ +Q +T Sbjct: 3 NFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVT 62 Query: 65 QPLEQALAQADNVDFMTSDSF-LGSSKISVYMKLNTDPNGALADILAKVNSVRSQLPKEA 123 Q +EQ + DN+ +M+S S GS I++ + TDP+ A + K+ LP+E Sbjct: 63 QVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEV 122 Query: 124 EDSTVEMSTGAQTSALYISFYSDQINSSQ--ITDYLERVVKPELFTIDGVAKVNLYGGIK 181 + + + + + + F SD ++Q I+DY+ VK L ++GV V L+G + Sbjct: 123 QQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA-Q 181 Query: 182 YAMRIWLDPARMGGFNLSSTDVMSVLQANNYQSAVGQTNNTFTL------LNGTADTQVA 235 YAMRIWLD + + L+ DV++ L+ N Q A GQ T L + A T+ Sbjct: 182 YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK 241 Query: 236 TVAELEKLVI-GSKDGLVIRLGDIADVSLEKSHDVYRALADGQEAVVVGLDVTPTANPLV 294 E K+ + + DG V+RL D+A V L + A +G+ A +G+ + AN L Sbjct: 242 NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALD 301 Query: 295 VAADARAMMPQITRNLPISMKARILYDSSLAIDESINEVIKTIGEASLIVIVVITLFLGS 354 A +A + ++ P MK YD++ + SI+EV+KT+ EA ++V +V+ LFL + Sbjct: 302 TAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQN 361 Query: 355 FRAVIIPIVTIPLSLIGVAVIMQMFGFTLNLMTLLAMVLAIGLVVDDAIVVVENVDRHIK 414 RA +IP + +P+ L+G I+ FG+++N +T+ MVLAIGL+VDDAIVVVENV+R + Sbjct: 362 MRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 415 LGETPFRAAII-GTREIAVPVISMTITLAAVYAPIALMGGITGSLFKEFALTLAGAVFIS 473 + P + A +I ++ + + L+AV+ P+A GG TG+++++F++T+ A+ +S Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 474 GIVALTLSPMMCSKILKA-----HSKPNRFERGVENFLSGLTSRYNRMLTAVLNKRPVVI 528 +VAL L+P +C+ +LK H F + Y + +L + Sbjct: 482 VLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYL 541 Query: 529 AFAIIVFASLPVMFSFIPSELAPNEDKSVVMMMGTAPSSANLDYIQANMTLVTDMISAQP 588 ++ A + V+F +PS P ED+ V + M P+ A + Q + VTD Sbjct: 542 LIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNE 601 Query: 589 EAAASLAF----VGVPNANQAFGIA--PLVPWSERDKSQKEMQKFFGE---EVKKVPGMA 639 +A F Q G+A L PW ER+ + + E+ K+ Sbjct: 602 KANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGF 661 Query: 640 VTTFQMPE--LPGASSGLPIQFVITSSNSFESLFQIGSGVLNKVQQSPLFVYS-EVNLKF 696 V F MP G ++G + + + ++L Q + +L Q P + S N Sbjct: 662 VIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLE 721 Query: 697 DSGSMKIHIKRDVAGAYGITMKDIGLTLTTMMSDGYVNRINLDGRSYEVIPQVERKLRAN 756 D+ K+ + ++ A A G+++ DI T++T + YVN GR ++ Q + K R Sbjct: 722 DTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRML 781 Query: 757 PEALAGYYLTAADGRSIPLSSLVDVEIVSEPRSLPHFNQMNAITVGGVAAPGVAIGDAIA 816 PE + Y+ +A+G +P S+ V L +N + ++ + G AAPG + GDA+A Sbjct: 782 PEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMA 841 Query: 817 FLQNIGDNELPKGYSYDFLGEARQYVTEGSALYATFGLALAIIFLVLASQFESLRDPLVI 876 ++N+ ++LP G YD+ G + Q G+ A ++ ++FL LA+ +ES P+ + Sbjct: 842 LMENL-ASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900 Query: 877 LVSVPLAISGALIALGWTHVFGLSSMNIYTQVGLITLVGLITKHGILMCEVAKEEQLHNG 936 ++ VPL I G L+A + ++Y VGL+T +GL K+ IL+ E AK+ G Sbjct: 901 MLVVPLGIVGVLLAATLFN----QKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEG 956 Query: 937 LSKLDAIKHAATIRLRPILMTTAAMIAGLIPLLFAVGAGAVARFNIGLVIVSGLAIGTVF 996 ++A A +RLRPILMT+ A I G++PL + GAG+ A+ +G+ ++ G+ T+ Sbjct: 957 KGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLL 1016 Query: 997 TLFVLPVIYTYLAEKHE 1013 +F +PV + + + Sbjct: 1017 AIFFVPVFFVVIRRCFK 1033
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 24.8 bits (54), Expect = 0.042 Identities = 15/50 (30%), Positives = 25/50 (50%), Gaps = 5/50 (10%) Query: 4 PKKIEEVAKQLSENLPGGLKQFAGEFEERSKQILQNQLQKLDVVSREEFE 53 + +AKQLS P EF E++ + ++L KLD S+++F Sbjct: 148 IIFAKNIAKQLSAKDPNN-----KEFYEKNLKEYTDKLDKLDKESKDKFN 192
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 30.5 bits (69), Expect = 0.007 Identities = 16/42 (38%), Positives = 18/42 (42%), Gaps = 6/42 (14%) Query: 205 DDQALLARKARHTAIERGIPVLISNHDIPLTRELYHGARFDT 246 D Q R A E G+P+L IPL R LY A D Sbjct: 289 DAQVQ---TVRKIAEEEGVPIL---QRIPLARALYWDALVDH 324
>HOKGEFTOXIC#Hok/Gef cell toxic protein family signature. Length = 52 Score = 27.5 bits (61), Expect = 0.017 Identities = 10/32 (31%), Positives = 19/32 (59%), Gaps = 3/32 (9%) Query: 224 VQLPQKSRLKMIIIVSTLCLIALLASWLLIDS 255 ++LP+ S + ++IV CL L+ ++L S Sbjct: 1 MKLPRSSLVWCVLIV---CLTLLIFTYLTRKS 29
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.5 bits (63), Expect = 0.016 Identities = 16/65 (24%), Positives = 24/65 (36%), Gaps = 10/65 (15%) Query: 9 LVGPMGAGKSTIGRHLAQMLHLEFHDSDQEIESRTGADIA------WVFDVEGEEGFRNR 62 L G G GKST+ L + SD + TG D +++ FR Sbjct: 601 LEGTGGIGKSTLINTLVGLDFF----SDTHFDIGTGKDSYEQIAGIVAYELSEMTAFRRA 656 Query: 63 ETQVV 67 + + V Sbjct: 657 DAEAV 661
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 245 bits (628), Expect = 4e-74 Identities = 100/412 (24%), Positives = 187/412 (45%), Gaps = 38/412 (9%) Query: 310 GDITLRLDDVPWDQALDLILQAKGLDKRIEGNILMIAPSEEIAIRESQEL-------KNR 362 GD ++ + W A D++ L+K + L + + E +R Sbjct: 190 GDRSVVTVPLSWASAADVVKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSGEPNSR 249 Query: 363 QEVKQLA-PLY--------SEYLQINYAKAKDIAALLKGEDSSLLTARG----------- 402 Q + + L ++ + + YAKA D+ +L G S++ + + Sbjct: 250 QRIIAMIKQLDRQQATQGNTKVIYLKYAKASDLVEVLTGISSTMQSEKQAAKPVAALDKN 309 Query: 403 -SVAVDERTNTLLVKDTEETLENVHRLIEVLDIPIKQVLIEARMVTVKDDVSEDLGVRWG 461 + +TN L+V + + ++ R+I LDI QVL+EA + V+D +LG++W Sbjct: 310 IIIKAHGQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLGIQWA 369 Query: 462 VTDQQGDKGTSGSLEGAGDIANGIVPSLSDRLNVNLPAAVANPTSIAFHVAKLADGTVLD 521 + + T+ L + IA + ++ +L +A+++ IA + Sbjct: 370 NKNAGMTQFTNSGLPISTAIAGANQYNKDGTVSSSLASALSSFNGIAAGFYQGN----WA 425 Query: 522 LELSALEQENKGEIIASPRITTSNQKAAYIEQGVEIPYVEASSSG-----ATTVTFKKAV 576 + L+AL K +I+A+P I T + A G E+P + S + TV K Sbjct: 426 MLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVPVLTGSQTTSGDNIFNTVERKTVG 485 Query: 577 LSLRVTPQITPDNRVILDLEITQDSQGKT-VDTPTGQAVSIDTQRIGTQVLVDHGETIVL 635 + L+V PQI + V+L++E S T + + +T+ + VLV GET+V+ Sbjct: 486 IKLKVKPQINEGDSVLLEIEQEVSSVADAASSTSSDLGATFNTRTVNNAVLVGSGETVVV 545 Query: 636 GGIYQQQLITKVSKVPILGDIPYLGFMFRNSSDKNERQELLIFVTPKIVSEA 687 GG+ + + KVP+LGDIP +G +FR++S K ++ L++F+ P ++ + Sbjct: 546 GGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRNLMLFIRPTVIRDR 597 Score = 43.4 bits (102), Expect = 3e-06 Identities = 30/175 (17%), Positives = 72/175 (41%), Gaps = 14/175 (8%) Query: 279 SLNFQNISVRTVLQIIADYNNFNLVTSDTVEGDITLR-LDDVPWDQALDLILQAKGLDKR 337 S +F+ ++ + ++ N ++ +V G IT+R D + +Q L Sbjct: 31 SASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRSYDMLNEEQYYQFFLSVL----D 86 Query: 338 IEGNILMIAPSEEIAIRESQELKNRQEVK--QLAP-----LYSEYLQINYAKAKDIAALL 390 + G ++ + + + S++ K AP + + + + A+D+A LL Sbjct: 87 VYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIGDEVVTRVVPLTNVAARDLAPLL 146 Query: 391 KGEDSSLLTARGSVAVDERTNTLLVKDTEETLENVHRLIEVLDIPIKQVLIEARM 445 + + + GSV E +N LL+ ++ + ++E +D + ++ + Sbjct: 147 RQLNDN--AGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDNAGDRSVVTVPL 199
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 45.5 bits (108), Expect = 2e-07 Identities = 31/156 (19%), Positives = 59/156 (37%), Gaps = 34/156 (21%) Query: 199 VDIGANITTFSVVEHGETTFVREQAFGGEQFTQSILSFYGMTY------EQAEKAKLE-- 250 VDIG T +V+ + GG++F ++I+++ Y AE+ K E Sbjct: 164 VDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIG 223 Query: 251 -------------------GDLPRNY------VFEVLSPFQTQLLQQIKRTLQIYCTSSG 285 +PR + + E L T ++ + L+ Sbjct: 224 SAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELA 283 Query: 286 RDKVDH-IVLCGGTSKLEGMANLMVNELGVHTIIAD 320 D + +VL GG + L + L++ E G+ ++A+ Sbjct: 284 SDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAE 319
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 36.0 bits (83), Expect = 4e-05 Identities = 19/55 (34%), Positives = 32/55 (58%), Gaps = 7/55 (12%) Query: 3 LKRIKTQRGFTLLEMLIAIAIFAMLGLAANTVLSTVMKNDIATRDFAAKLKAMQQ 57 ++ QRGFTLLE+++ I I +G+ A+ V+ +M N ++ A K KA+ Sbjct: 1 MRATDKQRGFTLLEIMVVIVI---IGVLASLVVPNLMGN----KEKADKQKAVSD 48
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 29.9 bits (67), Expect = 0.002 Identities = 9/31 (29%), Positives = 19/31 (61%) Query: 5 IKQRGMTLLEVIVALAVFSIAAVSITKSLGD 35 ++QRG TLLE+++ L + ++A + + Sbjct: 1 MRQRGFTLLEMMLILLLMGVSAGMVLLAFPA 31
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 85.4 bits (211), Expect = 3e-23 Identities = 39/170 (22%), Positives = 71/170 (41%), Gaps = 39/170 (22%) Query: 23 RQTGFTLMEVLLVVLLMGLAATAVTLSMGGASKEKALERTAQQFMMATEMVLDETVLSGH 82 RQ GFTL+E++L++LLMG++A V L+ + + A + T +F V + +G Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQ-TLARFEAQLRFVQQRGLQTGQ 60 Query: 83 FVGIVIEDSSYKFVYYDEG---------------KWKPLEQDRLLAERQMEPGVEMVLVL 127 F G+ + ++F+ + +W PL R+ + Sbjct: 61 FFGVSVHPDRWQFLVLEARDGADPAPADDGWSGYRWLPLRAGRVATSGS----------I 110 Query: 128 DGLPLVQEDEEQDSWFDEPLIEKSADDKKKFPEPQIMLFPSGEMSAFELS 177 G L + ++W D+ P +++FP GEM+ F L+ Sbjct: 111 AGGKLNLAFAQGEAW-------TPGDN------PDVLIFPGGEMTPFRLT 147
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 235 bits (602), Expect = 1e-83 Identities = 99/144 (68%), Positives = 121/144 (84%) Query: 1 MQTRNKQQGFTLLEVMVVIVILGILASMVVPNLMGNKDKADQQKAVSDIVALENALDMYK 60 M+ +KQ+GFTLLE+MVVIVI+G+LAS+VVPNLMGNK+KAD+QKAVSDIVALENALDMYK Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK 60 Query: 61 LDNSVYPTTEQGLEALVQKPTISPEPRNYRADGYVKRLPQDPWRSDYLLLSPGENGKLDI 120 LDN YPTT QGLE+LV+ PT+ P NY +GY+KRLP DPW +DY+L++PGE+G D+ Sbjct: 61 LDNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDL 120 Query: 121 FSAGPDGQPGTEDDIGNWNLQNFQ 144 SAGPDG+ GTEDDI NW L + Sbjct: 121 LSAGPDGEMGTEDDITNWGLSKKK 144
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 503 bits (1296), Expect = 0.0 Identities = 233/407 (57%), Positives = 304/407 (74%), Gaps = 1/407 (0%) Query: 1 MPAFEYKALDKTGKQQKGVVEADTARHARTQLREQRLMPLEITPVVEKESKAKSAGFSF- 59 M + Y+ALD GK+ +G EAD+AR AR LRE+ L+PL + + K+ S G S Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 60 LKRGISTAELALITRQIATLVAAGLPIEEALKAVGQQCEKDRLASMVMAVRSRVVEGYSL 119 K +ST++LAL+TRQ+ATLVAA +P+EEAL AV +Q EK L+ ++ AVRS+V+EG+SL Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 120 ADSMAEFPHIFDELYRAMVASGEKSGHLEVVLNRLADYTERRQQLKSKMTQAMIYPIVLT 179 AD+M FP F+ LY AMVA+GE SGHL+ VLNRLADYTE+RQQ++S++ QAMIYP VLT Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 180 VVAIGVIAILLAAVVPQVVGQFEHMGQELPWTTELLIASSDFIRDYGLIVLVAIVGLFFI 239 VVAI V++ILL+ VVP+VV QF HM Q LP +T +L+ SD +R +G +L+A++ F Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMA 240 Query: 240 AKRLLVTPKNRMIYDSMLLRLPVISKVSKSLNTARFARTLSILTASSVPLLDAMRIASDV 299 + +L K R+ + LL LP+I ++++ LNTAR+ARTLSIL AS+VPLL AMRI+ DV Sbjct: 241 FRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 300 LVNVKVKAAVEDATLRVREGTSLGTALANTKLFPPMMLYMITSGEKSGQLEQMLERAADN 359 + N + + AT VREG SL AL T LFPPMM +MI SGE+SG+L+ MLERAADN Sbjct: 301 MSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADN 360 Query: 360 QDREFESNVTIALGVFEPMLVVSMAAVVLFIVLAILQPILALNNMIS 406 QDREF S +T+ALG+FEP+LVVSMAAVVLFIVLAILQPIL LN ++S Sbjct: 361 QDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLMS 407
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 608 bits (1568), Expect = 0.0 Identities = 330/677 (48%), Positives = 448/677 (66%), Gaps = 29/677 (4%) Query: 6 IRRRLIAGMVMGASLLAPQLAWSEQYAANFKGTDIQEFINIVGKNLERTIIVDPTVRGKI 65 IR + ++ A L P A +E+++A+FKGTDIQEFIN V KNL +T+I+DP+VRG I Sbjct: 7 IRSFSLTLLIFAALLFRP--AAAEEFSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTI 64 Query: 66 NVRSYDLLNDEQYYQFFLNVLQVYGYAVVEMDNNIIKVIKDKDAKTASIRVADDSAPGLG 125 VRSYD+LN+EQYYQFFL+VL VYG+AV+ M+N ++KV++ KDAKTA++ VA D+APG+G Sbjct: 65 TVRSYDMLNEEQYYQFFLSVLDVYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIG 124 Query: 126 DEMVTRIVALYNTEAKQLAPLLRQLNDNAGGGNVVNYDPSNVLMISGRAAVVNKLVEIVR 185 DE+VTR+V L N A+ LAPLLRQLNDNAG G+VV+Y+PSNVL+++GRAAV+ +L+ IV Sbjct: 125 DEVVTRVVPLTNVAARDLAPLLRQLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVE 184 Query: 186 RVDKQGDTAVEVVRLEYASAGEIVRIIDTLYRSTANQAQMPGQAPKVVADERINAVVVSG 245 RVD GD +V V L +ASA ++V+++ L + T+ A VVADER NAV+VSG Sbjct: 185 RVDNAGDRSVVTVPLSWASAADVVKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSG 244 Query: 246 DEKSRERVVKLIKKLDAEQATTGNTKVRYLRYAKAEDLVEVLTGFAEQLVDDKGAPQGGG 305 + SR+R++ +IK+LD +QAT GNTKV YL+YAKA DLVEVLTG + + +K A + Sbjct: 245 EPNSRQRIIAMIKQLDRQQATQGNTKVIYLKYAKASDLVEVLTGISSTMQSEKQAAKPVA 304 Query: 306 SKRRNEINIMAHTDTNALVISAEPDQMRTIESVINQLDIRRAQVLVEAIIVEVAEGDDVG 365 + +N I I AH TNAL+++A PD M +E VI QLDIRR QVLVEAII EV + D + Sbjct: 305 ALDKN-IIIKAHGQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLN 363 Query: 366 FGVQWATEAGGGTQFNNLGPTIGEIGAGIWQAQGEEGSTVCNDGTCTENPDTRGDITLLA 425 G+QWA + G TQF N G I AG + DGT + + LA Sbjct: 364 LGIQWANKNAGMTQFTNSGLPISTAIAG--------ANQYNKDGTVS---------SSLA 406 Query: 426 QALGKVNGMAWGVAMGDFGALIQAVSSDTKSNVLATPSITTLDNQEASFIVGDEVPILTG 485 AL NG+A G G++ L+ A+SS TK+++LATPSI TLDN EA+F VG EVP+LTG Sbjct: 407 SALSSFNGIAAGFYQGNWAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVPVLTG 466 Query: 486 SQNSSNGNSNPFQTVERKEVGVKLKVVPQVNEGNAVKLTIEQEVSGINGK-----TGVDV 540 SQ +S N F TVERK VG+KLKV PQ+NEG++V L IEQEVS + + + Sbjct: 467 SQTTSGD--NIFNTVERKTVGIKLKVKPQINEGDSVLLEIEQEVSSVADAASSTSSDLGA 524 Query: 541 TFATRRLTTTVMADSGQIVVLGGLIKEEVQESVQKVPFLGDIPIIGHLFKSSSSGKKKTN 600 TF TR + V+ SG+ VV+GGL+ + V ++ KVP LGDIP+IG LF+S+S K N Sbjct: 525 TFNTRTVNNAVLVGSGETVVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRN 584 Query: 601 LMVFIKPTIIRDGITMEGIAGRKYNYFRALQLEQQ-ERGVNLMPNTDVPILEEWNQADYL 659 LM+FI+PT+IRD + +Y F Q +Q+ + + M N D+ + Q Sbjct: 585 LMLFIRPTVIRDRDEYRQASSGQYTAFNDAQSKQRGKENNDAMLNQDLLEIYP-RQDTAA 643 Query: 660 PPEVNEVLNRYKEGKGL 676 +V+ ++ + G L Sbjct: 644 FRQVSAAIDAFNLGGNL 660
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 200 bits (509), Expect = 3e-65 Identities = 77/286 (26%), Positives = 136/286 (47%), Gaps = 36/286 (12%) Query: 17 KPVSTAVFGLGLLIALYLLAQITWKL-VPDNSAATRWVPTPVASNASGQVNILGLQQLSL 75 + +F L +L+ LA I W++ +PDN+ + TP + L +L Sbjct: 12 SVIRRILFYLLMLLFCQQLAMIFWRIGLPDNAPVSSVQITPAQARQQPV----TLNDFTL 67 Query: 76 FGQPDAAGAKPKAAPVEE--IITDAPKTSLSIQLTGVVASTTEQKGLAVIASSGSQDTYG 133 FG + A + +++ P ++L++ LTGV+A + + +A+I+ Q + G Sbjct: 68 FG----VSPEKNKAGALDASQMSNLPPSTLNLSLTGVMAGDDDSRSIAIISKDNEQFSRG 123 Query: 134 LGDKIRGTSASLKEVYADRIIITNSGRYETLMLDGLEYNTNGAANQHLQKAKSVSKGKTI 193 + +++ G +A + + DR+++ GRYE L L E + G + Sbjct: 124 VNEEVPGYNAKIVSIRPDRVVLQYQGRYEVLGLYSQEDS-----------GSDGVPGAQV 172 Query: 194 DNRKNRAVAAELSQSREEILADPSKITDYLSISPVKSGGELAGYRLNPGKDRELFKQAGF 253 + E Q R + ++DY+S SP+ + +L GYRLNPG + F + G Sbjct: 173 N---------EQLQQR-----ASTTMSDYVSFSPIMNDNKLQGYRLNPGPKSDSFYRVGL 218 Query: 254 KANDLAKSINGYDLTDMGQALEVMAQLPEMTEVALMVERDGQLIEI 299 + ND+A ++NG DL D QA + M ++ ++ L VERDGQ +I Sbjct: 219 QDNDMAVALNGLDLRDAEQAKKAMERMADVHNFTLTVERDGQRQDI 264
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 28.4 bits (63), Expect = 0.029 Identities = 23/102 (22%), Positives = 37/102 (36%), Gaps = 1/102 (0%) Query: 145 DGSGDLWIKGGHDLNTQDGSGSVEISNTTGKLTLEDGSGSITLSGIGGDTHIDDGSGDLN 204 DG + G+D D G+ +S G L G G+ L G+ G+ +++ G GD Sbjct: 744 DGDDLIEGNDGNDRLYGD-KGNDTLSGGNGDDQLYGGDGNDKLIGVAGNNYLNGGDGDDE 802 Query: 205 VNNVNGRVVIDDGSGDIDVDNTLGLSIIESGSGDLSVDNING 246 + + G D G + G D + G Sbjct: 803 FQVQGNSLAKNVLFGGKGNDKLYGSEGADLLDGGEGDDLLKG 844
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.0 bits (67), Expect = 0.007 Identities = 22/86 (25%), Positives = 38/86 (44%), Gaps = 20/86 (23%) Query: 44 KEGDRIVVDKMA---YDLRVPFTQISLATTGEPERGEIVVFESKAADKRLIKRVIGLPGD 100 K+GD++VV K A + L+V TGEP E+ +F++ A + D Sbjct: 909 KQGDKVVVTKSATGNFTLQVA------DKTGEPNHNELTLFDASKAQR-----------D 951 Query: 101 KISLSHEVLFINGKALDYSLVTSDQR 126 +++S ++ A Y L + R Sbjct: 952 HLNVSLVGNTVDLGAWKYKLRNVNGR 977
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 27.5 bits (61), Expect = 0.045 Identities = 15/68 (22%), Positives = 25/68 (36%), Gaps = 4/68 (5%) Query: 79 QLPPMVSDNNSQY---GTAFTVSIEAKQGVTTGVSAADRVTTIKTAIADNAKPDDLARPG 135 Q P + F + ++ ++ GVS +D TI TA+ +D G Sbjct: 707 QHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALG-GTYVNDFIDRG 765 Query: 136 HVYPLRAR 143 V L + Sbjct: 766 RVKKLYVQ 773
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 31.3 bits (70), Expect = 0.027 Identities = 39/169 (23%), Positives = 68/169 (40%), Gaps = 21/169 (12%) Query: 58 NVIYELQKERGLSAGYLSSGGRAFKQRLEQ-QWLNTDRKFQELLQSSALEKTVETASNDA 116 V YE+ K G+S +S + L + L+ D +LL S ++ +E + Sbjct: 168 EVYYEIGK--GISLDIISKDKSLDPEFLNLIKSLSDDSDSSDLLFSQKFKEKLELNNKSI 225 Query: 117 ELFHALQN----QLSKASLARQQLEIARQKVLELNTPEYFNFYSGLTQKLINFVSLLRFK 172 ++ +N Q + + + VLEL P+ F + + L + K Sbjct: 226 DINFIKENLTEFQHAFSLAFSYYFAPDHRTVLELYAPDMFEYMNKLEKGGFE-KISESLK 284 Query: 173 SDNSYQVLVQSDLINMLKIQELAGQERGLVNSLLAAPTLEPDSFKQIAQ 221 + V+ D I++LK E A + GLV D+FK+IA+ Sbjct: 285 KEG-----VEKDRIDVLK-GEKALKASGLVPE-------HADAFKKIAR 320
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.0 bits (70), Expect = 0.007 Identities = 15/73 (20%), Positives = 28/73 (38%), Gaps = 5/73 (6%) Query: 199 LGGKDYHAEPFDKNDLTHSKLRYDDYRELYRQQPQLQLGSPTNHWLV---ESIDAAEQAI 255 G DY +PFD +L R + R+ +L+ S LV ++ + + Sbjct: 96 KGAYDYLPKPFDLTELIGIIGRALAEPK--RRPSKLEDDSQDGMPLVGRSAAMQEIYRVL 153 Query: 256 DAARNSKIPLLIL 268 + + L+I Sbjct: 154 ARLMQTDLTLMIT 166
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 313 bits (804), Expect = e-107 Identities = 111/352 (31%), Positives = 186/352 (52%), Gaps = 6/352 (1%) Query: 10 KTEKATPQKLKKAREQGQVPRSKDLASSALIIGCSLLLTTTADWIAAKVAAMTRINMSFT 69 KTE+ TP+K++ AR++GQV +SK++ S+ALI+ S +L +D+ + + M Sbjct: 5 KTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKL----MLIP 60 Query: 70 KAQLDEPGMMARHLAYS--LLEVLNILGPLFLMVALIAMVAGAMPGGPIFNFNNANFKYS 127 Q P A LLE + PL + AL+A+ + + G + + Sbjct: 61 AEQSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDIK 120 Query: 128 RIDPIAGLGRMASVKSLVELVKSILKIVLLIGIMLLFLQKNFQALMAVSQLPIDEAVTRG 187 +I+PI G R+ S+KSLVE +KSILK+VLL ++ + ++ N L+ + I+ Sbjct: 121 KINPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLL 180 Query: 188 IEMLSLAMFYMGLGLLVITFIDVPYQYWHHHKELRMSLQEVKDEYKQQDGKPEVKAKIRQ 247 ++L M +G +VI+ D ++Y+ + KEL+MS E+K EYK+ +G PE+K+K RQ Sbjct: 181 GQILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKRRQ 240 Query: 248 MQQRISRSRADVSVPKADVLLVNPSHYAVALKYDMNKADAPYVLAKGTDELALYMRDIAK 307 Q I +V ++ V++ NP+H A+ + Y + P V K TD +R IA+ Sbjct: 241 FHQEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIAE 300 Query: 308 RNDVEVLELPPLTRAIYYSTQVEQQIPSGLFIAIAHVLTYVMQLRAARQGQQ 359 V +L+ PL RA+Y+ V+ IP+ A A VL ++ + +Q + Sbjct: 301 EEGVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQNIEKQHSE 352
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 107 bits (269), Expect = 2e-30 Identities = 78/229 (34%), Positives = 115/229 (50%), Gaps = 2/229 (0%) Query: 1 MVMPFLGNAYIPATVRILLAISISALIAPMLPPFPAVDAISFQALILAVEQLLIGFMLAL 60 P L +P V++ LA+ I+ IAP LP SF AL LAV+Q+LIG L Sbjct: 28 STAPILSERSVPKRVKLGLAMMITFAIAPSLPANDVPV-FSFFALWLAVQQILIGIALGF 86 Query: 61 FLSIMIHVMTLFGAMMSMQMGLSMAVMNDPSSGGANPILGLWFMLYGTLLFLALDGHLVA 120 + + G ++ +QMGLS A DP+S P+L + LLFL +GHL Sbjct: 87 TMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHLNMPVLARIMDMLALLLFLTFNGHLWL 146 Query: 121 IGILVDSFHLWPIG-MGVFDLPLMGLIARFSWIFAAAFMLALPAILAMLVVNLTFGVLSR 179 I +LVD+FH PIG + + L S IF MLALP I +L +NL G+L+R Sbjct: 147 ISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLIFLNGLMLALPLITLLLTLNLALGLLNR 206 Query: 180 AAPSLNVFALGFPMSMLMGLLCVFFSFSGLPTRYSDLCLDALSAMYQFI 228 AP L++F +GFP+++ +G+ + + L + + + I Sbjct: 207 MAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFCEHLFSEIFNLLADII 255
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 49.4 bits (118), Expect = 1e-11 Identities = 19/79 (24%), Positives = 40/79 (50%) Query: 3 VNELTALFAEAIFLVVAMVGVLVVPGLLVGLFIAVFQAATQVNEQTLSFLPRLVITLLMV 62 +++L +A++LV+ + G + ++GL + +FQ TQ+ EQTL F +L+ L + Sbjct: 1 MDDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCL 60 Query: 63 VFAGEWLLMKICDFFDRLF 81 W + + ++ Sbjct: 61 FLLSGWYGEVLLSYGRQVI 79
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 237 bits (606), Expect = 4e-81 Identities = 112/238 (47%), Positives = 162/238 (68%) Query: 4 VLLVFVLSFSSAAYASDGLTLFSLADGDKTQAVSVKLEILALMTVLSFLPALLMMLTSFT 63 + +L + + + S Q+ S+ ++ L +T L+F+PA+L+M+TSFT Sbjct: 6 SVAPVLLWLITPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLMMTSFT 65 Query: 64 RIIVVLAILRQALGLQQSPPNKVLIGIALVMTIFIMRPVGQEIYDDAFLPYDMGQIELPE 123 RII+V +LR ALG +PPN+VL+G+AL +T FIM PV +IY DA+ P+ +I + E Sbjct: 66 RIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEKISMQE 125 Query: 124 AVARGEVPLRQFMLAQTRETDLEQMLKIADEPITLTADEIPFFVLMPAFVLSELKTAFQI 183 A+ +G PLR+FML QTRE DL ++A+ + +P +L+PA+V SELKTAFQI Sbjct: 126 ALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELKTAFQI 185 Query: 184 GFLLFLPFLVIDLVVASVLMSMGMMMLSPLIISLPFKLMVFVLVDGWSMTVSTLVASY 241 GF +F+PFL+IDLV+ASVLM++GMMM+ P I+LPFKLM+FVLVDGW + V +L S+ Sbjct: 186 GFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLAQSF 243
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 80.3 bits (198), Expect = 9e-23 Identities = 41/125 (32%), Positives = 67/125 (53%), Gaps = 17/125 (13%) Query: 1 MAEHNILQDEDFLLDDDFFAEEQSHKPKVQAK-----------------PVKDMSFFHQL 43 M++ N DE+ DD +A+ + + K ++D+ + Sbjct: 1 MSDMNNPSDENTGALDDLWADALNEQKATTTKSAADAVFQQLGGGDVSGAMQDIDLIMDI 60 Query: 44 PVHVTLELASVEMSLGELAQMGEGDVVALDRMVGEPLDIRVNGALLGRGEVVEVNGRYGV 103 PV +T+EL M++ EL ++ +G VVALD + GEPLDI +NG L+ +GEVV V +YGV Sbjct: 61 PVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGV 120 Query: 104 RLLEV 108 R+ ++ Sbjct: 121 RITDI 125
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 31.4 bits (71), Expect = 0.004 Identities = 17/93 (18%), Positives = 37/93 (39%), Gaps = 7/93 (7%) Query: 184 LCFYMAEHLLELMAEQP----SQYQADPELSLKLAHRLKQIPLRTLLELGHQSMPVTSLQ 239 + + E ++ ++ Q + + + L +L + + + E+G + V + Sbjct: 217 IPYITIEPIISKLSSQFWFSSVRRSSTTQYMGVLRDKLSTVDMDVVAEVGSLRLSVRDIL 276 Query: 240 SLAVGDILPMN-LHSRCPVT--VGKRPLFYATV 269 L VGDI+ ++ H P +G R F Sbjct: 277 GLRVGDIIRLHDTHVGDPFVLSIGNRKKFLCQP 309
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 29.9 bits (67), Expect = 0.032 Identities = 13/41 (31%), Positives = 21/41 (51%) Query: 358 ETKAISGLFFAGQINGTTGYEEAGAQGLLAGMNASLQVQGK 398 ++ + + G+ NG Y GL+ G+N +LQ QGK Sbjct: 135 DSYTYADNYMTGRANGVATYRNTDFFGLVDGLNFALQYQGK 175
>SECA#SecA protein signature. Length = 901 Score = 51.4 bits (123), Expect = 3e-09 Identities = 16/20 (80%), Positives = 18/20 (90%) Query: 294 QTGRNDPCPCGSGKKYKKCC 313 + GRNDPCPCGSGKKYK+C Sbjct: 878 KVGRNDPCPCGSGKKYKQCH 897
>PF05272#Virulence-associated E family protein Length = 892 Score = 31.2 bits (70), Expect = 0.009 Identities = 39/225 (17%), Positives = 71/225 (31%), Gaps = 45/225 (20%) Query: 211 IIREGMKV----VIAGRPNAGKSSLLNALAGKESAIVTEI-AGTTRDVLREHIHLDGMPL 265 ++ G K V+ G GKS+L+N L G + T GT +D + + G+ Sbjct: 588 VMEPGCKFDYSVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKD---SYEQIAGIVA 644 Query: 266 H-IIDTAGLRDTADTVEKIGIERAWDEIR------------------TADRVLFMVDGTT 306 + + + R K D R T ++ ++ D T Sbjct: 645 YELSEMTAFRRADAEAVKAFFSSRKDRYRGAYGRYVQDHPRQVVIWCTTNKRQYLFDITG 704 Query: 307 TPAVDPHEIWPDFIDRLPNNLGVTVVRNK--AD-----LTGEDLAITTEAGHSVYRISAK 359 WP + N + + R + A+ L GE + E +R + Sbjct: 705 N-----RRFWPVLVPGRANLVWLQKFRGQLFAEALHLYLAGERYFPSPEDEEIYFRPEQE 759 Query: 360 TGLGVDDLKQHLKSLMGYQSNLEG------GFIARRRHLEALDLA 398 L ++ L +L+ + G+ + DL Sbjct: 760 LRLVETGVQGRLWALLTREGAPAAEGAAQKGYSVNTTFVTIADLV 804
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 621 bits (1604), Expect = 0.0 Identities = 279/552 (50%), Positives = 379/552 (68%), Gaps = 21/552 (3%) Query: 1 MESQRNILLIGLLFVSFLLWQQWQADQAPQPVAAAQTQSSIPASTVADSHSSDVPDADSA 60 M+SQRN+L+I LLFVSF++WQ W+ D+ PQP A TQ++ A+ AD Sbjct: 1 MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAAG---------SAADQG 51 Query: 61 VPEAITASKELITVFTDQLEIKIDPVGGDIVYSALLSHKLEENGDDPFVLLEQTNDIYYI 120 VP + +LI+V TD L++ I+ GGD+ + L ++ E N PF LLE + Y Sbjct: 52 VPASGQG--KLISVKTDVLDLTINTRGGDVEQALLPAYPKELNSTQPFQLLETSPQFIYQ 109 Query: 121 AQSGLIGRDGIDSSVKG-RAHFDSASREYKLADGQDTLSVPLTYVSDKGVTYTKSFVFTR 179 AQSGL GRDG D+ G R ++ Y LA+GQ+ L VP+TY G T+TK+FV R Sbjct: 110 AQSGLTGRDGPDNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYTDAAGNTFTKTFVLKR 169 Query: 180 GKYNIAVDYKINNTSDASLQVQMYGQIKHSIKK------SESSMMMPTYLGGAFSTDDIR 233 G Y + V+Y + N + L++ +GQ+K SI S+ + T+ G A+ST D + Sbjct: 170 GDYAVNVNYNVQNAGEKPLEISSFGQLKQSITLPPHLDTGSSNFALHTFRGAAYSTPDEK 229 Query: 234 YEKYSFDDMADK-NLDDSTLGGWVAMLQHYFVSAWVPPATEKNIIFSS-MKNGLANIGFR 291 YEKY FD +AD NL+ S+ GGWVAMLQ YF +AW+P N +++ + NG+A IG++ Sbjct: 230 YEKYKFDTIADNENLNISSKGGWVAMLQQYFATAWIPHNDGTNNFYTANLGNGIAAIGYK 289 Query: 292 GELHDIAPGSEQVIKSEFYVGPKDQKALSVLSPSLNLVVDYGFLWWLAVPIYKLLMFFHS 351 + + PG + S +VGP+ Q ++ ++P L+L VDYG+LW+++ P++KLL + HS Sbjct: 290 SQPVLVQPGQTGAMNSTLWVGPEIQDKMAAVAPHLDLTVDYGWLWFISQPLFKLLKWIHS 349 Query: 352 IVGNWGFAIILITLTVRGLLYPLTKAQYTSMAKMRNLQPKLAELKERFGDDRQKMGQAMM 411 VGNWGF+II+IT VRG++YPLTKAQYTSMAKMR LQPK+ ++ER GDD+Q++ Q MM Sbjct: 350 FVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRISQEMM 409 Query: 412 ELYKKEKVNPMGGCLPILLQMPIFIALYWVLLESVELRHAPFMLWITDLSVQDPYYVLPI 471 LYK EKVNP+GGC P+L+QMPIF+ALY++L+ SVELR APF LWI DLS QDPYY+LPI Sbjct: 410 ALYKAEKVNPLGGCFPLLIQMPIFLALYYMLMGSVELRQAPFALWIHDLSAQDPYYILPI 469 Query: 472 LMGISMFVMQKMQPMAPTMDPMQVKMMQWMPVIFTVFFLWFPAGLVLYWLVGNLVAITQQ 531 LMG++MF +QKM P DPMQ K+M +MPVIFTVFFLWFP+GLVLY++V NLV I QQ Sbjct: 470 LMGVTMFFIQKMSP-TTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQ 528 Query: 532 KIIYAGLEKKGL 543 ++IY GLEK+GL Sbjct: 529 QLIYRGLEKRGL 540