>TACYTOLYSIN#Bacterial thiol-activated pore-forming cytolysin

		           signature.

		          Length = 574

		

		 Score =  889 bits (2299), Expect = 0.0

		 Identities = 566/574 (98%), Positives = 570/574 (99%)

		

		Query: 1   MKDMSNKKTFKKYSRVAGLLTAALIIGNLVTANAESNKQNTASTETTTTNEQPKPESSEL 60

		           MKDMSNKK FKKYSRVAGLLTAALI+GNLVTANA+SNKQNTA+TETTTTNEQPKPESSEL

		Sbjct: 1   MKDMSNKKIFKKYSRVAGLLTAALIVGNLVTANADSNKQNTANTETTTTNEQPKPESSEL 60

		

		Query: 61  TTEKAGQKTDDMLNSNDMIKLAPKEMPLESAEKEEKKSEDKKKSEEDHTEEINDKIYSLN 120

		           TTEKAGQK DDMLNSNDMIKLAPKEMPLESAEKEEKKSED KKSEEDHTEEINDKIYSLN

		Sbjct: 61  TTEKAGQKMDDMLNSNDMIKLAPKEMPLESAEKEEKKSEDNKKSEEDHTEEINDKIYSLN 120

		

		Query: 121 YNELEVLAKNGETIENFVPKEGVKKADKFIVIERKKKNINTTPVDISIIDSVTDRTYPAA 180

		           YNELEVLAKNGETIENFVPKEGVKKADKFIVIERKKKNINTTPVDISIIDSVTDRTYPAA

		Sbjct: 121 YNELEVLAKNGETIENFVPKEGVKKADKFIVIERKKKNINTTPVDISIIDSVTDRTYPAA 180

		

		Query: 181 LQLANKGFTENKPDAVVTKRNPQKIHIDLPGMGDKATVEVNDPTYANVSTAIDNLVNQWH 240

		           LQLANKGFTENKPDAVVTKRNPQKIHIDLPGMGDKATVEVNDPTYANVSTAIDNLVNQWH

		Sbjct: 181 LQLANKGFTENKPDAVVTKRNPQKIHIDLPGMGDKATVEVNDPTYANVSTAIDNLVNQWH 240

		

		Query: 241 DNYSGGNTLPARTQYTESMVYSKSQIEAALNVNSKILDGTLGIDFKSISKGEKKVMIAAY 300

		           DNYSGGNTLPARTQYTESMVYSKSQIEAALNVNSKILDGTLGIDFKSISKGEKKVMIAAY

		Sbjct: 241 DNYSGGNTLPARTQYTESMVYSKSQIEAALNVNSKILDGTLGIDFKSISKGEKKVMIAAY 300

		

		Query: 301 KQIFYTVSANLPNNPADVFDKSVTFKELQRKGVSNEAPPLFVSNVAYGRTVFVKLETSSK 360

		           KQIFYTVSANLPNNPADVFDKSVT KELQRKGVSNEAPPLFVSNVAYGRTVFVKLETSSK

		Sbjct: 301 KQIFYTVSANLPNNPADVFDKSVTLKELQRKGVSNEAPPLFVSNVAYGRTVFVKLETSSK 360

		

		Query: 361 SNDVEAAFSAALKGTDVKTNGKYSDILENSSFTAVVLGGDAAEHNKVVTKDFDVIRNVIK 420

		           SNDVEAAFSAALKGTDVKTNGKYSDILENSSFTAVVLGGDAAEHNKVVTKDFDVIRNVIK

		Sbjct: 361 SNDVEAAFSAALKGTDVKTNGKYSDILENSSFTAVVLGGDAAEHNKVVTKDFDVIRNVIK 420

		

		Query: 421 DNATFSRKNPAYPISYTSVFLKNNKIAGVNNRTEYVETTSTEYTSGKINLSHQGAYVAQY 480

		           DNATFSRKNPAYPISYTSVFLKNNKIAGVNNR+EYVETTSTEYTSGKINLSHQGAYVAQY

		Sbjct: 421 DNATFSRKNPAYPISYTSVFLKNNKIAGVNNRSEYVETTSTEYTSGKINLSHQGAYVAQY 480

		

		Query: 481 EILWDEINYDDKGKEVITKRRWDNNWYSKTSPFSTVIPLGANSRNIRIMARECTGLAWEW 540

		           EILWDEINYDDKGKEVITKRRWDNNWYSKTSPFSTVIPLGANSRNIRIMARECTGLAWEW

		Sbjct: 481 EILWDEINYDDKGKEVITKRRWDNNWYSKTSPFSTVIPLGANSRNIRIMARECTGLAWEW 540

		

		Query: 541 WRKVIDERDVKLSKEINVNISGSTLSPYGSITYK 574

		           WRKVIDERDVKLSKEINVNISGSTLSPYGSITYK

		Sbjct: 541 WRKVIDERDVKLSKEINVNISGSTLSPYGSITYK 574

		

		

		>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature.

		          Length = 1104

		

		 Score = 29.3 bits (65), Expect = 0.035

		 Identities = 16/72 (22%), Positives = 32/72 (44%), Gaps = 2/72 (2%)

		

		Query: 123 TSDVVILADGVIEIIDLKYGKGMPVSANQNPQMGLYALGAYASYDMV--YDFDRIKMTII 180

		           +  + ++ D  +E+I+          ANQ  +  +   G  +  D    Y FD  K   +

		Sbjct: 850 SKKIKVVEDKPVEVINESEPNNDFEKANQIAKSNMLVKGTLSEEDYSDKYYFDVAKKGNV 909

		

		Query: 181 QPRLDSVSSVDI 192

		           +  L++++SV I

		Sbjct: 910 KITLNNLNSVGI 921

		

		

		>PF07212#Hyaluronoglucosaminidase

		          Length = 336

		

		 Score =  554 bits (1429), Expect = 0.0

		 Identities = 255/334 (76%), Positives = 288/334 (86%), Gaps = 2/334 (0%)

		

		Query: 1   MTETIPLRVQFKRMTAEEWARSTVILLEGEIGLETDTGYAKFGDGKNRFSKLKYLNKPDL 60

		           MTETIPLRVQFKRMTAEEW RS VILLE EIG ETDTGYAKFGDGKN+FSKLKYLNKPDL

		Sbjct: 1   MTETIPLRVQFKRMTAEEWTRSDVILLESEIGFETDTGYAKFGDGKNQFSKLKYLNKPDL 60

		

		Query: 61  DAFAQKKETDNKIAKLESIKADKDTVYLKAESKIELDKKLSLAGGIVTGQLRLKPN-SGI 119

		            AFAQK+ET++KI KLES KADK+ VYLKAESKIELDKKL+L GG++TGQL+ KPN SGI

		Sbjct: 61  GAFAQKEETNSKITKLESSKADKNAVYLKAESKIELDKKLNLKGGVMTGQLQFKPNKSGI 120

		

		Query: 120 EKSSSTGGAINIDMSKSKGAAMVMYTNKDTTDGPLMILRSNKDTFDQSVQFVDYRGKTNA 179

		           + SSS GGAINIDMSKS+GA +V+Y+N DT+DGPLM LR+ K+TF+QS  FVDY GKTNA

		Sbjct: 121 KPSSSVGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLRTGKETFNQSALFVDYSGKTNA 180

		

		Query: 180 VNIVMRQPPTPNFSSALNITSANEGGSAMQIRGVEKALGTLKITHENPSVDKEYDKNAAA 239

		           VNI MRQP TPNFSSALNITS NE GSAMQIRGVEKALGTLKITHENP+V+  YD+NAAA

		Sbjct: 181 VNIAMRQPTTPNFSSALNITSGNENGSAMQIRGVEKALGTLKITHENPNVEANYDENAAA 240

		

		Query: 240 LSIDIVKKKKGGGDGTAAQGIFINSSSGTTGKLLRIRNKNEDKFYVNPDGGFHSYADSIV 299

		           LSIDIVKK+K GG GTAAQGI+INS+SGTTGKLLRIRN  +DKFYV  DGGF++   S +

		Sbjct: 241 LSIDIVKKQK-GGKGTAAQGIYINSTSGTTGKLLRIRNLGDDKFYVKHDGGFYAKKTSQI 299

		

		Query: 300 DGNLTVKNPTSGKHAATKDYVDKKFDELKKLIQK 333

		           DGNL +KNPT+  HAATK YVD +  +LK L+  

		Sbjct: 300 DGNLKLKNPTADDHAATKAYVDSEVKKLKALLMD 333

		

		

		>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family

		           signature.

		          Length = 639

		

		 Score = 28.3 bits (63), Expect = 0.039

		 Identities = 29/130 (22%), Positives = 44/130 (33%), Gaps = 16/130 (12%)

		

		Query: 109 SAKMDFNSNATINFNSRDNALVRKDGT--HTAFVHFSNATPKGYTGSALY------ASIG 160

		           S   DF   A I     +  L +K GT     ++ F    P+ Y   A        A+I 

		Sbjct: 511 STPADFRMLAPIVL---EQVL-KKAGTELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIV 566

		

		Query: 161 ITSSGDGVNSASSGRFAGLRSFRYAT---GYNHTAAVDQTELYGDNVLIADDFSINRGFK 217

		            T   +     S G         Y +    + +  +V  TEL G +V   +     R   

		Sbjct: 567 DTQLKNNEVILS-GEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRPN 625

		

		Query: 218 FRPDKMEKVL 227

		            R DK+  + 

		Sbjct: 626 SRIDKVRYMF 635

		

		

		>SECA#SecA protein signature.

		          Length = 901

		

		 Score = 31.0 bits (70), Expect = 0.011

		 Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 1/68 (1%)

		

		Query: 165 VIKH-YEKLAKGKQAIVYTHSVEASHLVSDMFNQAGYQSQSVSGKTPKSEREEAMQAFRD 223

		           +I+   E+ AKG+  +V T S+E S LVS+   +AG +   ++ K   +E     QA   

		Sbjct: 438 IIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYP 497

		

		Query: 224 GKLRILVN 231

		             + I  N

		Sbjct: 498 AAVTIATN 505

		

		

		>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature.

		          Length = 1541

		

		 Score = 30.8 bits (69), Expect = 0.004

		 Identities = 23/164 (14%), Positives = 56/164 (34%), Gaps = 11/164 (6%)

		

		Query: 8    EQSGAQEEAKEQTFDDILSDPKKQAEFDKRVAKAIDTARN-KWVAETEEKENEAK----- 61

		            E +    E  ++   ++ ++ +   E  +  ++  +T         T EKE +AK     

		Sbjct: 1060 ETTAQNREVAKEAKSNVKANTQ-TNEVAQSGSETKETQTTETKETATVEKEEKAKVETEK 1118

		

		Query: 62   --RLAKMNAEQKAQHEKAKLEARIAELEAER--TLSEMKSAARTMLSEANINISDALLSQ 117

		               + K+ ++   + E+++     AE   E   T++  +  ++T  +      +    S 

		Sbjct: 1119 TQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSN 1178

		

		Query: 118  LVSTTDADKTKNAVEAFSEAFSEAIEKEVKERLKSPTPKKSNGN 161

		            +        T N   +  E          +  + S +  K    

		Sbjct: 1179 VEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNR 1222

		

		

		>FLGFLGJ#Flagellar protein FlgJ signature.

		          Length = 313

		

		 Score = 37.4 bits (86), Expect = 3e-04

		 Identities = 32/139 (23%), Positives = 57/139 (41%), Gaps = 9/139 (6%)

		

		Query: 294 VFSQLYLESFWGDTPVGRAD----NNWGGI----TWTGATTRPSGINVSQGQSRAEGGYY 345

		           + +Q  LES WG   + R +     N  G+     W G  T  +      G+++     +

		Sbjct: 174 ILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKF 233

		

		Query: 346 NHYASVDDYLKDYAYLLAEQGIY-AVKGKLTIDEYTRGLFRVGGATYDYAAAGYDHYAPL 404

		             Y+S  + L DY  LL     Y AV    + ++  + L   G AT  + A    +    

		Sbjct: 234 RVYSSYLEALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQ 293

		

		Query: 405 MRDIRAGINRNNNGAMDNV 423

		           M+ I   +++  +  +DN+

		Sbjct: 294 MKSISDKVSKTYSMNIDNL 312

		

		

		>FRAGILYSIN#Fragilysin metallopeptidase (M10C) enterotoxin

		           signature.

		          Length = 405

		

		 Score = 28.9 bits (64), Expect = 0.007

		 Identities = 15/63 (23%), Positives = 25/63 (39%), Gaps = 5/63 (7%)

		

		Query: 25  VSAPVKHVLDNNKKAMEALESAIVKISDD-----LKDNNFKWTESKNHRDRLQKVQDQHE 79

		           + APV   +D    +   L + +  +SD      LKDN F      +   R +   D   

		Sbjct: 38  IDAPVTASIDLQSVSYTDLATQLNDVSDFGKMIILKDNGFNRQVHVSMDKRTKIQLDNEN 97

		

		Query: 80  IRI 82

		           +R+

		Sbjct: 98  VRL 100

		

		

		>UREASE#Urea amidohydrolase (urease) protein signature.

		          Length = 570

		

		 Score = 27.8 bits (62), Expect = 0.009

		 Identities = 11/54 (20%), Positives = 21/54 (38%), Gaps = 5/54 (9%)

		

		Query: 46  VARNAVEAVEQIAYDKDIK---GIEKLTEAKIAVRDELSKHNVYLSDK--QMEV 94

		              ++V  V Q + D  +    G+ K   A    R  + K ++  +     +EV

		Sbjct: 486 RTNSSVTFVSQASLDAGLAGRLGVAKELVAVQNTRGGIGKASMIHNSLTPHIEV 539

		

		

		>BACTRLTOXIN#Bacterial toxin signature.

		          Length = 266

		

		 Score =  277 bits (711), Expect = 1e-96

		 Identities = 114/257 (44%), Positives = 161/257 (62%), Gaps = 19/257 (7%)

		

		Query: 11  MVFFVLVTFLGLTISQEVFA--QQDPDPSQLHRSS-LVKNLQNIYFLYEGDPVTHENVKS 67

		           ++ F L+    +  +  V A  Q DP P  LH+SS     + N+ +LY+   V+   VKS

		Sbjct: 11  ILIFALIL---VISTPNVLAESQPDPMPDDLHKSSEFTGTMGNMKYLYDDHYVSATKVKS 67

		

		Query: 68  VDQLLSHDLIYNVSGP---NYDKLKTELKNQEMATLFKDKNIDIYGVEYYHLCYLCE--- 121

		           VD+ L+HDLIYN+S     NYDK+KTEL N+++A  +KD+ +D+YG  YY  CY      

		Sbjct: 68  VDKFLAHDLIYNISDKKLKNYDKVKTELLNEDLAKKYKDEVVDVYGSNYYVNCYFSSKDN 127

		

		Query: 122 ---NAERSACIYGGVTNHEGNHLEIP--KKIVVKVSIDGIQSLSFDIETNKKMVTAQELD 176

		                    C+YGG+T HEGNH +    + ++V+V  +   ++SF+++T+KK VTAQELD

		Sbjct: 128 VGKVTGGKTCMYGGITKHEGNHFDNGNLQNVLVRVYENKRNTISFEVQTDKKSVTAQELD 187

		

		Query: 177 YKVRKYLTDNKQLYTNGPSKYETGYIKFIPKNKESFWFDFFPEP--EFTQSKYLMIYKDN 234

		            K R +L + K LY    S YETGYIKFI  N  +FW+D  P P  +F QSKYLM+Y DN

		Sbjct: 188 IKARNFLINKKNLYEFNSSPYETGYIKFIENNGNTFWYDMMPAPGDKFDQSKYLMMYNDN 247

		

		Query: 235 ETLDSNTSQIEVYLTTK 251

		           +T+DS + +IEV+LTTK

		Sbjct: 248 KTVDSKSVKIEVHLTTK 264

		

		

		>PF03309#Bvg accessory factor

		          Length = 271

		

		 Score = 29.7 bits (67), Expect = 0.012

		 Identities = 13/65 (20%), Positives = 23/65 (35%), Gaps = 7/65 (10%)

		

		Query: 18 LLCIDIGGTSLKFALCHN----GQLSQQSSFPT--PSSLEKFYQLLDQEVARYSAYHFSG 71

		          LL ID+  T     L        ++ QQ    T    + ++    +D  +    A   +G

		Sbjct: 2  LLAIDVRNTHTVVGLISGSGDHAKVVQQWRIRTEPEVTADELALTIDG-LIGDDAERLTG 60

		

		Query: 72 IAISS 76

		           +  S

		Sbjct: 61 ASGLS 65

		

		

		>PF06580#Sensor histidine kinase

		          Length = 349

		

		 Score =  180 bits (459), Expect = 6e-54

		 Identities = 71/324 (21%), Positives = 132/324 (40%), Gaps = 34/324 (10%)

		

		Query: 251 LSKAYRMQYNRSGDLLAYVAVRKSYLLAEAVRTVFVYGLVSLLLAWLLLQLL-FRVFRNY 309

		           L+ AYR    R G  L     +    +  A   + +   V+    W LL  +  +     

		Sbjct: 55  LTHAYRSFIKRQG-WLKLNMGQIILRVLPACVVIGMVWFVANTSIWRLLAFINTKPVAFT 113

		

		Query: 310 IQQVSEITDTVEMVAAGDLSLTIDNSHMELELYHISEAINQMLASIKAYIDEVYVLEVEQ 369

		           +     I   V +V           + M   LY      +      +A ID+   +    

		Sbjct: 114 LPLALSIIFNVVVV-----------TFMWSLLYF---GWHFFKNYKQAEIDQWK-MASMA 158

		

		Query: 370 RDAQMRALQSQINPHFLYNTLEYIRMYALSCQQEELADVIYAFASLLRNNI--SQDKMTT 427

		           ++AQ+ AL++QINPHF++N L  IR   L     +  +++ + + L+R ++  S  +  +

		Sbjct: 159 QEAQLMALKAQINPHFMFNALNNIRALILE-DPTKAREMLTSLSELMRYSLRYSNARQVS 217

		

		Query: 428 LKEELAFCEKYIYLYQMRYPDSFAYHVKIDESIADLAIPKFVIQPLVENYFVHGIDYSRH 487

		           L +EL   + Y+ L  +++ D   +  +I+ +I D+ +P  ++Q LVEN   HGI     

		Sbjct: 218 LADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQ 277

		

		Query: 488 DNALSIKALDETDHLLIQVLDNGRGISQERLADMEKRLQEHQTTGNISIGLQNVYLRLFH 547

		              + +K   +   + ++V + G              L    T  +   GLQNV  RL  

		Sbjct: 278 GGKILLKGTKDNGTVTLEVENTG-------------SLALKNTKESTGTGLQNVRERLQM 324

		

		Query: 548 HFRDRVSWSMAKEPNGGFIIQIRI 571

		            +       ++++  G     + I

		Sbjct: 325 LYGTEAQIKLSEKQ-GKVNAMVLI 347

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 84.9 bits (210), Expect = 1e-19

		 Identities = 31/133 (23%), Positives = 50/133 (37%), Gaps = 6/133 (4%)

		

		Query: 4   KVLLVDDEYMILQGLTMIIDWQALGFEVVQTARSGKEALAYLTQYPVDVMISDVTMPGMT 63

		            +L+ DD+  I   L   +     G++V     +      ++     D++++DV MP   

		Sbjct: 5   TILVADDDAAIRTVLNQAL--SRAGYDVR-ITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61

		

		Query: 64  GLDLIEAAKTYHPQLQTLILSGYQEFSYVQKAMELETKGYLLKPVDKAELQAKMKQFKDC 123

		             DL+   K   P L  L++S    F    KA E     YL KP D   L   +      

		Sbjct: 62  AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFD---LTELIGIIGRA 118

		

		Query: 124 LDAQQAESIRQEA 136

		           L   +    + E 

		Sbjct: 119 LAEPKRRPSKLED 131

		

		

		>ARGREPRESSOR#Bacterial arginine repressor signature.

		          Length = 149

		

		 Score = 27.1 bits (60), Expect = 0.046

		 Identities = 8/24 (33%), Positives = 15/24 (62%)

		

		Query: 151 GELAKILKQNGVNIGQNKLFQWLR 174

		            EL  ILK++G N+ Q  + + ++

		Sbjct: 23  DELVDILKKDGYNVTQATVSRDIK 46

		

		

		>ANTHRAXTOXNA#Anthrax toxin LF subunit signature.

		          Length = 800

		

		 Score = 27.8 bits (61), Expect = 0.026

		 Identities = 23/89 (25%), Positives = 40/89 (44%), Gaps = 1/89 (1%)

		

		Query: 71  QAEAKVEKYKETIRRAMELSQKKKVDAGMFKVSLRKSKKVEILDETKIPLDYMQEKIEYK 130

		           +  A  E Y E+  +    ++K K +   FK S+    K E  +ET   +   Q+ ++  

		Sbjct: 30  EVNAMNEHYTESDIKRNHKTEKNKTEKEKFKDSINNLVKTEFTNETLDKIQQTQDLLKKI 89

		

		Query: 131 PMKS-EISKALKSGIDISGVELIETESLQ 158

		           P    EI   L   I  + ++L+E + LQ

		Sbjct: 90  PKDVLEIYSELGGEIYFTDIDLVEHKELQ 118

		

		

		>GPOSANCHOR#Gram-positive coccus surface protein anchor signature.

		          Length = 539

		

		 Score = 47.8 bits (113), Expect = 2e-07

		 Identities = 50/287 (17%), Positives = 97/287 (33%), Gaps = 29/287 (10%)

		

		Query: 454 LTKESDETKKLKKEQEGLVESNKQLRDSVREGVQERKKGLESVKESTAAHQKLADEIIKL 513

		            T +S + K L+ E+  L      L        +  +  +      +A  + L  E   L

		Sbjct: 136 STADSAKIKTLEAEKAALAARKADLE-------KALEGAMNFSTADSAKIKTLEAEKAAL 188

		

		Query: 514 AAKENKTAGEKRNLKNKIDELNGSIDGLNLAYDKNSNSLSHNADQIKSRISAMEAESTWQ 573

		            A++ +         N     +  I  L       +   +     ++  +      S   

		Sbjct: 189 EARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKA----DLEKALEGAMNFS--- 241

		

		Query: 574 TAQQNLLNIEQKRSEVSKKLAENAELRKKWNEEANVSDSVRKEKIAELTEEEAKLKNMQT 633

		               +   I+   +E +   A  AEL K   E A    +    KI  L  E+A L+  + 

		Sbjct: 242 --TADSAKIKTLEAEKAALEARQAELEKA-LEGAMNFSTADSAKIKTLEAEKAALEAEKA 298

		

		Query: 634 QLQEEYNKTSATQQAAADAMAAAEESGSARQVIAYENMSEAQRTAIDNMRTKYSELLETT 693

		            L+ +    +A +Q+    + A+ E  + +Q+ A     E Q    +  R      L+ +

		Sbjct: 299 DLEHQSQVLNANRQSLRRDLDASRE--AKKQLEAEHQKLEEQNKISEASRQSLRRDLDAS 356

		

		Query: 694 TSIFDAIE----------QKTALSVDQMNANLEKNRAATEQWATNLE 730

		                 +E          + +  S   +  +L+ +R A +Q    LE

		Sbjct: 357 REAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALE 403

		

		

		

		 Score = 30.8 bits (69), Expect = 0.032

		 Identities = 43/240 (17%), Positives = 77/240 (32%), Gaps = 33/240 (13%)

		

		Query: 454 LTKESDETKKLKKEQEGLVESNKQLRDSVREGVQERKKGLESVKESTAAHQKLADEIIKL 513

		            T +S + K L+ E+  L      L  ++   +         +K   A    L     +L

		Sbjct: 206 STADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAEL 265

		

		Query: 514 AAKENKTAGEKRNLKNKIDELNGSIDGL----------NLAYDKNSNSLSHNADQIKSRI 563

		                           KI  L      L          +   + N  SL  + D  +   

		Sbjct: 266 EKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAK 325

		

		Query: 564 SAMEAESTWQTAQQNLLNIEQKRSEVSKKLAENAELRK-------KWNEEANVSDSVR-- 614

		             +EAE   Q  ++     E  R  + + L  + E +K       K  E+  +S++ R  

		Sbjct: 326 KQLEAEH--QKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQS 383

		

		Query: 615 -----------KEKI-AELTEEEAKLKNMQTQLQEEYNKTSATQQAAADAMAAAEESGSA 662

		                      K+++   L E  +KL  ++   +E       T++  A+  A  E    A

		Sbjct: 384 LRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKA 443

		

		

		>PF07212#Hyaluronoglucosaminidase

		          Length = 336

		

		 Score =  507 bits (1307), Expect = 0.0

		 Identities = 260/343 (75%), Positives = 287/343 (83%), Gaps = 15/343 (4%)

		

		Query: 1   MSENIPLRVQFKRMKAAEWARSDVILLESEIGFETDTGFARAGDGHNRFSDLGYISPLDY 60

		           M+E IPLRVQFKRM A EW RSDVILLESEIGFETDTG+A+ GDG N+FS L Y+     

		Sbjct: 1   MTETIPLRVQFKRMTAEEWTRSDVILLESEIGFETDTGYAKFGDGKNQFSKLKYL----- 55

		

		Query: 61  NLLTNKPNIDGLATKVETAQKLQQ----KADKETVYTKAESKQELDKKLNLKGGVMTGQL 116

		               NKP++   A K ET  K+ +    KADK  VY KAESK ELDKKLNLKGGVMTGQL

		Sbjct: 56  ----NKPDLGAFAQKEETNSKITKLESSKADKNAVYLKAESKIELDKKLNLKGGVMTGQL 111

		

		Query: 117 KFKPAAT-VAYSSSTGGAVNIDLSSSRGAGVVVYSDNDTSDGPLMSLRTGKETFNQSALF 175

		           +FKP  + +  SSS GGA+NID+S S GAGVVVYS+NDTSDGPLMSLRTGKETFNQSALF

		Sbjct: 112 QFKPNKSGIKPSSSVGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLRTGKETFNQSALF 171

		

		Query: 176 VDYKGTTNAVNIAMRQPTTPNFSSALNITSGNENGSAMQLRGSEKALGTLKITHENPSIG 235

		           VDY G TNAVNIAMRQPTTPNFSSALNITSGNENGSAMQ+RG EKALGTLKITHENP++ 

		Sbjct: 172 VDYSGKTNAVNIAMRQPTTPNFSSALNITSGNENGSAMQIRGVEKALGTLKITHENPNVE 231

		

		Query: 236 ADYDKNAAALSIDIVKKTNGA-GTAAQGIYINSTSGTTGKLLRIRNLSDDKFYVKSDGGF 294

		           A+YD+NAAALSIDIVKK  G  GTAAQGIYINSTSGTTGKLLRIRNL DDKFYVK DGGF

		Sbjct: 232 ANYDENAAALSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIRNLGDDKFYVKHDGGF 291

		

		Query: 295 YAKETSQIDGNLKLKDPTANDHAATKAYVDKAISELKKLILKK 337

		           YAK+TSQIDGNLKLK+PTA+DHAATKAYVD  + +LK L++ K

		Sbjct: 292 YAKKTSQIDGNLKLKNPTADDHAATKAYVDSEVKKLKALLMDK 334

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 34.4 bits (79), Expect = 0.001

		 Identities = 17/173 (9%), Positives = 44/173 (25%), Gaps = 7/173 (4%)

		

		Query: 117 TEIVNSARGVATRISEDTDKKLALINDTIDGIRREYRDADRKLSASYQAGIEGLKATMAN 176

		               +        +    +     +++                  + +   E        

		Sbjct: 155 ILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRA 214

		

		Query: 177 DKIGLQAEIKA--SAQGLSQKYDNELRQLSAKITTTSSGTTEAYESKLAGLRAEFTRSNQ 234

		           +++ + A I    +   + +   ++   L  K    +       E+K      E  R  +

		Sbjct: 215 ERLTVLARINRYENLSRVEKSRLDDFSSLLHK-QAIAKHAVLEQENKYVEAVNEL-RVYK 272

		

		Query: 235 GTRTELESQISGLRAVQQTTASQISQEIRNREGAVSRVQQGLDSYQRRLQSAE 287

		               ++ES+I   +   Q        EI      + +    +      L   E

		Sbjct: 273 SQLEQIESEILSAKEEYQLVTQLFKNEIL---DKLRQTTDNIGLLTLELAKNE 322

		

		

		>FLGFLGJ#Flagellar protein FlgJ signature.

		          Length = 313

		

		 Score = 87.1 bits (215), Expect = 2e-21

		 Identities = 43/125 (34%), Positives = 62/125 (49%), Gaps = 8/125 (6%)

		

		Query: 23  SLTAAQAILESGWGKHA-------PHNALFGIKADASWTGKSFDTKTQEEYQPGIVTDIV 75

		            L  AQA LESGWG+         P   LFG+KA  +W G   +  T E Y+ G    + 

		Sbjct: 172 HLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTE-YENGEAKKVK 230

		

		Query: 76  DRFRAYDSWTDSIIDHGKFLNDNPRYKAVIGETDYKKACYAIKAAGYATASSYVELLIQL 135

		            +FR Y S+ +++ D+   L  NPRY AV      ++   A++ AGYAT   Y   L  +

		Sbjct: 231 AKFRVYSSYLEALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNM 290

		

		Query: 136 IEEND 140

		           I++  

		Sbjct: 291 IQQMK 295

		

		

		>BACTRLTOXIN#Bacterial toxin signature.

		          Length = 266

		

		 Score = 44.9 bits (106), Expect = 6e-08

		 Identities = 44/222 (19%), Positives = 85/222 (38%), Gaps = 36/222 (16%)

		

		Query: 6   LKEIYN-KEIIEKNNISINAKQGTQLIFNTDENTTVWNDNTFKKVISSNLSPSQERMFNV 64

		           +K +Y+   +      S++      LI+N  +      D    KV +  L+    + +  

		Sbjct: 51  MKYLYDDHYVSATKVKSVDKFLAHDLIYNISDKKLKNYD----KVKTELLNEDLAKKYK- 105

		

		Query: 65  GDHVNIFAIVKSYHVVCKEQFNYSD---------GGIIKTSDVKPEE---KAIYINIFGE 112

		            + V+++      +     + N            GGI K      +    + + + ++  

		Sbjct: 106 DEVVDVYGSNYYVNCYFSSKDNVGKVTGGKTCMYGGITKHEGNHFDNGNLQNVLVRVYEN 165

		

		Query: 113 KELRTLTAKDKITFKNNIVTLQEIDVRLRKSLMGDSKIKLYEYD-SLYKKGFWDIHYKDG 171

		           K     T   ++      VT QE+D++ R  L+  +K  LYE++ S Y+ G+      +G

		Sbjct: 166 KRN---TISFEVQTDKKSVTAQELDIKARNFLI--NKKNLYEFNSSPYETGYIKFIENNG 220

		

		Query: 172 GIRHTNLFTYPD-----------YTDNETIDMSKVSHFDVHL 202

		                ++   P            Y DN+T+D SK    +VHL

		Sbjct: 221 NTFWYDMMPAPGDKFDQSKYLMMYNDNKTVD-SKSVKIEVHL 261

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 92.6 bits (230), Expect = 1e-23

		 Identities = 42/163 (25%), Positives = 73/163 (44%), Gaps = 12/163 (7%)

		

		Query: 2   LIVEDEYLVRQGIRSLVDFSQFKIDRVNEAENGQLAWDLFQKEPYDIVLTDINMPKLNGI 61

		           L+ +D+  +R  +   +  + +    V    N    W        D+V+TD+ MP  N  

		Sbjct: 7   LVADDDAAIRTVLNQALSRAGY---DVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63

		

		Query: 62  QLAELIKQESPQTHLVFLTGYDDFNYALSALKLGADDYLLKPFSKADVEDMLGKLQQKLD 121

		            L   IK+  P   ++ ++  + F  A+ A + GA DYL KPF   D+ +++G + + L 

		Sbjct: 64  DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPF---DLTELIGIIGRALA 120

		

		Query: 122 LSKKTETIQELVEQPQKEVSAIAMAIHE------RLADSDLTL 158

		             K+  +  E   Q    +   + A+ E      RL  +DLTL

		Sbjct: 121 EPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTL 163

		

		

		>PF06580#Sensor histidine kinase

		          Length = 349

		

		 Score =  183 bits (466), Expect = 7e-55

		 Identities = 57/203 (28%), Positives = 101/203 (49%), Gaps = 10/203 (4%)

		

		Query: 362 EKAIGQYRLQALASQINPHFLYNTLDTIIWMAEFNDSKRVVEVTKSLAKYFRLALNQGN- 420

		                + +L AL +QINPHF++N L+ I  +    D  +  E+  SL++  R +L   N 

		Sbjct: 155 ASMAQEAQLMALKAQINPHFMFNALNNIRALIL-EDPTKAREMLTSLSELMRYSLRYSNA 213

		

		Query: 421 EYIRLADELDHVSQYLFIQKQRYGDKLSYEVQGLDVYADFVIPKLILQPLVENAIYHGIK 480

		             + LADEL  V  YL +   ++ D+L +E Q      D  +P +++Q LVEN I HGI 

		Sbjct: 214 RQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGIA 273

		

		Query: 481 EVDRKGMIKVTVSDTAQHLMLTVWDNGKGIEDSSLTNSQSLLARGGVGLKNVDQRLKLHY 540

		           ++ + G I +  +     + L V + G     ++  ++       G GL+NV +RL++ Y

		Sbjct: 274 QLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKEST-------GTGLQNVRERLQMLY 326

		

		Query: 541 GEGYHMTIHSQSDQFTEIQLSLP 563

		           G    + +  +  +   + + +P

		Sbjct: 327 GTEAQIKLSEKQGKVNAM-VLIP 348

		

		

		>ARGREPRESSOR#Bacterial arginine repressor signature.

		          Length = 149

		

		 Score =  123 bits (310), Expect = 7e-39

		 Identities = 60/146 (41%), Positives = 92/146 (63%), Gaps = 2/146 (1%)

		

		Query: 1   MNKKETRHRLIRSLISETTIHTQQELQERLQKNGITITQATLSRDMKELNLVKVTSGNDT 60

		           MNK + RH  IR +I+   I TQ EL + L+K+G  +TQAT+SRD+KEL+LVKV + N +

		Sbjct: 1   MNKGQ-RHIKIREIITANEIETQDELVDILKKDGYNVTQATVSRDIKELHLVKVPTNNGS 59

		

		Query: 61  HYEALAISQTRWEH-RLRFYMEDALVMLKIVQHQIILKTLPGLAQSFGSILDAMQIPEIV 119

		           +  +L   Q      +L+  + DA V +    H I+LKT+PG AQ+ G+++D +   EI+

		Sbjct: 60  YKYSLPADQRFNPLSKLKRSLMDAFVKIDSASHLIVLKTMPGNAQAIGALMDNLDWEEIM 119

		

		Query: 120 ATVCGDDTCLIVCEDNEQAKACYETL 145

		            T+CGDDT LI+C  ++  K   + +

		Sbjct: 120 GTICGDDTILIICRTHDDTKVVQKKI 145

		

		

		>ARGDEIMINASE#Bacterial arginine deiminase signature.

		          Length = 409

		

		 Score =  579 bits (1493), Expect = 0.0

		 Identities = 192/410 (46%), Positives = 277/410 (67%), Gaps = 9/410 (2%)

		

		Query: 5   TPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDIPFLEDAQKEHDAFAQALRDE 64

		            PI+++SEIG+LKKVLLHRPG+E+ENL P  ++  LFDDIP+LE A++EH+ FA  L++ 

		Sbjct: 6   NPINIFSEIGRLKKVLLHRPGEELENLTPFIMKNFLFDDIPYLEVARQEHEVFASILKNN 65

		

		Query: 65  GIEVLYLETLAAESLVTP-EIREAFIDEYLSEANIRGRATKKAIRELLMAIEDNQELIEK 123

		            +E+ Y+E L +E LV+   +   FI +++ EA I+   T   +++   ++     +I K

		Sbjct: 66  LVEIEYIEDLISEVLVSSVALENKFISQFILEAEIKTDFTINLLKDYFSSL-TIDNMISK 124

		

		Query: 124 TMAGVQKSELPEIPASEKGLTDLVESSYPFAIDPMPNLYFTRDPFATIGTGVSLNHMFSE 183

		            ++GV   EL    +S   L DLV  +  F IDPMPN+ FTRDPFA+IG GV++N MF++

		Sbjct: 125 MISGVVTEELKNYTSS---LDDLVNGANLFIIDPMPNVLFTRDPFASIGNGVTINKMFTK 181

		

		Query: 184 TRNRETLYGKYIFTHHPIYGGGKVPMVYDRNETTRIEGGDELVLSKDVLAVGISQRTDAA 243

		            R RET++ +YIF +HP+Y    VP+  +R E   +EGGDELVL+K +L +GIS+RT+A 

		Sbjct: 182 VRQRETIFAEYIFKYHPVYKE-NVPIWLNRWEEASLEGGDELVLNKGLLVIGISERTEAK 240

		

		Query: 244 SIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHLDTVFTMVDYDKFTIHPEIEGDLRVYSV 303

		           S+EKL +++FK    F  +LAF+   NR +MHLDTVFT +DY  FT     +    +Y +

		Sbjct: 241 SVEKLAISLFKNKTSFDTILAFQIPKNRSYMHLDTVFTQIDYSVFTSFTSDDMYFSIYVL 300

		

		Query: 304 TYDNE--ELHIVEEKGDLADLLAANLGVEKVDLIRCGGDNLVAAGREQWNDGSNTLTIAP 361

		           TY+    ++HI +EK  + D+L+  LG  K+D+I+C G +L+   REQWNDG+N L IAP

		Sbjct: 301 TYNPSSSKIHIKKEKARIKDVLSFYLG-RKIDIIKCAGGDLIHGAREQWNDGANVLAIAP 359

		

		Query: 362 GVVVVYNRNTITNAILESKGLKLIKIHGSELVRGRGGPRCMSMPFEREDI 411

		           G ++ Y+RN +TN + E  G+K+ +I  SEL RGRGGPRCMSMP  REDI

		Sbjct: 360 GEIIAYSRNHVTNKLFEENGIKVHRIPSSELSRGRGGPRCMSMPLIREDI 409

		

		

		>CARBMTKINASE#Bacterial carbamate kinase signature.

		          Length = 314

		

		 Score =  407 bits (1048), Expect = e-146

		 Identities = 141/315 (44%), Positives = 204/315 (64%), Gaps = 6/315 (1%)

		

		Query: 3   KQKIVVALGGNAIL--STDASAKAQQEALISTSKSLVKLIKEGHEVIVTHGNGPQVGNLL 60

		            +++V+ALGGNA+       S +   + +  T++ + ++I  G+EV++THGNGPQVG+LL

		Sbjct: 2   GKRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSLL 61

		

		Query: 61  LQQAAADSEKN-PAMPLDTCVAMTEGSIGFWLVNALDNELQAQGIQKEVAAVVTQVIVDA 119

		           L   A  +    PA P+D   AM++G IG+ +  AL NEL+ +G++K+V  ++TQ IVD 

		Sbjct: 62  LHMDAGQATYGIPAQPMDVAGAMSQGWIGYMIQQALKNELRKRGMEKKVVTIITQTIVDK 121

		

		Query: 120 KDPAFENPTKPIGPFLTEEDAKKQMAESGASFKEDAGRGWRKVVPSPKPVGIKEANVIRS 179

		            DPAF+NPTKP+GPF  EE AK+   E G   KED+GRGWR+VVPSP P G  EA  I+ 

		Sbjct: 122 NDPAFQNPTKPVGPFYDEETAKRLAREKGWIVKEDSGRGWRRVVPSPDPKGHVEAETIKK 181

		

		Query: 180 LVDSGVVVVSAGGGGVPVVEDATSKTLTGVEAVIDKDFASQTLSELVDADLFIVLTGVDN 239

		           LV+ GV+V+++GGGGVPV+ +     + GVEAVIDKD A + L+E V+AD+F++LT V+ 

		Sbjct: 182 LVERGVIVIASGGGGVPVILED--GEIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVNG 239

		

		Query: 240 VYVNFNKPDQTKLEEVTVSQMKEYITQDQFAPGSMLPKVEAAIAFVENKPNAKAIITSLE 299

		             + +    +  L EV V ++++Y  +  F  GSM PKV AAI F+E     +AII  LE

		Sbjct: 240 AALYYGTEKEQWLREVKVEELRKYYEEGHFKAGSMGPKVLAAIRFIEW-GGERAIIAHLE 298

		

		Query: 300 NIDNVLSANAGTQII 314

		                L    GTQ++

		Sbjct: 299 KAVEALEGKTGTQVL 313

		

		

		>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein

		           signature.

		          Length = 166

		

		 Score =  153 bits (388), Expect = 2e-50

		 Identities = 58/157 (36%), Positives = 94/157 (59%), Gaps = 2/157 (1%)

		

		Query: 5   IGLYTGSFDPVTNGHLDIVKRASGLFDQIYVGIFDNPTKKSYFKLEVRKAMLTQALADFT 64

		             +Y GSFDP+T GHLDI++R   LFDQ+YV +  NP K+  F ++ R   + +A+A   

		Sbjct: 2   NAIYPGSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPMFSVQERLEQIAKAIAHLP 61

		

		Query: 65  NVIVVTSHERLAIDVAKELRVTHLIRGLRNATDFEYEENLEYFNHLLAPNIETVYLISRN 124

		           N  V +  E L ++ A++ +   ++RGLR  +DFE E  +   N  LA ++ETV+L +  

		Sbjct: 62  NAQVDSF-EGLTVNYARQRQAGAILRGLRVLSDFELELQMANTNKTLASDLETVFLTTST 120

		

		Query: 125 KWQALSSSRVRELIHFQSSLEGLVPQSVIAQV-EKMN 160

		           ++  LSSS V+E+  F  ++E  VP  V A + ++ +

		Sbjct: 121 EYSFLSSSLVKEVARFGGNVEHFVPSHVAAALYDQFH 157

		

		

		>DNABINDINGHU#Prokaryotic integration host factor signature.

		          Length = 91

		

		 Score =  124 bits (312), Expect = 5e-41

		 Identities = 82/91 (90%), Positives = 87/91 (95%)

		

		Query: 1  MANKQDLIAKVAEATELTKKDSAAAVDAVFSTIEAFLAEGEKVQLIGFGNFEVRERAARK 60

		          MANKQDLIAKVAEATELTKKDSAAAVDAVFS + ++LA+GEKVQLIGFGNFEVRERAARK

		Sbjct: 1  MANKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARK 60

		

		Query: 61 GRNPQTGAEIEIAASKVPAFKAGKALKDAVK 91

		          GRNPQTG EI+I ASKVPAFKAGKALKDAVK

		Sbjct: 61 GRNPQTGEEIKIKASKVPAFKAGKALKDAVK 91

		

		

		>SACTRNSFRASE#Streptothricin acetyltransferase signature.

		          Length = 173

		

		 Score = 28.0 bits (62), Expect = 0.026

		 Identities = 13/37 (35%), Positives = 18/37 (48%)

		

		Query: 119 KSEETEDYITDYVEGLVAAGLGAYQEDNLHMKVKLRS 155

		           K  E +D    YVE    A    Y E+N   ++K+RS

		Sbjct: 48  KQYEDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRS 84

		

		

		>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family

		           signature.

		          Length = 1024

		

		 Score = 39.6 bits (92), Expect = 5e-05

		 Identities = 25/133 (18%), Positives = 59/133 (44%), Gaps = 7/133 (5%)

		

		Query: 503 LGASGQGLSSMLSSAWGNIQTVVSTAKNMITLAIDGIKL--VFSNLGNAGNILKGLLSAA 560

		            G    G +  +    G    ++ST +N +  A+  +K+  +     + GN+    L+ A

		Sbjct: 124 AGNILGGGAENIGDNLGKAGGILSTFQNFLGTALSSMKIDELIKKQKSGGNVSSSELAKA 183

		

		Query: 561 WSAMQNAVVIAKGIINSAISAIKTAFSSFGNLVSSVSGTIKSVIGSLKNAFYSLASIDLV 620

		              + N +V     +N+ +++     ++ G+++S+        +  + N   +L ++D +

		Sbjct: 184 SIELINQLVDTVASLNNNVNSFSQQLNTLGSVLSNTKH-----LNGVGNKLQNLPNLDNI 238

		

		Query: 621 GAGRAIMQGFLNG 633

		           GAG   + G L+ 

		Sbjct: 239 GAGLDTVSGILSA 251

		

		

		>PF07212#Hyaluronoglucosaminidase

		          Length = 336

		

		 Score =  511 bits (1318), Expect = 0.0

		 Identities = 242/358 (67%), Positives = 284/358 (79%), Gaps = 39/358 (10%)

		

		Query: 1   MSADEWARSDVILLEGEIGFETDTGYAKFGNGKSKFSALKYLTGPKGPKGDTGFQGKTGG 60

		           M+A+EW RSDVILLE EIGFETDTGYAKFG+GK++FS LKYL                  

		Sbjct: 14  MTAEEWTRSDVILLESEIGFETDTGYAKFGDGKNQFSKLKYL------------------ 55

		

		Query: 61  TGPRGPAGKPGTTDYNQLQNKPNLDAFARKQETDSKITELKSNKADKNAVYLKAESNAKL 120

		                              NKP+L AFA+K+ET+SKIT+L+S+KADKNAVYLKAES  +L

		Sbjct: 56  -------------------NKPDLGAFAQKEETNSKITKLESSKADKNAVYLKAESKIEL 96

		

		Query: 121 DEKLSLTGGIVTGQLQFKPN-SGIKPSSSVGGAINIDMSKSEGAAMVMYTNKDTTDGPLM 179

		           D+KL+L GG++TGQLQFKPN SGIKPSSSVGGAINIDMSKSEGA +V+Y+N DT+DGPLM

		Sbjct: 97  DKKLNLKGGVMTGQLQFKPNKSGIKPSSSVGGAINIDMSKSEGAGVVVYSNNDTSDGPLM 156

		

		Query: 180 ILRSDKDTFDQSAQFVDYSGKTNAVNIVMRQPSAPNFSSALNITSANEGGSAMQIRGVEK 239

		            LR+ K+TF+QSA FVDYSGKTNAVNI MRQP+ PNFSSALNITS NE GSAMQIRGVEK

		Sbjct: 157 SLRTGKETFNQSALFVDYSGKTNAVNIAMRQPTTPNFSSALNITSGNENGSAMQIRGVEK 216

		

		Query: 240 ALGTLKITHENPNVKANYDENAAALSIDIVKKTN-GEGTAAQGIYINSSTGTTGKMLRIR 298

		           ALGTLKITHENPNV+ANYDENAAALSIDIVKK   G+GTAAQGIYINS++GTTGK+LRIR

		Sbjct: 217 ALGTLKITHENPNVEANYDENAAALSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIR 276

		

		Query: 299 NKNEDKFYVGPDGGFHSGANSTVAGNLTVKDPTSGKHAATKDYVDEKIAELKKLILKK 356

		           N  +DKFYV  DGGF++   S + GNL +K+PT+  HAATK YVD ++ +LK L++ K

		Sbjct: 277 NLGDDKFYVKHDGGFYAKKTSQIDGNLKLKNPTADDHAATKAYVDSEVKKLKALLMDK 334

		

		

		>SECA#SecA protein signature.

		          Length = 901

		

		 Score = 31.0 bits (70), Expect = 0.011

		 Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 1/68 (1%)

		

		Query: 165 VIKH-YEKLAKGKQAIVYTHSVEASHLVSDMFNQAGYQSQSVSGKTPKSEREEAMQAFRD 223

		           +I+   E+ AKG+  +V T S+E S LVS+   +AG +   ++ K   +E     QA   

		Sbjct: 438 IIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYP 497

		

		Query: 224 GKLRILVN 231

		             + I  N

		Sbjct: 498 AAVTIATN 505

		

		

		>PF06580#Sensor histidine kinase

		          Length = 349

		

		 Score = 25.6 bits (56), Expect = 0.038

		 Identities = 7/45 (15%), Positives = 18/45 (40%)

		

		Query: 29  LFLAIAIFGMMVTVSYFSYRDARQYYEPQIYGLRTQLSMTQKQLK 73

		           +   + +   M ++ YF +   + Y + +I   +      + QL 

		Sbjct: 120 IIFNVVVVTFMWSLLYFGWHFFKNYKQAEIDQWKMASMAQEAQLM 164

		

		

		>PF07212#Hyaluronoglucosaminidase

		          Length = 336

		

		 Score =  495 bits (1275), Expect = e-179

		 Identities = 242/354 (68%), Positives = 275/354 (77%), Gaps = 35/354 (9%)

		

		Query: 1   MTTQGWESSSDILMEREIGIDMTTGYPKVGDGKNKFKDLKDLRGPMGPQGPTGERGPIGP 60

		           MT + W  S  IL+E EIG +  TGY K GDGKN+F  LK L                  

		Sbjct: 14  MTAEEWTRSDVILLESEIGFETDTGYAKFGDGKNQFSKLKYL------------------ 55

		

		Query: 61  TGPIGKPGTTDYNQLQNKPNLDAFAQKKETNSKITKLESSKADKSAVYSKAESKIELDKK 120

		                           NKP+L AFAQK+ETNSKITKLESSKADK+AVY KAESKIELDKK

		Sbjct: 56  ----------------NKPDLGAFAQKEETNSKITKLESSKADKNAVYLKAESKIELDKK 99

		

		Query: 121 LSLTGGIVTGQLQFKPNKSGIKPSSSVGGAINIDMSKSEGAAMVMYTNKDTTDGPLMILR 180

		           L+L GG++TGQLQFKPNKSGIKPSSSVGGAINIDMSKSEGA +V+Y+N DT+DGPLM LR

		Sbjct: 100 LNLKGGVMTGQLQFKPNKSGIKPSSSVGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLR 159

		

		Query: 181 SDKETFNQSALFVDYSGKTNAVNIVMRQPSTPNFSSALNITSANEGGSAMQIRGVEKALG 240

		           + KETFNQSALFVDYSGKTNAVNI MRQP+TPNFSSALNITS NE GSAMQIRGVEKALG

		Sbjct: 160 TGKETFNQSALFVDYSGKTNAVNIAMRQPTTPNFSSALNITSGNENGSAMQIRGVEKALG 219

		

		Query: 241 TLKITHENPNVKANYDENAAALSIDIVKKTN-GEGTAAQGIYINSSTGTTGKMLRIRNKN 299

		           TLKITHENPNV+ANYDENAAALSIDIVKK   G+GTAAQGIYINS++GTTGK+LRIRN  

		Sbjct: 220 TLKITHENPNVEANYDENAAALSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIRNLG 279

		

		Query: 300 EDKFYVGPDGGFHSGANSTVTGNLTVKDPTSEKHAATKKYVDEKIAELKKLIQK 353

		           +DKFYV  DGGF++   S + GNL +K+PT++ HAATK YVD ++ +LK L+  

		Sbjct: 280 DDKFYVKHDGGFYAKKTSQIDGNLKLKNPTADDHAATKAYVDSEVKKLKALLMD 333

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 35.6 bits (82), Expect = 6e-04

		 Identities = 34/195 (17%), Positives = 62/195 (31%), Gaps = 29/195 (14%)

		

		Query: 171 LKLDLNKANEQTASLQASINGLRQEYQDAERKLSASYQTGINGLKA-TMANDKY--DLKA 227

		           LKL    A   T   Q+S   L Q   +  R    S    +N L    + ++ Y  ++  

		Sbjct: 125 LKLTALGAEADTLKTQSS---LLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSE 181

		

		Query: 228 EIQATARGLSQE----YDNKLHQLSAKIKTTSSG------TTEAYENKLAGLRAEFTR-- 275

		           E       L +E    + N+ +Q    +    +           YEN     ++      

		Sbjct: 182 EEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFS 241

		

		Query: 276 --SNQG-----TRTELESQISGLRAVQQTTASQISQEIRDRTGAVSRVQQDLESYQR--- 325

		              ++         E E++        +   SQ+ Q   +   A    Q   + ++    

		Sbjct: 242 SLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEIL 301

		

		Query: 326 -RLQDAEDNYSSLTH 339

		            +L+   DN   LT 

		Sbjct: 302 DKLRQTTDNIGLLTL 316

		

		

		>FLGFLGJ#Flagellar protein FlgJ signature.

		          Length = 313

		

		 Score = 93.6 bits (232), Expect = 1e-23

		 Identities = 45/123 (36%), Positives = 64/123 (52%), Gaps = 8/123 (6%)

		

		Query: 23  SLTAAQAILESGWGKHA-------PHNALFGIKADSSWTGKSFDTKTQEEYQAGVVTDIV 75

		            L  AQA LESGWG+         P   LFG+KA  +W G   +  T E Y+ G    + 

		Sbjct: 172 HLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTE-YENGEAKKVK 230

		

		Query: 76  DRFRAYDSWTDSIIDHGKFLNDNPRYKAVVGETDYKKACHAIKDAGYATASGYAELLIQI 135

		            +FR Y S+ +++ D+   L  NPRY AV      ++   A++DAGYAT   YA  L  +

		Sbjct: 231 AKFRVYSSYLEALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNM 290

		

		Query: 136 IKE 138

		           I++

		Sbjct: 291 IQQ 293

		

		

		>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family

		           signature.

		          Length = 639

		

		 Score =  115 bits (290), Expect = 4e-29

		 Identities = 51/156 (32%), Positives = 81/156 (51%), Gaps = 8/156 (5%)

		

		Query: 12  KIRNFSIIAHIDHGKSTLADRILEK---TETVSSREMQAQLLDSMDLERERGITIKLNAI 68

		           KI N  ++AH+D GK+TL + +L        + S +      D+  LER+RGITI+    

		Sbjct: 2   KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61

		

		Query: 69  ELNYTARDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLA 128

		              +     E    ++IDTPGH+DF  EV RSL+  +GAIL++ A  G++AQT    +  

		Sbjct: 62  SFQW-----ENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHAL 116

		

		Query: 129 LDNDLEILPVINKIDLPAADPERVCHEVEDVIGLDA 164

		               +  +  INKID    D   V  ++++ +  + 

		Sbjct: 117 RKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEI 152

		

		

		

		 Score = 93.4 bits (232), Expect = 6e-22

		 Identities = 44/214 (20%), Positives = 93/214 (43%), Gaps = 16/214 (7%)

		

		Query: 171 SAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQVRIVNGIVKPGD 230

		           SAK  IGI+ ++E I  K  + T    + L   +F   Y   R  +  +R+ +G++   D

		Sbjct: 220 SAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRD 279

		

		Query: 231 KIQMMSNGKTFDVTEVGIFTP-KAVGRDFLATGDVGYVAASIKTVADTRVGDTVTLANNP 289

		            +++    K   +TE+      +    D   +G++  +      +    +GDT  L    

		Sbjct: 280 SVRISEKEKI-KITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSV-LGDTKLLPQRE 337

		

		Query: 290 AKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQFE--PETSQALGFGF 347

		             E         P++   + P +  +   L +AL ++  +D  L++     T + +    

		Sbjct: 338 RIENPL------PLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEII---- 387

		

		Query: 348 RCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVY 381

		              FLG + M+V    L+ ++++++ +  P+V+Y

		Sbjct: 388 -LSFLGKVQMEVTCALLQEKYHVEIEIKEPTVIY 420

		

		

		

		 Score = 43.3 bits (102), Expect = 2e-06

		 Identities = 21/104 (20%), Positives = 41/104 (39%), Gaps = 12/104 (11%)

		

		Query: 393 VSNPSEFPDPTRVAFIE----------EPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMD 442

		           VS P++F     +   +          EPY+  +I  PQE++      + +   + V   

		Sbjct: 510 VSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQ 569

		

		Query: 443 YIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYR 486

		            + +N V +  +IP   I  ++   L   T G +    ++  Y 

		Sbjct: 570 -LKNNEVILSGEIPARCI-QEYRSDLTFFTNGRSVCLTELKGYH 611

		

		

		>GPOSANCHOR#Gram-positive coccus surface protein anchor signature.

		          Length = 539

		

		 Score = 70.1 bits (171), Expect = 3e-15

		 Identities = 36/105 (34%), Positives = 48/105 (45%), Gaps = 12/105 (11%)

		

		Query: 250 QPGKPAPKTPEVPQKPDTAPHTPKTPQIPGQSKDVTPAPQNPSNRGLNKPQTQGGNQLAK 309

		           +  K A +  ++     +   TP             P  +    +G         NQ   

		Sbjct: 447 KLAKQAEELAKLRAGKASDSQTPDAK----------PGNKAVPGKGQAPQAGTKPNQ--N 494

		

		Query: 310 TPAAHDTHRQLPATGETTNPFFTAAAVAIMTTAGVVAVAKRQENN 354

		                +T RQLP+TGET NPFFTAAA+ +M TAGV AV KR+E N

		Sbjct: 495 KAPMKETKRQLPSTGETANPFFTAAALTVMATAGVAAVVKRKEEN 539

		

		

		>MYCMG045#Hypothetical mycoplasma lipoprotein (MG045) signature.

		          Length = 483

		

		 Score = 36.6 bits (84), Expect = 1e-04

		 Identities = 24/82 (29%), Positives = 42/82 (51%), Gaps = 4/82 (4%)

		

		Query: 31  SGSQSDKLVIYNWGDYIDPALLKKFTKETGIEVQYETFDSNEAMYTKIKQGGTTYDIAVP 90

		           S   S   V+ N+  YI P LL++   +    + + T+ SNE +         TY +AV 

		Sbjct: 21  SSCGSTTFVLANFESYISPLLLER--VQEKHPLTFLTYPSNEKLINGF--ANNTYSVAVA 76

		

		Query: 91  SDYTIDKMIKENLLNKLDKSKL 112

		           S Y + ++I+ +LL+ +D S+ 

		Sbjct: 77  STYAVSELIERDLLSPIDWSQF 98

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 66.0 bits (161), Expect = 8e-15

		 Identities = 23/131 (17%), Positives = 50/131 (38%), Gaps = 2/131 (1%)

		

		Query: 3   VLIIEDDPMVDFIHRNYLEKLNLFDRIISSDSMKAVQSILTDYVIDLILLDIHITDGNGI 62

		           +L+ +DD  +  +    L +      +  + +   +   +     DL++ D+ + D N  

		Sbjct: 6   ILVADDDAAIRTVLNQALSRAGY--DVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63

		

		Query: 63  QFLEKWRAQHIPCEVIIISAANDGNIIRDGFHLGIIDYLIKPFTFERFQESIQQFVTHRE 122

		             L + +       V+++SA N           G  DYL KPF        I + +   +

		Sbjct: 64  DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123

		

		Query: 123 HLANQQLEQAQ 133

		              ++  + +Q

		Sbjct: 124 RRPSKLEDDSQ 134

		

		

		>LIPPROTEIN48#Mycoplasma P48 major surface lipoprotein signature.

		          Length = 428

		

		 Score = 66.2 bits (161), Expect = 3e-14

		 Identities = 76/299 (25%), Positives = 120/299 (40%), Gaps = 45/299 (15%)

		

		Query: 36  DLKVAMVTDTGGVDDKSFNQSAWEGLQSWGKEMGLQKGTGFDYFQSTSESEYATNLDTAV 95

		            LK  ++TD G +DDKSFNQSA+E L++      + K TG +       S + +  ++A+

		Sbjct: 61  KLKPVLITDEGKIDDKSFNQSAFEALKA------INKQTGIEINNVEPSSNFESAYNSAL 114

		

		Query: 96  SGGYQLIYGIGFALKDAIAKAAGD------NEGVKFVIIDDIIEGKDNV-ASVTFADHEA 148

		           S G+++    GF  + +I +             +K + ID  IE +     S+ F   E+

		Sbjct: 115 SAGHKIWVLNGFKHQQSIKQYIDAHREELERNQIKIIGIDFDIETEYKWFYSLQFNIKES 174

		

		Query: 149 AYLAGIAAAKITKTK-----TVGFVGGMEGTVITRFEKGFEAGVKS---------VDDTI 194

		           A+  G A A     +      V   GG     +T F +GF  G+           +  T 

		Sbjct: 175 AFTTGYAIASWLSEQDESKRVVASFGGGAFPGVTTFNEGFAKGILYYNQKHKSSKIYHTS 234

		

		Query: 195 QVKVDYAGSFGDAAKGKTIAAAQYAAGADVIYQAAGG---TGAGVFNEAKAINEKRSEAD 251

		            VK+D +G          I     +  ADV Y         G   F   +  N+ +    

		Sbjct: 235 PVKLD-SGFTAGEKMNTVINNVLSSTPADVKYNPHVILSVAGPATFETVRLANKGQ---- 289

		

		Query: 252 KVWVIGVDRDQKDEGKYTSKDGKEANFVLASSIKEVGKAVQLINKQVADKKFPGGKTTV 310

		             +VIGVD DQ        +D      +L S +K + +AV      +  +K  G K  V

		Sbjct: 290 --YVIGVDSDQG-----MIQDKDR---ILTSVLKHIKQAVYETLLDLILEKEEGYKPYV 338

		

		

		>PF06580#Sensor histidine kinase

		          Length = 349

		

		 Score = 39.1 bits (91), Expect = 2e-05

		 Identities = 15/75 (20%), Positives = 31/75 (41%), Gaps = 5/75 (6%)

		

		Query: 312 YGKIFYFQNQVNRSLRMDKALLKQLITILFDNAIKY----TDKNGIIEIIVKTTDKNLLI 367

		           +     F+NQ+N ++  D  +   L+  L +N IK+      + G I +     +  + +

		Sbjct: 236 FEDRLQFENQINPAIM-DVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTL 294

		

		Query: 368 SVIDNGPGITDEEKK 382

		            V + G       K+

		Sbjct: 295 EVENTGSLALKNTKE 309

		

		

		>PF05272#Virulence-associated E family protein

		          Length = 892

		

		 Score = 33.5 bits (76), Expect = 7e-04

		 Identities = 18/41 (43%), Positives = 23/41 (56%), Gaps = 2/41 (4%)

		

		Query: 36  KGELVVIL-GASGAGKSTVLNILGGMD-TVDAGQVIIDGKD 74

		           K +  V+L G  G GKST++N L G+D   D    I  GKD

		Sbjct: 594 KFDYSVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKD 634

		

		

		>HTHTETR#TetR bacterial regulatory protein HTH signature.

		          Length = 215

		

		 Score = 41.2 bits (96), Expect = 6e-07

		 Identities = 13/48 (27%), Positives = 25/48 (52%)

		

		Query: 4  RHTETKAYVKTALTTLLTEQSFETLTVSDLTKKAGINRGTFYLHYTDK 51

		             ET+ ++      L ++Q   + ++ ++ K AG+ RG  Y H+ DK

		Sbjct: 8  EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDK 55

		

		

		>PF06580#Sensor histidine kinase

		          Length = 349

		

		 Score = 28.3 bits (63), Expect = 0.024

		 Identities = 19/109 (17%), Positives = 32/109 (29%), Gaps = 15/109 (13%)

		

		Query: 19  LVGLVLLSVFGWVVGITGGYIYLPYSYRWLSWGMDNFPNLLDSALSYYYFWTALVLFVIT 78

		           ++  + +S+ G V  +T  Y        WL   M                  A V+    

		Sbjct: 42  MIFNIAISLMGLV--LTHAYRSFIKRQGWLKLNMGQI---------ILRVLPACVVIG-- 88

		

		Query: 79  FLALLVIILYPRIYTEVQLRHKNKKGTLLLKKSAIESYVATAIQTAGLM 127

		            +  +      R+   +    K    TL L  S I + V      + L 

		Sbjct: 89  MVWFVANTSIWRLLAFIN--TKPVAFTLPLALSIIFNVVVVTFMWSLLY 135

		

		

		>BACTRLTOXIN#Bacterial toxin signature.

		          Length = 266

		

		 Score =  353 bits (907), Expect = e-126

		 Identities = 149/261 (57%), Positives = 193/261 (73%), Gaps = 6/261 (2%)

		

		Query: 6   RILVVACVVFCAQLLSIS---VFASSQPDPTPEQLNKSSQFTGVMGNLRCLYDNHFVEGT 62

		           R+ +   ++  A +L IS   V A SQPDP P+ L+KSS+FTG MGN++ LYD+H+V  T

		Sbjct: 4   RLFISRVILIFALILVISTPNVLAESQPDPMPDDLHKSSEFTGTMGNMKYLYDDHYVSAT 63

		

		Query: 63  NVRSTGQLLQHDLIFPIKDLKLKNYDSVKTEFNSKDLAAKYKNKDVDIFGSNYYYNCYYS 122

		            V+S  + L HDLI+ I D KLKNYD VKTE  ++DLA KYK++ VD++GSNYY NCY+S

		Sbjct: 64  KVKSVDKFLAHDLIYNISDKKLKNYDKVKTELLNEDLAKKYKDEVVDVYGSNYYVNCYFS 123

		

		Query: 123 EGNSCKNA--KKTCMYGGVTEHHRNQI-EGKFPNITVKVYEDNENILSFDITTNKKQVTV 179

		             ++       KTCMYGG+T+H  N    G   N+ V+VYE+  N +SF++ T+KK VT 

		Sbjct: 124 SKDNVGKVTGGKTCMYGGITKHEGNHFDNGNLQNVLVRVYENKRNTISFEVQTDKKSVTA 183

		

		Query: 180 QELDCKTRKILVSRKNLYEFNNSPYETGYIKFIESSGDSFWYDMMPAPGAIFDQSKYLML 239

		           QELD K R  L+++KNLYEFN+SPYETGYIKFIE++G++FWYDMMPAPG  FDQSKYLM+

		Sbjct: 184 QELDIKARNFLINKKNLYEFNSSPYETGYIKFIENNGNTFWYDMMPAPGDKFDQSKYLMM 243

		

		Query: 240 YNDNKTVSSSAIAIEVHLTKK 260

		           YNDNKTV S ++ IEVHLT K

		Sbjct: 244 YNDNKTVDSKSVKIEVHLTTK 264

		

		

		>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature.

		          Length = 1541

		

		 Score = 32.0 bits (72), Expect = 0.002

		 Identities = 13/42 (30%), Positives = 22/42 (52%)

		

		Query: 64   TKYAVAESVQKVEELSLAQKEIEQNAEQAKVTAEAAEKQAKS 105

		            T+    +    VE+   A+ E E+  E  KVT++ + KQ +S

		Sbjct: 1095 TQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQS 1136

		

		

		>PF07212#Hyaluronoglucosaminidase

		          Length = 336

		

		 Score =  385 bits (990), Expect = e-138

		 Identities = 168/235 (71%), Positives = 197/235 (83%), Gaps = 2/235 (0%)

		

		Query: 1   MSLAGGIVTGQLRLKPN-SGIEKSSSTGGAINIDMSKSKGAAMVMYTNKDTTDGPLMILR 59

		           ++L GG++TGQL+ KPN SGI+ SSS GGAINIDMSKS+GA +V+Y+N DT+DGPLM LR

		Sbjct: 100 LNLKGGVMTGQLQFKPNKSGIKPSSSVGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLR 159

		

		Query: 60  SNKDTFDQSVQFVDYRGKTNAVNIVMRQPPTPNFSSALNITSANEGGSAMQIRGVEKALG 119

		           + K+TF+QS  FVDY GKTNAVNI MRQP TPNFSSALNITS NE GSAMQIRGVEKALG

		Sbjct: 160 TGKETFNQSALFVDYSGKTNAVNIAMRQPTTPNFSSALNITSGNENGSAMQIRGVEKALG 219

		

		Query: 120 TLKITHENPSVDKEYDKNAAALSIDIVKKKKGGGDGTAAQGIFINSSSGTTGKLLRIRNK 179

		           TLKITHENP+V+  YD+NAAALSIDIVKK+K GG GTAAQGI+INS+SGTTGKLLRIRN 

		Sbjct: 220 TLKITHENPNVEANYDENAAALSIDIVKKQK-GGKGTAAQGIYINSTSGTTGKLLRIRNL 278

		

		Query: 180 NEDKFYVNPDGGFHSYADSIVDGNLTVKNPTSGKHAATKDYVDKKFDELKKLIQK 234

		            +DKFYV  DGGF++   S +DGNL +KNPT+  HAATK YVD +  +LK L+  

		Sbjct: 279 GDDKFYVKHDGGFYAKKTSQIDGNLKLKNPTADDHAATKAYVDSEVKKLKALLMD 333

		

		

		>PF06872#EspG protein

		          Length = 398

		

		 Score = 31.2 bits (70), Expect = 0.002

		 Identities = 15/35 (42%), Positives = 22/35 (62%), Gaps = 3/35 (8%)

		

		Query: 59  RGVGDVKMETEAIDIPFD---VLKKILGYKDGSSS 90

		           RG+G+ K+    +DIP D   +L+  LG KD +SS

		Sbjct: 208 RGLGNSKLSLNGVDIPADAQKLLRNTLGLKDTNSS 242

		

		

		>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature.

		          Length = 1541

		

		 Score = 32.7 bits (74), Expect = 0.002

		 Identities = 30/150 (20%), Positives = 51/150 (34%), Gaps = 21/150 (14%)

		

		Query: 134  KAAVQRAVEQVTVNYDIYEALGSKRNELYAEIEKSLSERLAKESIELVSVTLTDQDAGDE 193

		             A V  A            A  S+  E  AE  K  S+ + K   +    T  +++   E

		Sbjct: 1017 IARVDEAPVP-----PPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKE 1071

		

		Query: 194  -----------IEKAIKDESVKQKQVDSAKQ-----DKEKAKIEAETKQIQAQAEADAQV 237

		                        E A      K+ Q    K+      +EKAK+E E  Q   +  +    

		Sbjct: 1072 AKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSP 1131

		

		Query: 238  IKAKGEAESNNTKAASITDNLIKMKEAEAR 267

		             + + E      + A   D  + +KE +++

		Sbjct: 1132 KQEQSETVQPQAEPARENDPTVNIKEPQSQ 1161

		

		

		>PF06580#Sensor histidine kinase

		          Length = 349

		

		 Score = 25.2 bits (55), Expect = 0.048

		 Identities = 7/45 (15%), Positives = 18/45 (40%)

		

		Query: 29  LFLAIAIFGIMVTVSYFSYRDAQQYYEPQITGLRTQLSRTQKQLK 73

		           +   + +   M ++ YF +   + Y + +I   +      + QL 

		Sbjct: 120 IIFNVVVVTFMWSLLYFGWHFFKNYKQAEIDQWKMASMAQEAQLM 164

		

		

		>HTHTETR#TetR bacterial regulatory protein HTH signature.

		          Length = 215

		

		 Score = 48.5 bits (115), Expect = 2e-09

		 Identities = 13/64 (20%), Positives = 30/64 (46%)

		

		Query: 5  RQIKKTKTAIYSAFIALLQKKEYSKITVRDMITLANVGRSTFYAHYESKEMLQKELCEEL 64

		          ++ ++T+  I    + L  ++  S  ++ ++   A V R   Y H++ K  L  E+ E  

		Sbjct: 7  QEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELS 66

		

		Query: 65 FHHL 68

		            ++

		Sbjct: 67 ESNI 70

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 44.4 bits (105), Expect = 5e-07

		 Identities = 21/112 (18%), Positives = 45/112 (40%), Gaps = 13/112 (11%)

		

		Query: 170 QQLQDLNDAYADAQAEVNKAQIALNDTVVISSVSGTVVE-----VNNDIDPSSKNSQTLV 224

		            +L+   D       E+ K +     +V+ + VS  V +         +      ++TL+

		Sbjct: 302 DKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTT----AETLM 357

		

		Query: 225 HVATEGQ-LQVKGTLTEYDLANVKVGQSVKIKSKVYSNQEW---TGKISYVS 272

		            +  E   L+V   +   D+  + VGQ+  IK + +    +    GK+  ++

		Sbjct: 358 VIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNIN 409

		

		

		

		 Score = 37.5 bits (87), Expect = 9e-05

		 Identities = 24/185 (12%), Positives = 53/185 (28%), Gaps = 29/185 (15%)

		

		Query: 21  ITLVLIITGVVLWKQQQNTLTADIAKEPYSTVSVTEGSIASSTLFSGTVKALSEEYIYFD 80

		             ++  +    +         + +       V+   G +  S   S  +K +    +   

		Sbjct: 62  YFIMGFLVIAFIL--------SVLG--QVEIVATANGKLTHSG-RSKEIKPIENSIV--- 107

		

		Query: 81  ANKGNDATVTVKVGDQVTQGQQLVQYNTTTA-------QSAYDTAVRSLNKIGRQINHLK 133

		                   + VK G+ V +G  L++     A       QS+   A     +       ++

		Sbjct: 108 ------KEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIE 161

		

		Query: 134 TYGVPAV--STETNKDEATGEETTTTVQPSAQQNANYKQQLQDLNDAYADAQAEVNKAQI 191

		              +P +    E      + EE         +Q + ++ Q           +AE      

		Sbjct: 162 LNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLA 221

		

		Query: 192 ALNDT 196

		            +N  

		Sbjct: 222 RINRY 226

		

		

		>LIPPROTEIN48#Mycoplasma P48 major surface lipoprotein signature.

		          Length = 428

		

		 Score = 30.4 bits (68), Expect = 0.012

		 Identities = 28/122 (22%), Positives = 50/122 (40%), Gaps = 11/122 (9%)

		

		Query: 15  KKTSYVTFFLMPILTTLLALSLSFSNNNQAKIGILDKDNSQISKQFIAQLKQNKKYDIFT 74

		           KK+  +   L PI   L A+++S  NN+++ I   +KD S+ +       +  K  ++  

		Sbjct: 2   KKSKKILLGLSPIAAILPAVAVSCGNNDESNISFKEKDISKYTTTNANGKQVVKNAELLK 61

		

		Query: 75  KIKKEHI--DHYLQDKSL-----EAVLTIDKGFS-DKVLQGKSQKL--NIRSIANSEITE 124

		            +K   I  +  + DKS      EA+  I+K    +      S        S  ++    

		Sbjct: 62  -LKPVLITDEGKIDDKSFNQSAFEALKAINKQTGIEINNVEPSSNFESAYNSALSAGHKI 120

		

		Query: 125 WV 126

		           WV

		Sbjct: 121 WV 122

		

		

		>TYPE3IMSPROT#Type III secretion system inner membrane S protein

		           family signature.

		          Length = 354

		

		 Score = 30.9 bits (70), Expect = 0.004

		 Identities = 15/76 (19%), Positives = 32/76 (42%), Gaps = 1/76 (1%)

		

		Query: 37  SYQDFLDVLLSLFQFVVIILVLFFYSATINLGEVLTFLTQTSWHWQILCYLVLYLMAIIE 96

		           S +  ++ L S+ + V++ ++++      NL  +L   T        L   +L  + +I 

		Sbjct: 133 SIKSLVEFLKSILKVVLLSILIWII-IKGNLVTLLQLPTCGIECITPLLGQILRQLMVIC 191

		

		Query: 97  MTLLVLILIFDVLLQK 112

		               V+I I D   + 

		Sbjct: 192 TVGFVVISIADYAFEY 207

		

		

		>GPOSANCHOR#Gram-positive coccus surface protein anchor signature.

		          Length = 539

		

		 Score = 32.3 bits (73), Expect = 0.004

		 Identities = 41/225 (18%), Positives = 86/225 (38%), Gaps = 22/225 (9%)

		

		Query: 171 NLYDNIARYKERLKDKSDQLTTFRNARKYAFISNLVGGKKQFEANVSEIKRLEYDLAHLQ 230

		               ++ +  E   + S   +  +     A  + L   + + E  +          +   

		Sbjct: 225 ARKADLEKALEGAMNFSTADSA-KIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKI 283

		

		Query: 231 DTHQDKIDSDDIEKNQQKLQLRNTKLELESSLRD------KQRRLKLLDISIEFGLYPTE 284

		            T + +  + + EK   + Q +      +S  RD       +++L+     +E     +E

		Sbjct: 284 KTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISE 343

		

		Query: 285 SDLTELQQYFPDTNLKKLYEVEAYHKKLETIL------------DSEFSTE-RESLIAEI 331

		           +    L++   D + +   ++EA H+KLE               D + S E ++ +   +

		Sbjct: 344 ASRQSLRRDL-DASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKAL 402

		

		Query: 332 DDLESQLTTLNQELQELGNIPNLS-SEYLENYSKLTATINALKEQ 375

		           ++  S+L  L +  +EL     L+  E  E  +KL A   ALKE+

		Sbjct: 403 EEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEK 447

		

		

		>PF05043#Transcriptional activator

		          Length = 493

		

		 Score = 25.7 bits (56), Expect = 0.033

		 Identities = 10/82 (12%), Positives = 28/82 (34%), Gaps = 10/82 (12%)

		

		Query: 10  YLTNLPALAHDSLLLSN----VSYQAT-----EALLKLYDQSRSLNKQVFLAFDKASSYS 60

		            L+++ +   D +  S+                     +  S   +   F+ F++     

		Sbjct: 45  DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQAE 104

		

		Query: 61  PDANQL-LSENTVLRLSSNGNE 81

		               +  +S +++ R+ S  N+

		Sbjct: 105 SICKEFYISSSSLYRIISQINK 126

		

		

		>TCRTETA#Tetracycline resistance protein signature.

		          Length = 399

		

		 Score = 37.9 bits (88), Expect = 6e-05

		 Identities = 28/141 (19%), Positives = 59/141 (41%), Gaps = 13/141 (9%)

		

		Query: 52  SVIGVLFNLFGGVIADSFKR----KKIIITTNILCGTACLVLSFLTKEQWLVYAIVLTNV 107

		           +  G+L +L   +I          ++ ++   I  GT  ++L+F T   W+ + I+   V

		Sbjct: 253 AAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFAT-RGWMAFPIM---V 308

		

		Query: 108 ILAFMSAFSSPSYKAFTKEIVKKDGISQLNSLLETTSTVIKVTVPMVAIFLYKLLGIHGV 167

		           +LA       P+ +A     V ++   QL   L   +++  +  P++   +Y       +

		Sbjct: 309 LLAS-GGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYA----ASI 363

		

		Query: 168 LLLDGLSFLIAALLISFILPV 188

		              +G +++  A L    LP 

		Sbjct: 364 TTWNGWAWIAGAALYLLCLPA 384

		

		

		>GPOSANCHOR#Gram-positive coccus surface protein anchor signature.

		          Length = 539

		

		 Score = 47.8 bits (113), Expect = 2e-07

		 Identities = 47/313 (15%), Positives = 94/313 (30%), Gaps = 10/313 (3%)

		

		Query: 209 AKVAKQFLELDANRKQLQLDILVKDIDIAQERQTKDTEALAVLQQDLASYYAKRQSMEED 268

		           + VA +       + Q + D    + +  + + +  +     L+        +  + +E 

		Sbjct: 41  SAVATRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEK 100

		

		Query: 269 YQKFKQKKQVLSQESDQTQTTLLELTKLIADLEKQIELVKLESGQ---EAEKKAEAKKHL 325

		            +K  +     + +  + +    +L K +            +      E    A  K  L

		Sbjct: 101 LRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADL 160

		

		Query: 326 EQLQEQLDGFQAEEKQRTEQLLHIDQQLCDVKQQLNELSNALERFSSDPDQLMETLREEF 385

		           E+  E    F   +  + + L      L   + +L +       FS+     ++TL  E 

		Sbjct: 161 EKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEK 220

		

		Query: 386 VLLMQKEAALSNQLTALKAHLDKEKQARQHKAQEYQLLVTKLDQLNDESQKAQAHYKAQK 445

		             L  ++A L   L         +    +    E   L  +  +L    + A     A  

		Sbjct: 221 AALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADS 280

		

		Query: 446 EQVEMLLQNYQEGDKRVQELERDYQLNQERLFDLLDQ-------KKGKEARKASLESIQK 498

		            +++ L       +    +LE   Q+       L          KK  EA    LE   K

		Sbjct: 281 AKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNK 340

		

		Query: 499 SHSQFYAGVRAVL 511

		                   +R  L

		Sbjct: 341 ISEASRQSLRRDL 353

		

		

		

		 Score = 30.4 bits (68), Expect = 0.049

		 Identities = 39/243 (16%), Positives = 89/243 (36%), Gaps = 18/243 (7%)

		

		Query: 169 KYKTRKKETQIKLNQTQDNLDRLEDIIYELDTQLAPLEKQAKVAKQFLELDANRKQLQLD 228

		             +   +            +  LE     L+ + A LEK  + A  F          ++ 

		Sbjct: 229 DLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTA----DSAKIK 284

		

		Query: 229 ILVKDIDIAQERQTKDTEALAVLQ-------QDLASYYAKRQSMEEDYQKFKQKKQVLSQ 281

		            L  +    +  +        VL        +DL +    ++ +E ++QK +++ ++   

		Sbjct: 285 TLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEA 344

		

		Query: 282 ESDQTQTTLLELTKLIADLEKQIELVKLESGQEAEKKAEAKKHLEQLQEQLDGFQAEEKQ 341

		                +  L    +    LE + + ++       E+   ++   + L+  LD  +  +KQ

		Sbjct: 345 SRQSLRRDLDASREAKKQLEAEHQKLE-------EQNKISEASRQSLRRDLDASREAKKQ 397

		

		Query: 342 RTEQLLHIDQQLCDVKQQLNELSNALERFSSDPDQLMETLREEFVLLMQKEAALSNQLTA 401

		             + L   + +L  +++   EL  + +    +  +L   L  E   L +K A  + +L  

		Sbjct: 398 VEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEKLAKQAEELAK 457

		

		Query: 402 LKA 404

		           L+A

		Sbjct: 458 LRA 460

		

		

		>PF06580#Sensor histidine kinase

		          Length = 349

		

		 Score = 40.6 bits (95), Expect = 8e-06

		 Identities = 29/188 (15%), Positives = 70/188 (37%), Gaps = 35/188 (18%)

		

		Query: 253 DETNRMMRMISDLL--NLSRIDNQVTQLAVEMTNFTAFITSILNRFDLVKNQHTGTGKVY 310

		            +   M+  +S+L+  +L   + +   LA E+T   +++     +F   +++     ++ 

		Sbjct: 191 TKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQF---EDRLQFENQIN 247

		

		Query: 311 EIVRDYPITSVWIEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQG 370

		             + D  +  + ++        ++EN + + I   P GGKI ++    +  + + + + G

		Sbjct: 248 PAIMDVQVPPMLVQT-------LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTG 300

		

		Query: 371 LGIPKTDLPLIFDRFYRVDKARSRAQGGTGLGLAIAKEIIKQ---QHHGFIWAKSDYGKG 427

		               K                    +  TG GL   +E ++         I      GK 

		Sbjct: 301 SLALKNT------------------KESTGTGLQNVRERLQMLYGTEAQ-IKLSEKQGKV 341

		

		Query: 428 STFTIVLP 435

		               +++P

		Sbjct: 342 -NAMVLIP 348

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 91.8 bits (228), Expect = 1e-23

		 Identities = 29/133 (21%), Positives = 65/133 (48%), Gaps = 1/133 (0%)

		

		Query: 3   KILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEEKPDLIILDLMLPELDGLE 62

		            IL+ DD+  I  ++   L++ GYD+    +             DL++ D+++P+ +  +

		Sbjct: 5   TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64

		

		Query: 63  VAKEIRKT-SHVPIIMLSAKDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTET 121

		           +   I+K    +P++++SA+++    +   E GA DY+ KPF   EL+  +   L   + 

		Sbjct: 65  LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124

		

		Query: 122 IETAVAEENASSG 134

		             + + +++    

		Sbjct: 125 RPSKLEDDSQDGM 137

		

		

		>TCRTETB#Tetracycline resistance protein TetB signature.

		          Length = 458

		

		 Score = 41.4 bits (97), Expect = 6e-06

		 Identities = 27/101 (26%), Positives = 40/101 (39%), Gaps = 4/101 (3%)

		

		Query: 66  LTVSYGLAKFYMGALGDRVSLRKLFSISLGASALICILIGFFNSSMVVLGILLVLCGVVQ 125

		           LT S G A    G L D++ +++L    +  +    + IGF   S   L I+        

		Sbjct: 60  LTFSIGTA--VYGKLSDQLGIKRLLLFGIIINCFGSV-IGFVGHSFFSLLIMARFIQGAG 116

		

		Query: 126 GALAPA-SQAMIANYFPNKTRGGAIAGWNISQNMGSALLPL 165

		            A  PA    ++A Y P + RG A         MG  + P 

		Sbjct: 117 AAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPA 157

		

		

		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

		           signature.

		          Length = 261

		

		 Score = 99.0 bits (246), Expect = 3e-27

		 Identities = 67/252 (26%), Positives = 109/252 (43%), Gaps = 24/252 (9%)

		

		Query: 3   KVVLVTGCASGIGYAQARYFLRQGHHVYGVDKSDKPDLNGNFHFIKLDLSSELSPL---- 58

		           K+  +TG A GIG A AR    QG H+  VD + +               +E  P     

		Sbjct: 9   KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68

		

		Query: 59  -----------FKVVPSVDILCNTAGILDAYKPLLDVSDEEVEHLFDINFFATVKLTRHY 107

		                       + +  +DIL N AG+L     +  +SDEE E  F +N       +R  

		Sbjct: 69  SAAIDEITARIEREMGPIDILVNVAGVLRP-GLIHSLSDEEWEATFSVNSTGVFNASRSV 127

		

		Query: 108 LRRMVEKQSGVIINMCSIASFIAGGGGVAYTSSKHALAGFTRQLALDYAKDQIHIFGIAP 167

		            + M++++SG I+ + S  + +      AY SSK A   FT+ L L+ A+  I    ++P

		Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187

		

		Query: 168 GAVKTAM-----TASDFEP---GGLADWVARETPIGRWTEPDEVAELTGFLASGKARSMQ 219

		           G+ +T M        +       G  +      P+ +  +P ++A+   FL SG+A  + 

		Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHIT 247

		

		Query: 220 GEIVKIDGGWTL 231

		              + +DGG TL

		Sbjct: 248 MHNLCVDGGATL 259

		

		

		>INTIMIN#Intimin signature.

		          Length = 939

		

		 Score = 27.3 bits (60), Expect = 0.042

		 Identities = 16/60 (26%), Positives = 23/60 (38%), Gaps = 6/60 (10%)

		

		Query: 65  NGVKQSYPGEKEIKIINPSTQEVTRCYRISGWRADSQGSYTVTLDSPLQETDVVSLQIAD 124

		           NGV Q+         I   T  ++     +    +  G  TVTL S      VVS + A+

		Sbjct: 587 NGVAQA--NVPVSFNIVSGTAVLSA----NSANTNGSGKATVTLKSDKPGQVVVSAKTAE 640

		

		

		>BINARYTOXINA#Clostridial binary toxin A signature.

		          Length = 454

		

		 Score = 38.5 bits (89), Expect = 1e-05

		 Identities = 42/170 (24%), Positives = 70/170 (41%), Gaps = 27/170 (15%)

		

		Query: 81  INTSLDKAKGKLSQLTPELRDQVAQLDAATHRLVIPWNIVVYRYVYETFLRDIGVSHADL 140

		           IN  L  + G L+   PEL  +V  ++ A     IP N++VYR          G     L

		Sbjct: 295 INNYL-ISNGPLNNPNPELDSKVNNIENALKLTPIPSNLIVYRRS--------GPQEFGL 345

		

		Query: 141 TSYYRNHQFDPHILCKIK---------LGTRYTKHSFMSTT--ALKNGAMTHRPVEVRIC 189

		           T     + F+     KI+          G   T  +F+ST+  ++   A   R + +RI 

		Sbjct: 346 TLTSPEYDFN-----KIENIDAFKEKWEGKVITYPNFISTSIGSVNMSAFAKRKIILRIN 400

		

		Query: 190 VKKGAKAAFVEPYSAVPSEVELLFPRGCQLEV--VGAYVSQDHKKLHIEA 237

		           + K +  A++        E E+L   G + ++  V +Y      KL ++A

		Sbjct: 401 IPKDSPGAYLSAIPGYAGEYEVLLNHGSKFKINKVDSYKDGTVTKLILDA 450

		

		

		>SUBTILISIN#Subtilisin serine protease family (S8) signature.

		          Length = 326

		

		 Score = 92.2 bits (229), Expect = 5e-22

		 Identities = 42/160 (26%), Positives = 64/160 (40%), Gaps = 24/160 (15%)

		

		Query: 240 DIDWTQTDDDTKYESHGMHVTGIVAGNSKEAAATGERFLGIAPEAQVMFMRVFANDVMGS 299

		           + D     D      HG HV G +A             +G+APEA ++ ++V      G 

		Sbjct: 74  EGDPEIFKDY---NGHGTHVAGTIAAT-----ENENGVVGVAPEADLLIIKVLNKQGSGQ 125

		

		Query: 300 AESLFIKAIEDAVALGADVINLSLGTANGAQLSGSKPLMEAIEKAKKAGVSVVVAAGNER 359

		            + + I+ I  A+    D+I++SLG            L EA++KA  + + V+ AAGNE 

		Sbjct: 126 YDWI-IQGIYYAIEQKVDIISMSLGGP-----EDVPELHEAVKKAVASQILVMCAAGNEG 179

		

		Query: 360 VYGSDHDDPLATNPDYGLVGSPSTGRTPTSVAAINSKWVI 399

		                 D+          +G P       SV AIN     

		Sbjct: 180 DGDDRTDE----------LGYPGCYNEVISVGAINFDRHA 209

		

		

		

		 Score = 78.7 bits (194), Expect = 2e-17

		 Identities = 36/147 (24%), Positives = 58/147 (39%), Gaps = 18/147 (12%)

		

		Query: 537 FDSVVSKAPSQKGNEMNHFSNWGLTSDGYLKPDITAPGGDIYSTYNDNHYGSQTGTSMAS 596

		           ++ V+S          + FSN         + D+ APG DI ST     Y + +GTSMA+

		Sbjct: 194 YNEVISVGAINFDRHASEFSNSNN------EVDLVAPGEDILSTVPGGKYATFSGTSMAT 247

		

		Query: 597 PQIAGASLLVKQ-YLEKTQPNLPKEKIADIVKNLLMSNAQIHVNPETKTTTSPRQQGAGL 655

		           P +AGA  L+KQ      + +L        +   L+               SP+ +G GL

		Sbjct: 248 PHVAGALALIKQLANASFERDL----TEPELYAQLIKRT-------IPLGNSPKMEGNGL 296

		

		Query: 656 LNIDGAVTSGLYVTGKDNYGSISLGNI 682

		           L +            +   G +S  ++

		Sbjct: 297 LYLTAVEELSRIFDTQRVAGILSTASL 323

		

		

		

		 Score = 40.6 bits (95), Expect = 4e-05

		 Identities = 11/34 (32%), Positives = 18/34 (52%), Gaps = 1/34 (2%)

		

		Query: 103 HDWVKTKGAWDKGYKGQGKVVAVIDTGIDPAHQS 136

		            + ++    W++   G+G  VAV+DTG D  H  

		Sbjct: 26  VEMIQAPAVWNQTR-GRGVKVAVLDTGCDADHPD 58

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 46.0 bits (109), Expect = 3e-08

		 Identities = 21/118 (17%), Positives = 51/118 (43%), Gaps = 6/118 (5%)

		

		Query: 2   KILLIDDHRLFAKSIQLLFQQYD-EVDVIDTITSHFNDVTIDLSKYDIILLDINLTNISK 60

		            IL+ DD       +     +   +V +     + +  +       D+++ D+ +     

		Sbjct: 5   TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWI--AAGDGDLVVTDVVM---PD 59

		

		Query: 61  ENGLEIAKELIQSTPHLKVVMLTGYVKSIYRERAKKVGAYGFVDKNIDPKQLISILKK 118

		           EN  ++   + ++ P L V++++     +   +A + GAY ++ K  D  +LI I+ +

		Sbjct: 60  ENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117

		

		

		>ARGREPRESSOR#Bacterial arginine repressor signature.

		          Length = 149

		

		 Score = 29.8 bits (67), Expect = 0.006

		 Identities = 21/85 (24%), Positives = 38/85 (44%), Gaps = 11/85 (12%)

		

		Query: 1  MKKKERHEKILDILKVDGFIKVKDIIDEM-----NISDMTARRDLDTLADKGLL-IRTHG 54

		          M K +RH KI +I+  +      +++D +     N++  T  RD+  L    L+ + T+ 

		Sbjct: 1  MNKGQRHIKIREIITANEIETQDELVDILKKDGYNVTQATVSRDIKEL---HLVKVPTNN 57

		

		Query: 55 GAQYLDYSSAKDEGHEKTHTEKKVL 79

		          G+    YS   D+        K+ L

		Sbjct: 58 GSYK--YSLPADQRFNPLSKLKRSL 80