>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 50.3 bits (120), Expect = 2e-10 Identities = 21/64 (32%), Positives = 39/64 (60%) Query: 5 QKGFTLIELMIVIAIVGILAAVALPAYQDYTARAQVSEAILLAEGQKSAVTEYYLNHGEW 64 Q+GFTL+E+M+VI I+G+LA++ +P +A +A+ ++A+ Y L++ + Sbjct: 7 QRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDNHHY 66 Query: 65 PGNN 68 P N Sbjct: 67 PTTN 70
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 71.9 bits (176), Expect = 7e-19 Identities = 40/105 (38%), Positives = 57/105 (54%), Gaps = 2/105 (1%) Query: 3 GLIIEDLQEGFGKEAVKGKEITVHYTGWLENGTKFDSSLDRRQPLTITLGVGQVIKGWDE 62 GL + + G G + K +TV YTG L +GT FDS+ +P T V QVI GW E Sbjct: 127 GLQYKIIDAGTGAKPGKSDTVTVEYTGTLIDGTVFDSTEKAGKPATFQ--VSQVIPGWTE 184 Query: 63 GFGGMKEGGKRKLTIPSEMGYGAHGAGGVIPPHATLIFEVELLKV 107 M G ++ +P+++ YG GG I P+ TLIF++ L+ V Sbjct: 185 ALQLMPAGSTWEVFVPADLAYGPRSVGGPIGPNETLIFKIHLISV 229
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 173 bits (439), Expect = 3e-53 Identities = 84/355 (23%), Positives = 142/355 (40%), Gaps = 48/355 (13%) Query: 3 KILVTGGAGFIGSAVVRHIIRNTRDAVVNVDKLT--YAGNLESLT-EVADNPRYAFEQVD 59 K LVTG AGFIG V + ++ VV +D L Y +L+ E+ P + F ++D Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAG-HQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 60 ICDRAELDRVFAQYRPDAVMHLAAESHVDRSIGSAGEFIQTNIVGTFNLLEAARAYWQQM 119 + DR + +FA + V V S+ + + +N+ G N+LE R Q Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ- 119 Query: 120 PSEQHEAFRFHHISTDEVYGDLGGTDDLFTETAPYA-PSSPYSASKASSDHLVRAWLRTY 178 + S+ VYG F+ P S Y+A+K +++ + + Y Sbjct: 120 --------HLLYASSSSVYGL--NRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLY 169 Query: 179 GLPTIVTNCSNNYGPYHFPEKLIPLMILNALDGKPLPVYGDGMQIRDWLFVEDHARALYQ 238 GLP YGP+ P+ + L+GK + VY G RD+ +++D A A+ + Sbjct: 170 GLPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIR 229 Query: 239 VV------------------TEGVVGETYNIGGHNEKANIEVVKTICALLEELAPEKPAG 280 + YNIG + ++ ++ + E G Sbjct: 230 LQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQAL---------EDALG 280 Query: 281 VARYEDLITFVQDRPGHDVRY-AVDAAKIRRDLGWLPLETFESGLRKTVQWYLDN 334 + E + +PG DV + D + +G+ P T + G++ V WY D Sbjct: 281 I---EAKKNMLPLQPG-DVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDF 331
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 171 bits (435), Expect = 6e-53 Identities = 88/352 (25%), Positives = 149/352 (42%), Gaps = 51/352 (14%) Query: 3 KILVTGGTGFIGSHTVVSLLKSGHQVVILDNLCNSSINIL---PRLKTITGQEIPFYQGD 59 K LVTG GFIG H LL++GHQVV +DNL N ++ RL+ + F++ D Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNL-NDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 60 IRDREILRRIFAENRIDSVIHFAGLKAVGESVAEPMKYYDNNVSGSLVLAEEMARAGVFS 119 + DRE + +FA + V AV S+ P Y D+N++G L + E + Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 120 IVFSSSATVYGDPGKVPYTEDMPPGDTTSPYGASKSMVERI------LTDIQKADPRWSM 173 ++++SS++VYG K+P++ D S Y A+K E + L + Sbjct: 121 LLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGL-------PA 173 Query: 174 ILLRYFNPIGAHESGLIGEQPNGIPNNLLP-YICQVAAGKLPQLAVFGDDYPTPDGTGMR 232 LR+F G P G P+ L + + GK V+ G R Sbjct: 174 TGLRFFTVYG----------PWGRPDMALFKFTKAMLEGKSID--VYN------YGKMKR 215 Query: 233 DYIHVMDLAEGHVAAMQA---------------KSNVAGTHLLNLGSGRASSVLEIIRAF 277 D+ ++ D+AE + +++A + N+G+ +++ I+A Sbjct: 216 DFTYIDDIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQAL 275 Query: 278 EAASGLTIPYEVKPRRAGDLACFYADPSYTKAQIGWQTQRDLTQMMEDSWRW 329 E A G+ + P + GD+ AD IG+ + + +++ W Sbjct: 276 EDALGIEAKKNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNW 327
>PF05704#Capsular polysaccharide synthesis protein Length = 307 Score = 26.0 bits (57), Expect = 0.016 Identities = 10/37 (27%), Positives = 19/37 (51%), Gaps = 1/37 (2%) Query: 44 WYQFFENMPEAVAKE-KTMKKWRREWKIKLIEEQNTE 79 W Q E P V + ++KK ++K+ +I+ N + Sbjct: 75 WLQGIEKAPYIVQQCVASVKKNSGDFKVIIIDGNNYK 111
>SECA#SecA protein signature. Length = 901 Score = 25.6 bits (56), Expect = 0.046 Identities = 13/28 (46%), Positives = 19/28 (67%), Gaps = 3/28 (10%) Query: 80 DVE-IVKNGQEYKVVVDARTGRVISSRR 106 DV+ IVK+G+ ++VD TGR + RR Sbjct: 323 DVDYIVKDGE--VIIVDEHTGRTMQGRR 348
>PF01540#Adhesin lipoprotein Length = 475 Score = 28.9 bits (64), Expect = 0.019 Identities = 27/115 (23%), Positives = 52/115 (45%), Gaps = 27/115 (23%) Query: 112 LARLAAAVDMAAADSKDVANSHIFDAMVNQKIKLQNPEVLKKWLGEQTAFDGKKVLAAYE 171 +++L+AAV+ A ++ + V ++ A N KIK + + L K Sbjct: 92 ISKLSAAVENAKSEQQKVDQANKKIADENLKIK-EGAKELLKL----------------- 133 Query: 172 SPESQARADKMQELTETFQIDGTPTVIVGGKYKVEFADWESGMNTIDLLADKVRE 226 ++K+Q +T I T T + G K++++ + ++TI+LL K E Sbjct: 134 -------SEKIQSFADT--IALTITKLEGKKFQIDETFKKQLISTIELLNKKSAE 179
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 30.9 bits (70), Expect = 0.010 Identities = 28/142 (19%), Positives = 53/142 (37%), Gaps = 4/142 (2%) Query: 179 FVITSLFMLPGLLMTLFLAREPVLPPAVPKTLKQTVVEPFKEFFTRKGIASAVCVLLFIF 238 F + L FL E + L++ + P F +G+ ++ F Sbjct: 163 FFAAAALNGLNFLTGCFLLPESH--KGERRPLRREALNPLASFRWARGMTVVAALMAVFF 220 Query: 239 LYKLGDSMATALATPFYLD-MGFSKTDIGLIAKNAGLWPAVAAGILGGVWMLKIGVNKAL 297 + +L + AL F D + T IG+ G+ ++A ++ G ++G +AL Sbjct: 221 IMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRAL 280 Query: 298 WLFGAVQAVTVLGFVWLAGFGP 319 + G + T + A G Sbjct: 281 -MLGMIADGTGYILLAFATRGW 301
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 29.8 bits (67), Expect = 0.033 Identities = 16/57 (28%), Positives = 24/57 (42%), Gaps = 3/57 (5%) Query: 70 IKIGYLPQEPELDPEKTVREEVESGLGEVAAAQKRLEEVYAEYANPD---ADFDALA 123 + +GYL Q + + +R E GL ++ Y Y +P ADF LA Sbjct: 464 VSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVSTPADFRMLA 520
>PF06580#Sensor histidine kinase Length = 349 Score = 26.0 bits (57), Expect = 0.040 Identities = 6/44 (13%), Positives = 16/44 (36%) Query: 38 VVSFSVCFWALSMTLKTMPLATAYAIWAGVGLVLTALVSVVFFG 81 ++ S+ L+ ++ + ++L L + V G Sbjct: 45 NIAISLMGLVLTHAYRSFIKRQGWLKLNMGQIILRVLPACVVIG 88
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 30.6 bits (69), Expect = 0.008 Identities = 12/39 (30%), Positives = 21/39 (53%), Gaps = 4/39 (10%) Query: 174 RFQGREGRLKILVVGGSLGADVLNKTVPQALALLPDNAR 212 ++Q G K++++G S GA+V+ P L +P R Sbjct: 109 KYQAEFGTQKVILIGYSFGAEVI----PFVLNEMPARYR 143
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 61.7 bits (150), Expect = 1e-12 Identities = 48/206 (23%), Positives = 88/206 (42%), Gaps = 22/206 (10%) Query: 163 STAVQN--VQKCIERCGLKSDQIMLQPLASGQAVLTEDEKDLGVCVIDIGGGTTDIAVYM 220 +T V+ +++ + G + ++ +P+A+ + G V+DIGGGTT++AV Sbjct: 118 ATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVIS 177 Query: 221 NGAIRHTSVIPAGGNLITKDLSKSLR------TPLDAAEYIKIHYGVASCDTEGLGEMIE 274 + ++S + GG+ + + +R AE IK G A E IE Sbjct: 178 LNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDE--VREIE 235 Query: 275 VPGV-----GDRTSRQVSSKVLAAIISARIQEIFGVVLGELQKSGFPKE----VLNAGIV 325 V G R S+++L A+ + I V+ L++ P E + G+V Sbjct: 236 VRGRNLAEGVPRGFTLNSNEILEALQEP-LTGIVSAVMVALEQC--PPELASDISERGMV 292 Query: 326 LTGGVSMMTGIVEFAEKIFDLPVRTG 351 LTGG +++ + + +PV Sbjct: 293 LTGGGALLRNLDRLLMEETGIPVVVA 318
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 477 bits (1230), Expect = e-171 Identities = 197/400 (49%), Positives = 256/400 (64%), Gaps = 9/400 (2%) Query: 6 ILVLNCGSSSLKGAVIDRKSGSVVLSCLGERLTTPEAVITFNKDGNKRQVPLSGRNCHAG 65 ILV+NCGSSSLK +I+ K G+V+ L ER+ ++++T N +G K ++ ++ H Sbjct: 3 ILVINCGSSSLKYQLIESKDGNVLAKGLAERIGINDSLLTHNANGEKIKIKKDMKD-HKD 61 Query: 66 AVGMLLNELEKHGLH-----DRIKAIGHRIAHGGEKYSESVLIDQAVMDELNACIPLAPL 120 A+ ++L+ L I A+GHR+ HGGE ++ SVLI V+ + CI LAPL Sbjct: 62 AIKLVLDALVNSDYGVIKDMSEIDAVGHRVVHGGEYFTSSVLITDDVLKAITDCIELAPL 121 Query: 121 HNPANISGILAAQEHFPGLPNVGVMDTSFHQTMPERAYTYAVPRELRKKYAFRRYGFHGT 180 HNPANI GI A + P +P V V DT+FHQTMP+ AY Y +P E KY R+YGFHGT Sbjct: 122 HNPANIEGIKACTQIMPDVPMVAVFDTAFHQTMPDYAYLYPIPYEYYTKYKIRKYGFHGT 181 Query: 181 SMRYVAPEAARILGKPLEDIRMIIAHLGNGASITAIKNGKSVDTSMGFTPIEGLVMGTRC 240 S +YV+ AA IL KP+E +++I HLGNG+SI A+KNGKS+DTSMGFTP+EGL MGTR Sbjct: 182 SHKYVSQRAAEILNKPIESLKIITCHLGNGSSIAAVKNGKSIDTSMGFTPLEGLAMGTRS 241 Query: 241 GDIDPGVYSYLTSHAGMDVAQVDEMLNKKSGLLGISELSNDCRTLEIAA-DEGHEGARLA 299 G IDP + SYL + +V +LNKKSG+ GIS +S+D R LE AA G + A+LA Sbjct: 242 GSIDPSIISYLMEKENISAEEVVNILNKKSGVYGISGISSDFRDLEDAAFKNGDKRAQLA 301 Query: 300 LEVMTYRLAKYIASMAVGCGGVDALVFTGGIGENSRNIRAKTVSYLDFLGLHIDTKANME 359 L V YR+ K I S A GGVD +VFT GIGEN IR + L+FLG +D + N Sbjct: 302 LNVFAYRVKKTIGSYAAAMGGVDVIVFTAGIGENGPEIREFILDGLEFLGFKLDKEKN-- 359 Query: 360 KRYGNSGIISPTDSSPAVLVVPTNEELMIACDTAELAGIL 399 K G IIS DS V+VVPTNEE MIA DT ++ L Sbjct: 360 KVRGEEAIISTADSKVNVMVVPTNEEYMIAKDTEKIVESL 399
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 30.7 bits (69), Expect = 0.004 Identities = 21/74 (28%), Positives = 34/74 (45%), Gaps = 4/74 (5%) Query: 154 GGPIIQTDPSKPPYHESHSISSVGLGVIAGVGFDITPKLTLDTGYRY-HNWGRLE--NTR 210 GG + + D Y ++H + GV + ITP++ Y++ +N G TR Sbjct: 119 GGMVWRADTKSNVYGKNHDTGVSPVFA-GGVEYAITPEIATRLEYQWTNNIGDAHTIGTR 177 Query: 211 FKTHEVSLGMRYRF 224 +SLG+ YRF Sbjct: 178 PDNGMLSLGVSYRF 191
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 47.9 bits (114), Expect = 4e-08 Identities = 66/335 (19%), Positives = 113/335 (33%), Gaps = 31/335 (9%) Query: 54 LSLFMFGTAFGQVVGGSVSDIKGRKPVALTGLIVYCLAVAAIVFVSSAEQLLNLRVVQAF 113 L+L+ V G++SD GR+PV L L + A + L R+V Sbjct: 49 LALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGI 108 Query: 114 GAGMTVVIVGAMVRDYYSGRKAAQMFALIGIILMVVPLVAPMVGALLQGLGGWQAIFVFL 173 G T + GA + D G + A+ F + + P++G L+ G A F Sbjct: 109 -TGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSP-HAPFFAA 166 Query: 174 AAYSLVLLGLVQYFLPKPAVGGKIG--RDVFGLVAG-RFKRVLKTRAAMGYLFFQAFSFG 230 AA + + + LP+ G + R+ +A R+ R + AA+ +FF G Sbjct: 167 AALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVG 226 Query: 231 SMFAFL----TESSFVYQQLYRVTPHQYAWAFALNIITMMFFNRVTAWRLKTGVHPQSIL 286 + A L E F + + A I + + + + L Sbjct: 227 QVPAALWVIFGEDRFHW------DATTIGISLAAFGILHSLAQAMITGPVAARLGERRAL 280 Query: 287 LWGIVVQFAANLSQLAAVLFFG-----LPPFWLLVACVMFSVGTQGLVGANTQACFMSYF 341 + G A+ + + F P LL + + Q ++ Sbjct: 281 MLG----MIADGTGYILLAFATRGWMAFPIMVLLASGGIGMPALQAMLSRQVD------- 329 Query: 342 KEEGGSANAVLGVFQSLIGAGVGMAATFLHDGSAT 376 +E G L SL + T ++ S T Sbjct: 330 EERQGQLQGSLAALTSLTSIVGPLLFTAIYAASIT 364
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 34.4 bits (79), Expect = 7e-04 Identities = 18/73 (24%), Positives = 29/73 (39%), Gaps = 11/73 (15%) Query: 50 PDLVLADTDAEG--GFELWKELAERYKDIPVAVCS-EKVPDSEV--------PYLPKPIR 98 DLV+ D F+L + + D+PV V S + + + YLPKP Sbjct: 48 GDLVVTDVVMPDENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFD 107 Query: 99 FETLFPMLRKLLQ 111 L ++ + L Sbjct: 108 LTELIGIIGRALA 120
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 28.7 bits (64), Expect = 0.013 Identities = 41/144 (28%), Positives = 62/144 (43%), Gaps = 39/144 (27%) Query: 12 VGVGKTT----------AIAAIS--DEALVQTDASASDMTLDRKRNTTVAMDYGAISLD- 58 V GKTT AI + D+ +TD + L+R+R T+ G S Sbjct: 12 VDAGKTTLTESLLYNSGAITELGSVDKGTTRTD----NTLLERQRGITIQT--GITSFQW 65 Query: 59 EDTKVHLYGTPGQERFNFMWEILSQGSM--GLVLLLD-----NARTNPLKDLEFFLHSFR 111 E+TKV++ TPG +F+ E+ S+ G +LL+ A+T H+ R Sbjct: 66 ENTKVNIIDTPGH--MDFLAEVYRSLSVLDGAILLISAKDGVQAQT------RILFHALR 117 Query: 112 GLLEKAPVVVGITKMDIRSQPGID 135 + P + I K+D Q GID Sbjct: 118 KM--GIPTIFFINKID---QNGID 136
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 149 bits (378), Expect = 4e-46 Identities = 72/108 (66%), Positives = 81/108 (75%), Gaps = 7/108 (6%) Query: 23 GQGAKIHKFVPKNSKTYSSDLIKTVDLTHIPTGAKA--RINAKITASVSRAGVLAGVGKL 80 G+G I+ Y D +++ TGA++ ++ K TASVSRAGVLAGVGKL Sbjct: 20 GEGGGIYTEY-----NYKFDKSLNLNVLESSTGARSLEKVPVKFTASVSRAGVLAGVGKL 74 Query: 81 ARLGAKFSTRAVPYVGTALLAHDVYETFKEDIQARGYQYDPETDKFAK 128 ARLGAKFSTRAVPYVGTALLAHDVYETFKEDIQARGYQYDPETDKF K Sbjct: 75 ARLGAKFSTRAVPYVGTALLAHDVYETFKEDIQARGYQYDPETDKFVK 122
>PF05860#haemagglutination activity domain. Length = 117 Score = 89.9 bits (223), Expect = 6e-23 Identities = 19/139 (13%), Positives = 46/139 (33%), Gaps = 24/139 (17%) Query: 81 IVADKSAPAQQQPTILQTGNGIPQVNIQTPTSAGVSVNQYAQFDVGNRGAILNNSRSNTQ 140 I D + P + + T + T + + + + +F V G N+ +N Q Sbjct: 3 ITPDTTLPIN---SNITTEGNTRIIERGTQAGSNLFHS-FQEFSVPTSGTAFFNNPTNIQ 58 Query: 141 TQLGGWIQGNPWLARGEARVVVNQINSSHSSQLNGYIEVGGRRAEVVIANPAGIAVNGGG 200 +++++ S ++G I A + + NP GI Sbjct: 59 -------------------NIISRVTGGSVSNIDGLIRANAT-ANLFLINPNGIIFGQNA 98 Query: 201 FINASRATLTTAQPQYQAG 219 ++ + + + + + Sbjct: 99 RLDIGGSFVGSTANRLKFA 117
>PF05860#haemagglutination activity domain. Length = 117 Score = 99.9 bits (249), Expect = 1e-26 Identities = 30/128 (23%), Positives = 55/128 (42%), Gaps = 14/128 (10%) Query: 73 AQITTDKSAPKNQQVVILKTNTGAPLVNIQTPNGRGLSHNRYTQFDVDNKGAVLNNDRNN 132 AQIT D + P N + T ++ T G L H+ + +F V G N+ Sbjct: 1 AQITPDTTLPINSNIT---TEGNTRIIERGTQAGSNLFHS-FQEFSVPTSGTAFFNNP-- 54 Query: 133 NPFVVKGSAQLILNEVRG-TASKLNGIVTVGGQKADVIIANPNGITVNGGGFKNVGRGIL 191 + Q I++ V G + S ++G++ A++ + NPNGI ++G + Sbjct: 55 ------TNIQNIISRVTGGSVSNIDGLIRANAT-ANLFLINPNGIIFGQNARLDIGGSFV 107 Query: 192 TTGAPQIG 199 + A ++ Sbjct: 108 GSTANRLK 115
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 73.6 bits (180), Expect = 2e-15 Identities = 56/353 (15%), Positives = 125/353 (35%), Gaps = 7/353 (1%) Query: 172 KYKERRKETEGRLKDTREHLQRLGDLQNELARQVEKLEKQAETAERYKSLTAQLNQQQDL 231 K++ + + D + + L D +EL ++ +++ ++ S A Q+ + Sbjct: 61 KFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEA 120 Query: 232 LDYA---QWRQSLAAADKATAQHQSLQAQQDETAAQVQALNDEVHALQTAEQSQQQAVHE 288 ++ + +A+ ++L+A++ AA+ L + + + Sbjct: 121 RKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKT 180 Query: 289 LSNKRGVLREQIARLEEQIRHQQNLHQRIERDKQAAQAQLQRIHQEQQQIRVQLEENELQ 348 L ++ L + A LE+ + N + +A+ + + + LE Sbjct: 181 LEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNF 240 Query: 349 VEEKQTELAEWAMQVAEHEERLPELEEAQATLNAAFQTQQDEANRIRRELALKQQQLAHA 408 ++ + A E R ELE+A + + E A + + A Sbjct: 241 STADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADL 300 Query: 409 EQTIAKHEERKGRLKQENQALNLPDEAETAAAQEAAALLQSQQEHYEEQIIAAEEALHAA 468 E + L+++ A + L+ Q + E + L A+ Sbjct: 301 EHQSQVLNANRQSLRRDLDA----SREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDAS 356 Query: 469 REAFQTASNRFQSLKQQHITLQAQQQALSQILSQQQEAADFWQATDHAAAPQL 521 REA + Q L++Q+ +A +Q+L + L +EA + A +L Sbjct: 357 REAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKL 409 Score = 44.3 bits (104), Expect = 2e-06 Identities = 54/335 (16%), Positives = 115/335 (34%), Gaps = 32/335 (9%) Query: 171 SKYKERRKETEGRLKDTREHLQRLGDLQNELARQVEKLEKQAETAERYKSLTAQLNQQQD 230 + R+ + E L+ L + LE + E+ + Sbjct: 151 AALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADS 210 Query: 231 LLDYAQWRQSLAAADKATAQHQSLQAQQDETAAQVQALNDEVHALQTAEQSQQQAVHELS 290 A A+ +L A++ + ++ + A + L Sbjct: 211 -----------AKIKTLEAEKAALAARKADLEKALEGAMNFSTAD-------SAKIKTLE 252 Query: 291 NKRGVLREQIARLEEQIRHQQNLHQRIERDKQAAQAQLQRIHQEQQQIRVQLEENELQVE 350 ++ L + A LE+ + N + +A+ + E+ + Q + + Sbjct: 253 AEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQ 312 Query: 351 EKQTELAEWAMQVAEHEERLPELEEAQATLNAAFQTQQDEANRIRRELALKQQQLAHAEQ 410 + +L + E +LEE A+ Q +RR+L ++ E Sbjct: 313 SLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQ-------SLRRDLDASREAKKQLEA 365 Query: 411 TIAKHEERKGRLKQENQALNLPDEAETAAAQEAAALLQSQQEHYEEQIIAAEEALHAARE 470 K EE+ + Q+L + A++EA ++ E + +AA E L+ E Sbjct: 366 EHQKLEEQNKISEASRQSLR----RDLDASREAKKQVEKALEEANSK-LAALEKLNKELE 420 Query: 471 AFQTASNRFQSLKQQHITLQAQQQALSQILSQQQE 505 + + + ++ Q L+A+ +AL + L++Q E Sbjct: 421 ESKKLTEKEKAELQAK--LEAEAKALKEKLAKQAE 453 Score = 43.5 bits (102), Expect = 4e-06 Identities = 54/298 (18%), Positives = 109/298 (36%), Gaps = 15/298 (5%) Query: 642 YAKPAQESLIAQKARLDGIASELENLAPELSAAEAAFKQAEAAVRSSEVQHKNLMQQQQQ 701 ++ + +A +A+ +L L A A +++ E + L +Q + Sbjct: 135 FSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAE 194 Query: 702 HTRQYSQAQQRAAELLARTNQGQIRREHIERELAQLAEEQTVLQHTSDGLSDDIVTLQEA 761 + A + A+ + + + A L + + S S I TL+ Sbjct: 195 LEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAE 254 Query: 762 AAELEHQQQTTAHSRQEQQGRLKQAQLALLEANRQYGLAEVAVHKLNQQKQNYRQQIAQL 821 A LE +Q + + + + E L Q Q Sbjct: 255 KAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANR--- 311 Query: 822 EQQTLDWQERQQELALAYETEFQNDEQHIKLEELSEAVQTLDEEYIVVQEKLAQIQEQGR 881 Q +++L + E + Q + +H KLEE + + + ++ L +E + Sbjct: 312 -------QSLRRDLDASREAKKQLEAEHQKLEEQN---KISEASRQSLRRDLDASREAKK 361 Query: 882 EQYAKVQTLQTKLPQLQAATQTALLQQQEALINAKRYHQ-NLTERAADLDALEALAKE 938 + A+ Q L+ + ++ A++ +L + +A AK+ + L E + L ALE L KE Sbjct: 362 QLEAEHQKLE-EQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKE 418 Score = 40.4 bits (94), Expect = 4e-05 Identities = 47/288 (16%), Positives = 109/288 (37%), Gaps = 18/288 (6%) Query: 165 EEAAGVSKYKERRKETEGRLKDTREHLQRLGDLQNELARQVEKLEKQAETAERYKSLTAQ 224 ++A + + + E R + + L+ + + +++ LE + K+ + Sbjct: 173 ADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEK 232 Query: 225 LNQQQDLLDYAQWRQSLAAADKATAQHQSLQAQQDETAAQVQALNDEVHALQTAEQSQQQ 284 + + +A+ ++L+A++ A+ L + + Sbjct: 233 ALEGAM-----------NFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSA 281 Query: 285 AVHELSNKRGVLREQIARLEEQIRHQQNLHQRIERDKQAAQAQLQRIHQEQQQIRVQLEE 344 + L ++ L + A LE Q + Q + RD A++ +++ E Q++ Q + Sbjct: 282 KIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKI 341 Query: 345 NELQVEEKQTELAEWAMQVAEHEERLPELEE-------AQATLNAAFQTQQDEANRIRRE 397 +E + + +L + E +LEE ++ +L ++ ++ + Sbjct: 342 SEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKA 401 Query: 398 LALKQQQLAHAEQTIAKHEERKGRLKQENQALNLPDEAETAAAQEAAA 445 L +LA E+ + EE K ++E L EAE A +E A Sbjct: 402 LEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEKLA 449 Score = 37.0 bits (85), Expect = 4e-04 Identities = 40/249 (16%), Positives = 79/249 (31%), Gaps = 25/249 (10%) Query: 733 ELAQLAEEQTVLQHTSDGLSDDIVTLQEAAAELEHQQQTTAHSRQEQQGRLKQAQLALLE 792 + + L+ L+ +D L++++ +E + + A QE + R + AL Sbjct: 72 KNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEG 131 Query: 793 ANRQYGLAEVAVHKLNQQKQNYRQQIAQLEQQ-------------------------TLD 827 A + L +K + A LE+ Sbjct: 132 AMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEAR 191 Query: 828 WQERQQELALAYETEFQNDEQHIKLEELSEAVQTLDEEYIVVQEKLAQIQEQGREQYAKV 887 E ++ L A + + LE A+ + E + + Sbjct: 192 QAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTL 251 Query: 888 QTLQTKLPQLQAATQTALLQQQEALINAKRYHQNLTERAADLDALEALAKESPKVLNSSI 947 + + L QA + AL + L A L+A +A + +VLN++ Sbjct: 252 EAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANR 311 Query: 948 GSLSQQIEA 956 SL + ++A Sbjct: 312 QSLRRDLDA 320
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 39.1 bits (91), Expect = 7e-07 Identities = 14/64 (21%), Positives = 31/64 (48%) Query: 3 NVQKGFTLLELMIAVAILGILTLITYPSYKTYIRRVRLSEVRTTLLHNAQTMERYYRQKG 62 + Q+GFTLLE+M+ + I+G+L + P+ + + + ++ ++ Y Sbjct: 5 DKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDNH 64 Query: 63 TFKT 66 + T Sbjct: 65 HYPT 68
>CHANNELTSX#Nucleoside-specific channel-forming protein Tsx signature. Length = 294 Score = 26.9 bits (59), Expect = 0.034 Identities = 16/33 (48%), Positives = 18/33 (54%) Query: 1 MKKTLLAIVAVSALSACRQAEEGPPPLPRQISD 33 MKKTLLA AV ALS A P+ +SD Sbjct: 1 MKKTLLAAGAVVALSTTFAAGAAENDKPQYLSD 33
>CABNDNGRPT#NodO calcium binding signature. Length = 479 Score = 151 bits (383), Expect = 7e-41 Identities = 60/260 (23%), Positives = 91/260 (35%), Gaps = 33/260 (12%) Query: 1029 SGQVTVQSYFQNDGSGAYRIDEIHFDNGKVLD-VATVKEL--VQQSTDGSDRLYAYQSGN 1085 S Q ++ SY+ + +GA H+ ++D +A ++ L +T D +Y + S Sbjct: 220 SYQFSIMSYWGENETGADY--NGHYGGAPMIDDIAAIQRLYGANMTTRTGDSVYGFNSNT 277 Query: 1086 ---TLNGGLGDDYLYGADGD-------------------------DLLNGDAGNDSIYSG 1117 L + D + G GN SI G Sbjct: 278 DRDFYTATDSSKALIFSVWDAGGTDTFDFSGYSNNQRINLNEGSFSDVGGLKGNVSIAHG 337 Query: 1118 NGNDTLDGGEGNDALYGYNGNDALNGGEGNDHLNGEDGNDTLIGGAGNDYLEGGSGSDTY 1177 + GG GND L G + ++ L GG GND L G G DTL GGAG D GSG D+ Sbjct: 338 VTIENAIGGSGNDILVGNSADNILQGGAGNDVLYGGAGADTLYGGAGRDTFVYGSGQDST 397 Query: 1178 VFGEGFGQDTVYNYHVDKNSDTMHFKGFKAADVHFIRSGSDLVLSASEQDNVRISGFFYG 1237 V + D S + F G +++L +++ Sbjct: 398 VAAYDWIADFQKGIDKIDLSAFRNEGQLSFVQDQFTGKGQEVMLQWDAANSITNLWLHEA 457 Query: 1238 ENHRVDTFVFDDAAISNPDF 1257 + VD V + D Sbjct: 458 GHSSVDFLVRIVGQAAQSDI 477 Score = 137 bits (346), Expect = 4e-36 Identities = 58/252 (23%), Positives = 92/252 (36%), Gaps = 35/252 (13%) Query: 829 SGQVTVQSYFQNDGSGAYRIDEIHFDNGKVLD-VATVKEL--VQQSTDGSDRLYAYQSGN 885 S Q ++ SY+ + +GA H+ ++D +A ++ L +T D +Y + S Sbjct: 220 SYQFSIMSYWGENETGADY--NGHYGGAPMIDDIAAIQRLYGANMTTRTGDSVYGFNSNT 277 Query: 886 ---TLNGGLGDDYLYGADGD-------------------------DLLNGDAGNDSIYSG 917 L + D + G GN SI G Sbjct: 278 DRDFYTATDSSKALIFSVWDAGGTDTFDFSGYSNNQRINLNEGSFSDVGGLKGNVSIAHG 337 Query: 918 NGNDTLDGGEGNDALYGYNGNDALNGGEGNDHLNGEDGNDTLIGGAGNDYLEGGSGSDTY 977 + GG GND L G + ++ L GG GND L G G DTL GGAG D GSG D+ Sbjct: 338 VTIENAIGGSGNDILVGNSADNILQGGAGNDVLYGGAGADTLYGGAGRDTFVYGSGQDST 397 Query: 978 VFGKGFGQDAVYNYDYATGRKDIIRFTDGITADMLTFTREGNHLLIKAKDGSGQVTVQSY 1037 V + D D R ++ FT +G ++++ + + + Sbjct: 398 VAAYDWIADFQKGIDKID--LSAFRNEGQLSFVQDQFTGKGQEVMLQWDAANSITNLWLH 455 Query: 1038 FQNDGSGAYRID 1049 S + + Sbjct: 456 EAGHSSVDFLVR 467 Score = 75.4 bits (185), Expect = 5e-16 Identities = 32/127 (25%), Positives = 56/127 (44%), Gaps = 11/127 (8%) Query: 730 GTQADDILQNVGFGHNKNVSLYGNDGNDTLIGGAGNDYLEGGSGSDTYVFGEG-----FG 784 G +DIL G++ + L G GND L GGAG D L GG+G DT+V+G G Sbjct: 345 GGSGNDIL----VGNSADNILQGGAGNDVLYGGAGADTLYGGAGRDTFVYGSGQDSTVAA 400 Query: 785 QDTVYNYDYATGRKDIIRFT--DGITADMLTFTREGNHLLIKAKDGSGQVTVQSYFQNDG 842 D + ++ + D+ F ++ FT +G ++++ + + + Sbjct: 401 YDWIADFQKGIDKIDLSAFRNEGQLSFVQDQFTGKGQEVMLQWDAANSITNLWLHEAGHS 460 Query: 843 SGAYRID 849 S + + Sbjct: 461 SVDFLVR 467 Score = 46.9 bits (111), Expect = 4e-07 Identities = 33/244 (13%), Positives = 55/244 (22%), Gaps = 67/244 (27%) Query: 741 GFGHNKNVSLYGNDGNDTLIGGAGNDYLEG----GSGSDTYVFGEGFGQDTVY----NYD 792 + N D + L G+DT+ F + ++ Sbjct: 264 TRTGDSVYGFNSNTDRDFYTATDSSKALIFSVWDAGGTDTFDFSGYSNNQRINLNEGSFS 323 Query: 793 YATGRKDIIRFTDGITADMLTFTREGNHLLIKAKDGSGQVTVQSYFQNDGSGAYRIDEIH 852 G K + G+T + GN +L+ Sbjct: 324 DVGGLKGNVSIAHGVTIENAIGG-SGNDILV----------------------------- 353 Query: 853 FDNGKVLDVATVKELVQQSTDGSDRLYAYQSGNTLNGGLGDDYLYGADGDDLLNGDAGND 912 + L + L GG G D LYG G D +G D Sbjct: 354 ------------------GNSADNILQGGAGNDVLYGGAGADTLYGGAGRDTFVYGSGQD 395 Query: 913 SIYSGNGNDTLDGGEGNDALYGYNGNDALNGGEGNDHLNGEDGNDTLIGGAGNDYLEGGS 972 S + D G + D G G + + Sbjct: 396 STVAAYDW-------IADFQKGIDKIDLSAFRNEGQ----LSFVQDQFTGKGQEVMLQWD 444 Query: 973 GSDT 976 +++ Sbjct: 445 AANS 448
>adhesinb#Adhesin B signature. Length = 310 Score = 222 bits (567), Expect = 2e-73 Identities = 79/325 (24%), Positives = 150/325 (46%), Gaps = 36/325 (11%) Query: 1 MKHLKLTLIAALLTASATA------------APLPVVTSFSILGDVAKQIGGERVSIQSL 48 MK + ++ L A + L VV + SI+ D+ K I G+++++ S+ Sbjct: 1 MKKCRFLVLLLLAFVGLAACSSQKSSTETGSSKLNVVATNSIIADITKNIAGDKINLHSI 60 Query: 49 VGANQDTHAYHMTSGDIKKIRSAKLVLLNGLGLEAAD-------VQRAVKQSKVSYTEAT 101 V QD H Y D+KK A L+ NG+ LE V+ A K+ Y + Sbjct: 61 VPVGQDPHEYEPLPEDVKKTSQADLIFYNGINLETGGNAWFTKLVENAKKKENKDYYAVS 120 Query: 102 KGIQPLKAEEEGGHHHDHDHDHEGHHHDHGEYDPHVWNDPVLMSAYAQNVAKALIKADPE 161 +G+ + E +G DPH W + YAQN+AK L + DP Sbjct: 121 EGVDVIYLEG---------QSEKGKE------DPHAWLNLENGIIYAQNIAKRLSEKDPA 165 Query: 162 GKVYYQQRLGNYQMQLKKLHSDAQAAFNAVPAAKRKVLTGHDAFSYMGKRYHIEFIAPQG 221 K Y++ L Y +L L +A+ FN +P K+ ++T F Y K Y++ Sbjct: 166 NKETYEKNLKAYVEKLSALDKEAKEKFNNIPGEKKMIVTSEGCFKYFSKAYNVPSAYIWE 225 Query: 222 VSSEAEPSAKQVAAIIRQIKREGIKAVFTENIKDTRMVDRIAKETGVNVSGKLYSDALG- 280 +++E E + Q+ ++ ++++ + ++F E+ D R + ++K+T + + K+++D++ Sbjct: 226 INTEEEGTPDQIKTLVEKLRKTKVPSLFVESSVDDRPMKTVSKDTNIPIYAKIFTDSVAE 285 Query: 281 -NAPADTYIGMYRHNIKALTNAMKQ 304 D+Y M ++N++ + + + Sbjct: 286 KGEEGDSYYSMMKYNLEKIAEGLSK 310
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.017 Identities = 9/18 (50%), Positives = 12/18 (66%) Query: 45 GPNGAGKSTFLKSLMGLQ 62 G G GKST + +L+GL Sbjct: 603 GTGGIGKSTLINTLVGLD 620
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 33.0 bits (75), Expect = 0.003 Identities = 11/59 (18%), Positives = 22/59 (37%) Query: 719 ITLAEHMRGSGLAQKMMELIIQTAAQQGYRTMSADILKTNTPMIKLAEKSGFTLKESDT 777 I +A+ R G+ ++ I+ A + + + + N K F + DT Sbjct: 95 IAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGAVDT 153
>PF06580#Sensor histidine kinase Length = 349 Score = 32.1 bits (73), Expect = 0.004 Identities = 17/99 (17%), Positives = 35/99 (35%), Gaps = 18/99 (18%) Query: 359 NVIRNAVNYSPEGSTILINIGQDHKHWIIDVTDNGPGVDEMQLPHIFTAFYRADSSANKP 418 N I++ + P+G IL+ +D+ ++V + G + K Sbjct: 266 NGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNT----------------KE 309 Query: 419 GTGLGLALTQHIIEQHCGKIIAENI--KPNGLRMRFILP 455 TG GL + ++ G + K + ++P Sbjct: 310 STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 92.2 bits (229), Expect = 7e-24 Identities = 37/120 (30%), Positives = 63/120 (52%), Gaps = 1/120 (0%) Query: 2 SRVLLVDDDALLTELLTEYLSAEGLNVRSVPDGEAGVQEILSGQYDVVVLDSMMPKMNGL 61 + +L+ DDDA + +L + LS G +VR + + I +G D+VV D +MP N Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 DVLKNVRAR-STVPIIMLTAKGDDIDRIIGLEMGADDYVPKPCTPRELLARINAILRRAQ 120 D+L ++ +P+++++A+ + I E GA DY+PKP EL+ I L + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123
>TATBPROTEIN#Bacterial sec-independent translocation TatB protein signature. Length = 171 Score = 152 bits (385), Expect = 6e-49 Identities = 39/165 (23%), Positives = 71/165 (43%), Gaps = 18/165 (10%) Query: 1 MFDFGLGELVFVGIIALIVLGPERLPEAARTAGRLIGRLQRFVGSVKQEFDTQIELEELR 60 MFD G EL+ V II L+VLGP+RLP A +T I L+ +V+ E +++L+E + Sbjct: 1 MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNELTQELKLQEFQ 60 Query: 61 KAKQEFEAAAAQVRDSLKETGTDMEGNLHDISDGLKPWEKLPEQRTPADFGVDENGNPLP 120 + ++ E A+ ++ L D L+ + ++ A + Sbjct: 61 DSLKKVEKASLT----------NLTPELKASMDELRQAAESMKRSYVA-----NDPEKAS 105 Query: 121 DAANTLSDGISDVMPSER---SYASAETLGDSGQTGSTAEPAETD 162 D A+T+ + + + + A+A+T S + P Sbjct: 106 DEAHTIHNPVVKDNEAAHEGVTPAAAQTQASSPEQKPETTPEPVV 150
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 88.7 bits (220), Expect = 3e-21 Identities = 48/183 (26%), Positives = 88/183 (48%), Gaps = 8/183 (4%) Query: 422 QIVEERTIGPSLGKENIEKGFHSTLWGFAIVAAFMVVYYRL---MGFFSTIALSANILFL 478 +I ++GP + E + S L A V ++ R + +AL ++L Sbjct: 136 KITSFESVGPKVSGELVWTAVWSLL--AATVVIMFYIWVRFEWQFALGAVVALVHDVLLT 193 Query: 479 IGILSAMQATLTLPGMAALALTLGMAIDSNVLINERIREELRA--GVPPQQAINLGFQHA 536 +G+ + +Q L +AAL G +I+ V++ +R+RE L +P + +NL Sbjct: 194 VGLFAVLQLKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRDVMNLSVNET 253 Query: 537 WATIVDSNLTSLIAGIALLVFGSGPVRGFAVVHCLGILTSMYSSVVVFRALVNLWYGRRR 596 + V + +T+L+A + +L++G +RGF G+ T YSSV V + +V L+ G R Sbjct: 254 LSRTVMTGMTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAKNIV-LFIGLDR 312 Query: 597 KLQ 599 + Sbjct: 313 NKE 315
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 329 bits (844), Expect = e-115 Identities = 107/320 (33%), Positives = 176/320 (55%), Gaps = 16/320 (5%) Query: 1 MELFKIKRDIPFMSYGKLTTFISLVTFIAAVFFLVTRGLNFSVEFTGGTVMEVQYQQGAD 60 ++L K + F + T ++V IA+V + GLNF ++F GGT + + D Sbjct: 5 LKLVPEKTNFDFFRWQWATFGAAIVMMIASVILPLVIGLNFGIDFKGGTTIRTESTTAID 64 Query: 61 VNKMRERLDTLKIGDVQVQALG------TNKHIMIRLPNKEGVTSAQ--------LSNQV 106 V R L+ L++GDV + + MIR+ +E A+ L N+V Sbjct: 65 VGVYRAALEPLELGDVIISEVRDPSFREDQHVAMIRIQMQEDGQGAEGQGAQGQELVNKV 124 Query: 107 MDLLKKDSPDVTLRQVEFIGPQVGEELVSNGLMALGFVVIGIIIYLSMRFEWRFAVSAII 166 L P + + E +GP+V ELV + +L + I+ Y+ +RFEW+FA+ A++ Sbjct: 125 ETALTAVDPALKITSFESVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGAVV 184 Query: 167 ANMHDIVIILGCFAFFQWEFSLTVLAGILAVLGYSVNESVVVFDRIRENFRKPAMRGHAV 226 A +HD+++ +G FA Q +F LT +A +L + GYS+N++VVVFDR+REN K + + Sbjct: 185 ALVHDVLLTVGLFAVLQLKFDLTTVAALLTITGYSINDTVVVFDRLRENLIK--YKTMPL 242 Query: 227 PEVIDNAITATMSRTIITHGSTEAMVVSMLVFGGAALHGFSMALTIGIVFGIYSSVLVAS 286 +V++ ++ T+SRT++T +T +V ML++GG + GF A+ G+ G YSSV VA Sbjct: 243 RDVMNLSVNETLSRTVMTGMTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAK 302 Query: 287 PLLLMFGLSRDNIGKEPKKK 306 ++L GL R+ K+P K Sbjct: 303 NIVLFIGLDRNKEKKDPSDK 322
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 209 bits (533), Expect = 3e-62 Identities = 115/456 (25%), Positives = 208/456 (45%), Gaps = 47/456 (10%) Query: 11 RRRTFAIISHPDAGKTTLTEKLLLFSGAIQSAGTVKGKKTGKFATSDWMEIEKQRGISVA 70 + +++H DAGKTTLTE LL SGAI G+V T +D +E+QRGI++ Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTT----RTDNTLLERQRGITIQ 57 Query: 71 SSVMQFDYKDHTVNLLDTPGHQDFSEDTYRVLTAVDSALMVIDAAKGVEAQTIKLLNVCR 130 + + F +++ VN++DTPGH DF + YR L+ +D A+++I A GV+AQT L + R Sbjct: 58 TGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALR 117 Query: 131 LRDTPIVTFMNKYDREVRDSLELLDEVENILKIRCAPVTWPIGMGKNFKGVYHILNDEIY 190 P + F+NK D+ D + +++ L + + N +++ Sbjct: 118 KMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQ-KVELYPNMCVTNFTESEQWD 176 Query: 191 LFEAGGERLPHEFDIIKGIDNPELEQRFPLEIQQLRDEIELVQAASNEFNLDEFLAGELT 250 G + L + K + LE LE++Q +E S L Sbjct: 177 TVIEGNDDL-----LEKYMSGKSLE---ALELEQ--EESIRFHNCS------------LF 214 Query: 251 PVFFGSAINNFGIQEILNSLIDWAPAPKPRDATVRMVEPDEPKFSGFIFKIQANMDPKHR 310 PV+ GSA NN GI ++ + + + R + + G +FKI+ K R Sbjct: 215 PVYHGSAKNNIGIDNLIEVITNKFYSSTHRGQS---------ELCGKVFKIE--YSEK-R 262 Query: 311 DRIAFLRVCSGKFERGMKMKHLRINR--EIAASSVVTFMSHDRELVEEAYAGDIIGIPNH 368 R+A++R+ SG +RI+ +I + + T ++ + +++AY+G+I+ + N Sbjct: 263 QRLAYIRLYSGVLHLRDS---VRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNE 319 Query: 369 GNIQIGDSFSEGEQLAFTGIPFFA-PELFRSVRIKNPLKIKQLQKGLQQLGEEG-AVQVF 426 +++ + + L P L +V P + + L L ++ + ++ + Sbjct: 320 F-LKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYY 378 Query: 427 KPMSGADLILGAVGVLQFEVVTSRLANEYGVEAVFD 462 + ++IL +G +Q EV + L +Y VE Sbjct: 379 VDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIK 414
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 500 bits (1289), Expect = e-175 Identities = 155/374 (41%), Positives = 217/374 (58%), Gaps = 25/374 (6%) Query: 12 SILAVCLPMHAHASDLANDSFIRQVLDRQHFEPDGKYHLFGS-RGELAERSGHIGLGKIQ 70 ++ A L A A+DLA D FI RQH+EP GKYHLFG RG +++R+G I + + Sbjct: 15 AVAAAALIQPALAADLAQDPFITDNAQRQHYEPGGKYHLFGDPRGSVSDRTGKINVIQDY 74 Query: 71 SHQLGNLMIQQAAIKGNIGYIVRFSDHGHEVHSPFDNHASHSDSDEAGSPVDGFSLYRIH 130 +HQ+GNL+IQQA I G IGY RFS HGHE H+PFDNHA+ S S+E G+ +GF++YR++ Sbjct: 75 THQMGNLLIQQANINGTIGYHTRFSGHGHEEHAPFDNHAADSASEEKGNVDEGFTVYRLN 134 Query: 131 WDGYEHHPADGYDGPQGGGYPAPKGARDIYSYDIKGVAQNIRLNLTDNRSTGQRLADRFH 190 W+G+EHHPAD YDGP+GG YP P GARD Y+Y + G A++I+LN TD RS QR++D + Sbjct: 135 WEGHEHHPADAYDGPKGGNYPKPTGARDEYTYHVNGTARSIKLNPTDTRSIRQRISDNYS 194 Query: 191 NAGSMLTQGVGDGFKRATRYSPELDRSGNAAEAFNGTADIVKNIIGAAGEIVGAGDAVQG 250 N GS + + ++ ++ +LDR GN+ E NG A N +AGE +G GD + G Sbjct: 195 NLGSNFSDRADEANRKMFEHNAKLDRWGNSMEFINGVAAGALNPFISAGEALGIGDILYG 254 Query: 251 ISEGSNIAVMHGLGLLSTENKMARINDLADMAQLKDYAAAAIRDWAVQNPNAAQGIEAVS 310 + A M + L E K A I L +A + A+ W +NPNAA+ +EAV Sbjct: 255 TRYAIDKAAMRNIAPLPAEGKFAVIGGLGSVAGFEKNTREAVDRWIQENPNAAETVEAVF 314 Query: 311 NIFMAAIPIKGIGAVRGKYGLGGITAHPIKRSQMGAIALPKGKSAVSDNFADAAYAKYPS 370 N+ AA K +++ A P GK+AVS +FAD+ K Sbjct: 315 NVAAAA-----------------------KVAKLAKAAKP-GKAAVSGDFADSYKKKLAL 350 Query: 371 PYHSRNIRSNLEQR 384 +R + N + R Sbjct: 351 SDSARQLYQNAKYR 364
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 563 bits (1451), Expect = 0.0 Identities = 301/420 (71%), Positives = 318/420 (75%), Gaps = 63/420 (15%) Query: 1 MKPLRRLTNLLAACAVAAAALIQPALAADLAQDPFITDNAQRQHYEPGGKYHLFGDPRGS 60 MKPLRRLTNLLAACAVAAAALIQPALAADLAQDPFITDNAQRQHYEPGGKYHLFGDPRGS Sbjct: 1 MKPLRRLTNLLAACAVAAAALIQPALAADLAQDPFITDNAQRQHYEPGGKYHLFGDPRGS 60 Query: 61 VSDRTGKINVIQDYTHQMGNLLIQQANINGTIGYHTRFSGHGHEEHAPFDNHAADSASEE 120 VSDRTGKINVIQDYTHQMGNLLIQQANINGTIGYHTRFSGHGHEEHAPFDNHAADSASEE Sbjct: 61 VSDRTGKINVIQDYTHQMGNLLIQQANINGTIGYHTRFSGHGHEEHAPFDNHAADSASEE 120 Query: 121 KGNVDEGFTVYRLNWEGHEHHPADAYDGPKGGNYPKPTGARDEYTYHVNGTARSIKLNPT 180 KGNVDEGFTVYRLNWEGHEHHPADAYDGPKGGNYPKPTGARDEYTYHVNGTARSIKLNPT Sbjct: 121 KGNVDEGFTVYRLNWEGHEHHPADAYDGPKGGNYPKPTGARDEYTYHVNGTARSIKLNPT 180 Query: 181 DTRSIRQRISDNYSNLGSNFSDRADEANRKMFEHNAKLDRWGNSMEFINGVAAGALNPFI 240 DTRSIRQRISDNYSNLGSNFSDRADEANRKMFEHNAKLDRWGNSMEFINGVAAGALNPFI Sbjct: 181 DTRSIRQRISDNYSNLGSNFSDRADEANRKMFEHNAKLDRWGNSMEFINGVAAGALNPFI 240 Query: 241 SAGE--------------------------------------------------AVDQWM 250 SAGE AVD+W+ Sbjct: 241 SAGEALGIGDILYGTRYAIDKAAMRNIAPLPAEGKFAVIGGLGSVAGFEKNTREAVDRWI 300 Query: 251 QENPNAAETVEALVNVLPFAKVKNLTKAAKPGKAAVSGDFSDSYKHNTASRLSQSVDGEM 310 QENPNAAETVEA+ NV AKV L KAAKPGKAAVSGDF+DSYK A LS S ++ Sbjct: 301 QENPNAAETVEAVFNVAAAAKVAKLAKAAKPGKAAVSGDFADSYKKKLA--LSDSAR-QL 357 Query: 311 FQTRN----VDFKAKSIGTKIHDGA----QGKHISGHRN--YIEGKSTLNQNINPQELLN 360 +Q +D + + + DG+ G+ I N I+ K T++ P+ LN Sbjct: 358 YQNAKYREALDIHYEDLIRRKTDGSSKFINGREIDAVTNDALIQAKRTISAIDKPKNFLN 417
>OUTRMMBRANEA#Outer membrane protein A signature. Length = 346 Score = 38.4 bits (89), Expect = 7e-06 Identities = 37/193 (19%), Positives = 64/193 (33%), Gaps = 21/193 (10%) Query: 1 MKKALATLIALALPAAALAEGA---SGFYVQADAAHAKASSSL-------GSAKGFSPRI 50 MKK + A +A+ A + +Y A ++ + Sbjct: 1 MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFINNNGPTHENQLGAGA 60 Query: 51 SAGYRIND---LRFAVDYTRYKNYKAPSTDFKLYSIGAS----AIYDFDTQSPVKPYLGA 103 GY++N D+ YK + + G Y + LG Sbjct: 61 FGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPITDDLDIYTRLGG 120 Query: 104 RLSLNRASVDLGGSDSFSQTSIGLGVLTGVSYAVTPNVDLDAGYRY-NYIGKVNTV-KNV 161 + ++ G + + S GV YA+TP + Y++ N IG +T+ Sbjct: 121 MVWRADTKSNVYGKNHDTGVSPVFAG--GVEYAITPEIATRLEYQWTNNIGDAHTIGTRP 178 Query: 162 RSGELSAGVRVKF 174 +G LS GV +F Sbjct: 179 DNGMLSLGVSYRF 191
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 37.5 bits (87), Expect = 3e-05 Identities = 11/23 (47%), Positives = 15/23 (65%) Query: 103 ELARACNVQHLIFTSSTSVYGDT 125 E R +QHL++ SS+SVYG Sbjct: 111 EGCRHNKIQHLLYASSSSVYGLN 133
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 68.1 bits (166), Expect = 2e-16 Identities = 18/75 (24%), Positives = 38/75 (50%) Query: 1 MPVTRPAKINTYTRIIDASLALFNEEGERNISTNHIAAHLGISPGNLYYHFRNKDEIIVQ 60 T+ T I+D +L LF+++G + S IA G++ G +Y+HF++K ++ + Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 61 LFKRYSEALLAYLNE 75 +++ + E Sbjct: 62 IWELSESNIGELELE 76
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 28.7 bits (64), Expect = 0.035 Identities = 13/56 (23%), Positives = 27/56 (48%), Gaps = 3/56 (5%) Query: 265 ILFGFLASLIVMWFSRQREYRADAGAAKLVGAPKMISALQRLKGNPVDLPEEMNAM 320 I+ F+ I+ + + +Y + A L PK+ + +RL + + +EM A+ Sbjct: 359 IIITFIVRGIMYPLT-KAQYTSMAKMRML--QPKIQAMRERLGDDKQRISQEMMAL 411
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 108 bits (272), Expect = 3e-29 Identities = 88/373 (23%), Positives = 142/373 (38%), Gaps = 83/373 (22%) Query: 1 MTIIVTGAAGFIGSNIVKALNQRGITDIVAVDNLS-------KGEKFKNLAECEIAHY-- 51 M +VTGAAGFIG ++ K L + G +V +DNL+ K + + LA+ + Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAG-HQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKI 59 Query: 52 -LDKHEFIRQVREHILPYQNIEAVFHQGACSDTMNHDGLYMMDNNYQY-------TLDLL 103 L E + + + E VF Y ++N + Y L++L Sbjct: 60 DLADREGMTDLFAS----GHFERVFISPHRLAVR-----YSLENPHAYADSNLTGFLNIL 110 Query: 104 DWCQDERIP-FLYASSAAVYGKGEI--FREERELEKPLNVYGYSKFLFDQVLRRRMKEGL 160 + C+ +I LYASS++VYG F + ++ P+++Y +K ++++ Sbjct: 111 EGCRHNKIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATK-KANELMAHTYSHLY 169 Query: 161 TAQVVGFRYFNVYGQHEQHKGRMASVAFHHFHQYREHGYVNLFGSNDGYGNGEQTRDFVS 220 G R+F VYG GR +A F + G S D Y G+ RDF Sbjct: 170 GLPATGLRFFTVYGP----WGR-PDMALFKFTKAMLEG-----KSIDVYNYGKMKRDFTY 219 Query: 221 VEDVAKVNLYFFDHPELSG------------------IYNLGTGRSQQFNELAAATVNAC 262 ++D+A+ + D + +YN+G + + + A Sbjct: 220 IDDIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDY----IQAL 275 Query: 263 RAAEGKPEMSLKELVEEELIRYIPFP--DALKGKYQSFTQADITKLREA-GYKEEFFDVK 319 A G E +P D L T AD L E G+ E VK Sbjct: 276 EDALGI----------EAKKNMLPLQPGDVL------ETSADTKALYEVIGFTPE-TTVK 318 Query: 320 SGVDRYVKWMLEN 332 GV +V W + Sbjct: 319 DGVKNFVNWYRDF 331
>SECA#SecA protein signature. Length = 901 Score = 29.1 bits (65), Expect = 0.023 Identities = 8/38 (21%), Positives = 22/38 (57%), Gaps = 1/38 (2%) Query: 82 LEEKVAEIQNNEARNVGRKEKQEL-KEQITDDLLPRAF 118 +E ++ ++ + E + + + L K ++ ++L+P AF Sbjct: 31 MEPEMEKLSDEELKGKTAEFRARLEKGEVLENLIPEAF 68
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 29.8 bits (67), Expect = 0.027 Identities = 25/118 (21%), Positives = 42/118 (35%), Gaps = 11/118 (9%) Query: 127 AVLAAEFYELALGDPYVISGAHGDGVYYLIEDILEKFPEP-EAEEADARHPVFAVIGRPN 185 + F+ +L Y S + G+ LIE I KF +++ VF + Sbjct: 202 QEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEK 261 Query: 186 VGKSTLVNAILGEERVITFDMAGTTRDSIHIDFEREGKPFTIIDTAGVRRRGKVDEAV 243 + + G RDS+ I E+E T + T+ K+D+A Sbjct: 262 RQRLAYIRLYSGVLH---------LRDSVRIS-EKEKIKITEMYTSINGELCKIDKAY 309
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 37.9 bits (88), Expect = 6e-06 Identities = 14/30 (46%), Positives = 24/30 (80%) Query: 3 TRKQQGFTLTELLIVMVIAAIMAMIALPNM 32 T KQ+GFTL E+++V+VI ++A + +PN+ Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNL 33
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 32.2 bits (73), Expect = 6e-04 Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 3/51 (5%) Query: 10 RLKDSQSGMALIEVLVAMLVLTIGILALLSVQLRTVASVREAETQTIVSQI 60 R D Q G L+E++V ++++ G+LA L V + + +A+ Q VS I Sbjct: 2 RATDKQRGFTLLEIMVVIVII--GVLASLVVP-NLMGNKEKADKQKAVSDI 49
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 30.7 bits (69), Expect = 0.005 Identities = 14/61 (22%), Positives = 27/61 (44%), Gaps = 1/61 (1%) Query: 17 KGFTIIEFLVAGLLSMIVLMAVGSSYFTSRKLNDAANERLAAQQDLRNAATLIVRDARMA 76 +GFT++E ++ LL + V ++ SR + AA + LR ++ + Sbjct: 4 RGFTLLEMMLILLLMGVSAGMVLLAFPASRD-DSAAQTLARFEAQLRFVQQRGLQTGQFF 62 Query: 77 G 77 G Sbjct: 63 G 63
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 46.4 bits (110), Expect = 3e-09 Identities = 18/63 (28%), Positives = 38/63 (60%) Query: 2 MSNKMEQKGFTLIEMMIVVAILGIISVIAIPSYQSYIEKGYQSQLYTEMVGINNISKQFI 61 M +Q+GFTL+E+M+V+ I+G+++ + +P+ EK + + +++V + N + Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK 60 Query: 62 LKN 64 L N Sbjct: 61 LDN 63
>FRAGILYSIN#Fragilysin metallopeptidase (M10C) enterotoxin signature. Length = 405 Score = 30.0 bits (67), Expect = 0.018 Identities = 26/96 (27%), Positives = 39/96 (40%), Gaps = 7/96 (7%) Query: 60 KYPLTAGLPELRQACANWLKRRYDGLTVDADNEILPVLGSREALFSFVQTVLNPVSDGIK 119 K L G L AC+N D LT D + + + ++ + T LN VSD K Sbjct: 13 KLLLMLGTAALLAACSNEA----DSLTTSIDAPVTASIDLQSVSYTDLATQLNDVSDFGK 68 Query: 120 PAIVSPNPF-YQIYEGATLLGGGEIHFANCPAPSFN 154 I+ N F Q++ ++ +I N FN Sbjct: 69 MIILKDNGFNRQVH--VSMDKRTKIQLDNENVRLFN 102
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.8 bits (67), Expect = 0.001 Identities = 10/56 (17%), Positives = 20/56 (35%), Gaps = 2/56 (3%) Query: 32 AENSLTAMRLAVADKQAEIDGLNAQIDAEIRQ--REAEELKDYRWIHGDAEVPELE 85 +N L + K+AE + A+I+ E L D+ + + + Sbjct: 198 WQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHA 253
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 33.3 bits (76), Expect = 0.002 Identities = 10/53 (18%), Positives = 21/53 (39%) Query: 47 EVPSPQAGVLVEIVAQDGETVVADQVLARVDTAATAAAEAPAAAPAEAAPAAA 99 E+ + ++ EI+ ++GE+V VL ++ A + A Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQ 150
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 29.4 bits (66), Expect = 0.025 Identities = 13/49 (26%), Positives = 15/49 (30%), Gaps = 9/49 (18%) Query: 14 SYGLPVQGGILAHNGEEAAAAYDKLGGKFAVVKAQVHAGGRGKAGGVKV 62 V GG+LAH L +VKA A KV Sbjct: 692 QLYYGVSGGVLAHAN--GVTLGQPLNDTVVLVKA-------PGAKDAKV 731
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 34.0 bits (78), Expect = 6e-04 Identities = 23/104 (22%), Positives = 39/104 (37%), Gaps = 22/104 (21%) Query: 39 WVERGRQAVRQTMEGMFELGRALIILKEHTEHGRFMEIVKSQ-FGLGIAETSRLMSATRR 97 QA++Q + I+++ H R +VK+ +G GI + AT Sbjct: 6 QASLDLQALKQNLS----------IVRQAATHARVWSVVKANAYGHGIERIWSAIGATDG 55 Query: 98 FATPQMQKA---------APKLMDLGKSKL--LELLVEEDVTLV 130 FA +++A P LM G LE+ + +T Sbjct: 56 FALLNLEEAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTC 99
>BACINVASINC#Salmonella/Shigella invasin protein C signature. Length = 409 Score = 28.7 bits (63), Expect = 0.035 Identities = 14/40 (35%), Positives = 23/40 (57%) Query: 276 DLNRLANNATIRANVTVEFDLKQNGSRKPKKIILTSLSTD 315 DLN LANN T +AN V+ L++ + K ++ +S+ Sbjct: 86 DLNALANNVTTKANEVVQTQLREQQAEVGKFFDISGMSSS 125
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 29.5 bits (66), Expect = 0.007 Identities = 7/70 (10%), Positives = 23/70 (32%), Gaps = 6/70 (8%) Query: 34 EQSQKADAEQYFFANKYQFADEKQAFYFERAARFRVLQQGLGGDFERFLKGEIP-NQENL 92 K D ++ + + + + FY+ + R+ + D ++ + I + Sbjct: 265 NLMSKEDYKKIQYDSSSKLLEN---FYYAKDKSDRLKSK--SSDLQKIVMNNINRCTKKD 319 Query: 93 AKYRENITQA 102 + + Sbjct: 320 KILNNTLKKC 329
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 27.5 bits (61), Expect = 0.038 Identities = 12/40 (30%), Positives = 21/40 (52%), Gaps = 3/40 (7%) Query: 1 MKTVSTAVVLAAAAVSLTGCATESSRSLEVEK---VASYN 37 MK + T +VL +A+ L CA+ + +K VA+ + Sbjct: 1 MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNS 40
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 77.4 bits (190), Expect = 4e-19 Identities = 49/187 (26%), Positives = 85/187 (45%), Gaps = 8/187 (4%) Query: 7 KTILVTGASQGLGEQVAKAYAAAGATVILVARHQKKLEKVYDAI-VEAGYPEPFAICFDL 65 K +TGA+QG+GE VA+ A+ GA + V + +KLEKV ++ EA + E F D+ Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPA--DV 66 Query: 66 ISAEEKEFEHFAATIAEATQGKLDGIVHCAGYFYALSPLDFQTVAEWVNQYRINTVAPMG 125 + + A I G +D +V+ AG + + EW + +N+ Sbjct: 67 --RDSAAIDEITARIEREM-GPIDILVNVAGVLR-PGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 126 LTRALFPLLKQSPDASVIFVGESHGETPKAYWGGFGASKAALNYLCKVAADEWERFGNLR 185 +R++ + S++ VG + P+ + +SKAA K E + +R Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYN-IR 181 Query: 186 ANVLVPG 192 N++ PG Sbjct: 182 CNIVSPG 188
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 63.3 bits (154), Expect = 7e-13 Identities = 43/142 (30%), Positives = 65/142 (45%), Gaps = 22/142 (15%) Query: 17 VDDGKSTLIGRLLYDSKALLSDQIKTLESGKSKGLKEAIDFSILTDGLEAEREQGITIDV 76 VD GK+TL LLY+S A+ ++ +++ G ++ TD ER++GITI Sbjct: 12 VDAGKTTLTESLLYNSGAI--TELGSVDKGTTR-----------TDNTLLERQRGITIQT 58 Query: 77 AYRYFSTAKRKFIIADTPGHEQYTRNMVTGASTASAAVVLVDASQLDFGAQPLQLLPQTK 136 F K I DTPGH + + S A++L+ A G Q QT+ Sbjct: 59 GITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKD---GVQ-----AQTR 110 Query: 137 RHSAILRQLNCPHIVVAVNKMD 158 LR++ P I +NK+D Sbjct: 111 ILFHALRKMGIPTIFF-INKID 131
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 28.9 bits (64), Expect = 0.028 Identities = 21/93 (22%), Positives = 33/93 (35%), Gaps = 7/93 (7%) Query: 212 PIYYSHRREVVRRRGLLVPVTPLTPKMPSETSEILDVRFRTVGDISCTCPVESTASTPTE 271 P S+ E+ R PV P P PSET+E + + VE TE Sbjct: 1008 PSVPSNNEEIARVDEA--PVPPPAPATPSETTETVAENSKQESKT-----VEKNEQDATE 1060 Query: 272 IIRETAVADISERSATRLDDQASEAAMEKRKKE 304 + +S + + Q +E A + + Sbjct: 1061 TTAQNREVAKEAKSNVKANTQTNEVAQSGSETK 1093
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 178 bits (453), Expect = 1e-50 Identities = 109/439 (24%), Positives = 181/439 (41%), Gaps = 69/439 (15%) Query: 3 QIRNIAIIAHVDHGKTTLVDQLLRQSGTFRANQQVDE--RVMDSNDLEKERGITILAKNT 60 +I NI ++AHVD GKTTL + LL SG VD+ D+ LE++RGITI T Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 61 AIDYEGYHINIVDTPGHADFGGEVERVLGMVDCVVLLVDAQEGPMPQTRFVTKKALALGL 120 + +E +NI+DTPGH DF EV R L ++D +LL+ A++G QTR + +G+ Sbjct: 62 SFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGI 121 Query: 121 KPIVVINKIDKPSARPSWV-------------IDQTFELFDNLGATD----EQLDFPIV- 162 I INKID+ S V I Q EL+ N+ T+ EQ D I Sbjct: 122 PTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEG 181 Query: 163 -------YASGLSGFAKLEETDESN-------------------DMRPLFDTILKYTPAP 196 Y SG S A E +ES + L + I + Sbjct: 182 NDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSS 241 Query: 197 SGSADETLQLQISQLDYDNYTGRLGIGRILNGRIKPGQTVAVMNHDQQIAQGRINQLLGF 256 + L ++ +++Y RL R+ +G + +V + ++ +I ++ Sbjct: 242 THRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKI----KITEMYTS 297 Query: 257 KGLERVPLEEAEAGDIVIISGIEDIGIGVTITDKDNPKGLPMLSVDEPTLTMDFMVNTSP 316 E +++A +G+IVI+ E + + + D + P L + Sbjct: 298 INGELCKIDKAYSGEIVILQN-EFLKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKP- 355 Query: 317 LAGTEGKFVTSRQIRDRLQKELLT----NVALRVEDTADADVFRVSGRGELHLTILLENM 372 Q R+ L LL + LR + +S G++ + + + Sbjct: 356 ------------QQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALL 403 Query: 373 RRE-GYELAVGKPRVVYRD 390 + + E+ + +P V+Y + Sbjct: 404 QEKYHVEIEIKEPTVIYME 422 Score = 39.1 bits (91), Expect = 5e-05 Identities = 13/85 (15%), Positives = 28/85 (32%), Gaps = 1/85 (1%) Query: 397 EPYENLTVDVPDDNQGAVMEELGRRRGELTNMESDGNGRTRLEYHIPARGLIGFQGEFMT 456 EPY + + P + + + + + + N L IPAR + ++ + Sbjct: 537 EPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKNN-EVILSGEIPARCIQEYRSDLTF 595 Query: 457 LTRGVGLMSHVFDDYAPVKPDMPGR 481 T G + Y + + Sbjct: 596 FTNGRSVCLTELKGYHVTTGEPVCQ 620
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 32.5 bits (74), Expect = 0.004 Identities = 14/75 (18%), Positives = 25/75 (33%), Gaps = 5/75 (6%) Query: 219 RVGAAVGTGGDTEERVKALVEAGVDVIVVDTAHGHSQGVIDRVRWVKETYPHIQVI---- 274 R G V + + + D++V D D + +K+ P + V+ Sbjct: 25 RAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA-FDLLPRIKKARPDLPVLVMSA 83 Query: 275 GGNIATAKAALDLVA 289 TA A + A Sbjct: 84 QNTFMTAIKASEKGA 98
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 26.4 bits (58), Expect = 0.038 Identities = 22/103 (21%), Positives = 41/103 (39%), Gaps = 15/103 (14%) Query: 37 FEELGEHFFKQSIVEMKAADDLIERILFLEGLPN--LQELGKL-----LIGESTEEIIAC 89 FEEL +H + D + ER+L + G P ++E + E++ + Sbjct: 50 FEELYDHAAETV-------DTIAERLLAIGGQPVATVKEYTEHASITDGGNETSASEMVQ 102 Query: 90 DLTKEQEKHEALLA-AIATAEAQQDYVSRDLLEKQKDTNEEHI 131 L + ++ + I AE QD + DL + E+ + Sbjct: 103 ALVNDYKQISSESKFVIGLAEENQDNATADLFVGLIEEVEKQV 145
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 47.2 bits (112), Expect = 2e-09 Identities = 23/105 (21%), Positives = 40/105 (38%), Gaps = 11/105 (10%) Query: 39 KLFERLNHEMEEETTHAEDFIRRILMLGGTP--------KMAR-AELNIGTDVVSCLKAD 89 L E+ + + R+L +GG P + A + T ++A Sbjct: 45 TLHEKFEELYDHAAETVDTIAERLLAIGGQPVATVKEYTEHASITDGGNETSASEMVQAL 104 Query: 90 LQTEYEVRDALKKGIKLCEEAQDYVTRDLMVAQLKDTEEDHAHWL 134 + ++ K I L EE QD T DL V +++ E+ W+ Sbjct: 105 VNDYKQISSESKFVIGLAEENQDNATADLFVGLIEEVEK--QVWM 147
>RTXTOXINC#Gram-negative bacterial RTX toxin-activating protein C signature. Length = 170 Score = 100 bits (251), Expect = 7e-30 Identities = 47/128 (36%), Positives = 71/128 (55%), Gaps = 6/128 (4%) Query: 20 NETEAFGALVWLWAVSPIYQHAGVQEAAVNILPVLKNGQFALFSSNGHPVAYCTWAYFDE 79 E G + WLWA SP++++ V A+N+LP ++ Q+ L + + +PVAYC+WA Sbjct: 5 KPLEILGHVSWLWASSPLHRNWPVSLFAINVLPAIQANQYVLLTRDDYPVAYCSWANLSL 64 Query: 80 ETEWQYLQSNDVLRHSENWCSGNRMWLINWFAPFGDSRMMKRILVHLFPK---REIRWLY 136 E E +YL L +E+W SG+R W I+W APFGD+ + + + FP R IR Sbjct: 65 ENEIKYLNDVTSLV-AEDWTSGDRKWFIDWIAPFGDNGALYKYMRKKFPDELFRAIR--V 121 Query: 137 HRGSEKGK 144 + GK Sbjct: 122 DPKTHVGK 129
>PF06580#Sensor histidine kinase Length = 349 Score = 36.0 bits (83), Expect = 4e-04 Identities = 16/104 (15%), Positives = 41/104 (39%), Gaps = 12/104 (11%) Query: 487 LPPQEAQLQMI-FILQESLSNIRKHARAT-----HVKFTLSEHGGRFTMTIQDNGQGFDT 540 + P +Q+ ++Q + N KH A + ++ G T+ +++ G Sbjct: 246 INPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSL--- 302 Query: 541 EKIGEPTGSHVGLHIMQERAKRIH---AVLEIRSQAQQGTTVSL 581 + GL ++ER + ++ A +++ + + + L Sbjct: 303 ALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVL 346
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 72.6 bits (178), Expect = 4e-17 Identities = 28/117 (23%), Positives = 52/117 (44%), Gaps = 2/117 (1%) Query: 3 IKIILIDDHTLFRSGIKALLSRQHGFEVIGEAADGLSGIKMISRLQPDVVLLDLDMPGMN 62 I++ DD R+ + LSR G++V ++ + + I+ D+V+ D+ MP N Sbjct: 4 ATILVADDDAAIRTVLNQALSRA-GYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 63 GREALSQIISINPQQAVIMLTVSEDSDDLTECMRIGARGYLLKNINADFLLESIRKA 119 + L +I P V++++ + GA YL K + L+ I +A Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 27.8 bits (62), Expect = 0.005 Identities = 17/68 (25%), Positives = 29/68 (42%), Gaps = 11/68 (16%) Query: 21 FGKGSIGRNSSLREQIA-------VQEEKNQTLALRNHSLA-AEVYDLENGQEAISEIAR 72 GKG+ +L E + + E+ T A + L+ A+ YD+ Q I Sbjct: 196 AGKGNASLPGALVEMVLGGATSLKLHEDWGTTPAAIDCCLSVADEYDV---QVMIHTDTL 252 Query: 73 VELGYIQD 80 E G+++D Sbjct: 253 NESGFVED 260
>PF07328#T-DNA border endonuclease VirD1 Length = 144 Score = 31.9 bits (72), Expect = 0.001 Identities = 16/77 (20%), Positives = 27/77 (35%), Gaps = 9/77 (11%) Query: 207 ESQPKLKQILEDDVDNSFTLSDNLWLYLQNYAKKH-------KAKGNGFGFGLVDLDGIS 259 E+ K ++L D ++ N+ + + H A+ G L L + Sbjct: 62 ENDAKTVELLRDMSRAIAGVATNINQIAKAANRTHDPAYHSFMAERKVLGLELSKLSAVL 121 Query: 260 RTL--SARYYKDGSEIL 274 L +R DG E L Sbjct: 122 APLMEVSRRRSDGLERL 138
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 107 bits (269), Expect = 3e-34 Identities = 34/94 (36%), Positives = 57/94 (60%), Gaps = 6/94 (6%) Query: 2 TKSELMVRLAEVFAAKNGTHLLAKDVEYSVKVLVDTMTRSLARGQRIEIRGFGSFDLNHR 61 K +L+ ++AE T L KD +V + ++ LA+G+++++ GFG+F++ R Sbjct: 3 NKQDLIAKVAE------ATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRER 56 Query: 62 PARIGRNPKTGERVEVPEKHVPHFKPGKELRERV 95 AR GRNP+TGE +++ VP FK GK L++ V Sbjct: 57 AARKGRNPQTGEEIKIKASKVPAFKAGKALKDAV 90
>NEISSPPORIN#Neisseria sp. porin signature. Length = 348 Score = 450 bits (1159), Expect = e-161 Identities = 167/398 (41%), Positives = 223/398 (56%), Gaps = 56/398 (14%) Query: 1 MRKKLTALVLSALPLAAVADVSLYGEIKAGVEGRNYQLQLTEAQAANGGASGQVKVTKVT 60 M+K L AL L+ALP+AA+ADV+LYG IKAGV+ + +G KV+KV Sbjct: 1 MKKSLIALTLAALPVAAMADVTLYGAIKAGVQTYR------SVEHTDG------KVSKVE 48 Query: 61 KAKSRIRTKISDFGSFIGFKGSEDLGDGLKAVWQLEQDVSVAGGGATQWGNRESFIGLAG 120 ++I+DFGS IGFKG EDLG+GLKAVWQLEQ SVAG T WGN++SF+GL G Sbjct: 49 TG-----SEIADFGSKIGFKGQEDLGNGLKAVWQLEQGASVAGTN-TGWGNKQSFVGLKG 102 Query: 121 EFGTLRAGRVANQFDDASQAIDPWDSNNDVASQLGI--FKRHDDMPVSVRYDSPEFSGFS 178 FGT+RAG + + + ++ W+S + L I + + +SVRYDSPEF+GFS Sbjct: 103 GFGTIRAGSLNSPLKNTGANVNAWESGKFTGNVLEISGMAQREHRYLSVRYDSPEFAGFS 162 Query: 179 GSVQFVPIQNSKSAYTPAYYTKNTNNNLTLVPAVVGKPGSDVYYAGLNYKNGGFAGNYAF 238 GSVQ+ P NS S + Y+ GLNY+N GF YA Sbjct: 163 GSVQYAPKDNSGS-------------------------NGESYHVGLNYQNSGFFAQYAG 197 Query: 239 KYARHANVGRNAFELFLIGSGSDQAKGTDPLKNHQVHRLTGGYEEGGLNLALAAQLDLSE 298 + R+ G E + + ++ QVHRL GGY+ L +++AAQ ++ Sbjct: 198 LFQRYGE-GTKKIEYD----DQTYSIPSLFVEKLQVHRLVGGYDNNALYVSVAAQQQDAK 252 Query: 299 ----NGDKTKNSTTEIAATASYRFGNAVPRISYAHGFDFIERGKKGENTSYDQIIAGVDY 354 + NS TE+AATA+YRFGN PR+SYAHGF +NT YDQ++ G +Y Sbjct: 253 LYGAMSGNSHNSQTEVAATAAYRFGNVTPRVSYAHGFKGTVDSANHDNT-YDQVVVGAEY 311 Query: 355 DFSKRTSAIVSGAWLKRNTGIGNYTQINAASVGLRHKF 392 DFSKRTSA+VS WL+ G A++V LRHKF Sbjct: 312 DFSKRTSALVSAGWLQGGKGADKIVS-TASAVVLRHKF 348
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 119 bits (300), Expect = 2e-31 Identities = 83/401 (20%), Positives = 163/401 (40%), Gaps = 14/401 (3%) Query: 19 LAIAIFMQMLDATILNTALPEIAADLNESPLDMQLAVISYTLTVALLIPLSGYLADRFGT 78 L I F +L+ +LN +LP+IA D N+ P ++ LT ++ + G L+D+ G Sbjct: 19 LCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGI 78 Query: 79 KKVFFGSIAVFMLGSALCAASGSLFELT-LSRVVQGIGGSMLVPIPRLTILRVYDKSKLL 137 K++ I + GS + S F L ++R +QG G + + + + R K Sbjct: 79 KRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRG 138 Query: 138 NAINYAVMPALIGPVLGPLAGGYLVEYASWHWIFLLNLP-IGLLGFILGRNIMPDIKGSN 196 A +G +GP GG + Y HW +LL +P I ++ ++ Sbjct: 139 KAFGLIGSIVAMGEGVGPAIGGMIAHY--IHWSYLLLIPMITIITVPFLMKLLKKEVRIK 196 Query: 197 ISLDFKGYLIFSAAACLLLLSAESLSHALPPYFALLPLCGGLLFARRYFRHMKTASKPIY 256 D KG ++ S +L S S + F ++ + L+F +H++ + P Sbjct: 197 GHFDIKGIILMSVGIVFFMLFTTSYSIS----FLIVSVLSFLIFV----KHIRKVTDPFV 248 Query: 257 SADLFLIRTFRLGLAGNLFSRLGISSIPFLMPLMFQIAFGFGASLSGWLVA-PVALSSLL 315 L F +G+ ++ ++P M + + G ++ P +S ++ Sbjct: 249 DPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVII 308 Query: 316 VKPLIAPLMKRFGYRTVLLWNTKLLAAFIMLLALPDGNSPLWIWVFLSLAIGACNSLQFS 375 + L+ R G VL L+ + + + ++ + + +G + + Sbjct: 309 FGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTV 368 Query: 376 AMNTLTLADLRPQQTGSGNSLMAVNQQLAISMGIVAGALIL 416 +T+ + L+ Q+ G+G SL+ L+ GI +L Sbjct: 369 I-STIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLL 408
>PF07201#Hypersensitivity response secretion protein HrpJ Length = 293 Score = 33.7 bits (77), Expect = 0.001 Identities = 31/182 (17%), Positives = 59/182 (32%), Gaps = 29/182 (15%) Query: 65 QRSLSKLPALLEQLEENLTKLGVKVHWAETPTEACQIIHDIITAKNGKLMVKGKSMVSEE 124 +R LS A + +EE + + KV E +++ L +S+ Sbjct: 70 KRKLSDSQARVSDVEEQVNQYLSKVPELEQKQNVSELLS--------LLSNSPNISLSQ- 120 Query: 125 IELNHYLEAKGIKAVESDLG-EFIVQMAGEKPTHIVMPAIHKTKEQVSELFHQNLGTPLT 183 L YLE K + E + +P + + EQ + G + Sbjct: 121 --LKAYLEGKSEEPSEQFKMLCGLRDALKGRPE---LAHLSHLVEQALVSMAEEQGETIV 175 Query: 184 DDVDQL---TGFAR------KALRDIYSTADVGLSGVNFAVAETGTLCLVENEGNGRLST 234 ++ + LRD Y A +G G+ ++ L + NG + + Sbjct: 176 LGARITPEAYRESQSGVNPLQPLRDTYRDAVMGYQGIYAIWSD-----LQKRFPNGDIDS 230 Query: 235 TV 236 + Sbjct: 231 VI 232
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 905 bits (2340), Expect = 0.0 Identities = 405/474 (85%), Positives = 422/474 (89%), Gaps = 3/474 (0%) Query: 75 YLTSEAQDLKVRHVSTGASSTGKVSSVVSSSVSRAGVLAGVGKLARLGAKLSTRAVPYVG 134 Y ++ +L V STGA S KV ++SVSRAGVLAGVGKLARLGAK STRAVPYVG Sbjct: 31 YKFDKSLNLNVLESSTGARSLEKVPVKFTASVSRAGVLAGVGKLARLGAKFSTRAVPYVG 90 Query: 135 TALLAHDVYETFKEDIQAQGYQYDPETDKFVKGYEYSNCLWYEDKRRINRTYGCYGVDSS 194 TALLAHDVYETFKEDIQA+GYQYDPETDKFVKGYEYSNCLWYED+RRINRTYGCYGVDSS Sbjct: 91 TALLAHDVYETFKEDIQARGYQYDPETDKFVKGYEYSNCLWYEDERRINRTYGCYGVDSS 150 Query: 195 IMRLMSDDSRFPEVKELMESQMYRLARPFWNWHKEELNKLSSLDWNNFVLNSCTFDWNGG 254 IMRLMSD SRFPEVKELMESQM RLARP+W ++ N+ + N+ C F NGG Sbjct: 151 IMRLMSDYSRFPEVKELMESQMERLARPYW---EKLRNRPDMYYFKNYNFKRCYFGLNGG 207 Query: 255 DCVVNKGDDFRNGADFSLIRNSKYKEEMDAKKLEEILSLKVDANPDKYIKATGYPGYSEK 314 DC+V KGDD R FSL NSKYKEEMDAKKLEEILSLKVDANPDKYIKATGYPGYSEK Sbjct: 208 DCLVAKGDDGRTFISFSLQGNSKYKEEMDAKKLEEILSLKVDANPDKYIKATGYPGYSEK 267 Query: 315 VEVAPGTKVNMGPVTDRNGNPVQVVATFGRDSQGNTTVDVQVIPRPDLTPGSAEAPNAQP 374 VEVAPGTKVNMGPVTDRNGNPVQVVATFGRDSQGNTTVDVQVIPRPDLTPGSAEAPNAQP Sbjct: 268 VEVAPGTKVNMGPVTDRNGNPVQVVATFGRDSQGNTTVDVQVIPRPDLTPGSAEAPNAQP 327 Query: 375 LPEVSPAENPANNPNPNENPGTSPNPEPDPDLNPDANPDTDGQPGTRPDSPAVPGRTNGR 434 LPEVSPAENPANNP PNENPGT PNPEPDPDLNPDANPDTDGQPGTRPDSPAVP R NGR Sbjct: 328 LPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTDGQPGTRPDSPAVPDRPNGR 387 Query: 435 DGKDGKDGKDGGLLCKFFPDILACDRLPESNPAEDLNLPSETVNVEFQKSGIFQDSAQCP 494 K+ K+G+DGGLLCKFFPDILACDRLPE NPAEDLNLPSETVNVEFQKSGIFQDSAQCP Sbjct: 388 HRKERKEGEDGGLLCKFFPDILACDRLPEPNPAEDLNLPSETVNVEFQKSGIFQDSAQCP 447 Query: 495 APVTFTVTVLDSSRQFAFSFENACTIAERLRYMLLALAWAVAAFFCIRTVSREV 548 APVTFTVTVLDSSRQFAFSFENACTIAERLRYMLLALAWAVAAFFCIRTVSREV Sbjct: 448 APVTFTVTVLDSSRQFAFSFENACTIAERLRYMLLALAWAVAAFFCIRTVSREV 501
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 27.9 bits (62), Expect = 0.044 Identities = 10/55 (18%), Positives = 21/55 (38%), Gaps = 3/55 (5%) Query: 190 AAEIYPMVLNYLGKNPNSSNTEDIREATALLK---KNRPNIKRFTSSGFIDDLAR 241 ++ V + +NPN ++E + + PN + + G + AR Sbjct: 23 GCRLFDQVYVAVLRNPNKQPMFSVQERLEQIAKAIAHLPNAQVDSFEGLTVNYAR 77
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 31.6 bits (71), Expect = 0.017 Identities = 26/93 (27%), Positives = 36/93 (38%), Gaps = 1/93 (1%) Query: 694 EAITGLNALKWAQEQERLVKDIIAETKAQTEKDVLAKIQAGAAHAKALEKELARAKAELA 753 I L A K A E + + E AKI+ A ALE E A + + Sbjct: 246 AKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQ 305 Query: 754 VHAGAKLLDDAKDLGAAKLVAAQIEADAAALRE 786 V A +DL A++ Q+EA+ L E Sbjct: 306 V-LNANRQSLRRDLDASREAKKQLEAEHQKLEE 337
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 29.3 bits (65), Expect = 0.029 Identities = 15/75 (20%), Positives = 26/75 (34%), Gaps = 3/75 (4%) Query: 75 NPR--QTHQFAQSQSLTKTDAKDAKMPAFFAQMKAQKEDWQTMPYHPPTEAEEVLEALVN 132 NP + +Q + ++T + A +P+ + P PP A Sbjct: 982 NPEVEKRNQTVDTTNITTPNNIQADVPSV-PSNNEEIARVDEAPVPPPAPATPSETTETV 1040 Query: 133 RRNQSADMRTAEKNR 147 N + +T EKN Sbjct: 1041 AENSKQESKTVEKNE 1055
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 131 bits (332), Expect = 4e-39 Identities = 37/151 (24%), Positives = 64/151 (42%), Gaps = 6/151 (3%) Query: 8 VLVVDDETDILDLMEMTLMKMGLRVHTASGVAEAKNKLDSQRYSLVLTDMRMPDGSGLEV 67 +LV DD+ I ++ L + G V S A + + LV+TD+ MPD + ++ Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 68 VQHINSRLLDTPVAVITAFGNADQAQEALRCGAFD--PDTMQIQDYLDQIERDIIEQT-- 123 + I D PV V++A A +A GA+D P + + + I R + E Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRR 125 Query: 124 LKQTEGNRTQAAKRLGIS--FRSMRYRMERL 152 + E + +G S + + + RL Sbjct: 126 PSKLEDDSQDGMPLVGRSAAMQEIYRVLARL 156 Score = 62.2 bits (151), Expect = 4e-14 Identities = 15/56 (26%), Positives = 28/56 (50%) Query: 99 GAFDPDTMQIQDYLDQIERDIIEQTLKQTEGNRTQAAKRLGISFRSMRYRMERLNI 154 G P + L ++E +I L T GN+ +AA LG++ ++R ++ L + Sbjct: 420 GDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGV 475
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 29.9 bits (67), Expect = 0.022 Identities = 18/105 (17%), Positives = 31/105 (29%), Gaps = 28/105 (26%) Query: 15 VAQNLAAIPNNDVTVIDIDEKALQETGS--RLDVQT----------------VFGNGASP 56 + ++++DI+ L E G R+ ++T + NGA Sbjct: 277 KPSARIEV---ALSIVDINADQLTELGVDWRVGIRTGNNHQVVIKTTGDQSNIASNGALG 333 Query: 57 FTLERAGAEDADLLL----ALSRSDETNIVACKVAADLFNIPGRI 97 + A D LL L +V+ N I Sbjct: 334 SLV---DARGLDYLLARVNLLENEGSAQVVSRPTLLTQENAQAVI 375
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 29.4 bits (66), Expect = 0.026 Identities = 15/58 (25%), Positives = 23/58 (39%), Gaps = 13/58 (22%) Query: 194 GKPAP--GAFTMDAFIKGATQNRLTVDVPYIQRADVETEGILWGGNLSV--LASLAGT 247 G G +MD VD+ +A + T LWG + + +A+ AGT Sbjct: 290 GVRTMTVGTVSMDMLA---------VDLTPCPQAGIGTPVELWGKEIKIDDVAAAAGT 338
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 887 bits (2294), Expect = 0.0 Identities = 410/464 (88%), Positives = 423/464 (91%), Gaps = 3/464 (0%) Query: 54 IEHVPTGARSLEKVPVKFTASVSRAAVLSGVGKLARLGAKLSTRAVPYVGTALLAHDVYE 113 + TGARSLEKVPVKFTASVSRA VL+GVGKLARLGAK STRAVPYVGTALLAHDVYE Sbjct: 41 VLESSTGARSLEKVPVKFTASVSRAGVLAGVGKLARLGAKFSTRAVPYVGTALLAHDVYE 100 Query: 114 TFKEDIQAQGYQYDPETDKFVKGYEYSNCLWYEDKRRINRTYGCYGVDSSIMRLMSDDSR 173 TFKEDIQA+GYQYDPETDKFVKGYEYSNCLWYED+RRINRTYGCYGVDSSIMRLMSD SR Sbjct: 101 TFKEDIQARGYQYDPETDKFVKGYEYSNCLWYEDERRINRTYGCYGVDSSIMRLMSDYSR 160 Query: 174 FPEVKELMESQMYRLARPFWNWHKEELNKLSSLDWNNFVLNRCTFNWNGGDCLVNKGDDF 233 FPEVKELMESQM RLARP+W ++ N+ + N+ RC F NGGDCLV KGDD Sbjct: 161 FPEVKELMESQMERLARPYW---EKLRNRPDMYYFKNYNFKRCYFGLNGGDCLVAKGDDG 217 Query: 234 RNGADFSLIRNSKYKEEMDAKKLEEILSLKVDANPDKYIKATGYPGYSEKVEVAPGTKVN 293 R FSL NSKYKEEMDAKKLEEILSLKVDANPDKYIKATGYPGYSEKVEVAPGTKVN Sbjct: 218 RTFISFSLQGNSKYKEEMDAKKLEEILSLKVDANPDKYIKATGYPGYSEKVEVAPGTKVN 277 Query: 294 MGPVTDRNGNPVQVVATFGRDSQGNTTVDVQVIPRPDLTPGSAEAPNAQPLPEVSPAENP 353 MGPVTDRNGNPVQVVATFGRDSQGNTTVDVQVIPRPDLTPGSAEAPNAQPLPEVSPAENP Sbjct: 278 MGPVTDRNGNPVQVVATFGRDSQGNTTVDVQVIPRPDLTPGSAEAPNAQPLPEVSPAENP 337 Query: 354 ANNPNPNENPGTSPNPEPDPDLNPDANPDTDGQPGTRPDSPAVPGRTNGRDGKDGKDGKD 413 ANNP PNENPGT PNPEPDPDLNPDANPDTDGQPGTRPDSPAVP R NGR K+ K+G+D Sbjct: 338 ANNPAPNENPGTRPNPEPDPDLNPDANPDTDGQPGTRPDSPAVPDRPNGRHRKERKEGED 397 Query: 414 GGLLCKFFPDILACDRLPESNPAEDLNLPSETVNVEFQKSGIFQDSAQCPAPVTFTVTVL 473 GGLLCKFFPDILACDRLPE NPAEDLNLPSETVNVEFQKSGIFQDSAQCPAPVTFTVTVL Sbjct: 398 GGLLCKFFPDILACDRLPEPNPAEDLNLPSETVNVEFQKSGIFQDSAQCPAPVTFTVTVL 457 Query: 474 DSSRQFAFSFENACTIAERLRYMLLALAWAVAAFFCIRTVSREV 517 DSSRQFAFSFENACTIAERLRYMLLALAWAVAAFFCIRTVSREV Sbjct: 458 DSSRQFAFSFENACTIAERLRYMLLALAWAVAAFFCIRTVSREV 501
>OUTRMMBRANEA#Outer membrane protein A signature. Length = 346 Score = 28.4 bits (63), Expect = 0.027 Identities = 15/62 (24%), Positives = 26/62 (41%), Gaps = 5/62 (8%) Query: 174 HESNSISSLGLGVIAGVGFD--ITPKLTLDTGYRY-HNWGRLE--NTRFKTHEVSLGMRY 228 + G+ + G + ITP++ Y++ +N G TR +SLG+ Y Sbjct: 130 NVYGKNHDTGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDAHTIGTRPDNGMLSLGVSY 189 Query: 229 HF 230 F Sbjct: 190 RF 191
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 72.2 bits (177), Expect = 5e-15 Identities = 68/321 (21%), Positives = 113/321 (35%), Gaps = 84/321 (26%) Query: 469 VMGHVDHGKTSLLDYI-----RRTKVVQGEAG-------------GITQHIGAYHVETPR 510 V+ HVD GKT+L + + T++ + G GIT G + Sbjct: 8 VLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWEN 67 Query: 511 GVITFLDTPGHEAFTAMRARGAKATDIVILVVAADDGVMPQTIEAIAHAKAAGVPMVVAV 570 + +DTPGH F A R D IL+++A DGV QT + G+P + + Sbjct: 68 TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFI 127 Query: 571 NKIDKEAANPER----IRQELTAHEVV-------PDEWGGDVQFIDV------------- 606 NKID+ + I+++L+A V+ P+ + + Sbjct: 128 NKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGNDDLLE 187 Query: 607 --------------------------------SAKKGLNIDALLEAVLLEAEVLELTAPV 634 SAK + ID L+E + + T Sbjct: 188 KYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVIT--NKFYSSTHRG 245 Query: 635 DAPAKGIIVEARLDKGRGAVATLLVQSGTLKKGD-MLLAGTAFGKIRAM-VDENGK--SI 690 + G + + + R +A + + SG L D + ++ KI M NG+ I Sbjct: 246 QSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKIKITEMYTSINGELCKI 305 Query: 691 TEAGPS----IPVEILGLSDV 707 +A + E L L+ V Sbjct: 306 DKAYSGEIVILQNEFLKLNSV 326
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 32.1 bits (73), Expect = 0.004 Identities = 17/53 (32%), Positives = 20/53 (37%), Gaps = 11/53 (20%) Query: 302 GIRTGTGAATGALIG-----------LGLDIATLGGSLGLGTAIGGFLGGILP 343 GI TGA GA I G A G + G +GG +GG P Sbjct: 107 GITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSP 159
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 353 bits (907), Expect = e-123 Identities = 144/357 (40%), Positives = 203/357 (56%), Gaps = 10/357 (2%) Query: 2 RPLNVQIRLGNLRHNYRILKEMHGG-KLLAVVKADAYGHGAVRCAFALADLADGFAVATI 60 RP+ + L L+ N I+++ ++ +VVKA+AYGHG R A+ DGFA+ + Sbjct: 3 RPIQASLDLQALKQNLSIVRQAATHARVWSVVKANAYGHGIERIWSAIGA-TDGFALLNL 61 Query: 61 DEGIRLRESGITHPIVLLEGVFEASEYEAVEQYSLWPAVGNQWQLEALLIRHWKKTVKVW 120 +E I LRE G PI++LEG F A + E +Q+ L V + WQL+AL K + ++ Sbjct: 62 EEAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQNARLKAPLDIY 121 Query: 121 LKMDSGMHRTGFFPHDYASAYAALKQSEYVDSIVKFSHFSCADEPESGMTEIQMEAFDLG 180 LK++SGM+R GF P + + L+ V + SHF+ A+ P+ M + Sbjct: 122 LKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHFAEAEHPDGISG--AMARIEQA 179 Query: 181 TEGLEGEESLANSAAILNVPEARRDWGRAGLALYGISPFGG----GDDRLKPVMRLSTRI 236 EGLE SL+NSAA L PEA DW R G+ LYG SP G + L+PVM LS+ I Sbjct: 180 AEGLECRRSLSNSAATLWHPEAHFDWVRPGIILYGASPSGQWRDIANTGLRPVMTLSSEI 239 Query: 237 FGERVLQPHSPIGYGATFYTSKSTRVGLIACGYADGYPRRAPSNSPVAVDGKLTRVIGRV 296 G + L+ +GYG + R+G++A GYADGYPR AP+ +PV VDG T +G V Sbjct: 240 IGVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAPTGTPVLVDGVRTMTVGTV 299 Query: 297 SMDMMTIELDA-SQEGLGHEVELWGDTVNINTVAEAAGTIPYELMCNI-KRAKFTYI 351 SMDM+ ++L Q G+G VELWG + I+ VA AAGT+ YELMC + R + Sbjct: 300 SMDMLAVDLTPCPQAGIGTPVELWGKEIKIDDVAAAAGTVGYELMCALALRVPVVTV 356
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 30.9 bits (70), Expect = 0.011 Identities = 12/48 (25%), Positives = 19/48 (39%), Gaps = 2/48 (4%) Query: 279 TVGKDGINPDEPMTLETVDRFAREIGFKGRYQLNLPKGEDGVWTLSQD 326 +V +G T + +IGFKG+ L G +W + Q Sbjct: 36 SVAHNGAQAASVETGTGIVDLGSKIGFKGQEDLG--NGLKAIWQVEQK 81
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 38.0 bits (88), Expect = 3e-05 Identities = 16/55 (29%), Positives = 18/55 (32%) Query: 311 APVKKAEPAPTPAPAAEPAASAPAEAAQAVSEAKPAAAEPKAEEKAAPAAKADGK 365 A EP P P EP P EA + + KP K K D K Sbjct: 65 AVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVK 119 Score = 33.0 bits (75), Expect = 0.001 Identities = 11/51 (21%), Positives = 17/51 (33%) Query: 310 KAPVKKAEPAPTPAPAAEPAASAPAEAAQAVSEAKPAAAEPKAEEKAAPAA 360 +APV +P P P P +P A+ + A P + Sbjct: 89 EAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTS 139 Score = 29.2 bits (65), Expect = 0.020 Identities = 9/48 (18%), Positives = 16/48 (33%) Query: 313 VKKAEPAPTPAPAAEPAASAPAEAAQAVSEAKPAAAEPKAEEKAAPAA 360 ++K +P P P P P + V + E A + + Sbjct: 94 IEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSST 141
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 30.5 bits (68), Expect = 0.023 Identities = 28/155 (18%), Positives = 54/155 (34%), Gaps = 18/155 (11%) Query: 205 ELAVFSSPAPFQKYLFLLHVGDHIYGGLEHTDSTALLADRHSLPPYGMTDADDTYTTLLG 264 + +++SP ++ + G + + + + Y T + YT L Sbjct: 448 TVVIYNSPEEYKLNRIIN--------GFSTDNGGIYIENIGTFFTYERTPEESIYT-LEE 498 Query: 265 LFSHEYFHAWNVKSIKPAAFVPYDLDKENYTEQLWAFEGITSYYDDLFLARSRTISPESY 324 LF HE+ H + + P + + +E W EG ++ A S Sbjct: 499 LFRHEFTHYLQGRYVVPGMWGQGEFYQEGVL--TWYEEGTAEFF-----AGSTRTDGIKP 551 Query: 325 LNLLAQGITRVQQTRGRLRQTLAESSFTAWNKFYK 359 + QG+ + R L L + + +W FY Sbjct: 552 RKSVTQGLAYDRNNRMSLYGVL-HAKYGSW-DFYN 584
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 92.0 bits (228), Expect = 2e-24 Identities = 50/208 (24%), Positives = 80/208 (38%), Gaps = 17/208 (8%) Query: 78 EPPKPVLKPVVTKKADADIQQPKEEPKPEEKPKPEEKPKPEPKPEAKPVPKPAEKPVEKP 137 E P P VT A AD++ P +P PE +PEP+PE P P P E PV Sbjct: 42 ELPAPAQPISVTMVAPADLEPP-----QAVQPPPEPVVEPEPEPEPIPEP-PKEAPVVIE 95 Query: 138 SEKPAEHPGNASAKADSEQGNGEDKGTGTKGDGTGRGEGSGKGSGGVKGEHGEGAGSSKG 197 KP P K EQ + K + + A +SK Sbjct: 96 KPKPKPKPKPKPVK-KVEQPKRD-----VKPVESRPASPFENTAPARPTSSTATAATSKP 149 Query: 198 NPLRANGSIP----RPAYPTLSMENDEQGTVVLSVLVSPGGHVESVKIVKSSGFSRLDNA 253 A+G +P YP + +G V + V+P G V++V+I+ + + + Sbjct: 150 VTSVASGPRALSRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFERE 209 Query: 254 ARKAAQNGHFQ-ANAWTEFKVPVKFELN 280 + A + ++ + V + F++N Sbjct: 210 VKNAMRRWRYEPGKPGSGIVVNILFKIN 237
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 511 bits (1318), Expect = 0.0 Identities = 185/475 (38%), Positives = 294/475 (61%), Gaps = 1/475 (0%) Query: 2 FFSALKSFLSRYITVWRNVWAVRDQLKPPKRTAEEQAFLPAHLELTDTPVSAAPKWAARF 61 + FL RY VW W +R QL P R +E FLPAHLEL +TPVS P+ A F Sbjct: 4 WLMGFSEFLLRYKLVWSETWKIRKQLDTPVREKDENEFLPAHLELIETPVSRRPRLVAYF 63 Query: 62 IMAFALLALLWSWFGKIDIVAAASGKTVSGGRSKTIQPLETAVVKAVHVRDGQHVKQGET 121 IM F ++A + S G+++IVA A+GK GRSK I+P+E ++VK + V++G+ V++G+ Sbjct: 64 IMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDV 123 Query: 122 LAELEAVGTDSDVVQSEQALQAAQLSKLRYEAVLAALESRTVPHIDM-AQARSLGLSDAD 180 L +L A+G ++D ++++ +L A+L + RY+ + ++E +P + + + +S+ + Sbjct: 124 LLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEE 183 Query: 181 VQSAQVLAQHQYQAWAAQDAQLQSALRGHQAELQSAKAQEQKLVSVGAIEQQKTADYRRL 240 V L + Q+ W Q Q + L +AE + A+ + ++ +E+ + D+ L Sbjct: 184 VLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSL 243 Query: 241 RADNFISEHAFLEQQSKSVSNWNDLESTRGQMRQIQAAIAQAEQNRVLNTQNLKRDTLDA 300 I++HA LEQ++K V N+L + Q+ QI++ I A++ L TQ K + LD Sbjct: 244 LHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDK 303 Query: 301 LRQANEQIDQYRGQTDKAKQRQQLMTIQSPADGTVQELATYTVGGVVQAAQKMMVIAPDD 360 LRQ + I + K ++RQQ I++P VQ+L +T GGVV A+ +MVI P+D Sbjct: 304 LRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPED 363 Query: 361 DKMDVEVLVLNKDIGFVEQGQDAVVKIESFPYTRYGYLTGKVKSVSHDAVSHEQLGLVYT 420 D ++V LV NKDIGF+ GQ+A++K+E+FPYTRYGYL GKVK+++ DA+ ++LGLV+ Sbjct: 364 DTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFN 423 Query: 421 AVVSLDKHTLNIDGKAVNLTAGMNVTAEIKTGKRRVLDYLLSPLQTKLDESFRER 475 ++S++++ L+ K + L++GM VTAEIKTG R V+ YLLSPL+ + ES RER Sbjct: 424 VIISIEENCLSTGNKNIPLSSGMAVTAEIKTGMRSVISYLLSPLEESVTESLRER 478
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 797 bits (2060), Expect = 0.0 Identities = 390/499 (78%), Positives = 421/499 (84%), Gaps = 10/499 (2%) Query: 1 MYALSEKYNDNGFKAYKVLGEGGGIHTEYNYKFDKSLNLNVLESSTGARSLEKVPVKVTA 60 MYALSEKYNDNGFKAYKVLGEGGGI+TEYNYKFDKSLNLNVLESSTGARSLEKVPVK TA Sbjct: 1 MYALSEKYNDNGFKAYKVLGEGGGIYTEYNYKFDKSLNLNVLESSTGARSLEKVPVKFTA 60 Query: 61 SVSRAAVLSGVGKLARLGAKLSTRAVPYVGTALLAHDVYETFKEDIQAQGYQYDPETDKF 120 SVSRA VL+GVGKLARLGAK STRAVPYVGTALLAHDVYETFKEDIQA+GYQYDPETDKF Sbjct: 61 SVSRAGVLAGVGKLARLGAKFSTRAVPYVGTALLAHDVYETFKEDIQARGYQYDPETDKF 120 Query: 121 VKGYEYSNCLWYEDKRRINRTYGCYGVDSSIMRLMSDDSRFPEVKELMESQMYRLARPFW 180 VKGYEYSNCLWYED+RRINRTYGCYGVDSSIMRLMSD SRFPEVKELMESQM RLARP+W Sbjct: 121 VKGYEYSNCLWYEDERRINRTYGCYGVDSSIMRLMSDYSRFPEVKELMESQMERLARPYW 180 Query: 181 NWHKEELNKLSSLDWNNFVLNRCTFNWNGGDCLVNKGDDFRNGADFSLIRNSKYKEEMDA 240 ++ N+ + N+ RC F NGGDCLV KGDD R FSL NSKYKEEMDA Sbjct: 181 ---EKLRNRPDMYYFKNYNFKRCYFGLNGGDCLVAKGDDGRTFISFSLQGNSKYKEEMDA 237 Query: 241 KKLEEILSLKVDANPDKYIKATGYPGYSEKVEVAPGTKVNMGPVTDRNGNPVQVVATFGR 300 KKLEEILSLKVDANPDKYIKATGYPGYSEKVEVAPGTKVNMGPVTDRNGNPVQVVATFGR Sbjct: 238 KKLEEILSLKVDANPDKYIKATGYPGYSEKVEVAPGTKVNMGPVTDRNGNPVQVVATFGR 297 Query: 301 DSQGNTTVDVQVIPRPDLTPGSAEAPNAQPLPEVSPAENPANNPNPNENPGTSPNPEPDP 360 DSQGNTTVDVQVIPRPDLTPGSAEAPNAQPLPEVSPAENPANNP PNENPGT PNPEPDP Sbjct: 298 DSQGNTTVDVQVIPRPDLTPGSAEAPNAQPLPEVSPAENPANNPAPNENPGTRPNPEPDP 357 Query: 361 DLNPDANPDTDGQPGTRPDSPAVPDRPNGRHRKERKEGEDGGLLCDYFPEILACQEMGKP 420 DLNPDANPDTDGQPGTRPDSPAVPDRPNGRHRKERKEGEDGGLLC +FP+ILAC + +P Sbjct: 358 DLNPDANPDTDGQPGTRPDSPAVPDRPNGRHRKERKEGEDGGLLCKFFPDILACDRLPEP 417 Query: 421 SDGMFHDISIPQVIDDKTWSSHNFLPSNGVCPQPKTFHVF----GRQYQASYEPLCVFAE 476 + D+++P + + + CP P TF V RQ+ S+E C AE Sbjct: 418 NPA--EDLNLPSETVNVEFQKSGIFQDSAQCPAPVTFTVTVLDSSRQFAFSFENACTIAE 475 Query: 477 KIRFAVL-LAFIIMSAFVV 494 ++R+ +L LA+ + + F + Sbjct: 476 RLRYMLLALAWAVAAFFCI 494
>PF04605#Virulence-associated protein D (VapD) Length = 125 Score = 105 bits (264), Expect = 2e-32 Identities = 24/90 (26%), Positives = 41/90 (45%), Gaps = 2/90 (2%) Query: 1 MSRYLITFDMDTNCLKDNYHGNNYTNAYSDIKTILARHGFENIQGSVYLGREGISEAHGT 60 ++R I FD+ T L+ + + YS IK + +GFE+ Q S Y +E I+E Sbjct: 3 INRKAINFDLSTKSLEKYFK--DTREPYSLIKKFMLENGFEHRQYSGYTSKEPINERRVI 60 Query: 61 IAIQELTARFDWFYSCISNIKFYRLESDLN 90 + +LT +F W C+ + + Sbjct: 61 RIVNKLTKKFTWLGECVKEFDITEIGEQYS 90
>RTXTOXINC#Gram-negative bacterial RTX toxin-activating protein C signature. Length = 170 Score = 100 bits (250), Expect = 1e-29 Identities = 40/132 (30%), Positives = 58/132 (43%), Gaps = 3/132 (2%) Query: 21 NESEALGAITWLWYQSPTHRQVPIVEMMTYILPVLKNGQFALFCKGTQPIGYISWAYFDE 80 E LG ++WLW SP HR P+ +LP ++ Q+ L + P+ Y SWA Sbjct: 5 KPLEILGHVSWLWASSPLHRNWPVSLFAINVLPAIQANQYVLLTRDDYPVAYCSWANLSL 64 Query: 81 VAQAHYLESDRHLRDNSDWNCGDNIWLIQWFAPLGHSHQMRSAVRQLFPSTTVRAL-YHK 139 + YL L DW GD W I W AP G + + +R+ FP RA+ Sbjct: 65 ENEIKYLNDVTSLVAE-DWTSGDRKWFIDWIAPFGDNGALYKYMRKKFPDELFRAIRVDP 123 Query: 140 GSDKGLRILTFK 151 + G ++ F Sbjct: 124 KTHVG-KVSEFH 134
>PF05860#haemagglutination activity domain. Length = 117 Score = 81.4 bits (201), Expect = 4e-20 Identities = 19/139 (13%), Positives = 45/139 (32%), Gaps = 24/139 (17%) Query: 83 IIADKAAPKTQQATILQTGNGIPQVNIQTPTSAGVSVNQYAQFDVGNRGAILNNSRSNTQ 142 I D P + + T + T + + + + +F V G N+ +N Q Sbjct: 3 ITPDTTLPIN---SNITTEGNTRIIERGTQAGSNLFHS-FQEFSVPTSGTAFFNNPTNIQ 58 Query: 143 TQLGGWIQGNPWLARGEARVVVNQINSSHSSQMNGYIEVGGRRAEVVIANPAGIAVNGGG 202 +++++ S ++G I A + + NP GI Sbjct: 59 -------------------NIISRVTGGSVSNIDGLIRANAT-ANLFLINPNGIIFGQNA 98 Query: 203 FINASRATLTTGQPQYQAG 221 ++ + + + + + Sbjct: 99 RLDIGGSFVGSTANRLKFA 117
>PF05860#haemagglutination activity domain. Length = 117 Score = 100 bits (250), Expect = 9e-27 Identities = 30/128 (23%), Positives = 55/128 (42%), Gaps = 14/128 (10%) Query: 73 AQITTDKSAPKNQQVVILKTNTGAPLVNIQTPNGRGLSHNRYTQFDVDNKGAVLNNDRNN 132 AQIT D + P N + T ++ T G L H+ + +F V G N+ Sbjct: 1 AQITPDTTLPINSNIT---TEGNTRIIERGTQAGSNLFHS-FQEFSVPTSGTAFFNNP-- 54 Query: 133 NPFVVKGSAQLILNEVRG-TASKLNGIVTVGGQKADVIIANPNGITVNGGGFKNVGRGIL 191 + Q I++ V G + S ++G++ A++ + NPNGI ++G + Sbjct: 55 ------TNIQNIISRVTGGSVSNIDGLIRANAT-ANLFLINPNGIIFGQNARLDIGGSFV 107 Query: 192 TTGAPQIG 199 + A ++ Sbjct: 108 GSTANRLK 115
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 268 bits (687), Expect = 7e-82 Identities = 103/420 (24%), Positives = 188/420 (44%), Gaps = 32/420 (7%) Query: 370 MNIVASDSVNGKMTLSLKDVPWDQALDLVMQARNLDMRQQGNIVNIAPRDELLAKDKALL 429 + IV G ++ + W A D+V L+ + + + ++A ++ Sbjct: 180 LTIVERVDNAGDRSVVTVPLSWASAADVVKLVTELNKDTSKSALPGSMVANVVADERTNA 239 Query: 430 --------QAEKDIADLGALY--------SQNFQLKYKN----VEEFRSILRLDNADTTG 469 ++ IA + L ++ LKY VE I ++ Sbjct: 240 VLVSGEPNSRQRIIAMIKQLDRQQATQGNTKVIYLKYAKASDLVEVLTGISSTMQSEKQA 299 Query: 470 NRNTLISGRG-SVLIDPATNTLIVTDTRSVIEKFRKLIDELDVPAQQVMIEARIVEAADG 528 + + + TN LIVT V+ ++I +LD+ QV++EA I E D Sbjct: 300 AKPVAALDKNIIIKAHGQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDA 359 Query: 529 FSRDLGVKFG--ATGKKKLKNDTSAFGWGVNSGFGGDDKWGAETKINLPITAAANSISLV 586 +LG+++ G + N G +++ G +++ + ++ + +A +S + + Sbjct: 360 DGLNLGIQWANKNAGMTQFTNS----GLPISTAIAGANQYNKDGTVSSSLASALSSFNGI 415 Query: 587 RA-ISSGALNLELSASESLSKTKTLANPRVLTQNRKEAKIESGYEIPF-TVTSIANGGSS 644 A G + L+A S +K LA P ++T + EA G E+P T + +G + Sbjct: 416 AAGFYQGNWAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVPVLTGSQTTSGDNI 475 Query: 645 TNTELKKAV-LGLTVTPNITPDGQIIMTVKINKDSPAQCASGNQTIL--CISTKNLNTQA 701 NT +K V + L V P I +++ ++ S A AS + L +T+ +N Sbjct: 476 FNTVERKTVGIKLKVKPQINEGDSVLLEIEQEVSSVADAASSTSSDLGATFNTRTVNNAV 535 Query: 702 MVENGGTLIVGGIYEEDNGNTLTKVPLLGDIPVIGNLFKTRGKKTDRRELLIFITPRIMG 761 +V +G T++VGG+ ++ +T KVPLLGDIPVIG LF++ KK +R L++FI P ++ Sbjct: 536 LVGSGETVVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRNLMLFIRPTVIR 595 Score = 61.1 bits (148), Expect = 1e-11 Identities = 32/183 (17%), Positives = 74/183 (40%), Gaps = 17/183 (9%) Query: 349 SLDFQDVEIRTILQILAKESGMNIVASDSVNGKMTL-SLKDVPWDQALDL---VMQARNL 404 S F+ +I+ + ++K ++ SV G +T+ S + +Q V+ Sbjct: 31 SASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRSYDMLNEEQYYQFFLSVLDVYGF 90 Query: 405 DMRQQGN-IVNIAPRDELLAKDKALLQAEKDIADLGA-LYSQNFQLKYKNVEEFRSILRL 462 + N ++ + + AK A+ A +G + ++ L + +LR Sbjct: 91 AVINMNNGVLKVVRSKD--AKTAAVPVASDAAPGIGDEVVTRVVPLTNVAARDLAPLLRQ 148 Query: 463 DNADTTGNRNTLISGRGSVLIDPATNTLIVTDTRSVIEKFRKLIDELDVPAQQVMIEARI 522 N + +G GSV+ +N L++T +VI++ +++ +D + ++ + Sbjct: 149 LNDN---------AGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDNAGDRSVVTVPL 199 Query: 523 VEA 525 A Sbjct: 200 SWA 202
>BACTRLTOXIN#Bacterial toxin signature. Length = 266 Score = 30.7 bits (69), Expect = 0.005 Identities = 26/109 (23%), Positives = 44/109 (40%), Gaps = 21/109 (19%) Query: 26 GGITDHHADGFGIGFFEGKGVRLFHDDKPSVNSPVADLVRAYQIKSENVIAH-----IRK 80 GGIT H + F G + VR++ + + +++ V Q ++V A R Sbjct: 140 GGITKHEGNHFDNGNLQNVLVRVYENKRNTISFEV-------QTDKKSVTAQELDIKARN 192 Query: 81 ASQGQTSL--ANTHPFMREMWGGYWLF-AHNGHL--IDFFPEQGEFFHP 124 + +L N+ P+ GY F +NG+ D P G+ F Sbjct: 193 FLINKKNLYEFNSSPYET----GYIKFIENNGNTFWYDMMPAPGDKFDQ 237
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 52.9 bits (127), Expect = 2e-09 Identities = 42/237 (17%), Positives = 88/237 (37%), Gaps = 29/237 (12%) Query: 281 TVMVTGAGGSIGSELCRQIIRRRPEKLLLFELSEFALYAIE-KELRETCIQKRLDTEILP 339 +VTGA G IG + ++++ + + + L+++ Y + K+ R + L Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDY--YDVSLKQAR----LELLAQPGFQ 55 Query: 340 FL-GSVQNRTLLEHVMTAFSVATVYHAAAYKHVPMVEFNTVEGIRNNIFGTLECALAATT 398 F + +R + + + V+ + V N +N+ G L Sbjct: 56 FHKIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRH 115 Query: 399 SGVRTFVLIST---------------DKAVRPTNTMGASKRMAELCLQALAAEPGQKTRF 443 + ++ + S+ D P + A+K+ EL + G Sbjct: 116 NKIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPA-- 173 Query: 444 SMVRFGNVLGSSGS---VVPLFEKQIAEGGPLTL-THPEITRYFMTIPEAAQLVIQA 496 + +RF V G G + F K + EG + + + ++ R F I + A+ +I+ Sbjct: 174 TGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRL 230
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.0 bits (70), Expect = 0.002 Identities = 11/28 (39%), Positives = 17/28 (60%) Query: 121 EIEAEKSGTVKEILVENGTPVEFGEPLF 148 EI+ ++ VKEI+V+ G V G+ L Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLL 125
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 38.8 bits (90), Expect = 2e-06 Identities = 21/75 (28%), Positives = 30/75 (40%), Gaps = 5/75 (6%) Query: 69 IATAPECRRQGIASALLEY---WFTHLPEDTQRLLLEVRAGNTAAQALYTAHGFSITGRR 125 IA A + R++G+ +ALL W L+LE + N +A Y H F I Sbjct: 95 IAVAKDYRKKGVGTALLHKAIEWAKENH--FCGLMLETQDINISACHFYAKHHFIIGAVD 152 Query: 126 KNYYRTADGKTEDAV 140 Y E A+ Sbjct: 153 TMLYSNFPTANEIAI 167
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 48.4 bits (115), Expect = 1e-08 Identities = 36/172 (20%), Positives = 64/172 (37%), Gaps = 7/172 (4%) Query: 27 VSAASASAATLTVPTARGDAVVPKNPERVAVYDWAALDTLTELGVN-VG-ATTAPVRVDY 84 ++A + S + TA A+ +P R+ +W ++ L LG+ G A T R+ Sbjct: 13 LTAMALSPLLWQMNTAHAAAI---DPNRIVALEWLPVELLLALGIVPYGVADTINYRLWV 69 Query: 85 LQPAFDKAAT-VGTLFEPDYEALHRYNPQLVITGGPGAEAYEQLAKNATTIDLTV-DNGN 142 +P + VG EP+ E L P ++ + E LA+ A D Sbjct: 70 SEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGRGFNFSDGKQ 129 Query: 143 IRTSGEKQMETLARIFGKEARAAELKAQIDALFAQTREAAKGKGRGLVLSVT 194 K + +A + ++ A AQ + + +G +L T Sbjct: 130 PLAMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTT 181
>SECGEXPORT#Protein-export SecG membrane protein signature. Length = 110 Score = 116 bits (291), Expect = 3e-37 Identities = 40/107 (37%), Positives = 70/107 (65%), Gaps = 7/107 (6%) Query: 4 FKTLIWIVNIISALAVIVLVLLQHGKGADAGATFGSGSGSAQGVFGSAGNANFLSRSTAV 63 ++ L+ +V +I A+ ++ L++LQ GKGAD GA+FG+G+ + +FGS+G+ NF++R TA+ Sbjct: 2 YEALL-VVFLIVAIGLVGLIMLQQGKGADMGASFGAGASAT--LFGSSGSGNFMTRMTAL 58 Query: 64 AATFFFATCMAMVYIHTHTTKHGLDFSNVQQTQQAPKPVSNTEPSAP 110 AT FF + + I+++ T G ++ N+ AP T+P+AP Sbjct: 59 LATLFFIISLVLGNINSNKTNKGSEWENL----SAPAKTEQTQPAAP 101
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 30.1 bits (68), Expect = 0.037 Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 9/75 (12%) Query: 264 GATYVAVAAEHPLAAAAAADKPELQA---FIAECKAGSVAEADMATMEKKGVPTGRYVVN 320 GA V + E P+AAA A P +A + + G+ ++A + GV V Sbjct: 134 GAREVFLIEE-PMAAAIGAGLPVSEATGSMVVDIGGGTT---EVAVISLNGVVYSSSV-- 187 Query: 321 PLNGDKLEVWIANYV 335 + GD+ + I NYV Sbjct: 188 RIGGDRFDEAIINYV 202
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 25.9 bits (57), Expect = 0.044 Identities = 13/89 (14%), Positives = 29/89 (32%), Gaps = 3/89 (3%) Query: 25 FAGFLSAVGGGLSYLLPTFVA-VLLLKLFRGNPFLQ-SRMFVFGEILKVVLSLLSMLAVF 82 L A+ + + + + NP R+F +++ + S+L ++ + Sbjct: 92 TVAALMAIASHVVQYGFLISGEAIKPDIKKINPIEGAKRIFSIKSLVEFLKSILKVVLLS 151 Query: 83 AI-WHQSLVFAPFLMGLLGVSHLVFLVLL 110 + W L+ L LL Sbjct: 152 ILIWIIIKGNLVTLLQLPTCGIECITPLL 180
>PF04183#IucA / IucC family Length = 580 Score = 28.7 bits (64), Expect = 0.031 Identities = 19/89 (21%), Positives = 32/89 (35%), Gaps = 6/89 (6%) Query: 71 REHGLSRYELIAGERRWR-AAQIA--GLTEIPAVIKTISDETALAMGLIENLQRENLNPI 127 G RY + +WR A+ G I A +DE LA L+ L++ + + Sbjct: 30 ESQGDDRYCINLPGAQWRFIAERGIWGWLWIDAQTLRCADEPVLAQTLLMQLKQ--VLSM 87 Query: 128 EEAQGLKRLADEFGLTHETIAQAVGKSRS 156 +A + + T Q + R Sbjct: 88 SDAT-VAEHMQDLYATLLGDLQLLKARRG 115
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 245 bits (626), Expect = 1e-83 Identities = 68/219 (31%), Positives = 101/219 (46%), Gaps = 10/219 (4%) Query: 5 AYAFLLLIGFASAPAFAETRPADPYEGYNRAVFKFN-DQADRYIFAPAARGYRKVAPKPV 63 A LL+G AS+ + R +DP EG+NR ++ FN + D YI P A +R P+P Sbjct: 9 ALGTTLLVGCASSGTDQQGR-SDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWRDYVPQPA 67 Query: 64 RAGVSNFFNNLCDVVSFGSNILRLDIKRASEDLVRVGINTTFGLGGLIDIAGAGGIP--- 120 R G+SNF NL + + L+ D + R +NT G+GG ID+AG Sbjct: 68 RNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGMANPKLQR 127 Query: 121 DNKNTLGDTFASWGWKNSNYFVLPVLGPSTVRDALGTGITSVYSPKN-IVFRTPVGRWGT 179 + G T +G Y LP G T+RD G ++Y + + + VG+W Sbjct: 128 TEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMADALYPVLSWLTWPMSVGKW-- 185 Query: 180 TAVSAVSTREGLLDLTDSLDEAAIDKYSYTRDLYMKVRA 218 + + TR LLD +D L + D Y R+ Y + Sbjct: 186 -TLEGIETRAQLLD-SDGLLRQSSDPYIMVREAYFQRHD 222
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 76.8 bits (189), Expect = 5e-17 Identities = 60/366 (16%), Positives = 99/366 (27%), Gaps = 100/366 (27%) Query: 121 PAIEAGYTGRGVEVGIVDTGESVGSISFPELYGRKEHGYNENYKNYTAYMRKEAPEDGGG 180 PA+ GRGV+V ++DTG P+L R G N D Sbjct: 32 PAVWNQTRGRGVKVAVLDTG---CDADHPDLKARIIGGRNFT--------------DDDE 74 Query: 181 KDIEASFDDEAVIETEAKPTDIRHVKEIGHIDLVSHIIGGRSVDGRPAGGIAPDATLHIM 240 D E D GH V+ I + G+AP+A L I+ Sbjct: 75 GDPEIFKDYN------------------GHGTHVAGTIAATE-NENGVVGVAPEADLLII 115 Query: 241 NTNDETKNEMMVAAIRNAWVKLGERGVRIVNNSFGTTSRAGTADLFQIANSEEQYRQALL 300 ++ + I E+ V I++ S G Sbjct: 116 KVLNKQGSGQY-DWIIQGIYYAIEQKVDIISMSLG------------------------- 149 Query: 301 DYSGGDKTDEGIRLMQQSDYGNLSYHIRNKNMLFIFSTGNDAQAQPNTYALLPFYEKDAQ 360 + E ++ +L + + GN+ T Sbjct: 150 GPEDVPELHEAVK------------KAVASQILVMCAAGNEGDGDDRT---DELGYPGCY 194 Query: 361 KGIITVAGVDRSGEKFKREMYGEPGTEPLEYGSNHCGITAMWCLSAPYEASVRFTRTNPI 420 +I+V ++ + + + G + I + Sbjct: 195 NEVISVGAINFDRHASEFSNSN-NEVDLVAPGED---ILSTVPGGKYAT----------- 239 Query: 421 QIAGTSFSAPIVTGTAALLLQKYPW-----MSNDNLRTTLLTTAQDIGAVGVDSKFGWGL 475 +GTS + P V G AL+ Q ++ L L+ +G G GL Sbjct: 240 -FSGTSMATPHVAGALALIKQLANASFERDLTEPELYAQLIKRTIPLG--NSPKMEGNGL 296 Query: 476 LDAGKA 481 L Sbjct: 297 LYLTAV 302
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 35.6 bits (82), Expect = 4e-04 Identities = 31/158 (19%), Positives = 53/158 (33%), Gaps = 46/158 (29%) Query: 206 LEIAAAGGHSLLMMGPPGTGKSMLSQRLPGILPPLTEDELVEVWALRSLLPNHQQQLDSN 265 L +L++ G GTGK ++++ L H N Sbjct: 153 LARLMQTDLTLMITGESGTGKELVARAL------------------------HDYGKRRN 188 Query: 266 RPFRSPHHSASAAAMVG------------GGSDPRPGEISLAHHGVLFLDEL----PEFD 309 PF + + +A ++ G G A G LFLDE+ + Sbjct: 189 GPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQ 248 Query: 310 RKVLEVLREPLENGEIHISRAARQAVYPAKFQLVAAMN 347 ++L VL++ GE + + ++VAA N Sbjct: 249 TRLLRVLQQ----GEYT--TVGGRTPIRSDVRIVAATN 280
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 37.7 bits (87), Expect = 5e-05 Identities = 27/171 (15%), Positives = 60/171 (35%), Gaps = 7/171 (4%) Query: 44 IPASSKQPAETEILKPKNQPKEDIQPEPADQNALSEPDAATEAEQSDAEKAADKQPVADK 103 + A+++ + + + E A + TE Q + + P ++ Sbjct: 1076 VKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQ 1135 Query: 104 ADEVEEKAGEPEREEPDGQAVRKKALTEEREQTVREKAQKKDAETVKKQAVKPSKETEKK 163 ++ V+ +A EP RE +++ + A++ + +Q V S Sbjct: 1136 SETVQPQA-EPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNV--EQPVTESTTVNTG 1192 Query: 164 ASKEEKKAAKEKVAPKPTPEQILNSGSIEKARSAAAKEVQKMKTSDKAEAT 214 S E +PT +NS S K ++ + V+ + + + T Sbjct: 1193 NSVVENPENTTPATTQPT----VNSESSNKPKNRHRRSVRSVPHNVEPATT 1239 Score = 37.4 bits (86), Expect = 6e-05 Identities = 31/174 (17%), Positives = 56/174 (32%), Gaps = 7/174 (4%) Query: 40 NAFKIPASSKQPAETEILKPKNQPKEDIQPEPADQNALSEPDAATEAEQSDAEKAADKQP 99 N + S EI + P P PA + +E A ++S + ++ Sbjct: 1001 NNIQADVPSVPSNNEEIARVDEAPVPP--PAPATPSETTETVAENSKQESKTVEKNEQDA 1058 Query: 100 VADKADEVEEKAGEPEREEPDGQAVRKKALTEEREQTVREKAQKKDAETVKKQAVKPSKE 159 A E + + Q E ++T + + K+ TV+K+ K E Sbjct: 1059 TETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKET--QTTETKETATVEKEE-KAKVE 1115 Query: 160 TEKKASKEEKKAAKEKV-APKPTPEQILNSGSIEKARSAAAKEVQKMKTSDKAE 212 TEK + K ++ + Q + E + KE Q + Sbjct: 1116 TEKTQ-EVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADT 1168
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 31.2 bits (70), Expect = 0.009 Identities = 12/34 (35%), Positives = 21/34 (61%) Query: 152 KNLIQARAPEASQKVVHLTALPEAFDGIIIGNEV 185 +N+IQ + +K L + ++F GIIIGN++ Sbjct: 143 ENIIQPPILDDKEKAEFLKSAKQSFAGIIIGNQI 176
>56KDTSANTIGN#Rickettsia 56kDa type-specific antigen protein signature. Length = 533 Score = 25.7 bits (56), Expect = 0.028 Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 7/44 (15%) Query: 26 NQYRLNFTALDKAKKQEIALEQDYAQMRLQQARLANHEAIRAAA 69 NQ LNF +A++Q+ Q + QQA+ EA+ AAA Sbjct: 328 NQIHLNFVMPPQAQQQQ-------GQGQQQQAQATAQEAVAAAA 364
>PF05860#haemagglutination activity domain. Length = 117 Score = 82.2 bits (203), Expect = 2e-20 Identities = 24/139 (17%), Positives = 46/139 (33%), Gaps = 24/139 (17%) Query: 80 IIADKSAPKNQQAVILQTANGLPQVNIQTPSSQGVSVNRFKQFDVDEKGVILNNSRSNTQ 139 I D + P N T + T + + + F++F V G N+ +N Q Sbjct: 3 ITPDTTLPINSNIT---TEGNTRIIERGTQAGSNLFHS-FQEFSVPTSGTAFFNNPTNIQ 58 Query: 140 TQLGGWIQGNPHLARGEARVIVNQIDSSNPSLLNGYIEVGGKRAEVVVANPSGIRVNGGG 199 I++++ + S ++G I A + + NP+GI Sbjct: 59 -------------------NIISRVTGGSVSNIDGLIRANA-TANLFLINPNGIIFGQNA 98 Query: 200 LINAASVTLTSGVPVLNNG 218 ++ + S L Sbjct: 99 RLDIGGSFVGSTANRLKFA 117
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1178 bits (3048), Expect = 0.0 Identities = 510/1046 (48%), Positives = 693/1046 (66%), Gaps = 18/1046 (1%) Query: 1 MAKFFIDRPIFAWVISIFIIAAGIFGIKSLPVSQYPSVAAPTITLRATYPGASAQVMEDS 60 MA FFI RPIFAWV++I ++ AG I LPV+QYP++A P +++ A YPGA AQ ++D+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VLSVIERNMNGVEGLDYMSTSADSSGSGSVSLTFTPDTDENLAQVEVQNKLSEVLSTLPA 120 V VIE+NMNG++ L YMS+++DS+GS +++LTF TD ++AQV+VQNKL LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 TVQQYGVTVSKARSNFLMIVMLSSDVQST--EEMNDYAQRNIVPELQRIEGVGQVRLFGA 178 VQQ G++V K+ S++LM+ SD T ++++DY N+ L R+ GVG V+LFGA Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 179 QRAMRIWVDPKKLQNYNLSFADVGSALSAQNVQISAGSIGSLPAVRGQTVTATVTAQGQL 238 Q AMRIW+D L Y L+ DV + L QN QI+AG +G PA+ GQ + A++ AQ + Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 239 GTAEEFGNVILRANTDGSNVYLKDVARVGLGMEDYSSSTRLNGVNTTGMAVMLSNSGNAM 298 EEFG V LR N+DGS V LKDVARV LG E+Y+ R+NG G+ + L+ NA+ Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 299 ATAKAVKERMATLEKYFPQGMSWKTPYDTSKFVEISIEKVIHTLIEAMVLVFVVMYLFLQ 358 TAKA+K ++A L+ +FPQGM PYDT+ FV++SI +V+ TL EA++LVF+VMYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 359 NIRYTLIPTIVVPISLLGGFAFISYMGMSINVLTMFAMVLVIGIVVDDAIVVVENVERIM 418 N+R TLIPTI VP+ LLG FA ++ G SIN LTMF MVL IG++VDDAIVVVENVER+M Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 419 AGEGLPPKEATKKAMGQISGAVIGITAVLISVFVPLAMFSGATGNIYKQFALTMASSIAF 478 + LPPKEAT+K+M QI GA++GI VL +VF+P+A F G+TG IY+QF++T+ S++A Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 479 SAFLALTLTPALCATMLKTIPKGHHEEKKGFFGWFNKKFNSWTHGYEGRVAKVLRKTFRM 538 S +AL LTPALCAT+LK + HHE K GFFGWFN F+ + Y V K+L T R Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 Query: 539 MVVYIGLAVVGVFLFMRLPTSFLPTEDQGFVMVSVQLPAGATQERTNATLAQVTQ--LAK 596 +++Y + V LF+RLP+SFLP EDQG + +QLPAGATQERT L QVT L Sbjct: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 Query: 597 SIPEIENIITVSGFSFSGSGQNMAMGFAILKDWNERTAPGSDAVAIAGKLTGMMMGTLKD 656 +E++ TV+GFSFSG QN M F LK W ER + A A+ + M +G ++D Sbjct: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAK-MELGKIRD 659 Query: 657 GFGIAVVPPPILELGNGSGLSINLQDRNNTGHTALLAKRNELIQKMRASGLFDPSTVRAG 716 GF I P I+ELG +G L D+ GH AL RN+L+ A +VR Sbjct: 660 GFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMA-AQHPASLVSVRPN 718 Query: 717 GLEDSPQLKIDINRAAAAAQGISFADIRTALASALSSSYVSDFPNQGRLQRVMVQADEDA 776 GLED+ Q K+++++ A A G+S +DI +++AL +YV+DF ++GR++++ VQAD Sbjct: 719 GLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKF 778 Query: 777 RMQPADILNLTVPNKSGVAVPLSTIATVSWENGTEQSVRFNGYPSMKLSASPATGVSTGQ 836 RM P D+ L V + +G VP S T W G+ + R+NG PSM++ A G S+G Sbjct: 779 RMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGD 838 Query: 837 AMAAVQKMVDELGGGYSLEWGGQSREEAKGGSQTLILYGLAVAAVFLVLAALYESWSIPL 896 AMA ++ + +L G +W G S +E G+Q L ++ VFL LAALYESWSIP+ Sbjct: 839 AMALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPV 898 Query: 897 AVILVIPLGLIGAAAGVTGRNLFEGLLGSVPSFANDIYFQVGFVTVMGLSAKNAILIIEF 956 +V+LV+PLG++G T N ND+YF VG +T +GLSAKNAILI+EF Sbjct: 899 SVMLVVPLGIVGVLLAATLFN-----------QKNDVYFMVGLLTTIGLSAKNAILIVEF 947 Query: 957 AKDLQ-AQGKSAVEAALEAARLRFRPIIMTSFAFILGVVPLYIAGGASSASQRAIGTTVF 1015 AKDL +GK VEA L A R+R RPI+MTS AFILGV+PL I+ GA S +Q A+G V Sbjct: 948 AKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVM 1007 Query: 1016 WGMLIGTLLSVFLVPLFYVVVRKFFK 1041 GM+ TLL++F VP+F+VV+R+ FK Sbjct: 1008 GGMVSATLLAIFFVPVFFVVIRRCFK 1033 Score = 88.0 bits (218), Expect = 1e-19 Identities = 100/538 (18%), Positives = 189/538 (35%), Gaps = 60/538 (11%) Query: 532 LRKTFRMMVVYIGLAVVGVFLFMRLPTSFLPTEDQGFVMVSVQLPAGATQERTNATLAQV 591 +R+ V+ I L + G ++LP + PT V VS P GA + T+ QV Sbjct: 6 IRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYP-GADAQTVQDTVTQV 64 Query: 592 TQLAKSIPEIENIITVSGFSFSGSGQNMAMGFAILKDWNERTAPGSDAVAIAGKLTGMMM 651 + +++ I+N++ +S S S + + F D + + + +A Sbjct: 65 --IEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLA-------T 115 Query: 652 GTLKDGFGIAVVPPPILELGNGSGLSI----NLQDRNNTGHTAL--LAKRNELIQKMRAS 705 L V + + S + + D T + N R + Sbjct: 116 PLLPQE-----VQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLN 170 Query: 706 GLFDPSTVRAGGLEDSPQLKIDINRAAAAAQGISFADIRTALASA---LSSSYVSDFPNQ 762 G+ D G ++I ++ ++ D+ L +++ + P Sbjct: 171 GVGDVQLF--GA---QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPAL 225 Query: 763 GRLQRVMVQADEDARMQ-PADILNLTVP-NKSGVAVPLSTIATVSWENGTEQ---SVRFN 817 Q++ R + P + +T+ N G V L +A V E G E R N Sbjct: 226 PG-QQLNASIIAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARV--ELGGENYNVIARIN 282 Query: 818 GYPSMKLSASPATGVSTGQAMAAVQKMVDELGGG--------YSLEWGGQSREEAKGGSQ 869 G P+ L ATG + A++ + EL Y + + + Sbjct: 283 GKPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVK 342 Query: 870 TLILYGLAVAAVFLVLAALYESWSIPLAVILVIPLGLIGAAAGVTGRNLFEGLLGSVPSF 929 TL A+ VFLV+ ++ L + +P+ L+G A + G + + Sbjct: 343 TLFE---AIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAIL----AAFGYSINTLTM 395 Query: 930 ANDIYFQVGFVTVMGLSAKNAILIIE-FAKDLQAQGKSAVEAALEAARLRFRPIIMTSFA 988 G V +GL +AI+++E + + EA ++ ++ + Sbjct: 396 F-------GMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMV 448 Query: 989 FILGVVPLYIAGGASSASQRAIGTTVFWGMLIGTLLSVFLVPLFYVVVRKFFKETAHE 1046 +P+ GG++ A R T+ M + L+++ L P + K HE Sbjct: 449 LSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHE 506
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 49.1 bits (117), Expect = 2e-08 Identities = 25/197 (12%), Positives = 69/197 (35%), Gaps = 29/197 (14%) Query: 71 RTADVRAQVGGIIQKRLFQEGSYVRAGQPLYQIDSSTYEAGLESARAQLATAQATLAKAD 130 R+ +++ I+++ + +EG VR G L ++ + EA ++ L A+ + Sbjct: 95 RSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQ 154 Query: 131 A---------------------DLARYKPLVAAEAVSRQEYDAAVTAKRSAEAGVKAAQA 169 + ++ ++ ++++ K E + +A Sbjct: 155 ILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRA 214 Query: 170 AIKSAGISLNRSRITAPISGFIGQSKVSE-GTLLNAGDAT---VLATIRQTNPMYVNVTQ 225 + +NR + + +S++ + +LL+ VL + + Sbjct: 215 ERLTVLARINRYENLSRVE----KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRV 270 Query: 226 SASEVMKLRRQIAEGKL 242 S++ ++ +I K Sbjct: 271 YKSQLEQIESEILSAKE 287 Score = 32.9 bits (75), Expect = 0.003 Identities = 17/150 (11%), Positives = 42/150 (28%), Gaps = 44/150 (29%) Query: 102 QIDSSTYEAGLESARAQLATAQATLAKADADLARYKPLVAAEAVSRQEY----------- 150 +++ A + A++ + + L + L+ +A+++ Sbjct: 206 ELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAV 265 Query: 151 -DAAVTAKRSAEAGVKAAQAAIK-------------------------------SAGISL 178 + V + + + A + Sbjct: 266 NELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQ 325 Query: 179 NRSRITAPISGFIGQSKV-SEGTLLNAGDA 207 S I AP+S + Q KV +EG ++ + Sbjct: 326 QASVIRAPVSVKVQQLKVHTEGGVVTTAET 355 Score = 32.1 bits (73), Expect = 0.004 Identities = 14/53 (26%), Positives = 23/53 (43%), Gaps = 1/53 (1%) Query: 52 VHPQTVALTVELPGRLESLRTADVRAQVGGIIQK-RLFQEGSYVRAGQPLYQI 103 LT+EL E + + +RA V +Q+ ++ EG V + L I Sbjct: 307 TTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVI 359
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 135 bits (340), Expect = 7e-42 Identities = 70/208 (33%), Positives = 107/208 (51%) Query: 1 MRKTKTEALKTKEHLMLAALETFYRKGIARTSLNEIAQAAGVTRGALYWHFKNKEDLFDA 60 RKTK EA +T++H++ AL F ++G++ TSL EIA+AAGVTRGA+YWHFK+K DLF Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 61 LFQRICDDIENCIAQDAEDAEGGSWAVFRHTLLHFFERLQSNDIYYKFHNILFLKCEHTE 120 +++ +I + G +V R L+H E + + I+F KCE Sbjct: 62 IWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVG 121 Query: 121 QNAAVIAIARKHQAIWREKITAVLTEAVENQDLADDLDKETAVIFIKSTLDGLIWRWFSS 180 + A V R ++I L +E + L DL A I ++ + GL+ W + Sbjct: 122 EMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFA 181 Query: 181 CERFDLGKTAPRIIGIMMDNLENHPDLR 208 + FDL K A + I+++ P LR Sbjct: 182 PQSFDLKKEARDYVAILLEMYLLCPTLR 209
>LUXSPROTEIN#Bacterial autoinducer-2 (AI-2) production protein LuxS signature. Length = 171 Score = 277 bits (709), Expect = 5e-99 Identities = 132/165 (80%), Positives = 148/165 (89%) Query: 2 PLLDSFKVDHTRMHAPAVRVAKTMTTPKGDTITVFDLRFCVPNKEILPGKGIHTLEHLFA 61 PLLDSF VDHTRM+APAVRVAKTM TPKGDTITVFDLRF PNK+IL KGIHTLEHL+A Sbjct: 1 PLLDSFTVDHTRMNAPAVRVAKTMQTPKGDTITVFDLRFTAPNKDILSEKGIHTLEHLYA 60 Query: 62 GFMRDHLNGNGVEIIDISPMGCRTGFYMSLIGTPSEQQVADAWLASMQDVLNVKDQSKIP 121 GFMR+HLNG+ VEIIDISPMGCRTGFYMSLIGTPSEQQVADAW+A+M+DVL V++Q+KIP Sbjct: 61 GFMRNHLNGDSVEIIDISPMGCRTGFYMSLIGTPSEQQVADAWIAAMEDVLKVENQNKIP 120 Query: 122 ELNEYQCGTYQMHSLAEAQQIAQNVLARKVAVNKNEELTLDEGLL 166 ELNEYQCGT MHSL EA+QIA+N+L VAVNKN+EL L E +L Sbjct: 121 ELNEYQCGTAAMHSLDEAKQIAKNILEVGVAVNKNDELALPESML 165
>ENTEROTOXINA#Heat-labile enterotoxin A chain signature. Length = 258 Score = 31.1 bits (70), Expect = 0.015 Identities = 27/83 (32%), Positives = 34/83 (40%), Gaps = 17/83 (20%) Query: 360 TTSLDAMNASLVGISIAFQAGEAVYIPVGHSLTAAPEQLDLQDVLGRLKPHLGNPALKKI 419 +TSL +A L G SI YI V + AP ++ DVLG PH Sbjct: 79 STSLSLRSAHLAGQSI-LSGYSTYYIYV---IATAPNMFNVNDVLGVYSPH--------- 125 Query: 420 GQNLKYDQHVFANYGIALNGIAG 442 Y+Q V A GI + I G Sbjct: 126 ----PYEQEVSALGGIPYSQIYG 144
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 793 bits (2050), Expect = 0.0 Identities = 337/1203 (28%), Positives = 537/1203 (44%), Gaps = 188/1203 (15%) Query: 22 RFSPAYLAICLSFGILPQAWAGHTYFGINYQYYRDFAENKGKFAVGAKDIEVYNKKGELV 81 +F ++A+ +++ + P A ++YQ +RDFAENKGKF+VGA ++ V +K + + Sbjct: 5 KFKLNFIALTVAYALTPYTEAALVRDDVDYQIFRDFAENKGKFSVGATNVLVKDKNNKDL 64 Query: 82 GKSMTKA-PMIDFSVVSRN-GVAALVGDQYIVSVAH-NGGYNNVDFG-----AEGRNPDQ 133 G ++ PMIDFSVV + +A L+ QY+V V H + G + + FG N Sbjct: 65 GTALPNGIPMIDFSVVDVDKRIATLINPQYVVGVKHVSNGVSELHFGNLNGNMNNGNAKA 124 Query: 134 HRFT------YKIVKRNNY---------KAGTKGHPYGGDYHMPRLHKFVTDAEPVEMTS 178 HR Y V++N Y + DY+MPRL KFVT+ P+E ++ Sbjct: 125 HRDVSSEENRYFSVEKNEYPTKLNGKTVTTEDQTQKRREDYYMPRLDKFVTEVAPIEAST 184 Query: 179 Y-MDGRKYIDQNNYPDRVRIGAGRQYWRSDEDEPNNRESSYH--------IASAYSWLVG 229 D Y DQN YP VR+G+G Q+ D + +++ + AY++ + Sbjct: 185 ASSDAGTYNDQNKYPAFVRLGSGSQFIYKKGDNYSLILNNHEVGGNNLKLVGDAYTYGIA 244 Query: 230 GNTFAQNGSGGGTVNLGSEKIKHSP------YGFLPTGGSFGDSGSPMFIYDAQKQKWLI 283 G + N G + G+ K +HS L GDSGSP+F+YD +K KWL Sbjct: 245 GTPYKVNHENNGLIGFGNSKEEHSDPKGILSQDPLTNYAVLGDSGSPLFVYDREKGKWLF 304 Query: 284 NGVLQTGNPYIGKSNGFQLVRKDWFYDEIFAGDTHSVFYEPRQNGKYSFNDDNNGTGKIN 343 G Y + ++ Y F D N D+ G+ + Sbjct: 305 LGSYDFWAGY-----NKKSWQEWNIYKSQFTKDV--------------LNKDSAGSLIGS 345 Query: 344 AKHEHNSLPNRLKTRTVQLFNVSLSETAREPVYHAAGGVNSYRPRLNNGENISFIDEGKG 403 S KT T+ SL+ A G + + N+G++++F EG G Sbjct: 346 KTDYSWSSNG--KTSTITGGEKSLN-------VDLADG----KDKPNHGKSVTF--EGSG 390 Query: 404 ELILTSNINQGAGGLYFQGDFTVSPE-NNETWQGAGVHISEDSTVTWKVNGVANDRLSKI 462 L L +NI+QGAGGL+F+GD+ V +N TW+GAGV ++E TVTWKV+ DRL+KI Sbjct: 391 TLTLNNNIDQGAGGLFFEGDYEVKGTSDNTTWKGAGVSVAEGKTVTWKVHNPQYDRLAKI 450 Query: 463 GKGTLHVQAKGENQGSISVGDGTVILDQQADDKGKKQAFSEIGLVSGRGTVQLNADNQFN 522 GKGTL V+ G+N+GS+ VGDGTVIL QQ + G+ AF+ +G+VSGR T+ LN D Q + Sbjct: 451 GKGTLIVEGTGDNKGSLKVGDGTVILKQQTNGSGQ-HAFASVGIVSGRSTLVLNDDKQVD 509 Query: 523 PDKLYFGFRGGRLDLNGHSLSFHRIQNTDEGAMIVNHNQDKESTVTITGNKDIA-----T 577 P+ +YFGFRGGRLDLNG+SL+F I+N D+GA +VNHN S +TITG I T Sbjct: 510 PNSIYFGFRGGRLDLNGNSLTFDHIRNIDDGARLVNHNMTNASNITITGESLITDPNTIT 569 Query: 578 TGNNNSLDSKKEIAYNGWFGEKDTTKTNGRLNLVYQPAAEDRTLLLSGGTNLNGNITQTN 637 N ++ D A+ K G+L L + L G + + + + Sbjct: 570 PYNIDAPDEDNPYAFRR-------IKDGGQLYLNLENY---TYYALRKGASTRSELPKNS 619 Query: 638 GK----LFFSGRPTPHA----YNHLND-HWSQKEGIPRGEIVWDNDWINRTFKAEN---- 684 G+ + G+ + A NH+N+ + G E +N +N TFK ++ Sbjct: 620 GESNENWLYMGKTSDEAKRNVMNHINNERMNGFNGYFGEEEGKNNGNLNVTFKGKSEQNR 679 Query: 685 FQIKGGQAVVSRNVAKVKGDWHLSNHAQAVFG-VAPHQSHT--ICTRSDWTGLTNCVEKT 741 F + GG + GD + + G PH I + E Sbjct: 680 FLLTGG--------TNLNGDLTVEKGTLFLSGRPTPHARDIAGISSTKKDPHFAENNEVV 731 Query: 742 ITDDKVIASLTKTDISGNVDLADHAHLNLTGLATLNGNLSANGDTRYTVSHNATQNGNLS 801 + DD + + T ++ + + ++ N +A + N++A+ + + + + Sbjct: 732 VEDDWINRNFKATTMNVTGNASLYSGRN---VANITSNITASNKAQVHIGYKTGDTVCVR 788 Query: 802 LVGNAQATFNQATLNGNTSASGNASFNLSDHAVQNGSLTLSGNAKANVSHSALNGNVSLA 861 T LSD A+ + + + L GNV+L Sbjct: 789 SDYTGYVTCTTD--------------KLSDKAL------------NSFNPTNLRGNVNLT 822 Query: 862 DKAVFHFESSRFTGQISGGKDTALHLK-DSEWTLPSGTELGNLNLDNATITLNSAYRHDA 920 + A F + G I ++ + L +S W L +++ L+L N I LNSA Sbjct: 823 ESANFVLGKANLFGTIQSRGNSQVRLTENSHWHLTGNSDVHQLDLANGHIHLNSA----- 877 Query: 921 AGAQTGSATDAPRRRSRRSRRSLLSVTPPTSVESRFNTLTVNGKLNGQGTFRFMSELFGY 980 ++ + ++NTLTVN L+G G+F ++++L Sbjct: 878 -----DNSNNVT----------------------KYNTLTVN-SLSGNGSFYYLTDLSNK 909 Query: 981 RSDKLKLAESSEGTYTLAVNNTGNEPASLEQLTVVEGKDNKPLSENLNFTLQNEHVDAGA 1040 + DK+ + +S+ G +TL V + EP + +LT+ + +K ++LN +L VD GA Sbjct: 910 QGDKVVVTKSATGNFTLQVADKTGEP-NHNELTLFDA--SKAQRDHLNVSLVGNTVDLGA 966 Query: 1041 WRYQLIRKDGEFRLHNPVKEQELSDKLGKAE-----AKKQAEKDNAQSLDALIAAGRDAV 1095 W+Y+L +G + L+NP E E ++ QA+ + S + IA +A Sbjct: 967 WKYKLRNVNGRYDLYNP--EVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAP 1024 Query: 1096 EKTESVAEPARQA--GGENVGIMQAEEEKKRVQADKDTALAKQREAETRPATTAFPRARR 1153 + A P+ EN EK A + TA ++ E + A + Sbjct: 1025 VPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNE 1084 Query: 1154 ARR 1156 + Sbjct: 1085 VAQ 1087
>PF05272#Virulence-associated E family protein Length = 892 Score = 33.5 bits (76), Expect = 0.002 Identities = 20/82 (24%), Positives = 31/82 (37%), Gaps = 7/82 (8%) Query: 181 IDFLEAADARGKLDGLR--RAVDDVLANAQQGAILREGLNV----VLVGAPNVGKSSLLN 234 + L K LR + V + ++ G VL G +GKS+L+N Sbjct: 555 VHVLGKTPDDYKPRRLRYLQLVGKYILMGHVARVMEPGCKFDYSVVLEGTGGIGKSTLIN 614 Query: 235 ALAGDEVAIVTDI-AGTTRDAV 255 L G + T GT +D+ Sbjct: 615 TLVGLDFFSDTHFDIGTGKDSY 636
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 53.8 bits (129), Expect = 2e-10 Identities = 34/163 (20%), Positives = 65/163 (39%), Gaps = 7/163 (4%) Query: 57 QNPERIAVYDLGMLDTLSKLGVK-TGLSVDKNRLPYLEE--YFKTTKPAGTLFEPDYETL 113 +P RI + ++ L LG+ G++ N ++ E + G EP+ E L Sbjct: 33 IDPNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSEPPLPDSVIDVGLRTEPNLELL 92 Query: 114 NAYKPQLIIIGSRAAKAFDKLNEIAPTIEMT-ADTANLKESAKERIDALAQIFGKQAEAD 172 KP ++ + + + L IAP +D A++ + +A + Q+ A+ Sbjct: 93 TEMKPSFMVWSAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNLQSAAE 152 Query: 173 KLKAEIDASFEAAKTAAQGKGKGLVILVN---GGKMSAFGPSS 212 A+ + + K +G ++L M FGP+S Sbjct: 153 THLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNS 195