List of
Environmental factors
and their associated regulons
Environmental factor
# Up regulated genes
# Down regulated genes
Acid-shock (10min)
218
231
Acid-shock (20min)
232
239
Acid-shock (2min)
69
47
Acid-shock (5min)
167
150
Anaerobic (10min)
0
0
Anaerobic (20min)
50
2
Anaerobic (30min)
69
32
Anaerobic (60min)
110
68
Bacitracin
148
58
Berberine Chloride
484
243
Biofilm Vs Planktonic (early)
10
7
Biofilm Vs Planktonic (mature)
8
10
Biofilm Vs Planktonic (maturing)
11
5
Biofilm Vs Planktonic 16hr
56
30
Biofilm Vs Planktonic 24hr
39
20
Biofilm Vs Planktonic 48hr
33
14
Biofilm Vs Planktonic 6hr
25
86
Biofilm Vs Planktonic 8hr
93
149
Biofilm Vs Planktonic OD 1.0
87
252
Biofilm Vs Planktonic OD 3.5
102
204
CCCP (ATCC 29213)
0
0
Cefoxitin (N315)
11
12
Cefoxitin (N315-SaeRSmutant)
0
6
Chlorination (10 min)
286
685
Chlorination (20 min)
123
560
Ciprofloxacin (120min)
49
63
Ciprofloxacin (30min)
37
30
Cold shock
66
342
D-Cycloserine
320
58
Daptomycin (ATCC 29213)
0
0
Fusidic acid stimulon
272
272
Glycopeptide resistance (14-4 Vs 14-4Rev)
36
27
Glycopeptide resistance (14-4 Vs MRGR3)
35
32
Heat shock
98
30
Hydrogen Peroxide 10min
112
151
Hydrogen Peroxide 20min
95
24
Mild Acid 0hr
92
80
Mild Acid 3hr
143
45
Mild Acid 6hr
143
54
Nisin (ATCC 29213)
0
0
Nitrite Stress
290
348
Nitrosative stress
65
18
Oxacillin
190
58
Oxacillin (SH1000)
0
0
Peracetic Acid 10min
223
233
Peracetic Acid 20min
271
127
Salicylate
25
15
SOS response
70
408
Stringent response
247
704
Teicoplanin resistance
31
18
Triclosan (0.05uM, 10Min)
0
4
Triclosan (0.05uM, 60Min)
20
71
Vancomycin (ATCC 29213)
0
0
Vancomycin (N315)
113
30
Vancomycin (N315-VraSRmutant)
77
22
Vancomycin resistance (HIP5827)
78
74
Vancomycin resistance (JH1)
47
23
Vancomycin resistance (Mu50)
86
64
Vancomycin resistance (Newman)
69
41
VISA Vs h-VISA (Mu50 Vs Mu3)
18
0
VISA Vs VSSA (MI Vs MI-P)
48
1
VISA Vs VSSA (MI-PR Vs MI-P)
65
1
VISA Vs VSSA (Mu50 Vs Mu50-P)
42
0
VISA Vs VSSA (Mu50 Vs N315)
45
0
VISA Vs VSSA (Mu50-PR Vs Mu50-P)
50
0
VRSA Vs VRSA (JH9 Vs JH14)
16
0
VRSA Vs VSSA (JH9 Vs JH1)
55
168
