Align
[Alignment-Contextmenu>Alignment] The Dialog is used to align a
number of selected proteins (see ent).
The user selects an alignment method
.
By pressing the button
the alignment
computation is started. It takes some seconds to minutes, before the
computation the result is shown in a preview panel.
To accept the alignment in the preview and to infer the alignment into
the working alignment panel
needs to be pressed to.
Types of alignment procedures:
So-called local alignment procedures identify local matches
whereas global alignment algorithms align the entire sequences.
Some alignment programs align two sequences only. The derived multiple
alignments are not as good as those from methods that
natively support multiple alignments.
3D-superposition programs consider only the 3D-structure and do not
regard the residue type.
Profiles: ClustalW and T-coffee can use pre-aligned
sequences as a so-called sequence profile. For more information
see the manual of T-coffee.