Align

[Alignment-Contextmenu>Alignment] The Dialog is used to align a number of selected proteins (see ent). The user selects an alignment method MultipleAlignerClustalW. By pressing the button ChButton#BUTTON_GO the alignment computation is started. It takes some seconds to minutes, before the computation the result is shown in a preview panel. To accept the alignment in the preview and to infer the alignment into the working alignment panel DialogAlignResult#BUT_LAB_Apply needs to be pressed to.

Types of alignment procedures: So-called local alignment procedures identify local matches whereas global alignment algorithms align the entire sequences. Some alignment programs align two sequences only. The derived multiple alignments are not as good as those from methods that natively support multiple alignments. 3D-superposition programs consider only the 3D-structure and do not regard the residue type.

Profiles: ClustalW and T-coffee can use pre-aligned sequences as a so-called sequence profile. For more information see the manual of T-coffee.