Ofloxacin
| DRUG INFORMATION |
| Drug Name |
| Ofloxacin |
 |
| Synonyms |
| ofloxacin, Ocuflox, Ofloxacine, Levaquin,Elequine, Zanocin, Oflocet, Oxaldin, Tarivid,Floxin, (ñ)-9- fluoro-2,3-dihydro-3-methyl-10- (4-methyl-1-piperazinyl)-7-oxo-7H- pyrido[1,2,3-de]-1,4-benzoxazine -6- carboxylic acid, ofloxacin, Ocuflox, Ofloxacine, Levaquin, Elequine, Zanocin, Oflocet, Oxaldin, Tarivid |
| Drug Class |
| Second-Line Drugs |
| Year of Introduction |
| 1987 |
| Molecular Target |
| DNA gyrase Rv0005 Rv0006 |
| Genes Involved in Drug Resistance |
| gyrA & gyrB |
| CAS No: |
| 83380-47-6 |
| PHARMACOLOGY |
| Route |
| oral |
| Toxicity |
| Low |
| Cost |
| High |
| STRUCTURAL DETAILS |
| Molecular Formula |
| C18H20FN3O4 |
| Molecular Weight in g/mol |
| 361.368 |
| Hydrogen Bond Donor Count |
| 1 |
| Hydrogen Bond Acceptor Count |
| 8 |
| Rotatable Bond Count |
| 2 |
| IUPAC Name |
| Not Available |
| SMILES |
| CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O |
| InChI |
| 1/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)/f/h24H |
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