Sparfloxacin
| DRUG INFORMATION |
| Drug Name |
| Sparfloxacin |
 |
| Synonyms |
| sparfloxacin, Zagam, Spara, Zagam (TN), Sparfloxacin (JAN/USP), Sparfloxacinum [INN-Latin], Sparfloxacine [INN-French], Esparfloxacino [INN-Spanish], CI 978, CI-978 |
| CAS No: |
| 111542-93-9 |
| PHARMACOLOGY |
| Route |
| Oral |
| Side effects |
| Frequent: photosensitivity (7.9% incidence rate) sunscreen may not protect against photosensitivity. Occasional: prolonged QT interval (without arrhythmia); GI intolerance; headache; malaise; insomnia; restlessness; dizzi ness. Rare: tendon rupture. |
| Usual Adult Dosage |
| CAP: 200mg po qd |
| Form |
| capsule |
| Brand Name |
| Zagam |
| Manufacturer |
| Zydus Cadila |
| STRUCTURAL DETAILS |
| Molecular Formula |
| C19H22F2N4O3 |
| Molecular Weight in g/mol |
| 392.4 |
| Hydrogen Bond Donor Count |
| 3 |
| Hydrogen Bond Acceptor Count |
| 9 |
| Rotatable Bond Count |
| 3 |
| IUPAC Name |
| : 5-amino-1-cyclopropyl-7-(3,5-dimethylpiperazin-1-yl)-6,8-difluoro-4-oxo-quinoline-3-carboxylic acid |
| SMILES |
| Isomeric SMILES: C[C@@H]1CN(C[C@@H](N1)C)C2=C(C3=C(C(=C2F)N)C(=O)C(=CN3C4CC4)C(=O)O)F |
| InChI |
| 1/C19H22F2N4O3/c1-8-5-24(6-9(2)23-8)17-13(20)15(22)12-16(14(17)21)25(10-3-4-10)7-11(18(12)26)19(27)28/h7-10,23H,3-6,22H2,1-2H3,(H,27,28)/t8-,9+/f/h27H |
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