| TARGET INFORMATION |
| Target Name |
| Enoyl-[acyl-carrier-protein] reductase [NADH] |
| Targeted By |
| isoniazid |
| Function |
| Involved in the resistance against the antituberculosis drugs isoniazid and ethionamide |
| Experimental Status |
| In PDB |
| PROTEOMIC INFORMATION |
| Molecular Weight of Protein Sequence |
| 28527.5508 |
| Protein Analysis [Predicted Results] |
| Isoelectric Antigenic Sites Tmap PepInfo Hydropathy Plot |
| Helical Wheel Pepplot Garnier H-T-H |
| Secondary Structure [Psipred Results] |
| Rv1484 |
| Amino Acid Sequence Length |
| 269 |
| Pdb Structure |
| 1enz
1eny
1bvr
1zid
1p44
1p45 |
| Amino acid Sequence |
| >sp|P0A5Y6|INHA_MYCTU Enoyl-[acyl-carrier-protein] reductase [NADH] (EC 1.3.1.9) (NADH- dependent enoyl-ACP reductase) - Mycobacterium tuberculosis.
MTGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPL
LELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGI
HISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAG
KYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAK
TVCALLSDWLPATTGDIIYADGGAHTQLL
|
| GENOMIC INFORMATION |
| Length of Nucleotide Sequence |
| 810 |
| Position |
| 1674202.....1675011 |
| GC Content |
| 0.6543 |
| Nucleotide Sequence |
| >
ATGACAGGACTGCTGGACGGCAAACGGATTCTGGTTAGCGGAATCATCACCGACTCGTCG
ATCGCGTTTCACATCGCACGGGTAGCCCAGGAGCAGGGCGCCCAGCTGGTGCTCACCGGG
TTCGACCGGCTGCGGCTGATTCAGCGCATCACCGACCGGCTGCCGGCAAAGGCCCCGCTG
CTCGAACTCGACGTGCAAAACGAGGAGCACCTGGCCAGCTTGGCCGGCCGGGTGACCGAG
GCGATCGGGGCGGGCAACAAGCTCGACGGGGTGGTGCATTCGATTGGGTTCATGCCGCAG
ACCGGGATGGGCATCAACCCGTTCTTCGACGCGCCCTACGCGGATGTGTCCAAGGGCATC
CACATCTCGGCGTATTCGTATGCTTCGATGGCCAAGGCGCTGCTGCCGATCATGAACCCC
GGAGGTTCCATCGTCGGCATGGACTTCGACCCGAGCCGGGCGATGCCGGCCTACAACTGG
ATGACGGTCGCCAAGAGCGCGTTGGAGTCGGTCAACAGGTTCGTGGCGCGCGAGGCCGGC
AAGTACGGTGTGCGTTCGAATCTCGTTGCCGCAGGCCCTATCCGGACGCTGGCGATGAGT
GCGATCGTCGGCGGTGCGCTCGGCGAGGAGGCCGGCGCCCAGATCCAGCTGCTCGAGGAG
GGCTGGGATCAGCGCGCTCCGATCGGCTGGAACATGAAGGATGCGACGCCGGTCGCCAAG
ACGGTGTGCGCGCTGCTGTCTGACTGGCTGCCGGCGACCACGGGTGACATCATCTACGCC
GACGGCGGCGCGCACACCCAATTGCTCTAG |