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Gene 1 | Gene 2 | Interaction Type | Sentence | Value | Judge me |
Smad3 | Smad4 | complex2 | Although Smad3 and Smad4 were not detectable in TGFbeta ( 3 ) -inducible AP-1 complexes at the TGFbeta ( 1 ) promoter , stable expression of dominant-negative Smad3 could significantly inhibit the abi | 9 | good bad |
Smad3 | Smad2 | interact2 | The vertebrate members of the MAD-related family , termed Smad2 and Smad3 , interact specifically with the TGF-beta type I receptor and are phosphorylated on the last two serines of a conserved C-term | 4 | good bad |
Smad3 | Axin | bind1 | Moreover , the transcriptional activity of TGF-beta was enhanced by Axin and repressed by an Axin mutant which is able to bind to Smad3 . | 2 | good bad |
Smad3 | Axin | interact1 | An Axin homologue , Axil ( also called conductin ) , also interacted with Smad3 . | 1 | good bad |
Smad3 | JNK | interact3 | This effect is not dependent on blocking of Smad3 nuclear translocation but involves a functional interaction between Smad3 and c-Jun , a transcription factor activated by the SAPK JNK pathway . | 1 | good bad |
Smad3 | JNK | interact3 | This effect is not dependent on blocking of Smad3 nuclear translocation but involves a functional interaction between Smad3 and c-Jun , a transcription factor activated by the SAPK JNK pathway . | 1 | good bad |
Smad3 | Axin | bind1 | Moreover , the transcriptional activity of TGF-beta was enhanced by Axin and repressed by an Axin mutant which is able to bind to Smad3 . | 0 | good bad |
Smad3 | Axin | interact1 | An Axin homologue , Axil ( also called conductin ) , also interacted with Smad3 . | 0 | good bad |
Smad3 | Smad2 | interact2 | The vertebrate members of the MAD-related family , termed Smad2 and Smad3 , interact specifically with the TGF-beta type I receptor and are phosphorylated on the last two serines of a conserved C-term | -1 | good bad |
Smad3 | Smad4 | associate1 | Activin stimulation triggered association of Dok-1 with Smad3 , as well as association of Smad3 with Smad4 . | -3 | good bad |
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Text2Knowledge ... Yong Huang
2002
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