Gary Van Domselaar
From Bioinformatics.Org Wiki
Protein Structure Quality Assessment
Protein structures can be determined experimentally by X-ray crystallography and NMR spectroscopy. But how close are the experimentally determined structures to the "real" structures? I am interested in developing algorithms and software for judging the quality of protein structures generated using NMR spectroscopy. I am writing a computer program called "NMRQ" for this purpose.
Automated Genome Annotation
The genomes of prokaryotes are being sequenced and made public at a furious rate. To help with the interpretation of this data, I wrote BASys, an automated prokaryotic genome annotation system. Anyone can submit their raw prokaryotic chromosome, plasmid, or contig data to BASys and it will attempt to identify and annotate the protein encoding regions.
I am a founding member and Associate Director of The Bioinformatics Organization, Inc.