BI221 Mitochondriomics

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Mitochondrial dysfunction has been correlated with diseases where clinical pathologies include infertility, diabetes, blindness, deafness, stroke, migraine, plus heart, kidney, and liver diseases. Recently, cancer was added to this list when investigations into human cancer cells from breast, bladder, neck and lung revealed a high occurrence of mutations in mtDNA. With the emerging understanding of the role of mitochondria in a vast array of pathologies, research into this organelle and its dysfunction has yielded a vast amount of data in the last decade in the form of publications and databases. Nevertheless, the field of mitochondrial research is still far from exhausted, with many unknown factors yet to be discovered.

The purpose of this course is to introduce the student to the various databases and wet-lab methods available. Furthermore, the course will, through selected articles, give an understanding of the pitfalls and limitations of such resources.


Prashanth Suravajhala

Additionally, Claus Desler will give a lecture as supplementary material for the course.


April 4-8, 2011, Monday/Wednesday/Friday

There will be 2 hours of lecture for each of the 3 days. This course will also include about an hour of supplemental lectures.

Session 1
Introduction to mitochondria and its pathways and genetics, by Prash Suravajhala
Session 2
Proteomics of mitochondria, by Prash Suravajhala
Biochemistry of mitochondrial diseases, by Claus Desler
Various assays used and advances in mitochondrial research
Session 3
Tools and databases used in mitochondrial research, by Prash Suravajhala
Session 4
Challenges in mitochondrial research, by Prash Suravajhala
Session 5
Mitochondria in aging and diseases, Prash Suravajhala
Session 6
Exercises & take home messages, by Prash Suravajhala

Scheduled courses

If you are interested in an upcoming course, register using instructions below. (Access to completed courses is available to enrolled students only, because of privacy and confidentiality issues.)


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Please also check the course tuition rates and discounts.

Registration deadline: When full

Tuition & discounts

Live instruction held on-line
Live instruction held on-site
On-demand instruction held on-line

Additional discounts are available as follows:


The necessary software, lecture notes and exercises will be provided.

Live instruction held on-line

On-line/live courses use the WebEx on-line meeting system. Access information will be provided prior to the start of the course. Unless otherwise noted, each lecture begins at 16:00 GMT and runs for about two hours, depending on the topics covered.

For those who cannot attend the lectures at those times, the lectures will be recorded and placed on the course website as AVI video files each day, within one day. Students will also be able to communicate with the instructor and other students via the course forums. Lecture attendance is therefore not required.

Since this will be an interactive, hands-on workshop, all attendees will need a computer with a broadband Internet connection (1 Mbps or faster is strongly recommended for those watching the live lecture), a sound card with speakers, a modern Web browser, and Java. A microphone and webcam are not required but may be used.


This course is certified by the Bioinformatics Organization, Inc., the largest international affiliation in the field, and it will count as 6 "Continuing Scientific Education" (CSE) units (one unit per contact hour) within the Organization. Students completing the course will receive a certificate attesting to that.

Refund policy

For any course type, if a student is not satisfied with the conduct or content of a course, they may request a full refund within the first two days of lecture. After two days but within a week, a 50% refund will be granted. After one week, a 100% credit toward another course will be granted. No refunds or credits apply beyond those stated here.

Additional information

Please contact us for questions or additional information.

See also

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