| Protein | Protein Name | Molecular Type | Evidence | Reference |
|---|
| LPXN | Leupaxin | Adaptor Protein | Mediates prostate cancer cell adhesion in androgen dependent and independent cell line. | Reference |
| SMAD3 | SMAD family member 3 | Transcription Regulatory Protein | SMAD3 is associated with prostate cancer cell adhesion as a mediator of growth and differentiation factor-9(GDF-9) dependent signaling and activation of FAK and paxillin in PC-3 prostate cancer cells. | Reference |
| RAC1 | Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | GTPase | RAC1 plays an important role in human prostate cancer cell adhesion. | Reference |
| BAG3 | BCL2-associated athanogene 3 | Adaptor Protein | BAG3 regulates the adhesiveness in epithelial prostate cancer | Reference |
| GNB2L1 | Guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 | Adaptor Protein | Involved in prostate cancer cell adhesion through beta(1) integrin-RACK1-FAK-Src signaling axis in both androgen dependent and independent prostate cancer cell line; TROP-2 is a regulator of these signaling mediated event. | Reference |
| IRS1 | Insulin receptor substrate 1 | Adaptor Protein | IRS1 is involved in regulation of prostate cancer cell adhesion in LNCaP cells. | Reference |
| TGFBR2 | Transforming growth factor, beta receptor II | Receptor Serine/threonine Kinase | Loss of TGFBR2 responsiveness is involved in prostate cancer cell adhesion in bone matrix. | Reference |
| BMPR2 | Bone morphogenetic protein receptor, type II (serine/threonine kinase) | Receptor Serine/threonine Kinase | BMP9 causes in vitro inhibition of cell adhesion in prostate cancer and BMPR2 is required for its function | Reference |
| ERBB2 | V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 | Receptor Tyrosine Kinase | ERBB2 is involved with prostate cancer cell adhesion through ERBB2-PYK2-ERK/MAPK pathway in androgen responsive prostate cancer cell line. | Reference |
| EPHA2 | EPH receptor A2 | Receptor Tyrosine Kinase | EPHA2 is involved in regulation of cell adhesion and cytoskeletal rearrangement in prostate cancer. | Reference |
| IFNAR1 | Interferon (alpha, beta and omega) receptor 1 | Cytokine Receptor | IFNAR1 is involved in prostate cancer cell adhesion by modulation of cell adhesion molecule, ICAM1, Pcadherin and alpha integrin | Reference |
| CXCR4 | Chemokine (C-X-C motif) receptor 4 | G protein Coupled Receptor | CXCR4 enhances prostate cancer cell migration through alpha5 and beta3 integrins | Reference |
| SRC | V-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog | Tyrosine Kinase | Mediates prostate cancer cell adhesion through beta(1) integrin-RACK1-FAK-SRC signaling pathway in androgen dependent and independent prostate cancer cell line. | Reference |
| PXN | Paxillin | Cytoskeletal Associated Protein | Paxillin is involved in the prostate cancer cell adhesion in a GDF9 responsive way and SMAD dependent manner in PC-3 prostate cancer cell line. | Reference |
| BCAR1 | Breast cancer anti-estrogen resistance 1 | Adaptor Protein | Mediates formation of peripheral adhesion complex through PTK6-p130CAS-ERK5 signaling cascade. | Reference |
| PXN | Paxillin | Cytoskeletal Associated Protein | Involved in the regulation of prostate cancer cell adhesion in a alpha2 integrin mediated manner through FAK/src/paxillin/Rac/JNK signaling in androgen independent cell line. | Reference |
| TLN1 | Talin 1 | Cytoskeletal associated protein | Talin 1, overexpressed in human prostate cancer and plays a role in prostate cancer associated cell adhesion. | Reference |
| IL17 | Interleukin 17A | Cytokine | Interleukin-17 (IL-17) is involved in mediating adhesion of prostate cancer cells to the vascular endothelial cells through CD44-VCAM-1 interaction. | Reference |
| INS | Insulin | Growth Factor | Insulin (INS)/IGF1 plays a role in in mediating adhesion of prostate cancer cells to the vascular endothelial cells through CD44-VCAM-1 interaction. | Reference |
| RAP1A | RAP1A, member of RAS oncogene family | GTPase | RAP1A, which is upregulated in human prostate cancer, plays a role in prostate cancer cell adhesion as its critical negative regulator MiR-203 is significantly downregulated in human prostate cancer. | Reference |
| CXCL12 | Chemokine (C-X-C motif) ligand 12 | Chemokine | CXCL12 plays a significant role in modulation of human prostate cancer associated cell adhesion through regulating integrins. | Reference |
| ESL-1 | E-selectin ligand 1 | Integral Membrane Protein | E-selectin ligand 1(ESL-1) plays a significant role in human prostate cancer cell adhesion through activation of RAS and MAPK mediated signaling and there by promotes prostate cancer metastasis. | Reference |