Human Prostrate Cancer Hallmarks Map
Cancer Hallmark > Shape code- Hexagon depicts Adaptor protein, Round depicts-Receptor protein and Round Rectangle depicts other types of protein (e.g. Kinase etc). Color code- Red indicates positive perturbation, Green indicates negative perturbation and Yellow indicates no reported information associated with perturbation. Positive perturbation includes overexpression, amplification, up regulation and oncogenic activation (mutational activation). Negative perturbation includes deletion, loss of expression, genomic instability, epigenetic silencing, microRNA mediated silencing, aberrant splicing and down regulation. Edge represents physical interaction between two proteins as based on Human Reference Protein Database (HRPD) and literature mined information. Direction is given according to literature extracted information.Abbrevations