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Sequence Source Links |  |
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Database Satistics | |
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Drug Target 4 |
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Database Id : DDTB004 |
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| Target Name | Inosine-5'-Monophosphate Dehydrogenase - Dengue virus group Dengue virus type 2 | |||
| GenBank ID Protein | 1352865 | SwissProt ID | IMDH_TRIFO (P50097) | |
| Target Gene Name | IMPDH | |||
| Gene Sequence | View | GenBank ID Gene | L18917 | |
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| Protein Sequence | View | Number of Residues | 503 | |
| Molecular Weight | 55474 g/mol | Theoretical pI | 6.67 | |
| Function | catalytic activity | |||
| Process | ------------------ | Component | --------------------- | |
| Specific Function | Rate limiting enzyme in the de novo synthesis of guanine nucleotides and therefore is involved in the regulation of cell growth | |||
| Pathway map | map00230 Purine metabolism | |||
| Reaction | inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH + H+ | |||
| Pfam Domain Function | PF00571 CBS PF00478 IMPDH |
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| Transmembrane Regions | 365-384 | |||
| PDB file Link | 1ME7 | Download PDB File | 1ME7 | |
| 3D Structure Image | View | Cellular Location | Membrane | |
| References | ||||
