BTG1

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BTG1

OMIM	GENE CARDS	CGAP
109580	BTG1	77054

SYNONYMS

B-cell translocation gene 1, anti-proliferative

Protein Sequence

Cell Cycle

The leukemia-associated protein Btg1 and the p53-regulated protein Btg2 interact with the homeoprotein Hoxb9 and enhance its transcriptional activation Prevot D, Voeltzel T, Birot AM, Morel AP, Rostan MC, Magaud JP, Corbo L.

Cell Location

Identification of functional domains involved in BTG1 cell localization Rodier A, Rochard P, Berthet C, Rouault JP, Casas F, Daury L, Busson M, Magaud JP, Wrutniak-Cabello C, Cabello G.

Chromosome Human

A chromosome 12 coding region is juxtaposed to the MYC protooncogene locus in a t(8;12)(q24;q22) translocation in a case of B-cell chronic lymphocytic leukemia Rimokh R, Rouault JP, Wahbi K, Gadoux M, Lafage M, Archimbaud E, Charrin C, Gentilhomme O, Germain D, Samarut J, et al.

DNA Binding

The leukemia-associated protein Btg1 and the p53-regulated protein Btg2 interact with the homeoprotein Hoxb9 and enhance its transcriptional activation Prevot D, Voeltzel T, Birot AM, Morel AP, Rostan MC, Magaud JP, Corbo L.

Function

In search of a function for the TIS21/PC3/BTG1/TOB family Matsuda S, Rouault J, Magaud J, Berthet C.

Protein Binding

The leukemia-associated protein Btg1 and the p53-regulated protein Btg2 interact with the homeoprotein Hoxb9 and enhance its transcriptional activation Prevot D, Voeltzel T, Birot AM, Morel AP, Rostan MC, Magaud JP, Corbo L.

Protein Structure

Identification of functional domains involved in BTG1 cell localization Rodier A, Rochard P, Berthet C, Rouault JP, Casas F, Daury L, Busson M, Magaud JP, Wrutniak-Cabello C, Cabello G.

Signaling Pathway

Relationships of the antiproliferative proteins BTG1 and BTG2 with CAF1 Prevot D, Morel AP, Voeltzel T, Rostan MC, Rimokh R, Magaud JP, Corbo L.

Tumor Gene Type

BTG1, a member of a new family of antiproliferative genes Rouault JP, Rimokh R, Tessa C, Paranhos G, Ffrench M, Duret L, Garoccio M, Germain D, Samarut J, Magaud JP.

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