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TAL1

       

OMIM GENE CARDS CGAP
187040 TAL1 73828

 

SYNONYMS T-cell acute lymphocytic leukemia 1 (NOTE: redefinition of symbol)
SCL
TCL5

    

Nucleotide Sequence

 

Biochemical  Type 

Cell Cycle

        

Cell Location

  • Two models proposed for the molecular mechanism by which the Tal1 oncogene causes T cell acute lymphoblastic leukemia Park ST, Nolan GP, Sun XH.

           

Cell Type Distribution

  • TAL1, TAL2 and LYL1: a family of basic helix-loop-helix proteins which is a potential mediator of T cell leukaemogenesis. Baer R.

Clinical

Development

  • SCL gene is the most common molecular abnormality found in human T cell leukaemia Robb L, Begley CG.

 

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