GUSB

 

SYNONYMS glucuronidase, beta

Chromosome human Localization by fluorescence in situ hybridization of the human functional beta-glucuronidase gene (GUSB) to 7q11.21 --> q11.22. Speleman F, Vervoort R, van Roy N, Liebaers I, Sly WS, Lissens W.

Analysis of beta-glucuronidase levels in blood leucocytes of our patients has helped more precisely to assign this gene locus to 7q21.11 or 7q22.1. Fagan K, Gill A, Henry R, Wilkinson I, Carey B. PMID: 2486209 [PubMed - indexed for MEDLINE]

The human gene for beta glucuronidase is on chromosome 7. Francke U.

Clinical Expression and function of beta-glucuronidase in pancreatic cancer: potential role in drug targeting. Sperker B, Werner U, Murdter TE, Tekkaya C, Fritz P, Wacke R,Adam U, Gerken M,Drewelow B, Kroemer HK.

Development Histochemistry of enzymes in the pancreas of human embryos. Lichnovsky V, Lojda Z.

General Deletion mapping of plasminogen activator inhibitor, type I (PLANH1) and beta-glucuronidase (GUSB) in 7q21----q22. Schwartz CE, Stanislovitis P, Phelan MC, Klinger K, Taylor HA, Stevenson RE.

Oncogenic activation beta-Glucuronidase appeared less sensitive and was significantly elevated (100%)only in patients with pancreas cancer. Severini G, Diana L, Di Giovannandrea R, Tirelli C.

Regulation we found a significantly increasedspecific beta-glucuronidase activity (P<0.05) in pancreatic cancer. Sperker B, Werner U, MurdterTE, Tekkaya C, Fritz P,WackeR,Adam U, Gerken M,Drewelow B, Kroemer HK.