[BiO BB] How to rank active site(s) ?

[Shameer Khadar]

Dear All,

Is there any computational tool/protocol available to rank active site(s)
present in a protein. I am looking in to a couple of proteins which have
multiple site (say active site / binding sites ), I am looking for a method
to rank binding/Active sites. I have done with an extended google search. I
couldnt find anything as such. I would appreciate if any one can point me to
any  similar work / paper / tool etc .

Many thanks in advance,
Shameer Khadar
NCBS-TIFR