[BiO BB] protein merge

Dan Bolser dan.bolser at gmail.com
Mon Mar 15 13:21:07 EDT 2010


Isn't this just sequence (or structure) alignment?

The consensus would then be the merged sequence.

You should be able to find lots of alignment tools out there.



On 15 March 2010 15:57, Rafik Ouerchefani <rafik at ubuntu.com> wrote:
>
> Hello,
>
> I'm looking for a software that can merge two proteins with a shared domain
> (given .pdb files).
> With sequences it would be like this :
>
> seq 1 :  MSARIATRRRDKKARRKLQ*ELGATRLVVHRT*
> seq 2 :  *ELGATRLVVHRT*PRHIYAPNGSEVLVQVIAA
> result : MSARIATRRRDKKARRKLQ*ELGATRLVVHRT*PRHIYAPNGSEVLVQVIAA
>
> These two sequences have a common sequence ELGATRLVVHRT (end of the first
> and beginning of the second). It's easy with sequences but I have to do it
> with 3D structures. I have the 3D structures of both sequences 1 and 2.
>
> Thanks,
>
> - Rafik
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