Hi when I try to run any emboss application, I obtained the following error: error while loading shared libraries: libnucleus.so.0: cannot open shared object file: no such file or directory. but the file is located at /opt/BioBrew/EMBOSS/2.6.0/lib/ Any idea why I get this error? thank you Khalil ----------------------------------------------------------------------- THIS E-MAIL MESSAGE IS INTENDED ONLY FOR THE USE OF THE INDIVIDUAL OR ENTITY TO WHICH IT IS ADDRESSED AND MAY CONTAIN INFORMATION THAT IS PRIVILEGED, CONFIDENTIAL AND EXEMPT FROM DISCLOSURE. If the reader of this E-mail message is not the intended recipient, you are hereby notified that any dissemination, distribution or copying of this communication is strictly prohibited. If you have received this communication in error, please notify us immediately at ablynx at ablynx.com. Thank you for your co-operation. -----------------------------------------------------------------------