At Massachusetts General Hospital, we are looking to set up a local blast server, preferably with the NCBI algorithm, on a computing cluster. We have installed the OSCAR clustering package http://sourceforge.net/projects/oscar/ on a small test cluster of computers running Red Hat Linux 7.2 on Intel. Does anyone know of an open source blast-for-cluster package that would run under this cluster management suite or is there a commercial package you are already running that you think is worthwhile??? We are also considering Apple's Xserve with the G4 accelerated blast to compare against the above system. -- Lance Davidow, PhD Director of Bioinformatics Dept of Molecular Biology Mass General Hospital Boston MA 02114 davidow@molbio.mgh.harvard.edu 617.726-5955 Fax: 617.726-6893