Hi, A reminder: this is coming from a total newbie at this BioCluster stuff. it is also to serve as the seed of a tutorial/history-of-building site for our creation. I am a total newbie in UNIX administration and installation. This is why we will get a system administrator to help us out. But I still have to figure out the right questions to ask!! OTHER SOFTWARES Besides BLAST, what other bioinfo software are known to work in cluster config? I would imagine that FASTA, the HMMER suite and any software that work in embarrassingly parallel fashion will. Anybody has experience running multi-softwarer clusters? Also, can a cluster do let's say, BLAST and RNA folding together? or BLAST and molecular modelling? At 8 nodes, we will concentrate on BLAST but we are planning a 32 nodes stage soon afterward and the demand is there. CLUSTERS HELPING CLUSTERS Another point that has been raised in our group is the fact that if some clusters might be less busy than others, is it possible for the head of the busy one to get help from the nodes of a less busy cluster? I ask because our projected cluster is to be a public-access resource. Another cluster is also planned for philogeny analysis by a group in the same department. In exchange for maintaining a mirror of GenBank, they are offering some of their horsepower to us. Is this feasible? Am I missing something? This is open for helpful and constructive discussion I know that lots of my questions have been asked before but I found some of the answers to be very cryptic. By pooling my questions in this multipost, I invite discussion on the hows of putting a BioCluster together for the less technically inclined among us! Sylvain ++++++++++++++++++++++++++++++++++++++++++++++++++++++++ Sylvain Foisy, Ph. D. Manager BIONEQ - Le Reseau quebecois de bioinformatique Genome-Quebec Tel.: (514) 343-6111 poste 5188 E-mail: foisys@medcn.umontreal.ca ++++++++++++++++++++++++++++++++++++++++++++++++++++++++