Hey Steve- I realized I babbled without specifically answering your question... A reasonable (free) approach would be to go with GridEngine on RedHat and use the 'qrsh' command to execute your blast jobs. I've only done one GridEngine install so far (my writeup of that experience is online at http://bioteam.net/dag/biocluster-diary-1/) but my impression and experiences with the product have been very positive. -Chris -- Chris Dagdigian, <dag@sonsorol.org> Independent life science IT & research computing consulting Office: 617-666-6454, Mobile: 617-877-5498, Fax: 425-699-0193 Work: http://BioTeam.net PGP KeyID: 83D4310E Yahoo IM: craffi