We have a PowerEdge 4600 server running RedHat 9. The system spec is given below. Server Specs: Dell PowerEdge 4600 Intel Xeon 2800 MHz Processor 4096 MB ECC DDR Ram 512 Cache 2 x 146 GB SCSI hard disks (RAID 0) OS : RedHat 9 (kernel 2.4.20-8), file system - ext3 The main usage of this server is for bioinformatics computational work. Clients run search/match C or C++ programs on this server through protocols like ssh. The no of clients will be not more than 4. This server is also acting as a file server for the same clients. T Get 3 newhe performance is not satisfactory so we are planning to do some modification in the configuration. One of our plan is promote a client workstation(dell precision-340, 1.5 GHz & 1GB ram) to a file server and switch the two SCSI hard disk from the PowerEdge server to this workstation. Add 3 new SCSI hard disk (37 GB) to the PowerEdge server and set a RAID 0, if possible also add a second identical processor to the server. We are interested to know if this will improve the performance of the computational server. Also it would be helpful if you could suggest any other alternatives for improving the computational performance for bioinformatics work. If any of you have poweredge 4600 please share your experience and ur system configuration. Suggestions on disk partitioning, kernel and file system to use will also be helpful Thanks for your time and help Karthik PS: We are more interested to improve the computational power than file handling!