One doesn't have to have a thesis topic already selected, but it helps to know whether you are interested in protein structure, DNA microarrays, phylogenetics trees, disease associations of genes, ancestral genome reconstruction, cell modeling, regulatory networks, synthetic biology, or some of the many other branches of bioinformatics, as no place can do them all. Once you have identified 5 topics that seem particularly interesting to you, find out the top 3 or 4 places where each is done. Places that do more things that interest you should be higher on your priority list, as you are actually somewhat unlikely to end up where your interest is first caught. ------------------------------------------------------------ Kevin Karplus karplus at soe.ucsc.edu http://www.soe.ucsc.edu/~karplus Professor of Biomolecular Engineering, University of California, Santa Cruz Undergraduate and Graduate Director, Bioinformatics (Senior member, IEEE) (Board of Directors & Chair of Education Committee, ISCB) life member (LAB, Adventure Cycling, American Youth Hostels) Effective Cycling Instructor #218-ck (lapsed) Affiliations for identification only.