[ssml] Re: pdb-l: entropy for matrix
Kevin Karplus
karplus at soe.ucsc.edu
Wed Sep 3 12:27:35 EDT 2003
The entropy of a substitution matrix tells you how much it generalizes
away from the single sequence it starts with.
Read
@article{altschul91,
author = "Stephen F. Altschul",
title = "Amino acid substitution matrices from an information theoretic perspective",
pages = "555--565",
journal = jmb,
volume = "219",
year = "1991"
}
A quick google search found tables relating PAM values and
entropy:
http://www.psc.edu/biomed/genedoc/gdpid.htm
http://www-bioeng.ucsd.edu/research/research_groups/compbio/workshop/Lab_3/matrix_entropy.htm
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