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Database Satistics | |
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Drug Target 2 |
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Database Id : DDTB002 |
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| Target Name | Inosine-5'-Monophosphate Dehydrogenase - Dengue virus group Dengue virus type 2 | |||
| GenBank ID Protein | 1352865 | SwissProt ID | IMDH_TRIFO (P50097) | |
| Target Gene Name | IMPDH | |||
| Gene Sequence | View | GenBank ID Gene | L18917 | |
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| Protein Sequence | View | Number of Residues | 503 | |
| Molecular Weight | 55428 g/mol | Theoretical pI | 6.68 | |
| Function | catalytic activity | |||
| Process | N/A | Component | N/A | |
| Specific Function | Rate limiting enzyme in the de novo synthesis of guanine nucleotides and therefore is involved in the regulation of cell growth | |||
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| Reaction | inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH + H+ | |||
| Pfam Domain Function | ||||
| Transmembrane Regions | 365-384 | |||
| PDB file Link | 1ME8 | Download PDB File | 1ME8 | |
| 3D Structure Image | View | References | ||
