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Related Drug Target
Target Name Laccase
GenBank ID Protein   GenBank ID Gene  
Target Gene Name LAC2
Protein Sequence
(Fasta format)

> Laccase
EPTCNTPSNRACWSDGFDINTDYEVSTPDTGVTQSYVFNLTEVDNWM
GPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHW
HGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRARQYGTSWYHSH
FSAQYGNGVVGTIQINGPASLPYDIDLGVFPITDYYYRAADDLVHFTQ
NNAPPFSDNVLINGTAVNPNTGEGQYANVTLTPGKRHRLRILNTSTEN
HFQVSLVNHTMTVIAADMVPVNAMTVDSLFLAVGQRYDVVIDASRAP
DNYWFNVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEGTPPVDH
QCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNG
SDINVDWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEG
PFSLPHPMHLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNP
PRRDTTMLPAGGWLLLAFRTDNPGAWLFHCHIAWHVSGGLSVDFLERP
ADLRQRISQEDEDDFNRVCDEWRAYWPTNPYPKIDSGL
Synonyms
1.Laccase II precursor
2.EC 1.10.3.2
3.Benzenediol:oxygen oxidoreductase
4.Urishiol oxidase
5.Diphenol oxidase
6.Laccase C
Number of Residues 559
Molecular Weight 61792 g/mol Theoretical pI 4.77
Function Secondary metabolites biosynthesis, transport and catabolism
Cellular Location Secreted
Specific Function
Probably involved in lignin degradation and in the detoxification of lignin-derived products in its natural habitat (herbivorous dung), which is rich in lignin of grasses and straw. Probably involved in melanin synthesis and in perithecia development
PDB file Link
1GW0
Download PDB File 1GW0
Structure  
3D Structure Image  
References
8914515

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