Related Drug Target |
| Target Name |
Interleukin-12 Beta Chain |
| GenBank ID Protein |
180626 |
GenBank ID Gene |
M65272 |
| Target Gene Name |
IL12B |
Protein Sequence
(Fasta format) |
> Interleukin-12 Beta Chain
IWELKKDVYVVELDWYPDAPGEMVVLTCDTPEEDGITWTLDQSSEVL
GSGKTLTIQVKEFGDAGQYTCHKGGEVLSHSLLLLHKKEDGIWSTDIL
KDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDLTFSVKSSRGSSD
PQGVTCGAATLSAERVRGDNKEYEYSVECQEDSACPAAEESLPIEVM
VDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPLKNSRQVEVSWEYP
DTWSTPHSYFSLTFCVQVQGKSKREKKDRVFTDKTSATVICRKNASIS
VRAQDRYYSSSWSEWASVPCS |
|
| Synonyms |
1.Interleukin-12 beta chain precursor
2.IL-12B
3.Cytotoxic lymphocyte maturation factor 40 4.kDa subunit
5.CLMF p40
6.NK cell stimulatory factor chain 2
7.NKSF2 |
|
| Number of Residues |
306 |
| Molecular Weight |
34697 g/mol |
Theoretical pI |
5.29 |
| Function |
|
| Cellular Location |
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| Specific Function |
Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine- activated killer cells, and stimulate the production of IFN-gamma by resting PBMC |
|
| PDB file Link |
|
Download PDB File |
1F42 |
| Structure |
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| 3D Structure Image |
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| References |
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