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CR1
OMIM | GENE CARDS | CGAP |
120620 | CR1 | 193716 |
SYNONYMS | CD35 |
complement component (3b/4b) receptor 1, including Knops blood group system |
Clinical
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Development
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DNA Binding
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Function
In CML patients, the evidence of a direct relationship between lytic activity and antigen receptor levels seems to further support the involvement of CR1 molecules in tumor cell lysis, function. Lanza F, Castoldi G.
Characterization of the human neutrophil C1q receptor and functional effects of free ligand on activated neutrophils. Eggleton P, Ghebrehiwet B, Coburn JP, Sastry KN, Zaner KS, Tauber AI.
Soluble CR1 is increased in patients with leukemia and after administration of granulocyte colony-stimulating factor. Sadallah S, Lach E, Schwarz S, Gratwohl A, Spertini O, Schifferli JA.
Glycosylation is important for the proper expression of CR1 function. Lublin DM, Griffith RC, Atkinson JP.
A dysfunctional Mo1 glycoprotein is present on a subline of the KG1 acute myelogenous leukemia cell line. Dana N, Todd RF 3rd, Colten HR, Arnaout MA.
C3b receptors mediate the growth factor-induced proliferation of malignant B-chronic lymphocytic leukemia lymphocytes. Caligaris-Cappio F, Schena M, Bergui L, Tesio L, Riva M, Rege-Cambrin G, Funaro A, Malavasi F.
Ligand Binding
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Phenotype
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Regulation
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