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HOX11

                                                    

OMIM GENE CARDS CGAP
186770 HOX11 89583

 

SYNONYMS TCL3
homeo box 11 (T-cell lymphoma 3-associated breakpoint)

      

Protein Sequence

 

Biochemical  Type 

Cell Cycle

Cell Location

  • Joining of recombination signals on the der 14q- chromosome in T-cell acute leukemia with t(10;14) chromosome translocation  Kagan J, Joe YS, Freireich EJ.

Chromosome Human

  • Sequence of 10q24 locus surrounding the HOX11 oncogene reveals a new gene HUG1 expressed in a T-ALL cell line  Watt PM, Kumar R, Kees UR.

Chromosome Mouse

  • A Drosophila melanogaster homologue of the T-cell oncogene HOX11 localises to a cluster of homeobox genes  Dear TN, Rabbitts TH.

Development

  • A Drosophila melanogaster homologue of the T-cell oncogene HOX11 localises to a cluster of homeobox genes  Dear TN, Rabbitts TH

DNA Binding

  • The optimal binding sequence of the Hox11 protein contains a predicted recognition core motif  Tang S, Breitman ML.

DNA  Structure

  • Genomic organization of the putative human homeobox proto-oncogene HOX-11 and its endogenous expression in T cells  Lu M, Zhang N, Ho AD.

Function

  • Homeobox genes in normal hematopoiesis and leukemogenesis  Chiba S.

Homologue

  • A Drosophila melanogaster homologue of the T-cell oncogene HOX11 localises to a cluster of homeobox genes  Dear TN, Rabbitts TH.

Oncogenic  Activation

Phenotype

Regulation

  • Homeobox genes in normal hematopoiesis and leukemogenesis  Chiba S.

Tumor Gene Type

Tumor Type

  • Homeobox genes in normal hematopoiesis and leukemogenesis  Chiba S.

 

 

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