LMO1
Chromosome Human
The t(11;14)(p15;q11) in a T-cell acute lymphoblastic leukemia cell line activates multiple transcripts, including Ttg-1, a gene encoding a potential zinc finger protein McGuire-E-A. Hockett-R-D. Pollock-K-M. Bartholdi-M-F. OBrien-S-J. Korsmeyer-S-J. Mol-Cell-Biol 9: 2124-2132 (1989)
Oncogenicity
Thymic overexpression of Ttg-1 in transgenic mice results in T-cell acute lymphoblastic leukemia/lymphoma McGuire-E-A. Rintoul-C-E. Sclar-G-M. Korsmeyer-S-J. Mol-Cell-Biol 12: 4186-96 (1992)