MLLT3

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MLLT3

OMIM	GENE CARDS	CGAP
159558	MLLT3	404

SYNONYMS	AF-9
	myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 3

Cell Cycle

N-terminal portion common to various MLL-chimeric products plays an important role in leukemogenesis Joh T, Kagami Y, Yamamoto K, Segawa T, Takizawa J, Takahashi T, Ueda R, Seto M.

Chromosome Human

Identification of MLL and chimeric MLL gene products involved in 11q23 translocation Joh T, Kagami Y, Yamamoto K, Segawa T, Takizawa J, Takahashi T, Ueda R, Seto M.

A new type of complex variant translocation of t(9;11)(p22;q23) with MLL rearrangement Takahashi N, Miura I, Ohshima A, Nimura T, Hashimoto K, Hatano Y, Utsumi S, Kume M, Saito K, Kobayashi Y, Saito M, Seto M, Ueda R, Miura AB.

Acute myelomonocytic leukemia after treatment with chronic oral etoposide: are MLL and LTG9 genes targets for etoposide Goto H, Shimazaki C, Tatsumi T, Yamagata N, Inaba T, Fujita N, Moriguchi T, Yamamoto K, Seto M, Ueda R, et al.

The MLLT3 gene maps between D9S156 and D9S171 and contains an unstable polymorphic trinucleotide repeat Walker GJ, Walters MK, Palmer JM, Hayward NK.

MLLT3 gene on 9p22 involved in t(9;11) leukemia encodes a serine/proline rich protein homologous to MLLT1 on 19p13 Iida S, Seto M, Yamamoto K, Komatsu H, Tojo A, Asano S, Kamada N, Ariyoshi Y, Takahashi T, Ueda R.

Clinical

Acute myelomonocytic leukemia after treatment with chronic oral etoposide Goto H, Shimazaki C, Tatsumi T, Yamagata N, Inaba T, Fujita N, Moriguchi T, Yamamoto K, Seto M, Ueda R, et al.

Function

Identification of MLL and chimeric MLL gene products involved in 11q23 translocation and possible mechanisms of leukemogenesis by MLL truncation Joh T, Kagami Y, Yamamoto K, Segawa T, Takizawa J, Takahashi T, Ueda R, Seto M.

Production of chimeric mRNA following the translocation of the LTG9 (MLLT3/AF9) gene at 9p22 to 11q is a critical event in this leukemia Takahashi N, Miura I, Ohshima A, Nimura T, Hashimoto K, Hatano Y, Utsumi S, Kume M, Saito K, Kobayashi Y, Saito M, Seto M, Ueda R, Miura AB.

Tumor Gene Type

Identification of MLL and chimeric MLL gene products involved in 11q23 translocation and possible mechanisms of leukemogenesis by MLL truncation Joh T, Kagami Y, Yamamoto K, Segawa T, Takizawa J, Takahashi T, Ueda R, Seto M.

A new type of complex variant translocation of t(9;11)(p22;q23) with MLL rearrangement Takahashi N, Miura I, Ohshima A, Nimura T, Hashimoto K, Hatano Y, Utsumi S, Kume M, Saito K, Kobayashi Y, Saito M, Seto M, Ueda R, Miura AB.

MLL gene at 11q23 was found to be involved in a subset of leukemias with an 11q23 abnormality Iida S, Seto M, Yamamoto K, Komatsu H, Tojo A, Asano S, Kamada N, Ariyoshi Y, Takahashi T, Ueda R.

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