Hi, So,let's start. A reminder: this is coming from a total newbie at this BioCluster stuff. it is also to serve as the seed of a tutorial site for building the beast. THE HARDWARE -> CPU: I have seen some debate on this list about PIII vs Athlon as CPUs, especially about power requirements as well as the heat outputs. Since our cluster is to be small (at first; we do have some ambitions!), it has got to have the more bangs for the bucks that we can get. To try to minimize heat output problems, we are inclined to choose processors that are not pushing the current speed limit. We are looking into dual-processor nodes and head with speed of 1.2-1.5GHz. Which one would be the a reasonable choice: a) PIII/512kb cache (Tualatin) at 1.4 GHz b) Athlon MP at 1.2-1.5GHz -> RAM: We are inclined to load the max possible for our selected motherboards (Tyan) at 4Gig. DDR-RAM of course. Not much debate here. -> HD space: If I read the list archive right, space is needed so that parts of GenBank (or any other DB) can reside in each node for BLAST to do its thing. The choice is either to use built-in ATA-100 interface to 40GB 7.2K drives or optional SCSI interface for a 36GB 10K drive(our selected options right now). Since (unless I am mistaken) BLAST could be slowed down by I/O issues, I would be more willing to buy SCSI even if it is more expensive. Another question : how much space would the head needs? ->Mass storage: we are thinking about a rackmounted NAS solution, with about 360-480 GB of space. I think that is is the most cost-effective method and an easy expendable one too. Anybody has any experience with particular NAS? ->Interface card: Yeah, Myrinet would be great. Back to Earth: we are thinking either 100Base-T or Gigabit Ethernet (most probably the first one). Can we work with the built-in NIC interface of the motherboard or should we get PCI NIC cards? What features would a NIC card need to be a useful solution (for example: net boot of nodes from the head)? Evidently, the head is going to need 2 cards. ->Networking gear: all this will be linked together to the head via a rackmounted switch. I heard great things about the Cisco stuff. How about 3Com? Other choices out there? ->Enclosures: all rackmounted with 2U enclosures, except for the head who is going to be a tower enclosure with DVD/CD-RW drive, possibly a DLT tape drive too. We intend to start with 8 nodes and planning to build it up to 32 or 48 enclosures (total of 96 node processors). ->Physical installations: we are no engineers so what would we need, in AC and electrical power inputs? We are planning to retrofit a former office into a server room. Anybody with similar experience? This is open for helpful and constructive discussion Sylvain ++++++++++++++++++++++++++++++++++++++++++++++++++++++++ Sylvain Foisy, Ph. D. Manager BIONEQ - Le Reseau quebecois de bioinformatique Genome-Quebec Tel.: (514) 343-6111 poste 5188 E-mail: foisys@medcn.umontreal.ca ++++++++++++++++++++++++++++++++++++++++++++++++++++++++