On 20 Apr 2005, at 2:25 pm, Joe Landman wrote: > Hi folks: > > Are computational bottlenecks the major problem you are running into > today? What do you see in the future in terms of rate limiting > efforts? If you had an "infinitely fast" cluster (like a blue-gene > from IBM), how would like impact your work/processes? The major bottlenecks are based around IO. We have plenty of CPU grunt. Scalable databases and parallel filesystems are what we need to sort out now. It's no use having infinite amounts of CPU power if you have to force all the output through a very tiny pipe. A lot of this can be solved by programming expertise, but most scientists aren't interested in coding for scalability, they're only interested in quickly producing something which produces "the right answer", whatever that means. Having scalable filesystems and databases would allow them to carry on coding in their current less-than-perfect ways and still maintain some half-decent performance. Tim -- Dr Tim Cutts Informatics Systems Group, Wellcome Trust Sanger Institute GPG: 1024D/E3134233 FE3D 6C73 BBD6 726A A3F5 860B 3CDD 3F56 E313 4233