Hi Jacquelyn: You should be able to use a Linux machine to do this quite cost effectively. The configuration of the machine depends strongly upon which databases you will be using, what type of searches you will be performing, and how many query sequences you have. Some simple rules of thumb: 1) Memory is cheap, and BLAST loves memory. Without knowing details, I cannot really guess where you need to be, but I tend to try to configure a minimum of 1 GB RAM. "Excess" RAM is used as a disk cache, which speeds up the calculation. I have used a machine for searches where 4GB was insufficient for all the indices of all the databases. This is problem dependent. Don't work with anything less than 512 MB. 2) Disk IO speed is cheap (using IDE RAID0), and databases can be indexed/manipulated faster on a better file system. 3) Network speed is important, hopefully you have a GigE connection for pulling down big databases, if not, a nice Intel EtherExpress Pro 100 Network card is a good choice. 4) CPU choice can incite "religious" wars, much like editor choice, etc. I use AMD Athlon XP's in my desktop boxes, Athlon MP's in my servers. You can use Pentium 4 with equal success. Just remember that CPU MHz does not correlate well with performance on all codes. Lower MHz does not mean slower, and higher MHz does not mean higher. Joe On Wed, 2002-10-30 at 16:12, Nguyen, Jacquelyn wrote: > Here is the email message that I sent to NCBI: > > At this time the Standalone WWW Blast server is only available on UNIX web servers. We don't have a UNIX server in-house and would like to buy one to use for the Standalone WWW Blast server. What is the minimum requirements (memories, hardware, software) to deploy the software? What kind of UNIX machine (HP or Sun) do I need? What kind of web server (weblogic or websphere)? > > I haven't received a response from them yet and I need the answer soon. So does anyone know the answer? Did anyone try to put the software on a LINUX server? If so, were there any difficulties versus on a Sun Unix server? > > Thanks > > > > ====================================================================== > This electronic message transmission and any attachments are > confidential and may constitute legally privileged information of > IGEN International, Inc. The information is intended for solely > the use of the individual or entity named above. If you are not > the intended recipient, you are hereby notified that any > disclosure, copying, distribution or the taking of any action in > reliance of this information is strictly prohibited. You are not > authorized to retain it in any form nor to re-transmit it, and > you should destroy this email immediately. > > If you have received this electronic transmission in error, > please notify us by telephone (800-336-IGEN) or by electronic > mail (by replying to this e-mail) immediately. > ===================================================================== > > _______________________________________________ > Biodevelopers mailing list > Biodevelopers at bioinformatics.org > https://bioinformatics.org/mailman/listinfo/biodevelopers -- Joseph Landman, Ph.D Scalable Informatics LLC email: landman at scalableinformatics.com web: http://scalableinformatics.com phone: +1 734 612 4615