Hi All, I have been using the Web Services at NCBI for a variety of things, but have run into a bunch of problems today. The worst of these is that a service which used to return nucleic acid sequences is now returning protein sequences! I am using http://eutils.ncbi.nlm.nih.gov/entrez/eutils/soap/eutils.wsdl and running the methods "run_eFetch_MS" and "run_eFetch". run_eFetch_MS is not returning anything and run_eFetch is returning amino acid sequences where I have gotten nucleic acids in the past. I poke around NCBI's web site and can find no indication that they have changed anything on purpose. I also sent them an e-mail awhile back and have not yet heard from them (it has not been all that long). I just wondered if anyone else is having similar problems or knows what is going on. Thanks! Ethan Ethan Strauss Ph.D. Bioinformatics Scientist Promega Corporation 2800 Woods Hollow Rd. Madison, WI 53711 608-274-4330 800-356-9526 ethan.strauss at promega.com